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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for RFX3_RFX2

Z-value: 14.13

Motif logo

Transcription factors associated with RFX3_RFX2

Gene Symbol Gene ID Gene Info
ENSG00000080298.16 RFX3
ENSG00000087903.13 RFX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RFX2hg38_v1_chr19_-_6110463_61105410.991.0e-23Click!
RFX3hg38_v1_chr9_-_3525968_35260170.972.5e-19Click!

Activity profile of RFX3_RFX2 motif

Sorted Z-values of RFX3_RFX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RFX3_RFX2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr21_-_42496186 225.94 ENST00000398352.3
ENST00000291536.8
radial spoke head component 1
chr1_-_109113818 181.42 ENST00000369949.8
chromosome 1 open reading frame 194
chr1_-_159900112 146.32 ENST00000479940.2
ENST00000368099.9
cilia and flagella associated protein 45
chr16_-_67393486 129.15 ENST00000562206.1
ENST00000393957.7
ENST00000290942.9
tubulin polymerization promoting protein family member 3
chr22_+_23145366 122.33 ENST00000341989.9
ENST00000263116.8
RAB36, member RAS oncogene family
chr15_+_70892443 118.56 ENST00000443425.6
ENST00000560369.5
leucine rich repeat containing 49
chr15_+_70892809 114.12 ENST00000260382.10
ENST00000560755.5
leucine rich repeat containing 49
chr17_-_6831716 113.98 ENST00000338694.7
tektin 1
chr17_-_76141240 112.33 ENST00000322957.7
forkhead box J1
chr2_+_227871618 106.18 ENST00000309931.3
ENST00000440997.1
dynein assembly factor with WD repeats 1
chrX_-_48835553 103.65 ENST00000218230.6
proprotein convertase subtilisin/kexin type 1 inhibitor
chr11_+_111514772 100.12 ENST00000375618.9
ENST00000529167.5
ENST00000332814.6
HOATZ cilia and flagella associated protein
chr1_-_169427408 99.13 ENST00000367806.7
coiled-coil domain containing 181
chr3_-_50345665 99.03 ENST00000442887.1
ENST00000231749.8
ENST00000360165.7
zinc finger MYND-type containing 10
chr3_-_197949869 99.00 ENST00000452735.1
ENST00000453254.5
ENST00000455191.5
IQ motif containing G
chr1_+_37556913 96.81 ENST00000296218.8
ENST00000652629.1
dynein axonemal light intermediate chain 1
chr9_+_122159886 94.64 ENST00000373764.8
ENST00000536616.5
MORN repeat containing 5
chr2_-_130144994 91.82 ENST00000457413.1
ENST00000409128.5
ENST00000441670.1
ENST00000409234.3
ENST00000409943.8
ENST00000392984.7
ENST00000310463.10
coiled-coil domain containing 74B
chr11_-_75668566 90.48 ENST00000526740.3
microtubule associated protein 6
chr11_+_102047422 89.71 ENST00000434758.7
ENST00000526781.5
ENST00000534360.1
cilia and flagella associated protein 300
chr7_+_48035511 89.63 ENST00000420324.5
ENST00000539619.5
ENST00000435376.5
ENST00000430738.5
ENST00000348904.4
chromosome 7 open reading frame 57
chr3_-_167380270 88.06 ENST00000392764.5
ENST00000675490.1
ENST00000474464.5
ENST00000392766.6
ENST00000485651.5
zinc finger B-box domain containing
chr2_+_131527833 87.28 ENST00000295171.10
ENST00000467992.6
ENST00000409856.8
coiled-coil domain containing 74A
chr3_-_169812866 84.99 ENST00000446859.7
ENST00000522830.5
ENST00000522526.6
leucine rich repeat containing 34
chr1_+_217631337 84.95 ENST00000366933.5
spermatogenesis associated 17
chr17_+_9576627 82.82 ENST00000396219.7
ENST00000352665.10
cilia and flagella associated protein 52
chr6_+_52420107 79.63 ENST00000636489.1
ENST00000637089.1
ENST00000637353.1
ENST00000637263.1
EF-hand domain containing 1
chr8_-_48735248 79.19 ENST00000262103.8
ENST00000523092.5
ENST00000433756.1
EF-hand calcium binding domain 1
chrX_+_107206605 79.14 ENST00000372453.8
dynein axonemal assembly factor 6
chrX_+_107206632 79.07 ENST00000535523.5
ENST00000673764.1
dynein axonemal assembly factor 6
chr12_+_6904733 78.64 ENST00000007969.12
ENST00000622489.4
ENST00000443597.7
ENST00000323702.9
leucine rich repeat containing 23
chr6_+_43645011 78.62 ENST00000372163.5
ENST00000372165.8
radial spoke head component 9
chr1_+_151721508 78.23 ENST00000479191.2
regulatory subunit of type II PKA R-subunit domain containing 1
chr16_-_75556214 76.66 ENST00000568377.5
ENST00000565067.5
ENST00000258173.11
transmembrane protein 231
chr6_-_109440504 76.66 ENST00000520723.5
ENST00000518648.1
ENST00000417394.6
ENST00000521072.7
peptidylprolyl isomerase like 6
chr11_+_94512452 76.57 ENST00000542198.3
chromosome 11 open reading frame 97
chr12_+_6904962 73.98 ENST00000415834.5
ENST00000436789.5
leucine rich repeat containing 23
chr11_-_112073980 72.60 ENST00000532211.5
ENST00000528775.6
ENST00000280350.10
ENST00000431456.6
PIH1 domain containing 2
chr11_-_112074239 72.05 ENST00000530641.5
PIH1 domain containing 2
chr15_+_43510945 71.90 ENST00000382031.5
microtubule associated protein 1A
chr1_-_66924791 70.60 ENST00000371023.7
ENST00000371022.3
ENST00000371026.8
dynein axonemal intermediate chain 4
chr6_+_116616467 70.25 ENST00000229554.10
ENST00000368581.8
ENST00000368580.4
radial spoke head component 4A
chr6_+_112087576 68.66 ENST00000368656.7
ENST00000604268.1
family with sequence similarity 229 member B
chr2_-_74421560 68.46 ENST00000612891.4
ENST00000640331.1
ENST00000684111.1
chromosome 2 open reading frame 81
chr15_+_82262781 68.06 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000682753.1
ENST00000566861.5
ENST00000565432.1
stabilizer of axonemal microtubules 2
chr16_+_84145256 67.93 ENST00000378553.10
dynein axonemal assembly factor 1
chr19_-_7926106 65.70 ENST00000318978.6
cortexin 1
chr15_+_81134257 64.99 ENST00000286732.5
cilia and flagella associated protein 161
chr2_+_74421721 64.27 ENST00000409791.5
ENST00000348227.4
WD repeat domain 54
chr9_+_124853417 64.20 ENST00000613760.4
ENST00000618744.4
ENST00000373574.2
WD repeat domain 38
chr4_-_176195563 61.68 ENST00000280191.7
spermatogenesis associated 4
chr16_+_58249910 60.34 ENST00000219299.8
ENST00000443128.6
ENST00000616795.1
coiled-coil domain containing 113
chr1_-_183653307 60.29 ENST00000308641.6
apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4
chr20_-_3781440 59.38 ENST00000379756.3
sperm flagellar 1
chr16_+_67807082 59.10 ENST00000567852.5
ENST00000565148.5
ENST00000388833.7
ENST00000561654.5
ENST00000431934.2
translin associated factor X interacting protein 1
chr1_+_161098320 58.48 ENST00000368011.9
ENST00000392192.6
kelch domain containing 9
chr16_+_57694788 58.46 ENST00000569375.5
ENST00000569167.1
ENST00000394337.8
ENST00000360716.8
ENST00000563126.5
ENST00000336825.12
dynein regulatory complex subunit 7
chr1_+_111346590 58.04 ENST00000369737.4
ENST00000369738.9
primary cilia formation
chr1_-_36450279 57.62 ENST00000445843.7
organic solute carrier partner 1
chr16_+_67806765 56.98 ENST00000415766.7
ENST00000561639.6
translin associated factor X interacting protein 1
chr6_+_52420332 56.49 ENST00000636107.1
ENST00000371068.11
ENST00000636702.1
ENST00000635996.1
ENST00000636379.1
EF-hand domain containing 1
chr6_-_165309598 56.42 ENST00000230301.9
chromosome 6 open reading frame 118
chr17_+_63998344 55.87 ENST00000577953.5
ENST00000582540.5
ENST00000579184.5
ENST00000425164.7
ENST00000412177.6
ENST00000583891.5
ENST00000580752.1
proline rich 29
chr10_-_25016105 55.59 ENST00000376363.5
ENST00000331161.9
enkurin, TRPC channel interacting protein
chr1_-_113759099 54.58 ENST00000393357.6
ENST00000446739.1
putative homeodomain transcription factor 1
chr3_-_129428590 54.55 ENST00000503957.1
ENST00000505956.6
ENST00000326085.7
EF-hand calcium binding domain 12
chr3_-_108222362 54.26 ENST00000492106.1
intraflagellar transport 57
chr10_+_61662921 54.23 ENST00000648843.3
ENST00000330194.2
ENST00000389639.3
ciliary associated calcium binding coiled-coil 1
chr13_+_30932638 54.14 ENST00000380473.8
testis expressed 26
chr7_+_77122609 54.00 ENST00000285871.5
coiled-coil domain containing 146
chr6_-_43510686 53.64 ENST00000372441.1
leucine rich repeat containing 73
chr1_-_169427428 53.41 ENST00000456107.1
ENST00000367805.7
ENST00000491570.2
coiled-coil domain containing 181
chr1_-_36450410 52.00 ENST00000356637.9
ENST00000354267.3
ENST00000235532.9
organic solute carrier partner 1
chr3_+_158571171 51.75 ENST00000484955.5
ENST00000359117.9
ENST00000619577.5
ENST00000471745.5
ENST00000477042.6
ENST00000650753.1
ENST00000651984.1
ENST00000355893.11
ENST00000466246.7
ENST00000469452.5
ENST00000482628.5
myeloid leukemia factor 1
chr16_-_30762052 51.53 ENST00000543610.6
ENST00000545825.1
ENST00000541260.5
coiled-coil domain containing 189
chr3_+_158571153 51.40 ENST00000491767.6
ENST00000618075.4
myeloid leukemia factor 1
chr1_+_20186076 50.42 ENST00000375099.4
UBX domain protein 10
chr17_+_7857987 50.04 ENST00000332439.5
cytochrome b5 domain containing 1
chr9_+_132878873 49.91 ENST00000356311.10
ENST00000350499.6
sperm acrosome associated 9
chr12_-_25195074 48.99 ENST00000354189.9
ENST00000676236.1
ENST00000545133.5
ENST00000554347.1
ENST00000674567.1
ENST00000395987.8
ENST00000320267.13
ENST00000395990.6
cilia and flagella associated protein 94
chr11_-_8593940 48.90 ENST00000315204.5
ENST00000396672.5
ENST00000431279.6
ENST00000418597.5
serine/threonine kinase 33
chr2_+_38875962 48.29 ENST00000340556.11
ENST00000410014.5
ENST00000644631.3
ENST00000409665.5
ENST00000409077.2
ENST00000409131.2
MORN repeat containing 2
chr11_+_61508742 48.23 ENST00000378075.4
leucine rich repeat containing 10B
chr6_+_108848387 47.93 ENST00000368972.7
ENST00000392644.9
armadillo repeat containing 2
chr7_+_139133744 47.57 ENST00000430935.5
ENST00000495038.5
ENST00000474035.6
ENST00000478836.6
ENST00000464848.5
ENST00000343187.8
tetratricopeptide repeat domain 26
chr15_-_68205319 47.47 ENST00000467889.3
ENST00000448060.7
calmodulin like 4
chr10_+_22345445 47.42 ENST00000376603.6
ENST00000456231.6
ENST00000376624.8
ENST00000313311.10
ENST00000435326.5
sperm associated antigen 6
chr11_-_8594181 47.37 ENST00000358872.7
ENST00000454443.2
serine/threonine kinase 33
chr14_+_99793329 47.26 ENST00000334192.8
EMAP like 1
chr8_-_132675533 47.18 ENST00000620350.5
ENST00000518642.5
ENST00000250173.5
leucine rich repeat containing 6
chr3_+_97764521 46.96 ENST00000335979.6
ENST00000394206.5
ENST00000462412.2
ADP ribosylation factor like GTPase 6
chr3_+_158571215 46.53 ENST00000498592.6
ENST00000478894.7
myeloid leukemia factor 1
chr17_+_410306 46.47 ENST00000360127.7
ENST00000571106.1
ENST00000491373.1
chromosome 17 open reading frame 97
chr1_-_118185157 46.33 ENST00000336338.10
sperm associated antigen 17
chr1_+_109114097 46.00 ENST00000457623.6
ENST00000369939.8
ENST00000529753.5
endosome-lysosome associated apoptosis and autophagy regulator 1
chr19_-_55166632 43.95 ENST00000532817.5
ENST00000527223.6
ENST00000391720.8
dynein axonemal assembly factor 3
chr19_-_55166671 43.57 ENST00000455045.5
dynein axonemal assembly factor 3
chr19_-_55166565 43.33 ENST00000526003.5
ENST00000534170.5
ENST00000524407.7
dynein axonemal assembly factor 3
chr2_+_169479445 43.33 ENST00000513963.1
ENST00000392663.6
ENST00000295240.8
novel protein
Bardet-Biedl syndrome 5
chr15_-_68205274 42.82 ENST00000540479.6
calmodulin like 4
chr11_-_62706234 42.67 ENST00000403550.5
BSCL2 lipid droplet biogenesis associated, seipin
chrX_+_119896157 42.63 ENST00000371422.5
ENST00000334356.2
A-kinase anchoring protein 14
chr22_-_37953541 42.43 ENST00000422191.1
ENST00000249079.6
ENST00000403305.6
ENST00000418863.5
ENST00000619227.4
ENST00000403026.5
chromosome 22 open reading frame 23
chr8_-_132675567 42.09 ENST00000519595.5
leucine rich repeat containing 6
chr1_-_113759464 42.06 ENST00000357783.6
ENST00000369604.6
putative homeodomain transcription factor 1
chr3_-_27369355 42.02 ENST00000429845.6
ENST00000341435.9
ENST00000435750.1
NIMA related kinase 10
chr11_-_62706304 41.52 ENST00000278893.11
ENST00000407022.7
ENST00000421906.5
BSCL2 lipid droplet biogenesis associated, seipin
chr16_+_89658025 41.15 ENST00000611218.1
ENST00000568929.1
spermatogenesis associated 33
chr1_-_48472166 41.11 ENST00000371847.8
ENST00000396199.7
spermatogenesis associated 6
chr1_-_113759338 41.02 ENST00000369598.5
ENST00000369600.5
putative homeodomain transcription factor 1
chr3_-_47282752 40.92 ENST00000456548.5
ENST00000432493.5
ENST00000684063.1
ENST00000444589.6
kinesin family member 9
chrX_+_119895837 40.46 ENST00000371425.8
ENST00000371431.8
A-kinase anchoring protein 14
chr1_+_244969976 40.19 ENST00000366522.6
EF-hand calcium binding domain 2
chr2_+_119544420 38.99 ENST00000413369.8
cilia and flagella associated protein 221
chr3_-_57544324 38.98 ENST00000495027.5
ENST00000351747.6
ENST00000389536.8
ENST00000311202.7
dynein axonemal heavy chain 12
chr12_+_121918581 38.91 ENST00000397454.2
ENST00000288912.9
cilia and flagella associated protein 251
chr3_-_108222383 38.80 ENST00000264538.4
intraflagellar transport 57
chr15_-_55498317 38.72 ENST00000568310.1
ENST00000565113.5
ENST00000448430.6
ENST00000457155.6
DNAAF4-CCPG1 readthrough (NMD candidate)
dynein axonemal assembly factor 4
chr3_+_97764728 38.28 ENST00000463745.6
ADP ribosylation factor like GTPase 6
chr20_+_2207217 37.43 ENST00000447956.5
ENST00000411839.1
ENST00000651531.1
novel transcript
novel protein
chr18_+_46946821 37.35 ENST00000245121.9
ENST00000356157.12
katanin catalytic subunit A1 like 2
chr17_-_5500997 37.11 ENST00000568641.2
novel protein
chr17_+_11598456 37.04 ENST00000579828.5
ENST00000262442.9
ENST00000454412.6
dynein axonemal heavy chain 9
chr7_-_103074816 36.95 ENST00000379305.7
ENST00000379308.7
F-box and leucine rich repeat protein 13
chr1_-_173669835 36.74 ENST00000333279.3
ankyrin repeat domain 45
chr16_+_57372481 36.46 ENST00000006053.7
C-X3-C motif chemokine ligand 1
chr3_-_19934189 35.86 ENST00000295824.14
EF-hand domain family member B
chr3_-_47282518 35.84 ENST00000425853.5
ENST00000452770.6
kinesin family member 9
chr17_-_58328756 35.77 ENST00000268893.10
ENST00000343736.9
TSPO associated protein 1
chr16_+_4734519 35.10 ENST00000299320.10
chromosome 16 open reading frame 71
chr14_-_50396872 34.98 ENST00000395834.6
cyclin dependent kinase like 1
chr9_-_114348966 34.66 ENST00000374079.8
AT-hook transcription factor
chr3_-_196712194 34.63 ENST00000399942.4
ENST00000409690.5
centrosomal protein 19
chr16_+_4734457 34.22 ENST00000590191.1
chromosome 16 open reading frame 71
chr18_-_74147816 34.18 ENST00000419743.7
ENST00000582526.1
F-box protein 15
chr2_-_177618705 33.80 ENST00000355689.6
tetratricopeptide repeat domain 30A
chr10_+_133160194 33.60 ENST00000478074.6
ENST00000684248.1
ENST00000304613.8
kinase non-catalytic C-lobe domain containing 1
chr1_+_66752441 33.59 ENST00000282670.7
dynein light chain Tctex-type family member 5
chr1_+_183636065 33.57 ENST00000304685.8
ral guanine nucleotide dissociation stimulator like 1
chr1_+_244969869 33.23 ENST00000366523.5
EF-hand calcium binding domain 2
chr18_-_50266481 33.12 ENST00000398545.5
cilia and flagella associated protein 53
chr22_-_37844308 32.91 ENST00000411961.6
ENST00000434930.1
ENST00000215941.9
ankyrin repeat domain 54
chr20_+_44531817 32.84 ENST00000372889.5
ENST00000372887.5
cAMP-dependent protein kinase inhibitor gamma
chr19_-_55179390 31.91 ENST00000590851.5
synaptotagmin 5
chr20_+_44531758 31.77 ENST00000372891.7
ENST00000372892.7
ENST00000372894.7
cAMP-dependent protein kinase inhibitor gamma
chr3_-_113441487 31.72 ENST00000393845.9
ENST00000295868.6
cilia and flagella associated protein 44
chr10_-_27983103 31.46 ENST00000672841.1
outer dynein arm docking complex subunit 2
chr22_+_38656627 31.24 ENST00000411557.5
ENST00000396811.6
ENST00000216029.7
ENST00000416285.5
chibby family member 1, beta catenin antagonist
chr7_+_129502517 31.24 ENST00000462322.3
small lysine rich protein 1
chr8_+_143716318 31.05 ENST00000338033.9
ENST00000395107.8
ENST00000395108.2
mitogen-activated protein kinase 15
chr5_-_55233586 30.94 ENST00000282572.5
cyclin O
chr21_-_39445719 30.88 ENST00000438404.5
ENST00000358268.6
ENST00000411566.5
ENST00000451131.1
ENST00000418018.5
ENST00000415863.5
ENST00000426783.5
ENST00000485895.6
ENST00000288350.8
ENST00000448288.6
ENST00000456017.5
ENST00000434281.5
lebercilin LCA5 like
chr1_+_63523490 30.82 ENST00000371088.5
EF-hand calcium binding domain 7
chr16_+_89657740 30.77 ENST00000566204.2
ENST00000301031.8
ENST00000579310.6
spermatogenesis associated 33
chr14_+_99793375 30.61 ENST00000262233.11
ENST00000556714.5
EMAP like 1
chr1_-_169367746 30.59 ENST00000367811.8
ENST00000472647.5
NME/NM23 family member 7
chr7_-_101321723 29.91 ENST00000498704.6
ENST00000517481.5
ENST00000437644.2
ENST00000315322.10
ENST00000621899.4
intraflagellar transport 22
chr12_+_6821797 29.78 ENST00000311268.8
ENST00000382315.7
G protein-coupled receptor 162
chr4_+_40749909 29.09 ENST00000316607.5
ENST00000381782.7
NOP2/Sun RNA methyltransferase family member 7
chr13_+_36431898 29.08 ENST00000440264.5
cyclin A1
chr1_-_24413717 29.06 ENST00000003583.12
ENST00000337248.9
sperm tail PG-rich repeat containing 1
chr10_+_102419189 29.02 ENST00000432590.5
F-box and leucine rich repeat protein 15
chr3_+_119703001 28.88 ENST00000273390.9
ENST00000463700.1
ENST00000648112.1
cilia and flagella associated protein 91
novel protein
chr7_-_130441136 28.86 ENST00000675596.1
ENST00000676312.1
centrosomal protein 41
chr16_-_67416420 28.52 ENST00000348579.6
ENST00000565726.3
zinc finger DHHC-type containing 1
chr2_-_177552781 28.41 ENST00000408939.4
tetratricopeptide repeat domain 30B
chr13_+_36432487 28.03 ENST00000255465.7
ENST00000625767.1
cyclin A1
chr11_-_75668434 27.70 ENST00000434603.2
microtubule associated protein 6
chr16_+_89657855 27.63 ENST00000564238.2
spermatogenesis associated 33
chr3_-_114056481 27.52 ENST00000295878.8
ENST00000483766.1
ENST00000491000.5
coiled-coil domain containing 191
chr7_+_134127299 27.27 ENST00000645682.1
ENST00000285928.2
leucine rich repeats and guanylate kinase domain containing
chr2_+_158795309 26.94 ENST00000309950.8
ENST00000621326.4
ENST00000409042.5
death associated protein like 1
chr1_-_48472007 26.92 ENST00000371843.7
spermatogenesis associated 6
chr12_-_62935117 26.78 ENST00000228705.7
protein phosphatase, Mg2+/Mn2+ dependent 1H
chr11_+_111937320 26.55 ENST00000440460.7
DIX domain containing 1
chr9_+_97307645 26.36 ENST00000529487.3
coiled-coil domain containing 180
chr11_-_8594140 26.08 ENST00000534493.5
ENST00000422559.6
serine/threonine kinase 33
chr5_-_14011743 26.00 ENST00000681290.1
dynein axonemal heavy chain 5
chr10_+_125896549 25.92 ENST00000368693.6
fibronectin type III and ankyrin repeat domains 1
chr16_+_3500964 25.68 ENST00000574369.5
ENST00000576634.6
ENST00000341633.9
ENST00000571025.5
clusterin associated protein 1
chr10_+_12349533 25.50 ENST00000619168.5
calcium/calmodulin dependent protein kinase ID
chr19_-_41364119 25.45 ENST00000243578.8
B9 domain containing 2
chr6_-_39725335 25.44 ENST00000538893.5
kinesin family member 6
chr19_-_55279690 25.37 ENST00000587959.1
ENST00000585927.1
ENST00000587922.5
ENST00000585698.1
HSPA (Hsp70) binding protein 1
chr19_-_50025936 25.24 ENST00000596445.5
ENST00000599538.5
VRK serine/threonine kinase 3
chr11_-_119381629 25.06 ENST00000260187.7
ENST00000455332.6
ubiquitin specific peptidase 2
chr2_+_108786738 24.90 ENST00000412964.6
ENST00000295124.9
coiled-coil domain containing 138
chr10_-_73358709 24.83 ENST00000340329.7
cilia and flagella associated protein 70
chr7_+_2558960 24.60 ENST00000623361.3
ENST00000402050.7
IQ motif containing E
chr11_+_17276708 24.59 ENST00000531172.5
ENST00000529010.6
ENST00000533738.6
ENST00000323688.10
nucleobindin 2
chr14_+_74019341 24.38 ENST00000394009.5
ENST00000464394.5
basal body orientation factor 1
chr10_-_73358853 24.34 ENST00000355577.8
ENST00000310715.7
cilia and flagella associated protein 70
chr7_+_107044689 24.16 ENST00000265717.5
protein kinase cAMP-dependent type II regulatory subunit beta
chr11_+_537517 24.14 ENST00000270115.8
leucine rich repeat containing 56
chr11_+_103109522 24.01 ENST00000334267.11
dynein cytoplasmic 2 heavy chain 1
chr2_-_229714478 23.95 ENST00000341772.5
delta/notch like EGF repeat containing
chr17_+_7857695 23.75 ENST00000571846.5
cytochrome b5 domain containing 1
chr16_+_57372465 23.67 ENST00000563383.1
C-X3-C motif chemokine ligand 1
chr19_+_35138993 23.59 ENST00000612146.4
ENST00000589209.5
FXYD domain containing ion transport regulator 1
chr19_-_55280063 23.50 ENST00000593263.5
ENST00000433386.7
HSPA (Hsp70) binding protein 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
24.7 889.0 GO:0044458 motile cilium assembly(GO:0044458)
21.3 85.2 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
20.0 60.1 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
15.8 47.4 GO:1904158 axonemal central apparatus assembly(GO:1904158)
14.6 87.6 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
13.1 105.1 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
13.0 38.9 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
11.3 147.2 GO:0060294 cilium movement involved in cell motility(GO:0060294)
11.0 32.9 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
10.6 31.7 GO:0031393 negative regulation of prostaglandin biosynthetic process(GO:0031393)
10.2 530.6 GO:0035082 axoneme assembly(GO:0035082)
8.1 24.4 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
6.8 47.6 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
6.7 20.2 GO:0006756 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
6.6 33.1 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
6.6 26.2 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
6.1 24.3 GO:0060285 cilium-dependent cell motility(GO:0060285)
5.7 51.4 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
5.6 67.7 GO:0035721 intraciliary retrograde transport(GO:0035721)
5.3 31.7 GO:0034499 late endosome to Golgi transport(GO:0034499)
5.0 90.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
5.0 258.9 GO:0042073 intraciliary transport(GO:0042073)
4.4 75.2 GO:0003341 cilium movement(GO:0003341)
3.7 18.7 GO:0001757 somite specification(GO:0001757)
3.7 26.1 GO:0070560 protein secretion by platelet(GO:0070560)
3.6 25.5 GO:0018095 protein polyglutamylation(GO:0018095)
3.6 32.2 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
3.5 10.4 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
3.1 24.6 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
2.9 103.6 GO:0002021 response to dietary excess(GO:0002021)
2.8 25.5 GO:0060267 positive regulation of respiratory burst(GO:0060267)
2.8 8.4 GO:0030573 bile acid catabolic process(GO:0030573)
2.7 11.0 GO:1903575 cornified envelope assembly(GO:1903575)
2.7 13.6 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
2.6 69.4 GO:0034389 lipid particle organization(GO:0034389)
2.5 9.9 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
2.4 123.7 GO:0001578 microtubule bundle formation(GO:0001578)
2.3 7.0 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
2.3 18.4 GO:0044375 regulation of peroxisome size(GO:0044375)
2.3 6.8 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
2.2 40.4 GO:0021670 lateral ventricle development(GO:0021670)
2.1 32.2 GO:0007258 JUN phosphorylation(GO:0007258)
2.1 68.4 GO:0071801 regulation of podosome assembly(GO:0071801)
2.1 24.8 GO:0003406 retinal pigment epithelium development(GO:0003406)
2.1 10.3 GO:1902612 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
2.0 6.1 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
2.0 10.2 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
2.0 6.0 GO:0051365 leading edge cell differentiation(GO:0035026) cellular response to potassium ion starvation(GO:0051365)
1.8 37.3 GO:1904355 positive regulation of telomere capping(GO:1904355)
1.7 17.3 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
1.7 32.4 GO:0006228 UTP biosynthetic process(GO:0006228)
1.7 28.4 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
1.7 33.4 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
1.7 5.0 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
1.7 26.5 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
1.6 19.6 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
1.6 29.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
1.6 25.1 GO:0045475 locomotor rhythm(GO:0045475)
1.6 4.7 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
1.5 57.1 GO:0007141 male meiosis I(GO:0007141)
1.5 13.5 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
1.5 22.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
1.4 47.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
1.4 10.0 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
1.4 23.9 GO:0007220 Notch receptor processing(GO:0007220)
1.4 4.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
1.4 80.8 GO:0007405 neuroblast proliferation(GO:0007405)
1.4 9.5 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
1.4 39.2 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
1.3 76.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
1.3 13.3 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
1.3 22.2 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
1.3 3.8 GO:1902269 putrescine transport(GO:0015847) positive regulation of polyamine transmembrane transport(GO:1902269)
1.3 116.0 GO:0021795 cerebral cortex cell migration(GO:0021795)
1.3 5.0 GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
1.2 286.4 GO:0060271 cilium morphogenesis(GO:0060271)
1.2 23.5 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
1.2 21.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
1.2 4.7 GO:0009956 radial pattern formation(GO:0009956) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
1.1 35.8 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
1.1 106.2 GO:0007368 determination of left/right symmetry(GO:0007368)
1.1 32.7 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
1.1 7.6 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
1.1 11.7 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
1.0 2.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
1.0 26.0 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
1.0 22.8 GO:0002115 store-operated calcium entry(GO:0002115)
1.0 6.1 GO:0038016 insulin receptor internalization(GO:0038016)
1.0 107.7 GO:0032418 lysosome localization(GO:0032418)
1.0 5.0 GO:0052173 response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572) response to host(GO:0075136)
1.0 7.9 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.9 9.7 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.8 28.5 GO:0018345 protein palmitoylation(GO:0018345)
0.8 113.0 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.8 2.5 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.8 32.9 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.8 11.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.8 4.0 GO:1902904 regulation of fibril organization(GO:1902903) negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.8 124.0 GO:0007286 spermatid development(GO:0007286)
0.7 6.0 GO:0072553 terminal button organization(GO:0072553)
0.7 2.1 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.7 11.1 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.7 8.0 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.6 16.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.6 16.1 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.6 24.8 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.6 13.9 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.6 2.4 GO:0018032 protein amidation(GO:0018032)
0.6 13.5 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.6 11.1 GO:0071539 protein localization to centrosome(GO:0071539)
0.6 17.3 GO:2001222 regulation of neuron migration(GO:2001222)
0.6 6.3 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.6 2.3 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344) homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.6 39.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.6 11.8 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.5 5.2 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.5 17.5 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.5 44.1 GO:0009060 aerobic respiration(GO:0009060)
0.5 7.4 GO:0001302 replicative cell aging(GO:0001302)
0.5 18.5 GO:0002437 inflammatory response to antigenic stimulus(GO:0002437)
0.5 26.1 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.4 3.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.4 4.0 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.4 19.9 GO:0006298 mismatch repair(GO:0006298)
0.4 8.6 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.4 16.4 GO:0035825 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.4 7.8 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.4 8.1 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.4 3.6 GO:0015886 heme transport(GO:0015886)
0.4 46.5 GO:0022900 electron transport chain(GO:0022900)
0.3 43.0 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.3 2.0 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.3 3.1 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.3 1.5 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.3 10.4 GO:0010107 potassium ion import(GO:0010107)
0.3 4.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.3 1.7 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.3 5.9 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.3 6.0 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.3 10.9 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.3 4.9 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.2 5.9 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.2 13.8 GO:0015701 bicarbonate transport(GO:0015701)
0.2 6.9 GO:0001975 response to amphetamine(GO:0001975)
0.2 2.8 GO:0070933 histone H4 deacetylation(GO:0070933)
0.2 10.3 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.2 7.7 GO:0035357 peroxisome proliferator activated receptor signaling pathway(GO:0035357)
0.2 4.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.2 82.8 GO:0007283 spermatogenesis(GO:0007283)
0.2 7.2 GO:0006379 mRNA cleavage(GO:0006379)
0.2 0.3 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.2 1.5 GO:0032264 IMP salvage(GO:0032264)
0.2 14.9 GO:0090630 activation of GTPase activity(GO:0090630)
0.2 2.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 1.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 5.1 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 6.6 GO:0048255 mRNA stabilization(GO:0048255)
0.1 0.6 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 4.2 GO:0016578 histone deubiquitination(GO:0016578)
0.1 5.9 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.1 4.3 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.1 2.5 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.1 2.6 GO:0006004 fucose metabolic process(GO:0006004)
0.1 4.6 GO:0008038 neuron recognition(GO:0008038)
0.1 3.5 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.1 2.7 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 2.9 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 19.7 GO:0045444 fat cell differentiation(GO:0045444)
0.1 11.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 2.2 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.6 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 3.6 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.1 2.5 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 3.4 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 4.3 GO:0015914 phospholipid transport(GO:0015914)
0.0 25.0 GO:0043687 post-translational protein modification(GO:0043687)
0.0 1.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.1 GO:0035902 response to immobilization stress(GO:0035902)
0.0 3.6 GO:0007098 centrosome cycle(GO:0007098)
0.0 2.2 GO:0045453 bone resorption(GO:0045453)
0.0 6.7 GO:1901796 regulation of signal transduction by p53 class mediator(GO:1901796)
0.0 2.5 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 1.4 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 3.7 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.3 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.2 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.8 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.2 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 1.4 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 1.1 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.2 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
39.8 278.8 GO:0002177 manchette(GO:0002177)
27.9 83.8 GO:0001534 radial spoke(GO:0001534)
22.7 68.0 GO:0097224 sperm connecting piece(GO:0097224)
22.6 225.9 GO:0072687 meiotic spindle(GO:0072687)
21.0 63.1 GO:1990716 axonemal central apparatus(GO:1990716)
15.9 158.6 GO:0005879 axonemal microtubule(GO:0005879)
14.3 57.1 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
11.3 349.1 GO:0030992 intraciliary transport particle B(GO:0030992)
10.3 123.7 GO:0097427 microtubule bundle(GO:0097427)
9.3 213.0 GO:0036038 MKS complex(GO:0036038)
8.7 17.4 GO:0097545 axonemal outer doublet(GO:0097545)
8.1 16.2 GO:0016939 kinesin II complex(GO:0016939)
7.6 91.3 GO:0034464 BBSome(GO:0034464)
7.4 110.5 GO:1990023 mitotic spindle midzone(GO:1990023)
6.5 659.3 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
6.4 31.9 GO:1990769 proximal neuron projection(GO:1990769)
5.7 237.5 GO:0034451 centriolar satellite(GO:0034451)
5.6 27.9 GO:0043291 RAVE complex(GO:0043291)
4.6 69.4 GO:0001520 outer dense fiber(GO:0001520)
4.6 95.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
3.5 41.5 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
3.0 33.4 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
3.0 3.0 GO:0002199 zona pellucida receptor complex(GO:0002199)
2.3 13.6 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
2.1 18.7 GO:0044294 dendritic growth cone(GO:0044294)
2.1 10.4 GO:1990761 growth cone lamellipodium(GO:1990761)
2.0 5.9 GO:0033565 ESCRT-0 complex(GO:0033565)
1.9 109.6 GO:0009925 basal plasma membrane(GO:0009925)
1.8 124.9 GO:0005801 cis-Golgi network(GO:0005801)
1.7 32.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
1.6 32.9 GO:0032391 photoreceptor connecting cilium(GO:0032391)
1.6 44.5 GO:0071682 endocytic vesicle lumen(GO:0071682)
1.6 25.2 GO:0001673 male germ cell nucleus(GO:0001673)
1.5 810.5 GO:0005929 cilium(GO:0005929)
1.5 9.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
1.4 16.3 GO:0000242 pericentriolar material(GO:0000242)
1.4 9.5 GO:0000138 Golgi trans cisterna(GO:0000138)
1.3 148.6 GO:0001669 acrosomal vesicle(GO:0001669)
1.2 26.1 GO:0031095 spectrin-associated cytoskeleton(GO:0014731) platelet dense tubular network membrane(GO:0031095)
1.2 105.1 GO:0005814 centriole(GO:0005814)
1.1 68.4 GO:0002102 podosome(GO:0002102)
1.1 19.0 GO:0035102 PRC1 complex(GO:0035102)
1.0 12.9 GO:0072546 ER membrane protein complex(GO:0072546)
1.0 10.8 GO:0000137 Golgi cis cisterna(GO:0000137)
0.9 19.5 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.9 6.8 GO:0043196 varicosity(GO:0043196)
0.8 6.0 GO:0035976 AP1 complex(GO:0035976)
0.7 52.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.7 57.5 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.6 308.4 GO:0005874 microtubule(GO:0005874)
0.6 6.3 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.6 18.4 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.5 26.2 GO:0016235 aggresome(GO:0016235)
0.5 24.6 GO:0035861 site of double-strand break(GO:0035861)
0.5 4.0 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.5 3.5 GO:0070847 core mediator complex(GO:0070847)
0.5 11.0 GO:0031201 SNARE complex(GO:0031201)
0.4 3.4 GO:0097451 astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451)
0.4 5.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.4 4.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.4 4.9 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.4 143.6 GO:0005813 centrosome(GO:0005813)
0.4 6.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.4 17.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.4 4.3 GO:0017119 Golgi transport complex(GO:0017119)
0.4 9.3 GO:0000421 autophagosome membrane(GO:0000421)
0.3 61.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.3 35.6 GO:1902911 protein kinase complex(GO:1902911)
0.3 67.9 GO:0005802 trans-Golgi network(GO:0005802)
0.3 4.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.3 33.5 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.2 17.7 GO:0005901 caveola(GO:0005901)
0.2 7.7 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.2 7.9 GO:0016514 SWI/SNF complex(GO:0016514)
0.2 3.1 GO:0031143 pseudopodium(GO:0031143)
0.2 143.7 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 1.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 9.5 GO:0015030 Cajal body(GO:0015030)
0.1 7.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 4.9 GO:1904115 axon cytoplasm(GO:1904115)
0.1 7.1 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 2.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 9.5 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 8.5 GO:0032587 ruffle membrane(GO:0032587)
0.1 10.9 GO:0030426 growth cone(GO:0030426)
0.1 1.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 6.8 GO:0055037 recycling endosome(GO:0055037)
0.1 4.6 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 10.2 GO:0001650 fibrillar center(GO:0001650)
0.1 6.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 3.0 GO:0030496 midbody(GO:0030496)
0.0 3.8 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 1.1 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 14.1 GO:0005635 nuclear envelope(GO:0005635)
0.0 13.9 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 17.0 GO:0009986 cell surface(GO:0009986)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
18.7 37.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
13.5 40.4 GO:0031862 prostanoid receptor binding(GO:0031862)
13.4 13.4 GO:0005119 smoothened binding(GO:0005119)
11.9 35.8 GO:0030156 benzodiazepine receptor binding(GO:0030156)
9.1 36.5 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
7.9 31.7 GO:0005136 interleukin-4 receptor binding(GO:0005136)
7.6 106.2 GO:0045504 dynein heavy chain binding(GO:0045504)
6.7 33.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
6.2 68.0 GO:0032027 myosin light chain binding(GO:0032027)
6.1 48.6 GO:0008158 hedgehog receptor activity(GO:0008158)
4.8 144.7 GO:0017160 Ral GTPase binding(GO:0017160)
4.3 39.0 GO:0003777 microtubule motor activity(GO:0003777)
4.3 30.0 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
3.9 78.9 GO:0045503 dynein light chain binding(GO:0045503)
3.8 15.2 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
3.4 10.3 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
3.4 13.5 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
3.3 19.6 GO:0061649 ubiquitinated histone binding(GO:0061649)
3.2 90.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
3.2 47.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
3.1 12.6 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
3.1 30.9 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
2.9 132.5 GO:0043015 gamma-tubulin binding(GO:0043015)
2.8 33.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
2.6 23.5 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
2.5 32.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
2.2 8.6 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
2.1 19.1 GO:0045505 dynein intermediate chain binding(GO:0045505)
2.0 6.1 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
2.0 22.3 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
1.8 62.9 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
1.7 36.6 GO:0034452 dynactin binding(GO:0034452)
1.7 72.6 GO:0070840 dynein complex binding(GO:0070840)
1.7 6.9 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
1.6 16.2 GO:0004565 beta-galactosidase activity(GO:0004565)
1.6 87.7 GO:0030544 Hsp70 protein binding(GO:0030544)
1.5 13.6 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
1.5 29.4 GO:0004707 MAP kinase activity(GO:0004707)
1.4 5.7 GO:0002046 opsin binding(GO:0002046)
1.4 26.9 GO:0070513 death domain binding(GO:0070513)
1.3 490.6 GO:0008017 microtubule binding(GO:0008017)
1.3 60.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
1.3 3.8 GO:0015489 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
1.3 10.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
1.2 47.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
1.2 76.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
1.2 9.7 GO:0004673 phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673)
1.1 25.1 GO:0030332 cyclin binding(GO:0030332)
1.1 11.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
1.0 3.1 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
1.0 90.0 GO:0015631 tubulin binding(GO:0015631)
1.0 12.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
1.0 8.0 GO:0019826 oxygen sensor activity(GO:0019826)
1.0 61.8 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
1.0 23.9 GO:0005112 Notch binding(GO:0005112)
0.9 15.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.9 56.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.9 41.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.8 2.5 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.8 28.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.8 6.1 GO:0015235 cobalamin transporter activity(GO:0015235)
0.7 6.0 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.7 8.0 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.7 28.4 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.7 2.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.7 2.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.7 9.6 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.7 19.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.7 19.9 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.7 93.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.7 13.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.6 91.5 GO:0005254 chloride channel activity(GO:0005254)
0.6 10.2 GO:0048156 tau protein binding(GO:0048156)
0.6 57.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.6 38.7 GO:0030331 estrogen receptor binding(GO:0030331)
0.6 39.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.5 10.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.5 4.7 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.5 8.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.5 4.9 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.5 4.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.4 11.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.4 415.7 GO:0005509 calcium ion binding(GO:0005509)
0.4 2.5 GO:0004966 galanin receptor activity(GO:0004966)
0.4 3.6 GO:0015232 heme transporter activity(GO:0015232)
0.4 1.6 GO:0032406 purine-specific mismatch base pair DNA N-glycosylase activity(GO:0000701) MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.4 17.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.4 6.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.3 163.9 GO:0005525 GTP binding(GO:0005525)
0.3 4.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.3 9.9 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.3 5.0 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.3 32.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.3 2.5 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.3 10.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.3 1.5 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.3 6.0 GO:0035497 cAMP response element binding(GO:0035497)
0.3 6.8 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.3 8.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.3 32.9 GO:0019887 protein kinase regulator activity(GO:0019887)
0.2 8.4 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.2 2.0 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 20.6 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.2 22.9 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)
0.2 33.4 GO:0017137 Rab GTPase binding(GO:0017137)
0.2 84.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.2 0.3 GO:0035514 DNA demethylase activity(GO:0035514)
0.2 7.1 GO:0035064 methylated histone binding(GO:0035064)
0.2 8.7 GO:0030507 spectrin binding(GO:0030507)
0.1 8.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 4.7 GO:0001972 retinoic acid binding(GO:0001972)
0.1 3.7 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 14.7 GO:0043130 ubiquitin binding(GO:0043130)
0.1 7.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.0 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 7.5 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.1 7.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 1.1 GO:0016594 glycine binding(GO:0016594)
0.1 33.0 GO:0004857 enzyme inhibitor activity(GO:0004857)
0.1 2.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 3.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 7.5 GO:0016279 protein-lysine N-methyltransferase activity(GO:0016279)
0.1 5.5 GO:0008013 beta-catenin binding(GO:0008013)
0.1 5.0 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 7.1 GO:0051082 unfolded protein binding(GO:0051082)
0.1 0.6 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 206.3 GO:0003677 DNA binding(GO:0003677)
0.1 1.6 GO:0071949 FAD binding(GO:0071949)
0.1 0.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 1.0 GO:0005537 mannose binding(GO:0005537)
0.1 3.5 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.1 0.2 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1 1.0 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.1 5.0 GO:0005518 collagen binding(GO:0005518)
0.0 1.2 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.2 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 2.1 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.7 GO:0003774 motor activity(GO:0003774)
0.0 0.2 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 4.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 5.5 GO:0017111 nucleoside-triphosphatase activity(GO:0017111)
0.0 1.1 GO:0042393 histone binding(GO:0042393)
0.0 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 2.1 GO:0004518 nuclease activity(GO:0004518)
0.0 1.6 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 8.8 GO:0005198 structural molecule activity(GO:0005198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 50.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.9 68.4 PID PLK1 PATHWAY PLK1 signaling events
0.7 38.3 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.5 31.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.5 10.3 PID ALK2 PATHWAY ALK2 signaling events
0.4 17.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.3 8.0 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.3 30.2 PID NOTCH PATHWAY Notch signaling pathway
0.3 22.6 PID TNF PATHWAY TNF receptor signaling pathway
0.2 25.4 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.2 10.8 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.2 11.8 PID ARF6 PATHWAY Arf6 signaling events
0.2 9.2 PID ATM PATHWAY ATM pathway
0.2 43.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.2 6.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.2 13.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 6.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.2 1.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.2 11.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.2 10.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 6.6 PID P53 REGULATION PATHWAY p53 pathway
0.1 2.5 PID CD40 PATHWAY CD40/CD40L signaling
0.1 10.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 5.9 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 5.5 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 3.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 4.0 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.1 18.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.3 PID TELOMERASE PATHWAY Regulation of Telomerase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 57.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
1.6 32.5 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
1.5 24.6 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
1.4 28.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
1.4 38.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.9 60.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.8 80.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.6 8.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.6 5.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.5 8.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.4 27.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.4 11.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.4 13.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.3 9.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.3 6.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.3 9.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.3 10.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 5.9 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.2 8.3 REACTOME KINESINS Genes involved in Kinesins
0.2 8.0 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 9.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 18.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.2 5.9 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.2 20.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 8.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.2 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.1 2.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 7.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 2.6 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 7.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.0 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 12.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 2.5 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.7 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 4.0 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 1.9 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.5 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 17.1 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 2.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 3.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 1.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors