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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for RBPJ

Z-value: 0.82

Motif logo

Transcription factors associated with RBPJ

Gene Symbol Gene ID Gene Info
ENSG00000168214.21 RBPJ

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RBPJhg38_v1_chr4_+_26320782_26320825,
hg38_v1_chr4_+_26321192_26321299
0.683.9e-05Click!

Activity profile of RBPJ motif

Sorted Z-values of RBPJ motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RBPJ

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_-_100993409 4.62 ENST00000471714.6
ABI family member 3 binding protein
chr3_-_100993507 4.56 ENST00000284322.10
ABI family member 3 binding protein
chr3_-_45915698 4.14 ENST00000539217.5
leucine zipper transcription factor like 1
chr3_-_19934189 3.66 ENST00000295824.14
EF-hand domain family member B
chr19_+_50203607 3.03 ENST00000642316.2
ENST00000425460.6
ENST00000440075.6
ENST00000376970.6
ENST00000599920.5
myosin heavy chain 14
chr1_-_223363337 2.40 ENST00000608996.5
sushi domain containing 4
chrX_+_38006551 2.33 ENST00000297875.7
synaptotagmin like 5
chr1_-_223364059 2.33 ENST00000343846.7
ENST00000484758.6
ENST00000344029.6
ENST00000366878.9
ENST00000494793.6
ENST00000681285.1
ENST00000680429.1
ENST00000681669.1
ENST00000681305.1
sushi domain containing 4
chr20_+_44582549 1.99 ENST00000372886.6
cAMP-dependent protein kinase inhibitor gamma
chr7_-_120858066 1.96 ENST00000222747.8
tetraspanin 12
chr5_+_42423433 1.86 ENST00000230882.9
growth hormone receptor
chr6_+_125749623 1.77 ENST00000368364.4
hes related family bHLH transcription factor with YRPW motif 2
chr1_+_61404076 1.60 ENST00000357977.5
nuclear factor I A
chr15_+_40405787 1.57 ENST00000610693.5
ENST00000479013.7
ENST00000487418.8
isovaleryl-CoA dehydrogenase
chr3_+_69763726 1.54 ENST00000448226.9
melanocyte inducing transcription factor
chr7_-_120857124 1.50 ENST00000441017.5
ENST00000424710.5
ENST00000433758.5
tetraspanin 12
chr11_+_111918900 1.38 ENST00000278601.6
chromosome 11 open reading frame 52
chr5_-_124744513 1.38 ENST00000504926.5
zinc finger protein 608
chr11_-_119340816 1.34 ENST00000528368.3
C1q and TNF related 5
chr16_-_53703883 1.29 ENST00000262135.9
ENST00000564374.5
ENST00000566096.5
RPGRIP1 like
chr16_-_53703810 1.28 ENST00000569716.1
ENST00000562588.5
ENST00000621565.5
ENST00000562230.5
ENST00000563746.5
ENST00000568653.7
ENST00000647211.2
RPGRIP1 like
chr6_-_75493629 1.20 ENST00000393004.6
filamin A interacting protein 1
chr6_-_75493773 1.15 ENST00000237172.12
filamin A interacting protein 1
chr8_-_79767843 1.07 ENST00000337919.9
hes related family bHLH transcription factor with YRPW motif 1
chr2_+_37950432 1.04 ENST00000407257.5
ENST00000417700.6
ENST00000234195.7
ENST00000442857.5
regulator of microtubule dynamics 2
chr7_-_120858303 1.04 ENST00000415871.5
ENST00000430985.1
tetraspanin 12
chr19_-_50025936 0.98 ENST00000596445.5
ENST00000599538.5
VRK serine/threonine kinase 3
chr10_+_116545907 0.96 ENST00000369221.2
pancreatic lipase
chr8_-_79767462 0.96 ENST00000674295.1
ENST00000518733.1
ENST00000674418.1
ENST00000674358.1
ENST00000354724.8
hes related family bHLH transcription factor with YRPW motif 1
chr8_+_122781621 0.95 ENST00000314393.6
zinc fingers and homeoboxes 2
chr5_-_140564245 0.94 ENST00000412920.7
ENST00000511201.2
ENST00000354402.9
ENST00000356738.6
amyloid beta precursor protein binding family B member 3
chr3_+_32685128 0.93 ENST00000331889.10
ENST00000328834.9
CCR4-NOT transcription complex subunit 10
chr11_+_7576975 0.91 ENST00000684215.1
ENST00000650027.1
PPFIA binding protein 2
chr3_+_171843337 0.87 ENST00000334567.9
ENST00000619900.4
ENST00000450693.1
transmembrane protein 212
chr9_-_137028878 0.85 ENST00000625103.1
ENST00000614293.4
ATP binding cassette subfamily A member 2
chr16_-_1611985 0.85 ENST00000426508.7
intraflagellar transport 140
chr17_-_58529277 0.84 ENST00000579371.5
septin 4
chr7_+_74209989 0.84 ENST00000361082.7
ENST00000275635.11
ENST00000460943.6
ENST00000470709.1
linker for activation of T cells family member 2
chr19_-_45584810 0.83 ENST00000323060.3
outer mitochondrial membrane lipid metabolism regulator OPA3
chr1_+_113390495 0.82 ENST00000307546.14
membrane associated guanylate kinase, WW and PDZ domain containing 3
chr4_+_155667654 0.81 ENST00000513574.1
guanylate cyclase 1 soluble subunit alpha 1
chr17_-_58529344 0.81 ENST00000317268.7
septin 4
chr9_-_127950716 0.80 ENST00000373084.8
family with sequence similarity 102 member A
chr11_-_119340544 0.80 ENST00000530681.2
C1q and TNF related 5
chr17_-_58529303 0.79 ENST00000580844.5
septin 4
chr7_+_90709530 0.78 ENST00000406263.5
cyclin dependent kinase 14
chr7_+_90709816 0.78 ENST00000436577.3
cyclin dependent kinase 14
chr7_-_16465728 0.78 ENST00000307068.5
sclerostin domain containing 1
chr13_-_19782970 0.77 ENST00000427943.1
ENST00000619300.4
paraspeckle component 1
chr11_-_2270584 0.77 ENST00000331289.5
achaete-scute family bHLH transcription factor 2
chr7_+_129144691 0.75 ENST00000486685.3
tetraspanin 33
chr10_-_43648845 0.75 ENST00000374433.7
zinc finger protein 32
chr12_-_89656051 0.75 ENST00000261173.6
ATPase plasma membrane Ca2+ transporting 1
chr16_+_58025745 0.73 ENST00000219271.4
matrix metallopeptidase 15
chr12_-_89656093 0.73 ENST00000359142.7
ATPase plasma membrane Ca2+ transporting 1
chr19_+_3094348 0.72 ENST00000078429.9
G protein subunit alpha 11
chr7_+_90709231 0.72 ENST00000446790.5
ENST00000265741.7
cyclin dependent kinase 14
chr10_-_43648704 0.72 ENST00000395797.1
zinc finger protein 32
chr1_+_14945775 0.69 ENST00000400797.3
kazrin, periplakin interacting protein
chr3_+_69763549 0.68 ENST00000472437.5
melanocyte inducing transcription factor
chr13_-_19782923 0.66 ENST00000338910.9
paraspeckle component 1
chr11_-_124935973 0.62 ENST00000298251.5
hepatic and glial cell adhesion molecule
chr16_-_70685975 0.61 ENST00000338779.11
MTSS I-BAR domain containing 2
chr2_+_218270392 0.60 ENST00000248451.7
ENST00000273077.9
PNKD metallo-beta-lactamase domain containing
chr1_-_91021996 0.59 ENST00000337393.10
zinc finger protein 644
chr6_-_116060859 0.55 ENST00000606080.2
fyn related Src family tyrosine kinase
chr19_-_39204254 0.52 ENST00000318438.7
syncollin
chr3_-_184017863 0.51 ENST00000427120.6
ENST00000334444.11
ENST00000392579.6
ENST00000382494.6
ENST00000265586.10
ENST00000446941.2
ATP binding cassette subfamily C member 5
chr10_+_122560639 0.49 ENST00000344338.7
ENST00000330163.8
ENST00000652446.2
ENST00000666315.1
ENST00000368955.7
ENST00000368909.7
ENST00000368956.6
ENST00000619379.1
deleted in malignant brain tumors 1
chr10_+_58385395 0.49 ENST00000487519.6
ENST00000373895.7
transcription factor A, mitochondrial
chr7_+_30771388 0.48 ENST00000265299.6
MINDY lysine 48 deubiquitinase 4
chr18_+_13218195 0.48 ENST00000679167.1
low density lipoprotein receptor class A domain containing 4
chr20_+_46008900 0.47 ENST00000372330.3
matrix metallopeptidase 9
chr19_+_19405655 0.46 ENST00000683918.1
GATA zinc finger domain containing 2A
chr11_+_64285219 0.46 ENST00000377702.8
G protein-coupled receptor 137
chr8_-_100336184 0.43 ENST00000519527.5
ENST00000522369.5
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr10_+_122560679 0.43 ENST00000657942.1
deleted in malignant brain tumors 1
chr16_+_1612337 0.43 ENST00000674071.1
ENST00000397412.8
cramped chromatin regulator homolog 1
chr3_-_132037800 0.42 ENST00000617767.4
copine 4
chr4_+_183905266 0.42 ENST00000308497.9
storkhead box 2
chr2_+_3595049 0.41 ENST00000236693.11
ENST00000349077.9
collectin subfamily member 11
chr6_-_134052594 0.41 ENST00000275230.6
solute carrier family 2 member 12
chr5_-_137735997 0.41 ENST00000505853.1
kelch like family member 3
chr4_+_155667198 0.40 ENST00000296518.11
guanylate cyclase 1 soluble subunit alpha 1
chr19_-_55597753 0.40 ENST00000587678.1
FLT3 interacting zinc finger 1
chr1_-_2530256 0.40 ENST00000378453.4
hes family bHLH transcription factor 5
chr3_+_142723999 0.39 ENST00000476941.6
ENST00000273482.10
transient receptor potential cation channel subfamily C member 1
chr10_-_48251757 0.37 ENST00000305531.3
FERM and PDZ domain containing 2
chr11_+_64285472 0.37 ENST00000535675.5
ENST00000543383.5
G protein-coupled receptor 137
chr11_+_64285839 0.37 ENST00000438980.7
ENST00000540370.1
G protein-coupled receptor 137
chr16_+_23302292 0.37 ENST00000343070.7
sodium channel epithelial 1 subunit beta
chr1_-_92486049 0.35 ENST00000427103.5
growth factor independent 1 transcriptional repressor
chr7_+_74209947 0.35 ENST00000475494.5
ENST00000398475.5
linker for activation of T cells family member 2
chr1_-_39639626 0.34 ENST00000372852.4
hes related family bHLH transcription factor with YRPW motif like
chr10_+_113679839 0.34 ENST00000369318.8
ENST00000369315.5
caspase 7
chr9_+_99821876 0.33 ENST00000395097.7
nuclear receptor subfamily 4 group A member 3
chr10_-_27242068 0.33 ENST00000375901.5
ENST00000412279.1
ENST00000676731.1
ENST00000679220.1
ENST00000678392.1
ENST00000678446.1
ENST00000677441.1
ENST00000375905.8
acyl-CoA binding domain containing 5
chr6_-_32224060 0.32 ENST00000375023.3
notch receptor 4
chrX_+_19343893 0.30 ENST00000540249.5
ENST00000545074.5
ENST00000379806.9
ENST00000423505.5
ENST00000422285.7
ENST00000417819.5
ENST00000355808.9
ENST00000379805.3
pyruvate dehydrogenase E1 subunit alpha 1
chr2_+_105744876 0.30 ENST00000233154.9
ENST00000451463.6
NCK adaptor protein 2
chr10_+_122560751 0.30 ENST00000338354.10
ENST00000664692.1
ENST00000653442.1
ENST00000664974.1
deleted in malignant brain tumors 1
chrX_-_70260199 0.29 ENST00000374519.4
pyrimidinergic receptor P2Y4
chr1_-_85404494 0.29 ENST00000633113.1
dimethylarginine dimethylaminohydrolase 1
chr17_-_16215520 0.29 ENST00000582357.5
ENST00000436828.5
ENST00000268712.8
ENST00000411510.5
ENST00000395857.7
nuclear receptor corepressor 1
chr2_-_218270099 0.29 ENST00000248450.9
ENST00000444053.5
angio associated migratory cell protein
chr2_-_40430257 0.29 ENST00000408028.6
ENST00000332839.8
ENST00000406391.2
ENST00000405901.7
solute carrier family 8 member A1
chr9_-_101594918 0.28 ENST00000374806.2
protein phosphatase 3 regulatory subunit B, beta
chr2_+_169733811 0.28 ENST00000392647.7
kelch like family member 23
chr1_+_156767526 0.28 ENST00000271526.9
proline rich mitotic checkpoint control factor
chr1_+_43389889 0.28 ENST00000562955.2
ENST00000634258.3
SZT2 subunit of KICSTOR complex
chr20_+_2652622 0.27 ENST00000329276.10
ENST00000445139.1
NOP56 ribonucleoprotein
chr9_-_101594995 0.26 ENST00000636434.1
protein phosphatase 3 regulatory subunit B, beta
chr10_+_113679523 0.26 ENST00000345633.8
ENST00000614447.4
ENST00000369321.6
caspase 7
chr1_+_174799895 0.25 ENST00000489615.5
RAB GTPase activating protein 1 like
chr19_+_50025714 0.25 ENST00000598809.5
ENST00000595661.5
ENST00000391821.6
zinc finger protein 473
chr21_+_6499203 0.25 ENST00000619537.5
crystallin alpha A2
chr5_+_38445539 0.25 ENST00000397210.7
ENST00000506135.5
ENST00000508131.5
EGF like, fibronectin type III and laminin G domains
chr2_+_109898685 0.24 ENST00000480744.2
LIM zinc finger domain containing 3
chr8_+_66432475 0.23 ENST00000415254.5
ENST00000396623.8
alcohol dehydrogenase iron containing 1
chr17_+_58169401 0.23 ENST00000641866.1
olfactory receptor family 4 subfamily D member 2
chr19_+_43596480 0.23 ENST00000533118.5
zinc finger protein 576
chr11_+_64285533 0.23 ENST00000538032.5
G protein-coupled receptor 137
chr6_+_30884063 0.23 ENST00000511510.5
ENST00000376569.7
ENST00000376570.8
ENST00000504927.5
discoidin domain receptor tyrosine kinase 1
chr11_+_66616606 0.22 ENST00000393979.3
ENST00000409372.1
ENST00000310137.5
ENST00000443702.1
ENST00000409738.4
ENST00000412278.2
ENST00000500635.2
RNA binding motif protein 14
RBM14-RBM4 readthrough
chr4_+_26319636 0.22 ENST00000342295.6
ENST00000506956.5
ENST00000512671.6
ENST00000345843.8
recombination signal binding protein for immunoglobulin kappa J region
chr7_-_27130182 0.22 ENST00000511914.1
homeobox A4
chr15_+_59438149 0.22 ENST00000288228.10
ENST00000559628.5
ENST00000557914.5
ENST00000560474.5
family with sequence similarity 81 member A
chr10_-_95441015 0.21 ENST00000371241.5
ENST00000354106.7
ENST00000371239.5
ENST00000361941.7
ENST00000277982.9
ENST00000371245.7
sorbin and SH3 domain containing 1
chr8_+_106726012 0.20 ENST00000449762.6
ENST00000297447.10
oxidation resistance 1
chr4_+_155667096 0.20 ENST00000393832.7
guanylate cyclase 1 soluble subunit alpha 1
chr9_+_99821846 0.20 ENST00000338488.8
ENST00000618101.4
nuclear receptor subfamily 4 group A member 3
chr9_-_133609325 0.20 ENST00000673969.1
family with sequence similarity 163 member B
chr19_-_55179390 0.20 ENST00000590851.5
synaptotagmin 5
chr3_+_169773384 0.20 ENST00000349841.10
ENST00000356716.8
myoneurin
chr14_+_73136418 0.20 ENST00000557356.5
ENST00000556864.5
ENST00000556533.5
ENST00000556951.5
ENST00000557293.5
ENST00000553719.5
ENST00000553599.5
ENST00000556011.5
ENST00000394157.7
ENST00000357710.8
ENST00000560005.6
ENST00000555254.5
ENST00000554131.5
ENST00000324501.10
ENST00000557037.5
presenilin 1
chr4_+_26320563 0.19 ENST00000361572.10
recombination signal binding protein for immunoglobulin kappa J region
chr19_-_40218339 0.19 ENST00000311308.6
tetratricopeptide repeat domain 9B
chr4_+_26320975 0.19 ENST00000509158.6
ENST00000681856.1
ENST00000680140.1
ENST00000355476.8
ENST00000680511.1
recombination signal binding protein for immunoglobulin kappa J region
chrX_+_123859807 0.19 ENST00000434753.7
ENST00000430625.1
X-linked inhibitor of apoptosis
chr5_-_39074377 0.19 ENST00000514735.1
ENST00000357387.8
ENST00000296782.9
RPTOR independent companion of MTOR complex 2
chr14_-_21526391 0.18 ENST00000611430.4
spalt like transcription factor 2
chr3_+_156142962 0.18 ENST00000471742.5
potassium voltage-gated channel subfamily A member regulatory beta subunit 1
chr3_-_49929800 0.17 ENST00000455683.6
MON1 homolog A, secretory trafficking associated
chr5_-_138178599 0.17 ENST00000454473.5
ENST00000418329.5
ENST00000254900.10
ENST00000230901.9
ENST00000402931.5
ENST00000411594.6
ENST00000430331.1
bromodomain containing 8
chr19_+_36687579 0.17 ENST00000682579.1
ENST00000536254.6
zinc finger protein 567
chr19_+_43596388 0.16 ENST00000391965.6
ENST00000525771.1
zinc finger protein 576
chrX_-_153971169 0.16 ENST00000369984.4
host cell factor C1
chr10_-_73167961 0.15 ENST00000372979.9
ecdysoneless cell cycle regulator
chr11_-_8268716 0.15 ENST00000428101.6
LIM domain only 1
chr14_-_52791462 0.15 ENST00000650397.1
ENST00000554230.5
glucosamine-phosphate N-acetyltransferase 1
chr4_+_26320782 0.15 ENST00000514807.5
ENST00000348160.9
recombination signal binding protein for immunoglobulin kappa J region
chr17_-_8087709 0.14 ENST00000647874.1
arachidonate 12-lipoxygenase, 12R type
chr1_+_43389874 0.14 ENST00000372450.8
SZT2 subunit of KICSTOR complex
chrX_+_123859976 0.14 ENST00000371199.8
X-linked inhibitor of apoptosis
chr21_-_6499202 0.13 ENST00000619610.2
ENST00000610664.5
ENST00000639996.1
U2 small nuclear RNA auxiliary factor 1 like 5
chr12_-_31792290 0.13 ENST00000340398.5
H3.5 histone
chr10_-_73168052 0.13 ENST00000430082.6
ENST00000454759.6
ENST00000413026.1
ENST00000453402.5
ecdysoneless cell cycle regulator
chr5_+_141412979 0.13 ENST00000612503.1
ENST00000398610.3
protocadherin gamma subfamily A, 10
chr6_-_31542339 0.12 ENST00000458640.5
DExD-box helicase 39B
chr9_-_95507416 0.12 ENST00000429896.6
patched 1
chr4_+_70195719 0.12 ENST00000683306.1
odontogenic, ameloblast associated
chr16_-_70685791 0.11 ENST00000616026.4
MTSS I-BAR domain containing 2
chr2_-_79087986 0.11 ENST00000305089.8
regenerating family member 1 beta
chr1_+_6451578 0.11 ENST00000434576.2
ENST00000477679.2
espin
chr15_-_77696142 0.10 ENST00000561030.5
leucine rich repeat and Ig domain containing 1
chr10_-_37857582 0.10 ENST00000395867.8
ENST00000611278.4
zinc finger protein 248
chr8_+_106726115 0.10 ENST00000521592.5
oxidation resistance 1
chr2_+_43774033 0.09 ENST00000260605.12
ENST00000406852.7
ENST00000398823.6
ENST00000605786.5
dynein cytoplasmic 2 light intermediate chain 1
chr19_+_34926892 0.09 ENST00000303586.11
ENST00000601142.2
ENST00000439785.5
ENST00000601540.5
ENST00000601957.5
zinc finger protein 30
chr6_-_26056460 0.09 ENST00000343677.4
H1.2 linker histone, cluster member
chr6_+_30884353 0.09 ENST00000428153.6
ENST00000376568.8
ENST00000452441.5
ENST00000515219.5
discoidin domain receptor tyrosine kinase 1
chr12_+_6200759 0.09 ENST00000645565.1
ENST00000382515.7
CD9 molecule
chr1_-_7940825 0.09 ENST00000377507.8
TNF receptor superfamily member 9
chr1_-_197775298 0.08 ENST00000367396.7
DENN domain containing 1B
chrX_-_74614612 0.08 ENST00000349225.2
ENST00000332687.11
ring finger protein, LIM domain interacting
chr5_+_178895892 0.08 ENST00000520660.5
ENST00000361362.7
ENST00000520805.5
ZFP2 zinc finger protein
chr1_-_43389768 0.08 ENST00000372455.4
ENST00000372457.9
ENST00000290663.10
mediator complex subunit 8
chr11_+_112961480 0.08 ENST00000621850.4
neural cell adhesion molecule 1
chr12_+_4649097 0.07 ENST00000648836.1
ENST00000266544.10
novel protein
NADH:ubiquinone oxidoreductase subunit A9
chr12_-_7695752 0.07 ENST00000329913.4
growth differentiation factor 3
chrX_-_119791620 0.07 ENST00000361575.4
ribosomal protein L39
chr12_-_16606795 0.07 ENST00000447609.5
LIM domain only 3
chr7_+_102912983 0.07 ENST00000339431.9
ENST00000249377.4
leucine rich repeat containing 17
chr16_+_21953341 0.07 ENST00000268379.9
ENST00000561553.5
ENST00000565331.5
ubiquinol-cytochrome c reductase core protein 2
chr14_-_21526312 0.07 ENST00000537235.2
spalt like transcription factor 2
chr7_-_151227035 0.07 ENST00000441774.1
ENST00000287844.7
ENST00000222388.6
ATP binding cassette subfamily F member 2
ABCF2-H2BE1 readthrough
chr10_-_37858037 0.06 ENST00000395873.7
ENST00000357328.8
ENST00000395874.2
zinc finger protein 248
chr4_-_175812746 0.05 ENST00000393658.6
glycoprotein M6A
chr16_+_85611401 0.05 ENST00000405402.6
Gse1 coiled-coil protein
chr19_-_45584769 0.05 ENST00000263275.5
outer mitochondrial membrane lipid metabolism regulator OPA3
chrX_-_53686710 0.05 ENST00000262854.11
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
chr8_+_67952028 0.05 ENST00000288368.5
phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2
chr22_-_31489761 0.05 ENST00000344710.9
ENST00000330125.10
ENST00000397518.5
eukaryotic translation initiation factor 4E nuclear import factor 1
chr5_-_116536458 0.05 ENST00000510263.5
semaphorin 6A
chr2_+_170715317 0.04 ENST00000375281.4
Sp5 transcription factor
chr11_-_67523396 0.03 ENST00000353903.9
ENST00000294288.5
calcium binding protein 2
chr12_-_4649043 0.03 ENST00000545990.6
ENST00000228850.6
A-kinase anchoring protein 3
chrX_+_106802660 0.03 ENST00000357242.10
ENST00000310452.6
ENST00000481617.6
ENST00000276175.7
TBC1 domain family member 8B
chr1_+_7961894 0.03 ENST00000377491.5
ENST00000377488.5
Parkinsonism associated deglycase
chr2_+_186486246 0.03 ENST00000337859.11
zinc finger CCCH-type containing 15

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:1903565 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
1.3 3.8 GO:0036304 umbilical cord morphogenesis(GO:0036304) umbilical cord development(GO:0061027)
0.3 1.9 GO:0000255 allantoin metabolic process(GO:0000255)
0.2 0.6 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.2 0.8 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 1.5 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.2 0.5 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 1.6 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.5 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.1 2.6 GO:0021670 lateral ventricle development(GO:0021670)
0.1 0.8 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.4 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 1.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.8 GO:1905068 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 4.5 GO:0010842 retina layer formation(GO:0010842)
0.1 0.8 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 2.0 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.4 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.1 3.9 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.8 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 0.3 GO:1902530 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.1 0.4 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.1 0.2 GO:0015993 molecular hydrogen transport(GO:0015993)
0.1 0.6 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 0.3 GO:0072014 proximal tubule development(GO:0072014)
0.1 0.7 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.5 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.1 0.4 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.2 GO:0019046 release from viral latency(GO:0019046)
0.1 1.6 GO:0072189 ureter development(GO:0072189)
0.0 0.3 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0 0.3 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 1.0 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.0 2.2 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 8.1 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 2.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.0 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 4.7 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.5 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.3 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.2 GO:0001777 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.5 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.3 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.3 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 2.0 GO:0070206 protein trimerization(GO:0070206)
0.0 0.1 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.3 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.3 GO:0006527 arginine catabolic process(GO:0006527)
0.0 1.2 GO:0002279 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.0 0.1 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.8 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.9 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.7 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.1 GO:0007549 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.0 0.4 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0070195 growth hormone receptor complex(GO:0070195)
0.6 3.0 GO:0097513 myosin II filament(GO:0097513)
0.3 9.2 GO:0005614 interstitial matrix(GO:0005614)
0.3 2.3 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 2.6 GO:0005879 axonemal microtubule(GO:0005879)
0.1 1.4 GO:0042382 paraspeckles(GO:0042382)
0.1 0.9 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 2.1 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.8 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.8 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.8 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 1.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 1.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.4 GO:1990130 Iml1 complex(GO:1990130)
0.0 1.7 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.3 GO:0097255 R2TP complex(GO:0097255)
0.0 0.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.3 GO:0070761 box C/D snoRNP complex(GO:0031428) pre-snoRNP complex(GO:0070761)
0.0 0.7 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.7 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 2.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.4 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:0035939 microsatellite binding(GO:0035939)
0.9 2.6 GO:0031862 prostanoid receptor binding(GO:0031862)
0.4 1.2 GO:0035375 zymogen binding(GO:0035375)
0.2 0.6 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.2 0.7 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.2 4.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.5 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.1 3.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.8 GO:0098821 BMP receptor activity(GO:0098821)
0.1 0.3 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 1.6 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 1.9 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 8.7 GO:0005518 collagen binding(GO:0005518)
0.1 1.9 GO:0070064 proline-rich region binding(GO:0070064)
0.0 2.4 GO:0030332 cyclin binding(GO:0030332)
0.0 1.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.8 GO:0000150 recombinase activity(GO:0000150)
0.0 0.3 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 3.0 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 1.0 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.5 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 2.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.6 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 1.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.0 GO:1903135 cupric ion binding(GO:1903135)
0.0 0.8 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.9 GO:0001540 beta-amyloid binding(GO:0001540)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 10.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.2 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.9 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 1.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.5 ST GA12 PATHWAY G alpha 12 Pathway
0.0 2.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID INSULIN PATHWAY Insulin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 2.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.8 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.0 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport