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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for SREBF2

Z-value: 0.82

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Transcription factors associated with SREBF2

Gene Symbol Gene ID Gene Info
SREBF2
ENSG00000198911.12 SREBF2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SREBF2hg38_v1_chr22_+_41833079_418331420.675.5e-05Click!

Activity profile of SREBF2 motif

Sorted Z-values of SREBF2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SREBF2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_+_151239951 4.50 ENST00000402676.7
AKAP12
A-kinase anchoring protein 12
chr4_+_74365136 3.47 ENST00000244869.3
EREG
epiregulin
chr1_+_55039511 3.34 ENST00000302118.5
PCSK9
proprotein convertase subtilisin/kexin type 9
chr8_+_26577843 3.01 ENST00000311151.9
DPYSL2
dihydropyrimidinase like 2
chr19_+_11089446 2.47 ENST00000557933.5
ENST00000455727.6
ENST00000535915.5
ENST00000545707.5
ENST00000558518.6
ENST00000558013.5
LDLR
low density lipoprotein receptor
chr20_+_34876603 1.99 ENST00000360596.7
ENST00000253382.5
ACSS2
acyl-CoA synthetase short chain family member 2
chr2_-_25982471 1.88 ENST00000264712.8
KIF3C
kinesin family member 3C
chr6_-_53348902 1.85 ENST00000370913.5
ENST00000304434.11
ELOVL5
ELOVL fatty acid elongase 5
chr18_-_23586422 1.82 ENST00000269228.10
NPC1
NPC intracellular cholesterol transporter 1
chr17_-_82098187 1.79 ENST00000634990.1
FASN
fatty acid synthase
chr5_-_43313473 1.49 ENST00000433297.2
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1
chr10_-_3785225 1.46 ENST00000542957.1
KLF6
Kruppel like factor 6
chr10_-_73096850 1.45 ENST00000307116.6
ENST00000373008.6
ENST00000394890.7
P4HA1
prolyl 4-hydroxylase subunit alpha 1
chr5_-_43313403 1.45 ENST00000325110.11
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1
chr19_-_14112641 1.41 ENST00000536649.5
PRKACA
protein kinase cAMP-activated catalytic subunit alpha
chr10_-_3785197 1.40 ENST00000497571.6
KLF6
Kruppel like factor 6
chr10_-_73096974 1.38 ENST00000440381.5
ENST00000263556.3
P4HA1
prolyl 4-hydroxylase subunit alpha 1
chr3_+_50269140 1.37 ENST00000616701.5
ENST00000433753.4
ENST00000611067.4
SEMA3B
semaphorin 3B
chr17_-_41918944 1.35 ENST00000352035.7
ENST00000590770.5
ENST00000590151.5
ACLY
ATP citrate lyase
chr17_-_41918966 1.34 ENST00000537919.5
ENST00000353196.5
ENST00000393896.6
ACLY
ATP citrate lyase
chr8_+_11802667 1.27 ENST00000443614.6
ENST00000220584.9
ENST00000525900.5
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr16_+_30183595 1.17 ENST00000219150.10
ENST00000570045.5
ENST00000565497.5
ENST00000570244.5
CORO1A
coronin 1A
chr1_-_41918666 1.16 ENST00000372584.5
HIVEP3
HIVEP zinc finger 3
chr3_+_183253795 1.14 ENST00000460419.1
B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr6_-_32184227 1.12 ENST00000450110.5
ENST00000375067.7
ENST00000375056.6
AGER
advanced glycosylation end-product specific receptor
chr8_+_11802611 1.09 ENST00000623368.3
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr3_+_160399630 0.99 ENST00000465903.5
ENST00000485645.5
ENST00000472991.5
ENST00000467468.5
ENST00000469762.5
ENST00000357388.8
ENST00000489573.5
ENST00000462787.5
ENST00000490207.5
ENST00000485867.5
SMC4
structural maintenance of chromosomes 4
chr8_-_123416327 0.99 ENST00000521903.5
ATAD2
ATPase family AAA domain containing 2
chr11_+_2902258 0.97 ENST00000649076.2
ENST00000449793.6
SLC22A18
solute carrier family 22 member 18
chr19_-_11197516 0.97 ENST00000592903.5
ENST00000586659.6
ENST00000589359.5
ENST00000588724.5
KANK2
KN motif and ankyrin repeat domains 2
chr5_-_150290093 0.90 ENST00000672479.1
CAMK2A
calcium/calmodulin dependent protein kinase II alpha
chr15_+_67067780 0.89 ENST00000679624.1
SMAD3
SMAD family member 3
chr11_+_2902388 0.88 ENST00000380574.5
SLC22A18
solute carrier family 22 member 18
chr19_+_55080363 0.78 ENST00000588359.5
ENST00000245618.5
EPS8L1
EPS8 like 1
chr3_+_183253230 0.78 ENST00000326505.4
B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr3_+_189171948 0.74 ENST00000345063.8
TPRG1
tumor protein p63 regulated 1
chr22_+_41833079 0.72 ENST00000612482.4
ENST00000361204.9
SREBF2
sterol regulatory element binding transcription factor 2
chr17_-_41118369 0.69 ENST00000391413.4
KRTAP4-11
keratin associated protein 4-11
chr12_-_52949818 0.67 ENST00000546897.5
ENST00000552551.5
KRT8
keratin 8
chr10_-_3785179 0.67 ENST00000469435.1
KLF6
Kruppel like factor 6
chr6_+_41637005 0.63 ENST00000419164.6
ENST00000373051.6
MDFI
MyoD family inhibitor
chr3_-_171810432 0.58 ENST00000356327.9
ENST00000351298.9
PLD1
phospholipase D1
chr7_-_44541318 0.51 ENST00000381160.8
NPC1L1
NPC1 like intracellular cholesterol transporter 1
chr19_-_13938371 0.50 ENST00000588872.3
ENST00000339560.10
PODNL1
podocan like 1
chr6_-_32184287 0.49 ENST00000375069.7
ENST00000375070.7
ENST00000438221.6
ENST00000620802.4
ENST00000538695.2
AGER
advanced glycosylation end-product specific receptor
chr5_+_138439020 0.48 ENST00000378339.7
ENST00000254901.9
ENST00000506158.5
REEP2
receptor accessory protein 2
chr17_+_81103998 0.47 ENST00000572498.1
BAIAP2
BAR/IMD domain containing adaptor protein 2
chr3_+_46701385 0.42 ENST00000643606.3
TMIE
transmembrane inner ear
chr7_-_44541262 0.42 ENST00000289547.8
ENST00000546276.5
ENST00000423141.1
NPC1L1
NPC1 like intracellular cholesterol transporter 1
chr8_+_123416718 0.41 ENST00000523984.5
NTAQ1
N-terminal glutamine amidase 1
chr6_+_117265550 0.40 ENST00000352536.7
ENST00000326274.6
VGLL2
vestigial like family member 2
chr8_+_123416766 0.40 ENST00000287387.7
ENST00000650311.1
ENST00000523356.1
NTAQ1
N-terminal glutamine amidase 1
chr19_-_13937991 0.39 ENST00000254320.7
ENST00000586075.1
PODNL1
podocan like 1
chr5_-_108367860 0.37 ENST00000496714.2
FBXL17
F-box and leucine rich repeat protein 17
chr14_+_32939243 0.36 ENST00000346562.6
ENST00000548645.5
ENST00000356141.8
ENST00000357798.9
NPAS3
neuronal PAS domain protein 3
chr6_-_32184243 0.34 ENST00000375055.6
ENST00000375076.9
AGER
advanced glycosylation end-product specific receptor
chr6_+_69232406 0.34 ENST00000238918.12
ADGRB3
adhesion G protein-coupled receptor B3
chr5_-_39424966 0.32 ENST00000515700.5
ENST00000320816.11
ENST00000339788.10
DAB2
DAB adaptor protein 2
chrX_+_47370578 0.29 ENST00000377073.4
ZNF157
zinc finger protein 157
chr6_-_31958431 0.28 ENST00000625905.1
ENST00000454913.5
ENST00000436289.6
NELFE
negative elongation factor complex member E
chr12_+_49950733 0.28 ENST00000199280.4
ENST00000550862.1
AQP2
aquaporin 2
chr3_-_160399512 0.28 ENST00000498409.5
ENST00000475677.5
ENST00000478536.1
IFT80
intraflagellar transport 80
chr8_+_103500696 0.27 ENST00000666250.1
ENST00000668113.1
ENST00000504942.6
ENST00000632716.1
RIMS2
regulating synaptic membrane exocytosis 2
chr19_-_45782479 0.25 ENST00000447742.6
ENST00000354227.9
ENST00000291270.9
ENST00000683086.1
ENST00000343373.10
DMPK
DM1 protein kinase
chr1_+_197268222 0.23 ENST00000367400.8
ENST00000638467.1
ENST00000367399.6
CRB1
crumbs cell polarity complex component 1
chr22_-_31140494 0.22 ENST00000215885.4
PLA2G3
phospholipase A2 group III
chr15_-_82952683 0.22 ENST00000450735.7
ENST00000304231.12
HOMER2
homer scaffold protein 2
chr8_+_123416735 0.21 ENST00000524254.5
NTAQ1
N-terminal glutamine amidase 1
chr19_-_18281612 0.19 ENST00000252818.5
JUND
JunD proto-oncogene, AP-1 transcription factor subunit
chr14_-_74493322 0.18 ENST00000553490.5
ENST00000557510.5
NPC2
NPC intracellular cholesterol transporter 2
chr14_-_74493275 0.16 ENST00000541064.5
NPC2
NPC intracellular cholesterol transporter 2
chr3_-_56683218 0.16 ENST00000355628.9
ENST00000683822.1
TASOR
transcription activation suppressor
chr15_+_32717994 0.15 ENST00000560677.5
ENST00000560830.1
ENST00000651154.1
GREM1
gremlin 1, DAN family BMP antagonist
chr14_-_74493291 0.15 ENST00000238633.6
ENST00000555619.6
ENST00000434013.6
NPC2
NPC intracellular cholesterol transporter 2
chr1_+_112619824 0.14 ENST00000263168.4
CAPZA1
capping actin protein of muscle Z-line subunit alpha 1
chr1_+_197268204 0.13 ENST00000535699.5
ENST00000538660.5
CRB1
crumbs cell polarity complex component 1
chr17_+_67044530 0.11 ENST00000226021.5
CACNG1
calcium voltage-gated channel auxiliary subunit gamma 1
chr1_+_32013848 0.11 ENST00000327300.12
ENST00000492989.1
KHDRBS1
KH RNA binding domain containing, signal transduction associated 1
chr11_+_75240761 0.10 ENST00000562197.3
TPBGL
trophoblast glycoprotein like
chr6_+_12012304 0.10 ENST00000379388.7
ENST00000627968.2
ENST00000541134.5
HIVEP1
HIVEP zinc finger 1
chr17_+_75261864 0.07 ENST00000245539.11
ENST00000579002.5
MRPS7
mitochondrial ribosomal protein S7
chr22_+_23772839 0.07 ENST00000215743.8
MMP11
matrix metallopeptidase 11
chr11_-_6655788 0.06 ENST00000299441.5
DCHS1
dachsous cadherin-related 1
chr8_+_22024731 0.05 ENST00000289820.10
ENST00000381530.9
NPM2
nucleophosmin/nucleoplasmin 2
chr17_+_75261661 0.05 ENST00000579761.5
MRPS7
mitochondrial ribosomal protein S7
chr9_+_128689948 0.02 ENST00000372688.8
ENST00000372686.5
SET
SET nuclear proto-oncogene
chrX_-_153971810 0.01 ENST00000310441.12
HCFC1
host cell factor C1
chr11_+_64291992 0.01 ENST00000394525.6
KCNK4
potassium two pore domain channel subfamily K member 4
chr2_+_27212866 0.01 ENST00000419744.1
ATRAID
all-trans retinoic acid induced differentiation factor
chr1_+_32753991 0.00 ENST00000373481.7
KIAA1522
KIAA1522

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.7 2.0 GO:0019413 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate biosynthetic process(GO:0019542)
0.6 1.9 GO:1904597 regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204)
0.6 2.5 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.5 3.5 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.4 2.4 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.4 4.5 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.3 1.0 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.2 2.8 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.2 1.9 GO:0046618 drug export(GO:0046618)
0.2 1.2 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.2 2.9 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.2 1.8 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.2 1.9 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 1.0 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.9 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.7 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 1.8 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 2.7 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.1 0.3 GO:0035026 leading edge cell differentiation(GO:0035026)
0.1 0.3 GO:0071288 cellular response to mercury ion(GO:0071288)
0.1 0.3 GO:0099558 maintenance of synapse structure(GO:0099558)
0.1 1.0 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.5 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.1 0.5 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.1 1.4 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 0.5 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.1 0.6 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.0 0.8 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.7 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.9 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.9 GO:0098856 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 2.2 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.6 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 1.4 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.3 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0003192 mitral valve formation(GO:0003192)
0.0 0.1 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.0 1.9 GO:0016266 O-glycan processing(GO:0016266)
0.0 3.0 GO:0030516 regulation of axon extension(GO:0030516)
0.0 3.5 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.2 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.0 0.3 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.9 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 1.2 GO:0035914 skeletal muscle cell differentiation(GO:0035914)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.9 2.8 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.2 0.7 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 1.8 GO:0042587 glycogen granule(GO:0042587)
0.1 1.0 GO:0000796 condensin complex(GO:0000796)
0.1 0.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 1.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.3 GO:0032021 NELF complex(GO:0032021)
0.0 2.2 GO:0097542 ciliary tip(GO:0097542)
0.0 1.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 5.5 GO:0001650 fibrillar center(GO:0001650)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.0 3.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.0 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.0 2.4 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.9 GO:0031526 brush border membrane(GO:0031526)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0004157 dihydropyrimidinase activity(GO:0004157)
1.0 2.9 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.8 3.3 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.6 1.9 GO:1904599 advanced glycation end-product binding(GO:1904599)
0.6 1.9 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.6 1.8 GO:0016419 [acyl-carrier-protein] S-malonyltransferase activity(GO:0004314) 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420)
0.5 2.7 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.5 2.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.5 2.5 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.5 2.8 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.4 2.4 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.3 1.9 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.2 0.7 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.2 4.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 1.9 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.9 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 1.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.6 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.8 GO:0042608 T cell receptor binding(GO:0042608)
0.1 1.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 1.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.9 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 1.8 GO:0015248 sterol transporter activity(GO:0015248)
0.0 2.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.9 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 1.9 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.5 GO:0098641 cytoskeletal adaptor activity(GO:0008093) cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.3 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0016015 morphogen activity(GO:0016015)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 1.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 2.0 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 2.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.9 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.6 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 2.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.0 PID AURORA B PATHWAY Aurora B signaling
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 6.3 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.1 5.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 3.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.9 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 2.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 2.7 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 1.9 REACTOME KINESINS Genes involved in Kinesins
0.0 1.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 1.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.9 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation