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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for RUNX3_BCL11A

Z-value: 0.75

Motif logo

Transcription factors associated with RUNX3_BCL11A

Gene Symbol Gene ID Gene Info
ENSG00000020633.19 RUNX3
ENSG00000119866.22 BCL11A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BCL11Ahg38_v1_chr2_-_60553409_605534610.641.3e-04Click!
RUNX3hg38_v1_chr1_-_24930263_249302820.412.5e-02Click!

Activity profile of RUNX3_BCL11A motif

Sorted Z-values of RUNX3_BCL11A motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RUNX3_BCL11A

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_+_17228215 2.02 ENST00000544301.7
vimentin
chr22_+_31082860 1.82 ENST00000619644.4
smoothelin
chr11_-_58578096 1.42 ENST00000528954.5
ENST00000528489.1
leupaxin
chr3_-_151203201 1.25 ENST00000480322.1
ENST00000309180.6
G protein-coupled receptor 171
chr3_-_33645253 1.19 ENST00000333778.10
cytoplasmic linker associated protein 2
chr11_-_102955705 1.11 ENST00000615555.4
ENST00000340273.4
ENST00000260302.8
matrix metallopeptidase 13
chr5_-_39270623 1.06 ENST00000512138.1
ENST00000646045.2
FYN binding protein 1
chr10_+_25174969 1.05 ENST00000376351.4
G protein-coupled receptor 158
chr4_+_87975667 1.04 ENST00000237623.11
ENST00000682655.1
ENST00000508233.6
ENST00000360804.4
ENST00000395080.8
secreted phosphoprotein 1
chr10_+_25174796 1.04 ENST00000650135.1
G protein-coupled receptor 158
chr3_+_100609594 1.00 ENST00000273352.8
adhesion G protein-coupled receptor G7
chr4_+_87975829 0.97 ENST00000614857.5
secreted phosphoprotein 1
chr19_-_43780957 0.87 ENST00000648319.1
potassium calcium-activated channel subfamily N member 4
chr13_-_61427849 0.83 ENST00000409186.1
ENST00000472649.2
novel protein
long intergenic non-protein coding RNA 2339
chr9_-_120876356 0.83 ENST00000456291.1
PHD finger protein 19
chr13_-_102401599 0.80 ENST00000376131.8
fibroblast growth factor 14
chr12_+_14973020 0.79 ENST00000266395.3
phosphodiesterase 6H
chrX_-_107717054 0.77 ENST00000503515.1
ENST00000372397.6
TSC22 domain family member 3
chr9_-_120877026 0.74 ENST00000436309.5
PHD finger protein 19
chr12_+_48978313 0.71 ENST00000293549.4
Wnt family member 1
chr12_+_48978453 0.69 ENST00000613114.4
Wnt family member 1
chr10_-_13234329 0.69 ENST00000463405.2
upper zone of growth plate and cartilage matrix associated
chr10_-_13234368 0.68 ENST00000378681.8
upper zone of growth plate and cartilage matrix associated
chr12_-_51324091 0.67 ENST00000604560.6
bridging integrator 2
chr1_+_44739825 0.66 ENST00000372224.9
kinesin family member 2C
chr8_-_71361860 0.65 ENST00000303824.11
ENST00000645451.1
EYA transcriptional coactivator and phosphatase 1
chr8_-_71362054 0.65 ENST00000340726.8
EYA transcriptional coactivator and phosphatase 1
chr12_-_51324138 0.63 ENST00000452142.7
bridging integrator 2
chr8_+_22042790 0.63 ENST00000359441.4
fibroblast growth factor 17
chr1_-_93681829 0.63 ENST00000260502.11
BCAR3 adaptor protein, NSP family member
chr12_-_51324164 0.62 ENST00000615107.6
bridging integrator 2
chr7_+_30852273 0.62 ENST00000509504.2
novel protein, MINDY4 and AQP1 readthrough
chr2_-_157444044 0.61 ENST00000264192.8
cytohesin 1 interacting protein
chr10_+_110644306 0.59 ENST00000369519.4
RNA binding motif protein 20
chr3_-_33645433 0.58 ENST00000635664.1
ENST00000485378.6
ENST00000313350.10
ENST00000487200.5
cytoplasmic linker associated protein 2
chr5_-_39202991 0.57 ENST00000515010.5
FYN binding protein 1
chr2_-_55419565 0.56 ENST00000647341.1
ENST00000647401.1
ENST00000336838.10
ENST00000621814.4
ENST00000644033.1
ENST00000645477.1
ENST00000647517.1
coiled-coil domain containing 88A
chr4_-_57110373 0.54 ENST00000295666.6
ENST00000514062.2
insulin like growth factor binding protein 7
chr1_-_149917826 0.53 ENST00000369145.1
ENST00000369146.8
synaptic vesicle glycoprotein 2A
chr2_-_55419821 0.52 ENST00000644630.1
ENST00000471947.2
ENST00000436346.7
ENST00000642200.1
ENST00000413716.7
ENST00000263630.13
ENST00000645072.1
coiled-coil domain containing 88A
chr21_+_30396030 0.51 ENST00000355459.4
keratin associated protein 13-1
chr7_+_120988683 0.51 ENST00000340646.9
ENST00000310396.10
cadherin like and PC-esterase domain containing 1
chr11_-_35265696 0.47 ENST00000464522.2
solute carrier family 1 member 2
chr1_-_24964984 0.47 ENST00000338888.3
ENST00000399916.5
RUNX family transcription factor 3
chr1_+_152514474 0.45 ENST00000368790.4
cysteine rich C-terminal 1
chr2_-_55296361 0.45 ENST00000647547.1
coiled-coil domain containing 88A
chr2_-_50347710 0.43 ENST00000342183.9
ENST00000401710.5
neurexin 1
chr2_-_191150971 0.43 ENST00000409995.5
ENST00000392320.7
signal transducer and activator of transcription 4
chr1_+_66534082 0.42 ENST00000683257.1
ENST00000684083.1
ENST00000682938.1
ENST00000683581.1
ENST00000682293.1
SH3GL interacting endocytic adaptor 1
chr19_-_43781249 0.42 ENST00000615047.4
potassium calcium-activated channel subfamily N member 4
chrX_-_136780925 0.41 ENST00000250617.7
Rac/Cdc42 guanine nucleotide exchange factor 6
chr1_+_66534107 0.41 ENST00000371037.9
ENST00000684651.1
SH3GL interacting endocytic adaptor 1
chr11_-_66958366 0.40 ENST00000651036.1
ENST00000652125.1
ENST00000531614.6
ENST00000524491.6
ENST00000529047.6
ENST00000393960.7
ENST00000393958.7
ENST00000528403.6
ENST00000651854.1
pyruvate carboxylase
chr1_+_66534171 0.40 ENST00000682762.1
ENST00000424320.6
SH3GL interacting endocytic adaptor 1
chr4_-_149815826 0.40 ENST00000636793.2
ENST00000636414.1
IQ motif containing M
chr8_+_22042382 0.40 ENST00000518533.5
fibroblast growth factor 17
chr9_-_92404559 0.39 ENST00000262551.8
ENST00000375561.10
osteoglycin
chr11_-_31803620 0.39 ENST00000639006.1
paired box 6
chr1_+_209686173 0.39 ENST00000615289.4
ENST00000367028.6
ENST00000261465.5
hydroxysteroid 11-beta dehydrogenase 1
chr2_-_2324323 0.38 ENST00000648339.1
ENST00000647694.1
myelin transcription factor 1 like
chr6_-_114343012 0.38 ENST00000312719.10
heparan sulfate-glucosamine 3-sulfotransferase 5
chr5_+_35856883 0.37 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
interleukin 7 receptor
chr7_+_18495723 0.37 ENST00000681950.1
ENST00000622668.4
ENST00000405010.7
ENST00000406451.8
ENST00000441542.7
ENST00000428307.6
ENST00000681273.1
histone deacetylase 9
chr11_-_31803663 0.36 ENST00000638802.1
ENST00000638878.1
paired box 6
chr4_+_70226116 0.36 ENST00000317987.6
follicular dendritic cell secreted protein
chr16_+_85908988 0.35 ENST00000566369.1
interferon regulatory factor 8
chr2_-_2324642 0.35 ENST00000650485.1
ENST00000649207.1
myelin transcription factor 1 like
chr13_-_46182136 0.34 ENST00000323076.7
lymphocyte cytosolic protein 1
chr2_+_168802563 0.34 ENST00000445023.6
nitric oxide synthase trafficking
chrX_-_71618455 0.34 ENST00000373691.4
ENST00000373693.4
C-X-C motif chemokine receptor 3
chr11_-_19240936 0.34 ENST00000250024.9
E2F transcription factor 8
chr12_-_70637405 0.34 ENST00000548122.2
ENST00000551525.5
ENST00000550358.5
ENST00000334414.11
protein tyrosine phosphatase receptor type B
chr1_-_168543990 0.33 ENST00000367819.3
X-C motif chemokine ligand 2
chr2_+_168802610 0.33 ENST00000397206.6
ENST00000317647.12
ENST00000397209.6
nitric oxide synthase trafficking
chr9_-_122213903 0.33 ENST00000464484.3
LIM homeobox 6
chr5_+_136160986 0.33 ENST00000507637.1
SMAD family member 5
chr1_+_109910485 0.33 ENST00000525659.5
colony stimulating factor 1
chr2_+_33134579 0.32 ENST00000418533.6
latent transforming growth factor beta binding protein 1
chr12_-_52618559 0.32 ENST00000305748.7
keratin 73
chr6_+_73695779 0.32 ENST00000422508.6
ENST00000437994.6
CD109 molecule
chr8_-_133060347 0.32 ENST00000427060.6
Src like adaptor
chr11_+_124865425 0.32 ENST00000397801.6
roundabout guidance receptor 3
chr6_+_30061231 0.32 ENST00000376782.6
ENST00000359374.8
ENST00000376785.2
ENST00000332435.10
RNA polymerase I subunit H
chr5_-_139482285 0.32 ENST00000652110.1
stimulator of interferon response cGAMP interactor 1
chrX_-_15854791 0.32 ENST00000545766.7
ENST00000380291.5
ENST00000672987.1
ENST00000329235.6
adaptor related protein complex 1 subunit sigma 2
chr9_-_122213874 0.31 ENST00000482062.1
LIM homeobox 6
chr19_-_48993300 0.31 ENST00000323798.8
ENST00000263276.6
glycogen synthase 1
chr1_+_109910986 0.31 ENST00000369801.1
colony stimulating factor 1
chr14_+_85530127 0.31 ENST00000330753.6
fibronectin leucine rich transmembrane protein 2
chr4_-_10684749 0.31 ENST00000226951.11
cytokine dependent hematopoietic cell linker
chr20_+_37777262 0.31 ENST00000373469.1
catenin beta like 1
chr3_-_71130557 0.31 ENST00000497355.7
forkhead box P1
chr3_-_71130963 0.30 ENST00000649695.2
forkhead box P1
chr17_-_43758780 0.30 ENST00000301691.3
sclerostin
chr6_-_42451261 0.30 ENST00000372917.8
ENST00000340840.6
ENST00000354325.2
transcriptional regulating factor 1
chr13_-_28100556 0.30 ENST00000241453.12
fms related receptor tyrosine kinase 3
chr14_-_70188967 0.30 ENST00000381269.6
ENST00000357887.7
solute carrier family 8 member A3
chr19_+_41376692 0.30 ENST00000447302.6
ENST00000544232.5
ENST00000542945.5
ENST00000540732.3
transmembrane protein 91
novel protein
chr14_-_70188937 0.29 ENST00000356921.7
solute carrier family 8 member A3
chr3_+_141386393 0.29 ENST00000503809.5
zinc finger and BTB domain containing 38
chr6_+_45328203 0.28 ENST00000371432.7
ENST00000647337.2
ENST00000371438.5
RUNX family transcription factor 2
chr2_+_181985846 0.28 ENST00000682840.1
ENST00000409137.7
ENST00000280295.7
protein phosphatase 1 regulatory inhibitor subunit 1C
chr3_+_96814552 0.28 ENST00000470610.6
ENST00000389672.9
EPH receptor A6
chr5_+_172959511 0.28 ENST00000519522.1
ribosomal protein L26 like 1
chr10_+_5524953 0.27 ENST00000315238.3
calmodulin like 3
chr14_+_21868822 0.27 ENST00000390436.2
T cell receptor alpha variable 13-1
chr5_-_139482341 0.27 ENST00000651699.1
stimulator of interferon response cGAMP interactor 1
chr12_+_75481204 0.27 ENST00000550491.1
GLI pathogenesis related 1
chr2_+_202073282 0.27 ENST00000459709.5
KIAA2012
chrX_+_68829009 0.27 ENST00000204961.5
ephrin B1
chr7_-_148883474 0.26 ENST00000476773.5
enhancer of zeste 2 polycomb repressive complex 2 subunit
chrX_+_37780049 0.26 ENST00000378588.5
cytochrome b-245 beta chain
chrX_-_15854743 0.26 ENST00000450644.2
adaptor related protein complex 1 subunit sigma 2
chr12_-_10390023 0.26 ENST00000240618.11
killer cell lectin like receptor K1
chr1_-_173205543 0.26 ENST00000367718.5
TNF superfamily member 4
chr1_+_6555301 0.25 ENST00000333172.11
ENST00000351136.7
taste 1 receptor member 1
chr1_-_182672232 0.25 ENST00000508450.5
regulator of G protein signaling 8
chr3_+_155083889 0.25 ENST00000680282.1
membrane metalloendopeptidase
chr12_-_16606795 0.25 ENST00000447609.5
LIM domain only 3
chr4_-_80072993 0.25 ENST00000681115.1
ANTXR cell adhesion molecule 2
chr1_-_179143044 0.25 ENST00000504405.5
ENST00000512653.5
ENST00000344730.7
ABL proto-oncogene 2, non-receptor tyrosine kinase
chr3_-_190122317 0.24 ENST00000427335.6
prolyl 3-hydroxylase 2
chr11_-_2301859 0.24 ENST00000456145.2
ENST00000381153.8
chromosome 11 open reading frame 21
chr5_-_139482173 0.24 ENST00000652271.1
stimulator of interferon response cGAMP interactor 1
chr17_-_49210567 0.24 ENST00000507680.6
G protein subunit gamma transducin 2
chr12_+_79045625 0.24 ENST00000552744.5
synaptotagmin 1
chr19_-_48321857 0.24 ENST00000474199.6
outer dynein arm docking complex subunit 1
chr3_+_155083523 0.24 ENST00000680057.1
membrane metalloendopeptidase
chr17_-_2266131 0.24 ENST00000570606.5
ENST00000354901.8
SMG6 nonsense mediated mRNA decay factor
chr22_-_23141980 0.24 ENST00000216036.9
radial spoke head 14 homolog
chr20_+_56412112 0.23 ENST00000360314.7
Cas scaffold protein family member 4
chr14_-_34714549 0.23 ENST00000555765.5
ENST00000672517.1
cofilin 2
chr19_-_48321948 0.23 ENST00000674294.1
outer dynein arm docking complex subunit 1
chr1_-_157552470 0.22 ENST00000361835.8
Fc receptor like 5
chr9_+_116153783 0.22 ENST00000328252.4
pappalysin 1
chr14_-_34714579 0.22 ENST00000298159.11
cofilin 2
chr19_+_7348930 0.22 ENST00000668164.2
Rho/Rac guanine nucleotide exchange factor 18
chr4_-_151226427 0.22 ENST00000304527.8
ENST00000409598.8
SH3 domain containing 19
chr14_+_85530163 0.22 ENST00000554746.1
fibronectin leucine rich transmembrane protein 2
chr17_-_58417547 0.22 ENST00000577716.5
ring finger protein 43
chr20_+_56412393 0.22 ENST00000679529.1
Cas scaffold protein family member 4
chr2_+_37344594 0.21 ENST00000404976.5
ENST00000338415.8
glutaminyl-peptide cyclotransferase
chr17_-_58417521 0.21 ENST00000584437.5
ENST00000407977.7
ring finger protein 43
chr2_+_33134620 0.21 ENST00000402934.5
ENST00000404525.5
ENST00000407925.5
latent transforming growth factor beta binding protein 1
chr2_-_49154433 0.21 ENST00000454032.5
ENST00000304421.8
follicle stimulating hormone receptor
chr11_-_62689523 0.21 ENST00000317449.5
LRRN4 C-terminal like
chr6_-_52244500 0.21 ENST00000336123.5
interleukin 17F
chr2_-_49154507 0.21 ENST00000406846.7
follicle stimulating hormone receptor
chr1_-_24143112 0.21 ENST00000270800.2
interleukin 22 receptor subunit alpha 1
chr10_+_99659430 0.20 ENST00000370489.5
ectonucleoside triphosphate diphosphohydrolase 7
chr6_-_29045175 0.20 ENST00000377175.2
olfactory receptor family 2 subfamily W member 1
chr2_+_74529923 0.20 ENST00000258080.8
ENST00000352222.7
HtrA serine peptidase 2
chr15_+_43185382 0.20 ENST00000300213.9
cyclin D1 binding protein 1
chr17_-_10114546 0.20 ENST00000323816.8
growth arrest specific 7
chr3_-_71130892 0.20 ENST00000491238.7
ENST00000674446.1
forkhead box P1
chr1_+_236394268 0.19 ENST00000334232.9
EDAR associated death domain
chr20_+_56412249 0.19 ENST00000679887.1
ENST00000434344.2
Cas scaffold protein family member 4
chr14_-_59484317 0.19 ENST00000247194.9
trans-L-3-hydroxyproline dehydratase
chr22_+_39901075 0.19 ENST00000344138.9
GRB2 related adaptor protein 2
chr3_+_133124807 0.19 ENST00000508711.5
transmembrane protein 108
chr11_+_124611420 0.19 ENST00000284288.3
pannexin 3
chr12_-_68159732 0.19 ENST00000229135.4
interferon gamma
chr16_+_87602478 0.19 ENST00000284262.3
junctophilin 3
chr9_-_34048868 0.19 ENST00000379239.9
ENST00000684158.1
ENST00000379238.7
ENST00000360802.6
ubiquitin associated protein 2
chrX_+_79144664 0.18 ENST00000645147.2
G protein-coupled receptor 174
chr7_-_29195186 0.18 ENST00000449801.5
ENST00000409850.5
carboxypeptidase vitellogenic like
chr19_-_50365625 0.18 ENST00000598915.5
ENST00000253719.7
napsin A aspartic peptidase
chr7_-_87475647 0.18 ENST00000649586.2
ENST00000265723.8
ATP binding cassette subfamily B member 4
chr11_+_77179750 0.18 ENST00000458169.2
myosin VIIA
chr20_+_31440626 0.18 ENST00000376309.4
defensin beta 123
chr19_+_40751179 0.18 ENST00000243563.8
ENST00000601393.1
small nuclear ribonucleoprotein polypeptide A
chr5_+_55102635 0.17 ENST00000274306.7
granzyme A
chr14_+_64214136 0.17 ENST00000557084.1
ENST00000458046.6
spectrin repeat containing nuclear envelope protein 2
chr6_+_25279061 0.17 ENST00000461945.1
capping protein regulator and myosin 1 linker 1
chr2_+_183078736 0.17 ENST00000354221.5
dual specificity phosphatase 19
chr12_-_54300974 0.17 ENST00000435572.7
ENST00000553070.5
nuclear factor, erythroid 2
chr6_+_31575557 0.17 ENST00000449264.3
tumor necrosis factor
chr16_+_31355165 0.17 ENST00000562918.5
ENST00000268296.9
integrin subunit alpha X
chr3_-_185821092 0.17 ENST00000421047.3
insulin like growth factor 2 mRNA binding protein 2
chr15_+_49423233 0.16 ENST00000560270.1
ENST00000267843.9
ENST00000560979.1
fibroblast growth factor 7
chr7_+_142598016 0.16 ENST00000620773.1
T cell receptor beta variable 16
chr2_+_202073249 0.16 ENST00000498697.3
KIAA2012
chr1_+_109910892 0.16 ENST00000369802.7
ENST00000420111.6
colony stimulating factor 1
chr6_-_34556319 0.16 ENST00000374037.8
ENST00000544425.2
SAM pointed domain containing ETS transcription factor
chr19_-_14674886 0.16 ENST00000344373.8
ENST00000595472.1
adhesion G protein-coupled receptor E3
chr5_-_128339191 0.16 ENST00000507835.5
fibrillin 2
chrX_-_77969638 0.15 ENST00000458128.3
phosphoglycerate mutase family member 4
chr17_+_8310814 0.15 ENST00000579439.5
ENST00000421050.2
Rho guanine nucleotide exchange factor 15
chr1_+_39081316 0.15 ENST00000484793.5
microtubule actin crosslinking factor 1
chr2_+_102418642 0.15 ENST00000264260.6
interleukin 18 receptor accessory protein
chr19_+_39997031 0.15 ENST00000599504.5
ENST00000596894.5
ENST00000601138.5
ENST00000347077.9
ENST00000600094.5
zinc finger protein 546
chr6_-_107459504 0.15 ENST00000369037.9
ENST00000369031.4
decaprenyl diphosphate synthase subunit 2
chr19_-_14674829 0.15 ENST00000443157.6
ENST00000253673.6
adhesion G protein-coupled receptor E3
chr11_+_60971777 0.15 ENST00000542157.5
ENST00000433107.6
ENST00000352009.9
ENST00000452451.6
CD6 molecule
chr19_-_409134 0.15 ENST00000332235.8
C2 calcium dependent domain containing 4C
chr6_-_118710065 0.15 ENST00000392500.7
ENST00000368488.9
ENST00000434604.5
centrosomal protein 85 like
chr17_+_49210699 0.14 ENST00000225941.6
ABI family member 3
chr17_-_41811930 0.14 ENST00000393928.6
prolyl 3-hydroxylase family member 4 (inactive)
chr11_-_31804067 0.14 ENST00000639548.1
ENST00000640125.1
ENST00000481563.6
ENST00000639079.1
ENST00000638762.1
ENST00000638346.1
paired box 6
chr19_-_42132465 0.14 ENST00000529067.5
ENST00000529952.5
ENST00000342301.8
ENST00000389341.9
POU class 2 homeobox 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.5 1.4 GO:0061184 positive regulation of dermatome development(GO:0061184)
0.3 1.5 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.2 0.8 GO:0060611 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.2 1.4 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.2 1.6 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 1.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.4 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.1 2.0 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.1 0.4 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 0.4 GO:2000537 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.1 1.8 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.4 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.1 0.3 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 0.4 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.3 GO:2001025 response to cyclosporin A(GO:1905237) positive regulation of response to drug(GO:2001025)
0.1 0.4 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 1.4 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.3 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.1 0.3 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 0.7 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.3 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.1 0.8 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 1.2 GO:0046541 saliva secretion(GO:0046541)
0.1 0.4 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.3 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.1 0.3 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.1 0.7 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.6 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.5 GO:0051414 response to cortisol(GO:0051414)
0.1 1.9 GO:0097320 membrane tubulation(GO:0097320)
0.1 0.3 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.6 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 0.9 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.2 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.1 1.1 GO:0003417 growth plate cartilage development(GO:0003417)
0.1 0.2 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.1 0.6 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0 0.5 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.2 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.8 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.6 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 0.6 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.4 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.1 GO:0071104 response to interleukin-9(GO:0071104)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.1 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.3 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.2 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.2 GO:0060437 lung growth(GO:0060437)
0.0 0.3 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.3 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.1 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.0 0.3 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.2 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.7 GO:0097106 postsynaptic density organization(GO:0097106)
0.0 0.3 GO:0002318 myeloid progenitor cell differentiation(GO:0002318) common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.9 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.5 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:1990523 bone regeneration(GO:1990523)
0.0 0.5 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.3 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.5 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:0051695 actin filament uncapping(GO:0051695)
0.0 0.4 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456) positive regulation of sperm motility(GO:1902093)
0.0 0.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.3 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899)
0.0 1.5 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.1 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.8 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.1 GO:0032826 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.0 0.2 GO:0043129 surfactant homeostasis(GO:0043129)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 0.1 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.0 0.7 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.1 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.4 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.1 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.2 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071) negative regulation of nuclease activity(GO:0032074)
0.0 0.0 GO:0070676 intralumenal vesicle formation(GO:0070676) negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.2 GO:0034214 protein hexamerization(GO:0034214)
0.0 1.0 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.1 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.0 0.1 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.4 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 1.8 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.2 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 2.2 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 1.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.2 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.7 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.5 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.6 GO:0016235 aggresome(GO:0016235)
0.0 1.4 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.2 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.2 GO:0070449 elongin complex(GO:0070449)
0.0 0.3 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.7 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 1.8 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 2.3 GO:0005882 intermediate filament(GO:0005882)
0.0 1.6 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.0 GO:0097196 Shu complex(GO:0097196)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:1990254 keratin filament binding(GO:1990254)
0.3 1.0 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.4 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.1 1.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.4 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.8 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 1.4 GO:0016015 morphogen activity(GO:0016015)
0.1 0.5 GO:0050436 microfibril binding(GO:0050436)
0.1 0.3 GO:0016855 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.1 0.8 GO:0043426 MRF binding(GO:0043426)
0.1 2.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.4 GO:0042835 BRE binding(GO:0042835)
0.1 0.6 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 1.5 GO:0043422 protein kinase B binding(GO:0043422)
0.1 0.2 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.1 0.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.3 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.3 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.0 0.2 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.9 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.4 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.4 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.3 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.2 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.7 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.5 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 1.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.1 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.0 0.3 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.4 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 1.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.5 GO:0097109 acetylcholine receptor binding(GO:0033130) neuroligin family protein binding(GO:0097109)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 1.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 1.2 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237) glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.4 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.7 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 2.7 PID AURORA B PATHWAY Aurora B signaling
0.0 1.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.0 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.9 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.6 PID FGF PATHWAY FGF signaling pathway
0.0 0.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.4 PID GMCSF PATHWAY GMCSF-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.0 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.6 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.9 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.7 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.2 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 2.0 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 0.4 REACTOME STEROID HORMONES Genes involved in Steroid hormones