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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for SMAD2

Z-value: 0.53

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Transcription factors associated with SMAD2

Gene Symbol Gene ID Gene Info
SMAD2
ENSG00000175387.16 SMAD2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SMAD2hg38_v1_chr18_-_47931107_47931146-0.542.0e-03Click!

Activity profile of SMAD2 motif

Sorted Z-values of SMAD2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SMAD2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chrX_-_48470243 1.87 ENST00000429543.2
ENST00000620913.5
SLC38A5
solute carrier family 38 member 5
chrX_-_48470163 1.84 ENST00000595796.5
SLC38A5
solute carrier family 38 member 5
chr5_-_151686908 1.42 ENST00000231061.9
SPARC
secreted protein acidic and cysteine rich
chr6_-_30687200 1.37 ENST00000399199.7
PPP1R18
protein phosphatase 1 regulatory subunit 18
chr12_-_119804298 1.35 ENST00000678652.1
ENST00000678494.1
CIT
citron rho-interacting serine/threonine kinase
chr12_+_53050179 1.33 ENST00000546602.5
ENST00000552570.5
ENST00000549700.5
TNS2
tensin 2
chrX_-_107775740 1.30 ENST00000372383.9
TSC22D3
TSC22 domain family member 3
chr19_-_43781249 1.30 ENST00000615047.4
KCNN4
potassium calcium-activated channel subfamily N member 4
chr12_-_119803383 1.23 ENST00000392520.2
ENST00000678677.1
ENST00000679249.1
ENST00000676849.1
CIT
citron rho-interacting serine/threonine kinase
chrX_-_107775951 1.21 ENST00000315660.8
ENST00000372384.6
ENST00000502650.1
ENST00000506724.1
TSC22D3
TSC22 domain family member 3
chr11_-_107858777 1.21 ENST00000525815.6
SLC35F2
solute carrier family 35 member F2
chr9_+_122375286 1.03 ENST00000373698.7
PTGS1
prostaglandin-endoperoxide synthase 1
chr17_-_7394240 1.00 ENST00000576362.5
ENST00000571078.5
PLSCR3
phospholipid scramblase 3
chr17_-_7394514 0.95 ENST00000571802.1
ENST00000619711.5
ENST00000576201.5
ENST00000573213.1
ENST00000324822.15
PLSCR3
phospholipid scramblase 3
chr16_+_55479188 0.93 ENST00000219070.9
MMP2
matrix metallopeptidase 2
chr9_+_125747345 0.92 ENST00000342287.9
ENST00000373489.10
ENST00000373487.8
PBX3
PBX homeobox 3
chr1_-_149936816 0.87 ENST00000439741.4
MTMR11
myotubularin related protein 11
chr9_+_34990250 0.83 ENST00000454002.6
ENST00000545841.5
DNAJB5
DnaJ heat shock protein family (Hsp40) member B5
chr2_-_227164194 0.83 ENST00000396625.5
COL4A4
collagen type IV alpha 4 chain
chr16_+_28878480 0.81 ENST00000395503.9
ATP2A1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr1_-_149936324 0.79 ENST00000369140.7
MTMR11
myotubularin related protein 11
chr7_+_129126518 0.79 ENST00000467614.2
ENSG00000230626.4
novel protein similar to mitogen-activated protein kinase kinase 2 MAP2K2
chr17_-_78925376 0.78 ENST00000262768.11
TIMP2
TIMP metallopeptidase inhibitor 2
chr4_+_37244735 0.75 ENST00000309447.6
NWD2
NACHT and WD repeat domain containing 2
chr20_+_44715360 0.73 ENST00000190983.5
CCN5
cellular communication network factor 5
chr16_+_28878382 0.72 ENST00000357084.7
ATP2A1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr20_+_44714853 0.71 ENST00000372865.4
CCN5
cellular communication network factor 5
chr17_+_4950147 0.69 ENST00000522301.5
ENO3
enolase 3
chr12_+_53050014 0.69 ENST00000314250.11
TNS2
tensin 2
chr22_+_37560472 0.65 ENST00000430687.1
ENST00000249014.5
CDC42EP1
CDC42 effector protein 1
chr22_-_37427433 0.65 ENST00000452946.1
ENST00000402918.7
ELFN2
ELFN2
extracellular leucine rich repeat and fibronectin type III domain containing 2
extracellular leucine rich repeat and fibronectin type III domain containing 2
chr12_-_52814106 0.63 ENST00000551956.2
KRT4
keratin 4
chr10_+_71212524 0.58 ENST00000335350.10
UNC5B
unc-5 netrin receptor B
chr19_-_14114156 0.58 ENST00000589994.6
PRKACA
protein kinase cAMP-activated catalytic subunit alpha
chr7_-_102616692 0.58 ENST00000521076.5
ENST00000462172.5
ENST00000522801.5
ENST00000262940.12
ENST00000449970.6
RASA4
RAS p21 protein activator 4
chr12_-_6631632 0.58 ENST00000431922.1
LPAR5
lysophosphatidic acid receptor 5
chr10_-_14330879 0.58 ENST00000357447.7
FRMD4A
FERM domain containing 4A
chr7_-_75994574 0.58 ENST00000439537.5
ENST00000493111.7
ENST00000417509.5
ENST00000485200.1
TMEM120A
transmembrane protein 120A
chr21_-_5973383 0.57 ENST00000464664.3
ENSG00000274559.3
novel histone H2B family protein
chr22_-_43891995 0.54 ENST00000438734.1
ENST00000597664.6
ENST00000216177.8
ENST00000593866.5
ENST00000381198.6
PNPLA5
patatin like phospholipase domain containing 5
chr3_+_50279080 0.53 ENST00000316436.4
LSMEM2
leucine rich single-pass membrane protein 2
chr1_+_37474572 0.51 ENST00000373087.7
ZC3H12A
zinc finger CCCH-type containing 12A
chr5_-_64768619 0.51 ENST00000513458.9
SREK1IP1
SREK1 interacting protein 1
chr7_-_102517755 0.51 ENST00000306682.6
ENST00000465829.6
ENST00000541662.5
RASA4B
RAS p21 protein activator 4B
chr4_-_41214450 0.50 ENST00000513140.5
APBB2
amyloid beta precursor protein binding family B member 2
chr19_-_41353904 0.50 ENST00000221930.6
TGFB1
transforming growth factor beta 1
chr5_+_71455636 0.47 ENST00000358731.9
ENST00000380675.3
BDP1
B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
chr19_-_49362376 0.47 ENST00000601519.5
ENST00000593945.6
ENST00000539846.5
ENST00000596757.1
ENST00000311227.6
TEAD2
TEA domain transcription factor 2
chr16_+_2009870 0.47 ENST00000567649.1
NPW
neuropeptide W
chr20_+_37346128 0.46 ENST00000373578.7
SRC
SRC proto-oncogene, non-receptor tyrosine kinase
chr11_-_101583985 0.46 ENST00000344327.8
TRPC6
transient receptor potential cation channel subfamily C member 6
chr22_+_37639660 0.45 ENST00000649765.2
ENST00000451997.6
SH3BP1
ENSG00000285304.1
SH3 domain binding protein 1
novel protein
chr4_-_41214602 0.44 ENST00000508676.5
ENST00000506352.5
ENST00000295974.12
APBB2
amyloid beta precursor protein binding family B member 2
chr11_-_117295485 0.41 ENST00000680971.1
BACE1
beta-secretase 1
chr13_-_26760741 0.41 ENST00000405846.5
GPR12
G protein-coupled receptor 12
chr21_-_34887148 0.40 ENST00000399240.5
RUNX1
RUNX family transcription factor 1
chr4_-_41214535 0.39 ENST00000508593.6
APBB2
amyloid beta precursor protein binding family B member 2
chr1_+_2476315 0.39 ENST00000419816.6
PLCH2
phospholipase C eta 2
chr1_+_2476284 0.39 ENST00000378486.8
PLCH2
phospholipase C eta 2
chr6_+_34514853 0.38 ENST00000538621.2
PACSIN1
protein kinase C and casein kinase substrate in neurons 1
chr14_-_106038355 0.37 ENST00000390597.3
IGHV2-5
immunoglobulin heavy variable 2-5
chr3_+_130850585 0.37 ENST00000505330.5
ENST00000504381.5
ENST00000507488.6
ATP2C1
ATPase secretory pathway Ca2+ transporting 1
chr14_-_104978360 0.37 ENST00000333244.6
AHNAK2
AHNAK nucleoprotein 2
chr21_-_37267511 0.37 ENST00000398998.1
VPS26C
VPS26 endosomal protein sorting factor C
chr17_+_3723889 0.36 ENST00000325418.5
HASPIN
histone H3 associated protein kinase
chr12_-_8612850 0.35 ENST00000229335.11
ENST00000537228.5
AICDA
activation induced cytidine deaminase
chr6_+_43132472 0.35 ENST00000489707.5
PTK7
protein tyrosine kinase 7 (inactive)
chrX_-_47629845 0.34 ENST00000469388.1
ENST00000396992.8
ENST00000377005.6
CFP
complement factor properdin
chr14_-_56810448 0.34 ENST00000339475.10
ENST00000555006.5
ENST00000672264.2
ENST00000554559.5
ENST00000555804.1
OTX2
orthodenticle homeobox 2
chr16_-_2009797 0.34 ENST00000563630.6
ENST00000562103.2
ZNF598
zinc finger protein 598, E3 ubiquitin ligase
chr22_-_36028773 0.34 ENST00000438146.7
RBFOX2
RNA binding fox-1 homolog 2
chr1_-_44017296 0.32 ENST00000357730.6
ENST00000360584.6
ENST00000528803.1
SLC6A9
solute carrier family 6 member 9
chr4_-_102828048 0.32 ENST00000508249.1
UBE2D3
ubiquitin conjugating enzyme E2 D3
chr2_-_20225433 0.32 ENST00000381150.5
SDC1
syndecan 1
chr16_-_4937064 0.31 ENST00000590782.6
ENST00000345988.7
PPL
periplakin
chr5_+_74766981 0.31 ENST00000296802.9
NSA2
NSA2 ribosome biogenesis factor
chrX_-_135098695 0.31 ENST00000433425.4
SMIM10L2B
small integral membrane protein 10 like 2B
chr7_-_14841267 0.31 ENST00000406247.7
ENST00000399322.7
DGKB
diacylglycerol kinase beta
chr12_+_100794769 0.31 ENST00000392977.8
ENST00000546991.1
ENST00000392979.7
ANO4
anoctamin 4
chr22_+_50089879 0.30 ENST00000545383.5
ENST00000262794.10
MOV10L1
Mov10 like RISC complex RNA helicase 1
chr11_-_107719657 0.30 ENST00000525934.1
ENST00000531293.1
SLN
sarcolipin
chr9_+_122519141 0.30 ENST00000340750.1
OR1J4
olfactory receptor family 1 subfamily J member 4
chr3_-_195876635 0.30 ENST00000672669.1
ENST00000672886.1
ENST00000672098.1
ENST00000671767.1
ENST00000672548.1
TNK2
tyrosine kinase non receptor 2
chr18_+_23135452 0.29 ENST00000580153.5
ENST00000256925.12
CABLES1
Cdk5 and Abl enzyme substrate 1
chr20_+_32010429 0.29 ENST00000452892.3
ENST00000262659.12
CCM2L
CCM2 like scaffold protein
chr4_-_39977836 0.29 ENST00000303538.13
ENST00000503396.5
PDS5A
PDS5 cohesin associated factor A
chr1_+_15456727 0.29 ENST00000359621.5
CELA2A
chymotrypsin like elastase 2A
chr11_-_18791768 0.29 ENST00000358540.7
PTPN5
protein tyrosine phosphatase non-receptor type 5
chr2_-_219309484 0.28 ENST00000409251.7
ENST00000451506.5
ENST00000446182.5
PTPRN
protein tyrosine phosphatase receptor type N
chr11_-_3837858 0.28 ENST00000396979.1
RHOG
ras homolog family member G
chr4_-_102828022 0.28 ENST00000502690.5
UBE2D3
ubiquitin conjugating enzyme E2 D3
chr5_+_33440947 0.27 ENST00000455217.6
ENST00000265112.8
TARS1
threonyl-tRNA synthetase 1
chr17_-_42609356 0.27 ENST00000309428.10
RETREG3
reticulophagy regulator family member 3
chr4_-_113761068 0.27 ENST00000342666.9
ENST00000514328.5
ENST00000515496.5
ENST00000508738.5
ENST00000379773.6
CAMK2D
calcium/calmodulin dependent protein kinase II delta
chr1_+_36306359 0.27 ENST00000453908.8
SH3D21
SH3 domain containing 21
chr15_-_82262660 0.26 ENST00000557844.1
ENST00000359445.7
ENST00000268206.12
EFL1
elongation factor like GTPase 1
chr20_-_23086316 0.26 ENST00000246006.5
CD93
CD93 molecule
chrX_+_38561530 0.26 ENST00000378482.7
ENST00000286824.6
TSPAN7
tetraspanin 7
chr20_+_1895365 0.25 ENST00000358771.5
SIRPA
signal regulatory protein alpha
chr10_+_103555124 0.25 ENST00000437579.1
NEURL1
neuralized E3 ubiquitin protein ligase 1
chr10_-_73433550 0.24 ENST00000299432.7
MSS51
MSS51 mitochondrial translational activator
chr5_+_74767234 0.24 ENST00000610426.5
NSA2
NSA2 ribosome biogenesis factor
chrX_+_21940693 0.24 ENST00000404933.7
ENST00000379404.5
SMS
spermine synthase
chr15_+_45587366 0.24 ENST00000220531.9
BLOC1S6
biogenesis of lysosomal organelles complex 1 subunit 6
chr15_+_45587580 0.24 ENST00000566801.5
ENST00000565323.6
ENST00000568816.5
BLOC1S6
biogenesis of lysosomal organelles complex 1 subunit 6
chr9_+_122264603 0.23 ENST00000297908.7
MRRF
mitochondrial ribosome recycling factor
chr16_+_2148603 0.23 ENST00000210187.11
RAB26
RAB26, member RAS oncogene family
chr12_-_21941300 0.23 ENST00000684084.1
ABCC9
ATP binding cassette subfamily C member 9
chr3_+_111674654 0.23 ENST00000636933.1
ENST00000393934.7
ENST00000477665.2
PLCXD2
phosphatidylinositol specific phospholipase C X domain containing 2
chr11_-_18791563 0.23 ENST00000396168.1
PTPN5
protein tyrosine phosphatase non-receptor type 5
chr4_-_103019634 0.22 ENST00000510559.1
ENST00000296422.12
ENST00000394789.7
SLC9B1
solute carrier family 9 member B1
chr16_+_24729641 0.22 ENST00000395799.8
TNRC6A
trinucleotide repeat containing adaptor 6A
chr19_-_14496088 0.22 ENST00000393033.9
ENST00000345425.6
ENST00000586027.5
ENST00000591349.5
ENST00000587210.1
GIPC1
GIPC PDZ domain containing family member 1
chrX_+_153764233 0.22 ENST00000361971.10
PLXNB3
plexin B3
chr11_+_75562056 0.21 ENST00000533603.5
SERPINH1
serpin family H member 1
chrX_+_153764178 0.21 ENST00000538966.5
PLXNB3
plexin B3
chr7_-_92836555 0.21 ENST00000424848.3
CDK6
cyclin dependent kinase 6
chr2_-_219309350 0.21 ENST00000295718.7
PTPRN
protein tyrosine phosphatase receptor type N
chr17_-_3668640 0.21 ENST00000611779.4
TAX1BP3
Tax1 binding protein 3
chr9_-_133131109 0.20 ENST00000372062.8
RALGDS
ral guanine nucleotide dissociation stimulator
chr9_-_134917872 0.20 ENST00000616356.4
ENST00000371806.4
FCN1
ficolin 1
chr5_-_151141631 0.20 ENST00000523714.5
ENST00000521749.5
ANXA6
annexin A6
chr4_-_163613505 0.20 ENST00000339875.9
MARCHF1
membrane associated ring-CH-type finger 1
chr11_+_66857056 0.19 ENST00000309602.5
ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr15_+_68277724 0.19 ENST00000306917.5
FEM1B
fem-1 homolog B
chr6_+_41042557 0.19 ENST00000373158.6
ENST00000470917.1
TSPO2
translocator protein 2
chr1_-_44031352 0.19 ENST00000372306.7
ENST00000475075.6
SLC6A9
solute carrier family 6 member 9
chr1_-_1307861 0.19 ENST00000354700.10
ACAP3
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr19_+_11355386 0.19 ENST00000251473.9
ENST00000591329.5
ENST00000586380.5
PLPPR2
phospholipid phosphatase related 2
chr1_-_149812359 0.18 ENST00000369167.2
ENST00000545683.1
H2BC18
H2B clustered histone 18
chr17_+_42609641 0.18 ENST00000681413.1
ENST00000251413.8
ENST00000591509.5
TUBG1
tubulin gamma 1
chr22_-_38455199 0.18 ENST00000303592.3
KCNJ4
potassium inwardly rectifying channel subfamily J member 4
chr1_-_206003442 0.18 ENST00000623893.1
RAB7B
RAB7B, member RAS oncogene family
chr9_-_98708856 0.18 ENST00000259455.4
GABBR2
gamma-aminobutyric acid type B receptor subunit 2
chr9_-_28670285 0.18 ENST00000379992.6
ENST00000308675.5
ENST00000613945.3
LINGO2
leucine rich repeat and Ig domain containing 2
chr10_+_18261080 0.18 ENST00000377319.8
ENST00000377331.8
CACNB2
calcium voltage-gated channel auxiliary subunit beta 2
chr9_+_33524241 0.18 ENST00000290943.10
ANKRD18B
ankyrin repeat domain 18B
chr12_-_57016517 0.18 ENST00000441881.5
ENST00000458521.7
TAC3
tachykinin precursor 3
chr4_-_102828159 0.18 ENST00000394803.9
UBE2D3
ubiquitin conjugating enzyme E2 D3
chr2_-_17800195 0.18 ENST00000402989.5
ENST00000428868.1
SMC6
structural maintenance of chromosomes 6
chr6_-_143450662 0.17 ENST00000237283.9
ADAT2
adenosine deaminase tRNA specific 2
chr4_-_102827723 0.17 ENST00000349311.12
UBE2D3
ubiquitin conjugating enzyme E2 D3
chr14_-_56810380 0.17 ENST00000672125.1
ENST00000673481.1
OTX2
orthodenticle homeobox 2
chr18_+_3448456 0.17 ENST00000549780.5
TGIF1
TGFB induced factor homeobox 1
chr4_-_113761441 0.17 ENST00000394524.7
CAMK2D
calcium/calmodulin dependent protein kinase II delta
chr4_-_184217854 0.17 ENST00000296741.7
ENPP6
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr19_+_47130782 0.17 ENST00000597808.5
ENST00000413379.7
ENST00000600706.5
ENST00000270225.12
ENST00000598840.5
ENST00000600753.1
ENST00000392776.3
SAE1
SUMO1 activating enzyme subunit 1
chr8_-_94895195 0.17 ENST00000308108.9
ENST00000396133.7
CCNE2
cyclin E2
chr5_+_134526176 0.16 ENST00000681820.1
ENST00000512386.6
ENST00000612830.2
JADE2
jade family PHD finger 2
chr19_+_35775515 0.16 ENST00000378944.9
ARHGAP33
Rho GTPase activating protein 33
chr9_+_15422704 0.16 ENST00000380821.7
ENST00000610884.4
ENST00000421710.5
SNAPC3
small nuclear RNA activating complex polypeptide 3
chrX_-_30577759 0.15 ENST00000378962.4
TASL
TLR adaptor interacting with endolysosomal SLC15A4
chr1_-_206003385 0.15 ENST00000617070.5
RAB7B
RAB7B, member RAS oncogene family
chr9_+_137251261 0.15 ENST00000620243.4
ENST00000388931.7
ENST00000412566.5
ENST00000611378.4
STPG3
sperm-tail PG-rich repeat containing 3
chr4_+_92303946 0.15 ENST00000282020.9
GRID2
glutamate ionotropic receptor delta type subunit 2
chr9_-_14722725 0.15 ENST00000380911.4
CER1
cerberus 1, DAN family BMP antagonist
chr12_+_109900518 0.15 ENST00000312777.9
ENST00000536408.2
TCHP
trichoplein keratin filament binding
chr17_-_3668557 0.15 ENST00000225525.4
TAX1BP3
Tax1 binding protein 3
chr4_-_113761724 0.15 ENST00000511664.6
CAMK2D
calcium/calmodulin dependent protein kinase II delta
chr15_-_73368951 0.15 ENST00000261917.4
HCN4
hyperpolarization activated cyclic nucleotide gated potassium channel 4
chr3_+_40505992 0.15 ENST00000420891.5
ENST00000314529.10
ENST00000418905.1
ZNF620
zinc finger protein 620
chr13_-_96053370 0.15 ENST00000376712.4
ENST00000397618.7
ENST00000376747.8
ENST00000376714.7
ENST00000638479.1
ENST00000621375.5
UGGT2
UDP-glucose glycoprotein glucosyltransferase 2
chr4_-_55592225 0.15 ENST00000295645.9
PDCL2
phosducin like 2
chr5_+_64768921 0.14 ENST00000381070.8
ENST00000508024.1
CWC27
CWC27 spliceosome associated cyclophilin
chr3_-_165196369 0.14 ENST00000475390.2
SLITRK3
SLIT and NTRK like family member 3
chr18_-_3013114 0.14 ENST00000677752.1
LPIN2
lipin 2
chr19_-_14496144 0.14 ENST00000393028.5
GIPC1
GIPC PDZ domain containing family member 1
chr1_-_160070150 0.13 ENST00000644903.1
KCNJ10
potassium inwardly rectifying channel subfamily J member 10
chr12_-_95996302 0.13 ENST00000261208.8
ENST00000538703.5
ENST00000541929.5
HAL
histidine ammonia-lyase
chr11_+_75240761 0.13 ENST00000562197.3
TPBGL
trophoblast glycoprotein like
chr14_+_80955577 0.13 ENST00000642209.1
ENST00000298171.7
TSHR
thyroid stimulating hormone receptor
chr19_-_45785659 0.12 ENST00000537879.1
ENST00000596586.5
ENST00000595946.1
DMWD
ENSG00000268434.5
DM1 locus, WD repeat containing
novel protein
chr19_+_48469354 0.12 ENST00000452733.7
ENST00000641098.1
CYTH2
cytohesin 2
chr6_+_101393699 0.12 ENST00000369134.9
ENST00000684068.1
ENST00000683903.1
ENST00000681975.1
GRIK2
glutamate ionotropic receptor kainate type subunit 2
chr17_-_41424583 0.12 ENST00000225550.4
KRT37
keratin 37
chr3_-_71130963 0.11 ENST00000649695.2
FOXP1
forkhead box P1
chr20_+_58651785 0.11 ENST00000358029.8
STX16
syntaxin 16
chr22_+_24495242 0.10 ENST00000382760.2
ENST00000326010.10
UPB1
beta-ureidopropionase 1
chr1_+_27726005 0.10 ENST00000530324.5
ENST00000234549.11
ENST00000373949.5
ENST00000010299.10
FAM76A
family with sequence similarity 76 member A
chr17_+_75633420 0.09 ENST00000375215.3
SMIM5
small integral membrane protein 5
chr7_+_69967464 0.09 ENST00000664521.1
AUTS2
activator of transcription and developmental regulator AUTS2
chr17_-_42185452 0.09 ENST00000293330.1
HCRT
hypocretin neuropeptide precursor
chr17_-_7207245 0.09 ENST00000649971.1
DLG4
discs large MAGUK scaffold protein 4
chr17_+_68205453 0.09 ENST00000674770.2
AMZ2
archaelysin family metallopeptidase 2
chr5_+_134525649 0.09 ENST00000282605.8
ENST00000681547.2
ENST00000361895.6
ENST00000402835.5
JADE2
jade family PHD finger 2
chr1_-_151146611 0.08 ENST00000341697.7
ENST00000368914.8
SEMA6C
semaphorin 6C
chr3_+_52495330 0.08 ENST00000321725.10
STAB1
stabilin 1
chr5_+_134526100 0.08 ENST00000395003.5
JADE2
jade family PHD finger 2
chr4_-_5888400 0.08 ENST00000397890.6
CRMP1
collapsin response mediator protein 1
chr6_-_27873525 0.08 ENST00000618305.2
H4C13
H4 clustered histone 13
chr1_+_2050387 0.07 ENST00000378567.8
PRKCZ
protein kinase C zeta
chr1_+_99646025 0.07 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
PALMD
palmdelphin
chr12_+_6927946 0.07 ENST00000396684.3
ATN1
atrophin 1
chr15_+_75206398 0.07 ENST00000565074.1
C15orf39
chromosome 15 open reading frame 39
chr7_+_130381092 0.07 ENST00000484324.1
CPA1
carboxypeptidase A1
chr1_-_160070102 0.07 ENST00000638728.1
ENST00000637644.1
KCNJ10
potassium inwardly rectifying channel subfamily J member 10
chr12_+_103930600 0.06 ENST00000680316.1
ENST00000679861.1
HSP90B1
heat shock protein 90 beta family member 1
chr3_-_71130557 0.06 ENST00000497355.7
FOXP1
forkhead box P1
chr7_+_155458129 0.06 ENST00000297375.4
EN2
engrailed homeobox 2
chr5_+_175871570 0.06 ENST00000512824.5
ENST00000393745.8
CPLX2
complexin 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443) relaxation of skeletal muscle(GO:0090076)
0.3 4.2 GO:0015816 glycine transport(GO:0015816)
0.3 2.5 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 1.4 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.2 0.5 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.2 0.9 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.8 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.5 GO:0052251 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.1 0.4 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.9 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.3 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.5 GO:0010587 miRNA catabolic process(GO:0010587) negative regulation by host of viral genome replication(GO:0044828) response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.1 0.3 GO:1904692 positive regulation of type B pancreatic cell proliferation(GO:1904692)
0.1 0.3 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.1 0.3 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 2.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.5 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.1 0.3 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 0.3 GO:0048627 myoblast development(GO:0048627)
0.1 0.2 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1 0.6 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.4 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 2.0 GO:0014850 response to muscle activity(GO:0014850)
0.1 1.3 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.8 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 1.0 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 2.9 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.6 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.7 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.0 0.2 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.4 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 0.2 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.1 GO:0019483 beta-alanine biosynthetic process(GO:0019483)
0.0 0.5 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.6 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.2 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.5 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.2 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.1 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.0 0.5 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.3 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.5 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.2 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.3 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.3 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.6 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.4 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.2 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.0 0.2 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.2 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.3 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.6 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 1.0 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:0002097 tRNA wobble base modification(GO:0002097)
0.0 0.1 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.4 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.0 0.2 GO:0019695 choline metabolic process(GO:0019695)
0.0 1.1 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.1 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.7 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.2 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.4 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.2 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.5 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.1 GO:2000620 innate vocalization behavior(GO:0098582) positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.2 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.1 0.5 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.1 0.5 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.8 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 0.5 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.2 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 1.5 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.2 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.3 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.2 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 1.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.5 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.3 GO:0071546 pi-body(GO:0071546)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 1.1 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.9 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.4 GO:0030137 COPI-coated vesicle(GO:0030137)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.3 2.5 GO:0043426 MRF binding(GO:0043426)
0.2 1.0 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 1.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.5 GO:0001156 TFIIIB-type transcription factor activity(GO:0001026) TFIIIC-class transcription factor binding(GO:0001156)
0.1 0.4 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 2.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.4 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 1.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.5 GO:0071253 connexin binding(GO:0071253)
0.0 0.6 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.4 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.3 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 2.6 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.6 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.6 GO:0098641 GTP-Rho binding(GO:0017049) cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.5 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.2 GO:0016015 morphogen activity(GO:0016015)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 1.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.4 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 2.5 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.6 PID NETRIN PATHWAY Netrin-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 3.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.6 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.6 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.8 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.0 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.0 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 1.2 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 1.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+