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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for SPIB

Z-value: 0.81

Motif logo

Transcription factors associated with SPIB

Gene Symbol Gene ID Gene Info
ENSG00000269404.7 SPIB

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SPIBhg38_v1_chr19_+_50418930_504189580.495.4e-03Click!

Activity profile of SPIB motif

Sorted Z-values of SPIB motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SPIB

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_-_50968125 8.54 ENST00000594641.1
kallikrein related peptidase 6
chr1_-_121183911 3.41 ENST00000355228.8
family with sequence similarity 72 member B
chr1_-_206202419 3.22 ENST00000607379.1
ENST00000341209.9
family with sequence similarity 72 member A
chr19_+_35154914 2.92 ENST00000423817.7
FXYD domain containing ion transport regulator 5
chr2_+_113127588 2.56 ENST00000409930.4
interleukin 1 receptor antagonist
chr19_+_48325522 2.56 ENST00000594198.1
ENST00000270221.11
ENST00000597279.5
ENST00000593437.1
epithelial membrane protein 3
chr19_+_53867874 2.45 ENST00000448420.5
ENST00000439000.5
ENST00000391771.1
ENST00000391770.9
myeloid associated differentiation marker
chr11_-_125592448 2.44 ENST00000648911.1
fasciculation and elongation protein zeta 1
chr5_-_39270623 2.39 ENST00000512138.1
ENST00000646045.2
FYN binding protein 1
chr19_+_48325323 2.37 ENST00000596315.5
epithelial membrane protein 3
chr10_-_119542683 2.32 ENST00000369103.3
regulator of G protein signaling 10
chr12_+_15546344 2.25 ENST00000674388.1
ENST00000542557.5
ENST00000445537.6
ENST00000544244.5
ENST00000442921.7
protein tyrosine phosphatase receptor type O
chr22_-_37244417 2.17 ENST00000405484.5
ENST00000441619.5
ENST00000406508.5
Rac family small GTPase 2
chr2_+_233059838 2.12 ENST00000359570.9
inositol polyphosphate-5-phosphatase D
chr2_+_233060295 2.08 ENST00000445964.6
inositol polyphosphate-5-phosphatase D
chr22_-_37244237 2.05 ENST00000401529.3
ENST00000249071.11
Rac family small GTPase 2
chr2_-_207167220 2.04 ENST00000421199.5
ENST00000457962.5
Kruppel like factor 7
chr22_-_37519349 1.92 ENST00000251973.10
caspase recruitment domain family member 10
chr22_-_37519528 1.88 ENST00000403299.5
caspase recruitment domain family member 10
chr19_-_15233432 1.86 ENST00000602233.5
epoxide hydrolase 3
chr3_+_122055355 1.85 ENST00000330540.7
ENST00000469710.5
ENST00000493101.5
CD86 molecule
chr4_-_102345469 1.77 ENST00000356736.5
ENST00000682932.1
solute carrier family 39 member 8
chr12_-_121802886 1.76 ENST00000545885.5
ENST00000542933.5
ENST00000428029.6
ENST00000541694.5
ENST00000536662.5
ENST00000535643.5
ENST00000541657.5
long intergenic non-protein coding RNA 1089
ras homolog family member F, filopodia associated
chr3_+_122077850 1.72 ENST00000482356.5
ENST00000393627.6
CD86 molecule
chr6_-_30684744 1.70 ENST00000615892.4
protein phosphatase 1 regulatory subunit 18
chr16_+_30183595 1.62 ENST00000219150.10
ENST00000570045.5
ENST00000565497.5
ENST00000570244.5
coronin 1A
chr3_+_122077776 1.57 ENST00000264468.9
CD86 molecule
chr1_-_206202827 1.52 ENST00000431655.2
ENST00000367128.8
family with sequence similarity 72 member A
chr1_-_143971965 1.50 ENST00000369175.4
ENST00000584486.6
family with sequence similarity 72 member C
chr1_+_145095967 1.48 ENST00000400889.3
family with sequence similarity 72 member D
chr1_-_121184292 1.46 ENST00000452190.2
ENST00000619376.4
ENST00000369390.7
family with sequence similarity 72 member B
chr4_+_8199363 1.43 ENST00000382521.7
ENST00000457650.7
SH3 domain and tetratricopeptide repeats 1
chr4_+_8199239 1.42 ENST00000245105.8
SH3 domain and tetratricopeptide repeats 1
chr7_+_74773962 1.36 ENST00000289473.10
neutrophil cytosolic factor 1
chrX_-_47629845 1.32 ENST00000469388.1
ENST00000396992.8
ENST00000377005.6
complement factor properdin
chr15_-_34337719 1.22 ENST00000559484.1
ENST00000558589.5
ENST00000458406.6
solute carrier family 12 member 6
chr5_+_160421847 1.17 ENST00000352433.10
ENST00000517480.1
ENST00000520452.5
ENST00000393964.1
PTTG1 regulator of sister chromatid separation, securin
chr7_+_139829242 1.15 ENST00000455353.6
ENST00000458722.6
ENST00000448866.7
ENST00000411653.6
thromboxane A synthase 1
chr6_-_11382247 1.09 ENST00000397378.7
ENST00000513989.5
ENST00000508546.5
ENST00000504387.5
neural precursor cell expressed, developmentally down-regulated 9
chr14_+_85530127 1.09 ENST00000330753.6
fibronectin leucine rich transmembrane protein 2
chr6_-_144064511 1.09 ENST00000626373.2
ENST00000628651.2
ENST00000626294.2
ENST00000437412.5
ENST00000444202.5
ENST00000626462.2
ENST00000627449.2
PLAG1 like zinc finger 1
chr7_+_139829153 1.05 ENST00000652056.1
thromboxane A synthase 1
chr2_-_70553440 1.05 ENST00000450929.5
transforming growth factor alpha
chr5_-_140633690 1.04 ENST00000512545.1
ENST00000401743.6
CD14 molecule
chr15_-_33068143 1.04 ENST00000558197.1
formin 1
chr2_+_173075435 1.02 ENST00000539448.5
mitogen-activated protein kinase kinase kinase 20
chr6_+_130018565 1.02 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL histone methyl-lysine binding protein 3
chr17_-_40937445 0.98 ENST00000436344.7
ENST00000485751.1
keratin 23
chr17_-_38853629 0.97 ENST00000378096.3
ENST00000479035.7
ENST00000394332.5
ENST00000394333.5
ENST00000577407.5
ribosomal protein L23
chr17_-_40937641 0.97 ENST00000209718.8
keratin 23
chr22_+_36913620 0.97 ENST00000403662.8
ENST00000262825.9
colony stimulating factor 2 receptor subunit beta
chr13_+_30735523 0.97 ENST00000380490.5
arachidonate 5-lipoxygenase activating protein
chr2_-_42792558 0.96 ENST00000431905.1
ENST00000294973.11
3-hydroxyanthranilate 3,4-dioxygenase
chr10_-_73096850 0.96 ENST00000307116.6
ENST00000373008.6
ENST00000394890.7
prolyl 4-hydroxylase subunit alpha 1
chr17_-_5234801 0.95 ENST00000571800.5
ENST00000574081.6
ENST00000399600.8
ENST00000574297.1
SLP adaptor and CSK interacting membrane protein
chr1_-_26354080 0.95 ENST00000308182.10
crystallin beta-gamma domain containing 2
chr20_-_47786553 0.91 ENST00000467815.5
ENST00000359930.8
ENST00000484875.5
sulfatase 2
chr17_+_67377272 0.90 ENST00000581322.6
ENST00000299954.13
phosphatidylinositol transfer protein cytoplasmic 1
chr15_-_34337772 0.89 ENST00000354181.8
solute carrier family 12 member 6
chr13_+_30713477 0.88 ENST00000617770.4
arachidonate 5-lipoxygenase activating protein
chr15_-_34336749 0.87 ENST00000397707.6
ENST00000560611.5
solute carrier family 12 member 6
chr1_+_22653228 0.86 ENST00000509305.6
complement C1q B chain
chr2_+_173075714 0.85 ENST00000409176.6
ENST00000338983.7
ENST00000375213.8
mitogen-activated protein kinase kinase kinase 20
chr3_+_98763331 0.85 ENST00000485391.5
ENST00000492254.5
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr10_-_73096974 0.85 ENST00000440381.5
ENST00000263556.3
prolyl 4-hydroxylase subunit alpha 1
chr5_-_173328407 0.84 ENST00000265087.9
stanniocalcin 2
chr6_+_31158518 0.84 ENST00000376255.4
ENST00000376257.8
transcription factor 19
chr17_+_67377413 0.84 ENST00000580974.5
phosphatidylinositol transfer protein cytoplasmic 1
chr10_+_104268852 0.83 ENST00000450629.6
glutathione S-transferase omega 2
chr16_+_71358713 0.80 ENST00000349553.9
ENST00000302628.9
ENST00000562305.5
calbindin 2
chr19_+_45469841 0.79 ENST00000592811.5
ENST00000586615.5
FosB proto-oncogene, AP-1 transcription factor subunit
chr16_+_28878480 0.78 ENST00000395503.9
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr2_-_70553638 0.76 ENST00000444975.5
ENST00000445399.5
ENST00000295400.11
ENST00000418333.6
transforming growth factor alpha
chr6_-_41286665 0.76 ENST00000589614.5
ENST00000244709.9
ENST00000334475.10
ENST00000591620.1
triggering receptor expressed on myeloid cells 1
chr12_+_49323236 0.76 ENST00000549275.5
ENST00000551245.5
ENST00000380327.9
ENST00000548311.5
ENST00000257909.8
ENST00000550346.5
ENST00000550709.5
ENST00000549534.1
ENST00000547807.5
ENST00000551567.1
trophinin associated protein
chr4_+_85604146 0.76 ENST00000512201.5
Rho GTPase activating protein 24
chr3_-_197297523 0.75 ENST00000434148.1
ENST00000412364.2
ENST00000661013.1
ENST00000666007.1
ENST00000422288.6
ENST00000456699.6
ENST00000392380.6
ENST00000670935.1
ENST00000656087.1
ENST00000436682.6
ENST00000662727.1
ENST00000670455.1
ENST00000659221.1
ENST00000671185.1
ENST00000669565.1
ENST00000660898.1
ENST00000667971.1
ENST00000661453.1
discs large MAGUK scaffold protein 1
chr15_-_34318761 0.75 ENST00000290209.9
solute carrier family 12 member 6
chr5_+_96743536 0.75 ENST00000515663.5
calpastatin
chr6_+_26251607 0.75 ENST00000619466.2
H2B clustered histone 9
chr12_+_8950036 0.75 ENST00000539240.5
killer cell lectin like receptor G1
chr20_+_59163810 0.74 ENST00000371030.4
zinc finger protein 831
chr6_-_132757883 0.74 ENST00000525289.5
ENST00000326499.11
vanin 2
chr3_-_151329539 0.74 ENST00000325602.6
purinergic receptor P2Y13
chr1_-_46604283 0.74 ENST00000341183.9
ENST00000649800.1
ENST00000650026.1
ENST00000650508.1
ENST00000496619.6
MAPK interacting serine/threonine kinase 1
chr9_-_112333562 0.72 ENST00000343327.6
polypyrimidine tract binding protein 3
chr11_-_64778747 0.72 ENST00000227503.13
ENST00000377394.7
ENST00000334944.9
splicing factor 1
chr17_+_82237134 0.71 ENST00000583025.1
solute carrier family 16 member 3
chr12_-_27014300 0.71 ENST00000535819.1
ENST00000543803.5
ENST00000535423.5
ENST00000539741.5
ENST00000343028.9
ENST00000545600.1
ENST00000543088.5
transmembrane 7 superfamily member 3
chr1_-_46604214 0.70 ENST00000371946.9
ENST00000428112.7
ENST00000529170.6
ENST00000371945.10
MAPK interacting serine/threonine kinase 1
chr11_-_3837858 0.70 ENST00000396979.1
ras homolog family member G
chr1_+_159204860 0.69 ENST00000368122.4
ENST00000368121.6
atypical chemokine receptor 1 (Duffy blood group)
chr5_+_169637241 0.68 ENST00000520908.7
dedicator of cytokinesis 2
chr16_+_28878382 0.68 ENST00000357084.7
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr1_+_205504644 0.68 ENST00000429964.7
ENST00000443813.6
cyclin dependent kinase 18
chr11_+_1839602 0.68 ENST00000617947.4
ENST00000252898.11
troponin I2, fast skeletal type
chr12_+_119667859 0.68 ENST00000541640.5
protein kinase AMP-activated non-catalytic subunit beta 1
chr7_-_129952631 0.67 ENST00000473814.6
ENST00000490974.1
ubiquitin conjugating enzyme E2 H
chr10_-_90857983 0.67 ENST00000336152.8
5-hydroxytryptamine receptor 7
chr1_+_209768482 0.66 ENST00000367023.5
TRAF3 interacting protein 3
chr1_+_205504592 0.66 ENST00000506784.5
ENST00000360066.6
cyclin dependent kinase 18
chr1_+_161581339 0.64 ENST00000543859.5
ENST00000611236.1
Fc fragment of IgG receptor IIc (gene/pseudogene)
chr9_-_21995262 0.64 ENST00000494262.5
cyclin dependent kinase inhibitor 2A
chr6_+_15246054 0.63 ENST00000341776.7
jumonji and AT-rich interaction domain containing 2
chr3_-_28348924 0.63 ENST00000414162.5
ENST00000420543.6
5-azacytidine induced 2
chr1_+_3624978 0.63 ENST00000378344.7
ENST00000344579.5
tumor protein p63 regulated 1 like
chr14_+_66824439 0.63 ENST00000555456.1
gephyrin
chr21_-_32813695 0.61 ENST00000479548.2
ENST00000490358.5
chromosome 21 open reading frame 62
chr6_-_47042260 0.61 ENST00000371243.2
adhesion G protein-coupled receptor F1
chr22_-_37484505 0.61 ENST00000442496.1
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr6_+_42984532 0.61 ENST00000394110.7
ENST00000472118.5
ENST00000485511.6
ENST00000461010.5
protein phosphatase 2 regulatory subunit B'delta
chr9_-_21995301 0.59 ENST00000498628.6
cyclin dependent kinase inhibitor 2A
chr19_+_7348930 0.59 ENST00000668164.2
Rho/Rac guanine nucleotide exchange factor 18
chr7_-_36724457 0.59 ENST00000617537.5
ENST00000435386.1
acyloxyacyl hydrolase
chr9_+_109640779 0.58 ENST00000374531.6
PALM2 and AKAP2 fusion
chr7_+_106865474 0.58 ENST00000359195.3
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chr11_+_70398404 0.58 ENST00000346329.7
ENST00000301843.13
ENST00000376561.7
cortactin
chr11_+_1840168 0.57 ENST00000381905.3
troponin I2, fast skeletal type
chr17_-_45410414 0.57 ENST00000532038.5
ENST00000528677.1
Rho GTPase activating protein 27
chr6_-_167157980 0.57 ENST00000366834.2
G protein-coupled receptor 31
chr3_-_179451387 0.57 ENST00000675901.1
ENST00000232564.8
ENST00000674862.1
ENST00000497513.1
G protein subunit beta 4
chrX_-_40735476 0.56 ENST00000324817.6
mediator complex subunit 14
chr3_-_16513643 0.56 ENST00000334133.9
raftlin, lipid raft linker 1
chr16_+_30949054 0.56 ENST00000318663.5
ENST00000566237.1
ENST00000562699.1
ORAI calcium release-activated calcium modulator 3
chrX_+_28587411 0.56 ENST00000378993.6
interleukin 1 receptor accessory protein like 1
chr14_+_85530163 0.56 ENST00000554746.1
fibronectin leucine rich transmembrane protein 2
chr7_-_36724543 0.55 ENST00000612871.4
acyloxyacyl hydrolase
chr5_+_96662046 0.55 ENST00000338252.7
ENST00000508830.5
calpastatin
chr19_+_30372364 0.55 ENST00000355537.4
zinc finger protein 536
chr1_-_156705575 0.55 ENST00000368222.8
cellular retinoic acid binding protein 2
chr1_+_40040219 0.55 ENST00000372797.7
ENST00000372802.5
ENST00000449311.5
cyclase associated actin cytoskeleton regulatory protein 1
chrX_-_75156272 0.54 ENST00000620875.5
ENST00000669573.1
ENST00000339447.8
ENST00000645829.3
ENST00000529949.5
ENST00000373394.8
ENST00000253577.9
ENST00000644766.1
ENST00000534524.5
ATP binding cassette subfamily B member 7
chr6_+_116461364 0.54 ENST00000368606.7
ENST00000368605.3
calcium homeostasis modulator family member 6
chr6_-_32178080 0.54 ENST00000336984.6
1-acylglycerol-3-phosphate O-acyltransferase 1
chr2_-_187554351 0.53 ENST00000437725.5
ENST00000409676.5
ENST00000233156.9
ENST00000339091.8
ENST00000420747.1
tissue factor pathway inhibitor
chr12_-_7503841 0.53 ENST00000359156.8
CD163 molecule
chr3_-_28348629 0.53 ENST00000334100.10
5-azacytidine induced 2
chr1_-_160646958 0.53 ENST00000538290.2
signaling lymphocytic activation molecule family member 1
chr11_+_73292755 0.53 ENST00000680955.1
ENST00000538328.2
pyrimidinergic receptor P2Y6
chr7_-_129952901 0.52 ENST00000472396.5
ENST00000355621.8
ubiquitin conjugating enzyme E2 H
chr19_+_17747737 0.51 ENST00000600676.5
ENST00000600209.5
ENST00000596309.5
ENST00000598539.5
ENST00000597474.5
ENST00000593385.5
ENST00000598067.5
ENST00000593833.5
FCH and mu domain containing endocytic adaptor 1
chr16_+_89948697 0.51 ENST00000567999.5
ENST00000610455.4
ENST00000617948.4
ENST00000566079.5
ENST00000566820.5
ENST00000562578.5
ENST00000563594.6
ENST00000561741.5
ENST00000268676.11
ENST00000562986.5
ENST00000569453.5
ENST00000567884.5
ENST00000569061.5
ENST00000418391.6
ENST00000561959.5
ENST00000567874.5
ENST00000570182.5
ENST00000563795.1
differentially expressed in FDCP 8 homolog
chr11_-_64803152 0.51 ENST00000439069.5
ENST00000294066.7
ENST00000377350.7
mitogen-activated protein kinase kinase kinase kinase 2
chr22_+_19760714 0.51 ENST00000649276.2
T-box transcription factor 1
chr3_-_52239082 0.49 ENST00000499914.2
ENST00000678838.1
ENST00000305533.10
ENST00000678330.1
twinfilin actin binding protein 2
chr22_-_40463411 0.49 ENST00000402630.5
ENST00000407029.7
myocardin related transcription factor A
chr13_-_35476682 0.48 ENST00000379919.6
mab-21 like 1
chr19_-_41688258 0.48 ENST00000401731.6
ENST00000006724.7
CEA cell adhesion molecule 7
chr1_-_159923717 0.48 ENST00000368096.5
transgelin 2
chr5_-_156963222 0.48 ENST00000407087.4
ENST00000274532.7
T cell immunoglobulin and mucin domain containing 4
chr9_+_132978651 0.47 ENST00000636137.1
growth factor independent 1B transcriptional repressor
chr12_+_9971402 0.47 ENST00000304361.9
ENST00000396507.7
ENST00000434319.6
C-type lectin domain family 12 member A
chr8_+_27774566 0.46 ENST00000519637.1
establishment of sister chromatid cohesion N-acetyltransferase 2
chr9_-_96383675 0.46 ENST00000375257.2
ENST00000375259.9
ENST00000253270.13
solute carrier family 35 member D2
chr7_+_106865263 0.46 ENST00000440650.6
ENST00000496166.6
ENST00000473541.5
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chr15_-_34337462 0.46 ENST00000676379.1
solute carrier family 12 member 6
chr1_+_15476099 0.45 ENST00000375910.8
chymotrypsin like elastase 2B
chr5_+_58491427 0.45 ENST00000396776.6
ENST00000502276.6
ENST00000511930.2
GRB2 binding adaptor protein, transmembrane
chr17_-_56914032 0.45 ENST00000537230.3
ENST00000316881.9
tripartite motif containing 25
chr1_+_50109817 0.45 ENST00000652353.1
ENST00000371821.6
ENST00000652274.1
ELAV like RNA binding protein 4
chr5_+_58491451 0.45 ENST00000513924.2
ENST00000515443.2
GRB2 binding adaptor protein, transmembrane
chr1_+_161663147 0.45 ENST00000236937.13
ENST00000367961.8
ENST00000358671.9
Fc fragment of IgG receptor IIb
chr11_+_131370478 0.45 ENST00000374791.7
ENST00000683400.1
ENST00000436745.5
neurotrimin
chr17_-_3398410 0.44 ENST00000322608.2
olfactory receptor family 1 subfamily E member 1
chr3_-_28348805 0.44 ENST00000457172.5
ENST00000479665.6
5-azacytidine induced 2
chr19_-_3786254 0.44 ENST00000585778.5
megakaryocyte-associated tyrosine kinase
chr19_-_41688167 0.43 ENST00000602225.1
CEA cell adhesion molecule 7
chr7_-_36724380 0.43 ENST00000617267.4
acyloxyacyl hydrolase
chr1_-_110963897 0.43 ENST00000369763.5
ligand dependent nuclear receptor interacting factor 1
chr1_+_15456727 0.43 ENST00000359621.5
chymotrypsin like elastase 2A
chr4_-_47914569 0.43 ENST00000507489.2
nuclear transcription factor, X-box binding like 1
chr9_+_124862098 0.43 ENST00000353214.6
actin related protein 2/3 complex subunit 5 like
chr19_+_16143678 0.42 ENST00000613986.4
ENST00000593031.1
hematopoietic SH2 domain containing
chr3_-_177196451 0.42 ENST00000430069.5
ENST00000630796.2
ENST00000428970.5
TBL1X receptor 1
chr5_+_10250216 0.42 ENST00000515390.5
chaperonin containing TCP1 subunit 5
chr10_-_96271508 0.42 ENST00000427367.6
ENST00000413476.6
ENST00000371176.6
B cell linker
chr10_-_96271553 0.42 ENST00000224337.10
B cell linker
chr1_-_110963936 0.41 ENST00000485275.2
ligand dependent nuclear receptor interacting factor 1
chr9_-_92878018 0.41 ENST00000332591.6
ENST00000375495.8
ENST00000395505.6
ENST00000395506.7
zinc finger protein 484
chr6_+_124983356 0.40 ENST00000519799.5
ENST00000368414.6
ENST00000359704.2
ring finger protein 217
chr1_-_175192769 0.40 ENST00000423313.6
KIAA0040
chr13_+_30427950 0.40 ENST00000436446.1
ubiquitin conjugating enzyme E2 L5
chr6_+_31586269 0.40 ENST00000438075.7
leukocyte specific transcript 1
chr1_+_46247731 0.40 ENST00000371975.9
ENST00000469835.6
RAD54 like
chrX_+_80335504 0.40 ENST00000538312.5
terminal nucleotidyltransferase 5D
chr14_-_44961889 0.40 ENST00000579157.1
ENST00000396128.9
ENST00000556500.1
kelch like family member 28
chr9_-_112333603 0.40 ENST00000450374.1
ENST00000374257.6
ENST00000374255.6
ENST00000334318.10
polypyrimidine tract binding protein 3
chr3_-_116444983 0.40 ENST00000333617.8
limbic system associated membrane protein
chr22_+_17628828 0.39 ENST00000399782.5
BCL2 like 13
chr11_-_59212869 0.39 ENST00000361050.4
macrophage expressed 1
chr2_-_70835808 0.39 ENST00000410009.5
CD207 molecule
chr9_-_35618367 0.39 ENST00000378431.5
ENST00000378430.3
ENST00000259633.9
CD72 molecule
chr1_+_161707205 0.38 ENST00000367957.7
Fc receptor like A
chr1_+_161707222 0.38 ENST00000236938.12
Fc receptor like A
chr3_-_9792691 0.38 ENST00000343450.2
transcriptional adaptor 3
chr1_+_151198536 0.38 ENST00000349792.9
ENST00000409426.5
ENST00000368888.9
ENST00000441902.6
ENST00000368890.8
ENST00000424999.1
phosphatidylinositol-4-phosphate 5-kinase type 1 alpha
chr1_+_46247684 0.38 ENST00000463715.5
ENST00000442598.5
ENST00000493985.5
ENST00000671528.1
RAD54 like
chr16_+_25691953 0.38 ENST00000331351.6
heparan sulfate-glucosamine 3-sulfotransferase 4
chr10_-_931624 0.38 ENST00000406525.6
La ribonucleoprotein 4B
chr11_-_65121780 0.38 ENST00000525297.5
ENST00000529259.1
FAU ubiquitin like and ribosomal protein S30 fusion

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0002668 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
1.0 4.2 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
1.0 2.9 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.8 2.5 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.6 4.2 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.6 2.3 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.5 1.5 GO:0031443 regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443) relaxation of skeletal muscle(GO:0090076)
0.4 8.5 GO:0016540 protein autoprocessing(GO:0016540)
0.4 4.2 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.3 1.0 GO:0038156 interleukin-3-mediated signaling pathway(GO:0038156)
0.3 2.6 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.3 1.6 GO:0044565 dendritic cell proliferation(GO:0044565)
0.3 1.5 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.3 0.9 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.3 1.6 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.2 1.0 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.2 0.6 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.2 1.0 GO:0071727 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.2 1.0 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.2 0.9 GO:0072092 ureteric bud invasion(GO:0072092)
0.2 1.6 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.2 4.9 GO:0032060 bleb assembly(GO:0032060)
0.2 3.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.2 1.8 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.2 2.4 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.2 1.0 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897) secretory granule localization(GO:0032252)
0.2 0.5 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.2 3.8 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.2 0.8 GO:0034421 post-translational protein acetylation(GO:0034421)
0.2 2.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.2 0.5 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.2 1.8 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.4 GO:0036071 N-glycan fucosylation(GO:0036071)
0.1 0.4 GO:0001794 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) follicular B cell differentiation(GO:0002316) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
0.1 1.3 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.1 1.8 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 0.4 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.1 0.7 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.1 0.5 GO:0002442 response to molecule of fungal origin(GO:0002238) serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554) cellular response to molecule of fungal origin(GO:0071226)
0.1 1.0 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.1 0.8 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.1 0.4 GO:1901257 negative regulation of interleukin-3 production(GO:0032712) negative regulation of granulocyte colony-stimulating factor production(GO:0071656) negative regulation of macrophage colony-stimulating factor production(GO:1901257)
0.1 0.3 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.3 GO:0071931 positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931)
0.1 2.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 1.0 GO:0009407 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.1 0.7 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 2.3 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 0.9 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.3 GO:0002290 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.1 0.2 GO:0043686 co-translational protein modification(GO:0043686)
0.1 0.3 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 1.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.3 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.1 0.6 GO:1904058 positive regulation of gastric acid secretion(GO:0060454) positive regulation of sensory perception of pain(GO:1904058)
0.1 1.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.8 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 0.3 GO:0036269 swimming behavior(GO:0036269)
0.1 0.6 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 0.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.2 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.3 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.1 0.2 GO:1904580 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.1 1.4 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 0.3 GO:0009996 negative regulation of cell fate specification(GO:0009996)
0.1 0.2 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 0.2 GO:2000793 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276) cell proliferation involved in heart valve development(GO:2000793)
0.1 0.6 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.1 1.1 GO:0060022 hard palate development(GO:0060022)
0.1 0.5 GO:0015886 heme transport(GO:0015886)
0.1 0.5 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.2 GO:0010585 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1 0.7 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 1.3 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1 0.2 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.1 0.2 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.1 0.3 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 0.2 GO:0071673 positive regulation of smooth muscle cell chemotaxis(GO:0071673)
0.1 0.5 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 0.2 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.0 0.2 GO:0038189 vestibulocochlear nerve structural organization(GO:0021649) neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) positive regulation of retinal ganglion cell axon guidance(GO:1902336) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) positive regulation of protein lipidation(GO:1903061)
0.0 0.5 GO:0032532 regulation of microvillus length(GO:0032532)
0.0 0.1 GO:1903973 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.0 0.3 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.2 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.4 GO:0060613 fat pad development(GO:0060613)
0.0 0.5 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.2 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 0.6 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.1 GO:0045588 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.0 0.4 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.0 0.6 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.5 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.1 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.0 0.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797) dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.4 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.1 GO:1903259 exon-exon junction complex disassembly(GO:1903259)
0.0 0.6 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.6 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.3 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.1 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.3 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.6 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.5 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.5 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:1903294 regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.3 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.3 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.2 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.8 GO:0051412 response to corticosterone(GO:0051412)
0.0 0.5 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 2.0 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.1 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.2 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.8 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.2 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.0 0.4 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 1.2 GO:2000816 negative regulation of mitotic sister chromatid separation(GO:2000816)
0.0 1.0 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.1 GO:0099558 maintenance of synapse structure(GO:0099558)
0.0 1.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0060215 primitive hemopoiesis(GO:0060215)
0.0 1.3 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 1.9 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 2.4 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 1.6 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.1 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.3 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.5 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.0 0.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.9 GO:0006953 acute-phase response(GO:0006953)
0.0 1.0 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.2 GO:0048820 hair follicle maturation(GO:0048820)
0.0 0.5 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.3 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.5 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.5 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.4 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.1 GO:0072719 cellular response to cisplatin(GO:0072719)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.8 GO:0032449 CBM complex(GO:0032449)
0.6 1.8 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.3 1.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.2 1.0 GO:0005602 complement component C1 complex(GO:0005602)
0.2 1.4 GO:0032010 phagolysosome(GO:0032010)
0.1 1.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.6 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.5 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 1.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.6 GO:0070847 core mediator complex(GO:0070847)
0.1 0.5 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 0.3 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 1.3 GO:0005861 troponin complex(GO:0005861)
0.1 0.2 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.1 1.8 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.8 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.7 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.4 GO:0097443 sorting endosome(GO:0097443)
0.0 0.3 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.3 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 1.0 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.2 GO:0071159 NF-kappaB complex(GO:0071159)
0.0 0.8 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.5 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 3.4 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.3 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 1.8 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.5 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 1.0 GO:0005921 gap junction(GO:0005921)
0.0 0.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 2.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 4.6 GO:0043197 dendritic spine(GO:0043197)
0.0 0.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 2.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 3.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.7 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.3 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.6 GO:0030686 90S preribosome(GO:0030686)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.7 2.2 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.7 4.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.5 1.6 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.4 1.8 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.3 1.0 GO:0004912 interleukin-3 receptor activity(GO:0004912)
0.3 1.8 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.3 4.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.3 0.8 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.2 0.7 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.2 0.6 GO:0061599 nitrate reductase activity(GO:0008940) molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.2 1.0 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.2 0.7 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.2 0.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 1.7 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 1.0 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.2 1.0 GO:0050610 glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.2 0.6 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.4 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.1 0.6 GO:0001626 nociceptin receptor activity(GO:0001626)
0.1 1.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 1.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.4 GO:0019770 IgG receptor activity(GO:0019770)
0.1 1.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.3 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 0.3 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.1 1.3 GO:0031014 troponin T binding(GO:0031014)
0.1 1.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.5 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 0.5 GO:0039552 RIG-I binding(GO:0039552)
0.1 1.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.9 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.3 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.1 0.7 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 2.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 1.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 1.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.2 GO:0055100 adiponectin binding(GO:0055100)
0.1 4.8 GO:0015026 coreceptor activity(GO:0015026)
0.1 3.8 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 1.6 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.8 GO:0036310 annealing helicase activity(GO:0036310)
0.1 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.7 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.7 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 1.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 1.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 2.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.5 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.2 GO:0005046 KDEL sequence binding(GO:0005046)
0.1 1.0 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 1.0 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.4 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 1.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.5 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 1.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.7 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 1.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.8 GO:0097016 L27 domain binding(GO:0097016)
0.0 1.0 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.6 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.3 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 2.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.5 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 2.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.3 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 1.0 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.6 GO:0005522 profilin binding(GO:0005522)
0.0 9.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.6 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.5 GO:0019841 retinol binding(GO:0019841)
0.0 1.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.5 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 1.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.6 GO:0048038 quinone binding(GO:0048038)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.8 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.1 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 0.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 8.2 GO:0005525 GTP binding(GO:0005525)
0.0 0.8 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 0.4 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.2 GO:0032357 oxidized purine DNA binding(GO:0032357)
0.0 0.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.0 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.4 GO:0005549 odorant binding(GO:0005549)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683) 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.2 9.7 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 6.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 4.3 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 5.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.3 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.7 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.0 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.9 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.5 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 3.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 6.5 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 1.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 2.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 0.8 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 1.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 0.4 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 1.0 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.6 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 1.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 0.2 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 1.4 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 1.0 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.7 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 2.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.7 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 2.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 2.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 1.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.2 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 1.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 2.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 3.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.7 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.4 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.5 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.5 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling