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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for RARA

Z-value: 0.83

Motif logo

Transcription factors associated with RARA

Gene Symbol Gene ID Gene Info
ENSG00000131759.18 RARA

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RARAhg38_v1_chr17_+_40318237_40318299-0.402.6e-02Click!

Activity profile of RARA motif

Sorted Z-values of RARA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RARA

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_205579531 3.79 ENST00000616173.4
ENST00000536357.2
ENST00000621216.1
major facilitator superfamily domain containing 4A
chr3_+_13549117 3.50 ENST00000404922.8
fibulin 2
chr14_-_106622837 3.43 ENST00000390628.3
immunoglobulin heavy variable 1-58
chr3_+_13549136 3.41 ENST00000295760.11
fibulin 2
chr10_-_13099652 2.57 ENST00000378839.1
coiled-coil domain containing 3
chr16_-_52547113 2.46 ENST00000219746.14
TOX high mobility group box family member 3
chr6_+_32741382 1.86 ENST00000374940.4
major histocompatibility complex, class II, DQ alpha 2
chr12_+_101697621 1.72 ENST00000229266.8
ENST00000549872.5
choline phosphotransferase 1
chr19_+_7669080 1.67 ENST00000629642.1
resistin
chrX_+_153072454 1.52 ENST00000421798.5
PNMA family member 6A
chr17_+_14301069 1.46 ENST00000360954.3
heparan sulfate-glucosamine 3-sulfotransferase 3B1
chr19_-_6720641 1.37 ENST00000245907.11
complement C3
chr18_+_46946821 1.28 ENST00000245121.9
ENST00000356157.12
katanin catalytic subunit A1 like 2
chrX_-_8732116 1.26 ENST00000262648.8
anosmin 1
chr1_+_18480930 1.12 ENST00000400664.3
kelch domain containing 7A
chr10_-_133373332 1.10 ENST00000368547.4
enoyl-CoA hydratase, short chain 1
chr1_+_113390495 1.07 ENST00000307546.14
membrane associated guanylate kinase, WW and PDZ domain containing 3
chr2_+_106065678 1.03 ENST00000238044.8
ENST00000437659.1
ECRG4 augurin precursor
chr5_-_16508788 1.00 ENST00000682142.1
reticulophagy regulator 1
chr2_+_222424520 0.97 ENST00000321276.8
sphingosine-1-phosphate phosphatase 2
chr5_-_16508990 0.95 ENST00000399793.6
reticulophagy regulator 1
chr20_+_44531817 0.95 ENST00000372889.5
ENST00000372887.5
cAMP-dependent protein kinase inhibitor gamma
chr19_+_34677723 0.90 ENST00000505365.2
zinc finger protein 302
chr22_+_23145366 0.90 ENST00000341989.9
ENST00000263116.8
RAB36, member RAS oncogene family
chr10_+_92848461 0.89 ENST00000443748.6
ENST00000371543.5
ENST00000260762.10
exocyst complex component 6
chr12_-_121669646 0.88 ENST00000355329.7
MORN repeat containing 3
chr19_+_34677639 0.86 ENST00000627982.2
ENST00000613363.4
ENST00000502743.5
ENST00000509528.5
ENST00000506901.5
ENST00000457781.6
ENST00000505163.5
ENST00000505242.6
ENST00000423823.6
ENST00000507959.5
ENST00000446502.6
zinc finger protein 302
chr17_-_4560564 0.85 ENST00000574584.1
ENST00000381550.8
ENST00000301395.7
gamma-glutamyltransferase 6
chr19_-_821929 0.82 ENST00000359894.6
ENST00000520876.8
ENST00000519502.2
phospholipid phosphatase related 3
chr11_+_63369779 0.82 ENST00000279178.4
solute carrier family 22 member 9
chr1_+_3690654 0.79 ENST00000378285.5
ENST00000378280.5
ENST00000378288.8
tumor protein p73
chr1_-_39901996 0.79 ENST00000397332.2
MYCL proto-oncogene, bHLH transcription factor
chr6_+_29942523 0.76 ENST00000376809.10
ENST00000376802.2
ENST00000638375.1
major histocompatibility complex, class I, A
chr11_-_8964927 0.74 ENST00000525069.5
TMEM9 domain family member B
chr9_-_21994345 0.73 ENST00000579755.2
ENST00000530628.2
cyclin dependent kinase inhibitor 2A
chr11_-_8964380 0.73 ENST00000528117.5
ENST00000309134.9
ENST00000534025.6
TMEM9 domain family member B
chr19_+_40799155 0.72 ENST00000303961.9
egl-9 family hypoxia inducible factor 2
chr3_-_112499457 0.72 ENST00000334529.10
B and T lymphocyte associated
chr1_-_108661055 0.72 ENST00000370031.5
ENST00000651461.1
ENST00000402983.5
ENST00000420055.1
HEN methyltransferase 1
chr17_+_80101562 0.71 ENST00000302262.8
ENST00000577106.5
ENST00000390015.7
alpha glucosidase
chr16_+_71626175 0.71 ENST00000268485.8
ENST00000565261.1
ENST00000299952.4
MARVEL domain containing 3
chr7_+_150368189 0.71 ENST00000519397.1
ENST00000479668.5
replication initiator 1
chr1_-_48472166 0.70 ENST00000371847.8
ENST00000396199.7
spermatogenesis associated 6
chr2_-_219245465 0.70 ENST00000392089.6
galactosidase beta 1 like
chr8_+_27491125 0.70 ENST00000517536.5
ENST00000521400.6
ENST00000521780.5
ENST00000380476.7
ENST00000518379.5
ENST00000521684.1
epoxide hydrolase 2
chr4_-_25862979 0.69 ENST00000399878.8
SEL1L family member 3
chr5_-_55994945 0.68 ENST00000381298.7
ENST00000502326.7
interleukin 6 signal transducer
chr2_-_159798234 0.67 ENST00000429078.6
ENST00000553424.5
CD302 molecule
chr9_-_137114678 0.67 ENST00000497375.1
ENST00000371579.7
dipeptidyl peptidase 7
chr3_-_52452828 0.67 ENST00000496590.1
troponin C1, slow skeletal and cardiac type
chr16_+_2969307 0.67 ENST00000576565.1
ENST00000318782.9
progestin and adipoQ receptor family member 4
chr16_+_2969270 0.67 ENST00000293978.12
progestin and adipoQ receptor family member 4
chr15_-_65422894 0.66 ENST00000352385.3
immunoglobulin superfamily DCC subclass member 4
chr16_+_2969548 0.65 ENST00000572687.1
progestin and adipoQ receptor family member 4
chr9_+_129036614 0.65 ENST00000684074.1
mitoguardin 2
chr22_+_44677077 0.65 ENST00000403581.5
proline rich 5
chr22_+_44677044 0.64 ENST00000006251.11
proline rich 5
chr17_+_74432079 0.63 ENST00000392627.7
ENST00000392628.7
ENST00000582473.2
G protein-coupled receptor class C group 5 member C
chr19_-_55461597 0.62 ENST00000589080.1
ENST00000425675.7
ENST00000085068.7
isochorismatase domain containing 2
chr17_-_11997372 0.61 ENST00000322748.7
ENST00000454073.7
ENST00000580306.7
ENST00000580903.1
zinc finger protein 18
chr12_+_104064520 0.61 ENST00000229330.9
host cell factor C2
chr19_+_17302854 0.60 ENST00000594999.1
mitochondrial ribosomal protein L34
chr3_+_43690928 0.60 ENST00000644371.2
abhydrolase domain containing 5, lysophosphatidic acid acyltransferase
chr5_-_135954962 0.60 ENST00000522943.5
ENST00000514447.2
ENST00000274507.6
leukocyte cell derived chemotaxin 2
chrX_+_51743395 0.59 ENST00000340438.6
G1 to S phase transition 2
chr1_+_222618075 0.58 ENST00000344922.10
MIA SH3 domain ER export factor 3
chr4_-_48080172 0.58 ENST00000507351.1
TXK tyrosine kinase
chr1_+_160151597 0.58 ENST00000368081.9
ATPase Na+/K+ transporting subunit alpha 4
chr9_-_127916978 0.58 ENST00000361444.3
ENST00000335791.10
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr16_+_71626149 0.57 ENST00000567566.1
MARVEL domain containing 3
chr20_+_44531758 0.57 ENST00000372891.7
ENST00000372892.7
ENST00000372894.7
cAMP-dependent protein kinase inhibitor gamma
chr14_-_21025490 0.56 ENST00000553442.5
ENST00000555869.5
ENST00000556457.5
ENST00000397844.6
ENST00000554415.5
ENST00000556974.5
ENST00000554419.5
ENST00000298687.9
ENST00000397858.5
ENST00000360463.7
ENST00000350792.7
ENST00000397847.6
NDRG family member 2
chr1_-_18859682 0.56 ENST00000375371.3
taste 1 receptor member 2
chr1_-_160098593 0.55 ENST00000314485.12
immunoglobulin superfamily member 8
chr4_+_158672237 0.55 ENST00000682734.1
electron transfer flavoprotein dehydrogenase
chr9_-_33264559 0.55 ENST00000473781.1
ENST00000379704.7
ENST00000488499.1
BAG cochaperone 1
chr1_-_154956086 0.55 ENST00000368463.8
ENST00000368460.7
ENST00000368465.5
PBX homeobox interacting protein 1
chrX_-_100731504 0.55 ENST00000372989.5
ENST00000276141.10
synaptotagmin like 4
chr9_+_136886490 0.53 ENST00000247668.7
TNF receptor associated factor 2
chr14_-_89619118 0.53 ENST00000345097.8
ENST00000555855.5
ENST00000555353.5
forkhead box N3
chr19_+_827823 0.53 ENST00000233997.4
azurocidin 1
chr19_-_4581755 0.53 ENST00000676793.1
semaphorin 6B
chr2_-_174487005 0.52 ENST00000392552.7
ENST00000295500.8
ENST00000614352.4
ENST00000392551.6
G protein-coupled receptor 155
chr2_+_188292771 0.52 ENST00000359135.7
GULP PTB domain containing engulfment adaptor 1
chr6_-_145964330 0.52 ENST00000275233.12
ENST00000367505.6
SNF2 histone linker PHD RING helicase
chr22_+_44676808 0.51 ENST00000624862.3
proline rich 5
chr6_-_145964084 0.51 ENST00000438092.6
ENST00000629427.2
SNF2 histone linker PHD RING helicase
chr1_+_222815065 0.50 ENST00000675039.1
ENST00000675961.1
dispatched RND transporter family member 1
chr22_-_24245059 0.50 ENST00000398292.3
ENST00000263112.11
ENST00000327365.10
ENST00000424217.1
gamma-glutamyltransferase 5
chr19_-_49423441 0.50 ENST00000270631.2
parathyroid hormone 2
chr1_+_222815021 0.49 ENST00000675850.1
ENST00000495684.2
dispatched RND transporter family member 1
chr7_+_150368790 0.49 ENST00000397281.6
ENST00000444957.3
ENST00000466559.1
ENST00000475514.5
ENST00000482680.1
ENST00000488943.1
ENST00000489432.7
ENST00000518514.1
ENST00000478789.5
replication initiator 1
zinc finger protein 775
chr9_-_122264798 0.49 ENST00000417201.4
RNA binding motif protein 18
chrX_+_11111291 0.48 ENST00000321143.8
ENST00000380762.5
ENST00000380763.7
holocytochrome c synthase
chr10_+_113679159 0.48 ENST00000621345.4
ENST00000429617.5
ENST00000369331.8
caspase 7
chr12_+_121712740 0.47 ENST00000449592.7
transmembrane protein 120B
chr15_-_26773022 0.47 ENST00000311550.10
ENST00000622697.4
gamma-aminobutyric acid type A receptor subunit beta3
chr17_-_63446260 0.47 ENST00000448884.6
ENST00000582297.5
ENST00000360793.8
ENST00000582034.5
ENST00000578072.1
cytochrome b561
chr1_-_48472007 0.47 ENST00000371843.7
spermatogenesis associated 6
chr22_-_29267965 0.47 ENST00000216085.12
rhomboid domain containing 3
chr4_+_1793776 0.47 ENST00000352904.6
fibroblast growth factor receptor 3
chr15_+_32718476 0.46 ENST00000652365.1
gremlin 1, DAN family BMP antagonist
chr16_-_57186053 0.46 ENST00000565760.5
ENST00000570184.1
ENST00000562324.5
proteasome activator subunit 3 interacting protein 1
chr11_-_17389323 0.46 ENST00000528731.1
potassium inwardly rectifying channel subfamily J member 11
chr9_-_83817632 0.45 ENST00000376365.7
ENST00000376371.7
G kinase anchoring protein 1
chr22_+_25069819 0.45 ENST00000401395.1
KIAA1671
chr18_-_57803307 0.45 ENST00000648908.2
ATPase phospholipid transporting 8B1
chr19_-_4540028 0.45 ENST00000306390.7
leucine rich alpha-2-glycoprotein 1
chrX_+_55717796 0.44 ENST00000262850.7
Ras related GTP binding B
chr16_+_641792 0.44 ENST00000307650.9
ENST00000629534.2
MAPK regulated corepressor interacting protein 2
chr8_+_74320832 0.44 ENST00000676377.1
ganglioside induced differentiation associated protein 1
chr5_-_157859096 0.42 ENST00000530742.5
ENST00000523908.5
ENST00000523094.5
ENST00000411809.7
clathrin interactor 1
chr4_+_158672266 0.42 ENST00000684622.1
ENST00000683483.1
ENST00000684641.1
ENST00000682456.1
ENST00000684627.1
ENST00000511912.6
ENST00000684505.1
ENST00000683305.1
ENST00000684036.1
ENST00000683751.1
ENST00000684129.1
ENST00000307738.5
electron transfer flavoprotein dehydrogenase
chr1_-_145995713 0.42 ENST00000425134.2
thioredoxin interacting protein
chr15_+_32717994 0.42 ENST00000560677.5
ENST00000560830.1
ENST00000651154.1
gremlin 1, DAN family BMP antagonist
chr5_+_102754631 0.42 ENST00000510208.2
peptidylglycine alpha-amidating monooxygenase
chr5_+_140639419 0.42 ENST00000513002.5
ENST00000394671.8
transmembrane and coiled-coil domains 6
chr14_+_54509885 0.42 ENST00000557317.1
ENST00000216420.12
cell growth regulator with ring finger domain 1
chr9_+_121268060 0.41 ENST00000373808.8
ENST00000432226.7
ENST00000449733.7
gelsolin
chr2_+_98087160 0.41 ENST00000477737.6
von Willebrand factor A domain containing 3B
chr16_-_57185808 0.41 ENST00000562406.5
ENST00000568671.5
ENST00000567044.5
proteasome activator subunit 3 interacting protein 1
chr20_-_35278088 0.41 ENST00000456790.2
ENST00000424358.1
MMP24 opposite strand
chr8_+_74320613 0.40 ENST00000675821.1
ganglioside induced differentiation associated protein 1
chr19_-_12881460 0.40 ENST00000592506.1
deoxyribonuclease 2, lysosomal
chr16_+_56328661 0.40 ENST00000562316.6
G protein subunit alpha o1
chr2_-_70994809 0.40 ENST00000272438.9
testis expressed 261
chrX_+_55717733 0.39 ENST00000414239.5
ENST00000374941.9
Ras related GTP binding B
chr16_+_69951180 0.39 ENST00000288040.10
ENST00000449317.6
C-type lectin domain family 18 member A
chr11_-_130314575 0.39 ENST00000397753.5
zinc finger and BTB domain containing 44
chr8_-_100336184 0.39 ENST00000519527.5
ENST00000522369.5
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr1_+_43389889 0.38 ENST00000562955.2
ENST00000634258.3
SZT2 subunit of KICSTOR complex
chr17_+_75110021 0.37 ENST00000584947.1
armadillo repeat containing 7
chr11_+_64241600 0.37 ENST00000535135.7
ENST00000652094.1
FKBP prolyl isomerase 2
chr19_-_7699466 0.37 ENST00000360067.8
Fc fragment of IgE receptor II
chr2_+_227616998 0.37 ENST00000641801.1
small cysteine and glycine repeat containing 4
chr1_+_45500287 0.37 ENST00000401061.9
ENST00000616135.1
metabolism of cobalamin associated C
chr3_-_11582330 0.37 ENST00000451674.6
vestigial like family member 4
chr2_-_112433519 0.37 ENST00000496537.1
ENST00000330575.9
ENST00000302558.8
RANBP2 like and GRIP domain containing 8
chr16_-_16223467 0.37 ENST00000575728.1
ENST00000574094.6
ENST00000205557.12
ATP binding cassette subfamily C member 6
chr15_+_72118392 0.37 ENST00000340912.6
SUMO peptidase family member, NEDD8 specific
chr13_-_20525796 0.37 ENST00000298248.12
ENST00000382812.5
ENST00000644593.1
ENST00000643750.1
crystallin lambda 1
chr12_+_111766887 0.36 ENST00000416293.7
ENST00000261733.7
aldehyde dehydrogenase 2 family member
chr2_+_188292814 0.36 ENST00000409580.5
ENST00000409637.7
GULP PTB domain containing engulfment adaptor 1
chrX_-_20141810 0.34 ENST00000379593.1
ENST00000379607.10
eukaryotic translation initiation factor 1A X-linked
chr7_+_90245167 0.34 ENST00000389297.8
cilia and flagella associated protein 69
chr15_-_45201094 0.34 ENST00000561278.1
ENST00000290894.12
Src homology 2 domain containing F
chr16_+_70173783 0.33 ENST00000541793.7
ENST00000314151.12
ENST00000565806.5
ENST00000569347.6
ENST00000536907.2
C-type lectin domain family 18 member C
chr7_+_90245207 0.33 ENST00000497910.5
cilia and flagella associated protein 69
chr19_-_7488966 0.33 ENST00000593547.1
peroxisomal biogenesis factor 11 gamma
chr9_-_33264678 0.33 ENST00000635077.1
ENST00000634734.3
BAG cochaperone 1
chr7_+_56064224 0.33 ENST00000651354.1
ENST00000651586.1
ENST00000652303.1
ENST00000275607.13
ENST00000650735.1
ENST00000395435.7
ENST00000413952.7
ENST00000342190.11
ENST00000437307.6
ENST00000434526.8
ENST00000413756.5
ENST00000451338.1
sulfatase modifying factor 2
chr2_-_218568291 0.33 ENST00000418019.5
ENST00000454775.5
ENST00000338465.5
ENST00000415516.5
ENST00000258399.8
ubiquitin specific peptidase 37
chr3_+_45026296 0.33 ENST00000296130.5
C-type lectin domain family 3 member B
chr19_+_53521245 0.33 ENST00000649326.1
zinc finger protein 331
chr15_-_100544243 0.32 ENST00000538112.6
ENST00000559639.1
ENST00000558884.6
ceramide synthase 3
chr1_-_39901861 0.32 ENST00000372816.3
ENST00000372815.1
MYCL proto-oncogene, bHLH transcription factor
chr6_+_35259703 0.32 ENST00000373953.8
ENST00000339411.5
zinc finger protein 76
chr9_+_137665916 0.32 ENST00000636027.1
euchromatic histone lysine methyltransferase 1
chr4_-_106316181 0.32 ENST00000394706.7
ENST00000394708.7
TBC1 domain containing kinase
chr4_-_106316216 0.32 ENST00000361687.8
ENST00000507696.1
ENST00000509532.5
TBC1 domain containing kinase
chr11_+_118531183 0.31 ENST00000528373.5
ENST00000313236.10
ENST00000354284.8
ENST00000533137.5
ENST00000532762.5
ENST00000526973.5
ENST00000354064.11
ENST00000533102.5
ENST00000527267.1
ENST00000524725.5
ENST00000533689.1
transmembrane protein 25
chr16_+_71845958 0.31 ENST00000427980.7
ENST00000568581.5
ataxin 1 like
IST1 factor associated with ESCRT-III
chr1_-_204494752 0.31 ENST00000684373.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
chr3_-_55487295 0.31 ENST00000264634.9
Wnt family member 5A
chr1_-_58700052 0.31 ENST00000472487.6
ENST00000655340.1
Myb like, SWIRM and MPN domains 1
chr20_-_35742207 0.31 ENST00000397370.3
ENST00000528062.7
ENST00000374038.7
ENST00000253363.11
ENST00000361162.10
RNA binding motif protein 39
chr14_-_37595224 0.31 ENST00000250448.5
forkhead box A1
chr16_+_1313995 0.31 ENST00000402301.5
ubiquitin conjugating enzyme E2 I
chr9_+_111631300 0.31 ENST00000313525.4
DnaJ heat shock protein family (Hsp40) member C25
chr11_-_75525925 0.31 ENST00000336898.8
glycerophosphodiester phosphodiesterase domain containing 5
chr8_+_116938180 0.30 ENST00000378279.4
alanine and arginine rich domain containing protein
chr9_+_122510802 0.30 ENST00000335302.5
olfactory receptor family 1 subfamily J member 2
chr19_-_12484773 0.30 ENST00000397732.8
zinc finger protein 709
chr2_+_100562941 0.30 ENST00000264254.11
phosducin like 3
chr9_-_137200732 0.29 ENST00000409012.6
taperin
chr2_+_96537254 0.29 ENST00000454558.2
AT-rich interaction domain 5A
chr5_-_16508858 0.29 ENST00000684456.1
reticulophagy regulator 1
chr19_-_19033480 0.29 ENST00000452918.7
ENST00000600377.1
ENST00000337018.10
SURP and G-patch domain containing 2
chr13_-_100674813 0.29 ENST00000376234.7
ENST00000423847.1
transmembrane O-mannosyltransferase targeting cadherins 4
chr9_+_137788758 0.29 ENST00000493484.5
euchromatic histone lysine methyltransferase 1
chr17_+_6651745 0.29 ENST00000542475.3
chromosome 17 open reading frame 100
chr11_-_88337722 0.29 ENST00000677976.1
ENST00000528020.2
ENST00000393301.5
ENST00000529974.2
ENST00000227266.10
ENST00000678464.1
ENST00000679199.1
ENST00000527018.6
ENST00000679224.1
ENST00000678506.1
ENST00000678915.1
ENST00000524463.6
cathepsin C
chr19_-_39540144 0.29 ENST00000390658.4
EP300 interacting inhibitor of differentiation 2
chr19_-_7489003 0.29 ENST00000221480.6
peroxisomal biogenesis factor 11 gamma
chr19_+_36851645 0.29 ENST00000331800.8
ENST00000612719.4
ENST00000586646.1
zinc finger protein 345
chr5_+_31532277 0.28 ENST00000507818.6
ENST00000325366.14
chromosome 5 open reading frame 22
chr1_-_43389768 0.28 ENST00000372455.4
ENST00000372457.9
ENST00000290663.10
mediator complex subunit 8
chr3_-_127736329 0.28 ENST00000398101.7
monoglyceride lipase
chr17_-_37609361 0.28 ENST00000614941.4
ENST00000619541.4
ENST00000622045.4
ENST00000616179.4
ENST00000621136.4
ENST00000612223.5
ENST00000620424.1
synergin gamma
chr16_+_70114306 0.28 ENST00000288050.9
ENST00000398122.7
ENST00000568530.5
pyruvate dehydrogenase phosphatase regulatory subunit
chr11_+_66257696 0.27 ENST00000421552.5
ENST00000394067.7
ENST00000316924.9
ENST00000394078.5
kinesin light chain 2
chr10_-_13300051 0.27 ENST00000479604.1
ENST00000263038.9
phytanoyl-CoA 2-hydroxylase
chr2_+_238060924 0.27 ENST00000651534.1
ENST00000413463.6
ENST00000254663.12
ENST00000409736.6
ENST00000412508.6
selenocysteine lyase
chr17_-_63446168 0.27 ENST00000584031.5
ENST00000392976.5
cytochrome b561
chr11_+_118530990 0.27 ENST00000411589.6
ENST00000359862.8
ENST00000442938.6
transmembrane protein 25
chr15_-_51971740 0.27 ENST00000315141.5
ENST00000299601.10
LEO1 homolog, Paf1/RNA polymerase II complex component
chr9_-_76394372 0.27 ENST00000376736.6
riboflavin kinase
chr8_-_96261579 0.27 ENST00000517720.1
ENST00000523821.5
ENST00000287025.4
mitochondrial transcription termination factor 3
chr12_-_15882261 0.27 ENST00000646918.1
ENST00000647087.1
ENST00000535752.5
epidermal growth factor receptor pathway substrate 8
chr1_+_26111139 0.27 ENST00000619836.4
ENST00000444713.5
PDLIM1 interacting kinase 1 like

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0002086 diaphragm contraction(GO:0002086)
0.5 1.4 GO:0001796 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
0.4 1.7 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.4 1.7 GO:2000196 positive regulation of female gonad development(GO:2000196)
0.3 2.7 GO:0061709 reticulophagy(GO:0061709)
0.3 1.0 GO:0035638 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.3 0.9 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.3 1.5 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2 0.7 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.2 0.6 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.2 0.6 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.2 0.5 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720)
0.2 0.5 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
0.2 0.3 GO:0003213 cardiac right atrium morphogenesis(GO:0003213)
0.1 1.1 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 0.1 GO:1902957 regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956) negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.1 0.5 GO:0030576 Cajal body organization(GO:0030576)
0.1 0.5 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.2 GO:0031393 negative regulation of prostaglandin biosynthetic process(GO:0031393)
0.1 0.7 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 1.8 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.4 GO:0018032 protein amidation(GO:0018032)
0.1 0.3 GO:0060738 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528) epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.1 0.9 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.1 0.3 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.1 0.3 GO:1903937 response to acrylamide(GO:1903937)
0.1 3.9 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 0.6 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 1.2 GO:1902414 protein localization to cell junction(GO:1902414)
0.1 0.8 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.6 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.1 2.6 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.1 1.5 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 1.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.4 GO:0044858 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) renal protein absorption(GO:0097017) regulation of plasma membrane raft polarization(GO:1903906)
0.1 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.6 GO:0044375 regulation of peroxisome size(GO:0044375)
0.1 0.3 GO:1903755 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.1 0.8 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 0.2 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1 0.8 GO:0015747 urate transport(GO:0015747)
0.1 0.1 GO:0003192 mitral valve formation(GO:0003192)
0.1 0.3 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.3 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.1 0.3 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.1 0.2 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.1 0.4 GO:0051167 glucuronate catabolic process(GO:0006064) glucuronate catabolic process to xylulose 5-phosphate(GO:0019640) xylulose 5-phosphate metabolic process(GO:0051167) xylulose 5-phosphate biosynthetic process(GO:1901159)
0.1 1.0 GO:0006670 sphingosine metabolic process(GO:0006670)
0.1 0.5 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 0.2 GO:0051463 negative regulation of cortisol secretion(GO:0051463)
0.1 0.7 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.7 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.8 GO:0060992 response to fungicide(GO:0060992)
0.1 0.3 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 0.5 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.1 0.2 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 0.3 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.4 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.3 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.1 0.2 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.1 0.5 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 1.0 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.2 GO:0072144 glomerular mesangial cell development(GO:0072144)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.8 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 3.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.3 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.3 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.8 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.2 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.3 GO:0009838 abscission(GO:0009838)
0.0 0.2 GO:0035441 cell migration involved in vasculogenesis(GO:0035441) histone H3-K36 dimethylation(GO:0097676)
0.0 0.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.2 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.7 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.0 0.2 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.2 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.0 0.5 GO:0071316 cellular response to nicotine(GO:0071316)
0.0 0.1 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.2 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.6 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 6.4 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 1.2 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.6 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 0.3 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.3 GO:0033578 protein glycosylation in Golgi(GO:0033578)
0.0 0.4 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:0036245 cellular response to menadione(GO:0036245)
0.0 0.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.5 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.3 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.3 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.5 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.2 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.4 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.3 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.5 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.2 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.5 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.1 GO:0009624 response to nematode(GO:0009624)
0.0 0.6 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.2 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.4 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.1 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.5 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:1902612 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.0 0.1 GO:0009085 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.0 1.0 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.3 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.9 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.9 GO:0017004 cytochrome complex assembly(GO:0017004)
0.0 1.5 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.4 GO:0002347 response to tumor cell(GO:0002347)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 2.3 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.1 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.0 0.1 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.6 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.3 GO:0051712 positive regulation of killing of cells of other organism(GO:0051712)
0.0 0.5 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.9 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.1 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.0 0.0 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.3 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.1 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.0 0.1 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.1 GO:0097052 L-kynurenine metabolic process(GO:0097052)
0.0 0.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.7 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.4 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.0 GO:0036090 cleavage furrow ingression(GO:0036090)
0.0 0.4 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.2 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.1 GO:1990403 embryonic brain development(GO:1990403)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0097224 sperm connecting piece(GO:0097224)
0.2 0.7 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.2 0.6 GO:0018444 translation release factor complex(GO:0018444)
0.2 0.5 GO:0016938 kinesin I complex(GO:0016938)
0.1 0.8 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.5 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.1 0.7 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.9 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 1.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 1.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.3 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
0.1 1.8 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.8 GO:0042611 MHC protein complex(GO:0042611) MHC class I protein complex(GO:0042612)
0.1 3.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.5 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.5 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.3 GO:0001652 granular component(GO:0001652)
0.0 1.0 GO:0000786 nucleosome(GO:0000786)
0.0 0.4 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.4 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 2.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 1.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 4.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.7 GO:0045495 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.3 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 1.0 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.7 GO:0000145 exocyst(GO:0000145)
0.0 0.7 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.4 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.2 GO:0044754 autolysosome(GO:0044754)
0.0 0.4 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 1.0 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.2 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 2.4 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.1 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 5.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.8 GO:0035580 specific granule lumen(GO:0035580)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.3 1.0 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.3 2.5 GO:0034056 estrogen response element binding(GO:0034056)
0.2 0.6 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.2 1.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 0.7 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.2 0.7 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.2 0.5 GO:0005174 CD40 receptor binding(GO:0005174)
0.2 0.7 GO:0004923 interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981)
0.2 1.0 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 1.5 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 1.9 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 1.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.5 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.6 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 1.2 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.4 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.3 GO:0090541 MIT domain binding(GO:0090541)
0.1 0.3 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.3 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.1 3.9 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.1 0.5 GO:0004803 transposase activity(GO:0004803)
0.1 0.3 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.1 1.5 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 1.2 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 0.8 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.7 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 0.8 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.3 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 0.2 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 0.6 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 6.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.7 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 1.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.7 GO:0031013 troponin I binding(GO:0031013)
0.1 0.4 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.6 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.4 GO:0019863 IgE binding(GO:0019863)
0.1 0.2 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.1 0.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 0.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 3.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.6 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.3 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.1 0.4 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.9 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 1.0 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.2 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.9 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.4 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.8 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.2 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.3 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.5 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 1.2 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.6 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0016855 L-serine ammonia-lyase activity(GO:0003941) racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.4 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0 0.3 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.2 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 0.4 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.3 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.4 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.4 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.4 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.6 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.4 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.2 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.6 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.1 GO:0022858 hydrogen:amino acid symporter activity(GO:0005280) L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.1 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.0 0.3 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.3 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0042282 hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.3 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 1.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 0.3 GO:0046965 retinoid X receptor binding(GO:0046965)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.7 PID IL27 PATHWAY IL27-mediated signaling events
0.0 4.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.9 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.4 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.1 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.1 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 1.0 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.7 PID BMP PATHWAY BMP receptor signaling
0.0 0.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.6 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.1 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 0.8 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.4 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 1.1 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.8 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.1 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.1 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus