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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
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Results for SPIC
Z-value: 1.54
Motif logo
Transcription factors associated with SPIC
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
SPIC
|
ENSG00000166211.8 | SPIC |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| SPIC | hg38_v1_chr12_+_101475319_101475340 | 0.24 | 1.9e-01 | Click! |
Activity profile of SPIC motif
Sorted Z-values of SPIC motif
Network of associatons between targets according to the STRING database.
First level regulatory network of SPIC
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.6 | 15.4 | GO:0002803 | positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803) |
| 2.5 | 10.0 | GO:0045658 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
| 2.0 | 6.0 | GO:0046136 | positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559) |
| 1.4 | 5.7 | GO:0036058 | filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060) |
| 1.4 | 4.1 | GO:0043016 | negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017) |
| 1.2 | 3.6 | GO:2000537 | regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538) |
| 1.2 | 3.5 | GO:0061502 | early endosome to recycling endosome transport(GO:0061502) |
| 0.9 | 2.6 | GO:0033082 | regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654) |
| 0.8 | 9.1 | GO:0034626 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.8 | 4.1 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
| 0.8 | 3.3 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 0.8 | 2.4 | GO:0007057 | spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195) |
| 0.8 | 2.3 | GO:0015920 | lipopolysaccharide transport(GO:0015920) |
| 0.7 | 4.5 | GO:0071543 | diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
| 0.6 | 2.6 | GO:0036116 | medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535) |
| 0.6 | 1.9 | GO:0033241 | regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283) |
| 0.6 | 6.7 | GO:0060753 | regulation of mast cell chemotaxis(GO:0060753) |
| 0.6 | 4.8 | GO:2001137 | positive regulation of endocytic recycling(GO:2001137) |
| 0.6 | 3.4 | GO:0061143 | alveolar primary septum development(GO:0061143) |
| 0.5 | 3.2 | GO:0046340 | diacylglycerol catabolic process(GO:0046340) |
| 0.5 | 1.5 | GO:0051463 | negative regulation of cortisol secretion(GO:0051463) |
| 0.5 | 4.0 | GO:2000660 | negative regulation of interleukin-1-mediated signaling pathway(GO:2000660) |
| 0.5 | 1.5 | GO:1903926 | signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926) |
| 0.5 | 2.9 | GO:0032468 | Golgi calcium ion homeostasis(GO:0032468) |
| 0.5 | 1.4 | GO:0018012 | N-terminal protein amino acid methylation(GO:0006480) N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573) |
| 0.5 | 0.9 | GO:0046601 | positive regulation of centriole replication(GO:0046601) |
| 0.5 | 1.9 | GO:0010266 | response to vitamin B1(GO:0010266) |
| 0.5 | 4.1 | GO:0060574 | intestinal epithelial cell maturation(GO:0060574) |
| 0.4 | 1.3 | GO:0007525 | somatic muscle development(GO:0007525) |
| 0.4 | 1.8 | GO:0046946 | hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947) |
| 0.4 | 1.8 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
| 0.4 | 8.3 | GO:0016540 | protein autoprocessing(GO:0016540) |
| 0.4 | 1.2 | GO:0038156 | interleukin-3-mediated signaling pathway(GO:0038156) |
| 0.4 | 3.6 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 0.4 | 1.5 | GO:0046203 | spermidine catabolic process(GO:0046203) |
| 0.4 | 1.1 | GO:0018874 | benzoate metabolic process(GO:0018874) |
| 0.4 | 1.1 | GO:1990022 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
| 0.4 | 2.2 | GO:0019918 | peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918) |
| 0.4 | 4.7 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 0.4 | 1.1 | GO:0072429 | response to intra-S DNA damage checkpoint signaling(GO:0072429) |
| 0.3 | 1.4 | GO:1902162 | mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164) |
| 0.3 | 1.0 | GO:1901073 | N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073) |
| 0.3 | 1.7 | GO:0071727 | toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727) |
| 0.3 | 1.3 | GO:0010900 | negative regulation of phosphatidylcholine catabolic process(GO:0010900) |
| 0.3 | 1.3 | GO:1903490 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
| 0.3 | 1.0 | GO:1903991 | regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) |
| 0.3 | 2.0 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
| 0.3 | 1.0 | GO:0032912 | negative regulation of transforming growth factor beta2 production(GO:0032912) negative regulation of hair follicle maturation(GO:0048817) regulation of melanosome transport(GO:1902908) |
| 0.3 | 1.3 | GO:0072717 | cellular response to actinomycin D(GO:0072717) |
| 0.3 | 2.1 | GO:0060298 | positive regulation of sarcomere organization(GO:0060298) |
| 0.3 | 0.9 | GO:1902567 | negative regulation of eosinophil activation(GO:1902567) negative regulation of membrane invagination(GO:1905154) negative regulation of eosinophil migration(GO:2000417) |
| 0.3 | 4.7 | GO:0035878 | nail development(GO:0035878) |
| 0.3 | 0.6 | GO:0002434 | immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) |
| 0.3 | 0.9 | GO:0071848 | corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009) |
| 0.3 | 0.9 | GO:0072579 | molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579) |
| 0.3 | 7.3 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.3 | 0.5 | GO:2000646 | positive regulation of receptor catabolic process(GO:2000646) |
| 0.3 | 2.4 | GO:0007068 | negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070) |
| 0.3 | 0.5 | GO:0032641 | lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109) |
| 0.3 | 1.3 | GO:0042360 | vitamin E metabolic process(GO:0042360) |
| 0.2 | 1.5 | GO:0044034 | negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) |
| 0.2 | 1.7 | GO:0038165 | oncostatin-M-mediated signaling pathway(GO:0038165) |
| 0.2 | 0.2 | GO:0032811 | negative regulation of epinephrine secretion(GO:0032811) |
| 0.2 | 1.1 | GO:0003069 | age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571) |
| 0.2 | 1.4 | GO:0019060 | intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708) |
| 0.2 | 2.9 | GO:2001300 | lipoxin metabolic process(GO:2001300) |
| 0.2 | 0.9 | GO:1904116 | response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117) |
| 0.2 | 0.7 | GO:0006726 | eye pigment biosynthetic process(GO:0006726) synaptic vesicle recycling via endosome(GO:0036466) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) |
| 0.2 | 2.0 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
| 0.2 | 0.9 | GO:0002337 | B-1a B cell differentiation(GO:0002337) |
| 0.2 | 1.3 | GO:0010966 | regulation of phosphate transport(GO:0010966) |
| 0.2 | 1.7 | GO:0001957 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 0.2 | 1.3 | GO:0071051 | polyadenylation-dependent snoRNA 3'-end processing(GO:0071051) |
| 0.2 | 1.5 | GO:0042539 | hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) |
| 0.2 | 1.7 | GO:0002774 | Fc receptor mediated inhibitory signaling pathway(GO:0002774) |
| 0.2 | 0.8 | GO:0017185 | peptidyl-lysine hydroxylation(GO:0017185) |
| 0.2 | 4.2 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.2 | 1.4 | GO:0000727 | double-strand break repair via break-induced replication(GO:0000727) |
| 0.2 | 0.6 | GO:0071931 | positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931) |
| 0.2 | 0.6 | GO:0072308 | negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) |
| 0.2 | 0.9 | GO:1990928 | response to amino acid starvation(GO:1990928) |
| 0.2 | 1.7 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.2 | 0.6 | GO:0036071 | N-glycan fucosylation(GO:0036071) |
| 0.2 | 1.3 | GO:1904431 | positive regulation of t-circle formation(GO:1904431) |
| 0.2 | 0.9 | GO:0072092 | ureteric bud invasion(GO:0072092) |
| 0.2 | 0.5 | GO:0061582 | intestinal epithelial cell migration(GO:0061582) |
| 0.2 | 0.2 | GO:2000157 | regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157) |
| 0.2 | 0.5 | GO:0019413 | acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate biosynthetic process(GO:0019542) |
| 0.2 | 2.8 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
| 0.2 | 2.0 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
| 0.2 | 2.3 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
| 0.2 | 2.8 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 0.2 | 0.5 | GO:1902283 | negative regulation of primary amine oxidase activity(GO:1902283) |
| 0.2 | 0.6 | GO:1990737 | response to manganese-induced endoplasmic reticulum stress(GO:1990737) |
| 0.2 | 0.6 | GO:0060010 | Sertoli cell fate commitment(GO:0060010) |
| 0.2 | 1.1 | GO:0090267 | positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) |
| 0.2 | 1.1 | GO:0006001 | fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) |
| 0.2 | 1.1 | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
| 0.2 | 0.6 | GO:1902963 | regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) |
| 0.2 | 1.4 | GO:0007598 | blood coagulation, extrinsic pathway(GO:0007598) |
| 0.2 | 0.8 | GO:0002775 | antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778) |
| 0.2 | 0.9 | GO:0019086 | late viral transcription(GO:0019086) |
| 0.1 | 2.2 | GO:0019388 | galactose catabolic process(GO:0019388) |
| 0.1 | 4.2 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
| 0.1 | 0.6 | GO:0046671 | negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671) |
| 0.1 | 1.0 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
| 0.1 | 0.8 | GO:0010897 | negative regulation of triglyceride catabolic process(GO:0010897) secretory granule localization(GO:0032252) |
| 0.1 | 0.5 | GO:0036229 | glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803) |
| 0.1 | 0.4 | GO:0039534 | negative regulation of MDA-5 signaling pathway(GO:0039534) |
| 0.1 | 0.5 | GO:0035927 | RNA import into mitochondrion(GO:0035927) |
| 0.1 | 1.6 | GO:0070131 | positive regulation of mitochondrial translation(GO:0070131) |
| 0.1 | 0.8 | GO:0003350 | pulmonary myocardium development(GO:0003350) |
| 0.1 | 0.8 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
| 0.1 | 2.8 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.1 | 0.6 | GO:1900126 | negative regulation of hyaluronan biosynthetic process(GO:1900126) |
| 0.1 | 1.4 | GO:0019885 | antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885) |
| 0.1 | 3.7 | GO:0010592 | positive regulation of lamellipodium assembly(GO:0010592) |
| 0.1 | 4.9 | GO:0008053 | mitochondrial fusion(GO:0008053) |
| 0.1 | 1.8 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.1 | 0.5 | GO:0048627 | myoblast development(GO:0048627) |
| 0.1 | 0.9 | GO:0035879 | plasma membrane lactate transport(GO:0035879) |
| 0.1 | 0.9 | GO:0006616 | SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) |
| 0.1 | 1.0 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 0.1 | 0.3 | GO:0090135 | actin filament branching(GO:0090135) |
| 0.1 | 6.5 | GO:1901998 | toxin transport(GO:1901998) |
| 0.1 | 1.6 | GO:0071397 | cellular response to cholesterol(GO:0071397) |
| 0.1 | 2.0 | GO:0061029 | eyelid development in camera-type eye(GO:0061029) |
| 0.1 | 0.4 | GO:1904381 | Golgi apparatus mannose trimming(GO:1904381) |
| 0.1 | 1.3 | GO:0060700 | regulation of ribonuclease activity(GO:0060700) |
| 0.1 | 4.2 | GO:0000732 | strand displacement(GO:0000732) |
| 0.1 | 0.7 | GO:0006565 | L-serine catabolic process(GO:0006565) |
| 0.1 | 0.5 | GO:0034427 | nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427) |
| 0.1 | 4.5 | GO:0070207 | protein homotrimerization(GO:0070207) |
| 0.1 | 1.0 | GO:0001866 | NK T cell proliferation(GO:0001866) |
| 0.1 | 0.8 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.1 | 0.6 | GO:2000152 | regulation of ubiquitin-specific protease activity(GO:2000152) positive regulation of ubiquitin-specific protease activity(GO:2000158) |
| 0.1 | 0.6 | GO:0010757 | negative regulation of plasminogen activation(GO:0010757) |
| 0.1 | 4.2 | GO:0051482 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482) |
| 0.1 | 1.3 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 0.1 | 2.9 | GO:0097421 | liver regeneration(GO:0097421) |
| 0.1 | 0.7 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
| 0.1 | 2.5 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) |
| 0.1 | 3.4 | GO:0006266 | DNA ligation(GO:0006266) |
| 0.1 | 1.6 | GO:1900112 | regulation of histone H3-K9 trimethylation(GO:1900112) |
| 0.1 | 1.3 | GO:0032494 | response to peptidoglycan(GO:0032494) |
| 0.1 | 0.5 | GO:0006294 | nucleotide-excision repair, preincision complex assembly(GO:0006294) |
| 0.1 | 0.7 | GO:0060373 | regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373) |
| 0.1 | 0.5 | GO:0010886 | positive regulation of cholesterol storage(GO:0010886) |
| 0.1 | 1.9 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
| 0.1 | 0.4 | GO:1902725 | negative regulation of satellite cell differentiation(GO:1902725) |
| 0.1 | 1.0 | GO:0021562 | vestibulocochlear nerve development(GO:0021562) |
| 0.1 | 0.5 | GO:2000416 | regulation of eosinophil migration(GO:2000416) positive regulation of eosinophil migration(GO:2000418) |
| 0.1 | 1.3 | GO:0000469 | cleavage involved in rRNA processing(GO:0000469) |
| 0.1 | 0.3 | GO:1903336 | negative regulation of vacuolar transport(GO:1903336) |
| 0.1 | 1.3 | GO:0006048 | UDP-N-acetylglucosamine biosynthetic process(GO:0006048) |
| 0.1 | 0.9 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.1 | 0.9 | GO:2000535 | regulation of entry of bacterium into host cell(GO:2000535) |
| 0.1 | 1.3 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 0.1 | 1.3 | GO:0003322 | pancreatic A cell development(GO:0003322) |
| 0.1 | 1.3 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.1 | 1.5 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.1 | 2.4 | GO:0000470 | maturation of LSU-rRNA(GO:0000470) |
| 0.1 | 0.7 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 0.1 | 3.1 | GO:0034243 | regulation of transcription elongation from RNA polymerase II promoter(GO:0034243) |
| 0.1 | 0.3 | GO:0071673 | positive regulation of smooth muscle cell chemotaxis(GO:0071673) |
| 0.1 | 1.1 | GO:1902018 | negative regulation of cilium assembly(GO:1902018) |
| 0.1 | 0.3 | GO:2000110 | negative regulation of macrophage apoptotic process(GO:2000110) |
| 0.1 | 0.3 | GO:0050904 | diapedesis(GO:0050904) glomerular endothelium development(GO:0072011) |
| 0.1 | 0.3 | GO:0038060 | nitric oxide-cGMP-mediated signaling pathway(GO:0038060) |
| 0.1 | 1.4 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.1 | 0.1 | GO:0070172 | positive regulation of tooth mineralization(GO:0070172) |
| 0.1 | 0.3 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 0.1 | 0.7 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.1 | 0.3 | GO:0060133 | somatotropin secreting cell development(GO:0060133) |
| 0.1 | 3.1 | GO:0000266 | mitochondrial fission(GO:0000266) |
| 0.1 | 1.1 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.1 | 1.4 | GO:0002230 | positive regulation of defense response to virus by host(GO:0002230) |
| 0.1 | 0.6 | GO:0015886 | heme transport(GO:0015886) |
| 0.1 | 0.1 | GO:0002309 | T cell proliferation involved in immune response(GO:0002309) |
| 0.1 | 0.5 | GO:0045040 | protein import into mitochondrial outer membrane(GO:0045040) |
| 0.1 | 1.3 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
| 0.1 | 0.6 | GO:0003433 | chondrocyte development involved in endochondral bone morphogenesis(GO:0003433) |
| 0.1 | 0.2 | GO:1903978 | negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) regulation of microglial cell activation(GO:1903978) |
| 0.1 | 0.8 | GO:1902222 | L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222) |
| 0.1 | 2.3 | GO:0006308 | DNA catabolic process(GO:0006308) |
| 0.1 | 0.3 | GO:0097242 | beta-amyloid clearance(GO:0097242) |
| 0.1 | 0.8 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.1 | 0.6 | GO:1903944 | regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944) |
| 0.1 | 0.5 | GO:0098881 | exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967) |
| 0.1 | 0.5 | GO:0019375 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.1 | 0.7 | GO:0043562 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.1 | 0.4 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 0.1 | 0.3 | GO:0035022 | positive regulation of Rac protein signal transduction(GO:0035022) |
| 0.1 | 0.2 | GO:0097051 | establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) |
| 0.1 | 1.8 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 0.1 | 1.2 | GO:2000675 | negative regulation of type B pancreatic cell apoptotic process(GO:2000675) |
| 0.1 | 1.4 | GO:0051299 | centrosome separation(GO:0051299) |
| 0.0 | 0.2 | GO:0051182 | coenzyme transport(GO:0051182) |
| 0.0 | 0.2 | GO:0052651 | monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651) |
| 0.0 | 0.8 | GO:0045213 | neurotransmitter receptor metabolic process(GO:0045213) |
| 0.0 | 0.5 | GO:0048311 | mitochondrion distribution(GO:0048311) |
| 0.0 | 0.9 | GO:0070208 | protein heterotrimerization(GO:0070208) |
| 0.0 | 0.4 | GO:0048743 | positive regulation of skeletal muscle fiber development(GO:0048743) |
| 0.0 | 0.3 | GO:0035655 | interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351) |
| 0.0 | 0.8 | GO:0072619 | interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619) |
| 0.0 | 0.7 | GO:0030502 | negative regulation of bone mineralization(GO:0030502) |
| 0.0 | 0.5 | GO:0006657 | CDP-choline pathway(GO:0006657) |
| 0.0 | 0.6 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
| 0.0 | 0.1 | GO:0046338 | phosphatidylethanolamine catabolic process(GO:0046338) |
| 0.0 | 0.5 | GO:0042118 | endothelial cell activation(GO:0042118) |
| 0.0 | 2.3 | GO:0032508 | DNA duplex unwinding(GO:0032508) |
| 0.0 | 0.1 | GO:0002678 | positive regulation of chronic inflammatory response(GO:0002678) |
| 0.0 | 3.9 | GO:0048207 | vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) |
| 0.0 | 0.2 | GO:2000825 | positive regulation of androgen receptor activity(GO:2000825) |
| 0.0 | 0.2 | GO:2000111 | positive regulation of macrophage apoptotic process(GO:2000111) |
| 0.0 | 0.7 | GO:0044130 | negative regulation of growth of symbiont in host(GO:0044130) |
| 0.0 | 1.4 | GO:0051569 | regulation of histone H3-K4 methylation(GO:0051569) |
| 0.0 | 0.3 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
| 0.0 | 0.4 | GO:0070206 | protein trimerization(GO:0070206) |
| 0.0 | 0.8 | GO:0035728 | response to hepatocyte growth factor(GO:0035728) |
| 0.0 | 0.2 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
| 0.0 | 3.3 | GO:0030239 | myofibril assembly(GO:0030239) |
| 0.0 | 1.7 | GO:0060236 | regulation of mitotic spindle organization(GO:0060236) |
| 0.0 | 0.2 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 0.0 | 0.2 | GO:0002329 | pre-B cell differentiation(GO:0002329) |
| 0.0 | 0.5 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 0.0 | 3.3 | GO:0033275 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 0.0 | 2.6 | GO:0043303 | mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303) |
| 0.0 | 0.3 | GO:0046532 | regulation of photoreceptor cell differentiation(GO:0046532) |
| 0.0 | 0.2 | GO:2000393 | negative regulation of lamellipodium morphogenesis(GO:2000393) |
| 0.0 | 0.8 | GO:0002115 | store-operated calcium entry(GO:0002115) |
| 0.0 | 0.3 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
| 0.0 | 0.4 | GO:0032790 | ribosome disassembly(GO:0032790) |
| 0.0 | 1.3 | GO:0031063 | regulation of histone deacetylation(GO:0031063) |
| 0.0 | 0.2 | GO:0015727 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) |
| 0.0 | 0.6 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
| 0.0 | 1.8 | GO:0035036 | sperm-egg recognition(GO:0035036) |
| 0.0 | 1.8 | GO:0060976 | coronary vasculature development(GO:0060976) |
| 0.0 | 0.5 | GO:0051665 | membrane raft localization(GO:0051665) |
| 0.0 | 2.4 | GO:0003254 | regulation of membrane depolarization(GO:0003254) |
| 0.0 | 7.9 | GO:0006338 | chromatin remodeling(GO:0006338) |
| 0.0 | 0.8 | GO:0046716 | muscle cell cellular homeostasis(GO:0046716) |
| 0.0 | 0.4 | GO:0098856 | intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856) |
| 0.0 | 0.5 | GO:0030157 | pancreatic juice secretion(GO:0030157) |
| 0.0 | 0.6 | GO:0070498 | interleukin-1-mediated signaling pathway(GO:0070498) |
| 0.0 | 0.0 | GO:0000466 | maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466) |
| 0.0 | 1.5 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.0 | 1.9 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 0.0 | 0.3 | GO:0016557 | peroxisome membrane biogenesis(GO:0016557) regulation of peroxisome size(GO:0044375) |
| 0.0 | 2.0 | GO:0051496 | positive regulation of stress fiber assembly(GO:0051496) |
| 0.0 | 0.7 | GO:0006853 | carnitine shuttle(GO:0006853) |
| 0.0 | 0.3 | GO:0000055 | ribosomal large subunit export from nucleus(GO:0000055) |
| 0.0 | 0.1 | GO:1904379 | tail-anchored membrane protein insertion into ER membrane(GO:0071816) protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379) |
| 0.0 | 0.2 | GO:0042262 | dGTP catabolic process(GO:0006203) DNA protection(GO:0042262) |
| 0.0 | 1.1 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
| 0.0 | 0.2 | GO:0002933 | lipid hydroxylation(GO:0002933) |
| 0.0 | 0.8 | GO:0060716 | labyrinthine layer blood vessel development(GO:0060716) |
| 0.0 | 1.3 | GO:0001953 | negative regulation of cell-matrix adhesion(GO:0001953) |
| 0.0 | 1.0 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
| 0.0 | 0.5 | GO:0045618 | positive regulation of keratinocyte differentiation(GO:0045618) |
| 0.0 | 2.0 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.0 | 0.2 | GO:0032713 | negative regulation of interleukin-4 production(GO:0032713) |
| 0.0 | 1.2 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
| 0.0 | 0.1 | GO:0032237 | activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341) |
| 0.0 | 0.2 | GO:0097577 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 0.0 | 1.3 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
| 0.0 | 0.4 | GO:0010818 | T cell chemotaxis(GO:0010818) |
| 0.0 | 3.1 | GO:0007030 | Golgi organization(GO:0007030) |
| 0.0 | 0.1 | GO:0030853 | negative regulation of granulocyte differentiation(GO:0030853) |
| 0.0 | 0.1 | GO:0046726 | regulation by virus of viral protein levels in host cell(GO:0046719) positive regulation by virus of viral protein levels in host cell(GO:0046726) |
| 0.0 | 0.4 | GO:0003299 | muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898) |
| 0.0 | 0.6 | GO:0061049 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.0 | 1.3 | GO:0045839 | negative regulation of mitotic nuclear division(GO:0045839) |
| 0.0 | 0.3 | GO:0015866 | ADP transport(GO:0015866) |
| 0.0 | 0.9 | GO:0007271 | synaptic transmission, cholinergic(GO:0007271) |
| 0.0 | 0.5 | GO:0030071 | regulation of mitotic metaphase/anaphase transition(GO:0030071) |
| 0.0 | 0.9 | GO:0035428 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
| 0.0 | 0.1 | GO:0034227 | tRNA thio-modification(GO:0034227) |
| 0.0 | 0.8 | GO:0008334 | histone mRNA metabolic process(GO:0008334) |
| 0.0 | 0.8 | GO:0001893 | maternal placenta development(GO:0001893) |
| 0.0 | 0.3 | GO:2000304 | positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304) |
| 0.0 | 0.0 | GO:0090224 | regulation of spindle organization(GO:0090224) |
| 0.0 | 0.1 | GO:0000451 | rRNA 2'-O-methylation(GO:0000451) |
| 0.0 | 0.2 | GO:0043615 | astrocyte cell migration(GO:0043615) |
| 0.0 | 0.2 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
| 0.0 | 1.8 | GO:0045740 | positive regulation of DNA replication(GO:0045740) |
| 0.0 | 1.9 | GO:0006501 | C-terminal protein lipidation(GO:0006501) |
| 0.0 | 0.2 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 0.0 | 0.1 | GO:0043606 | histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606) |
| 0.0 | 0.2 | GO:2001140 | regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140) |
| 0.0 | 0.1 | GO:1902952 | positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 0.0 | 0.4 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.0 | 0.8 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
| 0.0 | 0.1 | GO:0060125 | negative regulation of growth hormone secretion(GO:0060125) |
| 0.0 | 0.3 | GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
| 0.0 | 0.9 | GO:0035690 | cellular response to drug(GO:0035690) |
| 0.0 | 0.8 | GO:0019985 | translesion synthesis(GO:0019985) |
| 0.0 | 0.4 | GO:0046069 | cGMP catabolic process(GO:0046069) |
| 0.0 | 0.4 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 0.0 | 0.1 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.0 | 0.2 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.0 | 0.3 | GO:0060219 | camera-type eye photoreceptor cell differentiation(GO:0060219) |
| 0.0 | 0.9 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
| 0.0 | 0.2 | GO:0052697 | flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697) |
| 0.0 | 0.1 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
| 0.0 | 0.2 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
| 0.0 | 0.1 | GO:0042904 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
| 0.0 | 0.2 | GO:2000009 | negative regulation of protein localization to cell surface(GO:2000009) |
| 0.0 | 0.3 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
| 0.0 | 0.3 | GO:0007202 | activation of phospholipase C activity(GO:0007202) |
| 0.0 | 0.3 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.0 | 0.4 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) |
| 0.0 | 0.3 | GO:0060134 | prepulse inhibition(GO:0060134) |
| 0.0 | 0.6 | GO:0001824 | blastocyst development(GO:0001824) |
| 0.0 | 1.8 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.0 | 0.8 | GO:0043550 | regulation of lipid kinase activity(GO:0043550) |
| 0.0 | 0.7 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.0 | 0.2 | GO:0006449 | regulation of translational termination(GO:0006449) |
| 0.0 | 0.4 | GO:0043101 | purine-containing compound salvage(GO:0043101) |
| 0.0 | 0.5 | GO:0009435 | NAD biosynthetic process(GO:0009435) |
| 0.0 | 0.3 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
| 0.0 | 0.8 | GO:0006368 | transcription elongation from RNA polymerase II promoter(GO:0006368) |
| 0.0 | 1.1 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.0 | 0.7 | GO:0051289 | protein homotetramerization(GO:0051289) |
| 0.0 | 0.4 | GO:0003091 | renal water homeostasis(GO:0003091) |
| 0.0 | 0.6 | GO:0097484 | dendrite extension(GO:0097484) |
| 0.0 | 0.2 | GO:1901741 | positive regulation of myoblast fusion(GO:1901741) |
| 0.0 | 0.3 | GO:0097320 | membrane tubulation(GO:0097320) |
| 0.0 | 2.0 | GO:0008360 | regulation of cell shape(GO:0008360) |
| 0.0 | 3.4 | GO:0006898 | receptor-mediated endocytosis(GO:0006898) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.2 | 15.4 | GO:0097209 | epidermal lamellar body(GO:0097209) |
| 0.8 | 4.1 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
| 0.8 | 4.8 | GO:0020016 | ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018) |
| 0.8 | 2.4 | GO:0001674 | female germ cell nucleus(GO:0001674) |
| 0.8 | 2.3 | GO:0005674 | transcription factor TFIIF complex(GO:0005674) |
| 0.6 | 1.7 | GO:0005900 | oncostatin-M receptor complex(GO:0005900) |
| 0.5 | 2.2 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
| 0.5 | 3.6 | GO:0042721 | mitochondrial inner membrane protein insertion complex(GO:0042721) |
| 0.5 | 2.5 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
| 0.4 | 2.8 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.4 | 1.5 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
| 0.4 | 1.1 | GO:0055087 | Ski complex(GO:0055087) |
| 0.4 | 1.4 | GO:0005602 | complement component C1 complex(GO:0005602) |
| 0.3 | 1.4 | GO:0000811 | GINS complex(GO:0000811) |
| 0.3 | 9.2 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.3 | 1.5 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 0.3 | 0.9 | GO:1990723 | cytoplasmic periphery of the nuclear pore complex(GO:1990723) |
| 0.3 | 3.3 | GO:0043203 | axon hillock(GO:0043203) |
| 0.3 | 1.5 | GO:0032807 | DNA ligase IV complex(GO:0032807) |
| 0.3 | 7.8 | GO:0031011 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
| 0.3 | 0.9 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.3 | 1.4 | GO:0036502 | Derlin-1-VIMP complex(GO:0036502) |
| 0.3 | 5.6 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.2 | 3.9 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.2 | 1.1 | GO:0048476 | Holliday junction resolvase complex(GO:0048476) |
| 0.2 | 1.5 | GO:0032021 | NELF complex(GO:0032021) |
| 0.2 | 1.5 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.2 | 3.0 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.2 | 2.7 | GO:0032797 | SMN complex(GO:0032797) |
| 0.2 | 0.8 | GO:0005944 | phosphatidylinositol 3-kinase complex, class IB(GO:0005944) |
| 0.2 | 1.3 | GO:0000801 | central element(GO:0000801) |
| 0.2 | 1.8 | GO:0036128 | CatSper complex(GO:0036128) |
| 0.2 | 1.0 | GO:1990357 | terminal web(GO:1990357) |
| 0.2 | 1.7 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.2 | 1.7 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.1 | 1.0 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
| 0.1 | 2.3 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.1 | 4.9 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.1 | 2.2 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.1 | 0.6 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 0.1 | 2.0 | GO:0042555 | MCM complex(GO:0042555) |
| 0.1 | 1.1 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.1 | 4.0 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.1 | 0.7 | GO:0043527 | tRNA methyltransferase complex(GO:0043527) |
| 0.1 | 0.7 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.1 | 1.6 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.1 | 0.9 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
| 0.1 | 3.7 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.1 | 0.5 | GO:1990796 | photoreceptor cell terminal bouton(GO:1990796) |
| 0.1 | 0.8 | GO:0005683 | U7 snRNP(GO:0005683) |
| 0.1 | 1.4 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.1 | 0.9 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.1 | 0.3 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
| 0.1 | 1.3 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 0.1 | 0.9 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 0.1 | 0.8 | GO:0016589 | NURF complex(GO:0016589) |
| 0.1 | 1.0 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.1 | 1.3 | GO:0070938 | contractile ring(GO:0070938) |
| 0.1 | 1.6 | GO:0005861 | troponin complex(GO:0005861) |
| 0.1 | 0.8 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.1 | 0.4 | GO:1902560 | GMP reductase complex(GO:1902560) |
| 0.1 | 2.3 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.1 | 1.4 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.1 | 1.2 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.1 | 0.8 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.1 | 2.4 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.1 | 0.7 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
| 0.1 | 0.5 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 0.1 | 0.7 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.1 | 1.0 | GO:0030897 | HOPS complex(GO:0030897) |
| 0.1 | 3.0 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.1 | 0.7 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 0.1 | 2.9 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.1 | 0.2 | GO:0005965 | protein farnesyltransferase complex(GO:0005965) |
| 0.1 | 1.5 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.1 | 5.0 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.1 | 1.8 | GO:0030867 | rough endoplasmic reticulum membrane(GO:0030867) |
| 0.1 | 0.2 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.1 | 0.5 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 0.1 | 1.4 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.1 | 5.5 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.0 | 5.3 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 1.9 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.0 | 0.4 | GO:0032584 | growth cone membrane(GO:0032584) |
| 0.0 | 3.9 | GO:1903293 | protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293) |
| 0.0 | 0.7 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.0 | 0.7 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.0 | 0.4 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.0 | 0.3 | GO:0001939 | female pronucleus(GO:0001939) male pronucleus(GO:0001940) |
| 0.0 | 0.5 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.0 | 0.4 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.0 | 0.6 | GO:0044232 | organelle membrane contact site(GO:0044232) |
| 0.0 | 0.6 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.0 | 1.3 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.0 | 2.8 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.0 | 0.3 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 0.0 | 0.2 | GO:0005927 | muscle tendon junction(GO:0005927) |
| 0.0 | 0.2 | GO:0043196 | varicosity(GO:0043196) |
| 0.0 | 5.1 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 0.2 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 0.0 | 2.6 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 0.4 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.0 | 0.9 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.0 | 12.7 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 0.6 | GO:0046930 | pore complex(GO:0046930) |
| 0.0 | 0.5 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.0 | 0.3 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.0 | 2.8 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.4 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.0 | 12.0 | GO:0098857 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 0.0 | 6.1 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 0.1 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.0 | 0.1 | GO:0072379 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 0.0 | 0.7 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.0 | 4.3 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 1.7 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 0.7 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.0 | 0.1 | GO:0071942 | XPC complex(GO:0071942) |
| 0.0 | 1.6 | GO:0005902 | microvillus(GO:0005902) |
| 0.0 | 1.0 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.0 | 2.1 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 2.2 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.0 | 0.3 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.0 | 3.0 | GO:0043679 | axon terminus(GO:0043679) |
| 0.0 | 0.1 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.0 | 2.4 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 4.2 | GO:0031968 | organelle outer membrane(GO:0031968) |
| 0.0 | 1.3 | GO:0015030 | Cajal body(GO:0015030) |
| 0.0 | 0.3 | GO:0033391 | chromatoid body(GO:0033391) |
| 0.0 | 0.2 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.0 | 2.1 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.0 | 0.2 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.0 | 0.4 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.0 | 0.2 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 0.0 | 0.2 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.0 | 1.4 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.0 | 0.6 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 1.2 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 1.3 | GO:0005884 | actin filament(GO:0005884) |
| 0.0 | 0.2 | GO:0019774 | proteasome core complex, beta-subunit complex(GO:0019774) |
| 0.0 | 0.0 | GO:0071006 | U2-type catalytic step 1 spliceosome(GO:0071006) |
| 0.0 | 2.8 | GO:0030018 | Z disc(GO:0030018) |
| 0.0 | 0.3 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.0 | 0.1 | GO:0010369 | chromocenter(GO:0010369) |
| 0.0 | 0.1 | GO:0000110 | nucleotide-excision repair factor 1 complex(GO:0000110) |
| 0.0 | 1.3 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 0.3 | GO:0030686 | 90S preribosome(GO:0030686) |
| 0.0 | 0.5 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 0.2 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.0 | 0.5 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
| 0.0 | 0.2 | GO:0043596 | nuclear replication fork(GO:0043596) |
| 0.0 | 0.2 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 0.0 | 0.2 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.0 | 1.6 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 0.8 | GO:0045095 | keratin filament(GO:0045095) |
| 0.0 | 0.8 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.0 | 1.1 | GO:0072562 | blood microparticle(GO:0072562) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 10.0 | GO:0016314 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314) |
| 1.2 | 3.5 | GO:0005150 | interleukin-1, Type I receptor binding(GO:0005150) |
| 1.1 | 3.2 | GO:0033878 | hormone-sensitive lipase activity(GO:0033878) |
| 0.8 | 9.1 | GO:0102336 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.8 | 4.1 | GO:0019912 | cyclin-dependent protein kinase activating kinase activity(GO:0019912) |
| 0.8 | 3.9 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
| 0.8 | 2.3 | GO:0070506 | high-density lipoprotein particle receptor activity(GO:0070506) |
| 0.8 | 3.8 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
| 0.7 | 4.5 | GO:0052845 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848) |
| 0.7 | 2.0 | GO:0055100 | adiponectin binding(GO:0055100) |
| 0.6 | 1.9 | GO:0036487 | nitric-oxide synthase inhibitor activity(GO:0036487) |
| 0.6 | 2.4 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
| 0.6 | 2.9 | GO:0004464 | leukotriene-C4 synthase activity(GO:0004464) |
| 0.6 | 2.2 | GO:0003978 | UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978) |
| 0.5 | 1.4 | GO:0071885 | N-terminal protein N-methyltransferase activity(GO:0071885) |
| 0.5 | 3.3 | GO:1904288 | BAT3 complex binding(GO:1904288) |
| 0.5 | 2.7 | GO:0004966 | galanin receptor activity(GO:0004966) |
| 0.5 | 1.4 | GO:0004421 | hydroxymethylglutaryl-CoA synthase activity(GO:0004421) |
| 0.4 | 1.8 | GO:0008475 | procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) |
| 0.4 | 1.3 | GO:0016419 | [acyl-carrier-protein] S-malonyltransferase activity(GO:0004314) 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420) |
| 0.4 | 3.3 | GO:0051373 | FATZ binding(GO:0051373) |
| 0.4 | 1.2 | GO:0004912 | interleukin-3 receptor activity(GO:0004912) |
| 0.4 | 2.4 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 0.4 | 5.6 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
| 0.4 | 2.2 | GO:0035243 | protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) |
| 0.4 | 1.4 | GO:0061769 | ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769) |
| 0.4 | 3.9 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.3 | 1.0 | GO:0003863 | alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863) |
| 0.3 | 6.0 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.3 | 2.0 | GO:0045029 | UDP-activated nucleotide receptor activity(GO:0045029) |
| 0.3 | 6.8 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.3 | 0.3 | GO:0001129 | RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132) |
| 0.3 | 2.2 | GO:0015333 | peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897) |
| 0.3 | 2.1 | GO:0043141 | ATP-dependent 5'-3' DNA helicase activity(GO:0043141) |
| 0.3 | 5.5 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.3 | 2.6 | GO:0036042 | long-chain fatty acyl-CoA binding(GO:0036042) |
| 0.3 | 0.9 | GO:0061599 | nitrate reductase activity(GO:0008940) molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599) |
| 0.3 | 1.7 | GO:0016019 | peptidoglycan receptor activity(GO:0016019) |
| 0.3 | 1.4 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
| 0.3 | 1.7 | GO:0004924 | oncostatin-M receptor activity(GO:0004924) |
| 0.3 | 1.9 | GO:0005497 | androgen binding(GO:0005497) |
| 0.3 | 0.8 | GO:0001716 | L-amino-acid oxidase activity(GO:0001716) |
| 0.3 | 0.8 | GO:0047012 | C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity(GO:0047012) |
| 0.3 | 1.0 | GO:0042282 | hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282) |
| 0.3 | 1.3 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 0.2 | 1.7 | GO:0000293 | ferric-chelate reductase activity(GO:0000293) |
| 0.2 | 0.7 | GO:0003941 | L-serine ammonia-lyase activity(GO:0003941) |
| 0.2 | 2.3 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
| 0.2 | 1.3 | GO:0004366 | glycerol-3-phosphate O-acyltransferase activity(GO:0004366) |
| 0.2 | 0.9 | GO:0031726 | CCR1 chemokine receptor binding(GO:0031726) |
| 0.2 | 1.5 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
| 0.2 | 2.5 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
| 0.2 | 5.9 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.2 | 1.7 | GO:0032396 | inhibitory MHC class I receptor activity(GO:0032396) |
| 0.2 | 2.2 | GO:0030621 | U4 snRNA binding(GO:0030621) |
| 0.2 | 1.7 | GO:0043426 | MRF binding(GO:0043426) |
| 0.2 | 0.6 | GO:0046921 | glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921) |
| 0.2 | 0.5 | GO:0031753 | endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755) |
| 0.2 | 0.9 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.2 | 0.5 | GO:0033749 | histone demethylase activity (H3-R2 specific)(GO:0033746) histone demethylase activity (H4-R3 specific)(GO:0033749) |
| 0.2 | 2.0 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.2 | 2.3 | GO:0019211 | phosphatase activator activity(GO:0019211) |
| 0.2 | 6.6 | GO:0017147 | Wnt-protein binding(GO:0017147) |
| 0.2 | 0.8 | GO:0071208 | histone pre-mRNA DCP binding(GO:0071208) |
| 0.2 | 1.4 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.2 | 1.1 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.2 | 0.5 | GO:0033699 | DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699) |
| 0.2 | 0.6 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
| 0.1 | 0.7 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 0.1 | 3.1 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.1 | 0.6 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 0.1 | 0.9 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
| 0.1 | 0.4 | GO:0004772 | sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736) |
| 0.1 | 1.2 | GO:0031433 | telethonin binding(GO:0031433) |
| 0.1 | 1.3 | GO:0070569 | uridylyltransferase activity(GO:0070569) |
| 0.1 | 0.7 | GO:0003896 | DNA primase activity(GO:0003896) |
| 0.1 | 0.5 | GO:0003943 | N-acetylgalactosamine-4-sulfatase activity(GO:0003943) |
| 0.1 | 2.5 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.1 | 1.4 | GO:0047760 | butyrate-CoA ligase activity(GO:0047760) |
| 0.1 | 0.5 | GO:0003987 | acetate-CoA ligase activity(GO:0003987) |
| 0.1 | 0.3 | GO:0016230 | sphingomyelin phosphodiesterase activator activity(GO:0016230) |
| 0.1 | 1.8 | GO:0008381 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
| 0.1 | 0.5 | GO:0052596 | tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596) |
| 0.1 | 0.5 | GO:0032089 | NACHT domain binding(GO:0032089) |
| 0.1 | 1.3 | GO:0060228 | phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228) |
| 0.1 | 1.0 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 0.1 | 1.6 | GO:0031014 | troponin T binding(GO:0031014) |
| 0.1 | 1.2 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 0.1 | 1.1 | GO:0016721 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 0.1 | 0.9 | GO:0005047 | signal recognition particle binding(GO:0005047) |
| 0.1 | 1.8 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.1 | 0.6 | GO:0004910 | interleukin-1, Type II, blocking receptor activity(GO:0004910) |
| 0.1 | 0.8 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 0.1 | 1.8 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.1 | 1.5 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.1 | 0.7 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
| 0.1 | 2.4 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.1 | 0.5 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
| 0.1 | 3.4 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.1 | 1.4 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.1 | 1.6 | GO:0001730 | 2'-5'-oligoadenylate synthetase activity(GO:0001730) |
| 0.1 | 0.3 | GO:0005148 | prolactin receptor binding(GO:0005148) |
| 0.1 | 2.6 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.1 | 0.3 | GO:0001034 | RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034) |
| 0.1 | 0.6 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 0.1 | 2.9 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.1 | 0.5 | GO:0031728 | CCR3 chemokine receptor binding(GO:0031728) |
| 0.1 | 1.5 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.1 | 0.3 | GO:0042008 | interleukin-18 receptor activity(GO:0042008) |
| 0.1 | 1.1 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.1 | 0.5 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.1 | 1.1 | GO:0004985 | opioid receptor activity(GO:0004985) |
| 0.1 | 0.9 | GO:0004064 | arylesterase activity(GO:0004064) |
| 0.1 | 0.8 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.1 | 1.5 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 0.1 | 1.0 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
| 0.1 | 0.7 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 0.1 | 0.9 | GO:0043855 | intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855) |
| 0.1 | 0.6 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.1 | 2.4 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.1 | 0.6 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.1 | 3.0 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.1 | 0.4 | GO:0016657 | GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657) |
| 0.1 | 1.0 | GO:0022820 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.1 | 0.7 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
| 0.1 | 3.6 | GO:0051183 | vitamin transporter activity(GO:0051183) |
| 0.1 | 0.4 | GO:0004663 | Rab geranylgeranyltransferase activity(GO:0004663) |
| 0.1 | 2.3 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.1 | 22.8 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.1 | 0.3 | GO:0004949 | cannabinoid receptor activity(GO:0004949) |
| 0.1 | 0.8 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.1 | 0.8 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.1 | 0.4 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) |
| 0.1 | 0.5 | GO:0015186 | L-glutamine transmembrane transporter activity(GO:0015186) |
| 0.1 | 3.4 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.1 | 0.5 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
| 0.1 | 1.0 | GO:0019957 | C-C chemokine binding(GO:0019957) |
| 0.1 | 0.9 | GO:0043138 | 3'-5' DNA helicase activity(GO:0043138) |
| 0.1 | 1.2 | GO:0005522 | profilin binding(GO:0005522) |
| 0.1 | 0.6 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
| 0.1 | 1.2 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.1 | 2.6 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.1 | 0.2 | GO:0008413 | 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539) |
| 0.1 | 0.2 | GO:0015057 | thrombin receptor activity(GO:0015057) |
| 0.1 | 0.2 | GO:0051431 | corticotropin-releasing hormone receptor 2 binding(GO:0051431) |
| 0.1 | 0.6 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.1 | 1.2 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.1 | 0.9 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
| 0.1 | 1.6 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.1 | 1.1 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.1 | 0.9 | GO:0016423 | tRNA (guanine) methyltransferase activity(GO:0016423) |
| 0.1 | 0.3 | GO:0016520 | growth hormone-releasing hormone receptor activity(GO:0016520) |
| 0.1 | 0.8 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.0 | 0.6 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.0 | 0.4 | GO:0010340 | carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998) |
| 0.0 | 0.6 | GO:0019864 | IgG binding(GO:0019864) |
| 0.0 | 2.6 | GO:0015026 | coreceptor activity(GO:0015026) |
| 0.0 | 3.2 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.0 | 1.4 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 0.4 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.0 | 0.1 | GO:0070039 | rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039) |
| 0.0 | 0.1 | GO:0033754 | indoleamine 2,3-dioxygenase activity(GO:0033754) |
| 0.0 | 0.3 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 0.0 | 4.1 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.0 | 1.5 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 0.8 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
| 0.0 | 0.7 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.0 | 0.2 | GO:0034875 | oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875) |
| 0.0 | 0.6 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.0 | 0.4 | GO:0089720 | caspase binding(GO:0089720) |
| 0.0 | 0.2 | GO:0070051 | fibrinogen binding(GO:0070051) |
| 0.0 | 1.0 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 1.1 | GO:0005549 | odorant binding(GO:0005549) |
| 0.0 | 0.7 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 4.7 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
| 0.0 | 0.8 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.0 | 0.6 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.0 | 0.4 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.0 | 0.6 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) transmembrane receptor protein tyrosine kinase activator activity(GO:0030297) |
| 0.0 | 0.7 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.0 | 0.9 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
| 0.0 | 0.4 | GO:0004118 | cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) |
| 0.0 | 0.2 | GO:0031544 | peptidyl-proline 3-dioxygenase activity(GO:0031544) |
| 0.0 | 1.2 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 0.8 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.0 | 0.5 | GO:0004950 | G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950) |
| 0.0 | 0.1 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
| 0.0 | 0.1 | GO:0001007 | transcription factor activity, RNA polymerase III transcription factor binding(GO:0001007) |
| 0.0 | 0.9 | GO:0005355 | glucose transmembrane transporter activity(GO:0005355) |
| 0.0 | 0.4 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.0 | 0.3 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.0 | 2.4 | GO:0004536 | deoxyribonuclease activity(GO:0004536) |
| 0.0 | 0.2 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
| 0.0 | 1.5 | GO:0043022 | ribosome binding(GO:0043022) |
| 0.0 | 0.4 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.0 | 1.0 | GO:0019200 | carbohydrate kinase activity(GO:0019200) |
| 0.0 | 0.5 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.0 | 1.3 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 0.4 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 0.2 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
| 0.0 | 0.8 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.0 | 0.3 | GO:0005347 | ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217) |
| 0.0 | 0.5 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
| 0.0 | 10.5 | GO:0005525 | GTP binding(GO:0005525) |
| 0.0 | 1.2 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.0 | 0.2 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 0.0 | 0.2 | GO:0004983 | neuropeptide Y receptor activity(GO:0004983) |
| 0.0 | 0.2 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.0 | 0.6 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.0 | 0.1 | GO:0004522 | ribonuclease A activity(GO:0004522) |
| 0.0 | 0.1 | GO:0038051 | glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
| 0.0 | 1.0 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.0 | 0.5 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617) |
| 0.0 | 1.2 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 0.8 | GO:0016303 | 1-phosphatidylinositol-3-kinase activity(GO:0016303) |
| 0.0 | 0.3 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 0.0 | 0.2 | GO:0008199 | ferric iron binding(GO:0008199) |
| 0.0 | 0.1 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
| 0.0 | 0.1 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.0 | 0.2 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.0 | 0.3 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.0 | 0.3 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.0 | 0.4 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.0 | 0.6 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
| 0.0 | 0.0 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
| 0.0 | 0.6 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
| 0.0 | 0.1 | GO:0003691 | double-stranded telomeric DNA binding(GO:0003691) |
| 0.0 | 0.6 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.0 | 2.6 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.0 | 0.2 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.0 | 0.1 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) |
| 0.0 | 0.2 | GO:0043295 | glutathione binding(GO:0043295) |
| 0.0 | 2.2 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.0 | 0.7 | GO:0004714 | transmembrane receptor protein tyrosine kinase activity(GO:0004714) |
| 0.0 | 0.2 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 15.4 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.3 | 4.6 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.3 | 15.0 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.2 | 12.6 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.2 | 8.5 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.2 | 8.2 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.1 | 2.8 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.1 | 5.0 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.1 | 0.4 | PID CXCR3 PATHWAY | CXCR3-mediated signaling events |
| 0.1 | 2.9 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.1 | 5.9 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.1 | 1.1 | PID CXCR4 PATHWAY | CXCR4-mediated signaling events |
| 0.1 | 7.5 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.1 | 4.3 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
| 0.1 | 4.3 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.1 | 1.5 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.1 | 1.9 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.1 | 3.4 | PID MYC PATHWAY | C-MYC pathway |
| 0.1 | 4.0 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.1 | 1.9 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.1 | 0.3 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.1 | 0.9 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.1 | 1.2 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.1 | 1.1 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.1 | 4.5 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.1 | 3.2 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.1 | 1.9 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.0 | 1.8 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.0 | 1.5 | PID TCPTP PATHWAY | Signaling events mediated by TCPTP |
| 0.0 | 1.9 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 0.8 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.0 | 2.0 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.0 | 1.8 | PID CDC42 PATHWAY | CDC42 signaling events |
| 0.0 | 0.5 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.0 | 0.6 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 1.9 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 2.6 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 0.5 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.0 | 0.9 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.0 | 0.5 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 0.5 | PID ATR PATHWAY | ATR signaling pathway |
| 0.0 | 1.4 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.5 | PID INTEGRIN1 PATHWAY | Beta1 integrin cell surface interactions |
| 0.0 | 0.5 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 0.0 | 0.3 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 0.0 | 0.4 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.0 | 0.4 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.0 | 0.5 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.0 | 0.8 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.0 | 0.6 | PID ENDOTHELIN PATHWAY | Endothelins |
| 0.0 | 1.2 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 0.5 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.0 | 0.4 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.0 | 0.3 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.0 | 0.1 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 5.6 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.3 | 9.1 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.2 | 3.3 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.2 | 12.0 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.2 | 4.1 | REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
| 0.2 | 2.2 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.2 | 5.1 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.2 | 3.6 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.1 | 6.1 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.1 | 1.3 | REACTOME FATTY ACYL COA BIOSYNTHESIS | Genes involved in Fatty Acyl-CoA Biosynthesis |
| 0.1 | 2.3 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.1 | 2.2 | REACTOME POL SWITCHING | Genes involved in Polymerase switching |
| 0.1 | 3.4 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.1 | 2.4 | REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR | Genes involved in Signaling by constitutively active EGFR |
| 0.1 | 4.2 | REACTOME CD28 DEPENDENT PI3K AKT SIGNALING | Genes involved in CD28 dependent PI3K/Akt signaling |
| 0.1 | 2.4 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
| 0.1 | 1.5 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.1 | 3.0 | REACTOME SPRY REGULATION OF FGF SIGNALING | Genes involved in Spry regulation of FGF signaling |
| 0.1 | 1.9 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 0.1 | 2.3 | REACTOME VIRAL MESSENGER RNA SYNTHESIS | Genes involved in Viral Messenger RNA Synthesis |
| 0.1 | 2.9 | REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 0.1 | 1.0 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.1 | 2.5 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 0.1 | 3.0 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.1 | 1.5 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.1 | 1.5 | REACTOME INTEGRATION OF PROVIRUS | Genes involved in Integration of provirus |
| 0.1 | 3.4 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
| 0.1 | 1.1 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.1 | 4.6 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.1 | 0.6 | REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX | Genes involved in TRAF6 mediated induction of TAK1 complex |
| 0.1 | 1.5 | REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
| 0.1 | 3.2 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.1 | 4.3 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.1 | 2.0 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.1 | 2.4 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.1 | 1.2 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.1 | 0.6 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.1 | 0.8 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.1 | 0.9 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.0 | 0.6 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.0 | 0.9 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.0 | 1.2 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.0 | 0.5 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.0 | 0.9 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.0 | 1.6 | REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
| 0.0 | 0.5 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.0 | 0.8 | REACTOME GPVI MEDIATED ACTIVATION CASCADE | Genes involved in GPVI-mediated activation cascade |
| 0.0 | 0.9 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.0 | 0.6 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.0 | 0.2 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.0 | 0.5 | REACTOME ACTIVATION OF NF KAPPAB IN B CELLS | Genes involved in Activation of NF-kappaB in B Cells |
| 0.0 | 6.2 | REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
| 0.0 | 1.0 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 0.2 | REACTOME DESTABILIZATION OF MRNA BY BRF1 | Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1) |
| 0.0 | 3.7 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
| 0.0 | 0.9 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.0 | 0.6 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.0 | 1.3 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.0 | 0.5 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 0.0 | 4.4 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.0 | 1.2 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.0 | 2.4 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 0.9 | REACTOME INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.0 | 1.2 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 0.2 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 0.0 | 0.9 | REACTOME PYRUVATE METABOLISM | Genes involved in Pyruvate metabolism |
| 0.0 | 0.6 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.0 | 1.9 | REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 0.0 | 2.5 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.0 | 0.7 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.0 | 0.6 | REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
| 0.0 | 1.0 | REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | Genes involved in Downstream signal transduction |
| 0.0 | 2.0 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 0.3 | REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX | Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex |
| 0.0 | 0.2 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.0 | 2.0 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.0 | 0.7 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 1.2 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 1.1 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 0.4 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.0 | 3.7 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 0.0 | 1.5 | REACTOME PHASE II CONJUGATION | Genes involved in Phase II conjugation |
| 0.0 | 0.3 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.0 | 0.4 | REACTOME IL 2 SIGNALING | Genes involved in Interleukin-2 signaling |
| 0.0 | 1.8 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.0 | 0.2 | REACTOME GLUCAGON TYPE LIGAND RECEPTORS | Genes involved in Glucagon-type ligand receptors |
| 0.0 | 1.2 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 0.1 | REACTOME SIGNALING BY SCF KIT | Genes involved in Signaling by SCF-KIT |
| 0.0 | 0.3 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.0 | 0.1 | REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |