Project
Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
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Results for TBP
Z-value: 1.77
Motif logo
Transcription factors associated with TBP
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
TBP
|
ENSG00000112592.14 | TBP |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| TBP | hg38_v1_chr6_+_170554333_170554396 | 0.19 | 3.1e-01 | Click! |
Activity profile of TBP motif
Sorted Z-values of TBP motif
Network of associatons between targets according to the STRING database.
First level regulatory network of TBP
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 4.1 | GO:0042270 | protection from natural killer cell mediated cytotoxicity(GO:0042270) |
| 1.3 | 7.8 | GO:0060356 | leucine import(GO:0060356) |
| 1.1 | 3.4 | GO:0060279 | positive regulation of ovulation(GO:0060279) |
| 1.1 | 6.7 | GO:0002225 | positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803) |
| 1.1 | 4.2 | GO:0045065 | cytotoxic T cell differentiation(GO:0045065) |
| 1.0 | 4.2 | GO:0060474 | positive regulation of sperm motility involved in capacitation(GO:0060474) |
| 1.0 | 4.1 | GO:0018199 | peptidyl-glutamine modification(GO:0018199) |
| 1.0 | 3.1 | GO:1904956 | regulation of midbrain dopaminergic neuron differentiation(GO:1904956) |
| 1.0 | 3.0 | GO:0036388 | pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299) |
| 0.9 | 2.6 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
| 0.8 | 3.9 | GO:0097368 | establishment of Sertoli cell barrier(GO:0097368) |
| 0.8 | 2.3 | GO:0060032 | notochord regression(GO:0060032) |
| 0.6 | 2.4 | GO:0018101 | protein citrullination(GO:0018101) histone citrullination(GO:0036414) |
| 0.6 | 5.3 | GO:2000332 | response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334) |
| 0.5 | 4.4 | GO:0015705 | iodide transport(GO:0015705) |
| 0.5 | 1.6 | GO:1903015 | regulation of exo-alpha-sialidase activity(GO:1903015) |
| 0.5 | 1.4 | GO:0070512 | regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512) |
| 0.5 | 5.9 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
| 0.5 | 1.8 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
| 0.4 | 2.7 | GO:1900019 | regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020) |
| 0.4 | 1.7 | GO:0003430 | growth plate cartilage chondrocyte growth(GO:0003430) |
| 0.4 | 1.3 | GO:0086092 | regulation of the force of heart contraction by cardiac conduction(GO:0086092) positive regulation of calcium:sodium antiporter activity(GO:1903281) |
| 0.4 | 2.0 | GO:1904636 | miRNA catabolic process(GO:0010587) negative regulation by host of viral genome replication(GO:0044828) response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637) |
| 0.4 | 1.2 | GO:0090031 | positive regulation of steroid hormone biosynthetic process(GO:0090031) |
| 0.4 | 2.7 | GO:2000852 | regulation of corticosterone secretion(GO:2000852) |
| 0.4 | 0.8 | GO:0060298 | positive regulation of sarcomere organization(GO:0060298) |
| 0.4 | 0.4 | GO:0070093 | negative regulation of glucagon secretion(GO:0070093) |
| 0.4 | 1.5 | GO:0002541 | activation of plasma proteins involved in acute inflammatory response(GO:0002541) |
| 0.4 | 1.5 | GO:0010897 | negative regulation of triglyceride catabolic process(GO:0010897) |
| 0.4 | 0.7 | GO:0010693 | negative regulation of alkaline phosphatase activity(GO:0010693) |
| 0.4 | 3.5 | GO:0060426 | lung vasculature development(GO:0060426) |
| 0.3 | 3.5 | GO:0051005 | negative regulation of lipoprotein lipase activity(GO:0051005) |
| 0.3 | 1.7 | GO:0090131 | mesenchyme migration(GO:0090131) |
| 0.3 | 0.7 | GO:0060621 | negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910) |
| 0.3 | 2.9 | GO:0001661 | conditioned taste aversion(GO:0001661) |
| 0.3 | 5.7 | GO:2001135 | regulation of endocytic recycling(GO:2001135) |
| 0.3 | 1.1 | GO:1990168 | protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168) |
| 0.3 | 1.4 | GO:0044240 | multicellular organism lipid catabolic process(GO:0044240) |
| 0.3 | 0.8 | GO:0006059 | hexitol metabolic process(GO:0006059) |
| 0.3 | 1.9 | GO:0055064 | chloride ion homeostasis(GO:0055064) |
| 0.3 | 0.8 | GO:0051039 | histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039) |
| 0.3 | 0.8 | GO:0021526 | medial motor column neuron differentiation(GO:0021526) |
| 0.3 | 0.8 | GO:0044691 | tooth eruption(GO:0044691) |
| 0.3 | 2.0 | GO:0002318 | myeloid progenitor cell differentiation(GO:0002318) |
| 0.2 | 1.2 | GO:0007343 | egg activation(GO:0007343) |
| 0.2 | 15.2 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.2 | 0.7 | GO:0048560 | establishment of anatomical structure orientation(GO:0048560) |
| 0.2 | 1.0 | GO:0055011 | atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014) |
| 0.2 | 0.7 | GO:1901492 | positive regulation of lymphangiogenesis(GO:1901492) |
| 0.2 | 0.7 | GO:2000097 | regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
| 0.2 | 3.2 | GO:0045091 | regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091) |
| 0.2 | 2.0 | GO:0046689 | response to mercury ion(GO:0046689) |
| 0.2 | 0.7 | GO:0005988 | lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989) |
| 0.2 | 3.9 | GO:0001542 | ovulation from ovarian follicle(GO:0001542) |
| 0.2 | 1.1 | GO:0035948 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) |
| 0.2 | 1.4 | GO:1904338 | regulation of dopaminergic neuron differentiation(GO:1904338) |
| 0.2 | 4.6 | GO:0045109 | intermediate filament organization(GO:0045109) |
| 0.2 | 0.6 | GO:1990641 | response to iron ion starvation(GO:1990641) |
| 0.2 | 1.1 | GO:0038030 | non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) |
| 0.2 | 4.5 | GO:0006346 | methylation-dependent chromatin silencing(GO:0006346) |
| 0.2 | 4.9 | GO:0048240 | sperm capacitation(GO:0048240) |
| 0.2 | 2.9 | GO:1903764 | regulation of potassium ion export across plasma membrane(GO:1903764) |
| 0.2 | 0.7 | GO:0031064 | negative regulation of histone deacetylation(GO:0031064) |
| 0.2 | 7.0 | GO:0046688 | response to copper ion(GO:0046688) |
| 0.2 | 0.2 | GO:0051795 | positive regulation of catagen(GO:0051795) |
| 0.2 | 0.5 | GO:0002728 | negative regulation of natural killer cell cytokine production(GO:0002728) |
| 0.2 | 0.5 | GO:0015670 | carbon dioxide transport(GO:0015670) |
| 0.2 | 0.8 | GO:0007161 | calcium-independent cell-matrix adhesion(GO:0007161) |
| 0.2 | 2.5 | GO:0003417 | growth plate cartilage development(GO:0003417) |
| 0.2 | 0.8 | GO:1904222 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222) |
| 0.2 | 0.5 | GO:0021524 | visceral motor neuron differentiation(GO:0021524) |
| 0.1 | 1.5 | GO:0097646 | calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
| 0.1 | 0.7 | GO:0035986 | senescence-associated heterochromatin focus assembly(GO:0035986) |
| 0.1 | 1.1 | GO:0002018 | renin-angiotensin regulation of aldosterone production(GO:0002018) |
| 0.1 | 1.6 | GO:0018401 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) |
| 0.1 | 0.8 | GO:1904627 | response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628) |
| 0.1 | 3.2 | GO:0071294 | cellular response to zinc ion(GO:0071294) |
| 0.1 | 4.2 | GO:0007398 | ectoderm development(GO:0007398) |
| 0.1 | 1.4 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.1 | 0.5 | GO:0035519 | protein K29-linked ubiquitination(GO:0035519) |
| 0.1 | 0.2 | GO:1990535 | neuron projection maintenance(GO:1990535) |
| 0.1 | 1.3 | GO:0046104 | thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125) |
| 0.1 | 1.8 | GO:0098870 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.1 | 0.5 | GO:0051710 | cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710) |
| 0.1 | 0.5 | GO:0060460 | left lung development(GO:0060459) left lung morphogenesis(GO:0060460) |
| 0.1 | 1.3 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
| 0.1 | 2.9 | GO:0055003 | cardiac myofibril assembly(GO:0055003) |
| 0.1 | 0.9 | GO:0035879 | plasma membrane lactate transport(GO:0035879) |
| 0.1 | 0.4 | GO:0086073 | bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073) |
| 0.1 | 0.9 | GO:0006729 | tetrahydrobiopterin biosynthetic process(GO:0006729) regulation of lung blood pressure(GO:0014916) tetrahydrobiopterin metabolic process(GO:0046146) |
| 0.1 | 0.3 | GO:0061394 | regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) |
| 0.1 | 1.1 | GO:2000400 | positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400) |
| 0.1 | 0.3 | GO:0071603 | endothelial cell-cell adhesion(GO:0071603) |
| 0.1 | 0.3 | GO:0097477 | lateral motor column neuron migration(GO:0097477) |
| 0.1 | 0.4 | GO:0006617 | SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617) |
| 0.1 | 0.2 | GO:0046878 | positive regulation of saliva secretion(GO:0046878) |
| 0.1 | 1.4 | GO:0032119 | sequestering of zinc ion(GO:0032119) |
| 0.1 | 0.4 | GO:0090214 | spongiotrophoblast layer developmental growth(GO:0090214) |
| 0.1 | 0.3 | GO:0035262 | gonad morphogenesis(GO:0035262) |
| 0.1 | 2.2 | GO:0033141 | positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141) |
| 0.1 | 0.3 | GO:1901899 | positive regulation of relaxation of cardiac muscle(GO:1901899) |
| 0.1 | 0.7 | GO:0043587 | tongue morphogenesis(GO:0043587) |
| 0.1 | 6.7 | GO:0006953 | acute-phase response(GO:0006953) |
| 0.1 | 1.4 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
| 0.1 | 0.6 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
| 0.1 | 0.6 | GO:0009438 | methylglyoxal metabolic process(GO:0009438) |
| 0.1 | 0.7 | GO:0045617 | negative regulation of keratinocyte differentiation(GO:0045617) |
| 0.1 | 0.4 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
| 0.1 | 0.3 | GO:0048058 | compound eye corneal lens development(GO:0048058) |
| 0.1 | 0.9 | GO:0010727 | negative regulation of hydrogen peroxide metabolic process(GO:0010727) |
| 0.1 | 0.3 | GO:0035910 | ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) |
| 0.1 | 0.5 | GO:0001692 | histamine metabolic process(GO:0001692) |
| 0.1 | 0.3 | GO:0001983 | regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) |
| 0.1 | 0.3 | GO:0002881 | negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881) |
| 0.1 | 1.6 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.1 | 0.5 | GO:0060017 | parathyroid gland development(GO:0060017) |
| 0.1 | 0.3 | GO:0061073 | ciliary body morphogenesis(GO:0061073) |
| 0.1 | 0.7 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 0.1 | 0.9 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
| 0.1 | 0.8 | GO:0035585 | calcium-mediated signaling using extracellular calcium source(GO:0035585) |
| 0.1 | 0.2 | GO:2000547 | regulation of dendritic cell dendrite assembly(GO:2000547) |
| 0.1 | 0.2 | GO:0014016 | neuroblast differentiation(GO:0014016) |
| 0.1 | 0.2 | GO:0045876 | positive regulation of sister chromatid cohesion(GO:0045876) |
| 0.1 | 0.2 | GO:0098507 | polynucleotide 5' dephosphorylation(GO:0098507) |
| 0.1 | 0.4 | GO:0038169 | somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170) |
| 0.1 | 0.6 | GO:0090232 | positive regulation of spindle checkpoint(GO:0090232) |
| 0.1 | 0.3 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 0.1 | 0.7 | GO:2000344 | positive regulation of acrosome reaction(GO:2000344) |
| 0.1 | 0.6 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.1 | 0.3 | GO:0002501 | peptide antigen assembly with MHC protein complex(GO:0002501) |
| 0.1 | 6.6 | GO:0070268 | cornification(GO:0070268) |
| 0.1 | 0.8 | GO:0032071 | regulation of endodeoxyribonuclease activity(GO:0032071) |
| 0.1 | 3.7 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.1 | 0.3 | GO:0009635 | response to herbicide(GO:0009635) |
| 0.1 | 0.9 | GO:0035457 | cellular response to interferon-alpha(GO:0035457) |
| 0.1 | 1.7 | GO:0090023 | positive regulation of neutrophil chemotaxis(GO:0090023) |
| 0.1 | 0.4 | GO:0033133 | positive regulation of glucokinase activity(GO:0033133) |
| 0.1 | 1.1 | GO:0080111 | DNA demethylation(GO:0080111) |
| 0.1 | 0.3 | GO:1900005 | positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573) |
| 0.1 | 0.5 | GO:0042904 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
| 0.1 | 0.6 | GO:0070166 | enamel mineralization(GO:0070166) |
| 0.1 | 1.0 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
| 0.1 | 0.4 | GO:0060054 | positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054) |
| 0.1 | 0.1 | GO:1902688 | regulation of NAD metabolic process(GO:1902688) |
| 0.1 | 0.3 | GO:0042421 | norepinephrine biosynthetic process(GO:0042421) |
| 0.1 | 2.0 | GO:0060325 | face morphogenesis(GO:0060325) |
| 0.0 | 0.6 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.0 | 0.4 | GO:0061737 | leukotriene signaling pathway(GO:0061737) |
| 0.0 | 1.5 | GO:0006706 | steroid catabolic process(GO:0006706) |
| 0.0 | 1.0 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.0 | 0.7 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
| 0.0 | 0.5 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.0 | 0.1 | GO:1900738 | positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) |
| 0.0 | 0.1 | GO:0002874 | regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) |
| 0.0 | 0.2 | GO:0099640 | axo-dendritic protein transport(GO:0099640) |
| 0.0 | 0.2 | GO:0000270 | peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253) |
| 0.0 | 1.8 | GO:0070884 | regulation of calcineurin-NFAT signaling cascade(GO:0070884) |
| 0.0 | 0.3 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
| 0.0 | 0.3 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 0.0 | 0.6 | GO:0010818 | T cell chemotaxis(GO:0010818) |
| 0.0 | 0.4 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
| 0.0 | 0.1 | GO:0000023 | maltose metabolic process(GO:0000023) |
| 0.0 | 0.7 | GO:0030261 | chromosome condensation(GO:0030261) |
| 0.0 | 0.3 | GO:0006537 | glutamate biosynthetic process(GO:0006537) |
| 0.0 | 1.4 | GO:0034080 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 0.0 | 0.4 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.0 | 0.2 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
| 0.0 | 0.1 | GO:0046968 | peptide antigen transport(GO:0046968) |
| 0.0 | 1.3 | GO:0019433 | triglyceride catabolic process(GO:0019433) |
| 0.0 | 0.7 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.0 | 0.4 | GO:1903003 | positive regulation of protein deubiquitination(GO:1903003) |
| 0.0 | 0.3 | GO:0042048 | olfactory behavior(GO:0042048) |
| 0.0 | 0.9 | GO:0039703 | viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) |
| 0.0 | 0.1 | GO:0002125 | maternal aggressive behavior(GO:0002125) |
| 0.0 | 1.0 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.0 | 0.3 | GO:0098887 | neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) |
| 0.0 | 1.2 | GO:0035767 | endothelial cell chemotaxis(GO:0035767) |
| 0.0 | 0.1 | GO:0030718 | germ-line stem cell population maintenance(GO:0030718) |
| 0.0 | 0.9 | GO:0008334 | histone mRNA metabolic process(GO:0008334) |
| 0.0 | 0.3 | GO:0039536 | negative regulation of RIG-I signaling pathway(GO:0039536) |
| 0.0 | 0.4 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.0 | 3.3 | GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154) |
| 0.0 | 1.4 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 1.5 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.0 | 0.2 | GO:0000972 | transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972) |
| 0.0 | 1.9 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.0 | 0.1 | GO:0035962 | response to interleukin-13(GO:0035962) |
| 0.0 | 1.3 | GO:0051489 | regulation of filopodium assembly(GO:0051489) |
| 0.0 | 0.4 | GO:0045324 | late endosome to vacuole transport(GO:0045324) |
| 0.0 | 0.4 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
| 0.0 | 0.5 | GO:0035589 | G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589) |
| 0.0 | 1.4 | GO:0030049 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 0.0 | 0.7 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
| 0.0 | 2.4 | GO:0060337 | type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357) |
| 0.0 | 2.8 | GO:0006024 | glycosaminoglycan biosynthetic process(GO:0006024) |
| 0.0 | 0.4 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.0 | 0.7 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.0 | 0.2 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 0.0 | 0.5 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
| 0.0 | 0.1 | GO:0042427 | serotonin biosynthetic process(GO:0042427) |
| 0.0 | 0.1 | GO:0010536 | positive regulation of activation of Janus kinase activity(GO:0010536) |
| 0.0 | 0.2 | GO:0050957 | equilibrioception(GO:0050957) |
| 0.0 | 0.3 | GO:0030157 | pancreatic juice secretion(GO:0030157) |
| 0.0 | 0.1 | GO:0061624 | fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) |
| 0.0 | 0.5 | GO:0033119 | negative regulation of RNA splicing(GO:0033119) |
| 0.0 | 1.1 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 0.0 | 0.1 | GO:0007056 | spindle assembly involved in female meiosis(GO:0007056) |
| 0.0 | 0.3 | GO:0007530 | sex determination(GO:0007530) |
| 0.0 | 1.6 | GO:0000724 | double-strand break repair via homologous recombination(GO:0000724) |
| 0.0 | 0.2 | GO:0061436 | establishment of skin barrier(GO:0061436) |
| 0.0 | 1.4 | GO:0016575 | histone deacetylation(GO:0016575) |
| 0.0 | 0.7 | GO:0006198 | cAMP catabolic process(GO:0006198) |
| 0.0 | 0.3 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.0 | 0.1 | GO:0090191 | negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191) |
| 0.0 | 0.5 | GO:0009435 | NAD biosynthetic process(GO:0009435) |
| 0.0 | 0.4 | GO:0097120 | receptor localization to synapse(GO:0097120) |
| 0.0 | 0.1 | GO:0043126 | regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128) |
| 0.0 | 0.4 | GO:0045124 | regulation of bone resorption(GO:0045124) |
| 0.0 | 0.7 | GO:0050829 | defense response to Gram-negative bacterium(GO:0050829) |
| 0.0 | 0.5 | GO:0014047 | glutamate secretion(GO:0014047) |
| 0.0 | 1.0 | GO:0045669 | positive regulation of osteoblast differentiation(GO:0045669) |
| 0.0 | 0.5 | GO:0033260 | nuclear DNA replication(GO:0033260) |
| 0.0 | 0.3 | GO:0051290 | protein heterotetramerization(GO:0051290) |
| 0.0 | 0.1 | GO:0030199 | collagen fibril organization(GO:0030199) |
| 0.0 | 0.1 | GO:0032100 | positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100) |
| 0.0 | 0.3 | GO:0071425 | hematopoietic stem cell proliferation(GO:0071425) |
| 0.0 | 0.1 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.0 | 0.1 | GO:0045950 | regulation of mitotic recombination(GO:0000019) negative regulation of mitotic recombination(GO:0045950) |
| 0.0 | 1.1 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.0 | 0.4 | GO:0040019 | positive regulation of embryonic development(GO:0040019) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 5.0 | GO:0097229 | sperm end piece(GO:0097229) |
| 1.1 | 3.4 | GO:0043511 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
| 1.0 | 4.2 | GO:1990742 | microvesicle(GO:1990742) |
| 1.0 | 3.0 | GO:0005656 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
| 1.0 | 6.9 | GO:0097209 | epidermal lamellar body(GO:0097209) |
| 0.5 | 1.6 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
| 0.5 | 1.4 | GO:0030849 | X chromosome(GO:0000805) autosome(GO:0030849) |
| 0.4 | 1.8 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.4 | 2.9 | GO:0035976 | AP1 complex(GO:0035976) |
| 0.4 | 2.2 | GO:0020018 | ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018) |
| 0.3 | 16.7 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.3 | 3.6 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.3 | 1.4 | GO:0031436 | BRCA1-BARD1 complex(GO:0031436) |
| 0.3 | 0.8 | GO:0034677 | integrin alpha7-beta1 complex(GO:0034677) |
| 0.3 | 1.6 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.2 | 2.0 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 0.2 | 1.9 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 0.2 | 2.0 | GO:0030057 | desmosome(GO:0030057) |
| 0.2 | 0.8 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 0.1 | 1.0 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.1 | 5.3 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.1 | 0.9 | GO:0034715 | pICln-Sm protein complex(GO:0034715) |
| 0.1 | 5.8 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.1 | 0.4 | GO:0044753 | amphisome(GO:0044753) |
| 0.1 | 0.4 | GO:0034271 | phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272) |
| 0.1 | 2.3 | GO:0035748 | myelin sheath abaxonal region(GO:0035748) |
| 0.1 | 0.3 | GO:1990590 | ATF1-ATF4 transcription factor complex(GO:1990590) |
| 0.1 | 0.1 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
| 0.1 | 0.5 | GO:0071942 | XPC complex(GO:0071942) |
| 0.1 | 0.7 | GO:0043196 | varicosity(GO:0043196) |
| 0.1 | 0.8 | GO:0001939 | female pronucleus(GO:0001939) |
| 0.1 | 0.4 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
| 0.1 | 0.6 | GO:0000243 | commitment complex(GO:0000243) |
| 0.1 | 0.7 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.1 | 1.4 | GO:0042589 | zymogen granule membrane(GO:0042589) |
| 0.1 | 3.7 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.1 | 0.6 | GO:0045179 | apical cortex(GO:0045179) |
| 0.1 | 0.8 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.1 | 9.8 | GO:0005604 | basement membrane(GO:0005604) |
| 0.1 | 4.0 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.1 | 1.3 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.1 | 0.5 | GO:0097451 | glial limiting end-foot(GO:0097451) |
| 0.1 | 2.9 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.1 | 1.4 | GO:0010369 | chromocenter(GO:0010369) |
| 0.1 | 10.8 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.1 | 1.1 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.1 | 0.5 | GO:0097452 | GAIT complex(GO:0097452) |
| 0.1 | 0.2 | GO:0000798 | nuclear cohesin complex(GO:0000798) |
| 0.1 | 0.3 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
| 0.1 | 0.7 | GO:0034464 | BBSome(GO:0034464) |
| 0.1 | 2.3 | GO:0097546 | ciliary base(GO:0097546) |
| 0.1 | 0.6 | GO:0042583 | chromaffin granule(GO:0042583) |
| 0.1 | 2.0 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.1 | 1.3 | GO:0090533 | cation-transporting ATPase complex(GO:0090533) |
| 0.0 | 0.8 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.0 | 1.5 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
| 0.0 | 0.2 | GO:0030895 | apolipoprotein B mRNA editing enzyme complex(GO:0030895) |
| 0.0 | 0.3 | GO:0005579 | membrane attack complex(GO:0005579) |
| 0.0 | 0.4 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.0 | 6.9 | GO:0048770 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.0 | 0.8 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.0 | 0.3 | GO:0098845 | postsynaptic endosome(GO:0098845) |
| 0.0 | 0.4 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 0.0 | 0.9 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.0 | 1.2 | GO:0031904 | endosome lumen(GO:0031904) |
| 0.0 | 0.3 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) MHC class I peptide loading complex(GO:0042824) |
| 0.0 | 0.2 | GO:0042643 | actomyosin, actin portion(GO:0042643) |
| 0.0 | 1.0 | GO:0097381 | photoreceptor disc membrane(GO:0097381) |
| 0.0 | 0.4 | GO:0036057 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.0 | 0.7 | GO:0000786 | nucleosome(GO:0000786) |
| 0.0 | 1.5 | GO:0005771 | multivesicular body(GO:0005771) |
| 0.0 | 0.1 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 0.0 | 0.3 | GO:0016013 | syntrophin complex(GO:0016013) |
| 0.0 | 0.3 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.0 | 0.6 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.0 | 0.4 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.0 | 1.6 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 1.7 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 0.2 | GO:0070449 | elongin complex(GO:0070449) |
| 0.0 | 0.1 | GO:0005863 | striated muscle myosin thick filament(GO:0005863) |
| 0.0 | 1.4 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.0 | 2.1 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 0.2 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.0 | 1.8 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 1.8 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 0.6 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.0 | 0.2 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.0 | 1.2 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
| 0.0 | 0.3 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.0 | 0.4 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.0 | 2.6 | GO:0005795 | Golgi stack(GO:0005795) |
| 0.0 | 1.4 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 0.4 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 0.0 | 0.8 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 0.5 | GO:0005921 | gap junction(GO:0005921) |
| 0.0 | 2.4 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 0.4 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.0 | 0.2 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.0 | 2.3 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.0 | 0.3 | GO:0044298 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 4.2 | GO:0031731 | CCR6 chemokine receptor binding(GO:0031731) |
| 1.1 | 4.4 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
| 1.1 | 6.5 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
| 1.0 | 4.1 | GO:0045569 | TRAIL binding(GO:0045569) |
| 0.7 | 5.3 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
| 0.6 | 2.4 | GO:0004668 | protein-arginine deiminase activity(GO:0004668) |
| 0.5 | 2.6 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.5 | 1.4 | GO:0035375 | zymogen binding(GO:0035375) |
| 0.5 | 2.7 | GO:0070996 | type 1 melanocortin receptor binding(GO:0070996) |
| 0.4 | 3.1 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
| 0.4 | 1.7 | GO:0004773 | steryl-sulfatase activity(GO:0004773) |
| 0.4 | 7.8 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
| 0.4 | 3.4 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.4 | 1.2 | GO:0061505 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 0.4 | 1.1 | GO:1904455 | ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455) |
| 0.4 | 2.2 | GO:1990254 | keratin filament binding(GO:1990254) |
| 0.4 | 1.4 | GO:0050253 | retinyl-palmitate esterase activity(GO:0050253) |
| 0.3 | 2.7 | GO:0046923 | ER retention sequence binding(GO:0046923) |
| 0.3 | 1.1 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
| 0.3 | 4.0 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.3 | 1.6 | GO:0004656 | procollagen-proline 4-dioxygenase activity(GO:0004656) |
| 0.2 | 5.7 | GO:0016918 | retinal binding(GO:0016918) |
| 0.2 | 2.1 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.2 | 1.6 | GO:0035473 | lipase binding(GO:0035473) |
| 0.2 | 0.2 | GO:0031735 | CCR10 chemokine receptor binding(GO:0031735) |
| 0.2 | 3.1 | GO:0039706 | co-receptor binding(GO:0039706) |
| 0.2 | 1.1 | GO:0031726 | CCR1 chemokine receptor binding(GO:0031726) |
| 0.2 | 3.0 | GO:0043138 | 3'-5' DNA helicase activity(GO:0043138) |
| 0.2 | 1.8 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.2 | 0.8 | GO:0033300 | dehydroascorbic acid transporter activity(GO:0033300) |
| 0.2 | 1.8 | GO:0060002 | plus-end directed microfilament motor activity(GO:0060002) |
| 0.2 | 1.3 | GO:0004797 | thymidine kinase activity(GO:0004797) |
| 0.2 | 2.8 | GO:0001730 | 2'-5'-oligoadenylate synthetase activity(GO:0001730) |
| 0.2 | 0.7 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) corticotropin-releasing hormone receptor 2 binding(GO:0051431) |
| 0.2 | 0.5 | GO:0035605 | peptidyl-cysteine S-nitrosylase activity(GO:0035605) |
| 0.2 | 2.1 | GO:0033612 | receptor serine/threonine kinase binding(GO:0033612) |
| 0.2 | 2.1 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.2 | 5.7 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.1 | 1.0 | GO:0004771 | sterol esterase activity(GO:0004771) |
| 0.1 | 0.7 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 0.1 | 0.4 | GO:0008903 | hydroxypyruvate isomerase activity(GO:0008903) |
| 0.1 | 1.4 | GO:0032190 | acrosin binding(GO:0032190) |
| 0.1 | 1.0 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 0.1 | 2.3 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.1 | 2.8 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.1 | 2.8 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.1 | 2.2 | GO:0005132 | type I interferon receptor binding(GO:0005132) |
| 0.1 | 4.5 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.1 | 0.7 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 0.1 | 0.5 | GO:0061769 | ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769) |
| 0.1 | 1.1 | GO:0019960 | C-X3-C chemokine binding(GO:0019960) |
| 0.1 | 2.4 | GO:0005537 | mannose binding(GO:0005537) |
| 0.1 | 17.5 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.1 | 0.7 | GO:0016416 | O-palmitoyltransferase activity(GO:0016416) |
| 0.1 | 1.3 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
| 0.1 | 0.5 | GO:0042015 | interleukin-20 binding(GO:0042015) |
| 0.1 | 0.5 | GO:0070653 | high-density lipoprotein particle receptor binding(GO:0070653) |
| 0.1 | 1.9 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.1 | 0.6 | GO:1990446 | U1 snRNP binding(GO:1990446) |
| 0.1 | 0.8 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.1 | 0.9 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
| 0.1 | 0.5 | GO:0031728 | CCR3 chemokine receptor binding(GO:0031728) |
| 0.1 | 0.8 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
| 0.1 | 0.9 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.1 | 0.3 | GO:0016639 | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639) |
| 0.1 | 0.7 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 0.1 | 1.0 | GO:0008020 | G-protein coupled photoreceptor activity(GO:0008020) |
| 0.1 | 1.8 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.1 | 0.9 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.1 | 3.7 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.1 | 0.2 | GO:0033265 | choline binding(GO:0033265) |
| 0.1 | 0.2 | GO:0004651 | polynucleotide 5'-phosphatase activity(GO:0004651) |
| 0.1 | 0.4 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
| 0.1 | 0.6 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.1 | 0.8 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.1 | 0.2 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 0.1 | 0.3 | GO:0031716 | calcitonin receptor binding(GO:0031716) |
| 0.1 | 3.7 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.1 | 0.6 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.1 | 0.3 | GO:0003875 | ADP-ribosylarginine hydrolase activity(GO:0003875) |
| 0.1 | 0.4 | GO:0003960 | NADPH:quinone reductase activity(GO:0003960) |
| 0.1 | 1.0 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.1 | 0.4 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) |
| 0.1 | 2.9 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.1 | 0.7 | GO:0046870 | cadmium ion binding(GO:0046870) |
| 0.1 | 0.4 | GO:0086083 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083) |
| 0.1 | 0.8 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
| 0.1 | 0.3 | GO:0060228 | phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228) |
| 0.1 | 0.3 | GO:0004748 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 0.1 | 7.5 | GO:0005179 | hormone activity(GO:0005179) |
| 0.1 | 1.4 | GO:0031432 | titin binding(GO:0031432) |
| 0.1 | 0.2 | GO:0008426 | protein kinase C inhibitor activity(GO:0008426) |
| 0.1 | 0.8 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.0 | 1.3 | GO:0001871 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
| 0.0 | 1.2 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 0.0 | 1.3 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.0 | 1.1 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.0 | 1.0 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.0 | 2.9 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.0 | 1.1 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 0.7 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.0 | 0.3 | GO:0015562 | efflux transmembrane transporter activity(GO:0015562) |
| 0.0 | 0.3 | GO:0016715 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) |
| 0.0 | 0.7 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.0 | 0.3 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.0 | 1.7 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.0 | 0.7 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.0 | 1.0 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.0 | 0.3 | GO:0036435 | K48-linked polyubiquitin binding(GO:0036435) |
| 0.0 | 0.1 | GO:0061609 | fructose-1-phosphate aldolase activity(GO:0061609) |
| 0.0 | 0.1 | GO:0032450 | maltose alpha-glucosidase activity(GO:0032450) |
| 0.0 | 0.4 | GO:0008312 | 7S RNA binding(GO:0008312) |
| 0.0 | 7.7 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.0 | 2.4 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.0 | 0.6 | GO:0031404 | chloride ion binding(GO:0031404) |
| 0.0 | 0.8 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.0 | 0.7 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.0 | 0.3 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.0 | 0.3 | GO:0004957 | prostaglandin E receptor activity(GO:0004957) |
| 0.0 | 2.6 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 2.3 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.0 | 0.6 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
| 0.0 | 0.6 | GO:0046965 | retinoid X receptor binding(GO:0046965) |
| 0.0 | 0.8 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.0 | 2.7 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.0 | 0.4 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 0.0 | 3.1 | GO:0002020 | protease binding(GO:0002020) |
| 0.0 | 0.6 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.0 | 0.5 | GO:0001608 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.0 | 1.5 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.0 | 0.7 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.0 | 0.5 | GO:0022840 | leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842) |
| 0.0 | 5.0 | GO:0030674 | protein binding, bridging(GO:0030674) |
| 0.0 | 0.7 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 0.4 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 0.0 | 0.2 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 0.0 | 0.8 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 0.0 | 0.5 | GO:0005313 | L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172) |
| 0.0 | 0.9 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.0 | 0.4 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.0 | 0.3 | GO:0043548 | phosphatidylinositol 3-kinase binding(GO:0043548) |
| 0.0 | 3.2 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.8 | GO:0004177 | aminopeptidase activity(GO:0004177) |
| 0.0 | 0.1 | GO:0046790 | virion binding(GO:0046790) |
| 0.0 | 0.7 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.0 | 0.1 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 0.0 | 0.5 | GO:0016854 | racemase and epimerase activity(GO:0016854) |
| 0.0 | 0.8 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.0 | 0.4 | GO:0016303 | 1-phosphatidylinositol-3-kinase activity(GO:0016303) |
| 0.0 | 0.1 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.0 | 0.2 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.0 | 0.4 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
| 0.0 | 0.1 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 0.0 | 1.6 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 0.0 | 0.5 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.0 | 0.7 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.0 | 4.0 | GO:0008017 | microtubule binding(GO:0008017) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.9 | ST DIFFERENTIATION PATHWAY IN PC12 CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
| 0.1 | 5.2 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.1 | 2.9 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.1 | 4.2 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.1 | 6.2 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.1 | 2.5 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.1 | 7.0 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.1 | 4.4 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.1 | 4.2 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.1 | 1.0 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.1 | 7.0 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.1 | 1.8 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.1 | 4.1 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 0.1 | 2.0 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.1 | 0.7 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.1 | 3.3 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.1 | 18.9 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 3.2 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 0.1 | 3.0 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 2.1 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.0 | 1.7 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 3.4 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 1.8 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.0 | 1.4 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.0 | 2.3 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 0.7 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 1.5 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 0.0 | 0.4 | ST TYPE I INTERFERON PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
| 0.0 | 11.5 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 1.4 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 1.5 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.0 | 0.7 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.0 | 0.8 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.0 | 0.5 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.0 | 0.3 | ST ADRENERGIC | Adrenergic Pathway |
| 0.0 | 0.3 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 0.6 | PID AP1 PATHWAY | AP-1 transcription factor network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 6.1 | REACTOME PEPTIDE HORMONE BIOSYNTHESIS | Genes involved in Peptide hormone biosynthesis |
| 0.2 | 11.6 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.2 | 3.0 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.1 | 4.4 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
| 0.1 | 6.2 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.1 | 3.6 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.1 | 1.7 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 0.1 | 1.9 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.1 | 4.2 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.1 | 2.2 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.1 | 2.9 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.1 | 2.2 | REACTOME REGULATION OF IFNA SIGNALING | Genes involved in Regulation of IFNA signaling |
| 0.1 | 2.1 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.1 | 0.9 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.1 | 1.0 | REACTOME OPSINS | Genes involved in Opsins |
| 0.1 | 0.8 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.1 | 0.4 | REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL | Genes involved in NF-kB is activated and signals survival |
| 0.1 | 2.2 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.1 | 1.4 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.1 | 8.4 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.1 | 6.8 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
| 0.1 | 1.2 | REACTOME SIGNALING BY FGFR3 MUTANTS | Genes involved in Signaling by FGFR3 mutants |
| 0.1 | 1.3 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.1 | 0.3 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.1 | 0.9 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.1 | 1.4 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.0 | 0.3 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 0.0 | 1.9 | REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
| 0.0 | 0.7 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.0 | 1.2 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.0 | 0.4 | REACTOME DEFENSINS | Genes involved in Defensins |
| 0.0 | 0.6 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.0 | 2.3 | REACTOME TRAFFICKING OF AMPA RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.0 | 0.8 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.0 | 1.3 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.0 | 0.3 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.0 | 1.5 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 3.7 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 0.3 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 0.0 | 1.6 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.0 | 5.1 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 0.0 | 1.0 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
| 0.0 | 1.5 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.0 | 1.2 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 0.2 | REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
| 0.0 | 0.3 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.0 | 1.1 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 0.7 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 0.7 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.0 | 2.1 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 0.2 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.0 | 0.5 | REACTOME AMINE COMPOUND SLC TRANSPORTERS | Genes involved in Amine compound SLC transporters |
| 0.0 | 0.7 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.0 | 0.4 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 1.1 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 0.3 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.0 | 0.3 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 0.0 | 1.5 | REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
| 0.0 | 1.0 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.0 | 1.1 | REACTOME G ALPHA S SIGNALLING EVENTS | Genes involved in G alpha (s) signalling events |
| 0.0 | 1.4 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |