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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for SOX30

Z-value: 0.35

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Transcription factors associated with SOX30

Gene Symbol Gene ID Gene Info
SOX30
ENSG00000039600.11 SOX30

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX30hg38_v1_chr5_-_157652364_157652385,
hg38_v1_chr5_-_157652432_157652443		-0.202.9e-01Click!

Activity profile of SOX30 motif

Sorted Z-values of SOX30 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX30

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr10_-_27981805 1.46 ENST00000673512.1
ENST00000672877.1
ENST00000480504.1
ODAD2
outer dynein arm docking complex subunit 2
chr6_+_131637296 0.98 ENST00000358229.6
ENST00000357639.8
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr13_-_85799400 0.86 ENST00000647374.2
SLITRK6
SLIT and NTRK like family member 6
chr15_-_48963912 0.80 ENST00000332408.9
SHC4
SHC adaptor protein 4
chr12_-_49187369 0.77 ENST00000547939.6
TUBA1A
tubulin alpha 1a
chr6_-_139291987 0.76 ENST00000358430.8
TXLNB
taxilin beta
chr12_-_10130241 0.74 ENST00000353231.9
ENST00000525605.1
CLEC7A
C-type lectin domain containing 7A
chr1_+_47023659 0.64 ENST00000371901.4
CYP4X1
cytochrome P450 family 4 subfamily X member 1
chr3_+_181711915 0.52 ENST00000325404.3
SOX2
SRY-box transcription factor 2
chr4_+_76435216 0.50 ENST00000296043.7
SHROOM3
shroom family member 3
chr12_-_10130143 0.47 ENST00000298523.9
ENST00000396484.6
ENST00000310002.4
ENST00000304084.13
CLEC7A
C-type lectin domain containing 7A
chr3_-_149221811 0.43 ENST00000455472.3
ENST00000264613.11
CP
ceruloplasmin
chr11_+_63369779 0.42 ENST00000279178.4
SLC22A9
solute carrier family 22 member 9
chr5_-_147081428 0.41 ENST00000394413.7
PPP2R2B
protein phosphatase 2 regulatory subunit Bbeta
chr5_-_160852200 0.41 ENST00000327245.10
ATP10B
ATPase phospholipid transporting 10B (putative)
chr5_+_140855882 0.40 ENST00000562220.2
ENST00000307360.6
ENST00000506939.6
PCDHA10
protocadherin alpha 10
chr8_+_24294044 0.39 ENST00000265769.9
ADAM28
ADAM metallopeptidase domain 28
chr11_-_85719160 0.38 ENST00000389958.7
ENST00000527794.5
SYTL2
synaptotagmin like 2
chr12_-_10130082 0.37 ENST00000533022.5
CLEC7A
C-type lectin domain containing 7A
chr8_+_104339796 0.34 ENST00000622554.1
ENST00000297581.2
DCSTAMP
dendrocyte expressed seven transmembrane protein
chr10_+_68721012 0.33 ENST00000536391.5
ENST00000630771.2
CCAR1
cell division cycle and apoptosis regulator 1
chr5_-_147081462 0.31 ENST00000508267.5
ENST00000504198.5
PPP2R2B
protein phosphatase 2 regulatory subunit Bbeta
chr11_+_36296281 0.31 ENST00000530639.6
PRR5L
proline rich 5 like
chr11_-_85719111 0.30 ENST00000529581.5
ENST00000533577.1
SYTL2
synaptotagmin like 2
chr6_-_134318097 0.28 ENST00000367858.10
ENST00000533224.1
SGK1
serum/glucocorticoid regulated kinase 1
chr7_+_26152188 0.27 ENST00000056233.4
NFE2L3
nuclear factor, erythroid 2 like 3
chr7_+_102285125 0.27 ENST00000536178.3
SH2B2
SH2B adaptor protein 2
chr9_-_71768386 0.25 ENST00000377066.9
ENST00000377044.9
CEMIP2
cell migration inducing hyaluronidase 2
chr1_+_244835616 0.24 ENST00000366528.3
ENST00000411948.7
COX20
cytochrome c oxidase assembly factor COX20
chr11_-_85719045 0.23 ENST00000533057.6
ENST00000533892.5
SYTL2
synaptotagmin like 2
chr20_-_51768327 0.22 ENST00000311637.9
ENST00000338821.6
ATP9A
ATPase phospholipid transporting 9A (putative)
chr8_+_24294107 0.21 ENST00000437154.6
ADAM28
ADAM metallopeptidase domain 28
chr6_+_125919210 0.21 ENST00000438495.6
NCOA7
nuclear receptor coactivator 7
chr6_+_125919296 0.20 ENST00000444128.2
NCOA7
nuclear receptor coactivator 7
chr3_-_11643871 0.20 ENST00000430365.7
VGLL4
vestigial like family member 4
chrX_+_70444827 0.20 ENST00000374360.8
DLG3
discs large MAGUK scaffold protein 3
chr2_+_231708511 0.19 ENST00000341369.11
ENST00000409115.8
ENST00000409683.5
PTMA
prothymosin alpha
chrX_-_117973579 0.18 ENST00000371878.5
KLHL13
kelch like family member 13
chr20_+_38962299 0.15 ENST00000373325.6
ENST00000373323.8
ENST00000252011.8
ENST00000615559.1
DHX35
ENSG00000277581.1
DEAH-box helicase 35
novel transcript, sense intronic to DHX35
chr1_-_156859087 0.15 ENST00000368195.4
INSRR
insulin receptor related receptor
chr5_+_141408000 0.15 ENST00000616430.1
PCDHGB6
protocadherin gamma subfamily B, 6
chr15_-_52652031 0.15 ENST00000546305.6
FAM214A
family with sequence similarity 214 member A
chr3_-_165837412 0.14 ENST00000479451.5
ENST00000488954.1
ENST00000264381.8
BCHE
butyrylcholinesterase
chr7_-_93226449 0.13 ENST00000394468.7
ENST00000453812.2
HEPACAM2
HEPACAM family member 2
chr2_+_222671651 0.13 ENST00000446656.4
MOGAT1
monoacylglycerol O-acyltransferase 1
chr2_-_37671633 0.13 ENST00000295324.4
CDC42EP3
CDC42 effector protein 3
chr13_-_41019289 0.12 ENST00000239882.7
ELF1
E74 like ETS transcription factor 1
chr2_-_157325808 0.12 ENST00000410096.6
ENST00000420719.6
ENST00000409216.5
ENST00000419116.2
ERMN
ermin
chr2_-_37672178 0.11 ENST00000457889.1
CDC42EP3
CDC42 effector protein 3
chr11_-_102452758 0.11 ENST00000398136.7
ENST00000361236.7
TMEM123
transmembrane protein 123
chr17_+_69502397 0.11 ENST00000613873.4
ENST00000589647.5
MAP2K6
mitogen-activated protein kinase kinase 6
chr2_-_37672448 0.11 ENST00000611976.1
CDC42EP3
CDC42 effector protein 3
chr3_-_18424533 0.11 ENST00000417717.6
SATB1
SATB homeobox 1
chr4_+_186227501 0.10 ENST00000446598.6
ENST00000264690.11
ENST00000513864.2
KLKB1
kallikrein B1
chr5_+_141245384 0.10 ENST00000623671.1
ENST00000231173.6
PCDHB15
protocadherin beta 15
chr1_-_167914089 0.10 ENST00000476818.2
ENST00000367848.1
ENST00000367851.9
ENST00000545172.5
ADCY10
adenylate cyclase 10
chr3_-_71305986 0.09 ENST00000647614.1
FOXP1
forkhead box P1
chr3_-_8644782 0.08 ENST00000544814.6
SSUH2
ssu-2 homolog
chrX_-_24672654 0.07 ENST00000379145.5
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr7_+_144070313 0.07 ENST00000641441.1
OR2A25
olfactory receptor family 2 subfamily A member 25
chr1_+_240091866 0.07 ENST00000319653.14
FMN2
formin 2
chr1_+_180928133 0.07 ENST00000367587.1
KIAA1614
KIAA1614
chr1_+_185045515 0.07 ENST00000367509.8
ENST00000367510.8
RNF2
ring finger protein 2
chr19_-_43935234 0.07 ENST00000269973.10
ZNF45
zinc finger protein 45
chr16_+_68539213 0.07 ENST00000570495.5
ENST00000564323.5
ENST00000562156.5
ENST00000573685.5
ENST00000563169.7
ENST00000611381.4
ZFP90
ZFP90 zinc finger protein
chr1_+_185734362 0.07 ENST00000271588.9
HMCN1
hemicentin 1
chr14_-_89954659 0.06 ENST00000555070.1
ENST00000316738.12
ENST00000538485.6
ENST00000556609.5
ENSG00000259053.1
EFCAB11
novel transcript
EF-hand calcium binding domain 11
chr4_+_70592253 0.06 ENST00000322937.10
ENST00000613447.4
AMBN
ameloblastin
chr15_+_56918612 0.06 ENST00000438423.6
ENST00000267811.9
ENST00000333725.10
ENST00000559609.5
TCF12
transcription factor 12
chr11_-_18526885 0.06 ENST00000251968.4
ENST00000536719.5
TSG101
tumor susceptibility 101
chr2_-_162074182 0.05 ENST00000360534.8
DPP4
dipeptidyl peptidase 4
chr5_+_141408032 0.05 ENST00000520790.1
PCDHGB6
protocadherin gamma subfamily B, 6
chr2_-_162074394 0.05 ENST00000676810.1
DPP4
dipeptidyl peptidase 4
chr2_+_178320228 0.05 ENST00000315022.2
OSBPL6
oxysterol binding protein like 6
chr14_-_89954518 0.05 ENST00000556005.1
ENST00000555872.5
EFCAB11
EF-hand calcium binding domain 11
chr11_+_196761 0.05 ENST00000325113.9
ODF3
outer dense fiber of sperm tails 3
chr1_+_40477248 0.05 ENST00000372706.6
ZFP69
ZFP69 zinc finger protein
chr5_+_141172637 0.04 ENST00000231137.6
PCDHB7
protocadherin beta 7
chr5_+_141213919 0.04 ENST00000341948.6
PCDHB13
protocadherin beta 13
chr4_+_70592295 0.04 ENST00000449493.2
AMBN
ameloblastin
chr14_+_35826298 0.04 ENST00000216807.12
BRMS1L
BRMS1 like transcriptional repressor
chr11_-_102705737 0.03 ENST00000260229.5
MMP27
matrix metallopeptidase 27
chr5_-_135399211 0.03 ENST00000312469.8
ENST00000423969.6
MACROH2A1
macroH2A.1 histone
chr22_-_43089375 0.03 ENST00000266254.12
TTLL1
tubulin tyrosine ligase like 1
chr4_-_175812746 0.03 ENST00000393658.6
GPM6A
glycoprotein M6A
chrX_-_143636094 0.03 ENST00000356928.2
SLITRK4
SLIT and NTRK like family member 4
chr15_+_56918763 0.03 ENST00000557843.5
TCF12
transcription factor 12
chr5_+_141392616 0.03 ENST00000398604.3
PCDHGA8
protocadherin gamma subfamily A, 8
chr4_-_68245683 0.02 ENST00000332644.6
TMPRSS11B
transmembrane serine protease 11B
chr7_-_149028452 0.01 ENST00000413966.1
ENST00000652332.1
PDIA4
protein disulfide isomerase family A member 4
chr7_-_83162899 0.01 ENST00000423517.6
PCLO
piccolo presynaptic cytomatrix protein
chrX_+_71283577 0.01 ENST00000420903.6
ENST00000373856.8
ENST00000678437.1
ENST00000678830.1
ENST00000677879.1
ENST00000373841.5
ENST00000276079.13
ENST00000676797.1
ENST00000678660.1
ENST00000678231.1
ENST00000677612.1
ENST00000413858.5
ENST00000450092.6
NONO
non-POU domain containing octamer binding
chr1_-_21176836 0.01 ENST00000634879.2
ENST00000400422.6
ENST00000602326.5
ENST00000411888.5
ENST00000438975.5
ENST00000374935.7
EIF4G3
eukaryotic translation initiation factor 4 gamma 3
chr12_-_10098940 0.01 ENST00000420265.2
CLEC1A
C-type lectin domain family 1 member A
chr17_-_10469558 0.01 ENST00000255381.2
MYH4
myosin heavy chain 4
chr7_+_144000320 0.01 ENST00000641698.1
OR6B1
olfactory receptor family 6 subfamily B member 1
chr3_+_141262614 0.01 ENST00000504264.5
PXYLP1
2-phosphoxylose phosphatase 1
chr11_+_65890627 0.01 ENST00000312579.4
CCDC85B
coiled-coil domain containing 85B
chr1_-_23369813 0.01 ENST00000314011.9
ZNF436
zinc finger protein 436
chr2_+_206939515 0.00 ENST00000272852.4
CPO
carboxypeptidase O

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.9 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.3 GO:0034239 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.1 1.6 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.1 0.9 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.2 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.0 0.5 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.4 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.5 GO:0045176 apical protein localization(GO:0045176)
0.0 0.3 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.7 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0051919 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.0 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:2000395 positive regulation of viral budding via host ESCRT complex(GO:1903774) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.6 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.4 GO:0006825 copper ion transport(GO:0006825)
0.0 0.2 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.0 0.1 GO:0036343 negative regulation of extracellular matrix disassembly(GO:0010716) regulation of cell-cell adhesion mediated by integrin(GO:0033632) psychomotor behavior(GO:0036343)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.3 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.4 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 1.6 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.0 0.4 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.6 GO:0070330 aromatase activity(GO:0070330)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.5 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.3 GO:0017081 chloride channel regulator activity(GO:0017081)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID ATR PATHWAY ATR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases