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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for SHOX

Z-value: 0.69

Motif logo

Transcription factors associated with SHOX

Gene Symbol Gene ID Gene Info
ENSG00000185960.14 SHOX
ENSG00000185960.14 SHOX

Activity profile of SHOX motif

Sorted Z-values of SHOX motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SHOX

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr4_+_68447453 3.90 ENST00000305363.9
transmembrane serine protease 11E
chr1_-_152414256 3.29 ENST00000271835.3
cornulin
chr4_-_56681288 2.36 ENST00000556376.6
ENST00000420433.6
HOP homeobox
chr4_-_56681588 2.36 ENST00000554144.5
ENST00000381260.7
HOP homeobox
chr12_-_89352395 2.14 ENST00000308385.6
dual specificity phosphatase 6
chr1_-_16978276 2.04 ENST00000375534.7
microfibril associated protein 2
chr7_-_41703062 1.98 ENST00000242208.5
inhibin subunit beta A
chr12_-_89352487 1.96 ENST00000548755.1
ENST00000279488.8
dual specificity phosphatase 6
chr2_-_207167220 1.90 ENST00000421199.5
ENST00000457962.5
Kruppel like factor 7
chr8_+_32647080 1.56 ENST00000520502.7
ENST00000523041.2
ENST00000650819.1
neuregulin 1
chr13_+_77535681 1.42 ENST00000349847.4
sciellin
chr13_+_77535669 1.41 ENST00000535157.5
sciellin
chr13_+_77535742 1.41 ENST00000377246.7
sciellin
chr14_-_55191534 1.40 ENST00000395425.6
ENST00000247191.7
DLG associated protein 5
chr12_-_27970047 1.38 ENST00000395868.7
parathyroid hormone like hormone
chr9_+_122371036 1.37 ENST00000619306.5
ENST00000426608.6
ENST00000223423.8
prostaglandin-endoperoxide synthase 1
chrX_-_154371210 1.37 ENST00000369856.8
ENST00000422373.6
ENST00000360319.9
filamin A
chr9_-_120877026 1.29 ENST00000436309.5
PHD finger protein 19
chr2_+_209579598 1.25 ENST00000445941.5
ENST00000673860.1
microtubule associated protein 2
chr11_+_33039996 1.17 ENST00000432887.5
ENST00000528898.1
ENST00000531632.6
t-complex 11 like 1
chr7_-_13986439 1.17 ENST00000443608.5
ENST00000438956.5
ETS variant transcription factor 1
chr12_-_27970273 1.16 ENST00000542963.1
ENST00000535992.5
parathyroid hormone like hormone
chr5_+_31193739 1.13 ENST00000514738.5
cadherin 6
chr19_-_51019699 1.10 ENST00000358789.8
kallikrein related peptidase 10
chr13_+_108629605 1.08 ENST00000457511.7
myosin XVI
chr20_+_43667105 1.08 ENST00000217026.5
MYB proto-oncogene like 2
chr19_-_51034727 1.07 ENST00000525263.5
kallikrein related peptidase 12
chr4_-_68245683 1.04 ENST00000332644.6
transmembrane serine protease 11B
chr2_+_157257687 1.04 ENST00000259056.5
polypeptide N-acetylgalactosaminyltransferase 5
chr10_-_29736956 1.00 ENST00000674475.1
supervillin
chr19_-_51034993 0.99 ENST00000684732.1
kallikrein related peptidase 12
chr9_+_122371014 0.98 ENST00000362012.7
prostaglandin-endoperoxide synthase 1
chr19_-_51034840 0.98 ENST00000529888.5
kallikrein related peptidase 12
chr5_+_31193678 0.98 ENST00000265071.3
cadherin 6
chr19_-_51034892 0.97 ENST00000319590.8
ENST00000250351.4
kallikrein related peptidase 12
chr18_+_36544544 0.96 ENST00000591635.5
formin homology 2 domain containing 3
chr4_+_168092530 0.96 ENST00000359299.8
annexin A10
chr3_+_122055355 0.94 ENST00000330540.7
ENST00000469710.5
ENST00000493101.5
CD86 molecule
chr12_+_26195313 0.93 ENST00000422622.3
sarcospan
chr15_+_41286011 0.92 ENST00000661438.1
novel protein
chr9_-_120877167 0.90 ENST00000373896.8
ENST00000312189.10
PHD finger protein 19
chr3_-_52056552 0.89 ENST00000495880.2
dual specificity phosphatase 7
chr12_+_26195647 0.89 ENST00000535504.1
sarcospan
chr1_+_209704836 0.88 ENST00000367027.5
hydroxysteroid 11-beta dehydrogenase 1
chr3_+_159069252 0.84 ENST00000640015.1
ENST00000476809.7
ENST00000485419.7
IQCJ-SCHIP1 readthrough
chr4_-_142305935 0.84 ENST00000511838.5
inositol polyphosphate-4-phosphatase type II B
chr16_+_69105636 0.80 ENST00000569188.6
hyaluronan synthase 3
chr2_-_189179754 0.79 ENST00000374866.9
ENST00000618828.1
collagen type V alpha 2 chain
chr3_+_172754457 0.78 ENST00000441497.6
epithelial cell transforming 2
chr3_+_130850585 0.77 ENST00000505330.5
ENST00000504381.5
ENST00000507488.6
ATPase secretory pathway Ca2+ transporting 1
chr19_-_51020154 0.76 ENST00000391805.5
ENST00000599077.1
kallikrein related peptidase 10
chr7_-_93117956 0.76 ENST00000446617.1
ENST00000379958.3
ENST00000620985.4
sterile alpha motif domain containing 9
chr6_-_32190170 0.76 ENST00000375050.6
PBX homeobox 2
chr2_+_90038848 0.76 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr18_+_24460655 0.75 ENST00000426880.2
histamine receptor H4
chr5_+_53480619 0.75 ENST00000396947.7
ENST00000256759.8
follistatin
chr17_+_59155726 0.73 ENST00000578777.5
ENST00000577457.1
ENST00000582995.5
ENST00000262293.9
ENST00000614081.1
proline rich 11
chr12_+_26195543 0.73 ENST00000242729.7
sarcospan
chr5_-_126595237 0.72 ENST00000637206.1
ENST00000553117.5
aldehyde dehydrogenase 7 family member A1
chr10_-_29634964 0.71 ENST00000375398.6
ENST00000355867.8
supervillin
chr12_-_56741535 0.69 ENST00000647707.1
novel protein
chr1_-_93681829 0.67 ENST00000260502.11
BCAR3 adaptor protein, NSP family member
chr17_-_66229380 0.67 ENST00000205948.11
apolipoprotein H
chr4_+_168497066 0.67 ENST00000261509.10
palladin, cytoskeletal associated protein
chr8_+_22567038 0.67 ENST00000523348.1
sorbin and SH3 domain containing 3
chr19_-_51020019 0.66 ENST00000309958.7
kallikrein related peptidase 10
chr7_+_77798750 0.66 ENST00000416283.6
ENST00000422959.6
ENST00000307305.12
ENST00000424760.5
putative homeodomain transcription factor 2
chr5_+_127649018 0.65 ENST00000379445.7
cortexin 3
chr7_+_134891400 0.65 ENST00000393118.6
caldesmon 1
chr10_-_14330879 0.64 ENST00000357447.7
FERM domain containing 4A
chr3_+_111999326 0.64 ENST00000494932.1
transgelin 3
chr8_+_32646838 0.64 ENST00000651333.1
ENST00000652592.1
neuregulin 1
chr15_+_92900338 0.63 ENST00000625990.3
chromodomain helicase DNA binding protein 2
chr17_-_9791586 0.62 ENST00000571134.2
dehydrogenase/reductase 7C
chrX_-_72239022 0.62 ENST00000373657.2
ENST00000334463.4
ERCC excision repair 6 like, spindle assembly checkpoint helicase
chr12_+_28257195 0.61 ENST00000381259.5
coiled-coil domain containing 91
chr17_-_40994159 0.60 ENST00000391586.3
keratin associated protein 3-3
chr18_+_23992773 0.60 ENST00000304621.10
tetratricopeptide repeat domain 39C
chr20_-_52105644 0.60 ENST00000371523.8
ZFP64 zinc finger protein
chr12_-_9869345 0.60 ENST00000228438.3
C-type lectin domain family 2 member B
chr7_+_77798832 0.58 ENST00000415251.6
ENST00000275575.11
putative homeodomain transcription factor 2
chr4_+_168497044 0.58 ENST00000505667.6
palladin, cytoskeletal associated protein
chr2_-_40453438 0.57 ENST00000455476.5
solute carrier family 8 member A1
chr7_-_28180735 0.57 ENST00000283928.10
JAZF zinc finger 1
chr15_+_74788542 0.56 ENST00000567571.5
C-terminal Src kinase
chr2_+_170178136 0.55 ENST00000409044.7
ENST00000408978.9
myosin IIIB
chr16_+_11965193 0.55 ENST00000053243.6
ENST00000396495.3
TNF receptor superfamily member 17
chr7_-_13986498 0.55 ENST00000420159.6
ENST00000399357.7
ENST00000403527.5
ETS variant transcription factor 1
chr6_-_127459364 0.55 ENST00000487331.2
ENST00000483725.8
KIAA0408
chr12_+_93571832 0.54 ENST00000549887.1
suppressor of cytokine signaling 2
chr4_-_20984011 0.53 ENST00000382149.9
potassium voltage-gated channel interacting protein 4
chrX_+_108044967 0.53 ENST00000415430.7
V-set and immunoglobulin domain containing 1
chr1_-_68232539 0.53 ENST00000370976.7
ENST00000354777.6
Wnt ligand secretion mediator
chr12_-_56934403 0.53 ENST00000293502.2
short chain dehydrogenase/reductase family 9C member 7
chr10_-_54801179 0.53 ENST00000373955.5
protocadherin related 15
chr2_+_200308943 0.52 ENST00000619961.4
spermatogenesis associated serine rich 2 like
chr6_+_121437378 0.52 ENST00000650427.1
ENST00000647564.1
gap junction protein alpha 1
chr17_-_41118369 0.52 ENST00000391413.4
keratin associated protein 4-11
chrX_+_108045050 0.52 ENST00000458383.1
ENST00000217957.10
V-set and immunoglobulin domain containing 1
chr3_+_111998739 0.52 ENST00000393917.6
ENST00000273368.8
transgelin 3
chr18_+_24460630 0.50 ENST00000256906.5
histamine receptor H4
chr1_-_93614091 0.50 ENST00000370247.7
BCAR3 adaptor protein, NSP family member
chr3_+_111999189 0.50 ENST00000455401.6
transgelin 3
chr2_-_162152404 0.50 ENST00000375497.3
glucagon
chr12_-_16608183 0.49 ENST00000354662.5
ENST00000538051.5
LIM domain only 3
chr7_-_13989658 0.49 ENST00000430479.6
ENST00000433547.1
ENST00000405192.6
ETS variant transcription factor 1
chr10_+_18400562 0.48 ENST00000377315.5
ENST00000650685.1
calcium voltage-gated channel auxiliary subunit beta 2
chr9_+_122370523 0.48 ENST00000643810.1
ENST00000540753.6
prostaglandin-endoperoxide synthase 1
chrX_+_100584928 0.48 ENST00000373031.5
tenomodulin
chr3_-_98517096 0.47 ENST00000513873.1
claudin domain containing 1
chr10_+_123135938 0.47 ENST00000357878.7
H6 family homeobox 3
chr6_-_111606260 0.46 ENST00000340026.10
TRAF3 interacting protein 2
chr4_-_39977836 0.46 ENST00000303538.13
ENST00000503396.5
PDS5 cohesin associated factor A
chr7_-_87713287 0.46 ENST00000416177.1
ENST00000265724.8
ENST00000543898.5
ATP binding cassette subfamily B member 1
chr12_+_93571664 0.45 ENST00000622746.4
ENST00000548537.1
suppressor of cytokine signaling 2
chr2_+_186694007 0.45 ENST00000304698.10
family with sequence similarity 171 member B
chr13_-_35476682 0.45 ENST00000379919.6
mab-21 like 1
chr4_-_151227881 0.44 ENST00000652233.1
ENST00000514152.5
SH3 domain containing 19
chr3_-_33645433 0.44 ENST00000635664.1
ENST00000485378.6
ENST00000313350.10
ENST00000487200.5
cytoplasmic linker associated protein 2
chr12_-_52573816 0.44 ENST00000549343.5
ENST00000305620.3
keratin 74
chr3_-_151316795 0.44 ENST00000260843.5
G protein-coupled receptor 87
chr12_-_27972725 0.44 ENST00000545234.6
parathyroid hormone like hormone
chr3_+_111998915 0.44 ENST00000478951.6
transgelin 3
chr6_+_29099490 0.43 ENST00000641659.2
olfactory receptor family 2 subfamily J member 1
chr12_+_18261511 0.43 ENST00000538779.6
ENST00000433979.6
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr6_+_41053194 0.43 ENST00000244669.3
apolipoprotein B mRNA editing enzyme catalytic subunit 2
chrX_+_43656289 0.42 ENST00000338702.4
monoamine oxidase A
chr1_-_27604176 0.42 ENST00000642416.1
AT-hook DNA binding motif containing 1
chr2_+_68734773 0.42 ENST00000409202.8
Rho GTPase activating protein 25
chr6_+_106360668 0.41 ENST00000633556.3
crystallin beta-gamma domain containing 1
chr2_-_24328113 0.41 ENST00000622089.4
intersectin 2
chr2_+_87338511 0.41 ENST00000421835.2
immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr1_-_27604135 0.41 ENST00000673934.1
ENST00000642245.1
AT-hook DNA binding motif containing 1
chr2_-_88979016 0.40 ENST00000390247.2
immunoglobulin kappa variable 3-7 (non-functional)
chr11_-_111923722 0.40 ENST00000527950.5
crystallin alpha B
chr15_-_55270280 0.39 ENST00000564609.5
RAB27A, member RAS oncogene family
chr11_-_117877463 0.39 ENST00000527717.5
FXYD domain containing ion transport regulator 6
chr2_+_90234809 0.39 ENST00000443397.5
immunoglobulin kappa variable 3D-7
chr2_-_65366650 0.39 ENST00000443619.6
sprouty related EVH1 domain containing 2
chr3_-_74521140 0.39 ENST00000263665.6
contactin 3
chr15_+_92900189 0.39 ENST00000626874.2
ENST00000627622.1
ENST00000629346.2
ENST00000628375.2
ENST00000420239.7
ENST00000394196.9
chromodomain helicase DNA binding protein 2
chr12_-_16608073 0.39 ENST00000441439.6
LIM domain only 3
chr7_+_116222804 0.38 ENST00000393481.6
testin LIM domain protein
chr14_-_106038355 0.38 ENST00000390597.3
immunoglobulin heavy variable 2-5
chr4_+_87608529 0.38 ENST00000651931.1
dentin sialophosphoprotein
chr15_-_55270874 0.38 ENST00000567380.5
ENST00000565972.5
ENST00000569493.5
RAB27A, member RAS oncogene family
chr10_+_18340821 0.37 ENST00000612743.1
ENST00000612134.4
calcium voltage-gated channel auxiliary subunit beta 2
chr8_+_7881387 0.37 ENST00000314357.4
defensin beta 103A
chr4_-_115113614 0.37 ENST00000264363.7
N-deacetylase and N-sulfotransferase 4
chr15_+_58138368 0.37 ENST00000219919.9
ENST00000536493.1
aquaporin 9
chr17_-_41055211 0.36 ENST00000542910.1
ENST00000398477.1
keratin associated protein 2-2
chr9_-_37025733 0.36 ENST00000651550.1
paired box 5
chr12_-_54259531 0.36 ENST00000550411.5
ENST00000439541.6
chromobox 5
chr12_-_86256299 0.36 ENST00000552808.6
ENST00000547225.5
MGAT4 family member C
chr8_+_104223320 0.36 ENST00000339750.3
regulating synaptic membrane exocytosis 2
chr7_+_50308672 0.36 ENST00000439701.2
ENST00000438033.5
ENST00000492782.6
IKAROS family zinc finger 1
chr10_+_18340699 0.36 ENST00000377329.10
calcium voltage-gated channel auxiliary subunit beta 2
chr3_+_153162196 0.36 ENST00000323534.5
RAP2B, member of RAS oncogene family
chr3_-_57199938 0.36 ENST00000473921.2
ENST00000295934.8
HESX homeobox 1
chr1_+_74235377 0.35 ENST00000326637.8
TNNI3 interacting kinase
chr2_+_90172802 0.35 ENST00000390277.3
immunoglobulin kappa variable 3D-11
chr15_+_21579912 0.35 ENST00000628444.1
long intergenic non-protein coding RNA 2203
chr12_-_3753091 0.35 ENST00000252322.1
ENST00000440314.7
calcium release activated channel regulator 2A
chr6_+_72212887 0.34 ENST00000523963.5
regulating synaptic membrane exocytosis 1
chr6_-_34146080 0.34 ENST00000538487.7
ENST00000374181.8
glutamate metabotropic receptor 4
chr12_+_119668109 0.34 ENST00000229328.10
ENST00000630317.1
protein kinase AMP-activated non-catalytic subunit beta 1
chr9_+_69145463 0.34 ENST00000636438.1
tight junction protein 2
chr14_+_22508602 0.34 ENST00000390504.1
T cell receptor alpha joining 33
chr3_-_167474026 0.34 ENST00000466903.1
ENST00000264677.8
serpin family I member 2
chr2_-_181680490 0.34 ENST00000684145.1
ENST00000295108.4
ENST00000684079.1
ENST00000683430.1
ceramide kinase like
neuronal differentiation 1
chr6_+_130018565 0.34 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL histone methyl-lysine binding protein 3
chr8_-_42768602 0.33 ENST00000534622.5
cholinergic receptor nicotinic alpha 6 subunit
chr14_+_32329341 0.33 ENST00000557354.5
ENST00000557102.1
ENST00000557272.1
A-kinase anchoring protein 6
chr12_-_118359639 0.33 ENST00000541786.5
ENST00000419821.6
ENST00000541878.5
TAO kinase 3
chr17_-_41065879 0.33 ENST00000394015.3
keratin associated protein 2-4
chr20_+_2295994 0.33 ENST00000381458.6
transglutaminase 3
chr11_-_47594399 0.32 ENST00000302514.4
C1q and TNF related 4
chr6_-_31139063 0.32 ENST00000259845.5
psoriasis susceptibility 1 candidate 2
chr4_-_142305826 0.32 ENST00000514525.1
inositol polyphosphate-4-phosphatase type II B
chr6_+_29111560 0.31 ENST00000377169.2
olfactory receptor family 2 subfamily J member 3
chr6_+_72212802 0.31 ENST00000401910.7
regulating synaptic membrane exocytosis 1
chr16_+_24729692 0.31 ENST00000315183.11
trinucleotide repeat containing adaptor 6A
chrX_+_7219431 0.31 ENST00000674499.1
ENST00000217961.5
steroid sulfatase
chr18_-_63158208 0.30 ENST00000678301.1
BCL2 apoptosis regulator
chr5_-_83720813 0.30 ENST00000515590.1
ENST00000274341.9
hyaluronan and proteoglycan link protein 1
chr4_+_70334963 0.30 ENST00000273936.6
calcium binding protein, spermatid associated 1
chr7_+_154305105 0.30 ENST00000332007.7
dipeptidyl peptidase like 6
chr5_+_120531464 0.29 ENST00000505123.5
proline rich 16
chr1_+_153774210 0.29 ENST00000271857.6
solute carrier family 27 member 3
chr9_+_107306459 0.29 ENST00000457811.1
RAD23 homolog B, nucleotide excision repair protein
chr1_+_154429315 0.29 ENST00000476006.5
interleukin 6 receptor
chr6_+_113857333 0.28 ENST00000612661.2
myristoylated alanine rich protein kinase C substrate
chr2_+_176122712 0.28 ENST00000249499.8
homeobox D9
chr13_-_75366973 0.28 ENST00000648194.1
TBC1 domain family member 4
chr11_-_117876892 0.27 ENST00000539526.5
FXYD domain containing ion transport regulator 6
chr7_-_22193824 0.27 ENST00000401957.6
Rap guanine nucleotide exchange factor 5
chr16_-_18876305 0.27 ENST00000563235.5
SMG1 nonsense mediated mRNA decay associated PI3K related kinase
chr14_+_64986846 0.27 ENST00000246166.3
farnesyltransferase, CAAX box, beta
chr4_-_76007501 0.26 ENST00000264888.6
C-X-C motif chemokine ligand 9
chr8_-_33599935 0.26 ENST00000523956.1
ENST00000256261.9
dual specificity phosphatase 26

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.7 2.0 GO:0060279 positive regulation of ovulation(GO:0060279)
0.5 1.4 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.4 0.8 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
0.3 0.9 GO:0002668 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.3 2.0 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.3 1.5 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.2 2.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.2 0.8 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.2 0.7 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.2 0.7 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.2 2.2 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.2 1.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 4.0 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.1 0.9 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 2.8 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 1.2 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 0.5 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.1 0.3 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.8 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 2.7 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.5 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 0.4 GO:0015722 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.1 0.3 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.3 GO:0050883 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 0.2 GO:0003162 atrioventricular node development(GO:0003162)
0.1 0.2 GO:0060166 olfactory pit development(GO:0060166)
0.1 0.6 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 0.3 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.9 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.2 GO:1901993 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 2.8 GO:0002076 osteoblast development(GO:0002076)
0.1 0.3 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.1 GO:0014016 proximal/distal axis specification(GO:0009946) neuroblast differentiation(GO:0014016)
0.1 0.2 GO:0036269 swimming behavior(GO:0036269)
0.1 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.6 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.1 0.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 1.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.4 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 1.2 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.3 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.5 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.1 0.7 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392) negative regulation of fibrinolysis(GO:0051918)
0.1 0.2 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.5 GO:0050957 equilibrioception(GO:0050957)
0.1 0.2 GO:0060003 copper ion export(GO:0060003) cellular response to lead ion(GO:0071284)
0.0 0.2 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.6 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 2.5 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 1.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.6 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.3 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.7 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.0 1.0 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.2 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.3 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 0.3 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.1 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.0 0.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.9 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.4 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 9.7 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.0 GO:1903797 positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.0 0.1 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.3 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.3 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.4 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.5 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.4 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.1 GO:2000851 positive regulation of glucocorticoid secretion(GO:2000851)
0.0 0.3 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 1.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 1.3 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.4 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.5 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.7 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.2 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.3 GO:0035878 nail development(GO:0035878)
0.0 0.3 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.3 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 1.8 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.4 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:0001777 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.3 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.5 GO:0009886 post-embryonic morphogenesis(GO:0009886)
0.0 0.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.1 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.5 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.2 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.3 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.8 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.1 GO:1902725 regulation of skeletal muscle tissue growth(GO:0048631) negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.3 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.1 GO:1901098 maintenance of Golgi location(GO:0051684) double-strand break repair via classical nonhomologous end joining(GO:0097680) positive regulation of autophagosome maturation(GO:1901098)
0.0 0.0 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) hematopoietic stem cell migration(GO:0035701)
0.0 0.2 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.4 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.3 GO:0098856 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 1.0 GO:0016266 O-glycan processing(GO:0016266)
0.0 1.1 GO:0043525 positive regulation of neuron apoptotic process(GO:0043525)
0.0 0.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0070170 regulation of tooth mineralization(GO:0070170)
0.0 0.7 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.2 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 3.1 GO:0009408 response to heat(GO:0009408)
0.0 0.3 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.1 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0097283 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172) positive regulation of keratinocyte apoptotic process(GO:1902174)
0.0 0.1 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 1.6 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.2 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.2 GO:0009642 response to light intensity(GO:0009642)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.5 2.4 GO:0031523 Myb complex(GO:0031523)
0.3 0.8 GO:0036117 hyaluranon cable(GO:0036117)
0.3 0.8 GO:0005588 collagen type V trimer(GO:0005588)
0.2 1.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.7 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.8 GO:0097149 centralspindlin complex(GO:0097149)
0.1 1.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.3 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 2.0 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.5 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 2.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 3.0 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 4.2 GO:0001533 cornified envelope(GO:0001533)
0.1 0.3 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.3 GO:1990032 parallel fiber(GO:1990032)
0.1 0.9 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.3 GO:0071942 XPC complex(GO:0071942)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 1.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.2 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.0 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.7 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.6 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 2.2 GO:0030673 axolemma(GO:0030673)
0.0 0.5 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.7 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.4 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 3.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.4 GO:0097512 cardiac myofibril(GO:0097512)
0.0 1.5 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 1.0 GO:0036379 myofilament(GO:0036379)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.2 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.7 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 1.6 GO:0016459 myosin complex(GO:0016459)
0.0 0.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.8 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.4 0.7 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.3 5.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.3 0.9 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.3 1.4 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.2 1.9 GO:0034711 inhibin binding(GO:0034711)
0.2 1.2 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.2 0.8 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 1.2 GO:0004969 histamine receptor activity(GO:0004969)
0.1 1.0 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.4 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 2.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.7 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.3 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 1.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.6 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 1.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.5 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.1 0.3 GO:0004773 steryl-sulfatase activity(GO:0004773)
0.1 0.4 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.3 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.5 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 0.3 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 3.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.3 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.6 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 1.7 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.4 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.2 GO:0004618 copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682)
0.0 1.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 1.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 1.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.7 GO:0048185 activin binding(GO:0048185)
0.0 0.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.4 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 1.1 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.7 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.4 GO:0031013 troponin I binding(GO:0031013)
0.0 0.6 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.6 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.9 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 8.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.3 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 2.3 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.7 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.6 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.4 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 4.5 GO:0051015 actin filament binding(GO:0051015)
0.0 0.9 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 1.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.0 GO:0031208 POZ domain binding(GO:0031208)
0.0 1.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 2.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 2.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 2.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 2.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.5 PID AURORA A PATHWAY Aurora A signaling
0.0 1.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.3 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 2.3 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.4 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.5 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.8 NABA COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.0 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 2.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 1.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.9 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.9 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 1.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 2.9 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.5 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 1.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.8 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.6 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 3.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.0 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.8 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.3 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation