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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for SOX14

Z-value: 0.70

Motif logo

Transcription factors associated with SOX14

Gene Symbol Gene ID Gene Info
ENSG00000168875.3 SOX14

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX14hg38_v1_chr3_+_137764296_137764320-0.134.8e-01Click!

Activity profile of SOX14 motif

Sorted Z-values of SOX14 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX14

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_25906457 5.11 ENST00000426559.6
stathmin 1
chr8_+_85463997 4.18 ENST00000285379.10
carbonic anhydrase 2
chr12_-_24902243 3.47 ENST00000538118.5
branched chain amino acid transaminase 1
chr17_-_8210565 3.30 ENST00000577833.5
ENST00000585124.6
ENST00000534871.5
ENST00000583915.1
ENST00000316199.10
ENST00000581511.5
aurora kinase B
chr17_-_8210203 2.05 ENST00000578549.5
ENST00000582368.5
aurora kinase B
chr17_+_4948252 1.94 ENST00000520221.5
enolase 3
chr2_-_207167220 1.86 ENST00000421199.5
ENST00000457962.5
Kruppel like factor 7
chr2_-_224039278 1.82 ENST00000409304.6
ENST00000258405.9
ENST00000454956.1
serpin family E member 2
chr2_+_238848029 1.64 ENST00000448943.2
ENST00000612363.2
twist family bHLH transcription factor 2
chr2_-_207166818 1.64 ENST00000423015.5
Kruppel like factor 7
chr4_-_102345469 1.62 ENST00000356736.5
ENST00000682932.1
solute carrier family 39 member 8
chr13_-_23433676 1.62 ENST00000682547.1
ENST00000455470.6
ENST00000382292.9
sacsin molecular chaperone
chr19_+_16077006 1.54 ENST00000586833.7
ENST00000642221.1
tropomyosin 4
chrX_+_103918872 1.51 ENST00000419165.5
thymosin beta 15B
chr7_-_108003122 1.46 ENST00000393559.2
ENST00000222399.11
ENST00000676777.1
ENST00000439976.6
ENST00000393560.5
ENST00000677793.1
ENST00000679244.1
laminin subunit beta 1
chr7_+_134866831 1.20 ENST00000435928.1
caldesmon 1
chr19_-_55141889 1.19 ENST00000593194.5
troponin T1, slow skeletal type
chr19_+_16076485 1.16 ENST00000643579.2
ENST00000646575.1
tropomyosin 4
chr12_+_15322529 1.15 ENST00000348962.7
protein tyrosine phosphatase receptor type O
chrX_-_38220824 1.12 ENST00000378533.4
ENST00000432886.6
ENST00000544439.5
ENST00000538295.5
sushi repeat containing protein X-linked
chrX_-_107716401 1.10 ENST00000486554.1
ENST00000372390.8
TSC22 domain family member 3
chr19_+_46602050 1.04 ENST00000599839.5
ENST00000596362.1
calmodulin 3
chr7_-_24757413 1.03 ENST00000645220.1
ENST00000409970.6
gasdermin E
chr7_-_45088888 1.02 ENST00000490531.3
NAC alpha domain containing
chr2_+_64988469 1.02 ENST00000531327.5
solute carrier family 1 member 4
chr5_-_112419251 1.02 ENST00000261486.6
erythrocyte membrane protein band 4.1 like 4A
chr1_-_25906411 1.01 ENST00000455785.7
stathmin 1
chr13_-_23433735 1.01 ENST00000423156.2
ENST00000683210.1
ENST00000682775.1
ENST00000684497.1
ENST00000682944.1
ENST00000683489.1
ENST00000684385.1
ENST00000683680.1
sacsin molecular chaperone
chr15_+_85380625 1.00 ENST00000560302.5
A-kinase anchoring protein 13
chr11_+_60924452 0.99 ENST00000453848.7
ENST00000544065.5
ENST00000005286.8
transmembrane protein 132A
chr5_-_177409535 0.89 ENST00000253496.4
coagulation factor XII
chr2_+_101697699 0.86 ENST00000350878.8
ENST00000350198.8
ENST00000324219.8
ENST00000425019.5
mitogen-activated protein kinase kinase kinase kinase 4
chr7_-_50793432 0.79 ENST00000645075.2
ENST00000402497.6
ENST00000439044.7
ENST00000335866.7
growth factor receptor bound protein 10
chr16_-_67183948 0.78 ENST00000561621.5
ENST00000563902.2
ENST00000290881.11
KIAA0895 like
chr15_-_89221558 0.76 ENST00000268125.10
retinaldehyde binding protein 1
chr17_-_74361860 0.75 ENST00000375366.4
BTB domain containing 17
chrX_-_15854743 0.74 ENST00000450644.2
adaptor related protein complex 1 subunit sigma 2
chr8_+_94641074 0.74 ENST00000423620.6
epithelial splicing regulatory protein 1
chr2_+_9206762 0.71 ENST00000315273.4
ENST00000281419.8
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr16_+_8720706 0.70 ENST00000425191.6
ENST00000569156.5
4-aminobutyrate aminotransferase
chrX_+_108044967 0.69 ENST00000415430.7
V-set and immunoglobulin domain containing 1
chr6_-_65707214 0.69 ENST00000370621.7
ENST00000393380.6
ENST00000503581.6
eyes shut homolog
chr17_+_27294076 0.69 ENST00000581440.5
ENST00000583742.1
ENST00000579733.5
ENST00000583193.5
ENST00000581185.5
ENST00000427287.6
ENST00000262394.7
ENST00000348811.6
WD repeat and SOCS box containing 1
chrX_+_108045050 0.67 ENST00000458383.1
ENST00000217957.10
V-set and immunoglobulin domain containing 1
chr4_+_4387039 0.67 ENST00000621129.4
neuronal vesicle trafficking associated 1
chr6_+_30720335 0.66 ENST00000327892.13
tubulin beta class I
chr6_+_113857333 0.66 ENST00000612661.2
myristoylated alanine rich protein kinase C substrate
chr13_+_32031300 0.66 ENST00000642040.1
FRY microtubule binding protein
chr11_+_62419025 0.65 ENST00000278282.3
secretoglobin family 1A member 1
chr11_+_76783349 0.63 ENST00000333090.5
tsukushi, small leucine rich proteoglycan
chr6_+_159761991 0.60 ENST00000367048.5
acetyl-CoA acetyltransferase 2
chr12_-_95217373 0.60 ENST00000549499.1
ENST00000546711.5
ENST00000343958.9
FYVE, RhoGEF and PH domain containing 6
chr2_-_223837553 0.59 ENST00000396654.7
ENST00000396653.2
ENST00000443700.5
adaptor related protein complex 1 subunit sigma 3
chr12_-_54384687 0.58 ENST00000550120.1
ENST00000547210.5
ENST00000394313.7
zinc finger protein 385A
chr11_+_4094775 0.57 ENST00000300738.10
ribonucleotide reductase catalytic subunit M1
chr22_+_19760714 0.57 ENST00000649276.2
T-box transcription factor 1
chr17_-_39197652 0.56 ENST00000394303.8
calcium voltage-gated channel auxiliary subunit beta 1
chr1_-_154183130 0.55 ENST00000368531.6
ENST00000368533.8
tropomyosin 3
chr5_+_150497772 0.55 ENST00000523767.5
N-deacetylase and N-sulfotransferase 1
chr1_-_25905989 0.54 ENST00000399728.5
stathmin 1
chr12_-_52493250 0.54 ENST00000330722.7
keratin 6A
chr5_+_87267792 0.54 ENST00000274376.11
RAS p21 protein activator 1
chr1_+_11691688 0.53 ENST00000294485.6
dorsal inhibitory axon guidance protein
chr7_-_155510158 0.52 ENST00000682997.1
canopy FGF signaling regulator 1
chr14_-_50830479 0.52 ENST00000382043.8
ninein
chr2_-_223837484 0.52 ENST00000446015.6
ENST00000409375.1
adaptor related protein complex 1 subunit sigma 3
chr15_+_73684373 0.52 ENST00000558689.5
ENST00000560786.6
ENST00000318443.10
ENST00000561213.5
CD276 molecule
chr22_+_21632751 0.52 ENST00000292779.4
coiled-coil domain containing 116
chr15_+_73684204 0.51 ENST00000537340.6
ENST00000318424.9
CD276 molecule
chr14_+_51847145 0.51 ENST00000615906.4
G protein subunit gamma 2
chrX_+_104112511 0.50 ENST00000537356.3
ENST00000650639.1
zinc finger CCHC-type containing 18
chr13_-_98977975 0.50 ENST00000376460.5
dedicator of cytokinesis 9
chr3_-_27484374 0.50 ENST00000445684.5
ENST00000425128.6
solute carrier family 4 member 7
chr1_+_28369705 0.49 ENST00000373839.8
phosphatase and actin regulator 4
chr2_-_9630946 0.48 ENST00000446619.1
ENST00000238081.8
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
chr12_-_105084439 0.47 ENST00000258494.14
aldehyde dehydrogenase 1 family member L2
chr10_-_32958164 0.47 ENST00000414670.2
ENST00000677363.1
ENST00000474568.6
ENST00000678591.1
ENST00000678943.1
ENST00000488494.6
ENST00000488427.2
ENST00000302278.8
ENST00000676964.1
ENST00000679187.1
ENST00000678952.1
ENST00000677999.1
ENST00000609742.3
ENST00000678766.1
ENST00000676460.1
ENST00000676659.1
ENST00000417122.7
ENST00000677310.1
integrin subunit beta 1
chr11_+_63986411 0.46 ENST00000538426.6
ENST00000543004.5
OTU deubiquitinase, ubiquitin aldehyde binding 1
chr6_+_96924720 0.46 ENST00000369261.9
kelch like family member 32
chr2_-_121649431 0.46 ENST00000455322.6
ENST00000409078.8
ENST00000263710.8
ENST00000397587.7
ENST00000541377.5
cytoplasmic linker associated protein 1
chr17_-_44363839 0.45 ENST00000293443.12
family with sequence similarity 171 member A2
chr12_+_8513499 0.45 ENST00000299665.3
C-type lectin domain family 4 member D
chr1_-_161044941 0.44 ENST00000368020.5
upstream transcription factor 1
chr1_-_225428813 0.44 ENST00000338179.6
ENST00000425080.1
lamin B receptor
chr18_+_44680875 0.44 ENST00000649279.2
ENST00000677699.1
SET binding protein 1
chr1_-_154183199 0.43 ENST00000323144.12
ENST00000330188.13
ENST00000328159.9
ENST00000611659.4
tropomyosin 3
chrX_-_54496212 0.43 ENST00000375135.4
FYVE, RhoGEF and PH domain containing 1
chr12_+_95217792 0.43 ENST00000436874.6
ENST00000551472.5
ENST00000552821.5
vezatin, adherens junctions transmembrane protein
chr6_-_11382247 0.42 ENST00000397378.7
ENST00000513989.5
ENST00000508546.5
ENST00000504387.5
neural precursor cell expressed, developmentally down-regulated 9
chr5_-_179623659 0.42 ENST00000519056.5
ENST00000506721.5
ENST00000503105.5
ENST00000504348.5
ENST00000508103.5
ENST00000510431.5
ENST00000515158.5
ENST00000393432.8
ENST00000442819.6
heterogeneous nuclear ribonucleoprotein H1
chr1_+_24745396 0.42 ENST00000374379.9
chloride intracellular channel 4
chr9_-_21482313 0.42 ENST00000448696.4
interferon epsilon
chr3_+_183265302 0.42 ENST00000465010.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr1_+_181033887 0.41 ENST00000684662.1
ENST00000434571.7
ENST00000367580.6
ENST00000617803.5
ENST00000683652.1
ENST00000367579.7
ENST00000282990.10
major histocompatibility complex, class I-related
chr2_-_105398978 0.41 ENST00000408995.5
ENST00000530340.6
ENST00000393353.7
ENST00000322142.13
ENST00000344213.9
ENST00000358129.8
four and a half LIM domains 2
chr3_+_26622800 0.40 ENST00000396641.6
leucine rich repeat containing 3B
chr12_+_50504970 0.40 ENST00000301180.10
disco interacting protein 2 homolog B
chr5_+_66828762 0.39 ENST00000490016.6
ENST00000403666.5
ENST00000450827.5
microtubule associated serine/threonine kinase family member 4
chr16_+_3654683 0.39 ENST00000246949.10
deoxyribonuclease 1
chr13_-_98978022 0.38 ENST00000682017.1
ENST00000442173.5
ENST00000627024.2
dedicator of cytokinesis 9
chr2_+_191245185 0.38 ENST00000418908.5
ENST00000339514.8
ENST00000392318.8
myosin IB
chr3_-_27484335 0.37 ENST00000454389.5
ENST00000440156.5
ENST00000437179.5
ENST00000446700.5
ENST00000455077.5
solute carrier family 4 member 7
chr14_+_96363452 0.36 ENST00000438650.5
ENST00000553699.5
ENST00000554182.5
ENST00000555181.6
ENST00000556095.5
GSK3B interacting protein
chr13_-_78603539 0.36 ENST00000377208.7
POU class 4 homeobox 1
chr10_+_10798570 0.35 ENST00000638035.1
ENST00000636488.1
CUGBP Elav-like family member 2
chr8_+_26383043 0.35 ENST00000380629.7
BCL2 interacting protein 3 like
chr11_+_128693887 0.34 ENST00000281428.12
Fli-1 proto-oncogene, ETS transcription factor
chr20_+_45408276 0.34 ENST00000372710.5
ENST00000443296.1
dysbindin domain containing 2
chr2_+_167248638 0.34 ENST00000295237.10
xin actin binding repeat containing 2
chr10_+_119818699 0.34 ENST00000650409.1
inositol polyphosphate-5-phosphatase F
chr5_-_147453888 0.33 ENST00000398514.7
dihydropyrimidinase like 3
chrX_-_139832235 0.32 ENST00000327569.7
ENST00000361648.6
ATPase phospholipid transporting 11C
chr1_-_11691608 0.32 ENST00000376667.7
mitotic arrest deficient 2 like 2
chr5_-_179623098 0.32 ENST00000630639.1
ENST00000329433.10
ENST00000510411.5
heterogeneous nuclear ribonucleoprotein H1
chr6_-_159726871 0.32 ENST00000535561.5
superoxide dismutase 2
chr6_+_30880780 0.31 ENST00000460944.6
ENST00000324771.12
discoidin domain receptor tyrosine kinase 1
chr22_+_23180365 0.31 ENST00000359540.7
ENST00000305877.13
BCR activator of RhoGEF and GTPase
chrX_-_15854791 0.31 ENST00000545766.7
ENST00000380291.5
ENST00000672987.1
ENST00000329235.6
adaptor related protein complex 1 subunit sigma 2
chr1_-_11691646 0.31 ENST00000235310.7
mitotic arrest deficient 2 like 2
chr9_+_134326435 0.30 ENST00000481739.2
retinoid X receptor alpha
chr2_-_9630491 0.30 ENST00000381844.8
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
chr9_+_87498491 0.30 ENST00000622514.4
death associated protein kinase 1
chr1_+_156149657 0.30 ENST00000414683.5
semaphorin 4A
chr17_-_54968697 0.29 ENST00000571584.1
cytochrome c oxidase copper chaperone COX11
chr17_+_41226648 0.29 ENST00000377721.3
keratin associated protein 9-2
chr11_+_128694052 0.29 ENST00000527786.7
ENST00000534087.3
Fli-1 proto-oncogene, ETS transcription factor
chr12_-_8662808 0.29 ENST00000359478.7
ENST00000396549.6
microfibril associated protein 5
chr19_+_58183029 0.29 ENST00000424679.6
ENST00000617501.5
ENST00000345813.7
zinc finger protein 274
chr2_+_222671651 0.28 ENST00000446656.4
monoacylglycerol O-acyltransferase 1
chr3_-_57597443 0.28 ENST00000463880.1
ADP ribosylation factor 4
chr9_+_109640779 0.27 ENST00000374531.6
PALM2 and AKAP2 fusion
chr1_-_241640347 0.27 ENST00000366554.3
ENST00000366553.3
opsin 3
CHM like Rab escort protein
chr18_+_3448456 0.27 ENST00000549780.5
TGFB induced factor homeobox 1
chr17_-_64230727 0.26 ENST00000583097.5
ENST00000615733.4
testis expressed 2
chr16_+_6483728 0.26 ENST00000675459.1
ENST00000551752.5
RNA binding fox-1 homolog 1
chr16_+_77199408 0.25 ENST00000378644.5
synaptonemal complex central element protein 1 like
chr7_-_128775793 0.24 ENST00000249389.3
opsin 1, short wave sensitive
chr17_+_7352142 0.24 ENST00000333751.8
potassium channel tetramerization domain containing 11
chr16_+_6483379 0.23 ENST00000552089.5
RNA binding fox-1 homolog 1
chr20_-_44521989 0.23 ENST00000342374.5
ENST00000255175.5
serine incorporator 3
chr3_-_120450981 0.23 ENST00000424703.6
ENST00000469005.1
ENST00000295633.8
follistatin like 1
chr1_-_162023632 0.23 ENST00000367940.2
olfactomedin like 2B
chr9_-_113299196 0.23 ENST00000441031.3
ring finger protein 183
chr1_-_79006773 0.22 ENST00000671209.1
adhesion G protein-coupled receptor L4
chr6_-_127519191 0.22 ENST00000525778.5
SOGA family member 3
chr19_+_49363730 0.22 ENST00000596402.1
ENST00000221498.7
dickkopf like acrosomal protein 1
chr6_+_96924614 0.22 ENST00000536676.5
ENST00000539200.5
ENST00000544166.5
kelch like family member 32
chr6_-_127518875 0.21 ENST00000465909.2
ENST00000467753.1
SOGA family member 3
chr12_-_57752265 0.21 ENST00000547281.5
ENST00000257904.11
ENST00000546489.5
ENST00000552388.1
cyclin dependent kinase 4
chr18_+_23135452 0.21 ENST00000580153.5
ENST00000256925.12
Cdk5 and Abl enzyme substrate 1
chr17_+_7351889 0.21 ENST00000576980.2
potassium channel tetramerization domain containing 11
chr8_-_22156789 0.21 ENST00000306317.7
leucine rich repeat LGI family member 3
chr1_-_79006680 0.20 ENST00000370742.4
ENST00000656841.1
adhesion G protein-coupled receptor L4
chr19_+_4969105 0.20 ENST00000611640.4
ENST00000159111.9
ENST00000588337.5
ENST00000381759.8
lysine demethylase 4B
chrX_+_12975216 0.20 ENST00000380635.5
thymosin beta 4 X-linked
chr7_-_122304738 0.19 ENST00000442488.7
FEZ family zinc finger 1
chr12_-_57752345 0.19 ENST00000551800.5
ENST00000549606.5
ENST00000312990.10
cyclin dependent kinase 4
chr12_+_69239627 0.19 ENST00000551516.1
cleavage and polyadenylation specific factor 6
chr2_-_203535253 0.18 ENST00000457812.5
ENST00000319170.10
ENST00000630330.2
ENST00000308091.8
ENST00000453034.5
ENST00000420371.2
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr1_-_11691471 0.18 ENST00000376672.5
mitotic arrest deficient 2 like 2
chr3_-_120094436 0.18 ENST00000264235.13
ENST00000677034.1
glycogen synthase kinase 3 beta
chr17_+_40121955 0.18 ENST00000398532.9
MSL complex subunit 1
chr1_+_201888864 0.18 ENST00000362011.7
shisa family member 4
chr4_-_99321362 0.17 ENST00000625860.2
ENST00000305046.13
ENST00000506651.5
alcohol dehydrogenase 1B (class I), beta polypeptide
chr5_+_40909490 0.17 ENST00000313164.10
complement C7
chr19_-_8343255 0.17 ENST00000330915.7
ENST00000593649.5
ENST00000595639.1
KN motif and ankyrin repeat domains 3
chr18_-_74457302 0.17 ENST00000343998.8
divergent protein kinase domain 1C
chr18_+_3447562 0.17 ENST00000618001.4
TGFB induced factor homeobox 1
chr11_-_18791768 0.17 ENST00000358540.7
protein tyrosine phosphatase non-receptor type 5
chr8_-_80080816 0.16 ENST00000520527.5
ENST00000517427.5
ENST00000379097.7
ENST00000448733.3
tumor protein D52
chr1_-_201154418 0.16 ENST00000435310.5
ENST00000485839.6
transmembrane protein 9
chr17_-_54968637 0.16 ENST00000299335.8
cytochrome c oxidase copper chaperone COX11
chr19_-_19628197 0.16 ENST00000586703.1
ENST00000591042.1
ENST00000407877.8
lysophosphatidic acid receptor 2
chr19_+_49363923 0.16 ENST00000597546.1
dickkopf like acrosomal protein 1
chr19_+_58183375 0.16 ENST00000326804.8
ENST00000610905.4
ENST00000597528.1
zinc finger protein 274
chr1_-_26913964 0.16 ENST00000254227.4
nuclear receptor subfamily 0 group B member 2
chr1_+_65420643 0.16 ENST00000371059.7
ENST00000371060.7
ENST00000349533.11
ENST00000371065.9
ENST00000488747.5
ENST00000484243.1
ENST00000613538.1
leptin receptor
leptin receptor overlapping transcript
chr9_-_137221323 0.15 ENST00000391553.2
ENST00000392827.2
ring finger protein 208
chr9_-_113299765 0.15 ENST00000478815.1
ring finger protein 183
chr1_-_201154459 0.15 ENST00000414605.2
ENST00000367330.6
ENST00000367334.9
ENST00000367332.5
transmembrane protein 9
chr11_-_70661762 0.15 ENST00000357171.7
ENST00000412252.5
ENST00000449833.6
ENST00000338508.8
SH3 and multiple ankyrin repeat domains 2
chr3_+_128051610 0.15 ENST00000464451.5
SEC61 translocon subunit alpha 1
chr14_-_50561119 0.14 ENST00000555216.5
mitogen-activated protein kinase kinase kinase kinase 5
chr1_+_205043165 0.13 ENST00000640428.1
contactin 2
chr8_+_141417902 0.12 ENST00000681443.1
protein tyrosine phosphatase 4A3
chr17_-_39197696 0.12 ENST00000394310.7
ENST00000622445.4
ENST00000344140.5
calcium voltage-gated channel auxiliary subunit beta 1
chr4_-_119627631 0.12 ENST00000264805.9
phosphodiesterase 5A
chr1_+_40450053 0.12 ENST00000484445.5
ENST00000411995.6
ZFP69 zinc finger protein B
chr14_+_66486356 0.12 ENST00000636229.1
coiled-coil domain containing 196
chr1_+_52056255 0.11 ENST00000489308.6
basic transcription factor 3 like 4
chr1_-_23369813 0.11 ENST00000314011.9
zinc finger protein 436
chr11_+_65027402 0.11 ENST00000377244.8
ENST00000534637.5
ENST00000524831.5
sorting nexin 15
chr1_+_23019415 0.11 ENST00000465864.2
ENST00000356634.7
ENST00000400181.9
lysine demethylase 1A
chr11_-_66026473 0.10 ENST00000312106.6
cation channel sperm associated 1
chr3_-_57597325 0.10 ENST00000496292.5
ENST00000489843.1
ENST00000303436.11
ADP ribosylation factor 4
chr19_+_48469354 0.10 ENST00000452733.7
ENST00000641098.1
cytohesin 2
chr5_-_177473609 0.10 ENST00000477391.6
ENST00000393565.5
ENST00000309007.9
drebrin 1
chr11_-_36289408 0.10 ENST00000263401.10
ENST00000532705.1
ENST00000452374.6
COMM domain containing 9
chr19_-_17264718 0.10 ENST00000431146.6
ENST00000594190.5
USH1 protein network component harmonin binding protein 1
chr19_+_1275508 0.09 ENST00000409293.6
family with sequence similarity 174 member C

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0042938 dipeptide transport(GO:0042938)
1.1 5.4 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.7 3.5 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.6 6.7 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.4 1.8 GO:0061107 seminal vesicle development(GO:0061107)
0.3 1.1 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.2 0.9 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.2 0.9 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.2 0.6 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.2 0.7 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.2 1.7 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.2 0.7 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.2 0.5 GO:0061386 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.2 0.5 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.2 0.6 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.2 0.5 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.1 1.0 GO:0015808 L-alanine transport(GO:0015808)
0.1 0.6 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 0.8 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.5 GO:0051710 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
0.1 1.2 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1 0.7 GO:0010193 response to ozone(GO:0010193)
0.1 1.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 1.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.4 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 2.6 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 0.4 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1 0.3 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.1 0.5 GO:0010710 regulation of collagen catabolic process(GO:0010710)
0.1 0.3 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.1 0.4 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.1 0.3 GO:0060268 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of respiratory burst(GO:0060268) negative regulation of blood vessel remodeling(GO:0060313)
0.1 0.5 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.5 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.1 0.4 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086)
0.1 0.5 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 0.5 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.3 GO:0003069 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.1 1.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.7 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.1 1.0 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 3.7 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.1 GO:0071206 establishment of protein localization to juxtaparanode region of axon(GO:0071206)
0.0 0.8 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.2 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339) negative regulation of type B pancreatic cell development(GO:2000077)
0.0 0.4 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.3 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 2.2 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 2.6 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.8 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.3 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.2 GO:0009597 detection of virus(GO:0009597)
0.0 0.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 1.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.6 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.1 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.5 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.6 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.6 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.2 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0 1.4 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.0 0.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.5 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.2 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.8 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.9 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.8 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.4 GO:0032620 interleukin-17 production(GO:0032620)
0.0 2.8 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.2 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.7 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.3 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.0 GO:0050904 diapedesis(GO:0050904)
0.0 0.5 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.0 0.2 GO:0007130 synaptonemal complex assembly(GO:0007130)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.4 GO:0032133 chromosome passenger complex(GO:0032133)
0.5 1.5 GO:0005606 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.3 0.7 GO:0001674 female germ cell nucleus(GO:0001674)
0.3 1.8 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.2 3.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.2 2.6 GO:0070852 cell body fiber(GO:0070852)
0.2 1.0 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.2 1.9 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 0.7 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.2 0.5 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
0.1 0.8 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.6 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.5 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 1.2 GO:0030478 actin cap(GO:0030478)
0.1 0.4 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.7 GO:0098845 postsynaptic endosome(GO:0098845)
0.1 1.2 GO:0005861 troponin complex(GO:0005861)
0.1 0.5 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.4 GO:0016589 NURF complex(GO:0016589)
0.0 0.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.7 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 4.6 GO:0005902 microvillus(GO:0005902)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 2.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 1.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.5 GO:0031941 filamentous actin(GO:0031941)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.5 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.6 5.4 GO:0035174 histone serine kinase activity(GO:0035174)
0.4 4.2 GO:0004064 arylesterase activity(GO:0004064)
0.2 1.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 0.7 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.2 0.5 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.2 0.8 GO:0005502 11-cis retinal binding(GO:0005502)
0.2 0.6 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.1 0.4 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 1.0 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.1 0.4 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.5 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 1.2 GO:0043426 MRF binding(GO:0043426)
0.1 0.7 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.6 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.9 GO:0004111 creatine kinase activity(GO:0004111)
0.1 2.6 GO:0070628 proteasome binding(GO:0070628)
0.1 0.5 GO:0043515 kinetochore binding(GO:0043515)
0.1 1.2 GO:0031014 troponin T binding(GO:0031014)
0.1 0.4 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.1 0.3 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886) vitamin D response element binding(GO:0070644)
0.1 0.9 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.7 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.5 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.5 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.1 1.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 1.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.8 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.5 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.3 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.9 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 3.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.4 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.7 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.7 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.4 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 5.9 PID AURORA A PATHWAY Aurora A signaling
0.1 1.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 3.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.6 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.8 PID IGF1 PATHWAY IGF1 pathway
0.0 0.7 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 3.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 5.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 5.4 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.5 REACTOME OPSINS Genes involved in Opsins
0.0 0.9 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.8 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 1.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.2 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions