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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for SRY

Z-value: 0.76

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Transcription factors associated with SRY

Gene Symbol Gene ID Gene Info
SRY
ENSG00000184895.8 SRY

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SRYhg38_v1_chrY_-_2787676_2787687-0.328.6e-02Click!

Activity profile of SRY motif

Sorted Z-values of SRY motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SRY

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr13_-_38990824 4.00 ENST00000379631.9
STOML3
stomatin like 3
chr13_-_38990856 3.93 ENST00000423210.1
STOML3
stomatin like 3
chr20_-_3781440 2.85 ENST00000379756.3
SPEF1
sperm flagellar 1
chr6_-_32589833 2.83 ENST00000360004.5
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
chr4_+_164754045 2.63 ENST00000515485.5
SMIM31
small integral membrane protein 31
chr6_+_162727941 2.33 ENST00000366888.6
PACRG
parkin coregulated
chr17_+_38705482 2.20 ENST00000620609.4
MLLT6
MLLT6, PHD finger containing
chr17_+_17972813 1.95 ENST00000582416.5
ENST00000313838.12
ENST00000399187.6
ENST00000581264.5
ENST00000479684.2
ENST00000584166.5
ENST00000585108.5
ENST00000399182.5
ENST00000579977.1
DRC3
dynein regulatory complex subunit 3
chr7_+_114414809 1.91 ENST00000350908.9
FOXP2
forkhead box P2
chr4_+_164754116 1.88 ENST00000507311.1
SMIM31
small integral membrane protein 31
chr1_-_217137748 1.54 ENST00000493603.5
ENST00000366940.6
ESRRG
estrogen related receptor gamma
chr8_-_71361860 1.44 ENST00000303824.11
ENST00000645451.1
EYA1
EYA transcriptional coactivator and phosphatase 1
chr2_-_86337654 1.43 ENST00000165698.9
REEP1
receptor accessory protein 1
chr2_-_86337617 1.43 ENST00000538924.7
ENST00000535845.6
REEP1
receptor accessory protein 1
chr14_-_91947654 1.37 ENST00000342058.9
FBLN5
fibulin 5
chr14_-_91947383 1.31 ENST00000267620.14
FBLN5
fibulin 5
chr1_-_39901996 1.30 ENST00000397332.2
MYCL
MYCL proto-oncogene, bHLH transcription factor
chr1_-_217076889 1.22 ENST00000493748.5
ENST00000463665.5
ESRRG
estrogen related receptor gamma
chr7_-_117873420 1.19 ENST00000160373.8
CTTNBP2
cortactin binding protein 2
chr1_+_61081728 1.17 ENST00000371189.8
NFIA
nuclear factor I A
chr17_-_58328756 1.15 ENST00000268893.10
ENST00000343736.9
TSPOAP1
TSPO associated protein 1
chr10_-_60572599 1.12 ENST00000503366.5
ANK3
ankyrin 3
chr6_-_152168349 1.10 ENST00000539504.5
SYNE1
spectrin repeat containing nuclear envelope protein 1
chr6_-_152168291 1.07 ENST00000354674.5
SYNE1
spectrin repeat containing nuclear envelope protein 1
chr20_-_21514046 1.03 ENST00000377142.5
NKX2-2
NK2 homeobox 2
chr8_-_71547626 1.00 ENST00000647540.1
ENST00000644229.1
EYA1
EYA transcriptional coactivator and phosphatase 1
chr14_-_91946989 0.95 ENST00000556154.5
FBLN5
fibulin 5
chr14_-_22819721 0.94 ENST00000554517.5
ENST00000285850.11
ENST00000397529.6
ENST00000555702.5
SLC7A7
solute carrier family 7 member 7
chr2_-_74421560 0.90 ENST00000612891.4
ENST00000640331.1
ENST00000684111.1
C2orf81
chromosome 2 open reading frame 81
chr9_+_2110354 0.88 ENST00000634772.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr19_+_13023958 0.88 ENST00000587760.5
ENST00000585575.5
NFIX
nuclear factor I X
chr2_-_156342348 0.85 ENST00000409572.5
NR4A2
nuclear receptor subfamily 4 group A member 2
chr10_+_113125536 0.84 ENST00000349937.7
TCF7L2
transcription factor 7 like 2
chr10_-_60141004 0.83 ENST00000355288.6
ANK3
ankyrin 3
chr1_-_39901861 0.83 ENST00000372816.3
ENST00000372815.1
MYCL
MYCL proto-oncogene, bHLH transcription factor
chr11_+_36296281 0.82 ENST00000530639.6
PRR5L
proline rich 5 like
chr6_-_31684040 0.82 ENST00000375863.7
LY6G5C
lymphocyte antigen 6 family member G5C
chr3_-_11568764 0.81 ENST00000424529.6
VGLL4
vestigial like family member 4
chr14_+_91114667 0.81 ENST00000523894.5
ENST00000522322.5
ENST00000523771.5
DGLUCY
D-glutamate cyclase
chr7_-_78771265 0.80 ENST00000630991.2
ENST00000629359.2
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr5_+_140868945 0.79 ENST00000398640.7
PCDHA11
protocadherin alpha 11
chr22_-_31345770 0.77 ENST00000215919.3
PATZ1
POZ/BTB and AT hook containing zinc finger 1
chr18_-_55321986 0.77 ENST00000570287.6
TCF4
transcription factor 4
chr14_-_89417148 0.76 ENST00000557258.6
FOXN3
forkhead box N3
chr1_+_33256479 0.75 ENST00000539719.6
ENST00000483388.5
ZNF362
zinc finger protein 362
chr2_+_190408324 0.75 ENST00000417958.5
ENST00000432036.5
ENST00000392328.6
MFSD6
major facilitator superfamily domain containing 6
chr9_-_122227525 0.74 ENST00000373755.6
ENST00000373754.6
LHX6
LIM homeobox 6
chr14_+_91114431 0.74 ENST00000428926.6
ENST00000517362.5
DGLUCY
D-glutamate cyclase
chr11_-_85686123 0.73 ENST00000316398.5
CCDC89
coiled-coil domain containing 89
chr14_+_91114364 0.72 ENST00000518868.5
DGLUCY
D-glutamate cyclase
chr10_-_60389833 0.72 ENST00000280772.7
ANK3
ankyrin 3
chr17_+_9021501 0.72 ENST00000173229.7
NTN1
netrin 1
chr5_-_111756245 0.72 ENST00000447165.6
NREP
neuronal regeneration related protein
chr1_+_61082553 0.70 ENST00000403491.8
ENST00000371187.7
NFIA
nuclear factor I A
chr10_+_97319250 0.70 ENST00000371021.5
FRAT1
FRAT regulator of WNT signaling pathway 1
chr4_+_94974984 0.69 ENST00000672698.1
BMPR1B
bone morphogenetic protein receptor type 1B
chr14_-_52552493 0.68 ENST00000281741.9
ENST00000557374.1
TXNDC16
thioredoxin domain containing 16
chr9_-_14314132 0.68 ENST00000380953.6
NFIB
nuclear factor I B
chr9_-_134068518 0.67 ENST00000371834.6
BRD3
bromodomain containing 3
chr6_+_122399536 0.67 ENST00000452194.5
HSF2
heat shock transcription factor 2
chr12_-_85836372 0.67 ENST00000361228.5
RASSF9
Ras association domain family member 9
chr18_-_55589770 0.65 ENST00000565018.6
ENST00000636400.2
TCF4
transcription factor 4
chr6_+_122399621 0.65 ENST00000368455.9
HSF2
heat shock transcription factor 2
chr16_-_68448491 0.65 ENST00000561749.1
ENST00000219334.10
SMPD3
sphingomyelin phosphodiesterase 3
chr6_-_87095059 0.65 ENST00000369582.6
ENST00000610310.3
ENST00000630630.2
ENST00000627148.3
ENST00000625577.1
CGA
glycoprotein hormones, alpha polypeptide
chr9_-_71768386 0.63 ENST00000377066.9
ENST00000377044.9
CEMIP2
cell migration inducing hyaluronidase 2
chr10_-_97334698 0.60 ENST00000371019.4
FRAT2
FRAT regulator of WNT signaling pathway 2
chr18_+_75210789 0.60 ENST00000580243.3
TSHZ1
teashirt zinc finger homeobox 1
chr11_-_16356538 0.58 ENST00000683767.1
SOX6
SRY-box transcription factor 6
chr18_-_55351977 0.58 ENST00000643689.1
TCF4
transcription factor 4
chr1_+_87328860 0.58 ENST00000370544.10
LMO4
LIM domain only 4
chr1_-_56579555 0.57 ENST00000371250.4
PLPP3
phospholipid phosphatase 3
chr2_+_86441341 0.57 ENST00000312912.10
ENST00000409064.5
KDM3A
lysine demethylase 3A
chr18_-_55321640 0.57 ENST00000637169.2
TCF4
transcription factor 4
chr18_+_75210755 0.56 ENST00000322038.5
TSHZ1
teashirt zinc finger homeobox 1
chr2_-_71227055 0.56 ENST00000244221.9
PAIP2B
poly(A) binding protein interacting protein 2B
chr7_+_114414997 0.56 ENST00000462331.5
ENST00000393491.7
ENST00000403559.8
ENST00000408937.7
ENST00000393498.6
ENST00000393495.7
ENST00000378237.7
FOXP2
forkhead box P2
chr4_-_104494882 0.55 ENST00000394767.3
CXXC4
CXXC finger protein 4
chr18_-_55322215 0.53 ENST00000457482.7
TCF4
transcription factor 4
chr9_+_27109393 0.53 ENST00000406359.8
TEK
TEK receptor tyrosine kinase
chr5_-_147081428 0.52 ENST00000394413.7
PPP2R2B
protein phosphatase 2 regulatory subunit Bbeta
chr4_+_41612892 0.52 ENST00000509454.5
ENST00000396595.7
ENST00000381753.8
LIMCH1
LIM and calponin homology domains 1
chr19_+_13795434 0.52 ENST00000254323.6
ZSWIM4
zinc finger SWIM-type containing 4
chr17_+_59331633 0.50 ENST00000312655.9
YPEL2
yippee like 2
chr18_-_55589795 0.50 ENST00000568740.5
ENST00000629387.2
TCF4
transcription factor 4
chr6_+_156777366 0.50 ENST00000636930.2
ARID1B
AT-rich interaction domain 1B
chr1_+_40374648 0.50 ENST00000372708.5
SMAP2
small ArfGAP2
chr9_-_127980976 0.50 ENST00000373095.6
FAM102A
family with sequence similarity 102 member A
chr12_-_122500924 0.48 ENST00000633063.3
ZCCHC8
zinc finger CCHC-type containing 8
chr21_-_17819343 0.48 ENST00000284881.9
C21orf91
chromosome 21 open reading frame 91
chr18_-_55589836 0.48 ENST00000537578.5
ENST00000564403.6
TCF4
transcription factor 4
chr18_-_55635948 0.47 ENST00000565124.4
ENST00000398339.5
TCF4
transcription factor 4
chr4_-_173530219 0.47 ENST00000359562.4
HAND2
heart and neural crest derivatives expressed 2
chr10_-_50279715 0.47 ENST00000395526.9
ASAH2
N-acylsphingosine amidohydrolase 2
chr12_-_122500947 0.46 ENST00000672018.1
ZCCHC8
zinc finger CCHC-type containing 8
chr5_-_147056010 0.46 ENST00000394414.5
PPP2R2B
protein phosphatase 2 regulatory subunit Bbeta
chr3_-_112641292 0.45 ENST00000439685.6
CCDC80
coiled-coil domain containing 80
chr6_+_156777882 0.44 ENST00000350026.10
ENST00000647938.1
ENST00000674298.1
ARID1B
AT-rich interaction domain 1B
chr5_-_147055968 0.44 ENST00000336640.10
PPP2R2B
protein phosphatase 2 regulatory subunit Bbeta
chr14_+_91114388 0.43 ENST00000519019.5
ENST00000523816.5
ENST00000517518.5
DGLUCY
D-glutamate cyclase
chr12_-_122500520 0.41 ENST00000540586.1
ENST00000543897.5
ZCCHC8
zinc finger CCHC-type containing 8
chr7_+_30145789 0.41 ENST00000324489.5
MTURN
maturin, neural progenitor differentiation regulator homolog
chr11_-_95910824 0.41 ENST00000674528.1
ENST00000675477.1
ENST00000675636.1
MTMR2
myotubularin related protein 2
chr6_+_138773747 0.40 ENST00000617445.5
CCDC28A
coiled-coil domain containing 28A
chr3_-_142149515 0.40 ENST00000475734.5
ENST00000467072.5
ENST00000489671.6
TFDP2
transcription factor Dp-2
chr19_+_13024917 0.39 ENST00000587260.1
NFIX
nuclear factor I X
chr12_-_24562438 0.39 ENST00000646273.1
ENST00000659413.1
ENST00000446891.7
SOX5
SRY-box transcription factor 5
chr7_-_78771108 0.39 ENST00000626691.2
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chrX_-_24672654 0.39 ENST00000379145.5
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr18_-_55302613 0.38 ENST00000561831.7
TCF4
transcription factor 4
chr14_+_91114026 0.38 ENST00000521081.5
ENST00000520328.5
ENST00000524232.5
ENST00000522170.5
ENST00000256324.15
ENST00000519950.5
ENST00000523879.5
ENST00000521077.6
ENST00000518665.6
DGLUCY
D-glutamate cyclase
chr10_+_91162958 0.38 ENST00000614189.4
PCGF5
polycomb group ring finger 5
chr11_-_95910748 0.38 ENST00000675933.1
MTMR2
myotubularin related protein 2
chr11_-_95910665 0.38 ENST00000674610.1
ENST00000675660.1
MTMR2
myotubularin related protein 2
chr20_+_10435283 0.37 ENST00000334534.10
SLX4IP
SLX4 interacting protein
chr1_+_40709475 0.37 ENST00000372651.5
NFYC
nuclear transcription factor Y subunit gamma
chr11_-_44950151 0.37 ENST00000533940.5
ENST00000533937.1
TP53I11
tumor protein p53 inducible protein 11
chr8_+_109334317 0.36 ENST00000521662.5
ENST00000520147.5
ENST00000521688.6
ENY2
ENY2 transcription and export complex 2 subunit
chr2_-_159616442 0.36 ENST00000541068.6
ENST00000392783.7
ENST00000392782.5
BAZ2B
bromodomain adjacent to zinc finger domain 2B
chr21_-_17819386 0.35 ENST00000400559.7
ENST00000400558.7
C21orf91
chromosome 21 open reading frame 91
chr11_-_115504389 0.35 ENST00000545380.5
ENST00000452722.7
ENST00000331581.11
ENST00000537058.5
ENST00000536727.5
ENST00000542447.6
CADM1
cell adhesion molecule 1
chr1_-_52552994 0.34 ENST00000355809.4
ENST00000528642.5
ENST00000470626.1
ENST00000257177.9
ENST00000371544.7
TUT4
terminal uridylyl transferase 4
chr16_+_2537997 0.34 ENST00000441549.7
ENST00000268673.11
ENST00000342085.9
ENST00000389224.7
PDPK1
3-phosphoinositide dependent protein kinase 1
chr5_-_147081462 0.34 ENST00000508267.5
ENST00000504198.5
PPP2R2B
protein phosphatase 2 regulatory subunit Bbeta
chr18_+_58341038 0.34 ENST00000679791.1
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr1_-_107688492 0.33 ENST00000415432.6
VAV3
vav guanine nucleotide exchange factor 3
chr9_-_134068012 0.32 ENST00000303407.12
BRD3
bromodomain containing 3
chr9_-_14314567 0.32 ENST00000397579.6
NFIB
nuclear factor I B
chr10_+_110207587 0.32 ENST00000332674.9
ENST00000453116.5
MXI1
MAX interactor 1, dimerization protein
chr7_-_93226449 0.31 ENST00000394468.7
ENST00000453812.2
HEPACAM2
HEPACAM family member 2
chr2_+_27442365 0.31 ENST00000543753.5
ENST00000288873.7
KRTCAP3
keratinocyte associated protein 3
chr4_+_169660062 0.30 ENST00000507875.5
ENST00000613795.4
CLCN3
chloride voltage-gated channel 3
chr10_-_48274567 0.30 ENST00000636244.1
ENST00000374201.8
FRMPD2
FERM and PDZ domain containing 2
chr9_+_2159672 0.30 ENST00000634343.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_-_177164673 0.30 ENST00000424564.2
ENST00000361833.7
ASTN1
astrotactin 1
chr15_-_53733103 0.29 ENST00000559418.5
WDR72
WD repeat domain 72
chr2_-_231125032 0.28 ENST00000258400.4
HTR2B
5-hydroxytryptamine receptor 2B
chr8_-_56211257 0.28 ENST00000316981.8
ENST00000423799.6
ENST00000429357.2
PLAG1
PLAG1 zinc finger
chrX_+_15507302 0.28 ENST00000342014.6
BMX
BMX non-receptor tyrosine kinase
chr2_+_27442421 0.28 ENST00000407293.5
KRTCAP3
keratinocyte associated protein 3
chr11_+_31816266 0.27 ENST00000644607.1
ENST00000646221.1
ENST00000643671.1
ENST00000643931.1
ENST00000642614.1
ENST00000642818.1
ENST00000645848.1
ENST00000506388.2
ENST00000645824.1
ENST00000532942.5
PAUPAR
ENSG00000285283.1
PAX6 upstream antisense RNA
novel protein
chr8_-_143986425 0.27 ENST00000313059.9
ENST00000524918.5
ENST00000313028.12
ENST00000525773.5
PARP10
poly(ADP-ribose) polymerase family member 10
chr6_-_116060859 0.26 ENST00000606080.2
FRK
fyn related Src family tyrosine kinase
chr1_+_164559739 0.25 ENST00000627490.2
PBX1
PBX homeobox 1
chr5_+_141177790 0.25 ENST00000239444.4
ENST00000623995.1
PCDHB8
ENSG00000279472.1
protocadherin beta 8
novel transcript
chr16_-_3880678 0.25 ENST00000262367.10
CREBBP
CREB binding protein
chr9_-_14313843 0.24 ENST00000636063.1
ENST00000380921.3
ENST00000622520.1
ENST00000380959.7
NFIB
nuclear factor I B
chr10_-_32378720 0.24 ENST00000375110.6
EPC1
enhancer of polycomb homolog 1
chr9_-_14314519 0.24 ENST00000397581.6
NFIB
nuclear factor I B
chr13_-_40771105 0.23 ENST00000323563.8
MRPS31
mitochondrial ribosomal protein S31
chr3_+_142623386 0.23 ENST00000337777.7
ENST00000497199.5
PLS1
plastin 1
chr2_+_108588286 0.23 ENST00000332345.10
LIMS1
LIM zinc finger domain containing 1
chr1_+_43389889 0.23 ENST00000562955.2
ENST00000634258.3
SZT2
SZT2 subunit of KICSTOR complex
chr12_-_10098977 0.23 ENST00000315330.8
ENST00000457018.6
CLEC1A
C-type lectin domain family 1 member A
chr9_-_37465402 0.23 ENST00000307750.5
ZBTB5
zinc finger and BTB domain containing 5
chr19_-_47231191 0.22 ENST00000439096.3
BBC3
BCL2 binding component 3
chr1_+_40709316 0.22 ENST00000372652.5
NFYC
nuclear transcription factor Y subunit gamma
chr12_+_389334 0.22 ENST00000540180.5
ENST00000422000.5
ENST00000535052.5
CCDC77
coiled-coil domain containing 77
chr3_-_58666765 0.21 ENST00000358781.7
FAM3D
FAM3 metabolism regulating signaling molecule D
chr1_+_147902789 0.21 ENST00000369235.2
GJA8
gap junction protein alpha 8
chr3_+_41194741 0.21 ENST00000643541.1
ENST00000426215.5
ENST00000645210.1
ENST00000646381.1
ENST00000405570.6
ENST00000642248.1
ENST00000433400.6
CTNNB1
catenin beta 1
chr12_-_389249 0.21 ENST00000535014.5
ENST00000543507.1
ENST00000544760.1
ENST00000399788.7
KDM5A
lysine demethylase 5A
chr16_+_28846674 0.21 ENST00000322610.12
SH2B1
SH2B adaptor protein 1
chr16_-_46763237 0.21 ENST00000536476.5
MYLK3
myosin light chain kinase 3
chr7_-_19773569 0.21 ENST00000422233.5
ENST00000433641.5
ENST00000405844.6
TMEM196
transmembrane protein 196
chr14_+_52553273 0.20 ENST00000542169.6
ENST00000555622.1
GPR137C
G protein-coupled receptor 137C
chr14_+_52552830 0.20 ENST00000321662.11
GPR137C
G protein-coupled receptor 137C
chr1_+_164559766 0.20 ENST00000367897.5
ENST00000559240.5
PBX1
PBX homeobox 1
chr20_-_56497608 0.20 ENST00000617620.1
GCNT7
glucosaminyl (N-acetyl) transferase family member 7
chr17_-_75515509 0.20 ENST00000321617.8
CASKIN2
CASK interacting protein 2
chr8_-_42501224 0.20 ENST00000520262.6
ENST00000517366.1
SLC20A2
solute carrier family 20 member 2
chr9_-_14313642 0.20 ENST00000637742.1
NFIB
nuclear factor I B
chr1_+_235327344 0.19 ENST00000488594.5
GGPS1
geranylgeranyl diphosphate synthase 1
chr1_+_84164684 0.19 ENST00000370680.5
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr13_-_40666600 0.19 ENST00000379561.6
FOXO1
forkhead box O1
chr3_-_62373015 0.19 ENST00000475839.1
FEZF2
FEZ family zinc finger 2
chr8_-_86743626 0.19 ENST00000320005.6
CNGB3
cyclic nucleotide gated channel subunit beta 3
chr15_+_76336755 0.19 ENST00000290759.9
ISL2
ISL LIM homeobox 2
chr20_+_33562365 0.19 ENST00000346541.7
ENST00000397800.5
ENST00000492345.5
CBFA2T2
CBFA2/RUNX1 partner transcriptional co-repressor 2
chr2_+_86720282 0.18 ENST00000283632.5
RMND5A
required for meiotic nuclear division 5 homolog A
chr9_-_95509241 0.18 ENST00000331920.11
PTCH1
patched 1
chr5_+_111071710 0.18 ENST00000344895.4
TSLP
thymic stromal lymphopoietin
chr11_-_30586866 0.18 ENST00000528686.2
MPPED2
metallophosphoesterase domain containing 2
chr5_+_163505564 0.18 ENST00000421814.6
ENST00000518095.5
ENST00000321757.11
MAT2B
methionine adenosyltransferase 2B
chr12_+_11649666 0.17 ENST00000396373.9
ETV6
ETS variant transcription factor 6
chr5_+_139341875 0.17 ENST00000511706.5
PAIP2
poly(A) binding protein interacting protein 2
chr22_+_19723525 0.17 ENST00000366425.4
GP1BB
glycoprotein Ib platelet subunit beta
chr2_+_134838610 0.16 ENST00000356140.10
ENST00000392928.5
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr4_+_94995919 0.16 ENST00000509540.6
BMPR1B
bone morphogenetic protein receptor type 1B
chr11_+_112961480 0.16 ENST00000621850.4
NCAM1
neural cell adhesion molecule 1
chr16_+_30395400 0.16 ENST00000320159.2
ENST00000613509.2
ZNF48
zinc finger protein 48
chr6_-_37697875 0.16 ENST00000434837.8
MDGA1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr12_-_86256267 0.15 ENST00000620241.4
MGAT4C
MGAT4 family member C
chr7_-_149028452 0.15 ENST00000413966.1
ENST00000652332.1
PDIA4
protein disulfide isomerase family A member 4
chr5_+_139342442 0.15 ENST00000394795.6
ENST00000510080.1
PAIP2
poly(A) binding protein interacting protein 2
chr14_+_58427425 0.15 ENST00000619722.5
ENST00000423743.7
KIAA0586
KIAA0586
chr7_+_29479712 0.15 ENST00000412711.6
CHN2
chimerin 2
chr2_+_108588453 0.15 ENST00000393310.5
LIMS1
LIM zinc finger domain containing 1
chr22_-_49827512 0.15 ENST00000404760.5
BRD1
bromodomain containing 1
chr13_-_99258366 0.15 ENST00000397470.5
ENST00000397473.7
GPR18
G protein-coupled receptor 18

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0021758 caudate nucleus development(GO:0021757) putamen development(GO:0021758)
0.7 2.8 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.7 2.7 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.3 1.0 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.3 3.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.3 0.6 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.3 0.8 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.3 2.4 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.3 2.1 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.2 2.2 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.2 1.2 GO:0060023 soft palate development(GO:0060023)
0.2 0.6 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.2 1.7 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.9 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 0.9 GO:1902731 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.1 0.5 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 0.9 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.1 0.6 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 2.6 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 1.2 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.1 1.0 GO:0044334 canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.1 0.7 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.1 1.2 GO:0031642 negative regulation of myelination(GO:0031642) positive regulation of early endosome to late endosome transport(GO:2000643)
0.1 0.2 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.9 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.3 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.2 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.1 1.7 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.2 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 0.3 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.3 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.4 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 0.2 GO:1902688 regulation of NAD metabolic process(GO:1902688)
0.1 0.2 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.1 0.4 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.4 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.1 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.2 GO:1902617 response to fluoride(GO:1902617)
0.0 0.7 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.7 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.2 GO:0010157 response to chlorate(GO:0010157)
0.0 1.4 GO:0072189 ureter development(GO:0072189)
0.0 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.6 GO:0008354 germ cell migration(GO:0008354) Bergmann glial cell differentiation(GO:0060020)
0.0 1.3 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 2.7 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.4 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.5 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.4 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.2 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.0 0.8 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 1.2 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.9 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.4 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.4 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.3 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.3 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.3 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 3.3 GO:0007286 spermatid development(GO:0007286)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 4.6 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 0.5 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0032599 B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0008090 retrograde axonal transport(GO:0008090)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.6 GO:0071953 elastic fiber(GO:0071953)
0.1 2.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 2.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 2.3 GO:0097225 sperm midpiece(GO:0097225)
0.1 2.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 1.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 1.0 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 2.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 0.2 GO:0034657 GID complex(GO:0034657)
0.1 0.9 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.7 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.4 GO:1990130 Iml1 complex(GO:1990130)
0.0 1.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 4.7 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 1.5 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 7.0 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.7 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.9 GO:0031849 olfactory receptor binding(GO:0031849)
0.4 1.2 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.3 2.8 GO:0050682 AF-2 domain binding(GO:0050682)
0.2 4.9 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 1.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 0.6 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 2.8 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.9 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 2.2 GO:0005521 lamin binding(GO:0005521)
0.1 0.5 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.9 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 2.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 2.7 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.2 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.2 GO:0097108 smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108)
0.0 3.1 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.5 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.5 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.3 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.9 GO:0030371 translation repressor activity(GO:0030371)
0.0 1.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 1.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.5 GO:0001968 fibronectin binding(GO:0001968)
0.0 1.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 2.1 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 3.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 5.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.9 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 0.9 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 1.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 0.3 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 4.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 2.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 0.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.7 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 1.0 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 3.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.1 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway