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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for PROX1

Z-value: 0.69

Motif logo

Transcription factors associated with PROX1

Gene Symbol Gene ID Gene Info
ENSG00000117707.16 PROX1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PROX1hg38_v1_chr1_+_213987929_2139879790.588.8e-04Click!

Activity profile of PROX1 motif

Sorted Z-values of PROX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PROX1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr20_-_7940444 4.24 ENST00000378789.4
hydroxyacid oxidase 1
chrY_+_20756103 2.65 ENST00000629237.2
ribosomal protein S4 Y-linked 2
chr4_+_127965429 2.34 ENST00000513371.1
ENST00000611882.1
abhydrolase domain containing 18
chr3_-_19934189 1.45 ENST00000295824.14
EF-hand domain family member B
chr16_+_4795378 1.05 ENST00000588606.5
small integral membrane protein 22
chr6_-_36024493 1.05 ENST00000394602.6
ENST00000355574.6
solute carrier family 26 member 8
chr16_+_4795357 1.02 ENST00000586005.6
small integral membrane protein 22
chr1_-_118185157 1.02 ENST00000336338.10
sperm associated antigen 17
chr5_-_35230332 0.97 ENST00000504500.5
prolactin receptor
chr2_+_127646145 0.96 ENST00000486700.2
ENST00000272644.7
G protein-coupled receptor 17
chr2_+_127645864 0.94 ENST00000544369.5
G protein-coupled receptor 17
chr21_-_7789509 0.93 ENST00000646133.1
small integral membrane protein 34B
chr3_+_158571171 0.92 ENST00000484955.5
ENST00000359117.9
ENST00000619577.5
ENST00000471745.5
ENST00000477042.6
ENST00000650753.1
ENST00000651984.1
ENST00000355893.11
ENST00000466246.7
ENST00000469452.5
ENST00000482628.5
myeloid leukemia factor 1
chr15_+_43517590 0.92 ENST00000300231.6
microtubule associated protein 1A
chr3_+_158571153 0.92 ENST00000491767.6
ENST00000618075.4
myeloid leukemia factor 1
chr3_+_158571215 0.91 ENST00000498592.6
ENST00000478894.7
myeloid leukemia factor 1
chr11_-_118152775 0.89 ENST00000324727.9
sodium voltage-gated channel beta subunit 4
chr7_-_138664224 0.86 ENST00000436657.5
SVOP like
chr3_-_138115594 0.85 ENST00000327532.7
ENST00000467030.5
DAZ interacting zinc finger protein 1 like
chr13_-_36214584 0.83 ENST00000317764.6
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr10_+_16436943 0.78 ENST00000423462.6
ENST00000378000.5
phosphotriesterase related
chr1_+_63523490 0.77 ENST00000371088.5
EF-hand calcium binding domain 7
chr10_+_16436996 0.74 ENST00000535784.7
phosphotriesterase related
chr10_-_46046264 0.70 ENST00000581478.5
ENST00000582163.3
microseminoprotein beta
chr1_+_241532121 0.70 ENST00000366558.7
kynurenine 3-monooxygenase
chr19_+_57769646 0.67 ENST00000391702.3
ENST00000598885.5
ENST00000598183.1
ENST00000599802.1
ENST00000396154.7
ENST00000396150.4
zinc finger protein 586
chr6_+_88047822 0.66 ENST00000237201.2
sperm acrosome associated 1
chr3_-_52770856 0.64 ENST00000461689.5
ENST00000535191.5
ENST00000383721.8
ENST00000233027.10
NIMA related kinase 4
chr11_-_30016945 0.64 ENST00000328224.7
potassium voltage-gated channel subfamily A member 4
chr11_-_64972070 0.62 ENST00000301896.6
membrane anchored junction protein
chr5_-_157142839 0.62 ENST00000286317.6
ENST00000524219.1
mediator complex subunit 7
hepatitis A virus cellular receptor 2
chr15_-_76012390 0.62 ENST00000394907.8
neuregulin 4
chr20_-_58228653 0.59 ENST00000457363.1
ankyrin repeat domain 60
chr10_-_121598359 0.59 ENST00000684153.1
fibroblast growth factor receptor 2
chr11_-_64972023 0.59 ENST00000530444.5
membrane anchored junction protein
chr10_-_90921079 0.58 ENST00000371697.4
ankyrin repeat domain 1
chr8_-_144605699 0.57 ENST00000377307.6
ENST00000276826.5
Rho GTPase activating protein 39
chr7_-_37448845 0.56 ENST00000310758.9
engulfment and cell motility 1
chr17_+_28319149 0.54 ENST00000226230.8
ENST00000583381.5
ENST00000582113.1
ENST00000582384.1
transmembrane protein 97
chr14_+_22314435 0.53 ENST00000390467.3
T cell receptor alpha variable 40
chr11_+_61392576 0.53 ENST00000515837.7
transmembrane protein 216
chr3_-_112499358 0.53 ENST00000383680.4
B and T lymphocyte associated
chr1_-_159076742 0.52 ENST00000368130.9
absent in melanoma 2
chr9_+_93058684 0.51 ENST00000617293.4
ENST00000375472.8
ENST00000465709.5
sushi domain containing 3
chr2_-_233013228 0.51 ENST00000264051.8
neuronal guanine nucleotide exchange factor
chr2_+_131105326 0.51 ENST00000438882.6
ENST00000404460.5
pleckstrin homology domain containing B2
chr11_+_61392360 0.50 ENST00000334888.9
ENST00000398979.7
transmembrane protein 216
chr11_+_46719193 0.50 ENST00000311907.10
ENST00000530231.5
ENST00000442468.1
coagulation factor II, thrombin
chr19_+_1354931 0.48 ENST00000591337.7
PWWP domain containing 3A, DNA repair factor
chr19_+_52336237 0.47 ENST00000403906.8
ENST00000321287.12
zinc finger protein 610
chr19_+_11814256 0.47 ENST00000304060.10
ENST00000457526.1
ENST00000427505.5
zinc finger protein 440
chr19_+_52336260 0.45 ENST00000601151.5
zinc finger protein 610
chr11_-_74170975 0.44 ENST00000539061.6
ENST00000680645.1
ENST00000334126.12
ENST00000680718.1
C2 domain containing 3 centriole elongation regulator
chr16_-_14694308 0.44 ENST00000438167.8
phospholipase A2 group X
chr3_-_64225436 0.44 ENST00000638394.2
prickle planar cell polarity protein 2
chr4_-_155866277 0.42 ENST00000537611.3
acid sensing ion channel subunit family member 5
chr10_+_14878848 0.42 ENST00000433779.5
ENST00000378325.7
ENST00000354919.11
ENST00000313519.9
ENST00000420416.1
suppressor of variegation 3-9 homolog 2
chr12_+_63779894 0.42 ENST00000261234.11
ribitol xylosyltransferase 1
chr22_+_24594781 0.41 ENST00000456869.5
ENST00000411974.5
gamma-glutamyltransferase 1
chr6_-_134174853 0.41 ENST00000475719.6
ENST00000367857.9
ENST00000237305.11
serum/glucocorticoid regulated kinase 1
chr7_+_64794388 0.41 ENST00000359735.7
zinc finger protein 138
chr5_+_65563239 0.40 ENST00000535264.5
ENST00000538977.5
ENST00000261308.10
peptidylprolyl isomerase domain and WD repeat containing 1
chr4_+_6782674 0.39 ENST00000307659.6
ENST00000425103.5
KIAA0232
chr16_+_31873772 0.39 ENST00000394846.7
ENST00000300870.15
zinc finger protein 267
chr7_+_64794415 0.38 ENST00000494380.5
ENST00000440155.6
ENST00000440598.2
ENST00000437743.1
ENST00000307355.12
zinc finger protein 138
chr12_-_52553139 0.37 ENST00000267119.6
keratin 71
chr16_+_11976709 0.37 ENST00000566228.6
sorting nexin 29
chr12_+_63780126 0.37 ENST00000537373.5
ribitol xylosyltransferase 1
chr2_-_106468326 0.37 ENST00000304514.11
ENST00000409886.4
RANBP2 like and GRIP domain containing 3
chr11_-_45286265 0.35 ENST00000020926.8
synaptotagmin 13
chrX_+_102307022 0.35 ENST00000604790.2
nuclear RNA export factor 2
chr8_-_86743626 0.35 ENST00000320005.6
cyclic nucleotide gated channel subunit beta 3
chr20_+_21126074 0.35 ENST00000619189.5
kizuna centrosomal protein
chr13_+_26557659 0.35 ENST00000335327.6
ENST00000361042.8
ENST00000671038.1
WASP family member 3
chr1_+_154993581 0.34 ENST00000392487.1
lens epithelial protein
chr4_+_127965361 0.34 ENST00000444616.5
abhydrolase domain containing 18
chr3_+_12484421 0.34 ENST00000681713.1
ENST00000679699.1
ENST00000446004.6
ENST00000679756.1
ENST00000681343.1
ENST00000415684.6
ENST00000412698.3
ENST00000454502.6
ENST00000284995.11
ENST00000402228.7
ENST00000680275.1
ENST00000681676.1
ENST00000681042.1
ENST00000679492.1
ENST00000680857.1
tRNA splicing endonuclease subunit 2
chr3_+_12484540 0.34 ENST00000680943.1
ENST00000680421.1
ENST00000679367.1
ENST00000679876.1
ENST00000444864.6
ENST00000680986.1
tRNA splicing endonuclease subunit 2
chr4_+_127965267 0.33 ENST00000398965.5
abhydrolase domain containing 18
chr20_+_21126037 0.32 ENST00000611685.4
ENST00000616848.4
kizuna centrosomal protein
chr4_-_127965930 0.32 ENST00000641447.1
ENST00000296468.8
ENST00000641134.1
ENST00000641147.1
ENST00000641178.1
major facilitator superfamily domain containing 8
chr7_+_100177897 0.32 ENST00000317296.9
ENST00000615138.5
ENST00000620100.5
ENST00000422690.5
ENST00000439782.1
stromal antigen 3
chr2_-_162071183 0.32 ENST00000678668.1
dipeptidyl peptidase 4
chr7_+_66629078 0.32 ENST00000449064.6
ENST00000638540.1
ENST00000640234.1
potassium channel tetramerization domain containing 7
chr1_-_202341926 0.31 ENST00000646651.1
ubiquitin conjugating enzyme E2 T
chr11_-_62689523 0.31 ENST00000317449.5
LRRN4 C-terminal like
chr7_+_91940970 0.31 ENST00000359028.7
A-kinase anchoring protein 9
chr11_-_74170792 0.31 ENST00000680231.1
ENST00000681143.1
ENST00000679906.1
ENST00000681310.1
ENST00000414160.7
ENST00000538361.2
C2 domain containing 3 centriole elongation regulator
chr2_-_151973780 0.31 ENST00000637514.1
ENST00000636350.1
ENST00000434468.2
ENST00000637762.1
ENST00000637779.1
ENST00000637547.1
ENST00000636901.1
ENST00000397327.7
ENST00000636721.1
ENST00000636380.1
ENST00000637284.1
ENST00000636617.1
ENST00000636947.1
ENST00000638091.1
ENST00000636108.1
ENST00000638040.1
ENST00000636773.1
ENST00000637418.1
ENST00000637216.1
calcium voltage-gated channel auxiliary subunit beta 4
chr8_+_116950951 0.31 ENST00000427715.2
solute carrier family 30 member 8
chr20_+_21125999 0.30 ENST00000620891.4
kizuna centrosomal protein
chr12_+_54008961 0.30 ENST00000040584.6
homeobox C8
chr20_+_21125981 0.30 ENST00000619574.4
kizuna centrosomal protein
chr3_+_52410635 0.30 ENST00000327906.8
PHD finger protein 7
chr6_+_158536398 0.29 ENST00000367090.4
transmembrane protein 181
chr11_+_64241600 0.29 ENST00000535135.7
ENST00000652094.1
FKBP prolyl isomerase 2
chr11_+_60842095 0.28 ENST00000227520.10
coiled-coil domain containing 86
chr6_+_116877236 0.28 ENST00000332958.3
regulatory factor X6
chr10_-_121598234 0.28 ENST00000369058.7
ENST00000369060.8
ENST00000359354.6
fibroblast growth factor receptor 2
chr16_+_28711417 0.28 ENST00000395587.5
ENST00000569690.5
ENST00000331666.11
ENST00000564243.5
ENST00000566866.5
eukaryotic translation initiation factor 3 subunit C
chr2_+_162318884 0.28 ENST00000446271.5
ENST00000429691.6
grancalcin
chr10_-_43574555 0.28 ENST00000374446.7
ENST00000535642.5
ENST00000426961.1
zinc finger protein 239
chr3_+_190388120 0.28 ENST00000456423.2
ENST00000264734.3
claudin 16
chr4_-_127965204 0.28 ENST00000513559.6
ENST00000641186.1
ENST00000641393.1
major facilitator superfamily domain containing 8
chr9_-_83921405 0.27 ENST00000297814.7
ENST00000334204.6
ENST00000413982.5
kinesin family member 27
chr2_+_131105296 0.27 ENST00000628582.2
pleckstrin homology domain containing B2
chr1_+_222644247 0.27 ENST00000340535.11
MIA SH3 domain ER export factor 3
chr10_-_94362925 0.27 ENST00000371361.3
NOC3 like DNA replication regulator
chr1_+_179293714 0.26 ENST00000540564.5
ENST00000539888.5
sterol O-acyltransferase 1
chr1_+_241532370 0.26 ENST00000366559.9
ENST00000366557.8
kynurenine 3-monooxygenase
chrX_-_137033991 0.26 ENST00000651716.2
G protein-coupled receptor 101
chr2_+_216633411 0.25 ENST00000233809.9
insulin like growth factor binding protein 2
chr1_+_179293760 0.25 ENST00000367619.8
sterol O-acyltransferase 1
chr18_+_36187483 0.25 ENST00000261326.6
molybdenum cofactor sulfurase
chr16_-_4752565 0.24 ENST00000588099.1
ENST00000588942.1
novel transcript
zinc finger protein 500
chr1_+_246566422 0.24 ENST00000366513.9
ENST00000366512.7
consortin, connexin sorting protein
chr1_+_173868350 0.24 ENST00000427304.5
ENST00000367702.1
zinc finger and BTB domain containing 37
chr19_-_44304968 0.24 ENST00000591609.1
ENST00000589799.5
ENST00000291182.9
ENST00000650576.1
ENST00000589248.5
zinc finger protein 235
chr2_-_53859929 0.24 ENST00000394705.3
ENST00000406625.6
G protein-coupled receptor 75
ankyrin repeat and SOCS box containing 3
chr4_-_127965133 0.24 ENST00000641558.1
ENST00000641590.1
ENST00000641503.1
ENST00000641482.1
ENST00000641743.1
ENST00000641369.1
ENST00000641949.1
ENST00000641695.1
ENST00000641509.1
ENST00000641243.1
ENST00000641686.2
ENST00000641690.1
ENST00000641228.1
ENST00000642042.1
major facilitator superfamily domain containing 8
chr5_+_146203593 0.23 ENST00000265271.7
RNA binding motif protein 27
chr15_+_38454103 0.23 ENST00000397609.6
ENST00000491535.5
family with sequence similarity 98 member B
chr16_-_11976611 0.23 ENST00000538896.5
ENST00000673243.1
nuclear pore complex interacting protein family member B2
chr1_-_27914513 0.23 ENST00000313433.11
ENST00000373912.8
ENST00000444045.1
replication protein A2
chr3_-_112499457 0.21 ENST00000334529.10
B and T lymphocyte associated
chr11_-_6481304 0.21 ENST00000254584.6
ENST00000525235.1
ENST00000396777.8
ENST00000445086.6
ADP ribosylation factor interacting protein 2
chr14_-_74302910 0.21 ENST00000556971.1
ENST00000356924.9
ATP binding cassette subfamily D member 4
chr5_-_157142745 0.21 ENST00000420343.1
mediator complex subunit 7
chr7_+_66629023 0.21 ENST00000639879.1
ENST00000640851.1
potassium channel tetramerization domain containing 7
chr4_-_120922648 0.21 ENST00000264808.8
PR/SET domain 5
chr13_-_36214521 0.21 ENST00000379881.8
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr1_-_246566238 0.21 ENST00000366514.5
transcription factor B2, mitochondrial
chr17_-_42121330 0.19 ENST00000225916.10
lysine acetyltransferase 2A
chr12_+_112791933 0.19 ENST00000551052.5
ENST00000415485.7
rabphilin 3A
chr2_-_151973991 0.19 ENST00000534999.6
ENST00000637217.1
ENST00000360283.11
calcium voltage-gated channel auxiliary subunit beta 4
chr21_-_25607474 0.19 ENST00000352957.9
ENST00000419219.1
ENST00000307301.11
mitochondrial ribosomal protein L39
chr10_+_110567666 0.18 ENST00000361804.5
structural maintenance of chromosomes 3
chr3_-_131026726 0.18 ENST00000514044.5
ENST00000264992.8
asteroid homolog 1
chr11_-_111879154 0.18 ENST00000260257.9
ferredoxin-fold anticodon binding domain containing 1
chr5_-_178996184 0.18 ENST00000650031.1
glutamate metabotropic receptor 6
chr22_-_44498179 0.18 ENST00000341255.4
retrotransposon Gag like 6
chr20_+_257716 0.18 ENST00000382376.4
defensin beta 132
chr2_-_97663920 0.17 ENST00000289228.7
actin related protein 1B
chr20_+_58389197 0.17 ENST00000475243.6
ENST00000395802.7
VAMP associated protein B and C
chr13_-_19782923 0.17 ENST00000338910.9
paraspeckle component 1
chr6_+_125781108 0.17 ENST00000368357.7
nuclear receptor coactivator 7
chr9_+_127397129 0.17 ENST00000610552.4
solute carrier family 2 member 8
chr8_+_109540075 0.17 ENST00000614147.1
ENST00000337573.10
estrogen receptor binding site associated antigen 9
chr6_-_42722590 0.16 ENST00000230381.7
peripherin 2
chr11_+_64241053 0.16 ENST00000309366.9
ENST00000449942.6
ENST00000652762.2
FKBP prolyl isomerase 2
novel protein
chr5_+_38258373 0.16 ENST00000354891.7
EGF like, fibronectin type III and laminin G domains
chr6_-_25042003 0.15 ENST00000510784.8
RHO family interacting cell polarization regulator 2
chr18_-_2571471 0.15 ENST00000574676.1
ENST00000574538.2
ENST00000319888.10
methyltransferase like 4
chr4_-_153759957 0.15 ENST00000508248.1
ENST00000347063.9
ring finger protein 175
chr5_-_22853320 0.15 ENST00000504376.6
ENST00000382254.6
cadherin 12
chr11_+_6497272 0.15 ENST00000254579.11
ENST00000354685.7
dynein heavy chain domain 1
chr12_-_43552196 0.15 ENST00000389420.8
ADAM metallopeptidase with thrombospondin type 1 motif 20
chr9_+_70258921 0.15 ENST00000361138.7
structural maintenance of chromosomes 5
chr2_+_100562941 0.15 ENST00000264254.11
phosducin like 3
chr15_-_58065703 0.15 ENST00000249750.9
aldehyde dehydrogenase 1 family member A2
chr12_-_121858849 0.15 ENST00000289004.8
4-hydroxyphenylpyruvate dioxygenase
chr7_-_91880672 0.15 ENST00000456229.1
ENST00000442961.1
ENST00000406735.6
ENST00000419292.1
ENST00000351870.8
mitochondrial transcription termination factor 1
chr12_-_117190456 0.14 ENST00000330622.9
ENST00000622495.5
ENST00000427718.6
F-box protein 21
chr7_+_66628864 0.14 ENST00000639828.2
ENST00000275532.8
ENST00000640385.1
potassium channel tetramerization domain containing 7
chr12_+_112791738 0.14 ENST00000389385.9
rabphilin 3A
chr8_+_109539816 0.14 ENST00000529931.1
estrogen receptor binding site associated antigen 9
chr5_+_146203544 0.13 ENST00000506502.2
novel readthrough transcript
chr2_+_17754116 0.13 ENST00000381254.7
ENST00000524465.5
ENST00000532257.1
GEN1 Holliday junction 5' flap endonuclease
chr4_+_150582119 0.13 ENST00000317605.6
mab-21 like 2
chr7_+_92528769 0.12 ENST00000481551.5
ENST00000265732.10
ENST00000496410.1
RNA binding motif protein 48
chr10_-_30999469 0.12 ENST00000538351.6
zinc finger protein 438
chr19_-_9435490 0.12 ENST00000592292.5
ENST00000588221.5
zinc finger protein 266
chr19_-_52857600 0.12 ENST00000596559.5
ENST00000594602.5
ENST00000595646.6
ENST00000597924.5
ENST00000243639.8
zinc finger protein 28
zinc finger protein 468
chr7_+_151062547 0.12 ENST00000392826.6
ENST00000461735.1
solute carrier family 4 member 2
chr15_-_58065734 0.11 ENST00000347587.7
aldehyde dehydrogenase 1 family member A2
chr12_+_49346911 0.11 ENST00000395069.3
DnaJ heat shock protein family (Hsp40) member C22
chr3_-_11846772 0.11 ENST00000455809.5
ENST00000444133.6
ENST00000273037.9
ENST00000630288.1
TAM41 mitochondrial translocator assembly and maintenance homolog
chr10_+_102245371 0.11 ENST00000676513.1
ENST00000676939.1
ENST00000677947.1
ENST00000677247.1
ENST00000369983.4
ENST00000678351.1
ENST00000679238.1
ENST00000677439.1
ENST00000677240.1
ENST00000677618.1
ENST00000673650.1
ENST00000674034.1
ENST00000676993.1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr10_-_67696115 0.10 ENST00000433211.7
catenin alpha 3
chr5_+_38258551 0.10 ENST00000322350.10
EGF like, fibronectin type III and laminin G domains
chr21_+_34364003 0.10 ENST00000290310.4
potassium voltage-gated channel subfamily E regulatory subunit 2
chr3_+_138348570 0.10 ENST00000423968.7
muscle RAS oncogene homolog
chr17_+_57105899 0.10 ENST00000576295.5
A-kinase anchoring protein 1
chr11_-_57530714 0.10 ENST00000525158.1
ENST00000257245.9
ENST00000525587.1
translocase of inner mitochondrial membrane 10
chr19_+_9178979 0.10 ENST00000642043.1
ENST00000641288.2
olfactory receptor family 7 subfamily D member 2
chr19_+_45406630 0.10 ENST00000309424.8
RNA polymerase I subunit G
chr16_-_23596277 0.09 ENST00000562133.5
ENST00000570319.5
ENST00000007516.8
NADH:ubiquinone oxidoreductase subunit AB1
chr1_+_171485520 0.09 ENST00000647382.2
ENST00000392078.7
ENST00000367742.7
ENST00000338920.8
proline rich coiled-coil 2C
chr15_-_31161157 0.09 ENST00000542188.5
transient receptor potential cation channel subfamily M member 1
chr6_-_158999748 0.09 ENST00000449822.5
radial spoke head 3
chr7_-_88220025 0.09 ENST00000419179.5
ENST00000265729.7
sorcin
chrX_+_12137409 0.08 ENST00000672010.1
FERM and PDZ domain containing 4
chr1_-_54764482 0.08 ENST00000371279.4
prolyl-tRNA synthetase 2, mitochondrial
chr14_+_73136418 0.08 ENST00000557356.5
ENST00000556864.5
ENST00000556533.5
ENST00000556951.5
ENST00000557293.5
ENST00000553719.5
ENST00000553599.5
ENST00000556011.5
ENST00000394157.7
ENST00000357710.8
ENST00000560005.6
ENST00000555254.5
ENST00000554131.5
ENST00000324501.10
ENST00000557037.5
presenilin 1
chr16_+_70454577 0.08 ENST00000572784.5
ENST00000574784.5
ENST00000571514.5
ENST00000288078.11
ENST00000378912.6
ENST00000573352.5
ENST00000576453.1
fucose kinase
chr8_+_109540602 0.08 ENST00000530629.5
ENST00000620557.4
estrogen receptor binding site associated antigen 9
chr9_+_111631300 0.08 ENST00000313525.4
DnaJ heat shock protein family (Hsp40) member C25
chr19_-_9435551 0.08 ENST00000651268.1
ENST00000592904.7
zinc finger protein 266
chr16_-_740980 0.08 ENST00000251588.7
cytosolic iron-sulfur assembly component 3
chr9_-_135961310 0.08 ENST00000371756.4
UBA domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.2 GO:0009441 glycolate metabolic process(GO:0009441)
0.3 2.8 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.3 1.0 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.2 0.6 GO:0071656 negative regulation of interleukin-3 production(GO:0032712) negative regulation of granulocyte colony-stimulating factor production(GO:0071656) negative regulation of macrophage colony-stimulating factor production(GO:1901257)
0.2 1.0 GO:0038161 prolactin signaling pathway(GO:0038161)
0.2 1.0 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.9 GO:0035603 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
0.1 0.7 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 0.5 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1 1.2 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.5 GO:0051801 cytolysis in other organism involved in symbiotic interaction(GO:0051801) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.1 0.4 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 1.4 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 1.0 GO:0019532 oxalate transport(GO:0019532)
0.1 0.5 GO:0021997 neural plate axis specification(GO:0021997)
0.1 0.5 GO:0070269 pyroptosis(GO:0070269)
0.1 0.3 GO:0009405 pathogenesis(GO:0009405)
0.1 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.3 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.1 0.5 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.1 GO:0006393 termination of mitochondrial transcription(GO:0006393)
0.0 0.4 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.0 0.7 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.0 0.3 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.1 GO:0034093 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.6 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.9 GO:0086016 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
0.0 0.3 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.2 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.2 GO:2001107 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.3 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.0 0.3 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.3 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.4 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.3 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.1 GO:0086073 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.2 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.1 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.3 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.4 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.3 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.6 GO:0035994 response to muscle stretch(GO:0035994)
0.0 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.0 0.3 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.6 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.4 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.3 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 0.3 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.6 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:0032049 cardiolipin biosynthetic process(GO:0032049)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:1990716 axonemal central apparatus(GO:1990716)
0.1 0.7 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 0.5 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 0.3 GO:0044307 dendritic branch(GO:0044307)
0.1 0.5 GO:0030893 meiotic cohesin complex(GO:0030893)
0.1 4.2 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.4 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.3 GO:0035841 new growing cell tip(GO:0035841)
0.0 1.2 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 1.0 GO:0036038 MKS complex(GO:0036038)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 2.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.3 GO:0071438 intercellular canaliculus(GO:0046581) invadopodium membrane(GO:0071438)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.7 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 1.0 GO:0031904 endosome lumen(GO:0031904)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0052853 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.2 1.0 GO:0004925 prolactin receptor activity(GO:0004925)
0.2 0.6 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 0.5 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 0.9 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 1.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.0 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.4 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.7 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 0.3 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.1 0.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.3 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 2.1 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.7 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.4 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.5 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 0.2 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 2.5 GO:0019843 rRNA binding(GO:0019843)
0.0 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.3 GO:0008430 selenium binding(GO:0008430)
0.0 0.6 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.2 GO:0098988 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.0 0.4 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.3 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.2 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.3 GO:0004935 adrenergic receptor activity(GO:0004935)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.9 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.4 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.6 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.9 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.8 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.5 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.6 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 3.6 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation