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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for PTF1A

Z-value: 0.58

Motif logo

Transcription factors associated with PTF1A

Gene Symbol Gene ID Gene Info
ENSG00000168267.7 PTF1A

Activity profile of PTF1A motif

Sorted Z-values of PTF1A motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PTF1A

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_150508099 1.86 ENST00000346569.6
ENST00000369047.9
extracellular matrix protein 1
chr1_+_150508074 1.85 ENST00000369049.8
extracellular matrix protein 1
chr7_+_142760398 1.65 ENST00000632998.1
serine protease 2
chr9_+_33795551 1.17 ENST00000379405.4
serine protease 3
chr14_-_106875069 0.92 ENST00000390639.2
immunoglobulin heavy variable 7-81 (non-functional)
chr8_-_124565699 0.77 ENST00000519168.5
MTSS I-BAR domain containing 1
chr20_+_45812576 0.69 ENST00000405520.5
ENST00000617055.4
ubiquitin conjugating enzyme E2 C
chr20_+_45812665 0.68 ENST00000352551.9
ubiquitin conjugating enzyme E2 C
chr20_+_46008900 0.68 ENST00000372330.3
matrix metallopeptidase 9
chr20_+_45812632 0.68 ENST00000335046.7
ENST00000356455.9
ENST00000243893.10
ubiquitin conjugating enzyme E2 C
chr4_+_40196907 0.66 ENST00000622175.4
ENST00000619474.4
ENST00000615083.4
ENST00000610353.4
ENST00000614836.1
ras homolog family member H
chr15_-_89221558 0.65 ENST00000268125.10
retinaldehyde binding protein 1
chr6_-_149923077 0.64 ENST00000367360.7
ENST00000479265.1
retinoic acid early transcript 1G
chr4_+_40197023 0.60 ENST00000381799.10
ras homolog family member H
chr11_-_1622093 0.60 ENST00000616115.1
ENST00000399682.1
keratin associated protein 5-4
chr16_+_46884675 0.57 ENST00000562132.5
ENST00000440783.2
glutamic--pyruvic transaminase 2
chr9_+_4985227 0.55 ENST00000381652.4
Janus kinase 2
chr19_+_41755520 0.54 ENST00000199764.7
CEA cell adhesion molecule 6
chr10_+_11823348 0.50 ENST00000277570.10
ENST00000622831.4
proline and serine rich 2
chr1_-_204685700 0.50 ENST00000367177.4
leucine rich repeat neuronal 2
chr8_+_32548303 0.49 ENST00000650967.1
neuregulin 1
chr19_+_11559429 0.49 ENST00000585493.5
zinc finger protein 627
chr14_-_76826229 0.49 ENST00000557497.1
angel homolog 1
chr8_+_32548210 0.48 ENST00000523079.5
ENST00000650919.1
neuregulin 1
chr14_-_106025628 0.47 ENST00000631943.1
immunoglobulin heavy variable 7-4-1
chr7_+_150991087 0.46 ENST00000461406.5
nitric oxide synthase 3
chr1_+_9997220 0.46 ENST00000294435.8
retinol binding protein 7
chr21_-_33588624 0.45 ENST00000437395.5
ENST00000453626.5
ENST00000303113.10
ENST00000303071.10
ENST00000432378.5
DNA replication fork stabilization factor DONSON
chr22_-_50085331 0.45 ENST00000395876.6
modulator of VRAC current 1
chr7_+_142749465 0.45 ENST00000486171.5
ENST00000619214.4
ENST00000311737.12
serine protease 1
chr10_+_97572493 0.44 ENST00000307518.9
ENST00000298808.9
ankyrin repeat domain 2
chr1_-_75611109 0.43 ENST00000370859.7
solute carrier family 44 member 5
chr7_+_142750657 0.41 ENST00000492062.1
serine protease 1
chr19_-_46023046 0.37 ENST00000008938.5
peptidoglycan recognition protein 1
chr20_-_45631235 0.36 ENST00000326000.2
WAP four-disulfide core domain 9
chr17_-_41098084 0.36 ENST00000318329.6
ENST00000333822.5
keratin associated protein 4-8
chr10_+_75111595 0.34 ENST00000671800.1
ENST00000542569.6
ENST00000372687.4
sterile alpha motif domain containing 8
chr12_+_112907006 0.33 ENST00000680455.1
ENST00000551241.6
ENST00000550689.2
ENST00000679841.1
ENST00000679494.1
ENST00000553185.2
2'-5'-oligoadenylate synthetase 1
chr6_-_127459364 0.33 ENST00000487331.2
ENST00000483725.8
KIAA0408
chr10_-_73096850 0.32 ENST00000307116.6
ENST00000373008.6
ENST00000394890.7
prolyl 4-hydroxylase subunit alpha 1
chr12_+_112906949 0.31 ENST00000679971.1
ENST00000675868.2
ENST00000550883.2
ENST00000553152.2
ENST00000202917.10
ENST00000679467.1
ENST00000680659.1
ENST00000540589.3
ENST00000552526.2
ENST00000681228.1
ENST00000680934.1
ENST00000681700.1
ENST00000679987.1
2'-5'-oligoadenylate synthetase 1
chr9_+_122519141 0.31 ENST00000340750.1
olfactory receptor family 1 subfamily J member 4
chr15_+_40807590 0.31 ENST00000299173.14
ENST00000566407.5
zinc finger FYVE-type containing 19
chr1_-_9069608 0.31 ENST00000377424.9
solute carrier family 2 member 5
chr10_-_73096974 0.30 ENST00000440381.5
ENST00000263556.3
prolyl 4-hydroxylase subunit alpha 1
chr16_+_71358713 0.29 ENST00000349553.9
ENST00000302628.9
ENST00000562305.5
calbindin 2
chr19_+_44751251 0.29 ENST00000444487.1
BCL3 transcription coactivator
chr12_-_75209701 0.28 ENST00000350228.6
ENST00000298972.5
potassium voltage-gated channel subfamily C member 2
chr17_+_42844573 0.28 ENST00000253799.8
ENST00000452774.2
amine oxidase copper containing 2
chr11_-_111923722 0.28 ENST00000527950.5
crystallin alpha B
chr5_+_141177790 0.28 ENST00000239444.4
ENST00000623995.1
protocadherin beta 8
novel transcript
chr12_-_75209814 0.27 ENST00000549446.6
potassium voltage-gated channel subfamily C member 2
chr12_+_112906777 0.26 ENST00000452357.7
ENST00000445409.7
2'-5'-oligoadenylate synthetase 1
chr3_+_101827982 0.26 ENST00000461724.5
ENST00000483180.5
ENST00000394054.6
NFKB inhibitor zeta
chr9_-_101383558 0.26 ENST00000674556.1
bile acid-CoA:amino acid N-acyltransferase
chr12_+_93571832 0.25 ENST00000549887.1
suppressor of cytokine signaling 2
chr8_-_22232020 0.25 ENST00000454243.7
ENST00000321613.7
phytanoyl-CoA 2-hydroxylase interacting protein
chr2_+_85695368 0.25 ENST00000526018.1
granulysin
chr12_+_93571664 0.25 ENST00000622746.4
ENST00000548537.1
suppressor of cytokine signaling 2
chr9_-_111036207 0.24 ENST00000541779.5
lysophosphatidic acid receptor 1
chr1_-_75611083 0.24 ENST00000370855.5
solute carrier family 44 member 5
chr6_+_57317602 0.23 ENST00000274891.10
ENST00000671770.1
ENST00000672107.1
ENST00000615550.5
DNA primase subunit 2
chr14_-_49688201 0.23 ENST00000553805.2
ENST00000554396.5
ENST00000216367.10
DNA polymerase epsilon 2, accessory subunit
chr7_+_30284574 0.23 ENST00000323037.5
zinc and ring finger 2
chr13_+_112979306 0.22 ENST00000421756.5
MCF.2 cell line derived transforming sequence like
chr19_-_5867741 0.22 ENST00000252675.6
fucosyltransferase 5
chr12_-_21941300 0.22 ENST00000684084.1
ATP binding cassette subfamily C member 9
chr14_-_34630124 0.22 ENST00000362031.10
ENST00000557265.6
ENST00000652385.1
sorting nexin 6
chr14_-_56816693 0.22 ENST00000673035.1
orthodenticle homeobox 2
chr19_+_18340629 0.22 ENST00000597431.2
pyroglutamyl-peptidase I
chr1_-_230978796 0.21 ENST00000522821.5
ENST00000366662.8
ENST00000366661.9
ENST00000522399.1
tetratricopeptide repeat domain 13
chr3_-_112133218 0.21 ENST00000488580.5
ENST00000308910.9
ENST00000460387.6
ENST00000484193.5
ENST00000487901.1
germinal center associated signaling and motility
chr8_+_32548267 0.21 ENST00000356819.7
neuregulin 1
chr14_-_34630109 0.20 ENST00000396526.7
sorting nexin 6
chr2_-_1744442 0.20 ENST00000433670.5
ENST00000425171.1
ENST00000252804.9
peroxidasin
chr16_+_89630263 0.20 ENST00000261615.5
dipeptidase 1
chr13_-_79405784 0.19 ENST00000267229.11
RNA binding motif protein 26
chr1_-_113905020 0.19 ENST00000432415.5
ENST00000369571.2
ENST00000256658.8
ENST00000369564.5
adaptor related protein complex 4 subunit beta 1
chr7_-_29146436 0.19 ENST00000396276.7
carboxypeptidase vitellogenic like
chr17_+_69502397 0.18 ENST00000613873.4
ENST00000589647.5
mitogen-activated protein kinase kinase 6
chr2_-_89213917 0.18 ENST00000498435.1
immunoglobulin kappa variable 1-27
chr8_-_134712962 0.18 ENST00000523399.5
ENST00000377838.8
zinc finger and AT-hook domain containing
chr7_-_22356914 0.18 ENST00000344041.10
Rap guanine nucleotide exchange factor 5
chr3_-_196211386 0.17 ENST00000296326.8
zinc finger DHHC-type palmitoyltransferase 19
chr20_-_3663399 0.17 ENST00000290417.7
ENST00000319242.8
GDNF family receptor alpha 4
chr14_+_69879408 0.17 ENST00000361956.8
ENST00000381280.4
SPARC related modular calcium binding 1
chr9_-_19033200 0.17 ENST00000380534.9
ENST00000380530.1
stabilizer of axonemal microtubules 1
chr5_-_163460048 0.17 ENST00000517501.1
NudC domain containing 2
chr8_+_11494367 0.17 ENST00000259089.9
ENST00000529894.1
BLK proto-oncogene, Src family tyrosine kinase
chr11_-_104968533 0.16 ENST00000444739.7
caspase 4
chr19_+_15082211 0.15 ENST00000641398.1
olfactory receptor family 1 subfamily I member 1
chr16_-_65121930 0.15 ENST00000566827.5
ENST00000394156.7
ENST00000268603.9
ENST00000562998.1
cadherin 11
chr5_+_132813283 0.15 ENST00000378693.4
sosondowah ankyrin repeat domain family member A
chr19_+_18340581 0.15 ENST00000604499.6
ENST00000269919.11
ENST00000595066.5
ENST00000252813.5
pyroglutamyl-peptidase I
chr2_+_172735838 0.15 ENST00000397081.8
Rap guanine nucleotide exchange factor 4
chr20_-_50115935 0.15 ENST00000340309.7
ENST00000415862.6
ENST00000371677.7
ubiquitin conjugating enzyme E2 V1
chr5_-_163460067 0.14 ENST00000302764.9
NudC domain containing 2
chr1_+_113905156 0.14 ENST00000650596.1
DNA cross-link repair 1B
chr20_+_43916142 0.14 ENST00000423191.6
ENST00000372999.5
TOX high mobility group box family member 2
chr12_-_57251169 0.14 ENST00000554578.5
ENST00000546246.2
ENST00000332782.7
ENST00000553489.1
SH3 and cysteine rich domain 3
chr17_+_51165435 0.14 ENST00000514264.6
NME/NM23 nucleoside diphosphate kinase 2
chr4_-_55592225 0.14 ENST00000295645.9
phosducin like 2
chr3_+_57060658 0.14 ENST00000334325.2
spermatogenesis associated 12
chr7_-_22357112 0.13 ENST00000405243.1
ENST00000665637.1
Rap guanine nucleotide exchange factor 5
chr19_+_6464229 0.12 ENST00000600229.6
ENST00000356762.7
crumbs cell polarity complex component 3
chr13_+_31945826 0.12 ENST00000647500.1
FRY microtubule binding protein
chr1_-_9069797 0.12 ENST00000473209.1
solute carrier family 2 member 5
chr4_+_155666963 0.12 ENST00000455639.6
guanylate cyclase 1 soluble subunit alpha 1
chr1_-_113904789 0.11 ENST00000369569.6
ENST00000369567.5
adaptor related protein complex 4 subunit beta 1
chr7_-_29146527 0.11 ENST00000265394.10
carboxypeptidase vitellogenic like
chr3_-_12841527 0.11 ENST00000396953.6
ENST00000457131.1
ENST00000435983.5
ENST00000273223.10
ENST00000429711.7
ENST00000396957.5
ribosomal protein L32
chr3_+_40477107 0.11 ENST00000314686.9
ENST00000447116.6
ENST00000429348.6
ENST00000432264.4
ENST00000456778.5
zinc finger protein 619
chr1_+_157993601 0.11 ENST00000359209.11
kirre like nephrin family adhesion molecule 1
chr1_+_12125892 0.11 ENST00000413146.6
TNF receptor superfamily member 8
chr12_+_51888217 0.10 ENST00000340970.8
ankyrin repeat domain 33
chr3_-_122993232 0.10 ENST00000650207.1
ENST00000616742.4
ENST00000393583.6
semaphorin 5B
chr11_-_45665578 0.10 ENST00000308064.7
carbohydrate sulfotransferase 1
chr14_+_76826372 0.10 ENST00000393774.7
ENST00000555189.1
leucine rich repeat containing 74A
chr12_-_21941402 0.10 ENST00000326684.8
ENST00000682068.1
ENST00000621589.2
ENST00000261200.9
ENST00000683676.1
ATP binding cassette subfamily C member 9
chr1_+_100038087 0.10 ENST00000370152.8
major facilitator superfamily domain containing 14A
chr10_+_122980448 0.10 ENST00000405485.2
phosphoseryl-tRNA kinase
chr12_+_51888083 0.10 ENST00000301190.11
ankyrin repeat domain 33
chr7_-_93574721 0.10 ENST00000426151.7
ENST00000649521.1
calcitonin receptor
chr19_-_39840671 0.10 ENST00000597224.5
fibrillarin
chr14_-_58427114 0.10 ENST00000556007.6
translocase of inner mitochondrial membrane 9
chr1_+_157993273 0.10 ENST00000360089.8
ENST00000368173.7
kirre like nephrin family adhesion molecule 1
chr12_+_1820558 0.10 ENST00000299194.6
leucine rich repeats and transmembrane domains 2
chr19_+_9178979 0.09 ENST00000642043.1
ENST00000641288.2
olfactory receptor family 7 subfamily D member 2
chr19_+_17215716 0.09 ENST00000593597.1
unconventional SNARE in the ER 1
chr11_-_102705737 0.09 ENST00000260229.5
matrix metallopeptidase 27
chr12_+_53295506 0.09 ENST00000549759.2
ENST00000628881.2
ENST00000351500.7
ENST00000550846.5
ENST00000334478.9
ENST00000547130.6
ENST00000552742.6
prefoldin subunit 5
chr11_+_64291285 0.08 ENST00000422670.7
ENST00000538767.1
potassium two pore domain channel subfamily K member 4
chrX_-_21658324 0.08 ENST00000379499.3
kelch like family member 34
chr6_-_62286161 0.08 ENST00000281156.5
KH RNA binding domain containing, signal transduction associated 2
chr3_+_89107613 0.08 ENST00000336596.7
EPH receptor A3
chr17_+_38297023 0.08 ENST00000619548.1
ENST00000613675.5
mitochondrial ribosomal protein L45
chr12_+_1820255 0.08 ENST00000543818.5
leucine rich repeats and transmembrane domains 2
chr4_-_88823306 0.08 ENST00000395002.6
family with sequence similarity 13 member A
chr4_+_155666718 0.07 ENST00000621234.4
ENST00000511108.5
guanylate cyclase 1 soluble subunit alpha 1
chrX_-_11665908 0.07 ENST00000337414.9
Rho GTPase activating protein 6
chr14_-_58427158 0.07 ENST00000555097.1
ENST00000556367.6
ENST00000555404.5
translocase of inner mitochondrial membrane 9
chr19_+_6464491 0.07 ENST00000308243.7
crumbs cell polarity complex component 3
chr3_-_169869833 0.07 ENST00000523069.1
ENST00000264676.9
ENST00000316428.10
leucine rich repeat containing 31
chr4_-_88823165 0.06 ENST00000508369.5
family with sequence similarity 13 member A
chr4_+_20700436 0.06 ENST00000444671.6
ENST00000510700.5
ENST00000506745.5
ENST00000514663.5
ENST00000509469.5
ENST00000515339.5
ENST00000513861.5
ENST00000502374.5
ENST00000503585.6
ENST00000511160.5
ENST00000504630.5
ENST00000513590.5
ENST00000514292.5
ENST00000502938.5
ENST00000509625.1
ENST00000505160.1
ENST00000507634.5
ENST00000513459.5
ENST00000511089.1
parkin coregulated like
chr11_-_207221 0.06 ENST00000486280.1
ENST00000332865.10
ENST00000529614.6
ENST00000325147.13
ENST00000410108.5
ENST00000382762.7
Bet1 golgi vesicular membrane trafficking protein like
chr19_+_54573781 0.06 ENST00000391738.8
ENST00000251376.7
ENST00000391737.3
ENST00000629481.1
leukocyte immunoglobulin like receptor A2
chr2_+_218880844 0.06 ENST00000258411.8
Wnt family member 10A
chr6_-_2962097 0.06 ENST00000380524.5
serpin family B member 6
chr21_-_44592505 0.06 ENST00000400368.1
keratin associated protein 10-6
chr11_-_89876017 0.06 ENST00000329862.6
tripartite motif containing 64B
chr22_+_24603147 0.05 ENST00000412658.5
ENST00000445029.5
ENST00000400382.6
ENST00000419133.5
ENST00000438643.6
ENST00000452551.5
ENST00000412898.5
ENST00000400380.5
ENST00000455483.5
ENST00000430289.5
gamma-glutamyltransferase 1
chr11_-_1608463 0.05 ENST00000399685.1
keratin associated protein 5-3
chr16_-_46689145 0.05 ENST00000299138.12
VPS35 retromer complex component
chr4_-_88823214 0.05 ENST00000513837.5
ENST00000503556.5
family with sequence similarity 13 member A
chr7_-_37916807 0.05 ENST00000436072.7
secreted frizzled related protein 4
chr1_-_9069572 0.05 ENST00000377414.7
solute carrier family 2 member 5
chr3_-_52834901 0.04 ENST00000486659.5
musculoskeletal, embryonic nuclear protein 1
chr3_+_167735704 0.04 ENST00000446050.7
ENST00000295777.9
ENST00000472747.2
serpin family I member 1
chr2_-_86195400 0.04 ENST00000442664.6
ENST00000409051.6
ENST00000410111.8
ENST00000620815.4
ENST00000449247.6
inner membrane mitochondrial protein
chr1_-_45491150 0.04 ENST00000372086.4
testis associated actin remodelling kinase 2
chr9_-_33025088 0.04 ENST00000436040.7
aprataxin
chr11_-_624924 0.04 ENST00000358353.8
ENST00000397542.7
ENST00000526077.5
ENST00000534311.1
ENST00000531088.5
cadherin related family member 5
chr1_-_158331522 0.03 ENST00000368168.4
CD1b molecule
chr3_-_52835011 0.03 ENST00000446157.3
musculoskeletal, embryonic nuclear protein 1
chr16_-_1954682 0.03 ENST00000268661.8
ribosomal protein L3 like
chr2_-_70768175 0.03 ENST00000355733.7
ENST00000447731.6
ENST00000430656.5
ENST00000264436.9
ENST00000413157.6
adducin 2
chr6_-_41747390 0.03 ENST00000356667.8
ENST00000373025.7
ENST00000425343.6
progastricsin
chr9_-_33025052 0.03 ENST00000673248.1
aprataxin
chr15_+_79311084 0.03 ENST00000299705.10
transmembrane p24 trafficking protein 3
chr6_-_159045104 0.03 ENST00000326965.7
T cell activation RhoGTPase activating protein
chr15_-_72231113 0.03 ENST00000565154.6
ENST00000565184.6
ENST00000335181.10
pyruvate kinase M1/2
chr11_+_8683201 0.02 ENST00000526562.5
ENST00000525981.1
ribosomal protein L27a
chr4_+_155666827 0.02 ENST00000511507.5
ENST00000506455.6
guanylate cyclase 1 soluble subunit alpha 1
chr17_+_41105332 0.02 ENST00000391415.1
ENST00000617453.1
keratin associated protein 4-9
chr2_+_96760857 0.02 ENST00000377075.3
cyclin and CBS domain divalent metal cation transport mediator 4
chr1_-_44141631 0.02 ENST00000634670.1
Kruppel like factor 18
chr1_+_200739542 0.02 ENST00000358823.6
calmodulin regulated spectrin associated protein family member 2
chrX_-_44542833 0.02 ENST00000378045.5
FUN14 domain containing 1
chr8_-_98294339 0.01 ENST00000341166.3
NIPA like domain containing 2
chr17_-_44066595 0.01 ENST00000585388.2
ENST00000293406.8
LSM12 homolog
chr9_-_135961310 0.01 ENST00000371756.4
UBA domain containing 1
chr10_+_48684859 0.01 ENST00000360890.6
ENST00000325239.11
WDFY family member 4
chr7_-_88795732 0.01 ENST00000297203.3
testis expressed 47
chrX_+_155881306 0.00 ENST00000286448.12
ENST00000262640.11
ENST00000460621.6
vesicle associated membrane protein 7
chr3_+_35679690 0.00 ENST00000413378.5
ENST00000417925.5
cAMP regulated phosphoprotein 21

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.2 0.5 GO:1902728 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.2 0.8 GO:0030035 microspike assembly(GO:0030035)
0.2 0.5 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.1 0.6 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1 3.7 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.1 0.4 GO:0032827 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.1 0.6 GO:0042851 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.1 0.3 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.1 1.2 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.7 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.1 0.3 GO:0002818 intracellular defense response(GO:0002818)
0.1 0.5 GO:0015755 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.1 0.2 GO:0016999 antibiotic metabolic process(GO:0016999)
0.1 2.0 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.4 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.1 0.1 GO:1903179 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
0.1 0.6 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.3 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.2 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.2 GO:0009631 cold acclimation(GO:0009631)
0.0 0.7 GO:0015871 choline transport(GO:0015871)
0.0 0.6 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0045554 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.0 0.1 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0034963 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.1 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 0.1 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.0 0.4 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.4 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.5 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.3 GO:0019530 taurine metabolic process(GO:0019530)
0.0 0.1 GO:0031627 telomeric loop formation(GO:0031627)
0.0 0.2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.3 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 1.3 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 1.7 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 0.2 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.0 0.2 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.2 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.0 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.0 0.2 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.0 0.7 GO:0033260 nuclear DNA replication(GO:0033260)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.2 3.7 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.6 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.1 0.3 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.5 GO:0097422 tubular endosome(GO:0097422)
0.1 2.1 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 0.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 1.7 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0072557 IPAF inflammasome complex(GO:0072557) AIM2 inflammasome complex(GO:0097169)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 1.3 GO:0001772 immunological synapse(GO:0001772)
0.0 0.3 GO:0097512 cardiac myofibril(GO:0097512)
0.0 1.5 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.2 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.9 GO:0031904 endosome lumen(GO:0031904)
0.0 0.1 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 1.6 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.7 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.2 0.6 GO:0047635 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.1 0.4 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.6 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.6 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 0.4 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 0.3 GO:0052816 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
0.1 0.3 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.3 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.5 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.1 0.5 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 0.5 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.7 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.3 GO:0052596 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 1.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.5 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.6 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.2 GO:0003896 DNA primase activity(GO:0003896)
0.0 1.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.2 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.2 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 2.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.1 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.1 GO:0097604 temperature-gated cation channel activity(GO:0097604)
0.0 0.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.5 GO:0016918 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.0 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
0.0 0.4 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0004673 protein histidine kinase activity(GO:0004673)
0.0 0.4 GO:0008242 omega peptidase activity(GO:0008242)
0.0 2.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 1.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 3.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 3.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 2.1 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.2 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 1.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.5 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling