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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for RREB1

Z-value: 1.14

Motif logo

Transcription factors associated with RREB1

Gene Symbol Gene ID Gene Info
ENSG00000124782.20 RREB1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RREB1hg38_v1_chr6_+_7107941_71080310.328.8e-02Click!

Activity profile of RREB1 motif

Sorted Z-values of RREB1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RREB1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_-_50968125 10.03 ENST00000594641.1
kallikrein related peptidase 6
chr19_-_50953063 6.62 ENST00000391809.6
kallikrein related peptidase 5
chr19_-_50953093 6.59 ENST00000593428.5
kallikrein related peptidase 5
chr19_-_50952942 6.57 ENST00000594846.1
ENST00000336334.8
kallikrein related peptidase 5
chr6_+_151325665 5.85 ENST00000354675.10
A-kinase anchoring protein 12
chr18_-_23662810 4.57 ENST00000322980.13
ankyrin repeat domain 29
chr4_+_74365136 4.19 ENST00000244869.3
epiregulin
chr4_+_8229170 3.54 ENST00000511002.6
SH3 domain and tetratricopeptide repeats 1
chr18_-_23662868 3.51 ENST00000586087.1
ENST00000592179.6
ankyrin repeat domain 29
chr2_+_233195433 3.41 ENST00000417661.1
inositol polyphosphate-5-phosphatase D
chr10_+_17229267 3.18 ENST00000224237.9
vimentin
chr19_-_18941117 3.00 ENST00000600077.5
homer scaffold protein 3
chr12_-_121793668 2.86 ENST00000267205.7
ras homolog family member F, filopodia associated
chr17_+_64449037 2.72 ENST00000615220.4
ENST00000619286.5
ENST00000612535.4
ENST00000616498.4
mast cell immunoglobulin like receptor 1
chr1_-_16980607 2.69 ENST00000375535.4
microfibril associated protein 2
chr9_+_128411715 2.51 ENST00000420034.5
ENST00000372842.5
cerebral endothelial cell adhesion molecule
chr19_-_18941184 2.51 ENST00000594794.5
ENST00000392351.8
ENST00000596482.5
homer scaffold protein 3
chr8_+_32548303 2.44 ENST00000650967.1
neuregulin 1
chr16_+_397209 2.40 ENST00000382940.8
NME/NM23 nucleoside diphosphate kinase 4
chr16_-_4538819 2.31 ENST00000564828.5
cell death inducing p53 target 1
chr8_+_32548210 2.29 ENST00000523079.5
ENST00000650919.1
neuregulin 1
chrX_+_17737443 2.21 ENST00000398080.5
ENST00000380045.7
ENST00000380043.7
ENST00000380041.8
Scm polycomb group protein like 1
chr16_+_58500047 2.19 ENST00000566192.5
ENST00000565088.5
ENST00000568640.5
NDRG family member 4
chr5_+_151212117 2.17 ENST00000523466.5
GM2 ganglioside activator
chr16_-_4538761 2.14 ENST00000567695.6
ENST00000562334.5
ENST00000562579.5
ENST00000563507.5
cell death inducing p53 target 1
chr16_-_4538469 2.09 ENST00000588381.1
ENST00000563332.6
cell death inducing p53 target 1
chr16_+_397226 2.01 ENST00000433358.5
NME/NM23 nucleoside diphosphate kinase 4
chr16_+_58500135 2.00 ENST00000563978.5
ENST00000569923.5
ENST00000356752.8
ENST00000563799.5
ENST00000562999.5
ENST00000570248.5
ENST00000562731.5
ENST00000568424.1
NDRG family member 4
chr18_+_36297661 1.88 ENST00000257209.8
ENST00000590592.5
ENST00000359247.8
formin homology 2 domain containing 3
chr10_-_99235783 1.87 ENST00000370546.5
ENST00000614306.1
heparanase 2 (inactive)
chr7_-_24757413 1.80 ENST00000645220.1
ENST00000409970.6
gasdermin E
chr10_-_3785225 1.76 ENST00000542957.1
Kruppel like factor 6
chr12_-_52680398 1.75 ENST00000252244.3
keratin 1
chr10_-_3785197 1.70 ENST00000497571.6
Kruppel like factor 6
chr7_-_128405930 1.67 ENST00000470772.5
ENST00000480861.5
ENST00000496200.5
inosine monophosphate dehydrogenase 1
chr2_-_85410336 1.67 ENST00000263867.9
ENST00000409921.5
capping actin protein, gelsolin like
chr19_-_50719761 1.60 ENST00000293441.6
SH3 and multiple ankyrin repeat domains 1
chr1_+_65525641 1.53 ENST00000344610.12
ENST00000616738.4
leptin receptor
chr19_-_38735405 1.53 ENST00000597987.5
ENST00000595177.1
calpain 12
chr16_+_397183 1.51 ENST00000620944.4
ENST00000621774.4
ENST00000219479.7
NME/NM23 nucleoside diphosphate kinase 4
chr9_-_104928139 1.51 ENST00000423487.6
ENST00000374733.1
ENST00000374736.8
ENST00000678995.1
ATP binding cassette subfamily A member 1
chr17_-_41060109 1.51 ENST00000391418.3
keratin associated protein 2-3
chrX_+_135032346 1.48 ENST00000257013.9
retrotransposon Gag like 8C
chr21_+_36135071 1.47 ENST00000290354.6
carbonyl reductase 3
chr17_-_41481140 1.44 ENST00000246639.6
ENST00000393989.1
keratin 35
chr2_+_28395511 1.42 ENST00000436647.1
FOS like 2, AP-1 transcription factor subunit
chr18_+_74499939 1.42 ENST00000584768.5
carnosine dipeptidase 2
chr12_-_119803383 1.40 ENST00000392520.2
ENST00000678677.1
ENST00000679249.1
ENST00000676849.1
citron rho-interacting serine/threonine kinase
chr1_-_228416841 1.40 ENST00000366698.7
ENST00000457345.2
tripartite motif containing 17
chr12_-_7936177 1.37 ENST00000544291.1
ENST00000075120.12
solute carrier family 2 member 3
chr9_+_35906179 1.37 ENST00000354323.3
histidine rich carboxyl terminus 1
chr3_-_42702778 1.32 ENST00000457462.5
ENST00000441594.6
hedgehog acyltransferase like
chr20_-_38165261 1.32 ENST00000361475.7
transglutaminase 2
chr3_-_169769542 1.26 ENST00000330368.3
actin related protein T3
chr10_-_33335074 1.23 ENST00000432372.6
neuropilin 1
chr1_-_228416626 1.22 ENST00000355586.4
ENST00000520264.1
ENST00000479800.1
ENST00000295033.7
tripartite motif containing 17
chr8_+_32548267 1.21 ENST00000356819.7
neuregulin 1
chr14_+_104689588 1.19 ENST00000330634.11
ENST00000392634.9
ENST00000675482.1
ENST00000398337.8
inverted formin 2
chr12_-_94650506 1.17 ENST00000261226.9
transmembrane and coiled-coil domain family 3
chr19_-_14112641 1.15 ENST00000536649.5
protein kinase cAMP-activated catalytic subunit alpha
chr1_-_161223559 1.12 ENST00000469730.2
ENST00000463273.5
ENST00000464492.5
ENST00000367990.7
ENST00000470459.6
ENST00000463812.1
ENST00000468465.5
apolipoprotein A2
chr20_+_43667019 1.11 ENST00000396863.8
MYB proto-oncogene like 2
chr15_+_63189554 1.10 ENST00000559006.1
ENST00000321437.9
RAB8B, member RAS oncogene family
chr3_+_155080088 1.10 ENST00000462745.5
membrane metalloendopeptidase
chr17_-_75844334 1.08 ENST00000592386.5
ENST00000412096.6
ENST00000586147.1
ENST00000207549.9
unc-13 homolog D
chr10_-_33334898 1.06 ENST00000395995.5
neuropilin 1
chr10_-_3785179 1.05 ENST00000469435.1
Kruppel like factor 6
chr12_+_26195647 1.05 ENST00000535504.1
sarcospan
chr10_-_33334625 1.04 ENST00000374875.5
ENST00000374822.8
ENST00000374867.7
neuropilin 1
chr20_+_43667105 1.03 ENST00000217026.5
MYB proto-oncogene like 2
chr3_+_155079847 1.00 ENST00000615825.2
membrane metalloendopeptidase
chr8_-_143541425 0.99 ENST00000262577.6
zinc finger CCCH-type containing 3
chr22_-_35961623 0.98 ENST00000408983.2
RNA binding fox-1 homolog 2
chr11_+_847197 0.94 ENST00000532375.5
ENST00000346501.8
tetraspanin 4
chr17_-_41065879 0.93 ENST00000394015.3
keratin associated protein 2-4
chrX_-_132218124 0.93 ENST00000342983.6
RAP2C, member of RAS oncogene family
chr1_+_101238090 0.92 ENST00000475289.2
sphingosine-1-phosphate receptor 1
chr17_+_60422483 0.92 ENST00000269127.5
chromosome 17 open reading frame 64
chr1_+_109548567 0.91 ENST00000369851.7
G protein subunit alpha i3
chrX_+_154585120 0.89 ENST00000593606.3
ENST00000599837.3
cancer/testis antigen 1A
chr21_-_46228751 0.89 ENST00000450351.1
ENST00000397728.8
ENST00000522411.5
ENST00000356396.8
ENST00000457828.6
lanosterol synthase
chr16_+_28878480 0.87 ENST00000395503.9
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr11_-_59668981 0.86 ENST00000300146.10
PAT1 homolog 1, processing body mRNA decay factor
chr10_-_119596954 0.86 ENST00000436547.7
TIA1 cytotoxic granule associated RNA binding protein like 1
chr5_-_151924824 0.85 ENST00000455880.2
glycine receptor alpha 1
chr17_+_2055094 0.84 ENST00000399849.4
ENST00000619757.5
HIC ZBTB transcriptional repressor 1
chr3_-_195909711 0.83 ENST00000333602.14
tyrosine kinase non receptor 2
chr3_+_155079663 0.83 ENST00000460393.6
membrane metalloendopeptidase
chr10_-_99235846 0.83 ENST00000370552.8
ENST00000370549.5
ENST00000628193.2
heparanase 2 (inactive)
chrX_-_154619282 0.82 ENST00000328435.3
ENST00000359887.4
cancer/testis antigen 1B
chr8_+_26291758 0.82 ENST00000522535.5
ENST00000665949.1
protein phosphatase 2 regulatory subunit Balpha
chr17_+_40318237 0.82 ENST00000394089.6
ENST00000425707.7
retinoic acid receptor alpha
chr8_+_32548590 0.81 ENST00000652588.1
ENST00000521670.5
ENST00000287842.7
neuregulin 1
chr3_+_155079911 0.81 ENST00000675418.2
membrane metalloendopeptidase
chr15_-_89221558 0.80 ENST00000268125.10
retinaldehyde binding protein 1
chr18_-_46559289 0.80 ENST00000419859.1
ENST00000582408.6
ENST00000300591.11
lipoxygenase homology domains 1
chr5_-_142686079 0.79 ENST00000337706.7
fibroblast growth factor 1
chr2_+_227472363 0.78 ENST00000409315.5
ENST00000373671.7
ENST00000409171.5
ArfGAP with FG repeats 1
chr16_+_27313879 0.78 ENST00000562142.5
ENST00000561742.5
ENST00000543915.6
ENST00000395762.7
ENST00000563002.5
interleukin 4 receptor
chr17_+_60421697 0.78 ENST00000474834.5
chromosome 17 open reading frame 64
chr12_-_120250145 0.78 ENST00000458477.6
paxillin
chr16_+_28878382 0.75 ENST00000357084.7
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr2_-_32011001 0.74 ENST00000404530.6
mediator of cell motility 1
chr4_+_146638890 0.73 ENST00000281321.3
POU class 4 homeobox 2
chr7_-_712437 0.72 ENST00000360274.8
protein kinase cAMP-dependent type I regulatory subunit beta
chr3_-_39154558 0.71 ENST00000514182.1
cysteine and serine rich nuclear protein 1
chr12_+_6444932 0.71 ENST00000266557.4
CD27 molecule
chr8_-_59119121 0.70 ENST00000361421.2
thymocyte selection associated high mobility group box
chr12_-_12562344 0.70 ENST00000228862.3
dual specificity phosphatase 16
chr20_+_59604527 0.68 ENST00000371015.6
phosphatase and actin regulator 3
chr1_-_155978144 0.68 ENST00000313695.11
ENST00000497907.5
Rho/Rac guanine nucleotide exchange factor 2
chr12_+_56021316 0.68 ENST00000547791.2
IKAROS family zinc finger 4
chrX_+_47223009 0.68 ENST00000518022.5
ENST00000276052.10
cyclin dependent kinase 16
chrX_-_126166273 0.67 ENST00000360028.4
DDB1 and CUL4 associated factor 12 like 2
chr8_+_32548661 0.66 ENST00000650980.1
ENST00000405005.7
neuregulin 1
chr22_-_37580075 0.65 ENST00000215886.6
galectin 2
chr19_-_40714641 0.63 ENST00000678467.1
coenzyme Q8B
chr17_-_33293247 0.63 ENST00000225823.7
acid sensing ion channel subunit 2
chr20_+_49982969 0.62 ENST00000244050.3
snail family transcriptional repressor 1
chr12_+_6828377 0.62 ENST00000290510.10
prolyl 3-hydroxylase 3
chrX_-_13734575 0.62 ENST00000519885.5
ENST00000458511.7
ENST00000380579.6
ENST00000683983.1
ENST00000683569.1
ENST00000359680.9
trafficking protein particle complex 2
chr2_-_100417608 0.62 ENST00000264249.8
carbohydrate sulfotransferase 10
chr11_+_128693887 0.61 ENST00000281428.12
Fli-1 proto-oncogene, ETS transcription factor
chr20_+_833781 0.58 ENST00000381939.1
family with sequence similarity 110 member A
chr7_-_3043838 0.57 ENST00000356408.3
ENST00000396946.9
caspase recruitment domain family member 11
chr18_+_33578213 0.57 ENST00000681521.1
ENST00000269197.12
ASXL transcriptional regulator 3
chr12_+_118016690 0.57 ENST00000537315.5
ENST00000454402.7
ENST00000484086.6
ENST00000420967.5
ENST00000392542.6
ENST00000535092.1
replication factor C subunit 5
chr8_+_38404363 0.57 ENST00000527175.1
leucine zipper and EF-hand containing transmembrane protein 2
chr12_+_62260338 0.57 ENST00000353364.7
ENST00000549523.5
ubiquitin specific peptidase 15
chrX_-_120115909 0.56 ENST00000217999.3
Rhox homeobox family member 1
chrX_+_103330206 0.55 ENST00000372666.1
ENST00000332431.5
transcription elongation factor A like 7
chr19_+_40467145 0.55 ENST00000338932.7
spectrin beta, non-erythrocytic 4
chr17_+_79778135 0.54 ENST00000310942.9
ENST00000269399.5
chromobox 2
chr12_+_26195543 0.54 ENST00000242729.7
sarcospan
chr3_+_141487008 0.53 ENST00000286364.9
ENST00000452898.2
RAS p21 protein activator 2
chr2_-_53859929 0.53 ENST00000394705.3
ENST00000406625.6
G protein-coupled receptor 75
ankyrin repeat and SOCS box containing 3
chr16_+_21158653 0.51 ENST00000572258.5
ENST00000233047.9
ENST00000261388.7
ENST00000451578.6
ENST00000572599.5
ENST00000577162.1
transmembrane protein 159
chr4_-_95548956 0.51 ENST00000513796.5
ENST00000453304.6
unc-5 netrin receptor C
chr12_+_26195313 0.51 ENST00000422622.3
sarcospan
chr3_+_8733779 0.50 ENST00000343849.3
ENST00000397368.2
caveolin 3
chr12_-_57547121 0.50 ENST00000550954.5
ENST00000434715.7
ENST00000678505.1
ENST00000543672.6
ENST00000546670.5
ENST00000548249.6
dynactin subunit 2
chr21_-_34887148 0.50 ENST00000399240.5
RUNX family transcription factor 1
chr13_-_74133892 0.49 ENST00000377669.7
Kruppel like factor 12
chr12_-_12562851 0.49 ENST00000298573.9
dual specificity phosphatase 16
chr19_-_50833187 0.49 ENST00000598673.1
kallikrein related peptidase 15
chr12_-_57547224 0.48 ENST00000678322.1
dynactin subunit 2
chr7_-_92836555 0.48 ENST00000424848.3
cyclin dependent kinase 6
chr10_-_73655984 0.48 ENST00000394810.3
synaptopodin 2 like
chr8_+_143734133 0.47 ENST00000527139.7
ENST00000533004.5
IQ motif and ankyrin repeat containing 1
chr17_-_7179544 0.47 ENST00000619926.4
asialoglycoprotein receptor 1
chr1_-_153613095 0.47 ENST00000368706.9
S100 calcium binding protein A16
chr16_+_28823212 0.47 ENST00000570200.5
ataxin 2 like
chr17_-_45425620 0.47 ENST00000376922.6
Rho GTPase activating protein 27
chr16_+_68737284 0.46 ENST00000261769.10
ENST00000422392.6
cadherin 1
chr16_+_28822982 0.46 ENST00000336783.9
ENST00000340394.12
ENST00000325215.10
ENST00000382686.8
ENST00000395547.6
ENST00000564304.5
ataxin 2 like
chr19_+_35118456 0.45 ENST00000604621.5
FXYD domain containing ion transport regulator 3
chr8_+_89902529 0.45 ENST00000451899.7
oxidative stress induced growth inhibitor family member 2
chr17_-_7179348 0.45 ENST00000573083.1
ENST00000574388.5
ENST00000269299.8
asialoglycoprotein receptor 1
chr22_-_32205001 0.44 ENST00000652607.1
ret finger protein like 2
chr2_+_241637612 0.44 ENST00000625810.2
ENST00000402096.5
autophagy related 4B cysteine peptidase
chr19_+_54965252 0.44 ENST00000543010.5
ENST00000391721.8
ENST00000339757.11
NLR family pyrin domain containing 2
chr19_+_54966343 0.43 ENST00000537859.5
ENST00000585500.5
ENST00000427260.6
ENST00000448584.7
ENST00000263437.10
NLR family pyrin domain containing 2
chr9_-_34126661 0.43 ENST00000361264.9
DDB1 and CUL4 associated factor 12
chr20_+_836052 0.43 ENST00000246100.3
family with sequence similarity 110 member A
chr5_-_78294656 0.42 ENST00000519295.5
ENST00000255194.11
adaptor related protein complex 3 subunit beta 1
chr6_+_7107597 0.42 ENST00000379933.7
ENST00000491191.5
ENST00000471433.5
ras responsive element binding protein 1
chr11_-_72080389 0.41 ENST00000351960.10
ENST00000541719.5
ENST00000535111.5
nuclear mitotic apparatus protein 1
chr3_-_179072205 0.41 ENST00000432729.5
zinc finger matrin-type 3
chr12_+_48818478 0.41 ENST00000547818.5
ENST00000301050.7
ENST00000547392.5
calcium voltage-gated channel auxiliary subunit beta 3
chr9_-_21994345 0.41 ENST00000579755.2
ENST00000530628.2
cyclin dependent kinase inhibitor 2A
chr3_-_116444983 0.41 ENST00000333617.8
limbic system associated membrane protein
chr15_+_75206398 0.41 ENST00000565074.1
chromosome 15 open reading frame 39
chr10_+_68332090 0.40 ENST00000354695.5
heterogeneous nuclear ribonucleoprotein H3
chrX_-_152733715 0.39 ENST00000452779.3
ENST00000370287.7
chondrosarcoma associated gene 1
chr12_+_118981531 0.38 ENST00000267260.5
serine/arginine repetitive matrix 4
chr19_+_48364361 0.38 ENST00000344846.7
synaptogyrin 4
chr6_+_37354046 0.38 ENST00000487950.1
ENST00000469731.5
ring finger protein 8
chr2_-_136116165 0.38 ENST00000409817.1
C-X-C motif chemokine receptor 4
chr11_-_72080472 0.38 ENST00000537217.5
ENST00000366394.7
ENST00000358965.10
ENST00000546131.1
ENST00000393695.8
ENST00000543937.5
ENST00000368959.9
ENST00000541641.5
nuclear mitotic apparatus protein 1
chr2_+_120735848 0.38 ENST00000361492.9
GLI family zinc finger 2
chr6_+_112054075 0.37 ENST00000230529.9
ENST00000604763.5
ENST00000368666.7
ENST00000674325.1
ENST00000483439.1
ENST00000409166.5
cellular communication network factor 6
chr10_-_24723185 0.37 ENST00000376410.7
ENST00000446003.5
Rho GTPase activating protein 21
chr12_+_65824403 0.37 ENST00000393578.7
ENST00000425208.6
ENST00000536545.5
ENST00000354636.7
high mobility group AT-hook 2
chr19_-_15449920 0.37 ENST00000263381.12
ENST00000643092.1
ENST00000673675.1
WIZ zinc finger
chr19_-_56840661 0.36 ENST00000649735.1
ENST00000593695.5
ENST00000599577.5
ENST00000594389.1
ENST00000648694.1
ENST00000326441.15
ENST00000649680.1
ENST00000649876.1
ENST00000650632.1
ENST00000650102.1
ENST00000647621.1
ENST00000598410.5
ENST00000649233.1
ENST00000593711.6
ENST00000629319.2
ENST00000599935.5
paternally expressed 3
zinc finger imprinted 2
chr12_+_62260374 0.36 ENST00000312635.10
ENST00000280377.10
ENST00000549237.5
ubiquitin specific peptidase 15
chrX_-_152769677 0.35 ENST00000457643.1
ENST00000616035.4
ENST00000412733.1
ENST00000329342.9
MAGE family member A6
chr3_+_57060658 0.35 ENST00000334325.2
spermatogenesis associated 12
chr4_+_55853639 0.35 ENST00000381295.7
ENST00000346134.11
ENST00000349598.6
exocyst complex component 1
chr16_-_1225257 0.34 ENST00000234798.4
tryptase gamma 1
chr15_+_76336755 0.34 ENST00000290759.9
ISL LIM homeobox 2
chr15_-_77632869 0.34 ENST00000355300.7
leucine rich repeat and Ig domain containing 1
chr1_+_209938169 0.34 ENST00000367019.5
ENST00000537238.5
ENST00000637265.1
synaptotagmin 14
chr17_-_41047267 0.34 ENST00000542137.1
ENST00000391419.3
keratin associated protein 2-1
chr17_+_43847142 0.33 ENST00000377203.8
ENST00000539718.5
ENST00000588884.1
ENST00000293396.12
ENST00000586233.5
CD300 molecule like family member g
chr1_+_209938207 0.33 ENST00000472886.5
synaptotagmin 14
chr8_+_72537219 0.33 ENST00000523207.2
potassium voltage-gated channel subfamily B member 2
chr11_+_2301987 0.33 ENST00000612299.4
ENST00000182290.9
tetraspanin 32
chr6_+_37353972 0.33 ENST00000373479.9
ring finger protein 8
chrX_-_152138547 0.33 ENST00000577437.1
ENST00000427322.6
ENST00000370323.9
ENST00000244096.7
MAGEA10-MAGEA5 readthrough
MAGE family member A10

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 19.8 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.9 3.6 GO:0021649 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.9 3.4 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.6 4.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.6 7.4 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.5 1.6 GO:0090076 regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443) relaxation of skeletal muscle(GO:0090076)
0.5 10.0 GO:0016540 protein autoprocessing(GO:0016540)
0.5 1.5 GO:0015917 aminophospholipid transport(GO:0015917)
0.5 5.9 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.4 1.3 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.4 2.7 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.4 3.8 GO:0071492 cellular response to UV-A(GO:0071492)
0.3 1.4 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.3 1.7 GO:0006177 GMP biosynthetic process(GO:0006177)
0.3 1.3 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.3 5.9 GO:0006183 GTP biosynthetic process(GO:0006183)
0.3 0.9 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.3 0.9 GO:0071988 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.3 1.5 GO:0042374 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.2 0.7 GO:1902869 regulation of amacrine cell differentiation(GO:1902869)
0.2 2.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.2 1.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.2 1.0 GO:2000910 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.2 4.2 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.2 1.6 GO:0050893 sensory processing(GO:0050893)
0.2 3.2 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.2 0.8 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.2 5.5 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.2 0.8 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626) response to odorant(GO:1990834)
0.2 0.6 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.2 1.1 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.2 2.7 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.1 0.7 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.7 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.9 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.6 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 0.4 GO:0060032 notochord regression(GO:0060032)
0.1 0.6 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 1.0 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.1 0.9 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.3 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 0.6 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.1 1.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.5 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 1.0 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 1.0 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.1 0.4 GO:0031049 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.1 1.2 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.1 0.7 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 1.7 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.8 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.5 GO:0045759 negative regulation of action potential(GO:0045759)
0.1 0.6 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 0.4 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.1 0.5 GO:0051697 protein delipidation(GO:0051697)
0.1 0.8 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 1.1 GO:0043320 natural killer cell degranulation(GO:0043320)
0.1 1.1 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 0.4 GO:0002775 antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778)
0.1 0.4 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.1 0.2 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 0.1 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.1 1.9 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 1.4 GO:0003334 keratinocyte development(GO:0003334)
0.1 6.5 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 0.6 GO:1903546 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to photoreceptor outer segment(GO:1903546)
0.1 0.9 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.2 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.1 0.2 GO:0006059 hexitol metabolic process(GO:0006059)
0.1 0.5 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 0.4 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.6 GO:0070970 interleukin-2 secretion(GO:0070970)
0.0 1.4 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.8 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.8 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.3 GO:0032439 endosome localization(GO:0032439)
0.0 0.8 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 1.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.6 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 1.1 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.9 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.4 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.8 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.2 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:0046968 peptide antigen transport(GO:0046968)
0.0 1.3 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.6 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.3 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.7 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.1 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.0 0.6 GO:0035855 megakaryocyte development(GO:0035855)
0.0 1.0 GO:0032402 melanosome transport(GO:0032402)
0.0 0.6 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 2.7 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.2 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0 4.5 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.1 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147) negative regulation of glial cell migration(GO:1903976)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.3 GO:0042756 drinking behavior(GO:0042756)
0.0 0.2 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.4 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.9 GO:0050718 positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0 0.3 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 1.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.8 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.6 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.1 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.7 GO:0030252 growth hormone secretion(GO:0030252)
0.0 3.8 GO:0031424 keratinization(GO:0031424)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 1.6 GO:0090307 mitotic spindle assembly(GO:0090307)
0.0 1.5 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.4 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.6 GO:0046039 GTP metabolic process(GO:0046039)
0.0 0.8 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.3 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.0 0.0 GO:0046080 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.0 0.1 GO:1902022 lysine transport(GO:0015819) L-lysine transport(GO:1902022) L-lysine transmembrane transport(GO:1903401)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.6 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.9 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.5 GO:0021983 pituitary gland development(GO:0021983)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.1 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.1 GO:0000338 protein deneddylation(GO:0000338)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 19.8 GO:0097209 epidermal lamellar body(GO:0097209)
0.8 6.5 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.5 2.2 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.4 2.1 GO:0031523 Myb complex(GO:0031523)
0.4 3.6 GO:0097443 sorting endosome(GO:0097443)
0.3 0.9 GO:0055028 cortical microtubule(GO:0055028)
0.2 0.4 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 7.2 GO:0030673 axolemma(GO:0030673)
0.1 0.8 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 1.7 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 2.8 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 1.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.1 GO:0051286 cell tip(GO:0051286)
0.1 0.8 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 1.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 1.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 0.6 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 1.0 GO:0005869 dynactin complex(GO:0005869)
0.1 2.4 GO:0042629 mast cell granule(GO:0042629)
0.1 2.6 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.0 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.1 0.6 GO:0070852 cell body fiber(GO:0070852)
0.1 4.5 GO:0045095 keratin filament(GO:0045095)
0.1 1.0 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 5.5 GO:0045178 basal part of cell(GO:0045178)
0.1 1.2 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 1.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 5.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 4.2 GO:0005882 intermediate filament(GO:0005882)
0.0 0.4 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 1.9 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.6 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.9 GO:0042588 zymogen granule(GO:0042588)
0.0 1.0 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.3 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.4 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 1.3 GO:0032420 stereocilium(GO:0032420)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 2.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 3.6 GO:0005903 brush border(GO:0005903)
0.0 0.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 4.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 2.1 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.7 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.4 GO:0097546 ciliary base(GO:0097546)
0.0 0.7 GO:0002102 podosome(GO:0002102)
0.0 0.8 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.2 GO:0000800 lateral element(GO:0000800)
0.0 0.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0030305 heparanase activity(GO:0030305)
0.7 2.2 GO:0030290 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.6 3.4 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.5 3.2 GO:1990254 keratin filament binding(GO:1990254)
0.5 1.5 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.5 1.4 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.4 3.6 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.4 1.7 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.4 7.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.4 1.5 GO:0030226 apolipoprotein receptor activity(GO:0030226)
0.4 5.9 GO:1901612 cardiolipin binding(GO:1901612)
0.3 1.4 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.3 5.9 GO:0008179 adenylate cyclase binding(GO:0008179)
0.3 0.9 GO:0032090 Pyrin domain binding(GO:0032090)
0.3 5.5 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.2 1.8 GO:0071532 ankyrin repeat binding(GO:0071532)
0.2 0.8 GO:0005042 netrin receptor activity(GO:0005042)
0.2 1.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.2 2.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.2 0.9 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.2 0.8 GO:0005502 11-cis retinal binding(GO:0005502)
0.2 0.6 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.2 0.9 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.9 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 0.7 GO:0016936 galactoside binding(GO:0016936)
0.1 0.6 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.5 GO:0005163 nerve growth factor receptor binding(GO:0005163)
0.1 0.9 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.4 GO:0070984 SET domain binding(GO:0070984)
0.1 0.5 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 1.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.8 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.4 GO:0035501 MH1 domain binding(GO:0035501)
0.1 1.1 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.3 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.1 5.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 25.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.9 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 1.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.9 GO:0046625 sphingolipid binding(GO:0046625)
0.1 0.6 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 1.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.5 GO:0071253 connexin binding(GO:0071253)
0.0 0.2 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.2 GO:0004335 galactokinase activity(GO:0004335)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 1.0 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.7 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 1.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.6 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.4 GO:0032027 myosin light chain binding(GO:0032027)
0.0 4.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.8 GO:0048156 tau protein binding(GO:0048156)
0.0 1.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.8 GO:0017166 vinculin binding(GO:0017166)
0.0 0.5 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 1.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.7 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.9 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0089720 caspase binding(GO:0089720)
0.0 0.0 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.0 1.7 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.1 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.9 GO:0019003 GDP binding(GO:0019003)
0.0 0.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.7 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 1.6 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 11.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 3.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.2 10.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 4.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 3.9 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 2.4 PID S1P S1P3 PATHWAY S1P3 pathway
0.1 1.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 3.2 PID AURORA B PATHWAY Aurora B signaling
0.0 2.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 2.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 2.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 2.4 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.7 PID ATM PATHWAY ATM pathway
0.0 0.8 PID CDC42 PATHWAY CDC42 signaling events
0.0 1.5 PID FGF PATHWAY FGF signaling pathway
0.0 0.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.8 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.8 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.5 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.2 PID E2F PATHWAY E2F transcription factor network
0.0 0.6 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 11.6 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.2 3.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 5.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 2.7 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 0.9 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.1 2.5 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.1 0.4 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 1.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 2.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 0.9 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.0 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 1.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.9 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 3.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.6 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.9 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 2.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 1.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 1.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.9 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 3.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix