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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for STAT4

Z-value: 0.56

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Transcription factors associated with STAT4

Gene Symbol Gene ID Gene Info
ENSG00000138378.19 STAT4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT4hg38_v1_chr2_-_191151568_191151596,
hg38_v1_chr2_-_191150971_191151017
-0.588.7e-04Click!

Activity profile of STAT4 motif

Sorted Z-values of STAT4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_161367872 3.28 ENST00000367974.2
cilia and flagella associated protein 126
chr1_-_109112733 2.18 ENST00000369948.8
ENST00000369945.7
chromosome 1 open reading frame 194
chr6_+_32854179 1.74 ENST00000374859.3
proteasome 20S subunit beta 9
chr14_-_20802402 1.43 ENST00000412779.2
ribonuclease A family member 1, pancreatic
chr3_-_149221811 1.42 ENST00000455472.3
ENST00000264613.11
ceruloplasmin
chr20_+_9069076 1.33 ENST00000378473.9
phospholipase C beta 4
chr5_-_122078249 1.28 ENST00000231004.5
lysyl oxidase
chr8_-_109648825 1.24 ENST00000533895.5
ENST00000446070.6
ENST00000528331.5
ENST00000526302.5
ENST00000408908.6
ENST00000433638.1
ENST00000524720.5
syntabulin
chr5_+_140882116 1.23 ENST00000289272.3
ENST00000409494.5
ENST00000617769.1
protocadherin alpha 13
chr5_-_16508990 1.20 ENST00000399793.6
reticulophagy regulator 1
chr16_+_58249910 1.12 ENST00000219299.8
ENST00000443128.6
ENST00000616795.1
coiled-coil domain containing 113
chr6_-_109690515 0.95 ENST00000532976.1
adenylate kinase 9
chr22_-_37953541 0.87 ENST00000422191.1
ENST00000249079.6
ENST00000403305.6
ENST00000418863.5
ENST00000619227.4
ENST00000403026.5
chromosome 22 open reading frame 23
chr3_+_108296489 0.87 ENST00000619531.4
HERV-H LTR-associating 2
chr7_+_129502517 0.85 ENST00000462322.3
small lysine rich protein 1
chr10_-_114684612 0.84 ENST00000533213.6
ENST00000369252.8
actin binding LIM protein 1
chr6_-_109690500 0.83 ENST00000448084.6
adenylate kinase 9
chr19_+_34677723 0.79 ENST00000505365.2
zinc finger protein 302
chr19_+_34677639 0.78 ENST00000627982.2
ENST00000613363.4
ENST00000502743.5
ENST00000509528.5
ENST00000506901.5
ENST00000457781.6
ENST00000505163.5
ENST00000505242.6
ENST00000423823.6
ENST00000507959.5
ENST00000446502.6
zinc finger protein 302
chr10_-_114684457 0.76 ENST00000392955.7
actin binding LIM protein 1
chr5_+_90899183 0.67 ENST00000640815.1
adhesion G protein-coupled receptor V1
chr6_-_111483700 0.67 ENST00000435970.5
ENST00000358835.7
REV3 like, DNA directed polymerase zeta catalytic subunit
chr3_+_171843337 0.64 ENST00000334567.9
ENST00000619900.4
ENST00000450693.1
transmembrane protein 212
chr12_-_14929116 0.63 ENST00000540097.1
endoplasmic reticulum protein 27
chr11_-_118565992 0.62 ENST00000264020.6
intraflagellar transport 46
chr19_+_34734155 0.60 ENST00000599244.5
ENST00000392232.7
ENST00000492450.3
ENST00000595708.5
ENST00000593781.5
zinc finger protein 181
chr19_-_50025936 0.58 ENST00000596445.5
ENST00000599538.5
VRK serine/threonine kinase 3
chr19_+_44165127 0.57 ENST00000590089.5
ENST00000454662.6
zinc finger protein 226
chr9_+_114611206 0.56 ENST00000374049.4
ENST00000288502.9
transmembrane protein 268
chr5_-_16508858 0.55 ENST00000684456.1
reticulophagy regulator 1
chr6_-_46921926 0.55 ENST00000283296.12
adhesion G protein-coupled receptor F5
chr5_+_90640718 0.54 ENST00000640403.1
adhesion G protein-coupled receptor V1
chr9_+_97307645 0.54 ENST00000529487.3
coiled-coil domain containing 180
chr7_-_150341615 0.53 ENST00000223271.8
ENST00000466675.5
ENST00000482669.1
ENST00000467793.5
retinoic acid receptor responder 2
chr12_-_9999176 0.52 ENST00000298527.10
ENST00000348658.4
C-type lectin domain family 1 member B
chr7_-_95596507 0.51 ENST00000005178.6
pyruvate dehydrogenase kinase 4
chr5_-_16508812 0.50 ENST00000683414.1
reticulophagy regulator 1
chr5_-_16508951 0.50 ENST00000682628.1
reticulophagy regulator 1
chr10_-_102419934 0.49 ENST00000406432.5
pleckstrin and Sec7 domain containing
chr1_+_210232776 0.49 ENST00000367012.4
SERTA domain containing 4
chr11_+_73308237 0.48 ENST00000263674.4
Rho guanine nucleotide exchange factor 17
chr5_+_36606355 0.48 ENST00000681909.1
ENST00000513903.5
ENST00000681795.1
ENST00000680125.1
ENST00000612708.5
ENST00000680232.1
ENST00000681776.1
ENST00000681926.1
ENST00000679958.1
ENST00000265113.9
ENST00000504121.5
ENST00000512374.1
ENST00000613445.5
ENST00000679983.1
solute carrier family 1 member 3
chr10_-_102419693 0.47 ENST00000611678.4
pleckstrin and Sec7 domain containing
chr12_+_57745017 0.46 ENST00000547992.5
ENST00000552816.5
ENST00000257910.8
ENST00000547472.5
tetraspanin 31
chr11_+_118304881 0.46 ENST00000528600.1
CD3e molecule
chr1_+_15236509 0.45 ENST00000683790.1
forkhead associated phosphopeptide binding domain 1
chr7_+_117480011 0.44 ENST00000649406.1
ENST00000648260.1
ENST00000003084.11
CF transmembrane conductance regulator
chr6_+_46793379 0.44 ENST00000230588.9
ENST00000611727.2
meprin A subunit alpha
chr14_-_21022494 0.44 ENST00000449431.6
NDRG family member 2
chr11_+_118304721 0.43 ENST00000361763.9
CD3e molecule
chr16_+_78022538 0.42 ENST00000651443.1
ENST00000299642.10
C-type lectin domain family 3 member A
chr14_-_21022258 0.42 ENST00000556366.5
NDRG family member 2
chr14_-_21022095 0.41 ENST00000635386.1
NDRG family member 2
chr19_-_51372686 0.40 ENST00000595217.1
natural killer cell granule protein 7
chr14_-_21022817 0.40 ENST00000554104.5
NDRG family member 2
chr6_-_49744378 0.39 ENST00000371159.8
ENST00000263045.9
cysteine rich secretory protein 3
chr6_-_32843994 0.38 ENST00000395339.7
ENST00000374882.8
proteasome 20S subunit beta 8
chr11_+_124115404 0.38 ENST00000361352.9
ENST00000449321.5
ENST00000392748.5
ENST00000392744.4
ENST00000456829.7
von Willebrand factor A domain containing 5A
chr14_-_21022432 0.37 ENST00000557633.5
NDRG family member 2
chr8_-_27611325 0.37 ENST00000523500.5
clusterin
chr16_-_46748337 0.36 ENST00000394809.9
myosin light chain kinase 3
chr14_+_73490926 0.35 ENST00000304061.8
ribosomal oxygenase 1
chr11_+_117200188 0.35 ENST00000529792.5
transgelin
chr2_+_102187015 0.33 ENST00000441515.3
ENST00000264257.7
interleukin 1 receptor like 2
chr8_-_27611424 0.33 ENST00000405140.7
clusterin
chr4_+_145619371 0.32 ENST00000649156.2
ENST00000648388.1
metabolism of cobalamin associated A
chr2_+_188292771 0.32 ENST00000359135.7
GULP PTB domain containing engulfment adaptor 1
chr7_-_93226449 0.32 ENST00000394468.7
ENST00000453812.2
HEPACAM family member 2
chr12_-_51009264 0.32 ENST00000545993.7
solute carrier family 11 member 2
chr19_-_51372640 0.31 ENST00000600427.5
ENST00000221978.10
natural killer cell granule protein 7
chrX_+_136487940 0.31 ENST00000370648.4
bombesin receptor subtype 3
chr5_+_73813518 0.30 ENST00000296799.8
Rho guanine nucleotide exchange factor 28
chr10_+_101031223 0.29 ENST00000393459.5
ENST00000224807.9
sideroflexin 3
chr2_-_79159747 0.29 ENST00000409839.7
ENST00000305165.3
ENST00000393878.5
ENST00000490901.2
regenerating family member 3 alpha
chr17_+_34356472 0.28 ENST00000225844.7
C-C motif chemokine ligand 13
chr20_+_45890236 0.27 ENST00000372484.8
ENST00000677394.1
cathepsin A
chr15_+_65550819 0.25 ENST00000569894.5
3-hydroxyacyl-CoA dehydratase 3
chr22_-_31140494 0.25 ENST00000215885.4
phospholipase A2 group III
chr6_+_52186373 0.25 ENST00000648244.1
interleukin 17A
chr18_+_6729698 0.25 ENST00000383472.9
Rho GTPase activating protein 28
chr2_-_162071183 0.24 ENST00000678668.1
dipeptidyl peptidase 4
chr20_+_19886506 0.24 ENST00000648440.1
Ras and Rab interactor 2
chr16_+_67227105 0.24 ENST00000563953.5
ENST00000304800.14
ENST00000565201.1
transmembrane protein 208
chr17_+_42980547 0.23 ENST00000361677.5
ENST00000589705.1
RUN domain containing 1
chr1_+_202462730 0.23 ENST00000290419.9
ENST00000491336.5
protein phosphatase 1 regulatory subunit 12B
chr14_-_80941719 0.23 ENST00000557411.5
ENST00000555265.6
centrosomal protein 128
chr2_+_188292814 0.23 ENST00000409580.5
ENST00000409637.7
GULP PTB domain containing engulfment adaptor 1
chr19_+_50025714 0.21 ENST00000598809.5
ENST00000595661.5
ENST00000391821.6
zinc finger protein 473
chrX_-_155334580 0.21 ENST00000369449.7
ENST00000321926.4
chloride intracellular channel 2
chr19_+_39391323 0.21 ENST00000615911.4
ENST00000315588.11
ENST00000594368.5
ENST00000596297.1
mediator complex subunit 29
chr13_+_111115303 0.21 ENST00000646102.2
ENST00000449979.5
Rho guanine nucleotide exchange factor 7
chr6_-_25874212 0.21 ENST00000361703.10
ENST00000397060.8
solute carrier family 17 member 3
chr19_+_50025989 0.20 ENST00000445728.7
ENST00000270617.8
ENST00000601364.5
zinc finger protein 473
chr6_-_27831557 0.20 ENST00000611927.2
H4 clustered histone 12
chr1_+_32362537 0.20 ENST00000373534.4
testis specific serine kinase 3
chr2_-_96035974 0.20 ENST00000434632.5
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr2_-_159616442 0.20 ENST00000541068.6
ENST00000392783.7
ENST00000392782.5
bromodomain adjacent to zinc finger domain 2B
chr14_-_20413420 0.20 ENST00000556935.5
ENST00000556549.1
ENST00000262715.10
telomerase associated protein 1
chr11_+_64291992 0.20 ENST00000394525.6
potassium two pore domain channel subfamily K member 4
chr22_+_24155797 0.19 ENST00000337989.11
calcineurin binding protein 1
chr3_-_187737943 0.19 ENST00000438077.1
BCL6 transcription repressor
chr4_-_186555567 0.19 ENST00000307161.5
melatonin receptor 1A
chr1_+_121087343 0.19 ENST00000616817.4
ENST00000623603.3
ENST00000369384.9
ENST00000369383.8
ENST00000369178.5
Fc fragment of IgG receptor Ib
chr6_+_133889105 0.18 ENST00000367882.5
transcription factor 21
chr3_-_79767987 0.18 ENST00000464233.6
roundabout guidance receptor 1
chr5_-_161546708 0.18 ENST00000393959.6
gamma-aminobutyric acid type A receptor subunit beta2
chrX_-_71255060 0.17 ENST00000373988.5
ENST00000373998.5
zinc finger MYM-type containing 3
chr19_+_10086787 0.17 ENST00000590378.5
ENST00000397881.7
shiftless antiviral inhibitor of ribosomal frameshifting
chr17_-_79950828 0.17 ENST00000572862.5
ENST00000573782.5
ENST00000574427.1
ENST00000570373.5
ENST00000340848.11
ENST00000576768.5
TBC1 domain family member 16
chr1_-_230869564 0.16 ENST00000470540.5
chromosome 1 open reading frame 198
chr19_+_44113385 0.16 ENST00000262894.11
ENST00000588926.5
ENST00000592780.5
zinc finger protein 225
chr20_-_20052389 0.16 ENST00000536226.2
crooked neck pre-mRNA splicing factor 1
chr9_-_113401249 0.16 ENST00000409155.8
ENST00000448137.5
aminolevulinate dehydratase
chr16_+_4624811 0.16 ENST00000415496.5
ENST00000262370.12
ENST00000587747.5
ENST00000399577.9
ENST00000588994.5
ENST00000586183.5
mahogunin ring finger 1
chr7_+_117480052 0.16 ENST00000426809.5
ENST00000649781.1
CF transmembrane conductance regulator
chr19_+_44094380 0.16 ENST00000336976.10
zinc finger protein 224
chr16_+_66566393 0.15 ENST00000332695.11
ENST00000336328.10
ENST00000457188.6
ENST00000528324.5
ENST00000529506.5
ENST00000531885.5
ENST00000533666.5
ENST00000533953.5
ENST00000379500.7
ENST00000328020.10
CKLF like MARVEL transmembrane domain containing 1
chr2_+_95165784 0.15 ENST00000622059.4
ENST00000614034.5
ENST00000611147.1
zinc finger protein 2
chr14_+_55661272 0.14 ENST00000555573.5
kinectin 1
chr11_-_120138104 0.14 ENST00000341846.10
tripartite motif containing 29
chr1_+_9239835 0.14 ENST00000602477.1
hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase
chr9_-_114074969 0.14 ENST00000466610.6
alpha-1-microglobulin/bikunin precursor
chr13_-_40982880 0.14 ENST00000635415.1
E74 like ETS transcription factor 1
chr3_+_122577596 0.13 ENST00000483793.5
ENST00000464300.7
poly(ADP-ribose) polymerase family member 15
chr5_+_32585549 0.13 ENST00000265073.9
ENST00000515355.5
ENST00000502897.5
ENST00000510442.1
SUB1 regulator of transcription
chr1_+_149782671 0.13 ENST00000444948.5
ENST00000369168.5
Fc fragment of IgG receptor Ia
chr4_-_139084289 0.12 ENST00000510408.5
ENST00000379549.7
ENST00000358635.7
E74 like ETS transcription factor 2
chrX_-_138711663 0.12 ENST00000315930.11
fibroblast growth factor 13
chr15_+_44728985 0.12 ENST00000559390.5
tripartite motif containing 69
chr17_-_60526167 0.11 ENST00000083182.8
amyloid beta precursor protein binding protein 2
chr18_-_7117786 0.11 ENST00000389658.4
laminin subunit alpha 1
chr17_+_3420568 0.11 ENST00000574571.4
olfactory receptor family 3 subfamily A member 3
chr15_-_65792283 0.11 ENST00000443035.8
ENST00000564674.5
DENN domain containing 4A
chr14_-_21456050 0.11 ENST00000645929.1
ENST00000646647.2
chromodomain helicase DNA binding protein 8
chr6_+_25754699 0.11 ENST00000439485.6
ENST00000377905.9
solute carrier family 17 member 4
chr19_-_10503186 0.11 ENST00000592055.2
ENST00000171111.10
kelch like ECH associated protein 1
chr17_-_5419647 0.10 ENST00000573584.6
nucleoporin 88
chr2_-_201698628 0.10 ENST00000602867.1
ENST00000409474.8
membrane palmitoylated protein 4
chr11_-_120128831 0.10 ENST00000529044.5
tripartite motif containing 29
chr17_+_46295099 0.10 ENST00000393465.7
ENST00000320254.5
leucine rich repeat containing 37A
chr3_-_52830664 0.09 ENST00000266041.9
ENST00000406595.5
ENST00000485816.5
inter-alpha-trypsin inhibitor heavy chain 4
chr1_+_232950580 0.09 ENST00000366628.10
ENST00000366627.4
nucleoside-triphosphatase, cancer-related
chr2_+_27537380 0.09 ENST00000447166.2
chromosome 2 open reading frame 16
chr12_-_54973683 0.09 ENST00000532804.5
ENST00000531122.5
ENST00000533446.5
thymocyte expressed, positive selection associated 1
chr21_+_34364003 0.09 ENST00000290310.4
potassium voltage-gated channel subfamily E regulatory subunit 2
chr12_-_11022620 0.08 ENST00000390673.2
taste 2 receptor member 19
chr6_-_166167832 0.08 ENST00000366876.7
T-box transcription factor T
chr4_+_129096144 0.08 ENST00000425929.6
ENST00000508622.1
chromosome 4 open reading frame 33
chr6_+_108656346 0.08 ENST00000540898.1
forkhead box O3
chr12_+_20695323 0.08 ENST00000266509.7
solute carrier organic anion transporter family member 1C1
chrX_+_150693360 0.08 ENST00000370390.7
ENST00000490316.6
ENST00000542156.5
ENST00000445323.7
myotubularin related protein 1
chr12_-_48852153 0.08 ENST00000308025.8
DEAD-box helicase 23
chr2_-_201698692 0.07 ENST00000315506.11
ENST00000359962.9
ENST00000620095.4
membrane palmitoylated protein 4
chr20_+_8132138 0.07 ENST00000378641.7
ENST00000338037.11
ENST00000629992.2
phospholipase C beta 1
chr1_+_40531573 0.07 ENST00000648542.1
ENST00000372699.8
ENST00000372696.3
ENST00000372697.7
zinc finger protein 684
chr6_-_56851888 0.07 ENST00000312431.10
ENST00000520645.5
dystonin
chr1_-_7940825 0.07 ENST00000377507.8
TNF receptor superfamily member 9
chr15_+_57706725 0.07 ENST00000380557.4
ENST00000649091.1
RNA polymerase II subunit M
chr12_-_91004965 0.06 ENST00000261172.8
epiphycan
chr16_+_85899121 0.06 ENST00000268638.10
ENST00000565552.1
interferon regulatory factor 8
chr4_-_139556199 0.06 ENST00000274031.8
ENST00000506866.6
SET domain containing 7, histone lysine methyltransferase
chr5_-_161546970 0.06 ENST00000675303.1
gamma-aminobutyric acid type A receptor subunit beta2
chr15_+_57706670 0.06 ENST00000299638.8
RNA polymerase II subunit M
chr10_+_17752185 0.06 ENST00000377495.2
transmembrane protein 236
chr20_+_41028814 0.05 ENST00000361337.3
DNA topoisomerase I
chr4_-_76036060 0.05 ENST00000306621.8
C-X-C motif chemokine ligand 11
chr13_-_45341086 0.05 ENST00000309246.9
ENST00000379060.8
ENST00000379055.5
ENST00000527226.2
ENST00000530705.6
ENST00000379056.5
ENST00000616577.4
tumor protein, translationally-controlled 1
chr2_-_201698040 0.05 ENST00000396886.7
ENST00000409143.5
membrane palmitoylated protein 4
chr3_+_45388555 0.05 ENST00000650792.2
ENST00000414984.5
ENST00000645846.2
leucyl-tRNA synthetase 2, mitochondrial
chr1_-_230745574 0.05 ENST00000681269.1
angiotensinogen
chr11_-_85627268 0.05 ENST00000650630.1
discs large MAGUK scaffold protein 2
chr14_+_69191760 0.05 ENST00000409949.5
ENST00000312994.9
ENST00000409242.5
ENST00000413191.1
exonuclease 3'-5' domain containing 2
chr14_+_24161257 0.05 ENST00000396864.8
ENST00000557894.5
ENST00000559284.5
ENST00000560275.5
interferon regulatory factor 9
chr17_-_48545077 0.04 ENST00000330070.6
homeobox B2
chr16_-_18926408 0.04 ENST00000446231.7
SMG1 nonsense mediated mRNA decay associated PI3K related kinase
chr7_-_83649097 0.04 ENST00000643230.2
semaphorin 3E
chr7_-_108528155 0.04 ENST00000453085.1
patatin like phospholipase domain containing 8
chr3_+_122680802 0.04 ENST00000474629.7
poly(ADP-ribose) polymerase family member 14
chr12_+_20695553 0.03 ENST00000545102.1
solute carrier organic anion transporter family member 1C1
chr19_+_17337539 0.03 ENST00000324894.13
ENST00000358792.11
ENST00000600625.5
GTP binding protein 3, mitochondrial
chr14_-_24634160 0.03 ENST00000616551.1
ENST00000382542.5
ENST00000216341.9
ENST00000526004.1
ENST00000415355.7
granzyme B
chr3_+_130345516 0.03 ENST00000265379.10
collagen type VI alpha 5 chain
chr8_-_42501224 0.02 ENST00000520262.6
ENST00000517366.1
solute carrier family 20 member 2
chr12_+_70242984 0.02 ENST00000547780.5
ENST00000418359.7
CCR4-NOT transcription complex subunit 2
chr6_+_30888672 0.02 ENST00000446312.5
discoidin domain receptor tyrosine kinase 1
chrX_+_101391202 0.02 ENST00000471855.1
ribosomal protein L36a
chr5_+_141343818 0.02 ENST00000619750.1
ENST00000253812.8
protocadherin gamma subfamily A, 3
chr7_-_83162899 0.02 ENST00000423517.6
piccolo presynaptic cytomatrix protein
chr4_-_46124046 0.02 ENST00000295452.5
gamma-aminobutyric acid type A receptor subunit gamma1
chr19_+_35282520 0.02 ENST00000222304.5
hepcidin antimicrobial peptide
chr3_+_77039836 0.02 ENST00000461745.5
roundabout guidance receptor 2
chr5_-_161546671 0.01 ENST00000517547.5
gamma-aminobutyric acid type A receptor subunit beta2
chr2_+_233917371 0.01 ENST00000324695.9
ENST00000433712.6
transient receptor potential cation channel subfamily M member 8
chr13_-_26221703 0.01 ENST00000381570.7
ENST00000346166.7
ring finger protein 6
chrX_-_108091520 0.01 ENST00000340200.5
ENST00000217958.8
ENST00000372296.5
ENST00000372295.5
ENST00000361815.9
proteasome 26S subunit, non-ATPase 10
chr12_+_5432101 0.01 ENST00000423158.4
neurotrophin 3
chr19_+_10086305 0.01 ENST00000253110.16
ENST00000591813.5
shiftless antiviral inhibitor of ribosomal frameshifting
chr19_-_39391137 0.01 ENST00000595564.5
PAF1 homolog, Paf1/RNA polymerase II complex component
chr10_+_102644887 0.01 ENST00000462202.3
tripartite motif containing 8
chrX_+_106802660 0.01 ENST00000357242.10
ENST00000310452.6
ENST00000481617.6
ENST00000276175.7
TBC1 domain family member 8B

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0061570 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.3 2.8 GO:0061709 reticulophagy(GO:0061709)
0.2 0.9 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.2 0.6 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.1 0.7 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.4 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 2.0 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 1.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.5 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.3 GO:1905237 response to cyclosporin A(GO:1905237)
0.1 0.1 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.1 0.3 GO:0030961 peptidyl-arginine hydroxylation(GO:0030961)
0.1 0.3 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.2 GO:0071284 cellular response to lead ion(GO:0071284)
0.1 0.2 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.1 0.3 GO:0015692 lead ion transport(GO:0015692)
0.1 0.2 GO:0072276 branchiomeric skeletal muscle development(GO:0014707) bronchiole development(GO:0060435) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.1 1.4 GO:0006825 copper ion transport(GO:0006825)
0.1 0.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.2 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.5 GO:0006537 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.5 GO:0071073 surfactant homeostasis(GO:0043129) positive regulation of phospholipid biosynthetic process(GO:0071073)
0.0 0.1 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.5 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.3 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 1.0 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.5 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.3 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.1 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.0 0.2 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716) psychomotor behavior(GO:0036343)
0.0 0.3 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.1 GO:0090427 activation of meiosis(GO:0090427)
0.0 0.3 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.2 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.2 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.6 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 2.0 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.7 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 4.1 GO:0044782 cilium organization(GO:0044782)
0.0 2.7 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 1.4 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.8 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.0 0.0 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.1 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 1.2 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 1.3 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.5 GO:0030220 platelet formation(GO:0030220)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.0 0.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.3 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.0 GO:0021569 rhombomere 3 development(GO:0021569)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.6 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 0.7 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 1.2 GO:0097433 dense body(GO:0097433)
0.1 0.9 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.3 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.7 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 2.8 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.3 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 1.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.2 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 3.9 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581) invadopodium membrane(GO:0071438)
0.0 1.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0004522 ribonuclease A activity(GO:0004522)
0.2 1.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 0.6 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.2 1.4 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.8 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.1 0.5 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.3 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 2.1 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.3 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.9 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.2 GO:0097604 temperature-gated cation channel activity(GO:0097604)
0.1 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.3 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0102345 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 1.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.7 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.2 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.3 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 0.3 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 1.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.2 GO:0034061 DNA polymerase activity(GO:0034061)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 1.0 PID IL23 PATHWAY IL23-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.9 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 1.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 2.3 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 1.4 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels