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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for SIX6

Z-value: 0.48

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Transcription factors associated with SIX6

Gene Symbol Gene ID Gene Info
SIX6
ENSG00000184302.7 SIX6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SIX6hg38_v1_chr14_+_60509138_605091630.291.2e-01Click!

Activity profile of SIX6 motif

Sorted Z-values of SIX6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SIX6

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr15_-_79971164 0.82 ENST00000335661.6
ENST00000267953.4
ENST00000677151.1
BCL2A1
BCL2 related protein A1
chr12_-_121039204 0.74 ENST00000620239.5
OASL
2'-5'-oligoadenylate synthetase like
chr12_-_121039236 0.70 ENST00000257570.9
OASL
2'-5'-oligoadenylate synthetase like
chr12_-_121039156 0.69 ENST00000339275.10
OASL
2'-5'-oligoadenylate synthetase like
chr1_+_13585453 0.65 ENST00000487038.5
ENST00000475043.5
PDPN
podoplanin
chr12_-_121038967 0.45 ENST00000680620.1
ENST00000679655.1
ENST00000543677.2
OASL
2'-5'-oligoadenylate synthetase like
chr2_-_88128049 0.45 ENST00000393750.3
ENST00000295834.8
FABP1
fatty acid binding protein 1
chr9_-_97944832 0.40 ENST00000259456.7
HEMGN
hemogen
chr22_-_19150292 0.39 ENST00000086933.3
GSC2
goosecoid homeobox 2
chr12_-_27970047 0.39 ENST00000395868.7
PTHLH
parathyroid hormone like hormone
chr12_-_27970273 0.39 ENST00000542963.1
ENST00000535992.5
PTHLH
parathyroid hormone like hormone
chr8_+_2045037 0.36 ENST00000262113.9
MYOM2
myomesin 2
chr18_+_44680093 0.34 ENST00000426838.8
ENST00000677068.1
SETBP1
SET binding protein 1
chr8_+_2045058 0.34 ENST00000523438.1
MYOM2
myomesin 2
chr6_-_26285526 0.31 ENST00000377727.2
H4C8
H4 clustered histone 8
chr6_-_26197272 0.31 ENST00000356476.3
H3C4
H3 clustered histone 4
chr16_+_21678514 0.30 ENST00000286149.8
ENST00000388958.8
OTOA
otoancorin
chr10_+_89301932 0.29 ENST00000371826.4
ENST00000679755.1
IFIT2
interferon induced protein with tetratricopeptide repeats 2
chr1_-_35769928 0.28 ENST00000373220.7
ENST00000520551.1
CLSPN
claspin
chr9_-_21141832 0.28 ENST00000380229.4
IFNW1
interferon omega 1
chr13_+_33818063 0.28 ENST00000434425.5
RFC3
replication factor C subunit 3
chr12_-_10826358 0.27 ENST00000240619.2
TAS2R10
taste 2 receptor member 10
chr17_+_64449037 0.26 ENST00000615220.4
ENST00000619286.5
ENST00000612535.4
ENST00000616498.4
MILR1
mast cell immunoglobulin like receptor 1
chr6_-_107824294 0.26 ENST00000369020.8
ENST00000369022.6
SCML4
Scm polycomb group protein like 4
chr12_-_14696571 0.24 ENST00000261170.5
GUCY2C
guanylate cyclase 2C
chr6_+_26204552 0.24 ENST00000615164.2
H4C5
H4 clustered histone 5
chr3_+_155083523 0.24 ENST00000680057.1
MME
membrane metalloendopeptidase
chr21_-_18403754 0.23 ENST00000284885.8
TMPRSS15
transmembrane serine protease 15
chr8_-_100145802 0.22 ENST00000428847.3
FBXO43
F-box protein 43
chr14_+_20469399 0.22 ENST00000361505.10
ENST00000553591.1
PNP
purine nucleoside phosphorylase
chr1_-_225567270 0.22 ENST00000497899.6
ENAH
ENAH actin regulator
chr14_+_21042352 0.22 ENST00000298690.5
RNASE7
ribonuclease A family member 7
chr15_+_58138368 0.21 ENST00000219919.9
ENST00000536493.1
AQP9
aquaporin 9
chr22_+_24270776 0.21 ENST00000437398.5
ENST00000421374.5
ENST00000314328.14
ENST00000651059.1
ENST00000541492.1
SPECC1L
sperm antigen with calponin homology and coiled-coil domains 1 like
chr6_+_29170907 0.21 ENST00000641417.1
OR2J2
olfactory receptor family 2 subfamily J member 2
chrY_+_14056226 0.20 ENST00000250823.5
VCY1B
variable charge Y-linked 1B
chr6_+_146027662 0.20 ENST00000492807.6
ENST00000361719.6
GRM1
glutamate metabotropic receptor 1
chr7_-_48029102 0.20 ENST00000297325.9
ENST00000412142.5
ENST00000395572.6
SUN3
Sad1 and UNC84 domain containing 3
chr1_+_86468902 0.19 ENST00000394711.2
CLCA1
chloride channel accessory 1
chr2_+_88885397 0.19 ENST00000390243.2
IGKV4-1
immunoglobulin kappa variable 4-1
chr1_+_197413827 0.18 ENST00000367397.1
ENST00000681519.1
CRB1
crumbs cell polarity complex component 1
chr4_+_77605807 0.18 ENST00000682537.1
CXCL13
C-X-C motif chemokine ligand 13
chr1_-_35769958 0.18 ENST00000251195.9
ENST00000318121.8
CLSPN
claspin
chr3_+_8501807 0.18 ENST00000426878.2
ENST00000397386.7
ENST00000415597.5
ENST00000157600.8
LMCD1
LIM and cysteine rich domains 1
chr13_-_19505940 0.18 ENST00000400103.6
TPTE2
transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
chr1_+_160739286 0.17 ENST00000359331.8
ENST00000495334.1
SLAMF7
SLAM family member 7
chr19_-_35563653 0.17 ENST00000262623.4
ATP4A
ATPase H+/K+ transporting subunit alpha
chr11_-_102625332 0.16 ENST00000260228.3
MMP20
matrix metallopeptidase 20
chrY_-_13986473 0.16 ENST00000250825.5
VCY
variable charge Y-linked
chr4_-_122456725 0.16 ENST00000226730.5
IL2
interleukin 2
chr18_+_52752032 0.15 ENST00000412726.5
ENST00000578080.1
ENST00000582875.1
DCC
DCC netrin 1 receptor
chr6_-_152637351 0.15 ENST00000367255.10
SYNE1
spectrin repeat containing nuclear envelope protein 1
chr19_-_14848922 0.15 ENST00000641129.1
OR7A10
olfactory receptor family 7 subfamily A member 10
chrX_+_7843088 0.15 ENST00000341408.5
VCX
variable charge X-linked
chr1_-_161045961 0.14 ENST00000368021.7
USF1
upstream transcription factor 1
chr1_-_161223559 0.14 ENST00000469730.2
ENST00000463273.5
ENST00000464492.5
ENST00000367990.7
ENST00000470459.6
ENST00000463812.1
ENST00000468465.5
APOA2
apolipoprotein A2
chrX_-_33211540 0.14 ENST00000357033.9
DMD
dystrophin
chr1_+_160739265 0.14 ENST00000368042.7
SLAMF7
SLAM family member 7
chr12_-_21334858 0.13 ENST00000445053.1
ENST00000458504.5
ENST00000422327.5
ENST00000683939.1
SLCO1A2
solute carrier organic anion transporter family member 1A2
chr22_-_17221841 0.13 ENST00000449907.7
ENST00000441548.1
ENST00000399839.5
ADA2
adenosine deaminase 2
chr1_-_13347134 0.13 ENST00000334600.7
PRAMEF14
PRAME family member 14
chr4_-_69961007 0.12 ENST00000353151.3
CSN2
casein beta
chr5_+_40909490 0.12 ENST00000313164.10
C7
complement C7
chr2_+_85595684 0.12 ENST00000441634.5
ENST00000306368.9
ENST00000414390.5
ENST00000456023.1
RNF181
ring finger protein 181
chr1_-_182400660 0.11 ENST00000367565.2
TEDDM1
transmembrane epididymal protein 1
chrX_+_8465426 0.11 ENST00000381029.4
VCX3B
variable charge X-linked 3B
chr22_+_17563433 0.11 ENST00000399813.1
SLC25A18
solute carrier family 25 member 18
chr5_+_161850597 0.10 ENST00000634335.1
ENST00000635880.1
GABRA1
gamma-aminobutyric acid type A receptor subunit alpha1
chr6_+_47781982 0.10 ENST00000489301.6
ENST00000638973.1
ENST00000371211.6
ENST00000393699.2
OPN5
opsin 5
chr6_-_26043704 0.10 ENST00000615966.2
H2BC3
H2B clustered histone 3
chr1_+_62597510 0.10 ENST00000371129.4
ANGPTL3
angiopoietin like 3
chr22_+_17563485 0.10 ENST00000327451.11
SLC25A18
solute carrier family 25 member 18
chr5_+_75512058 0.10 ENST00000514296.5
POLK
DNA polymerase kappa
chr2_-_133568393 0.09 ENST00000317721.10
ENST00000405974.7
ENST00000409261.6
ENST00000409213.5
NCKAP5
NCK associated protein 5
chr3_-_151461011 0.09 ENST00000282466.4
IGSF10
immunoglobulin superfamily member 10
chr3_-_196515315 0.09 ENST00000397537.3
SMCO1
single-pass membrane protein with coiled-coil domains 1
chr14_-_69574845 0.09 ENST00000599174.3
CCDC177
coiled-coil domain containing 177
chr6_+_127577168 0.09 ENST00000329722.8
C6orf58
chromosome 6 open reading frame 58
chr1_+_160739239 0.09 ENST00000368043.8
SLAMF7
SLAM family member 7
chr2_+_201132928 0.08 ENST00000462763.5
CFLAR
CASP8 and FADD like apoptosis regulator
chr19_-_15125659 0.08 ENST00000533747.1
ENST00000598709.1
ENST00000534378.5
ILVBL
ilvB acetolactate synthase like
chr14_-_106627685 0.08 ENST00000390629.3
IGHV4-59
immunoglobulin heavy variable 4-59
chr18_-_36798482 0.07 ENST00000590258.2
TPGS2
tubulin polyglutamylase complex subunit 2
chr4_-_154590735 0.07 ENST00000403106.8
ENST00000622532.1
ENST00000651975.1
FGA
fibrinogen alpha chain
chr9_+_107306459 0.07 ENST00000457811.1
RAD23B
RAD23 homolog B, nucleotide excision repair protein
chr4_+_106315534 0.07 ENST00000510207.5
AIMP1
aminoacyl tRNA synthetase complex interacting multifunctional protein 1
chr13_+_75549477 0.07 ENST00000618773.4
UCHL3
ubiquitin C-terminal hydrolase L3
chr5_-_83720813 0.07 ENST00000515590.1
ENST00000274341.9
HAPLN1
hyaluronan and proteoglycan link protein 1
chr3_+_151814102 0.06 ENST00000232892.12
AADAC
arylacetamide deacetylase
chr11_-_45286265 0.06 ENST00000020926.8
SYT13
synaptotagmin 13
chr9_-_21351378 0.06 ENST00000380210.1
IFNA6
interferon alpha 6
chr5_-_157109025 0.06 ENST00000307851.9
HAVCR2
hepatitis A virus cellular receptor 2
chr10_+_80131660 0.06 ENST00000372270.6
PLAC9
placenta associated 9
chr1_+_212565334 0.06 ENST00000366981.8
ENST00000366987.6
ATF3
activating transcription factor 3
chr20_+_56412112 0.05 ENST00000360314.7
CASS4
Cas scaffold protein family member 4
chr4_-_64409444 0.05 ENST00000381210.8
ENST00000507440.5
TECRL
trans-2,3-enoyl-CoA reductase like
chr6_+_29396555 0.05 ENST00000623183.1
OR12D2
olfactory receptor family 12 subfamily D member 2
chr6_-_26017779 0.04 ENST00000244573.5
H1-1
H1.1 linker histone, cluster member
chr4_-_154612635 0.04 ENST00000407946.5
ENST00000405164.5
ENST00000336098.8
ENST00000393846.6
ENST00000404648.7
ENST00000443553.5
FGG
fibrinogen gamma chain
chr11_+_122838492 0.04 ENST00000227348.9
CRTAM
cytotoxic and regulatory T cell molecule
chrX_-_18220878 0.04 ENST00000380033.9
BEND2
BEN domain containing 2
chr13_+_75549734 0.04 ENST00000563635.5
ENST00000377595.8
ENSG00000261553.5
UCHL3
novel transcript
ubiquitin C-terminal hydrolase L3
chr11_-_82846128 0.04 ENST00000679809.1
ENST00000680186.1
ENST00000681592.1
PRCP
prolylcarboxypeptidase
chr6_+_29587455 0.03 ENST00000383640.4
OR2H2
olfactory receptor family 2 subfamily H member 2
chr1_-_159714581 0.03 ENST00000255030.9
ENST00000437342.1
ENST00000368112.5
ENST00000368111.5
ENST00000368110.1
CRP
C-reactive protein
chr5_-_43043170 0.03 ENST00000314890.3
ANXA2R
annexin A2 receptor
chr20_+_56412393 0.03 ENST00000679529.1
CASS4
Cas scaffold protein family member 4
chr5_+_55851378 0.02 ENST00000396836.6
ENST00000359040.10
IL31RA
interleukin 31 receptor A
chr16_-_21857657 0.02 ENST00000341400.11
ENST00000518761.8
ENST00000682606.1
NPIPB4
nuclear pore complex interacting protein family member B4
chr5_-_177780633 0.02 ENST00000513554.5
ENST00000440605.7
FAM153A
family with sequence similarity 153 member A
chr7_+_117611617 0.02 ENST00000468795.1
CFTR
CF transmembrane conductance regulator
chr8_+_32721823 0.02 ENST00000539990.3
ENST00000519240.5
NRG1
neuregulin 1
chr1_+_12857086 0.02 ENST00000240189.2
PRAMEF2
PRAME family member 2
chr4_+_73481737 0.02 ENST00000226355.5
AFM
afamin
chr7_-_142258027 0.02 ENST00000552471.1
ENST00000547058.6
PRSS58
serine protease 58
chr2_+_61905646 0.02 ENST00000311832.5
COMMD1
copper metabolism domain containing 1
chr2_+_27537380 0.02 ENST00000447166.2
C2orf16
chromosome 2 open reading frame 16
chr4_+_112818088 0.01 ENST00000673044.1
ENST00000672696.1
ENST00000672315.1
ENST00000672088.1
ENST00000671793.1
ENST00000672402.1
ENST00000671825.1
ENST00000672312.1
ENST00000672830.1
ENST00000672731.1
ENST00000671854.1
ENST00000672350.1
ENST00000672684.1
ENST00000672934.1
ENST00000673546.1
ENST00000673573.1
ENST00000503423.6
ENST00000673255.1
ENST00000671893.1
ENST00000672246.1
ENST00000672930.1
ENST00000673334.1
ENST00000673453.1
ENST00000673555.1
ENST00000672880.1
ENST00000672990.1
ENST00000673430.1
ENST00000673298.1
ENST00000672068.1
ENST00000672362.1
ENST00000672793.1
ENST00000672209.1
ENST00000671756.1
ENST00000671809.1
ENST00000671906.1
ENST00000672090.1
ENST00000672177.1
ENST00000672759.1
ENST00000672965.1
ENST00000673109.1
ENST00000503271.5
ENST00000506722.5
ENST00000673536.1
ENST00000672986.1
ANK2
ankyrin 2
chr16_-_20352707 0.01 ENST00000396134.6
ENST00000573567.5
ENST00000570757.5
ENST00000396138.9
ENST00000571174.5
ENST00000576688.2
UMOD
uromodulin
chr6_-_8102046 0.01 ENST00000488226.2
EEF1E1
eukaryotic translation elongation factor 1 epsilon 1
chr15_-_100341899 0.01 ENST00000568565.2
ENST00000268070.9
ADAMTS17
ADAM metallopeptidase with thrombospondin type 1 motif 17
chr1_-_9943314 0.01 ENST00000377223.6
ENST00000377213.1
LZIC
leucine zipper and CTNNBIP1 domain containing
chr4_+_112818032 0.01 ENST00000672356.1
ENST00000672955.1
ANK2
ankyrin 2
chr5_-_157109115 0.01 ENST00000522593.5
HAVCR2
hepatitis A virus cellular receptor 2
chr17_-_10026265 0.01 ENST00000437099.6
ENST00000396115.6
GAS7
growth arrest specific 7
chr2_+_209771972 0.01 ENST00000439458.5
ENST00000272845.10
UNC80
unc-80 homolog, NALCN channel complex subunit
chr19_+_3136026 0.00 ENST00000262958.4
GNA15
G protein subunit alpha 15
chr1_+_12791397 0.00 ENST00000332296.7
PRAMEF1
PRAME family member 1
chr10_+_102226293 0.00 ENST00000370005.4
ELOVL3
ELOVL fatty acid elongase 3
chr9_-_136748515 0.00 ENST00000341206.9
LCN6
lipocalin 6
chr16_+_22513523 0.00 ENST00000538606.5
ENST00000451409.5
ENST00000424340.5
ENST00000517539.5
ENST00000528249.5
NPIPB5
nuclear pore complex interacting protein family member B5

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.7 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.2 GO:1904823 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.2 GO:2001027 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.4 GO:0046102 inosine metabolic process(GO:0046102)
0.0 0.5 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.5 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.1 GO:1903487 regulation of lactation(GO:1903487)
0.0 0.1 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.2 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.2 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.1 GO:2000910 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.0 0.1 GO:0019086 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086)
0.0 2.6 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.2 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.1 GO:1901257 negative regulation of interleukin-3 production(GO:0032712) negative regulation of granulocyte colony-stimulating factor production(GO:0071656) negative regulation of macrophage colony-stimulating factor production(GO:1901257)
0.0 0.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.8 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.8 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.3 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.3 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.3 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.0 0.3 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.2 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.0 0.5 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.7 GO:0032982 myosin filament(GO:0032982)
0.0 0.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.2 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.2 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 0.5 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.2 GO:0002060 purine nucleobase binding(GO:0002060)
0.1 0.2 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.6 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.8 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.2 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.2 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.7 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0098960 postsynaptic neurotransmitter receptor activity(GO:0098960)
0.0 0.8 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.2 GO:0015643 guanylate cyclase activity(GO:0004383) toxic substance binding(GO:0015643)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.7 PID ATR PATHWAY ATR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism