Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
SIX4 Links Ensembl NCBI GeneCards UniProt	ENSG00000100625.9	SIX4

Gene	Promoter	Pearson corr. coef.	P-value	Plot
SIX4	hg38_v1_chr14_-_60724300_60724362	0.33	7.5e-02	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chrY_+_20575792 Show fit	0.97	ENST00000382772.3	EIF1AY Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 1A Y-linked
chrY_+_20575716 Show fit	0.84	ENST00000361365.7	EIF1AY Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 1A Y-linked
chr16_-_53052849 Show fit	0.65	ENST00000619363.2	ENSG00000277639.2 Links Ensembl NCBI GeneCards UniProt Show fit	novel protein
chr12_-_10130241 Show fit	0.44	ENST00000353231.9 ENST00000525605.1	CLEC7A Links Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain containing 7A
chr8_+_143716318 Show fit	0.43	ENST00000338033.9 ENST00000395107.8 ENST00000395108.2	MAPK15 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase 15
chr3_+_119147375 Show fit	0.41	ENST00000490594.2	ENSG00000251012.2 Links Ensembl NCBI GeneCards UniProt Show fit	novel chromosome 3 open reading frame 30 (C3orf30) and uroplakin 1B (UPK1B)
chr12_-_10130143 Show fit	0.37	ENST00000298523.9 ENST00000396484.6 ENST00000310002.4 ENST00000304084.13	CLEC7A Links Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain containing 7A
chr6_-_75363003 Show fit	0.28	ENST00000370020.1	FILIP1 Links Ensembl NCBI GeneCards UniProt Show fit	filamin A interacting protein 1
chr1_-_183590876 Show fit	0.26	ENST00000367536.5	NCF2 Links Ensembl NCBI GeneCards UniProt Show fit	neutrophil cytosolic factor 2
chr8_+_94895763 Show fit	0.24	ENST00000523378.5	NDUFAF6 Links Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase complex assembly factor 6
chr12_-_10130082 Show fit	0.22	ENST00000533022.5	CLEC7A Links Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain containing 7A
chrX_+_9560465 Show fit	0.22	ENST00000647060.1	TBL1X Links Ensembl NCBI GeneCards UniProt Show fit	transducin beta like 1 X-linked
chr11_-_130314686 Show fit	0.21	ENST00000525842.5	ZBTB44 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 44
chr6_+_52186373 Show fit	0.19	ENST00000648244.1	IL17A Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 17A
chr14_-_91946989 Show fit	0.17	ENST00000556154.5	FBLN5 Links Ensembl NCBI GeneCards UniProt Show fit	fibulin 5
chr15_+_40953463 Show fit	0.17	ENST00000617768.5	CHAC1 Links Ensembl NCBI GeneCards UniProt Show fit	ChaC glutathione specific gamma-glutamylcyclotransferase 1
chr11_-_130314575 Show fit	0.17	ENST00000397753.5	ZBTB44 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 44
chr12_+_4720395 Show fit	0.17	ENST00000252318.7	GALNT8 Links Ensembl NCBI GeneCards UniProt Show fit	polypeptide N-acetylgalactosaminyltransferase 8
chr13_-_77918788 Show fit	0.17	ENST00000626030.1	EDNRB Links Ensembl NCBI GeneCards UniProt Show fit	endothelin receptor type B
chr14_-_67515153 Show fit	0.16	ENST00000555994.6	TMEM229B Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 229B
chr17_-_74531467 Show fit	0.15	ENST00000314401.3 ENST00000392621.6	CD300LB Links Ensembl NCBI GeneCards UniProt Show fit	CD300 molecule like family member b
chr14_-_106349792 Show fit	0.15	ENST00000438142.3	IGHV4-31 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 4-31
chr8_+_94895837 Show fit	0.14	ENST00000519136.5	NDUFAF6 Links Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase complex assembly factor 6
chr12_-_4379712 Show fit	0.14	ENST00000237837.2	FGF23 Links Ensembl NCBI GeneCards UniProt Show fit	fibroblast growth factor 23
chr19_+_859654 Show fit	0.14	ENST00000592860.2 ENST00000327726.11	CFD Links Ensembl NCBI GeneCards UniProt Show fit	complement factor D
chr22_-_30564889 Show fit	0.14	ENST00000401975.5 ENST00000428682.5 ENST00000423299.5	GAL3ST1 Links Ensembl NCBI GeneCards UniProt Show fit	galactose-3-O-sulfotransferase 1
chr16_+_590200 Show fit	0.14	ENST00000563109.1	RAB40C Links Ensembl NCBI GeneCards UniProt Show fit	RAB40C, member RAS oncogene family
chrX_+_54440396 Show fit	0.13	ENST00000375151.5	TSR2 Links Ensembl NCBI GeneCards UniProt Show fit	TSR2 ribosome maturation factor
chr6_-_31736504 Show fit	0.13	ENST00000616760.1 ENST00000375784.7 ENST00000375779.6	CLIC1 Links Ensembl NCBI GeneCards UniProt Show fit	chloride intracellular channel 1
chr1_+_160127672 Show fit	0.13	ENST00000447527.1	ATP1A2 Links Ensembl NCBI GeneCards UniProt Show fit	ATPase Na+/K+ transporting subunit alpha 2
chr10_+_86654541 Show fit	0.13	ENST00000241891.10 ENST00000372071.6	OPN4 Links Ensembl NCBI GeneCards UniProt Show fit	opsin 4
chr3_+_32685128 Show fit	0.13	ENST00000331889.10 ENST00000328834.9	CNOT10 Links Ensembl NCBI GeneCards UniProt Show fit	CCR4-NOT transcription complex subunit 10
chr7_+_69599588 Show fit	0.12	ENST00000403018.3	AUTS2 Links Ensembl NCBI GeneCards UniProt Show fit	activator of transcription and developmental regulator AUTS2
chr1_-_37947010 Show fit	0.12	ENST00000458109.6 ENST00000373024.8 ENST00000373023.6	INPP5B Links Ensembl NCBI GeneCards UniProt Show fit	inositol polyphosphate-5-phosphatase B
chr11_-_96343170 Show fit	0.12	ENST00000524717.6	MAML2 Links Ensembl NCBI GeneCards UniProt Show fit	mastermind like transcriptional coactivator 2
chr11_+_31816266 Show fit	0.12	ENST00000644607.1 ENST00000646221.1 ENST00000643671.1 ENST00000643931.1 ENST00000642614.1 ENST00000642818.1 ENST00000645848.1 ENST00000506388.2 ENST00000645824.1 ENST00000532942.5	PAUPAR Links Ensembl NCBI GeneCards UniProt Show fit ENSG00000285283.1 Links Ensembl NCBI GeneCards UniProt Show fit	PAX6 upstream antisense RNA novel protein
chr9_-_34895722 Show fit	0.12	ENST00000603640.6 ENST00000603592.1 ENST00000340783.11	FAM205C Links Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 205 member C
chr1_+_231338242 Show fit	0.11	ENST00000008440.9 ENST00000295050.12	SPRTN Links Ensembl NCBI GeneCards UniProt Show fit	SprT-like N-terminal domain
chr8_+_131904071 Show fit	0.11	ENST00000254624.10 ENST00000522709.5	EFR3A Links Ensembl NCBI GeneCards UniProt Show fit	EFR3 homolog A
chr22_-_38872206 Show fit	0.11	ENST00000407418.8 ENST00000216083.6	CBX6 Links Ensembl NCBI GeneCards UniProt Show fit	chromobox 6
chr20_-_54070520 Show fit	0.11	ENST00000371435.6 ENST00000395961.7	BCAS1 Links Ensembl NCBI GeneCards UniProt Show fit	brain enriched myelin associated protein 1
chr19_-_474880 Show fit	0.11	ENST00000382696.7 ENST00000315489.5	ODF3L2 Links Ensembl NCBI GeneCards UniProt Show fit	outer dense fiber of sperm tails 3 like 2
chr3_-_168095885 Show fit	0.11	ENST00000470487.6	GOLIM4 Links Ensembl NCBI GeneCards UniProt Show fit	golgi integral membrane protein 4
chr1_+_161153968 Show fit	0.10	ENST00000368003.6	UFC1 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin-fold modifier conjugating enzyme 1
chr11_+_64241053 Show fit	0.10	ENST00000309366.9 ENST00000449942.6 ENST00000652762.2	FKBP2 Links Ensembl NCBI GeneCards UniProt Show fit ENSG00000286264.2 Links Ensembl NCBI GeneCards UniProt Show fit	FKBP prolyl isomerase 2 novel protein
chrX_+_136305988 Show fit	0.10	ENST00000394141.1	ADGRG4 Links Ensembl NCBI GeneCards UniProt Show fit	adhesion G protein-coupled receptor G4
chr1_+_26410809 Show fit	0.10	ENST00000254231.4 ENST00000326279.11	LIN28A Links Ensembl NCBI GeneCards UniProt Show fit	lin-28 homolog A
chr1_+_156642148 Show fit	0.10	ENST00000361588.5	BCAN Links Ensembl NCBI GeneCards UniProt Show fit	brevican
chr11_+_119067774 Show fit	0.10	ENST00000621676.5 ENST00000614944.4	VPS11 Links Ensembl NCBI GeneCards UniProt Show fit	VPS11 core subunit of CORVET and HOPS complexes
chr8_+_94895813 Show fit	0.09	ENST00000396113.5	NDUFAF6 Links Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase complex assembly factor 6
chr5_-_79069668 Show fit	0.09	ENST00000255189.8	DMGDH Links Ensembl NCBI GeneCards UniProt Show fit	dimethylglycine dehydrogenase
chr1_+_156642108 Show fit	0.09	ENST00000457777.6 ENST00000329117.10 ENST00000424639.5	BCAN Links Ensembl NCBI GeneCards UniProt Show fit	brevican
chr1_-_16352420 Show fit	0.09	ENST00000375592.8	FBXO42 Links Ensembl NCBI GeneCards UniProt Show fit	F-box protein 42
chr17_+_7561899 Show fit	0.09	ENST00000321337.12	SENP3 Links Ensembl NCBI GeneCards UniProt Show fit	SUMO specific peptidase 3
chr10_+_7818497 Show fit	0.08	ENST00000344293.6	TAF3 Links Ensembl NCBI GeneCards UniProt Show fit	TATA-box binding protein associated factor 3
chr1_-_113871665 Show fit	0.08	ENST00000528414.5 ENST00000460620.5 ENST00000359785.10 ENST00000420377.6 ENST00000525799.1 ENST00000538253.5	PTPN22 Links Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase non-receptor type 22
chr3_-_168095344 Show fit	0.07	ENST00000309027.4	GOLIM4 Links Ensembl NCBI GeneCards UniProt Show fit	golgi integral membrane protein 4
chr14_-_106235582 Show fit	0.07	ENST00000390607.2	IGHV3-21 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-21
chr17_-_63446260 Show fit	0.07	ENST00000448884.6 ENST00000582297.5 ENST00000360793.8 ENST00000582034.5 ENST00000578072.1	CYB561 Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome b561
chr7_+_97732046 Show fit	0.07	ENST00000350485.8 ENST00000346867.4 ENST00000319273.10	TAC1 Links Ensembl NCBI GeneCards UniProt Show fit	tachykinin precursor 1
chr5_-_1294989 Show fit	0.07	ENST00000334602.10 ENST00000310581.10	TERT Links Ensembl NCBI GeneCards UniProt Show fit	telomerase reverse transcriptase
chr1_-_247172002 Show fit	0.07	ENST00000491356.5 ENST00000472531.5 ENST00000340684.10 ENST00000543802.3	ZNF124 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 124
chrX_+_30235894 Show fit	0.06	ENST00000620842.1	MAGEB3 Links Ensembl NCBI GeneCards UniProt Show fit	MAGE family member B3
chr7_-_14841267 Show fit	0.06	ENST00000406247.7 ENST00000399322.7	DGKB Links Ensembl NCBI GeneCards UniProt Show fit	diacylglycerol kinase beta
chr19_+_34926892 Show fit	0.06	ENST00000303586.11 ENST00000601142.2 ENST00000439785.5 ENST00000601540.5 ENST00000601957.5	ZNF30 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 30
chr1_+_116373233 Show fit	0.06	ENST00000295598.10	ATP1A1 Links Ensembl NCBI GeneCards UniProt Show fit	ATPase Na+/K+ transporting subunit alpha 1
chr3_-_87276577 Show fit	0.06	ENST00000344265.8 ENST00000350375.7	POU1F1 Links Ensembl NCBI GeneCards UniProt Show fit	POU class 1 homeobox 1
chr3_-_122993232 Show fit	0.06	ENST00000650207.1 ENST00000616742.4 ENST00000393583.6	SEMA5B Links Ensembl NCBI GeneCards UniProt Show fit	semaphorin 5B
chr3_-_87276462 Show fit	0.06	ENST00000561167.5 ENST00000560656.1	POU1F1 Links Ensembl NCBI GeneCards UniProt Show fit	POU class 1 homeobox 1
chr11_+_7251886 Show fit	0.04	ENST00000318881.11	SYT9 Links Ensembl NCBI GeneCards UniProt Show fit	synaptotagmin 9
chr1_-_231337830 Show fit	0.04	ENST00000366645.1	EXOC8 Links Ensembl NCBI GeneCards UniProt Show fit	exocyst complex component 8
chr12_-_57846686 Show fit	0.04	ENST00000548823.1 ENST00000398073.7	CTDSP2 Links Ensembl NCBI GeneCards UniProt Show fit	CTD small phosphatase 2
chr19_+_19063986 Show fit	0.04	ENST00000318596.8	SLC25A42 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 25 member 42
chr17_+_50561010 Show fit	0.04	ENST00000360761.8 ENST00000354983.8 ENST00000352832.9	CACNA1G Links Ensembl NCBI GeneCards UniProt Show fit	calcium voltage-gated channel subunit alpha1 G
chr1_-_154961720 Show fit	0.04	ENST00000368457.3	PYGO2 Links Ensembl NCBI GeneCards UniProt Show fit	pygopus family PHD finger 2
chr11_-_5343524 Show fit	0.04	ENST00000300773.3	OR51B5 Links Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 51 subfamily B member 5
chr19_+_35329161 Show fit	0.04	ENST00000341773.10 ENST00000600131.5 ENST00000595780.5 ENST00000597916.5 ENST00000593867.5 ENST00000600424.5 ENST00000599811.5 ENST00000536635.6 ENST00000085219.10 ENST00000544992.6 ENST00000419549.6	CD22 Links Ensembl NCBI GeneCards UniProt Show fit	CD22 molecule
chr17_-_59707404 Show fit	0.03	ENST00000393038.3	PTRH2 Links Ensembl NCBI GeneCards UniProt Show fit	peptidyl-tRNA hydrolase 2
chr13_-_48001265 Show fit	0.03	ENST00000646932.1 ENST00000433022.1 ENST00000470760.2 ENST00000644338.1 ENST00000646602.1	SUCLA2 Links Ensembl NCBI GeneCards UniProt Show fit	succinate-CoA ligase ADP-forming subunit beta
chrX_+_109537118 Show fit	0.03	ENST00000372103.1	NXT2 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear transport factor 2 like export factor 2
chr19_-_46625037 Show fit	0.03	ENST00000596260.1 ENST00000594275.1 ENST00000597185.1 ENST00000598865.5 ENST00000291294.7	PTGIR Links Ensembl NCBI GeneCards UniProt Show fit	prostaglandin I2 receptor
chr13_-_48001305 Show fit	0.03	ENST00000643023.1	SUCLA2 Links Ensembl NCBI GeneCards UniProt Show fit	succinate-CoA ligase ADP-forming subunit beta
chr19_+_29923644 Show fit	0.02	ENST00000360605.8 ENST00000570564.5 ENST00000574233.5 ENST00000585655.1	URI1 Links Ensembl NCBI GeneCards UniProt Show fit	URI1 prefoldin like chaperone
chrX_-_120629936 Show fit	0.02	ENST00000371313.2 ENST00000304661.6	C1GALT1C1 Links Ensembl NCBI GeneCards UniProt Show fit	C1GALT1 specific chaperone 1
chr3_-_49120785 Show fit	0.02	ENST00000417901.5 ENST00000306026.5 ENST00000434032.6	USP19 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 19
chr11_-_14359118 Show fit	0.02	ENST00000256196.9	RRAS2 Links Ensembl NCBI GeneCards UniProt Show fit	RAS related 2
chr20_+_59300402 Show fit	0.02	ENST00000311585.11 ENST00000371028.6	EDN3 Links Ensembl NCBI GeneCards UniProt Show fit	endothelin 3
chr3_-_184249520 Show fit	0.01	ENST00000455059.5 ENST00000445626.6	ALG3 Links Ensembl NCBI GeneCards UniProt Show fit	ALG3 alpha-1,3- mannosyltransferase
chr20_+_59300547 Show fit	0.01	ENST00000644821.1	EDN3 Links Ensembl NCBI GeneCards UniProt Show fit	endothelin 3
chr3_-_93973833 Show fit	0.01	ENST00000348974.5 ENST00000647936.1 ENST00000394236.9 ENST00000407433.6	PROS1 Links Ensembl NCBI GeneCards UniProt Show fit	protein S
chr5_+_79069754 Show fit	0.01	ENST00000518666.5 ENST00000521567.1 ENST00000255192.8	BHMT2 Links Ensembl NCBI GeneCards UniProt Show fit	betaine--homocysteine S-methyltransferase 2
chr17_-_41528293 Show fit	0.00	ENST00000455635.1 ENST00000361566.7	KRT19 Links Ensembl NCBI GeneCards UniProt Show fit	keratin 19
chr2_-_74482914 Show fit	0.00	ENST00000290418.4 ENST00000393965.8	CCDC142 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 142
chr7_-_113919000 Show fit	0.00	ENST00000284601.4	PPP1R3A Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory subunit 3A
chr1_+_116754422 Show fit	0.00	ENST00000369478.4 ENST00000369477.1	CD2 Links Ensembl NCBI GeneCards UniProt Show fit	CD2 molecule
chr14_-_94517844 Show fit	0.00	ENST00000341228.2	SERPINA12 Links Ensembl NCBI GeneCards UniProt Show fit	serpin family A member 12

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	GO:1900920	regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.0	1.0	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.0	0.2	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	0.1	GO:0042369	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) vitamin D catabolic process(GO:0042369) response to sodium phosphate(GO:1904383)
0.0	0.1	GO:0006579	amino-acid betaine catabolic process(GO:0006579)
0.0	0.1	GO:0060133	somatotropin secreting cell development(GO:0060133)
0.0	0.1	GO:0010587	miRNA catabolic process(GO:0010587)
0.0	0.4	GO:1904355	positive regulation of telomere capping(GO:1904355)
0.0	0.1	GO:0006781	succinyl-CoA pathway(GO:0006781)
0.0	0.1	GO:0046878	positive regulation of saliva secretion(GO:0046878)
0.0	0.1	GO:1902523	negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0	0.1	GO:0019375	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0	0.1	GO:1990564	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0	0.2	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.1	GO:2000620	innate vocalization behavior(GO:0098582) positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0	0.1	GO:1904751	positive regulation of protein localization to nucleolus(GO:1904751)
0.0	0.1	GO:0016926	protein desumoylation(GO:0016926)
0.0	0.0	GO:0001927	exocyst assembly(GO:0001927)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.3	GO:0032010	phagolysosome(GO:0032010)
0.0	0.1	GO:0000333	telomerase catalytic core complex(GO:0000333)
0.0	0.2	GO:0071953	elastic fiber(GO:0071953)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.2	GO:0003839	gamma-glutamylcyclotransferase activity(GO:0003839)
0.0	1.0	GO:0008329	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.1	GO:0005502	11-cis retinal binding(GO:0005502)
0.0	1.8	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.1	GO:0046997	oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.0	0.3	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.1	GO:0022865	transmembrane electron transfer carrier(GO:0022865)
0.0	0.1	GO:0050694	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0	0.2	GO:1990239	steroid hormone binding(GO:1990239)
0.0	0.1	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.0	GO:0086059	voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.0	0.4	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.1	GO:0016929	SUMO-specific protease activity(GO:0016929)