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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
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Results for PRDM14
Z-value: 0.33
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Transcription factors associated with PRDM14
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| PRDM14 | hg38_v1_chr8_-_70071226_70071258 | 0.15 | 4.3e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of PRDM14
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_-_153094521 Show fit | 1.10 |
ENST00000368750.8
|
small proline rich protein 2E |
|
| chr1_-_153113507 Show fit | 0.82 |
ENST00000468739.2
|
small proline rich protein 2F |
|
| chr22_+_31093358 Show fit | 0.64 |
ENST00000404574.5
|
smoothelin |
|
| chr1_-_113887375 Show fit | 0.40 |
ENST00000471267.1
ENST00000393320.3 |
BCL2 like 15 |
|
| chr4_-_102345469 Show fit | 0.33 |
ENST00000356736.5
ENST00000682932.1 |
solute carrier family 39 member 8 |
|
| chr1_+_155033824 Show fit | 0.28 |
ENST00000295542.6
ENST00000423025.6 ENST00000368419.2 |
DC-STAMP domain containing 1 |
|
| chr13_+_108629605 Show fit | 0.28 |
ENST00000457511.7
|
myosin XVI |
|
| chr12_+_55932028 Show fit | 0.28 |
ENST00000394147.5
ENST00000551156.5 ENST00000553783.5 ENST00000557080.5 ENST00000432422.7 ENST00000556001.5 |
diacylglycerol kinase alpha |
|
| chr2_-_68871382 Show fit | 0.27 |
ENST00000295379.2
|
bone morphogenetic protein 10 |
|
| chr7_-_30026617 Show fit | 0.25 |
ENST00000222803.10
|
FKBP prolyl isomerase 14 |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.9 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.0 | 0.3 | GO:0060298 | positive regulation of sarcomere organization(GO:0060298) |
| 0.0 | 0.3 | GO:2000814 | regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814) |
| 0.0 | 0.3 | GO:0015691 | cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574) |
| 0.0 | 0.3 | GO:0021516 | dorsal spinal cord development(GO:0021516) |
| 0.1 | 0.2 | GO:0019364 | NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364) |
| 0.1 | 0.2 | GO:0071529 | cementum mineralization(GO:0071529) |
| 0.0 | 0.2 | GO:0061364 | chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834) apoptotic process involved in luteolysis(GO:0061364) |
| 0.0 | 0.2 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) positive regulation of lipoprotein metabolic process(GO:0050747) |
| 0.0 | 0.2 | GO:0002158 | osteoclast proliferation(GO:0002158) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.9 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 0.2 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
| 0.0 | 0.1 | GO:0005715 | late recombination nodule(GO:0005715) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.1 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.0 | 0.3 | GO:0031433 | telethonin binding(GO:0031433) |
| 0.0 | 0.3 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.1 | 0.2 | GO:0004608 | phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101) |
| 0.0 | 0.2 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.0 | 0.2 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 0.0 | 0.2 | GO:0048495 | Roundabout binding(GO:0048495) |
| 0.0 | 0.1 | GO:0036505 | prosaposin receptor activity(GO:0036505) |
| 0.0 | 0.1 | GO:0060002 | plus-end directed microfilament motor activity(GO:0060002) |
| 0.0 | 0.0 | GO:0043273 | CTPase activity(GO:0043273) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |