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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for SIX1_SIX3_SIX2

Z-value: 0.46

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Transcription factors associated with SIX1_SIX3_SIX2

Gene Symbol Gene ID Gene Info
SIX1
ENSG00000126778.12 SIX1
SIX3
ENSG00000138083.5 SIX3
SIX2
ENSG00000170577.8 SIX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SIX3hg38_v1_chr2_+_44941695_449417080.412.6e-02Click!
SIX2hg38_v1_chr2_-_45009401_450094570.173.6e-01Click!
SIX1hg38_v1_chr14_-_60649449_606494900.106.0e-01Click!

Activity profile of SIX1_SIX3_SIX2 motif

Sorted Z-values of SIX1_SIX3_SIX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SIX1_SIX3_SIX2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr20_-_56525925 0.79 ENST00000243913.8
GCNT7
glucosaminyl (N-acetyl) transferase family member 7
chr1_-_108200849 0.75 ENST00000569674.1
SLC25A24
solute carrier family 25 member 24
chr6_+_84033717 0.65 ENST00000257776.5
MRAP2
melanocortin 2 receptor accessory protein 2
chr11_-_58731968 0.61 ENST00000278400.3
GLYAT
glycine-N-acyltransferase
chr1_-_206946448 0.53 ENST00000356495.5
PIGR
polymeric immunoglobulin receptor
chr13_-_46105009 0.49 ENST00000439329.5
ENST00000674625.1
ENST00000181383.10
CPB2
carboxypeptidase B2
chr14_+_22271921 0.46 ENST00000390464.2
TRAV38-1
T cell receptor alpha variable 38-1
chr14_-_24442241 0.45 ENST00000555355.5
ENST00000553343.5
ENST00000556523.1
ENST00000556249.1
ENST00000538105.6
ENST00000555225.5
SDR39U1
short chain dehydrogenase/reductase family 39U member 1
chr1_+_26410809 0.40 ENST00000254231.4
ENST00000326279.11
LIN28A
lin-28 homolog A
chr11_-_32430811 0.38 ENST00000379079.8
ENST00000530998.5
WT1
WT1 transcription factor
chr11_+_72189528 0.37 ENST00000312293.9
FOLR1
folate receptor alpha
chrX_-_66040107 0.37 ENST00000455586.6
VSIG4
V-set and immunoglobulin domain containing 4
chr6_-_75493773 0.37 ENST00000237172.12
FILIP1
filamin A interacting protein 1
chrX_-_66040057 0.37 ENST00000412866.2
VSIG4
V-set and immunoglobulin domain containing 4
chr9_+_12693327 0.35 ENST00000388918.10
TYRP1
tyrosinase related protein 1
chrX_-_66040072 0.35 ENST00000374737.9
VSIG4
V-set and immunoglobulin domain containing 4
chr3_+_119147375 0.32 ENST00000490594.2
ENSG00000251012.2
novel chromosome 3 open reading frame 30 (C3orf30) and uroplakin 1B (UPK1B)
chr1_+_45500287 0.32 ENST00000401061.9
ENST00000616135.1
MMACHC
metabolism of cobalamin associated C
chr10_-_46046264 0.30 ENST00000581478.5
ENST00000582163.3
MSMB
microseminoprotein beta
chr1_+_241532121 0.29 ENST00000366558.7
KMO
kynurenine 3-monooxygenase
chr7_-_99971845 0.29 ENST00000419575.1
AZGP1
alpha-2-glycoprotein 1, zinc-binding
chr19_+_735026 0.28 ENST00000592155.5
ENST00000590161.2
PALM
paralemmin
chr11_-_58731936 0.28 ENST00000344743.8
GLYAT
glycine-N-acyltransferase
chr2_+_148978361 0.28 ENST00000678720.1
ENST00000678856.1
ENST00000677080.1
KIF5C
kinesin family member 5C
chr1_-_89198868 0.28 ENST00000355754.7
GBP4
guanylate binding protein 4
chr11_-_34511710 0.28 ENST00000620316.4
ENST00000312319.6
ELF5
E74 like ETS transcription factor 5
chr19_+_11346556 0.26 ENST00000587531.5
CCDC159
coiled-coil domain containing 159
chr5_+_126423363 0.26 ENST00000285689.8
GRAMD2B
GRAM domain containing 2B
chr5_+_126423122 0.26 ENST00000515200.5
GRAMD2B
GRAM domain containing 2B
chr3_-_151461011 0.25 ENST00000282466.4
IGSF10
immunoglobulin superfamily member 10
chr1_-_169367746 0.24 ENST00000367811.8
ENST00000472647.5
NME7
NME/NM23 family member 7
chr6_-_24935942 0.24 ENST00000645100.1
ENST00000643898.2
ENST00000613507.4
RIPOR2
RHO family interacting cell polarization regulator 2
chr1_+_182450132 0.24 ENST00000294854.13
RGSL1
regulator of G protein signaling like 1
chr11_+_72080313 0.24 ENST00000307198.11
ENST00000538413.6
ENST00000642648.1
ENST00000289488.7
ENSG00000284922.2
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
leucine rich transmembrane and O-methyltransferase domain containing
chr6_-_46921926 0.23 ENST00000283296.12
ADGRF5
adhesion G protein-coupled receptor F5
chr1_+_14929734 0.23 ENST00000376028.8
ENST00000400798.6
KAZN
kazrin, periplakin interacting protein
chr5_+_126423176 0.23 ENST00000542322.5
ENST00000544396.5
GRAMD2B
GRAM domain containing 2B
chr2_-_206765274 0.22 ENST00000454776.6
ENST00000449792.5
ENST00000374412.8
MDH1B
malate dehydrogenase 1B
chr1_+_13254212 0.22 ENST00000622421.2
PRAMEF5
PRAME family member 5
chr3_-_19934189 0.20 ENST00000295824.14
EFHB
EF-hand domain family member B
chr3_+_149474688 0.20 ENST00000305354.5
ENST00000465758.1
TM4SF4
transmembrane 4 L six family member 4
chr19_+_11346499 0.19 ENST00000458408.6
ENST00000586451.5
ENST00000588592.5
CCDC159
coiled-coil domain containing 159
chr10_+_7703300 0.19 ENST00000358415.9
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr2_+_131527833 0.19 ENST00000295171.10
ENST00000467992.6
ENST00000409856.8
CCDC74A
coiled-coil domain containing 74A
chr1_+_160739239 0.18 ENST00000368043.8
SLAMF7
SLAM family member 7
chr21_+_25639272 0.18 ENST00000400532.5
ENST00000312957.9
JAM2
junctional adhesion molecule 2
chr14_+_50560137 0.18 ENST00000358385.12
ATL1
atlastin GTPase 1
chr1_-_12947580 0.17 ENST00000376189.5
PRAMEF6
PRAME family member 6
chr3_-_11643871 0.17 ENST00000430365.7
VGLL4
vestigial like family member 4
chr22_+_45284941 0.17 ENST00000216211.9
ENST00000396082.2
UPK3A
uroplakin 3A
chr20_+_36236433 0.17 ENST00000397286.7
ENST00000679519.1
ENST00000679667.1
ENST00000680933.1
ENST00000680247.1
ENST00000320849.9
ENST00000680811.1
ENST00000373932.3
AAR2
AAR2 splicing factor
chr12_-_14951106 0.16 ENST00000541644.5
ENST00000545895.5
ARHGDIB
Rho GDP dissociation inhibitor beta
chr6_-_154430495 0.16 ENST00000424998.3
CNKSR3
CNKSR family member 3
chr10_+_112375196 0.16 ENST00000393081.6
ACSL5
acyl-CoA synthetase long chain family member 5
chr8_+_75539862 0.16 ENST00000396423.4
HNF4G
hepatocyte nuclear factor 4 gamma
chr1_+_160739265 0.16 ENST00000368042.7
SLAMF7
SLAM family member 7
chr7_+_77122609 0.16 ENST00000285871.5
CCDC146
coiled-coil domain containing 146
chr2_-_222320124 0.16 ENST00000678139.1
ENSG00000288658.1
novel protein, ortholog of Gm2102 (M. musculus)
chr8_+_75539893 0.15 ENST00000674002.1
HNF4G
hepatocyte nuclear factor 4 gamma
chr11_-_128842467 0.15 ENST00000392664.2
KCNJ1
potassium inwardly rectifying channel subfamily J member 1
chr2_+_218672027 0.15 ENST00000392105.7
ENST00000455724.5
ENST00000295709.8
STK36
serine/threonine kinase 36
chr5_-_35195236 0.15 ENST00000509839.5
PRLR
prolactin receptor
chr6_+_33075952 0.14 ENST00000418931.7
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr10_+_7703340 0.14 ENST00000429820.5
ENST00000379587.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr11_+_55262152 0.13 ENST00000417545.5
TRIM48
tripartite motif containing 48
chr19_+_55947832 0.13 ENST00000291971.7
ENST00000590542.1
NLRP8
NLR family pyrin domain containing 8
chr3_+_69763549 0.13 ENST00000472437.5
MITF
melanocyte inducing transcription factor
chr4_+_88378733 0.13 ENST00000273960.7
ENST00000380265.9
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chrX_-_72875974 0.13 ENST00000595412.5
DMRTC1
DMRT like family C1
chr2_+_233917371 0.13 ENST00000324695.9
ENST00000433712.6
TRPM8
transient receptor potential cation channel subfamily M member 8
chr21_+_25639251 0.13 ENST00000480456.6
JAM2
junctional adhesion molecule 2
chr3_+_44712634 0.13 ENST00000449836.5
ENST00000296091.8
ENST00000436624.7
ENST00000411443.1
ZNF502
zinc finger protein 502
chr2_+_234050732 0.13 ENST00000425558.1
SPP2
secreted phosphoprotein 2
chr1_+_13068677 0.13 ENST00000614839.4
PRAMEF25
PRAME family member 25
chr6_-_149896059 0.13 ENST00000532335.5
RAET1E
retinoic acid early transcript 1E
chr15_+_62561361 0.13 ENST00000561311.5
TLN2
talin 2
chr3_-_42875871 0.12 ENST00000316161.6
ENST00000437102.1
CYP8B1
cytochrome P450 family 8 subfamily B member 1
chr12_+_48727431 0.12 ENST00000548380.6
TEX49
testis expressed 49
chrX_+_115289709 0.12 ENST00000371920.4
ENST00000371921.5
LUZP4
leucine zipper protein 4
chr7_-_44159278 0.12 ENST00000345378.7
GCK
glucokinase
chr9_-_34895722 0.12 ENST00000603640.6
ENST00000603592.1
ENST00000340783.11
FAM205C
family with sequence similarity 205 member C
chr11_+_61752603 0.11 ENST00000278836.10
MYRF
myelin regulatory factor
chr4_+_88378842 0.11 ENST00000264346.12
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr19_-_43082692 0.11 ENST00000406487.6
PSG2
pregnancy specific beta-1-glycoprotein 2
chr19_-_57935353 0.11 ENST00000595569.1
ENST00000599852.1
ENST00000425570.7
ENST00000601593.5
ENST00000396147.6
ZNF418
zinc finger protein 418
chr3_-_46464868 0.11 ENST00000417439.5
ENST00000231751.9
ENST00000431944.1
LTF
lactotransferrin
chr2_-_158380960 0.11 ENST00000409187.5
CCDC148
coiled-coil domain containing 148
chr6_+_31586859 0.11 ENST00000433492.5
LST1
leukocyte specific transcript 1
chr5_+_161685748 0.11 ENST00000523217.5
GABRA6
gamma-aminobutyric acid type A receptor subunit alpha6
chr10_-_101843920 0.11 ENST00000358038.7
KCNIP2
potassium voltage-gated channel interacting protein 2
chr11_+_36296281 0.11 ENST00000530639.6
PRR5L
proline rich 5 like
chr15_+_81134257 0.10 ENST00000286732.5
CFAP161
cilia and flagella associated protein 161
chr10_-_112446932 0.10 ENST00000682195.1
ENST00000683505.1
ENST00000683895.1
ENST00000682839.1
ENST00000682055.1
ZDHHC6
zinc finger DHHC-type palmitoyltransferase 6
chr12_-_89526253 0.10 ENST00000547474.1
POC1B-GALNT4
POC1B-GALNT4 readthrough
chr10_-_101843765 0.10 ENST00000370046.5
KCNIP2
potassium voltage-gated channel interacting protein 2
chr19_-_54063905 0.10 ENST00000645936.1
ENST00000376626.5
ENST00000366170.6
ENST00000425006.3
VSTM1
V-set and transmembrane domain containing 1
chr11_-_126062782 0.10 ENST00000531738.6
CDON
cell adhesion associated, oncogene regulated
chr3_+_23945271 0.10 ENST00000312521.9
NR1D2
nuclear receptor subfamily 1 group D member 2
chr8_+_117135259 0.10 ENST00000519688.5
SLC30A8
solute carrier family 30 member 8
chr16_+_14071303 0.10 ENST00000571589.6
ENST00000574998.5
ENST00000574045.5
MRTFB
myocardin related transcription factor B
chr1_+_40477248 0.10 ENST00000372706.6
ZFP69
ZFP69 zinc finger protein
chrX_+_13569593 0.09 ENST00000361306.6
ENST00000380602.3
EGFL6
EGF like domain multiple 6
chr16_+_75222609 0.09 ENST00000495583.1
CTRB1
chymotrypsinogen B1
chr16_+_21684429 0.09 ENST00000388956.8
OTOA
otoancorin
chr1_-_167935987 0.09 ENST00000367846.8
MPC2
mitochondrial pyruvate carrier 2
chr17_-_74531467 0.09 ENST00000314401.3
ENST00000392621.6
CD300LB
CD300 molecule like family member b
chr21_-_34511243 0.09 ENST00000399284.1
KCNE1
potassium voltage-gated channel subfamily E regulatory subunit 1
chr1_+_12857086 0.09 ENST00000240189.2
PRAMEF2
PRAME family member 2
chr2_-_89297785 0.09 ENST00000465170.1
IGKV1-37
immunoglobulin kappa variable 1-37 (non-functional)
chr15_+_75258599 0.09 ENST00000300576.5
GOLGA6C
golgin A6 family member C
chr11_-_118565992 0.09 ENST00000264020.6
IFT46
intraflagellar transport 46
chr19_+_46297032 0.09 ENST00000377670.9
HIF3A
hypoxia inducible factor 3 subunit alpha
chr1_-_56819365 0.09 ENST00000343433.7
FYB2
FYN binding protein 2
chr1_-_183418364 0.09 ENST00000287713.7
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr17_+_4771878 0.09 ENST00000270560.4
TM4SF5
transmembrane 4 L six family member 5
chr3_+_111998915 0.08 ENST00000478951.6
TAGLN3
transgelin 3
chr1_-_12831410 0.08 ENST00000619922.1
PRAMEF11
PRAME family member 11
chr21_-_42350987 0.08 ENST00000291526.5
TFF2
trefoil factor 2
chr5_+_140175205 0.08 ENST00000644078.1
CYSTM1
cysteine rich transmembrane module containing 1
chr8_-_27605271 0.08 ENST00000522098.1
CLU
clusterin
chr3_+_111999189 0.08 ENST00000455401.6
TAGLN3
transgelin 3
chr14_+_22304051 0.08 ENST00000390466.1
TRAV39
T cell receptor alpha variable 39
chr3_+_111999326 0.08 ENST00000494932.1
TAGLN3
transgelin 3
chr5_-_132737518 0.08 ENST00000403231.6
ENST00000378735.5
ENST00000618515.4
ENST00000378746.8
KIF3A
kinesin family member 3A
chr16_-_1954682 0.08 ENST00000268661.8
RPL3L
ribosomal protein L3 like
chr1_-_12945416 0.08 ENST00000415464.6
PRAMEF6
PRAME family member 6
chr12_+_20695553 0.08 ENST00000545102.1
SLCO1C1
solute carrier organic anion transporter family member 1C1
chr2_-_219170023 0.08 ENST00000409878.8
ENST00000455516.6
ENST00000295738.11
SLC23A3
solute carrier family 23 member 3
chr2_-_55269038 0.08 ENST00000417363.5
ENST00000412530.1
ENST00000366137.6
ENST00000420637.5
MTIF2
mitochondrial translational initiation factor 2
chr11_+_64555956 0.08 ENST00000377581.7
SLC22A11
solute carrier family 22 member 11
chr5_-_161548124 0.08 ENST00000520240.5
ENST00000517901.5
ENST00000353437.10
GABRB2
gamma-aminobutyric acid type A receptor subunit beta2
chr11_-_44950839 0.07 ENST00000395648.7
ENST00000531928.6
TP53I11
tumor protein p53 inducible protein 11
chr1_+_119507203 0.07 ENST00000369413.8
ENST00000528909.1
HSD3B1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
chr8_+_93754844 0.07 ENST00000684064.1
ENST00000498673.5
ENST00000518319.5
TMEM67
transmembrane protein 67
chr12_-_54984667 0.07 ENST00000524668.5
ENST00000533607.1
ENST00000449076.6
TESPA1
thymocyte expressed, positive selection associated 1
chr4_-_155376876 0.07 ENST00000433024.5
ENST00000379248.6
MAP9
microtubule associated protein 9
chr1_+_154321107 0.07 ENST00000484864.1
AQP10
aquaporin 10
chr11_-_49208589 0.07 ENST00000256999.7
FOLH1
folate hydrolase 1
chr9_+_35909481 0.07 ENST00000443779.3
SPAAR
small regulatory polypeptide of amino acid response
chr5_-_146182475 0.07 ENST00000674158.1
ENST00000674191.1
ENST00000274562.13
LARS1
leucyl-tRNA synthetase 1
chr11_-_44950867 0.07 ENST00000528290.5
ENST00000525680.6
ENST00000530035.5
ENST00000527685.5
TP53I11
tumor protein p53 inducible protein 11
chr1_-_207911027 0.07 ENST00000310833.12
CD34
CD34 molecule
chr9_-_72060605 0.07 ENST00000377024.8
ENST00000651200.2
ENST00000652752.1
C9orf57
chromosome 9 open reading frame 57
chr1_-_13155961 0.07 ENST00000624207.1
PRAMEF26
PRAME family member 26
chr3_+_42091316 0.07 ENST00000327628.10
TRAK1
trafficking kinesin protein 1
chr17_+_78187317 0.07 ENST00000409257.9
ENST00000591256.5
ENST00000589256.5
ENST00000588800.5
ENST00000591952.5
ENST00000327898.9
ENST00000586542.5
ENST00000586731.1
AFMID
arylformamidase
chr12_+_133181409 0.07 ENST00000416488.5
ENST00000228289.9
ENST00000541211.6
ENST00000536435.7
ENST00000500625.7
ENST00000539248.6
ENST00000542711.6
ENST00000536899.6
ENST00000542986.6
ENST00000611984.4
ENST00000541975.2
ZNF268
zinc finger protein 268
chr5_-_146182591 0.07 ENST00000510191.5
ENST00000674277.1
ENST00000674447.1
ENST00000674270.1
ENST00000394434.7
ENST00000674290.1
ENST00000674398.1
ENST00000674174.1
LARS1
leucyl-tRNA synthetase 1
chr22_+_36860973 0.07 ENST00000447071.5
ENST00000397147.7
ENST00000248899.11
NCF4
neutrophil cytosolic factor 4
chr12_-_108633864 0.07 ENST00000550948.2
SELPLG
selectin P ligand
chr19_-_3600581 0.07 ENST00000589966.1
TBXA2R
thromboxane A2 receptor
chr1_+_154321076 0.07 ENST00000324978.8
AQP10
aquaporin 10
chr3_+_111998739 0.07 ENST00000393917.6
ENST00000273368.8
TAGLN3
transgelin 3
chr1_+_12791397 0.06 ENST00000332296.7
PRAMEF1
PRAME family member 1
chr6_+_150368997 0.06 ENST00000392255.7
ENST00000500320.7
ENST00000344419.8
IYD
iodotyrosine deiodinase
chr5_-_82278341 0.06 ENST00000510210.5
ENST00000512493.5
ENST00000296674.13
ENST00000507980.1
ENST00000511844.1
ENST00000651545.1
RPS23
ribosomal protein S23
chr16_-_81181312 0.06 ENST00000527937.1
ENST00000531391.5
PKD1L2
polycystin 1 like 2 (gene/pseudogene)
chr2_+_89884740 0.06 ENST00000509129.1
IGKV1D-37
immunoglobulin kappa variable 1D-37 (non-functional)
chr9_-_72060590 0.06 ENST00000652156.1
C9orf57
chromosome 9 open reading frame 57
chr14_+_58244821 0.06 ENST00000216455.9
ENST00000412908.6
ENST00000557508.5
PSMA3
proteasome 20S subunit alpha 3
chr1_+_207104226 0.06 ENST00000367070.8
C4BPA
complement component 4 binding protein alpha
chr10_-_112446891 0.06 ENST00000369404.3
ENST00000369405.7
ENST00000626395.2
ZDHHC6
zinc finger DHHC-type palmitoyltransferase 6
chr2_-_157875820 0.06 ENST00000672582.1
ENST00000673324.1
ENST00000539637.6
ENST00000413751.1
ENST00000424669.6
ENST00000684348.1
ACVR1
activin A receptor type 1
chr20_-_32657362 0.06 ENST00000360785.6
C20orf203
chromosome 20 open reading frame 203
chr6_-_32192845 0.06 ENST00000487761.5
GPSM3
G protein signaling modulator 3
chr2_+_105337515 0.06 ENST00000410049.1
ENST00000258457.7
C2orf49
chromosome 2 open reading frame 49
chr1_-_207911384 0.06 ENST00000356522.4
CD34
CD34 molecule
chr1_-_159076742 0.06 ENST00000368130.9
AIM2
absent in melanoma 2
chr10_+_46375721 0.06 ENST00000616785.1
ENST00000611655.1
ENST00000619162.5
ENSG00000285402.1
ANXA8L1
novel transcript
annexin A8 like 1
chr12_-_89526164 0.06 ENST00000548729.5
POC1B-GALNT4
POC1B-GALNT4 readthrough
chr10_-_112446734 0.06 ENST00000684507.1
ZDHHC6
zinc finger DHHC-type palmitoyltransferase 6
chr9_-_76692181 0.06 ENST00000376717.6
ENST00000223609.10
PRUNE2
prune homolog 2 with BCH domain
chr4_-_121381007 0.06 ENST00000394427.3
QRFPR
pyroglutamylated RFamide peptide receptor
chr11_+_85628573 0.06 ENST00000393375.5
ENST00000358867.11
ENST00000534341.1
ENST00000531274.1
TMEM126B
transmembrane protein 126B
chr4_-_155376935 0.06 ENST00000311277.9
MAP9
microtubule associated protein 9
chr3_+_178536205 0.06 ENST00000420517.6
KCNMB2
potassium calcium-activated channel subfamily M regulatory beta subunit 2
chr6_+_31615984 0.06 ENST00000376049.4
AIF1
allograft inflammatory factor 1
chr2_-_89213917 0.06 ENST00000498435.1
IGKV1-27
immunoglobulin kappa variable 1-27
chr1_-_230745574 0.06 ENST00000681269.1
AGT
angiotensinogen
chr12_-_6689450 0.06 ENST00000355772.8
ENST00000417772.7
ENST00000319770.7
ENST00000396801.7
ZNF384
zinc finger protein 384
chr11_-_10568571 0.06 ENST00000529598.1
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr1_+_160151597 0.06 ENST00000368081.9
ATP1A4
ATPase Na+/K+ transporting subunit alpha 4
chr10_-_101843777 0.06 ENST00000356640.7
KCNIP2
potassium voltage-gated channel interacting protein 2
chr19_-_10928512 0.06 ENST00000588347.5
YIPF2
Yip1 domain family member 2
chr22_+_20080211 0.05 ENST00000383024.6
ENST00000351989.8
DGCR8
DGCR8 microprocessor complex subunit
chr1_+_27725945 0.05 ENST00000373954.11
ENST00000419687.6
FAM76A
family with sequence similarity 76 member A
chr4_-_155376797 0.05 ENST00000650955.1
ENST00000515654.5
MAP9
microtubule associated protein 9
chr9_+_35910076 0.05 ENST00000636776.1
SPAAR
small regulatory polypeptide of amino acid response
chr19_-_38229714 0.05 ENST00000416611.5
DPF1
double PHD fingers 1
chr11_+_64555924 0.05 ENST00000301891.9
SLC22A11
solute carrier family 22 member 11
chr3_-_142000353 0.05 ENST00000499676.5
TFDP2
transcription factor Dp-2
chr5_+_112976757 0.05 ENST00000389063.3
DCP2
decapping mRNA 2
chr6_-_24358036 0.05 ENST00000378454.8
DCDC2
doublecortin domain containing 2
chrX_+_102651366 0.05 ENST00000415986.5
ENST00000444152.5
ENST00000361600.9
GPRASP1
G protein-coupled receptor associated sorting protein 1
chr19_+_55605639 0.05 ENST00000568956.2
ZNF865
zinc finger protein 865
chr16_+_84768246 0.05 ENST00000569925.1
ENST00000567526.1
USP10
ubiquitin specific peptidase 10
chr19_+_57584131 0.05 ENST00000536878.6
ENST00000597219.1
ENST00000598689.1
ENST00000597850.2
ZIK1
zinc finger protein interacting with K protein 1
chr19_+_7497544 0.05 ENST00000361664.7
TEX45
testis expressed 45
chr11_+_64555684 0.05 ENST00000377585.7
SLC22A11
solute carrier family 22 member 11
chr9_-_122159742 0.05 ENST00000373768.4
NDUFA8
NADH:ubiquinone oxidoreductase subunit A8

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.1 0.5 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.4 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.1 0.4 GO:0072302 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.1 0.4 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.3 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.3 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.8 GO:0015866 ADP transport(GO:0015866)
0.0 1.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:2001107 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.0 0.1 GO:0035759 mesangial cell-matrix adhesion(GO:0035759) positive regulation of granulocyte colony-stimulating factor production(GO:0071657) metanephric mesangial cell differentiation(GO:0072209) metanephric glomerular mesangial cell differentiation(GO:0072254) positive regulation of macrophage colony-stimulating factor production(GO:1901258)
0.0 0.3 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.0 0.3 GO:0001705 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.0 0.3 GO:0015840 urea transport(GO:0015840)
0.0 0.2 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.1 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.1 GO:0042710 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229) positive regulation of chondrocyte proliferation(GO:1902732)
0.0 0.2 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.4 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.3 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.1 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.1 GO:0061445 endocardial cell fate commitment(GO:0060957) endocardial cushion cell fate commitment(GO:0061445)
0.0 0.2 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.1 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.2 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.2 GO:0043129 surfactant homeostasis(GO:0043129) positive regulation of phospholipid biosynthetic process(GO:0071073)
0.0 0.1 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.1 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:0090301 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0 0.0 GO:1903937 response to acrylamide(GO:1903937)
0.0 0.0 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.2 GO:0042424 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 0.1 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
0.0 0.0 GO:1902996 regulation of neurofibrillary tangle assembly(GO:1902996)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.0 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.7 GO:0097009 energy homeostasis(GO:0097009)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1905103 integral component of lysosomal membrane(GO:1905103)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.2 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.1 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.3 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.0 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.0 GO:0008537 proteasome activator complex(GO:0008537)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.1 0.9 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.1 0.4 GO:0061714 folic acid receptor activity(GO:0061714)
0.1 0.5 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 0.3 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.1 0.4 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.1 0.8 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.2 GO:0015265 urea channel activity(GO:0015265)
0.0 0.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.1 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.1 GO:1904493 Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
0.0 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0043199 sulfate binding(GO:0043199)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins