Project
Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
Navigation
Downloads
Results for TAL1
Z-value: 1.01
Motif logo
Transcription factors associated with TAL1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| TAL1 | hg38_v1_chr1_-_47231715_47231786 | -0.08 | 6.7e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of TAL1
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr16_-_55833186 Show fit | 2.24 |
ENST00000361503.8
ENST00000422046.6 |
carboxylesterase 1 |
|
| chr4_+_74933095 Show fit | 2.05 |
ENST00000513238.5
|
prostate androgen-regulated mucin-like protein 1 |
|
| chr16_-_55833085 Show fit | 1.99 |
ENST00000360526.8
|
carboxylesterase 1 |
|
| chr17_-_41124178 Show fit | 1.81 |
ENST00000394014.2
|
keratin associated protein 4-12 |
|
| chr1_+_78490966 Show fit | 1.81 |
ENST00000370757.8
ENST00000370756.3 |
prostaglandin F receptor |
|
| chr4_-_16083714 Show fit | 1.74 |
ENST00000508167.5
|
prominin 1 |
|
| chr4_-_16083695 Show fit | 1.71 |
ENST00000510224.5
|
prominin 1 |
|
| chr4_+_74933108 Show fit | 1.57 |
ENST00000307428.7
|
prostate androgen-regulated mucin-like protein 1 |
|
| chr6_-_24910695 Show fit | 1.52 |
ENST00000643623.1
ENST00000538035.6 ENST00000647136.1 |
RHO family interacting cell polarization regulator 2 |
|
| chr6_-_24911029 Show fit | 1.50 |
ENST00000259698.9
ENST00000644621.1 ENST00000644411.1 |
RHO family interacting cell polarization regulator 2 |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 4.9 | GO:2000768 | positive regulation of nephron tubule epithelial cell differentiation(GO:2000768) |
| 1.1 | 4.2 | GO:0090119 | vesicle-mediated cholesterol transport(GO:0090119) |
| 0.8 | 4.2 | GO:1903904 | negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107) |
| 0.1 | 3.6 | GO:0044458 | motile cilium assembly(GO:0044458) |
| 0.0 | 3.0 | GO:0051973 | positive regulation of telomerase activity(GO:0051973) |
| 0.0 | 2.9 | GO:0006953 | acute-phase response(GO:0006953) |
| 0.1 | 2.6 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
| 0.1 | 2.6 | GO:0015991 | ATP hydrolysis coupled proton transport(GO:0015991) |
| 0.0 | 2.6 | GO:0007223 | Wnt signaling pathway, calcium modulating pathway(GO:0007223) |
| 0.2 | 2.4 | GO:0043985 | histone H4-R3 methylation(GO:0043985) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 8.6 | GO:0005930 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.0 | 7.6 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.2 | 4.3 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.4 | 4.2 | GO:0060171 | stereocilium membrane(GO:0060171) |
| 0.2 | 4.1 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.0 | 3.7 | GO:0036064 | ciliary basal body(GO:0036064) |
| 0.0 | 3.1 | GO:0045095 | keratin filament(GO:0045095) |
| 0.0 | 3.1 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.0 | 2.7 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 2.6 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.5 | GO:0042805 | actinin binding(GO:0042805) |
| 0.2 | 4.1 | GO:0008392 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 0.8 | 4.0 | GO:0047374 | methylumbelliferyl-acetate deacetylase activity(GO:0047374) |
| 0.1 | 3.9 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.5 | 3.5 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.2 | 2.7 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
| 0.0 | 2.6 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.0 | 2.4 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.0 | 2.2 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.1 | 2.0 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 4.0 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.0 | 3.2 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 2.5 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 2.4 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.0 | 2.0 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.0 | 2.0 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.0 | 1.8 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 0.0 | 1.6 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.0 | 1.6 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 1.2 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.8 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.1 | 3.2 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.1 | 2.9 | REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 0.0 | 2.9 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.2 | 2.6 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 0.0 | 2.6 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.0 | 2.5 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 2.5 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.1 | 2.4 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.0 | 2.2 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |