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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for SOX6

Z-value: 0.41

Motif logo

Transcription factors associated with SOX6

Gene Symbol Gene ID Gene Info
ENSG00000110693.19 SOX6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX6hg38_v1_chr11_-_16408853_16408894-0.251.8e-01Click!

Activity profile of SOX6 motif

Sorted Z-values of SOX6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX6

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_+_23755015 1.02 ENST00000300113.3
calcineurin like EF-hand protein 2
chr5_+_95391361 0.72 ENST00000283357.10
family with sequence similarity 81 member B
chr4_+_41612702 0.63 ENST00000509277.5
LIM and calponin homology domains 1
chr4_+_41612892 0.56 ENST00000509454.5
ENST00000396595.7
ENST00000381753.8
LIM and calponin homology domains 1
chr11_+_73950985 0.43 ENST00000339764.6
DnaJ heat shock protein family (Hsp40) member B13
chr12_-_49187369 0.42 ENST00000547939.6
tubulin alpha 1a
chr13_+_23570370 0.42 ENST00000403372.6
ENST00000248484.9
TNF receptor superfamily member 19
chr17_+_4948252 0.37 ENST00000520221.5
enolase 3
chr7_+_116672357 0.37 ENST00000456159.1
MET proto-oncogene, receptor tyrosine kinase
chr14_-_87993143 0.35 ENST00000622264.4
galactosylceramidase
chr14_-_50561119 0.34 ENST00000555216.5
mitogen-activated protein kinase kinase kinase kinase 5
chr17_+_77451244 0.33 ENST00000591088.5
septin 9
chr9_-_122227525 0.31 ENST00000373755.6
ENST00000373754.6
LIM homeobox 6
chr22_-_50532077 0.30 ENST00000428989.3
ENST00000403326.5
outer dense fiber of sperm tails 3B
chr2_-_207167220 0.30 ENST00000421199.5
ENST00000457962.5
Kruppel like factor 7
chr2_+_10123171 0.29 ENST00000615152.5
ribonucleotide reductase regulatory subunit M2
chr10_+_22928010 0.28 ENST00000376528.8
armadillo repeat containing 3
chr2_-_216695540 0.28 ENST00000233813.5
insulin like growth factor binding protein 5
chr7_+_116672187 0.27 ENST00000318493.11
ENST00000397752.8
MET proto-oncogene, receptor tyrosine kinase
chr3_+_133400046 0.26 ENST00000302334.3
beaded filament structural protein 2
chr14_-_87992838 0.25 ENST00000544807.6
galactosylceramidase
chr11_+_34632464 0.25 ENST00000531794.5
ETS homologous factor
chr15_+_89088417 0.25 ENST00000569550.5
ENST00000565066.5
ENST00000565973.5
ENST00000352732.10
abhydrolase domain containing 2, acylglycerol lipase
chr9_+_136980211 0.24 ENST00000444903.2
prostaglandin D2 synthase
chr12_+_92702983 0.24 ENST00000344636.6
ENST00000544406.2
pleckstrin homology and RhoGEF domain containing G7
chr12_+_92702843 0.23 ENST00000397833.3
pleckstrin homology and RhoGEF domain containing G7
chr12_-_124422523 0.23 ENST00000404121.6
ENST00000356219.7
nuclear receptor corepressor 2
chr2_-_207166818 0.23 ENST00000423015.5
Kruppel like factor 7
chr12_+_56041893 0.23 ENST00000552361.1
ENST00000646449.2
ribosomal protein S26
chr6_-_139291987 0.23 ENST00000358430.8
taxilin beta
chr11_-_119729158 0.22 ENST00000264025.8
nectin cell adhesion molecule 1
chr1_+_244835616 0.22 ENST00000366528.3
ENST00000411948.7
cytochrome c oxidase assembly factor COX20
chr20_-_40689228 0.21 ENST00000373313.3
MAF bZIP transcription factor B
chr5_+_83471736 0.21 ENST00000265077.8
versican
chr2_+_54456311 0.21 ENST00000615901.4
ENST00000356805.9
spectrin beta, non-erythrocytic 1
chr14_-_87993159 0.21 ENST00000393568.8
ENST00000261304.7
galactosylceramidase
chr3_-_197298092 0.19 ENST00000392382.6
discs large MAGUK scaffold protein 1
chr5_-_180591488 0.19 ENST00000292641.4
secretoglobin family 3A member 1
chrX_-_107716401 0.19 ENST00000486554.1
ENST00000372390.8
TSC22 domain family member 3
chr12_+_18738102 0.19 ENST00000317658.5
capping actin protein of muscle Z-line subunit alpha 3
chr11_-_95232514 0.19 ENST00000634898.1
ENST00000542176.1
ENST00000278499.6
sestrin 3
chr16_+_89923333 0.19 ENST00000315491.12
ENST00000555576.5
ENST00000554336.5
ENST00000553967.1
tubulin beta 3 class III
chr15_+_85380625 0.18 ENST00000560302.5
A-kinase anchoring protein 13
chr5_-_88785493 0.18 ENST00000503554.4
myocyte enhancer factor 2C
chr2_+_61065863 0.18 ENST00000402291.6
KIAA1841
chr5_+_140855882 0.18 ENST00000562220.2
ENST00000307360.6
ENST00000506939.6
protocadherin alpha 10
chr2_+_10122730 0.18 ENST00000304567.10
ribonucleotide reductase regulatory subunit M2
chr19_-_17460893 0.17 ENST00000301944.3
nucleoredoxin like 1
chr12_-_76423256 0.17 ENST00000546946.5
oxysterol binding protein like 8
chr9_-_135907228 0.16 ENST00000409386.3
calmodulin regulated spectrin associated protein 1
chr16_+_3018390 0.16 ENST00000573001.5
TNF receptor superfamily member 12A
chr16_+_15434475 0.16 ENST00000566490.5
bMERB domain containing 1
chr12_-_52926459 0.16 ENST00000552150.5
keratin 8
chr1_-_94927079 0.16 ENST00000370206.9
ENST00000394202.8
calponin 3
chr16_+_15434577 0.16 ENST00000300006.9
bMERB domain containing 1
chr8_+_26577843 0.15 ENST00000311151.9
dihydropyrimidinase like 2
chr12_-_9999176 0.15 ENST00000298527.10
ENST00000348658.4
C-type lectin domain family 1 member B
chr14_-_94770102 0.15 ENST00000238558.5
goosecoid homeobox
chr7_-_128775793 0.15 ENST00000249389.3
opsin 1, short wave sensitive
chr6_-_49744378 0.15 ENST00000371159.8
ENST00000263045.9
cysteine rich secretory protein 3
chr3_-_123620571 0.15 ENST00000583087.5
myosin light chain kinase
chr11_+_72080595 0.15 ENST00000647530.1
ENST00000539271.6
ENST00000642510.1
leucine rich transmembrane and O-methyltransferase domain containing
chr3_-_123620496 0.15 ENST00000578202.1
myosin light chain kinase
chr3_-_197298000 0.15 ENST00000664991.1
discs large MAGUK scaffold protein 1
chr12_-_49188811 0.15 ENST00000295766.9
tubulin alpha 1a
chr14_-_106470788 0.14 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr20_-_17531366 0.14 ENST00000377873.8
beaded filament structural protein 1
chr1_+_61952036 0.14 ENST00000646453.1
ENST00000635137.1
PATJ crumbs cell polarity complex component
chr19_-_17460804 0.14 ENST00000594663.1
novel protein
chr4_+_54657918 0.14 ENST00000412167.6
ENST00000288135.6
KIT proto-oncogene, receptor tyrosine kinase
chr8_-_18683932 0.14 ENST00000615573.4
pleckstrin and Sec7 domain containing 3
chr17_-_10036741 0.14 ENST00000585266.5
growth arrest specific 7
chr16_+_3654683 0.13 ENST00000246949.10
deoxyribonuclease 1
chr12_-_49900250 0.13 ENST00000552669.5
Fas apoptotic inhibitory molecule 2
chr5_+_140848360 0.13 ENST00000532602.2
protocadherin alpha 9
chr11_-_10808913 0.13 ENST00000527419.6
ENST00000530211.6
ENST00000339995.11
ENST00000530702.2
ENST00000524932.6
ENST00000532570.6
eukaryotic translation initiation factor 4 gamma 2
chr11_+_114060204 0.13 ENST00000683318.1
zinc finger and BTB domain containing 16
chr6_-_3227643 0.13 ENST00000259818.8
tubulin beta 2B class IIb
chr5_-_124745315 0.13 ENST00000306315.9
zinc finger protein 608
chr8_-_18684093 0.13 ENST00000428502.6
pleckstrin and Sec7 domain containing 3
chr1_-_25905989 0.13 ENST00000399728.5
stathmin 1
chr7_+_77538027 0.13 ENST00000433369.6
ENST00000415482.6
protein tyrosine phosphatase non-receptor type 12
chr8_-_18684033 0.12 ENST00000614430.3
pleckstrin and Sec7 domain containing 3
chr12_-_75209422 0.12 ENST00000393288.2
ENST00000540018.5
potassium voltage-gated channel subfamily C member 2
chr9_-_70869076 0.12 ENST00000677594.1
transient receptor potential cation channel subfamily M member 3
chr18_+_13218769 0.12 ENST00000677055.1
ENST00000399848.7
low density lipoprotein receptor class A domain containing 4
chr10_+_21524627 0.12 ENST00000651097.1
MLLT10 histone lysine methyltransferase DOT1L cofactor
chr16_-_15643024 0.12 ENST00000540441.6
meiosis regulator and mRNA stability factor 1
chr19_+_46602050 0.12 ENST00000599839.5
ENST00000596362.1
calmodulin 3
chr22_+_38656627 0.12 ENST00000411557.5
ENST00000396811.6
ENST00000216029.7
ENST00000416285.5
chibby family member 1, beta catenin antagonist
chr3_-_197298558 0.11 ENST00000656944.1
ENST00000346964.6
ENST00000448528.6
ENST00000655488.1
ENST00000357674.9
ENST00000667157.1
ENST00000661336.1
ENST00000654737.1
ENST00000659716.1
ENST00000657381.1
discs large MAGUK scaffold protein 1
chr22_-_38317423 0.11 ENST00000396832.6
ENST00000403904.5
ENST00000405675.7
casein kinase 1 epsilon
chr10_-_29735787 0.11 ENST00000375400.7
supervillin
chr7_-_45088888 0.11 ENST00000490531.3
NAC alpha domain containing
chr12_-_8662619 0.11 ENST00000544889.1
ENST00000543369.5
microfibril associated protein 5
chr3_+_152268920 0.11 ENST00000495875.6
ENST00000324210.10
ENST00000493459.5
muscleblind like splicing regulator 1
chr20_+_35954564 0.11 ENST00000622112.4
ENST00000614708.1
cyclic nucleotide binding domain containing 2
chrX_-_154371210 0.11 ENST00000369856.8
ENST00000422373.6
ENST00000360319.9
filamin A
chr6_-_29559724 0.11 ENST00000377050.5
ubiquitin D
chr10_+_24239181 0.11 ENST00000438429.5
KIAA1217
chr12_+_15322529 0.11 ENST00000348962.7
protein tyrosine phosphatase receptor type O
chr11_-_95910748 0.10 ENST00000675933.1
myotubularin related protein 2
chrX_+_70444827 0.10 ENST00000374360.8
discs large MAGUK scaffold protein 3
chr4_+_26584064 0.10 ENST00000264866.9
ENST00000505206.5
ENST00000511789.5
TBC1 domain family member 19
chr16_-_31073712 0.10 ENST00000414399.1
zinc finger protein 668
chr12_+_22625357 0.10 ENST00000545979.2
ethanolamine kinase 1
chr9_-_86282061 0.10 ENST00000311534.6
iron-sulfur cluster assembly 1
chr11_-_95910824 0.10 ENST00000674528.1
ENST00000675477.1
ENST00000675636.1
myotubularin related protein 2
chr8_-_28386417 0.10 ENST00000521185.5
ENST00000520290.5
ENST00000344423.10
zinc finger protein 395
chr6_-_127518875 0.10 ENST00000465909.2
ENST00000467753.1
SOGA family member 3
chr18_+_48539112 0.10 ENST00000382998.8
cap binding complex dependent translation initiation factor
chr22_-_26618026 0.10 ENST00000647684.1
crystallin beta B1
chr13_-_94479671 0.10 ENST00000377028.10
ENST00000446125.1
dopachrome tautomerase
chrX_+_66164340 0.10 ENST00000441993.7
ENST00000419594.6
ENST00000425114.2
hephaestin
chr1_-_201507116 0.10 ENST00000340006.7
ENST00000526256.5
ENST00000526723.5
ENST00000524951.5
cysteine and glycine rich protein 1
chr1_+_182839338 0.09 ENST00000367549.4
DExH-box helicase 9
chr8_+_24294107 0.09 ENST00000437154.6
ADAM metallopeptidase domain 28
chr12_-_48570046 0.09 ENST00000301046.6
ENST00000549817.1
lactalbumin alpha
chr6_+_30721573 0.09 ENST00000330914.7
tubulin beta class I
chr1_-_25906411 0.09 ENST00000455785.7
stathmin 1
chr17_-_74361860 0.09 ENST00000375366.4
BTB domain containing 17
chr11_-_95910665 0.09 ENST00000674610.1
ENST00000675660.1
myotubularin related protein 2
chr6_-_127519191 0.09 ENST00000525778.5
SOGA family member 3
chr1_+_86424154 0.09 ENST00000370565.5
chloride channel accessory 2
chr3_+_93980130 0.09 ENST00000535334.5
ENST00000681380.1
ENST00000303097.11
ENST00000486562.2
ENST00000471138.5
ENST00000394222.8
ENST00000679872.1
ENST00000679404.1
ENST00000681655.1
ENST00000679657.1
ENST00000679666.1
ADP ribosylation factor like GTPase 13B
chr11_+_196761 0.09 ENST00000325113.9
outer dense fiber of sperm tails 3
chr6_-_118710065 0.09 ENST00000392500.7
ENST00000368488.9
ENST00000434604.5
centrosomal protein 85 like
chrX_+_66164210 0.09 ENST00000343002.7
ENST00000336279.9
hephaestin
chrX_+_130339941 0.09 ENST00000218197.9
solute carrier family 25 member 14
chrX_+_130339886 0.09 ENST00000543953.5
ENST00000612248.4
ENST00000424447.5
ENST00000545805.6
solute carrier family 25 member 14
chr1_+_64470120 0.09 ENST00000651257.2
cache domain containing 1
chr10_-_60572599 0.08 ENST00000503366.5
ankyrin 3
chr5_+_139795795 0.08 ENST00000274710.4
pleckstrin and Sec7 domain containing 2
chrX_-_45200895 0.08 ENST00000377934.4
divergent protein kinase domain 2B
chr17_+_69502397 0.08 ENST00000613873.4
ENST00000589647.5
mitogen-activated protein kinase kinase 6
chr2_+_27583015 0.08 ENST00000379717.5
ENST00000355467.6
ENST00000505973.1
zinc finger protein 512
novel transcript
chr22_-_19524400 0.08 ENST00000618236.2
claudin 5
chr15_+_74318553 0.08 ENST00000558821.5
ENST00000268082.4
coiled-coil domain containing 33
chr10_-_13707536 0.08 ENST00000632570.1
ENST00000477221.2
FERM domain containing 4A
chr1_+_67685170 0.08 ENST00000370985.4
ENST00000370986.9
ENST00000650283.1
ENST00000648742.1
growth arrest and DNA damage inducible alpha
chr2_+_27582969 0.08 ENST00000556601.5
ENST00000413371.6
ENST00000416005.6
zinc finger protein 512
chr14_-_106389858 0.08 ENST00000390617.2
immunoglobulin heavy variable 3-35 (non-functional)
chr1_+_67685342 0.08 ENST00000617962.2
growth arrest and DNA damage inducible alpha
chr3_-_197297523 0.08 ENST00000434148.1
ENST00000412364.2
ENST00000661013.1
ENST00000666007.1
ENST00000422288.6
ENST00000456699.6
ENST00000392380.6
ENST00000670935.1
ENST00000656087.1
ENST00000436682.6
ENST00000662727.1
ENST00000670455.1
ENST00000659221.1
ENST00000671185.1
ENST00000669565.1
ENST00000660898.1
ENST00000667971.1
ENST00000661453.1
discs large MAGUK scaffold protein 1
chr4_+_2818155 0.08 ENST00000511747.6
SH3 domain binding protein 2
chr8_-_42501224 0.08 ENST00000520262.6
ENST00000517366.1
solute carrier family 20 member 2
chr13_-_41019289 0.08 ENST00000239882.7
E74 like ETS transcription factor 1
chr15_+_51751587 0.08 ENST00000539962.6
ENST00000249700.9
tropomodulin 2
chr5_-_177409535 0.08 ENST00000253496.4
coagulation factor XII
chr15_+_81000913 0.08 ENST00000267984.4
talin rod domain containing 1
chr19_-_18606779 0.08 ENST00000684169.1
ENST00000392386.8
cytokine receptor like factor 1
chr8_-_28386073 0.08 ENST00000523095.5
ENST00000522795.1
zinc finger protein 395
chr17_+_77287891 0.08 ENST00000449803.6
ENST00000431235.6
septin 9
chr9_-_127877665 0.08 ENST00000644144.2
adenylate kinase 1
chr12_-_8662808 0.07 ENST00000359478.7
ENST00000396549.6
microfibril associated protein 5
chr22_-_38084093 0.07 ENST00000681075.1
solute carrier family 16 member 8
chr11_+_36296281 0.07 ENST00000530639.6
proline rich 5 like
chr21_+_37073213 0.07 ENST00000418766.5
ENST00000450533.5
ENST00000438055.5
ENST00000355666.5
ENST00000540756.5
ENST00000399010.5
tetratricopeptide repeat domain 3
chr19_+_10602436 0.07 ENST00000590382.5
ENST00000407327.8
solute carrier family 44 member 2
chr14_-_106235582 0.07 ENST00000390607.2
immunoglobulin heavy variable 3-21
chr9_-_127950716 0.07 ENST00000373084.8
family with sequence similarity 102 member A
chr7_-_83162899 0.07 ENST00000423517.6
piccolo presynaptic cytomatrix protein
chr6_+_47698538 0.07 ENST00000327753.7
adhesion G protein-coupled receptor F4
chrX_-_64205680 0.07 ENST00000374869.8
APC membrane recruitment protein 1
chr9_-_127980976 0.07 ENST00000373095.6
family with sequence similarity 102 member A
chr14_-_88554898 0.07 ENST00000556564.6
protein tyrosine phosphatase non-receptor type 21
chr22_+_30764252 0.07 ENST00000445781.5
ENST00000401475.5
oxysterol binding protein 2
chr11_+_73308237 0.06 ENST00000263674.4
Rho guanine nucleotide exchange factor 17
chr1_-_183590439 0.06 ENST00000367535.8
neutrophil cytosolic factor 2
chr16_+_68539737 0.06 ENST00000398253.6
ENST00000573161.1
ZFP90 zinc finger protein
chr10_+_21524670 0.06 ENST00000631589.1
MLLT10 histone lysine methyltransferase DOT1L cofactor
chr1_+_9234748 0.06 ENST00000377403.7
hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase
chr10_+_122163590 0.06 ENST00000368999.5
transforming acidic coiled-coil containing protein 2
chr12_+_22625075 0.06 ENST00000671733.1
ENST00000335148.8
ENST00000672951.1
ENST00000266517.9
ethanolamine kinase 1
chr11_+_394196 0.06 ENST00000331563.7
ENST00000531857.1
plakophilin 3
chr4_+_127781815 0.06 ENST00000508776.5
heat shock protein family A (Hsp70) member 4 like
chr5_+_141359970 0.06 ENST00000522605.2
ENST00000622527.1
protocadherin gamma subfamily B, 2
chr12_-_18738006 0.06 ENST00000266505.12
ENST00000543242.5
ENST00000539072.5
ENST00000541966.5
ENST00000648272.1
phospholipase C zeta 1
chr3_-_71725365 0.06 ENST00000425534.8
eukaryotic translation initiation factor 4E family member 3
chr12_+_11649666 0.06 ENST00000396373.9
ETS variant transcription factor 6
chr14_-_74875998 0.06 ENST00000556489.4
ENST00000673765.1
prospero homeobox 2
chr10_+_68721012 0.06 ENST00000536391.5
ENST00000630771.2
cell division cycle and apoptosis regulator 1
chr13_+_111115303 0.06 ENST00000646102.2
ENST00000449979.5
Rho guanine nucleotide exchange factor 7
chr11_-_79441016 0.06 ENST00000278550.12
teneurin transmembrane protein 4
chrX_+_85244075 0.06 ENST00000276123.7
zinc finger protein 711
chr1_-_21176836 0.05 ENST00000634879.2
ENST00000400422.6
ENST00000602326.5
ENST00000411888.5
ENST00000438975.5
ENST00000374935.7
eukaryotic translation initiation factor 4 gamma 3
chr15_+_75843438 0.05 ENST00000267938.9
ubiquitin conjugating enzyme E2 Q2
chr3_+_183635605 0.05 ENST00000493074.1
ENST00000437402.5
ENST00000454495.6
ENST00000473045.5
ENST00000468101.5
ENST00000427201.2
ENST00000482138.1
ENST00000454652.6
ENST00000242810.11
kelch like family member 24
chr15_-_51751525 0.05 ENST00000454181.6
LysM domain containing 2
chr9_+_130172343 0.05 ENST00000372398.6
neuronal calcium sensor 1
chr4_-_142305935 0.05 ENST00000511838.5
inositol polyphosphate-4-phosphatase type II B
chr17_+_4583998 0.05 ENST00000338859.8
smoothelin like 2
chr18_-_55321640 0.05 ENST00000637169.2
transcription factor 4
chr17_+_77376083 0.05 ENST00000427674.6
septin 9
chr19_-_58519554 0.05 ENST00000354590.7
ENST00000596739.1
zinc finger and BTB domain containing 45
chr16_+_68539213 0.05 ENST00000570495.5
ENST00000564323.5
ENST00000562156.5
ENST00000573685.5
ENST00000563169.7
ENST00000611381.4
ZFP90 zinc finger protein
chr1_-_156859087 0.05 ENST00000368195.4
insulin receptor related receptor
chr2_-_203535253 0.05 ENST00000457812.5
ENST00000319170.10
ENST00000630330.2
ENST00000308091.8
ENST00000453034.5
ENST00000420371.2
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr6_+_32969345 0.05 ENST00000678250.1
bromodomain containing 2
chr8_-_143986425 0.05 ENST00000313059.9
ENST00000524918.5
ENST00000313028.12
ENST00000525773.5
poly(ADP-ribose) polymerase family member 10

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0006683 galactosylceramide catabolic process(GO:0006683)
0.1 0.4 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.3 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.1 0.2 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.1 0.6 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.1 0.2 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.2 GO:0035283 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.2 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.2 GO:0070662 mast cell proliferation(GO:0070662)
0.1 0.2 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.0 0.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.5 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.5 GO:0070307 lens fiber cell development(GO:0070307)
0.0 1.0 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.1 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.1 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.3 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.3 GO:0002934 desmosome organization(GO:0002934)
0.0 0.4 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830)
0.0 0.2 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.2 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.1 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.1 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0051919 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.0 0.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.5 GO:0051290 deoxyribonucleotide biosynthetic process(GO:0009263) protein heterotetramerization(GO:0051290)
0.0 0.0 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.0 0.1 GO:0035549 positive regulation of interferon-beta secretion(GO:0035549)
0.0 0.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.0 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.0 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.2 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0032437 cuticular plate(GO:0032437)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.3 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.5 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0004336 galactosylceramidase activity(GO:0004336)
0.1 0.5 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0 0.2 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.0 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.6 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.1 REACTOME OPSINS Genes involved in Opsins