Project
Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
Navigation
Downloads
Results for RXRG
Z-value: 1.12
Motif logo
Transcription factors associated with RXRG
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
RXRG
|
ENSG00000143171.13 | RXRG |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| RXRG | hg38_v1_chr1_-_165445220_165445355, hg38_v1_chr1_-_165445088_165445140 | -0.27 | 1.5e-01 | Click! |
Activity profile of RXRG motif
Sorted Z-values of RXRG motif
Network of associatons between targets according to the STRING database.
First level regulatory network of RXRG
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 3.1 | GO:1903570 | regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572) |
| 0.9 | 3.5 | GO:0045659 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
| 0.6 | 8.5 | GO:0031642 | negative regulation of myelination(GO:0031642) |
| 0.5 | 1.1 | GO:0046379 | extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) |
| 0.5 | 1.5 | GO:0046005 | positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005) |
| 0.5 | 2.0 | GO:0042631 | cellular response to water deprivation(GO:0042631) |
| 0.5 | 1.4 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
| 0.5 | 1.9 | GO:1900535 | medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535) |
| 0.5 | 1.9 | GO:1900085 | negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609) |
| 0.5 | 2.3 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
| 0.5 | 1.4 | GO:0090076 | regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443) relaxation of skeletal muscle(GO:0090076) |
| 0.5 | 2.7 | GO:1900104 | hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) |
| 0.4 | 1.3 | GO:1905000 | regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000) |
| 0.4 | 2.6 | GO:0061143 | alveolar primary septum development(GO:0061143) |
| 0.4 | 1.2 | GO:0033082 | regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654) |
| 0.4 | 1.6 | GO:0061034 | olfactory bulb mitral cell layer development(GO:0061034) |
| 0.4 | 1.1 | GO:0042938 | dipeptide transport(GO:0042938) |
| 0.4 | 4.4 | GO:0098734 | macromolecule depalmitoylation(GO:0098734) |
| 0.4 | 1.1 | GO:1901073 | N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073) |
| 0.3 | 3.1 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) |
| 0.3 | 1.3 | GO:0070295 | renal water absorption(GO:0070295) |
| 0.3 | 1.3 | GO:0006175 | adenosine salvage(GO:0006169) dATP biosynthetic process(GO:0006175) |
| 0.3 | 1.3 | GO:1904117 | response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117) |
| 0.3 | 3.3 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
| 0.3 | 2.0 | GO:0071105 | response to interleukin-11(GO:0071105) |
| 0.3 | 1.0 | GO:1904717 | excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719) |
| 0.3 | 1.5 | GO:0046167 | glycerol-3-phosphate biosynthetic process(GO:0046167) |
| 0.3 | 1.1 | GO:2000371 | regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373) |
| 0.3 | 1.9 | GO:1904100 | regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100) |
| 0.3 | 0.8 | GO:0002378 | immunoglobulin biosynthetic process(GO:0002378) |
| 0.3 | 0.8 | GO:1900195 | positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777) |
| 0.3 | 1.3 | GO:0042853 | L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853) |
| 0.3 | 0.5 | GO:0075509 | receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509) |
| 0.3 | 1.3 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
| 0.2 | 1.0 | GO:0060084 | synaptic transmission involved in micturition(GO:0060084) |
| 0.2 | 1.0 | GO:0035627 | ceramide transport(GO:0035627) |
| 0.2 | 2.2 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
| 0.2 | 1.2 | GO:0042360 | vitamin E metabolic process(GO:0042360) |
| 0.2 | 1.2 | GO:1904073 | regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075) |
| 0.2 | 1.4 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.2 | 0.9 | GO:2000687 | negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687) |
| 0.2 | 2.3 | GO:0098795 | mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795) |
| 0.2 | 1.7 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.2 | 1.3 | GO:0060631 | regulation of meiosis I(GO:0060631) |
| 0.2 | 0.8 | GO:1903755 | regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755) |
| 0.2 | 0.8 | GO:0000432 | regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) |
| 0.2 | 1.6 | GO:0035879 | plasma membrane lactate transport(GO:0035879) |
| 0.2 | 0.8 | GO:0030047 | actin modification(GO:0030047) |
| 0.2 | 0.6 | GO:1903028 | positive regulation of opsonization(GO:1903028) |
| 0.2 | 1.1 | GO:0061767 | negative regulation of lung blood pressure(GO:0061767) |
| 0.2 | 0.7 | GO:0032581 | ER-dependent peroxisome organization(GO:0032581) |
| 0.2 | 3.1 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.2 | 0.4 | GO:1990737 | response to manganese-induced endoplasmic reticulum stress(GO:1990737) |
| 0.2 | 1.1 | GO:0036324 | vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) |
| 0.2 | 1.1 | GO:0046836 | glycolipid transport(GO:0046836) |
| 0.2 | 1.6 | GO:0001661 | conditioned taste aversion(GO:0001661) |
| 0.2 | 0.5 | GO:0000494 | box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258) |
| 0.2 | 0.7 | GO:0000961 | negative regulation of mitochondrial RNA catabolic process(GO:0000961) |
| 0.2 | 0.8 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 0.2 | 1.6 | GO:0051549 | positive regulation of keratinocyte migration(GO:0051549) |
| 0.2 | 1.4 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.2 | 2.5 | GO:0044351 | macropinocytosis(GO:0044351) |
| 0.2 | 1.6 | GO:1902714 | negative regulation of interferon-gamma secretion(GO:1902714) |
| 0.2 | 0.6 | GO:1904924 | negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924) |
| 0.2 | 0.8 | GO:0071802 | negative regulation of podosome assembly(GO:0071802) |
| 0.2 | 0.9 | GO:0051594 | detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594) |
| 0.2 | 1.2 | GO:0008626 | granzyme-mediated apoptotic signaling pathway(GO:0008626) |
| 0.2 | 1.7 | GO:0010968 | regulation of microtubule nucleation(GO:0010968) |
| 0.2 | 0.8 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) |
| 0.2 | 0.5 | GO:0014740 | negative regulation of muscle hyperplasia(GO:0014740) |
| 0.2 | 1.4 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 0.1 | 0.4 | GO:1904395 | positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) |
| 0.1 | 1.3 | GO:0035897 | proteolysis in other organism(GO:0035897) |
| 0.1 | 2.3 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 0.1 | 2.4 | GO:0030949 | positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949) |
| 0.1 | 0.9 | GO:0001712 | ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712) |
| 0.1 | 0.9 | GO:1902962 | regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) |
| 0.1 | 0.4 | GO:0048213 | Golgi vesicle prefusion complex stabilization(GO:0048213) |
| 0.1 | 0.8 | GO:0021773 | striatal medium spiny neuron differentiation(GO:0021773) |
| 0.1 | 1.0 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
| 0.1 | 0.7 | GO:0006021 | inositol biosynthetic process(GO:0006021) |
| 0.1 | 0.8 | GO:0046874 | quinolinate metabolic process(GO:0046874) |
| 0.1 | 0.4 | GO:0007518 | myoblast fate determination(GO:0007518) |
| 0.1 | 0.8 | GO:1904526 | regulation of microtubule binding(GO:1904526) |
| 0.1 | 2.0 | GO:0045078 | positive regulation of interferon-gamma biosynthetic process(GO:0045078) |
| 0.1 | 1.4 | GO:0002934 | desmosome organization(GO:0002934) |
| 0.1 | 0.3 | GO:1901899 | positive regulation of relaxation of cardiac muscle(GO:1901899) |
| 0.1 | 1.5 | GO:0035092 | sperm chromatin condensation(GO:0035092) |
| 0.1 | 0.7 | GO:0061762 | CAMKK-AMPK signaling cascade(GO:0061762) |
| 0.1 | 1.2 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
| 0.1 | 1.0 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
| 0.1 | 0.5 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
| 0.1 | 2.6 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
| 0.1 | 1.9 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.1 | 2.7 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.1 | 0.4 | GO:0000023 | maltose metabolic process(GO:0000023) |
| 0.1 | 0.6 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
| 0.1 | 0.3 | GO:0048560 | establishment of anatomical structure orientation(GO:0048560) |
| 0.1 | 0.3 | GO:0098974 | postsynaptic actin cytoskeleton organization(GO:0098974) |
| 0.1 | 1.8 | GO:0032926 | negative regulation of activin receptor signaling pathway(GO:0032926) |
| 0.1 | 0.6 | GO:0051585 | negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470) |
| 0.1 | 0.6 | GO:0032468 | Golgi calcium ion homeostasis(GO:0032468) |
| 0.1 | 1.0 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
| 0.1 | 2.2 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.1 | 0.5 | GO:1901091 | regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094) |
| 0.1 | 1.6 | GO:0006450 | regulation of translational fidelity(GO:0006450) |
| 0.1 | 5.7 | GO:0071470 | cellular response to osmotic stress(GO:0071470) |
| 0.1 | 0.1 | GO:0014873 | response to muscle activity involved in regulation of muscle adaptation(GO:0014873) |
| 0.1 | 0.2 | GO:0003342 | proepicardium development(GO:0003342) septum transversum development(GO:0003343) |
| 0.1 | 1.4 | GO:0042407 | cristae formation(GO:0042407) |
| 0.1 | 1.6 | GO:2000394 | positive regulation of lamellipodium morphogenesis(GO:2000394) |
| 0.1 | 0.4 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 0.1 | 0.4 | GO:0051866 | general adaptation syndrome(GO:0051866) |
| 0.1 | 1.2 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 0.1 | 0.4 | GO:1904016 | response to Thyroglobulin triiodothyronine(GO:1904016) |
| 0.1 | 1.3 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.1 | 0.5 | GO:0035105 | sterol regulatory element binding protein import into nucleus(GO:0035105) |
| 0.1 | 0.6 | GO:0032417 | positive regulation of sodium:proton antiporter activity(GO:0032417) |
| 0.1 | 3.3 | GO:0014059 | dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) |
| 0.1 | 0.6 | GO:0010757 | negative regulation of plasminogen activation(GO:0010757) |
| 0.1 | 1.2 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
| 0.1 | 0.2 | GO:0007195 | adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195) |
| 0.1 | 0.8 | GO:0090261 | positive regulation of inclusion body assembly(GO:0090261) |
| 0.1 | 0.4 | GO:0061668 | mitochondrial ribosome assembly(GO:0061668) |
| 0.1 | 0.9 | GO:0034465 | response to carbon monoxide(GO:0034465) |
| 0.1 | 1.7 | GO:0070508 | sterol import(GO:0035376) cholesterol import(GO:0070508) |
| 0.1 | 0.4 | GO:0033058 | directional locomotion(GO:0033058) |
| 0.1 | 0.2 | GO:0001732 | formation of cytoplasmic translation initiation complex(GO:0001732) |
| 0.1 | 0.7 | GO:0006335 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.1 | 0.5 | GO:0006701 | progesterone biosynthetic process(GO:0006701) |
| 0.1 | 1.0 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
| 0.1 | 0.3 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 0.1 | 0.9 | GO:0046855 | phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) |
| 0.1 | 0.4 | GO:0061083 | regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) |
| 0.1 | 1.3 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.1 | 0.6 | GO:0048630 | skeletal muscle tissue growth(GO:0048630) |
| 0.1 | 1.8 | GO:0070208 | protein heterotrimerization(GO:0070208) |
| 0.1 | 0.2 | GO:0038195 | urokinase plasminogen activator signaling pathway(GO:0038195) |
| 0.1 | 0.6 | GO:0045905 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 0.1 | 0.5 | GO:1901029 | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029) |
| 0.1 | 1.9 | GO:0002230 | positive regulation of defense response to virus by host(GO:0002230) |
| 0.1 | 0.5 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.1 | 0.4 | GO:1900264 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 0.1 | 2.2 | GO:0007020 | microtubule nucleation(GO:0007020) |
| 0.1 | 0.3 | GO:0038060 | nitric oxide-cGMP-mediated signaling pathway(GO:0038060) |
| 0.1 | 0.3 | GO:2000325 | regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327) |
| 0.1 | 0.3 | GO:0060017 | parathyroid gland development(GO:0060017) |
| 0.1 | 1.1 | GO:0008212 | mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212) |
| 0.1 | 1.5 | GO:0040020 | regulation of meiotic nuclear division(GO:0040020) |
| 0.1 | 0.2 | GO:0016256 | N-glycan processing to lysosome(GO:0016256) |
| 0.1 | 0.7 | GO:0032790 | ribosome disassembly(GO:0032790) |
| 0.1 | 0.3 | GO:0090370 | negative regulation of cholesterol efflux(GO:0090370) |
| 0.1 | 0.2 | GO:0098971 | anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971) |
| 0.1 | 1.1 | GO:0007130 | synaptonemal complex assembly(GO:0007130) |
| 0.1 | 0.4 | GO:0010533 | regulation of activation of Janus kinase activity(GO:0010533) |
| 0.1 | 0.3 | GO:0071442 | positive regulation of histone H3-K14 acetylation(GO:0071442) |
| 0.1 | 0.4 | GO:0032218 | riboflavin transport(GO:0032218) |
| 0.1 | 0.5 | GO:0050747 | sphingomyelin biosynthetic process(GO:0006686) positive regulation of lipoprotein metabolic process(GO:0050747) |
| 0.1 | 0.5 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
| 0.1 | 0.4 | GO:0090235 | regulation of metaphase plate congression(GO:0090235) |
| 0.1 | 0.4 | GO:0015811 | L-cystine transport(GO:0015811) |
| 0.1 | 0.7 | GO:0006307 | DNA dealkylation involved in DNA repair(GO:0006307) |
| 0.1 | 0.5 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
| 0.1 | 0.4 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910) |
| 0.0 | 0.0 | GO:0051140 | regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142) |
| 0.0 | 1.4 | GO:1902259 | regulation of delayed rectifier potassium channel activity(GO:1902259) |
| 0.0 | 1.0 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.0 | 2.2 | GO:0007176 | regulation of epidermal growth factor-activated receptor activity(GO:0007176) |
| 0.0 | 1.6 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.0 | 4.1 | GO:0043525 | positive regulation of neuron apoptotic process(GO:0043525) |
| 0.0 | 0.4 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
| 0.0 | 0.4 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
| 0.0 | 1.4 | GO:0008053 | mitochondrial fusion(GO:0008053) |
| 0.0 | 0.7 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.0 | 1.7 | GO:0022030 | cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030) |
| 0.0 | 0.3 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
| 0.0 | 0.2 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
| 0.0 | 0.5 | GO:2000628 | regulation of miRNA metabolic process(GO:2000628) |
| 0.0 | 1.1 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.0 | 0.2 | GO:0015862 | uridine transport(GO:0015862) |
| 0.0 | 0.1 | GO:0032242 | regulation of nucleoside transport(GO:0032242) |
| 0.0 | 0.4 | GO:0055089 | fatty acid homeostasis(GO:0055089) |
| 0.0 | 0.3 | GO:1901314 | negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) |
| 0.0 | 1.7 | GO:0060325 | face morphogenesis(GO:0060325) |
| 0.0 | 0.6 | GO:0010459 | negative regulation of heart rate(GO:0010459) |
| 0.0 | 0.4 | GO:0034625 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.0 | 0.9 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 0.0 | 0.3 | GO:0007144 | female meiosis I(GO:0007144) |
| 0.0 | 0.3 | GO:0060770 | negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) |
| 0.0 | 0.1 | GO:0071529 | cementum mineralization(GO:0071529) |
| 0.0 | 0.2 | GO:2001295 | malonyl-CoA biosynthetic process(GO:2001295) |
| 0.0 | 0.3 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.0 | 0.6 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.0 | 0.4 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
| 0.0 | 0.4 | GO:1904263 | positive regulation of TORC1 signaling(GO:1904263) |
| 0.0 | 0.8 | GO:0071800 | podosome assembly(GO:0071800) |
| 0.0 | 1.2 | GO:0032402 | melanosome transport(GO:0032402) |
| 0.0 | 0.8 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.0 | 0.1 | GO:0002774 | Fc receptor mediated inhibitory signaling pathway(GO:0002774) |
| 0.0 | 1.0 | GO:1902751 | positive regulation of cell cycle G2/M phase transition(GO:1902751) |
| 0.0 | 0.3 | GO:0035524 | proline transmembrane transport(GO:0035524) |
| 0.0 | 0.3 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.0 | 0.6 | GO:1901750 | leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750) |
| 0.0 | 0.2 | GO:0032439 | endosome localization(GO:0032439) |
| 0.0 | 0.3 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
| 0.0 | 0.6 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 0.0 | 0.8 | GO:0043162 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162) |
| 0.0 | 0.5 | GO:0003322 | pancreatic A cell development(GO:0003322) |
| 0.0 | 2.4 | GO:0030834 | regulation of actin filament depolymerization(GO:0030834) |
| 0.0 | 0.3 | GO:0046958 | nonassociative learning(GO:0046958) |
| 0.0 | 0.1 | GO:0021526 | medial motor column neuron differentiation(GO:0021526) |
| 0.0 | 5.3 | GO:0031424 | keratinization(GO:0031424) |
| 0.0 | 0.7 | GO:0030728 | ovulation(GO:0030728) |
| 0.0 | 0.5 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
| 0.0 | 0.3 | GO:0033327 | Leydig cell differentiation(GO:0033327) |
| 0.0 | 1.0 | GO:0022400 | regulation of rhodopsin mediated signaling pathway(GO:0022400) |
| 0.0 | 0.4 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.0 | 0.4 | GO:0099612 | protein localization to axon(GO:0099612) |
| 0.0 | 0.4 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
| 0.0 | 0.9 | GO:0046627 | negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077) |
| 0.0 | 1.0 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.0 | 0.2 | GO:0098828 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.0 | 0.1 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 0.0 | 0.8 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
| 0.0 | 0.7 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
| 0.0 | 0.2 | GO:0021520 | spinal cord motor neuron cell fate specification(GO:0021520) |
| 0.0 | 0.4 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
| 0.0 | 0.2 | GO:0021794 | thalamus development(GO:0021794) |
| 0.0 | 0.7 | GO:0006465 | signal peptide processing(GO:0006465) |
| 0.0 | 1.1 | GO:2000249 | regulation of actin cytoskeleton reorganization(GO:2000249) |
| 0.0 | 0.5 | GO:0060219 | camera-type eye photoreceptor cell differentiation(GO:0060219) |
| 0.0 | 0.3 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
| 0.0 | 0.2 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 0.0 | 1.5 | GO:0032784 | regulation of DNA-templated transcription, elongation(GO:0032784) |
| 0.0 | 2.5 | GO:0061077 | chaperone-mediated protein folding(GO:0061077) |
| 0.0 | 0.6 | GO:0042118 | endothelial cell activation(GO:0042118) |
| 0.0 | 0.7 | GO:0014898 | muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898) |
| 0.0 | 0.4 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.0 | 2.4 | GO:1902600 | hydrogen ion transmembrane transport(GO:1902600) |
| 0.0 | 0.9 | GO:0035767 | endothelial cell chemotaxis(GO:0035767) |
| 0.0 | 0.4 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
| 0.0 | 0.1 | GO:0086048 | membrane depolarization during bundle of His cell action potential(GO:0086048) |
| 0.0 | 0.1 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
| 0.0 | 0.1 | GO:0045085 | negative regulation of interleukin-2 biosynthetic process(GO:0045085) |
| 0.0 | 0.1 | GO:0061113 | pancreas morphogenesis(GO:0061113) |
| 0.0 | 0.0 | GO:0061051 | positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051) |
| 0.0 | 0.1 | GO:0014052 | regulation of gamma-aminobutyric acid secretion(GO:0014052) |
| 0.0 | 0.4 | GO:1900273 | positive regulation of long-term synaptic potentiation(GO:1900273) |
| 0.0 | 0.5 | GO:0035635 | entry of bacterium into host cell(GO:0035635) endoplasmic reticulum mannose trimming(GO:1904380) |
| 0.0 | 0.2 | GO:0060576 | intestinal epithelial cell development(GO:0060576) |
| 0.0 | 0.4 | GO:1990001 | inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001) |
| 0.0 | 0.1 | GO:0070627 | ferrous iron import(GO:0070627) |
| 0.0 | 0.1 | GO:0032025 | response to cobalt ion(GO:0032025) |
| 0.0 | 0.1 | GO:0035962 | response to interleukin-13(GO:0035962) |
| 0.0 | 0.2 | GO:0038007 | netrin-activated signaling pathway(GO:0038007) |
| 0.0 | 1.5 | GO:0008344 | adult locomotory behavior(GO:0008344) |
| 0.0 | 0.1 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 0.0 | 0.1 | GO:0032819 | positive regulation of natural killer cell proliferation(GO:0032819) |
| 0.0 | 0.1 | GO:0031508 | pericentric heterochromatin assembly(GO:0031508) |
| 0.0 | 0.2 | GO:0031998 | regulation of fatty acid beta-oxidation(GO:0031998) |
| 0.0 | 0.2 | GO:0032802 | low-density lipoprotein particle receptor catabolic process(GO:0032802) |
| 0.0 | 0.1 | GO:0070427 | nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427) |
| 0.0 | 0.3 | GO:0051290 | protein heterotetramerization(GO:0051290) |
| 0.0 | 0.1 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
| 0.0 | 0.2 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.0 | 0.6 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
| 0.0 | 0.1 | GO:0071947 | protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) |
| 0.0 | 0.8 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.0 | 0.3 | GO:1904294 | positive regulation of ERAD pathway(GO:1904294) |
| 0.0 | 0.6 | GO:0061462 | protein localization to lysosome(GO:0061462) |
| 0.0 | 0.2 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 0.0 | 0.5 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.0 | 0.3 | GO:1903206 | negative regulation of hydrogen peroxide-induced cell death(GO:1903206) |
| 0.0 | 1.6 | GO:0001676 | long-chain fatty acid metabolic process(GO:0001676) |
| 0.0 | 0.0 | GO:0018312 | peptidyl-serine ADP-ribosylation(GO:0018312) |
| 0.0 | 0.4 | GO:0003416 | endochondral bone growth(GO:0003416) |
| 0.0 | 0.2 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
| 0.0 | 0.1 | GO:0035385 | Roundabout signaling pathway(GO:0035385) |
| 0.0 | 0.7 | GO:0034260 | negative regulation of GTPase activity(GO:0034260) |
| 0.0 | 0.4 | GO:0006308 | DNA catabolic process(GO:0006308) |
| 0.0 | 0.0 | GO:0072137 | condensed mesenchymal cell proliferation(GO:0072137) |
| 0.0 | 1.8 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.0 | 1.1 | GO:0030516 | regulation of axon extension(GO:0030516) |
| 0.0 | 0.1 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 0.0 | 0.0 | GO:0033326 | cerebrospinal fluid secretion(GO:0033326) |
| 0.0 | 0.5 | GO:0070266 | necroptotic process(GO:0070266) |
| 0.0 | 0.3 | GO:0042501 | serine phosphorylation of STAT protein(GO:0042501) |
| 0.0 | 0.2 | GO:0015871 | choline transport(GO:0015871) |
| 0.0 | 0.3 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 4.7 | GO:0031523 | Myb complex(GO:0031523) |
| 0.9 | 2.7 | GO:0036117 | hyaluranon cable(GO:0036117) |
| 0.6 | 2.6 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
| 0.6 | 1.7 | GO:0071062 | alphav-beta3 integrin-vitronectin complex(GO:0071062) |
| 0.6 | 1.7 | GO:0043259 | laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) |
| 0.5 | 2.2 | GO:0005889 | hydrogen:potassium-exchanging ATPase complex(GO:0005889) |
| 0.4 | 1.3 | GO:1990723 | cytoplasmic periphery of the nuclear pore complex(GO:1990723) |
| 0.3 | 1.7 | GO:0045160 | myosin I complex(GO:0045160) |
| 0.3 | 1.2 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
| 0.3 | 1.1 | GO:1990032 | parallel fiber(GO:1990032) |
| 0.3 | 2.3 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 0.2 | 3.5 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.2 | 0.8 | GO:1990356 | sumoylated E2 ligase complex(GO:1990356) |
| 0.2 | 1.5 | GO:0035976 | AP1 complex(GO:0035976) |
| 0.2 | 0.9 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 0.2 | 1.2 | GO:0035867 | alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) |
| 0.2 | 0.7 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 0.2 | 1.3 | GO:0032584 | growth cone membrane(GO:0032584) |
| 0.1 | 1.5 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 0.1 | 0.4 | GO:0071750 | dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752) |
| 0.1 | 1.0 | GO:0005956 | protein kinase CK2 complex(GO:0005956) |
| 0.1 | 3.7 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.1 | 1.1 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
| 0.1 | 1.9 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.1 | 2.5 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.1 | 0.5 | GO:0001651 | dense fibrillar component(GO:0001651) |
| 0.1 | 0.8 | GO:0000796 | condensin complex(GO:0000796) |
| 0.1 | 1.7 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.1 | 1.0 | GO:0045275 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.1 | 4.0 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.1 | 0.4 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.1 | 0.3 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
| 0.1 | 0.9 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 0.1 | 1.2 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.1 | 0.4 | GO:1990769 | proximal neuron projection(GO:1990769) |
| 0.1 | 0.7 | GO:0005587 | collagen type IV trimer(GO:0005587) |
| 0.1 | 1.0 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.1 | 0.6 | GO:0097425 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
| 0.1 | 0.6 | GO:0071986 | Ragulator complex(GO:0071986) |
| 0.1 | 1.4 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.1 | 2.2 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.1 | 0.5 | GO:0043541 | UDP-N-acetylglucosamine transferase complex(GO:0043541) |
| 0.1 | 1.7 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.1 | 6.7 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.1 | 0.5 | GO:0000801 | central element(GO:0000801) |
| 0.1 | 3.3 | GO:0000795 | synaptonemal complex(GO:0000795) |
| 0.1 | 0.4 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
| 0.1 | 0.3 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 0.1 | 5.5 | GO:0045095 | keratin filament(GO:0045095) |
| 0.1 | 1.4 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.1 | 0.3 | GO:1902560 | GMP reductase complex(GO:1902560) |
| 0.1 | 0.3 | GO:0036398 | TCR signalosome(GO:0036398) |
| 0.1 | 1.0 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.1 | 1.1 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.1 | 7.3 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.1 | 0.4 | GO:0061617 | MICOS complex(GO:0061617) |
| 0.1 | 1.1 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.0 | 0.4 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 0.0 | 0.9 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.0 | 0.7 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.0 | 1.9 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 0.5 | GO:0005638 | lamin filament(GO:0005638) |
| 0.0 | 0.7 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.0 | 0.6 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.0 | 0.4 | GO:0044327 | dendritic spine head(GO:0044327) |
| 0.0 | 1.0 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.0 | 0.6 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.0 | 0.3 | GO:0016589 | NURF complex(GO:0016589) |
| 0.0 | 0.2 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 0.0 | 3.0 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 0.6 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.0 | 0.3 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 0.0 | 0.2 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.0 | 1.0 | GO:0097381 | photoreceptor disc membrane(GO:0097381) |
| 0.0 | 0.4 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.0 | 0.3 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.0 | 0.7 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.0 | 0.7 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.0 | 1.0 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.0 | 0.5 | GO:0042555 | MCM complex(GO:0042555) |
| 0.0 | 0.5 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.0 | 0.4 | GO:0097433 | dense body(GO:0097433) |
| 0.0 | 0.4 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.0 | 0.1 | GO:1990590 | ATF1-ATF4 transcription factor complex(GO:1990590) |
| 0.0 | 3.8 | GO:0031985 | Golgi cisterna(GO:0031985) |
| 0.0 | 0.1 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.0 | 0.2 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.0 | 0.3 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.0 | 0.3 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
| 0.0 | 0.2 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 0.0 | 0.3 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 0.0 | 0.2 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 0.0 | 0.4 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.0 | 1.0 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.0 | 0.4 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.0 | 0.1 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 0.0 | 0.3 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 0.5 | GO:0031011 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
| 0.0 | 0.6 | GO:0000178 | exosome (RNase complex)(GO:0000178) |
| 0.0 | 0.2 | GO:0044194 | cytolytic granule(GO:0044194) |
| 0.0 | 0.6 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.0 | 1.2 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.0 | 0.9 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 2.0 | GO:0072686 | mitotic spindle(GO:0072686) |
| 0.0 | 2.9 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 1.1 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 0.5 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.0 | 1.5 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 0.5 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.0 | 0.2 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 0.0 | 0.5 | GO:0031231 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.0 | 0.5 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.0 | 0.2 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.0 | 0.2 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.0 | 1.0 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 0.2 | GO:0032039 | integrator complex(GO:0032039) |
| 0.0 | 0.1 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
| 0.0 | 0.8 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 0.4 | GO:0005795 | Golgi stack(GO:0005795) |
| 0.0 | 6.0 | GO:0045121 | membrane raft(GO:0045121) |
| 0.0 | 4.9 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 0.1 | GO:0031415 | NatA complex(GO:0031415) |
| 0.0 | 1.0 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.0 | 0.5 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 0.2 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.0 | 0.3 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.0 | 1.3 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.0 | 0.8 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.0 | 0.2 | GO:0031462 | Cul2-RING ubiquitin ligase complex(GO:0031462) |
| 0.0 | 0.8 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 0.7 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 0.6 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.0 | 0.2 | GO:0031083 | BLOC-1 complex(GO:0031083) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 3.8 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 0.7 | 2.2 | GO:0030290 | sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428) |
| 0.6 | 3.1 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 0.6 | 3.5 | GO:0016314 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314) |
| 0.5 | 1.6 | GO:0034602 | oxoglutarate dehydrogenase (NAD+) activity(GO:0034602) |
| 0.5 | 1.9 | GO:0070320 | inward rectifier potassium channel inhibitor activity(GO:0070320) |
| 0.5 | 1.4 | GO:0047389 | glycerophosphocholine phosphodiesterase activity(GO:0047389) |
| 0.4 | 1.8 | GO:0017089 | glycolipid transporter activity(GO:0017089) |
| 0.4 | 1.3 | GO:0004021 | L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635) |
| 0.4 | 2.6 | GO:0004656 | procollagen-proline 4-dioxygenase activity(GO:0004656) |
| 0.4 | 1.2 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
| 0.4 | 4.4 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.4 | 2.6 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
| 0.3 | 1.3 | GO:0004001 | adenosine kinase activity(GO:0004001) |
| 0.3 | 1.0 | GO:0004639 | phosphoribosylaminoimidazole carboxylase activity(GO:0004638) phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639) |
| 0.3 | 1.5 | GO:0004370 | glycerol kinase activity(GO:0004370) |
| 0.3 | 0.9 | GO:0004874 | aryl hydrocarbon receptor activity(GO:0004874) |
| 0.3 | 0.3 | GO:0000247 | C-8 sterol isomerase activity(GO:0000247) |
| 0.3 | 1.1 | GO:0015563 | uptake transmembrane transporter activity(GO:0015563) |
| 0.3 | 3.3 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.3 | 1.9 | GO:0004169 | dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169) |
| 0.3 | 0.8 | GO:0034739 | histone deacetylase activity (H4-K16 specific)(GO:0034739) |
| 0.3 | 1.3 | GO:0033906 | hyaluronoglucuronidase activity(GO:0033906) |
| 0.3 | 1.3 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
| 0.3 | 2.3 | GO:0043184 | vascular endothelial growth factor receptor 2 binding(GO:0043184) |
| 0.3 | 1.0 | GO:0051500 | D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500) |
| 0.3 | 0.8 | GO:0005477 | pyruvate secondary active transmembrane transporter activity(GO:0005477) |
| 0.3 | 0.3 | GO:0005128 | erythropoietin receptor binding(GO:0005128) |
| 0.2 | 1.1 | GO:0031493 | nucleosomal histone binding(GO:0031493) |
| 0.2 | 1.1 | GO:0005152 | interleukin-1 receptor antagonist activity(GO:0005152) |
| 0.2 | 0.7 | GO:0033981 | D-dopachrome decarboxylase activity(GO:0033981) |
| 0.2 | 2.2 | GO:0017169 | CDP-alcohol phosphatidyltransferase activity(GO:0017169) |
| 0.2 | 2.3 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.2 | 0.8 | GO:0061656 | SUMO conjugating enzyme activity(GO:0061656) |
| 0.2 | 1.8 | GO:0036042 | long-chain fatty acyl-CoA binding(GO:0036042) |
| 0.2 | 1.5 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 0.2 | 1.0 | GO:0050254 | rhodopsin kinase activity(GO:0050254) |
| 0.2 | 1.3 | GO:0034046 | poly(G) binding(GO:0034046) |
| 0.2 | 1.1 | GO:0031962 | mineralocorticoid receptor binding(GO:0031962) |
| 0.2 | 0.9 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 0.2 | 0.5 | GO:0050509 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
| 0.2 | 1.6 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.2 | 4.7 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.2 | 1.4 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.2 | 0.7 | GO:0004609 | phosphatidylserine decarboxylase activity(GO:0004609) |
| 0.2 | 0.5 | GO:1990259 | protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259) |
| 0.2 | 2.7 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.2 | 0.6 | GO:0004769 | steroid delta-isomerase activity(GO:0004769) |
| 0.2 | 1.4 | GO:0043426 | MRF binding(GO:0043426) |
| 0.2 | 0.5 | GO:0004608 | phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101) |
| 0.2 | 1.3 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.2 | 1.2 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.1 | 3.4 | GO:0098748 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.1 | 0.4 | GO:0070984 | SET domain binding(GO:0070984) |
| 0.1 | 0.4 | GO:0004492 | methylmalonyl-CoA decarboxylase activity(GO:0004492) |
| 0.1 | 0.8 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
| 0.1 | 0.6 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 0.1 | 3.2 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
| 0.1 | 0.4 | GO:0050252 | retinol O-fatty-acyltransferase activity(GO:0050252) |
| 0.1 | 1.1 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.1 | 1.2 | GO:0030621 | U4 snRNA binding(GO:0030621) |
| 0.1 | 0.9 | GO:0004445 | inositol-polyphosphate 5-phosphatase activity(GO:0004445) |
| 0.1 | 0.8 | GO:0047045 | testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045) |
| 0.1 | 3.6 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.1 | 0.9 | GO:0004396 | glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 0.1 | 0.4 | GO:0032450 | maltose alpha-glucosidase activity(GO:0032450) |
| 0.1 | 0.9 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.1 | 2.1 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.1 | 0.3 | GO:0098918 | structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973) |
| 0.1 | 0.6 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
| 0.1 | 1.6 | GO:0032052 | bile acid binding(GO:0032052) |
| 0.1 | 0.6 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 0.1 | 0.3 | GO:0001716 | L-amino-acid oxidase activity(GO:0001716) |
| 0.1 | 1.4 | GO:0046790 | virion binding(GO:0046790) |
| 0.1 | 0.5 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
| 0.1 | 0.9 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
| 0.1 | 1.6 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.1 | 0.4 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.1 | 0.8 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.1 | 1.6 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.1 | 1.4 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.1 | 0.5 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
| 0.1 | 5.1 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.1 | 0.3 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 0.1 | 0.2 | GO:0036361 | racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661) |
| 0.1 | 0.4 | GO:0032564 | adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564) |
| 0.1 | 0.2 | GO:0030549 | acetylcholine receptor activator activity(GO:0030549) |
| 0.1 | 1.0 | GO:0045159 | myosin II binding(GO:0045159) |
| 0.1 | 0.5 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 0.1 | 0.7 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.1 | 2.4 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.1 | 0.8 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.1 | 0.4 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.1 | 1.2 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.1 | 0.2 | GO:0004420 | hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282) |
| 0.1 | 2.0 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.1 | 1.2 | GO:0048185 | activin binding(GO:0048185) |
| 0.1 | 0.4 | GO:0001515 | opioid peptide activity(GO:0001515) |
| 0.1 | 1.6 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
| 0.1 | 0.8 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.1 | 0.3 | GO:0003920 | GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657) |
| 0.1 | 0.4 | GO:0032217 | riboflavin transporter activity(GO:0032217) |
| 0.1 | 0.3 | GO:0047696 | beta-adrenergic receptor kinase activity(GO:0047696) |
| 0.1 | 0.5 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.0 | 1.0 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.0 | 0.3 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
| 0.0 | 0.4 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 0.0 | 0.3 | GO:0005298 | proline:sodium symporter activity(GO:0005298) |
| 0.0 | 0.2 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
| 0.0 | 0.9 | GO:0008296 | 3'-5'-exodeoxyribonuclease activity(GO:0008296) |
| 0.0 | 1.2 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.0 | 0.1 | GO:0047783 | steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783) |
| 0.0 | 0.4 | GO:0033170 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.0 | 0.1 | GO:0086059 | voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059) |
| 0.0 | 0.8 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.0 | 0.5 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
| 0.0 | 0.3 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.0 | 1.6 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.0 | 1.0 | GO:0043495 | protein anchor(GO:0043495) |
| 0.0 | 5.7 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.4 | GO:0102336 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.0 | 0.4 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.0 | 0.6 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.0 | 0.5 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 0.0 | 0.2 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
| 0.0 | 1.1 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.0 | 0.9 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.0 | 1.3 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.0 | 0.3 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.0 | 3.2 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 11.5 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 0.3 | GO:0004514 | nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514) |
| 0.0 | 0.2 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
| 0.0 | 0.4 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.0 | 3.6 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.0 | 0.3 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.0 | 1.1 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.0 | 2.5 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 1.0 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.0 | 0.1 | GO:0004991 | parathyroid hormone receptor activity(GO:0004991) |
| 0.0 | 0.6 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
| 0.0 | 1.0 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.0 | 0.2 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 0.0 | 1.9 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 0.3 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.0 | 0.5 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.0 | 0.2 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
| 0.0 | 0.4 | GO:1901612 | cardiolipin binding(GO:1901612) |
| 0.0 | 0.3 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.0 | 0.2 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.0 | 2.6 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 0.5 | GO:0030275 | LRR domain binding(GO:0030275) |
| 0.0 | 0.2 | GO:0005168 | neurotrophin TRKA receptor binding(GO:0005168) |
| 0.0 | 0.1 | GO:0023029 | MHC class Ib protein binding(GO:0023029) |
| 0.0 | 0.3 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.0 | 0.4 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.0 | 0.5 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.0 | 0.3 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.0 | 0.4 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.0 | 0.2 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.0 | 0.2 | GO:0004957 | prostaglandin E receptor activity(GO:0004957) |
| 0.0 | 0.1 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
| 0.0 | 1.7 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 0.1 | GO:0031728 | CCR3 chemokine receptor binding(GO:0031728) |
| 0.0 | 1.5 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.0 | 1.7 | GO:0009055 | electron carrier activity(GO:0009055) |
| 0.0 | 0.7 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 0.8 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.0 | 2.3 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 0.6 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.0 | 0.2 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
| 0.0 | 0.7 | GO:0043531 | ADP binding(GO:0043531) |
| 0.0 | 0.2 | GO:0004559 | alpha-mannosidase activity(GO:0004559) |
| 0.0 | 0.9 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 0.1 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 0.0 | 0.8 | GO:0061650 | ubiquitin-like protein conjugating enzyme activity(GO:0061650) |
| 0.0 | 0.1 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
| 0.0 | 0.4 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.0 | 0.3 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.0 | 0.4 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.0 | 0.2 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 0.0 | 0.3 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.0 | 1.4 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 0.0 | 0.2 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.0 | 0.3 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.0 | 0.4 | GO:0070003 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 0.1 | GO:1903136 | cuprous ion binding(GO:1903136) |
| 0.0 | 0.7 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.0 | 1.1 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.0 | 0.1 | GO:0005412 | glucose:sodium symporter activity(GO:0005412) |
| 0.0 | 0.3 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
| 0.0 | 0.1 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
| 0.0 | 0.3 | GO:0045503 | dynein light chain binding(GO:0045503) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.1 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.2 | 7.9 | ST INTERLEUKIN 4 PATHWAY | Interleukin 4 (IL-4) Pathway |
| 0.2 | 4.9 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
| 0.1 | 2.1 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.1 | 1.7 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.1 | 1.7 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.1 | 2.4 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.1 | 5.0 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.1 | 0.9 | SA TRKA RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.1 | 3.0 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.1 | 3.9 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 0.8 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.0 | 0.4 | SIG IL4RECEPTOR IN B LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.0 | 2.7 | PID ER NONGENOMIC PATHWAY | Plasma membrane estrogen receptor signaling |
| 0.0 | 2.1 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.0 | 0.3 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.0 | 1.7 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 0.7 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.0 | 0.5 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.0 | 0.8 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.0 | 1.5 | PID IL2 1PATHWAY | IL2-mediated signaling events |
| 0.0 | 1.1 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.0 | 0.9 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.0 | 1.0 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.0 | 3.7 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 3.7 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 0.7 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 1.3 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.0 | 1.3 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 0.6 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.0 | 0.8 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 1.3 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 1.7 | PID CXCR4 PATHWAY | CXCR4-mediated signaling events |
| 0.0 | 9.2 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 2.5 | PID PDGFRB PATHWAY | PDGFR-beta signaling pathway |
| 0.0 | 0.5 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.0 | 0.6 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.0 | 0.2 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 0.0 | 0.8 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 0.8 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 0.7 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.0 | 0.4 | ST G ALPHA I PATHWAY | G alpha i Pathway |
| 0.0 | 0.1 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
| 0.0 | 0.4 | ST T CELL SIGNAL TRANSDUCTION | T Cell Signal Transduction |
| 0.0 | 0.4 | PID ATR PATHWAY | ATR signaling pathway |
| 0.0 | 0.7 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 0.3 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.0 | 1.1 | PID P73PATHWAY | p73 transcription factor network |
| 0.0 | 0.5 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 0.1 | PID CXCR3 PATHWAY | CXCR3-mediated signaling events |
| 0.0 | 0.3 | PID IL23 PATHWAY | IL23-mediated signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.1 | REACTOME SIGNALLING TO P38 VIA RIT AND RIN | Genes involved in Signalling to p38 via RIT and RIN |
| 0.2 | 5.2 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.2 | 3.1 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.1 | 3.5 | REACTOME SHC MEDIATED SIGNALLING | Genes involved in SHC-mediated signalling |
| 0.1 | 2.0 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.1 | 1.9 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.1 | 6.1 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.1 | 2.5 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.1 | 5.2 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.1 | 0.4 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 0.1 | 1.2 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.1 | 1.6 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.1 | 1.2 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.1 | 3.0 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
| 0.1 | 2.2 | REACTOME ENOS ACTIVATION AND REGULATION | Genes involved in eNOS activation and regulation |
| 0.1 | 2.6 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.1 | 1.0 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.1 | 2.7 | REACTOME SIGNAL TRANSDUCTION BY L1 | Genes involved in Signal transduction by L1 |
| 0.1 | 0.9 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.1 | 1.6 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.1 | 1.0 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.1 | 0.8 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.1 | 1.3 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.1 | 1.5 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.1 | 1.6 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.1 | 1.2 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.1 | 1.9 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.1 | 0.6 | REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.0 | 1.4 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.0 | 2.5 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.0 | 1.3 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.0 | 2.0 | REACTOME TRIGLYCERIDE BIOSYNTHESIS | Genes involved in Triglyceride Biosynthesis |
| 0.0 | 0.5 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.0 | 1.8 | REACTOME GROWTH HORMONE RECEPTOR SIGNALING | Genes involved in Growth hormone receptor signaling |
| 0.0 | 5.2 | REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
| 0.0 | 0.9 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.0 | 1.3 | REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI | Genes involved in RIP-mediated NFkB activation via DAI |
| 0.0 | 1.5 | REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN | Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein |
| 0.0 | 0.4 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.0 | 0.7 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.0 | 1.3 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 1.9 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.0 | 0.6 | REACTOME POL SWITCHING | Genes involved in Polymerase switching |
| 0.0 | 0.6 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 0.0 | 0.6 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 0.5 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.0 | 1.3 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.0 | 0.5 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.0 | 1.2 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 2.7 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 1.0 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.0 | 0.5 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.0 | 1.1 | REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
| 0.0 | 0.4 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.0 | 0.4 | REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| 0.0 | 0.7 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 2.3 | REACTOME LATE PHASE OF HIV LIFE CYCLE | Genes involved in Late Phase of HIV Life Cycle |
| 0.0 | 0.2 | REACTOME ADP SIGNALLING THROUGH P2RY1 | Genes involved in ADP signalling through P2Y purinoceptor 1 |
| 0.0 | 1.6 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.0 | 0.4 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.0 | 1.3 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.0 | 0.5 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.0 | 0.9 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.0 | 0.6 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.0 | 0.4 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
| 0.0 | 1.7 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.0 | 0.4 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.0 | 0.2 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 0.0 | 0.9 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.0 | 0.9 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 1.1 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 0.4 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.0 | 0.5 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.0 | 0.3 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.0 | 1.0 | REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH | Genes involved in NCAM signaling for neurite out-growth |
| 0.0 | 0.6 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 0.2 | REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
| 0.0 | 0.3 | REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 0.0 | 0.3 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
| 0.0 | 0.3 | REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
| 0.0 | 0.3 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.0 | 0.5 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 0.4 | REACTOME SPHINGOLIPID METABOLISM | Genes involved in Sphingolipid metabolism |