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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for TBX2

Z-value: 0.52

Motif logo

Transcription factors associated with TBX2

Gene Symbol Gene ID Gene Info
ENSG00000121068.14 TBX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX2hg38_v1_chr17_+_61399835_61399851-0.048.4e-01Click!

Activity profile of TBX2 motif

Sorted Z-values of TBX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_-_76626127 1.70 ENST00000454397.1
POM121 and ZP3 fusion
chr1_-_75611109 1.01 ENST00000370859.7
solute carrier family 44 member 5
chr19_-_17405554 0.72 ENST00000252593.7
bone marrow stromal cell antigen 2
chr11_+_73647549 0.56 ENST00000227214.10
ENST00000398494.8
ENST00000543085.5
pleckstrin homology domain containing B1
chr7_+_105963253 0.50 ENST00000478080.5
ENST00000317716.14
cadherin related family member 3
chr17_+_41712325 0.48 ENST00000329402.4
gastrin
chr11_+_6239068 0.48 ENST00000379936.3
cyclic nucleotide gated channel subunit alpha 4
chr1_+_37556913 0.47 ENST00000296218.8
ENST00000652629.1
dynein axonemal light intermediate chain 1
chrX_+_16786421 0.47 ENST00000398155.4
ENST00000380122.10
taxilin gamma
chr14_+_75069632 0.44 ENST00000439583.2
ENST00000554763.2
ENST00000524913.3
ENST00000525046.2
ENST00000674086.1
ENST00000526130.2
ENST00000674094.1
ENST00000532198.2
zinc finger C2HC-type containing 1C
chr12_-_106987131 0.41 ENST00000240050.9
ENST00000392830.6
mitochondrial transcription termination factor 2
chr10_+_93073873 0.40 ENST00000224356.5
cytochrome P450 family 26 subfamily A member 1
chr15_+_41332862 0.40 ENST00000450592.6
ENST00000414849.6
ENST00000559596.6
ENST00000560747.5
ENST00000560177.5
nucleolar and spindle associated protein 1
chr2_+_178320228 0.40 ENST00000315022.2
oxysterol binding protein like 6
chr2_+_227871618 0.39 ENST00000309931.3
ENST00000440997.1
dynein assembly factor with WD repeats 1
chr10_+_52314272 0.36 ENST00000373970.4
dickkopf WNT signaling pathway inhibitor 1
chr20_-_51802433 0.36 ENST00000395997.3
spalt like transcription factor 4
chr14_+_94612383 0.36 ENST00000393080.8
ENST00000555820.1
ENST00000393078.5
ENST00000467132.5
serpin family A member 3
chr5_-_103562775 0.36 ENST00000230792.7
ENST00000507423.1
nudix hydrolase 12
chr2_+_53767772 0.36 ENST00000295304.5
ChaC glutathione specific gamma-glutamylcyclotransferase 2
chr12_+_56266934 0.36 ENST00000308197.10
coenzyme Q10A
chr13_+_23570370 0.35 ENST00000403372.6
ENST00000248484.9
TNF receptor superfamily member 19
chr17_+_37489882 0.35 ENST00000617516.5
dual specificity phosphatase 14
chr19_-_50025936 0.35 ENST00000596445.5
ENST00000599538.5
VRK serine/threonine kinase 3
chr14_-_55191534 0.34 ENST00000395425.6
ENST00000247191.7
DLG associated protein 5
chr3_+_101779425 0.34 ENST00000491511.6
neurexophilin and PC-esterase domain family member 3
chr12_+_56267249 0.34 ENST00000433805.6
coenzyme Q10A
chrX_+_30235894 0.34 ENST00000620842.1
MAGE family member B3
chr2_-_135047432 0.34 ENST00000392915.7
ENST00000637841.1
ENST00000414343.1
mitogen-activated protein kinase kinase kinase 19
chr7_-_138701352 0.34 ENST00000421622.5
ENST00000674285.1
SVOP like
chr2_+_240625237 0.33 ENST00000407714.1
G protein-coupled receptor 35
chr7_-_99929620 0.33 ENST00000312891.3
gap junction protein gamma 3
chr12_+_75481204 0.33 ENST00000550491.1
GLI pathogenesis related 1
chr11_-_16408853 0.33 ENST00000528252.5
SRY-box transcription factor 6
chr20_-_51802509 0.33 ENST00000371539.7
ENST00000217086.9
spalt like transcription factor 4
chr15_-_51738095 0.33 ENST00000560491.2
LysM domain containing 2
chr17_+_7687416 0.32 ENST00000457584.6
WD repeat containing antisense to TP53
chr1_-_47314089 0.32 ENST00000360380.7
ENST00000371877.8
ENST00000447475.7
STIL centriolar assembly protein
chr2_-_168913277 0.32 ENST00000451987.5
SPC25 component of NDC80 kinetochore complex
chr19_-_51372640 0.32 ENST00000600427.5
ENST00000221978.10
natural killer cell granule protein 7
chr1_+_101237009 0.32 ENST00000305352.7
sphingosine-1-phosphate receptor 1
chr6_-_24935942 0.32 ENST00000645100.1
ENST00000643898.2
ENST00000613507.4
RHO family interacting cell polarization regulator 2
chr9_+_214843 0.31 ENST00000432829.7
dedicator of cytokinesis 8
chr22_-_38302990 0.30 ENST00000612795.2
ENST00000451964.5
casein kinase 1 epsilon
chr11_-_615570 0.30 ENST00000649187.1
ENST00000647801.1
ENST00000397566.5
ENST00000397570.5
interferon regulatory factor 7
chr11_-_28108109 0.30 ENST00000263181.7
kinesin family member 18A
chr1_+_76074698 0.30 ENST00000328299.4
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr20_+_59628609 0.29 ENST00000541461.5
phosphatase and actin regulator 3
chr6_-_84227596 0.29 ENST00000257766.8
centrosomal protein 162
chr12_-_106987068 0.29 ENST00000548101.1
ENST00000550496.1
ENST00000552029.1
mitochondrial transcription termination factor 2
chr6_-_84227634 0.29 ENST00000617909.1
ENST00000403245.8
centrosomal protein 162
chr17_-_61928005 0.28 ENST00000444766.7
integrator complex subunit 2
chr17_-_61927968 0.28 ENST00000646954.1
ENST00000251334.7
ENST00000647009.1
integrator complex subunit 2
chr1_+_20589044 0.28 ENST00000375071.4
cytidine deaminase
chr6_-_32530268 0.27 ENST00000374975.4
major histocompatibility complex, class II, DR beta 5
chr11_+_108665045 0.27 ENST00000322536.8
DEAD-box helicase 10
chr1_-_224330121 0.27 ENST00000469968.5
ENST00000436927.5
ENST00000469075.5
ENST00000488718.5
ENST00000340871.8
ENST00000492281.5
ENST00000391875.6
ENST00000281701.11
ENST00000461546.2
ENST00000482491.5
nuclear VCP like
chr14_+_21057822 0.26 ENST00000308227.2
ribonuclease A family member 8
chr2_+_188291854 0.25 ENST00000409830.6
GULP PTB domain containing engulfment adaptor 1
chr5_-_71067601 0.25 ENST00000274400.9
ENST00000521602.2
ENST00000330280.11
ENST00000517900.5
general transcription factor IIH subunit 2
chr2_-_199457931 0.25 ENST00000417098.6
SATB homeobox 2
chr2_-_119366682 0.25 ENST00000409877.5
ENST00000409523.1
ENST00000409466.6
chromosome 2 open reading frame 76
chr10_-_70132801 0.25 ENST00000307864.3
ENST00000613322.4
apoptosis inducing factor mitochondria associated 2
chr10_-_73358853 0.25 ENST00000355577.8
ENST00000310715.7
cilia and flagella associated protein 70
chr10_+_112376193 0.24 ENST00000433418.6
ENST00000356116.6
ENST00000354273.5
acyl-CoA synthetase long chain family member 5
chrX_+_136205982 0.24 ENST00000628568.1
four and a half LIM domains 1
chr2_-_119366807 0.24 ENST00000334816.12
chromosome 2 open reading frame 76
chr15_+_41838839 0.24 ENST00000458483.4
phospholipase A2 group IVB
chr17_-_7329266 0.23 ENST00000571887.5
ENST00000315614.11
ENST00000399464.7
ENST00000570460.5
neuralized E3 ubiquitin protein ligase 4
chr4_-_74038681 0.23 ENST00000296026.4
C-X-C motif chemokine ligand 3
chr12_+_65279092 0.23 ENST00000646299.1
methionine sulfoxide reductase B3
chr3_-_184017863 0.23 ENST00000427120.6
ENST00000334444.11
ENST00000392579.6
ENST00000382494.6
ENST00000265586.10
ENST00000446941.2
ATP binding cassette subfamily C member 5
chr7_+_27242700 0.23 ENST00000222761.7
even-skipped homeobox 1
chr4_-_167234266 0.22 ENST00000511269.5
ENST00000506697.5
ENST00000512042.1
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr4_-_167234552 0.22 ENST00000512648.5
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr12_-_120581361 0.22 ENST00000341039.6
ENST00000357500.5
POP5 homolog, ribonuclease P/MRP subunit
chr1_-_200620729 0.22 ENST00000367350.5
kinesin family member 14
chr22_+_41800662 0.22 ENST00000402061.7
ENST00000255784.6
coiled-coil domain containing 134
chr8_-_123416327 0.21 ENST00000521903.5
ATPase family AAA domain containing 2
chr22_-_50326935 0.21 ENST00000413817.8
DENN domain containing 6B
chr11_-_615921 0.21 ENST00000348655.11
ENST00000525445.6
ENST00000330243.9
interferon regulatory factor 7
chr5_-_9630351 0.21 ENST00000382492.4
taste 2 receptor member 1
chr16_-_2329687 0.21 ENST00000567910.1
ATP binding cassette subfamily A member 3
chr1_-_26306576 0.21 ENST00000421827.2
ENST00000374215.5
ENST00000374223.5
ENST00000357089.8
ENST00000314675.11
ENST00000423664.5
ENST00000374221.7
UBX domain protein 11
chr12_+_65278643 0.21 ENST00000355192.8
ENST00000308259.10
ENST00000540804.5
ENST00000535664.5
ENST00000541189.5
methionine sulfoxide reductase B3
chr8_+_31639222 0.20 ENST00000519301.6
ENST00000652698.1
neuregulin 1
chr3_-_39154558 0.20 ENST00000514182.1
cysteine and serine rich nuclear protein 1
chr12_+_65279445 0.20 ENST00000642404.1
methionine sulfoxide reductase B3
chr6_+_159800249 0.20 ENST00000610273.5
ENST00000392167.4
PARN like, ribonuclease domain containing 1
chr1_-_79006680 0.19 ENST00000370742.4
ENST00000656841.1
adhesion G protein-coupled receptor L4
chr19_+_3762705 0.19 ENST00000589174.1
mitochondrial ribosomal protein L54
chr18_+_58196736 0.19 ENST00000675221.1
NEDD4 like E3 ubiquitin protein ligase
chr12_-_48924919 0.19 ENST00000444214.6
FKBP prolyl isomerase 11
chr16_-_30429207 0.19 ENST00000568434.1
dCTP pyrophosphatase 1
chr1_-_79006773 0.19 ENST00000671209.1
adhesion G protein-coupled receptor L4
chr18_-_50266481 0.19 ENST00000398545.5
cilia and flagella associated protein 53
chr22_-_50562903 0.19 ENST00000406915.4
synaptonemal complex central element protein 3
chr4_-_167234426 0.19 ENST00000541354.5
ENST00000509854.5
ENST00000512681.5
ENST00000357545.9
ENST00000510741.5
ENST00000510403.5
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr3_+_102099244 0.18 ENST00000491959.5
zona pellucida like domain containing 1
chr10_-_110918934 0.18 ENST00000605742.5
BBSome interacting protein 1
chr19_+_35745613 0.18 ENST00000222266.2
ENST00000587708.7
presenilin enhancer, gamma-secretase subunit
chr12_-_89708816 0.18 ENST00000428670.8
ATPase plasma membrane Ca2+ transporting 1
chr9_+_26956384 0.18 ENST00000518614.5
ENST00000380062.10
intraflagellar transport 74
chr1_+_209704836 0.18 ENST00000367027.5
hydroxysteroid 11-beta dehydrogenase 1
chr4_-_167234579 0.18 ENST00000502330.5
ENST00000357154.7
ENST00000421836.6
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr5_+_83471925 0.18 ENST00000502527.2
versican
chr19_+_35745590 0.17 ENST00000591949.1
presenilin enhancer, gamma-secretase subunit
chr3_-_151278535 0.17 ENST00000309170.8
purinergic receptor P2Y14
chr3_+_148730100 0.17 ENST00000474935.5
ENST00000475347.5
ENST00000461609.1
angiotensin II receptor type 1
chr19_-_41436439 0.17 ENST00000594660.5
distal membrane arm assembly complex 2
chr19_-_10315987 0.17 ENST00000393708.3
ENST00000494368.5
ferredoxin 2
chr21_+_39452077 0.16 ENST00000452550.5
SH3 domain binding glutamate rich protein
chr5_-_65563117 0.16 ENST00000508421.5
ENST00000510693.5
ENST00000514814.5
ENST00000396679.6
ENST00000515497.5
centromere protein K
chr17_-_76551174 0.16 ENST00000589145.1
cytoglobin
chrX_-_19670983 0.16 ENST00000379716.5
SH3 domain containing kinase binding protein 1
chr3_+_32685128 0.16 ENST00000331889.10
ENST00000328834.9
CCR4-NOT transcription complex subunit 10
chr17_-_15263162 0.16 ENST00000674673.1
ENST00000675950.1
peripheral myelin protein 22
chr4_-_103076688 0.16 ENST00000394785.9
solute carrier family 9 member B2
chr10_+_112375196 0.16 ENST00000393081.6
acyl-CoA synthetase long chain family member 5
chr2_-_234497035 0.15 ENST00000390645.2
ENST00000339728.6
ADP ribosylation factor like GTPase 4C
chr19_-_10102659 0.15 ENST00000592641.5
ENST00000253109.5
angiopoietin like 6
chrX_+_96883908 0.15 ENST00000373040.4
replication protein A4
chr3_-_52409783 0.15 ENST00000470173.1
ENST00000296288.9
ENST00000460680.6
BRCA1 associated protein 1
chr1_+_28259473 0.15 ENST00000253063.4
sestrin 2
chr10_-_110919146 0.15 ENST00000652396.1
ENST00000423273.5
ENST00000436562.1
ENST00000651952.1
ENST00000448814.7
ENST00000652400.1
ENST00000447005.5
ENST00000454061.5
BBSome interacting protein 1
chr7_-_18027839 0.15 ENST00000506618.5
phosphoribosyl pyrophosphate synthetase 1 like 1
chr19_-_40750302 0.15 ENST00000598485.6
ENST00000378313.7
ENST00000470681.5
chromosome 19 open reading frame 54
chr12_-_86838867 0.14 ENST00000621808.4
MGAT4 family member C
chr4_-_47914569 0.14 ENST00000507489.2
nuclear transcription factor, X-box binding like 1
chr19_-_10315737 0.14 ENST00000492239.5
ferredoxin 2
chr8_+_31639291 0.14 ENST00000651149.1
ENST00000650866.1
neuregulin 1
chr5_+_35856883 0.14 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
interleukin 7 receptor
chr2_-_175005357 0.14 ENST00000409156.7
ENST00000444573.2
ENST00000409900.9
chimerin 1
chr16_+_14945885 0.14 ENST00000537062.1
nuclear pore complex interacting protein family member A1
chr8_+_737595 0.14 ENST00000637795.2
DLG associated protein 2
chr13_+_108596152 0.14 ENST00000356711.7
ENST00000251041.10
myosin XVI
chr19_-_54360949 0.14 ENST00000622064.1
leukocyte associated immunoglobulin like receptor 1
chr2_+_177392734 0.14 ENST00000680770.1
ENST00000637633.2
ENST00000679459.1
ENST00000409888.1
ENST00000264167.11
ENST00000642466.2
alkylglycerone phosphate synthase
chr8_+_143684448 0.14 ENST00000534303.5
ENST00000529833.5
ENST00000530574.5
ENST00000358656.9
ENST00000442058.6
ENST00000526970.5
ENST00000532158.5
zinc finger protein 707
chr10_+_125719689 0.14 ENST00000337623.7
ENST00000356792.9
erythroid differentiation regulatory factor 1
chr1_-_46132616 0.14 ENST00000423209.5
ENST00000262741.10
phosphoinositide-3-kinase regulatory subunit 3
chr11_-_6683282 0.14 ENST00000532203.1
ENST00000288937.7
mitochondrial ribosomal protein L17
chr6_-_33711717 0.14 ENST00000374214.3
ubiquinol-cytochrome c reductase complex assembly factor 2
chr20_-_45887617 0.14 ENST00000372519.4
spermatogenesis associated 25
chr17_-_56833889 0.14 ENST00000397861.7
chromosome 17 open reading frame 67
chr8_+_143684499 0.14 ENST00000526315.5
ENST00000532205.5
zinc finger protein 707
chr11_-_93197932 0.13 ENST00000326402.9
solute carrier family 36 member 4
chr5_+_134525649 0.13 ENST00000282605.8
ENST00000681547.2
ENST00000361895.6
ENST00000402835.5
jade family PHD finger 2
chr20_+_45363114 0.13 ENST00000426004.5
ENST00000243918.10
SYS1 golgi trafficking protein
chr10_-_70602687 0.13 ENST00000638674.1
perforin 1
chr13_+_33818122 0.13 ENST00000380071.8
replication factor C subunit 3
chr1_+_162790702 0.13 ENST00000254521.8
ENST00000367915.1
hydroxysteroid 17-beta dehydrogenase 7
chr12_+_65278919 0.13 ENST00000538045.5
ENST00000642411.1
ENST00000535239.5
ENST00000614640.4
methionine sulfoxide reductase B3
chr7_+_27242796 0.13 ENST00000496902.7
even-skipped homeobox 1
chr12_-_81758641 0.13 ENST00000552948.5
ENST00000548586.5
PTPRF interacting protein alpha 2
chr18_-_55302613 0.13 ENST00000561831.7
transcription factor 4
chr19_-_13102848 0.13 ENST00000264824.5
LYL1 basic helix-loop-helix family member
chr2_-_215138603 0.13 ENST00000272895.12
ATP binding cassette subfamily A member 12
chr19_+_3762665 0.13 ENST00000330133.5
mitochondrial ribosomal protein L54
chr1_-_46132650 0.13 ENST00000372006.5
ENST00000425892.2
ENST00000420542.5
phosphoinositide-3-kinase regulatory subunit 3
chr19_-_35745391 0.13 ENST00000378975.8
ENST00000587886.2
ENST00000412391.6
ENST00000292879.9
U2 small nuclear RNA auxiliary factor 1 like 4
chr3_+_99817849 0.13 ENST00000421999.8
cms1 ribosomal small subunit homolog
chr17_+_50746614 0.12 ENST00000513969.5
ENST00000503728.1
LUC7 like 3 pre-mRNA splicing factor
chr14_-_90816381 0.12 ENST00000328459.11
tetratricopeptide repeat domain 7B
chr7_+_35800932 0.12 ENST00000635172.1
ENST00000399034.7
ENST00000350320.10
ENST00000435235.6
ENST00000672279.1
ENST00000634600.1
ENST00000635047.1
septin 7
chr19_+_52429181 0.12 ENST00000301085.8
zinc finger protein 534
chr16_+_57976435 0.12 ENST00000290871.10
ENST00000441824.4
testis, prostate and placenta expressed
chr12_+_96489569 0.12 ENST00000524981.9
cilia and flagella associated protein 54
chr3_-_48301577 0.12 ENST00000451657.6
NME/NM23 nucleoside diphosphate kinase 6
chr5_-_131797030 0.12 ENST00000615660.4
folliculin interacting protein 1
chr9_-_136746006 0.12 ENST00000476567.1
lipocalin 6
chr3_+_160399630 0.12 ENST00000465903.5
ENST00000485645.5
ENST00000472991.5
ENST00000467468.5
ENST00000469762.5
ENST00000357388.8
ENST00000489573.5
ENST00000462787.5
ENST00000490207.5
ENST00000485867.5
structural maintenance of chromosomes 4
chr13_-_20773927 0.12 ENST00000382758.6
EEF1A lysine methyltransferase 1
chr1_-_111563934 0.11 ENST00000443498.5
transmembrane and immunoglobulin domain containing 3
chr14_-_24442241 0.11 ENST00000555355.5
ENST00000553343.5
ENST00000556523.1
ENST00000556249.1
ENST00000538105.6
ENST00000555225.5
short chain dehydrogenase/reductase family 39U member 1
chr10_+_93496599 0.11 ENST00000371485.8
centrosomal protein 55
chr9_-_100352903 0.11 ENST00000374902.9
testis expressed 10
chr16_-_2268054 0.11 ENST00000561518.5
ENST00000561718.5
ENST00000567147.5
ENST00000562690.5
ENST00000569598.6
RNA binding protein with serine rich domain 1
chr14_-_69152972 0.11 ENST00000389997.10
ENST00000557386.5
ENST00000554681.1
DDB1 and CUL4 associated factor 5
chr19_-_3500625 0.11 ENST00000672935.1
deoxyhypusine hydroxylase
chr6_+_131573219 0.11 ENST00000356962.2
ENST00000368087.8
ENST00000673427.1
ENST00000640973.1
arginase 1
chr5_-_131796921 0.11 ENST00000307968.11
ENST00000307954.12
folliculin interacting protein 1
chr17_-_3063607 0.11 ENST00000575751.1
olfactory receptor family 1 subfamily D member 5
chr2_-_79086847 0.11 ENST00000454188.5
regenerating family member 1 beta
chr13_-_20773907 0.11 ENST00000382754.4
EEF1A lysine methyltransferase 1
chr16_-_2268111 0.11 ENST00000301730.12
ENST00000564822.1
ENST00000320225.10
RNA binding protein with serine rich domain 1
chr12_+_66189178 0.11 ENST00000545837.1
interleukin 1 receptor associated kinase 3
chr3_+_126394890 0.11 ENST00000352312.6
cilia and flagella associated protein 100
chr8_-_27600000 0.11 ENST00000521770.1
clusterin
chr2_-_119366757 0.11 ENST00000414534.1
chromosome 2 open reading frame 76
chr17_-_58328756 0.11 ENST00000268893.10
ENST00000343736.9
TSPO associated protein 1
chr12_+_93572664 0.10 ENST00000551556.2
suppressor of cytokine signaling 2
chr15_+_67254776 0.10 ENST00000335894.9
ENST00000512104.5
IQ motif containing H
chr2_+_135586250 0.10 ENST00000410054.5
ENST00000628915.2
R3H domain containing 1
chr15_+_75724034 0.10 ENST00000332145.3
outer dense fiber of sperm tails 3 like 1
chr19_-_44448435 0.10 ENST00000588655.1
ENST00000592308.1
ENST00000614049.5
ENST00000613197.4
novel transcript
zinc finger protein 229
chr12_+_26052563 0.10 ENST00000537946.5
ENST00000541218.5
ENST00000282884.13
ENST00000545413.1
Ras association domain family member 8
chr1_-_110606009 0.10 ENST00000640774.2
ENST00000638616.2
potassium voltage-gated channel subfamily A member 2
chr11_+_124115404 0.10 ENST00000361352.9
ENST00000449321.5
ENST00000392748.5
ENST00000392744.4
ENST00000456829.7
von Willebrand factor A domain containing 5A
chr12_-_89630552 0.10 ENST00000393164.6
ATPase plasma membrane Ca2+ transporting 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0035803 egg coat formation(GO:0035803)
0.2 0.7 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.2 0.7 GO:0006393 termination of mitochondrial transcription(GO:0006393)
0.1 0.4 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.1 0.4 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.1 0.4 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1 0.4 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.3 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 0.3 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.5 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.1 0.4 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.3 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.1 0.8 GO:0030091 protein repair(GO:0030091)
0.1 0.3 GO:2001107 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.1 0.3 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 1.0 GO:0015871 choline transport(GO:0015871)
0.1 0.3 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.3 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.2 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.1 GO:0060032 notochord regression(GO:0060032)
0.0 0.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.3 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.3 GO:0033504 floor plate development(GO:0033504)
0.0 0.2 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.0 0.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.2 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 0.6 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.3 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.2 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.3 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.1 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 0.1 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.1 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.1 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:1905072 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.1 GO:1903937 response to acrylamide(GO:1903937)
0.0 0.1 GO:0002357 defense response to tumor cell(GO:0002357)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476)
0.0 0.3 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.1 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.7 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.2 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:2000562 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0 0.2 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.1 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.4 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.2 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.4 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.1 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.2 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.1 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.0 0.1 GO:0033306 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.4 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.2 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.2 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.3 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.1 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.0 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.1 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.0 0.3 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.1 GO:0015827 tryptophan transport(GO:0015827)
0.0 0.1 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.1 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
0.0 0.3 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.3 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.0 0.3 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.1 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.3 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.4 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.0 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.0 0.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.5 GO:0032094 response to food(GO:0032094)
0.0 0.1 GO:0021633 optic nerve structural organization(GO:0021633)
0.0 0.1 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.1 GO:0042780 tRNA 3'-end processing(GO:0042780)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.3 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.1 0.1 GO:0097545 axonemal outer doublet(GO:0097545)
0.1 0.3 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.6 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.2 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.3 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 0.1 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 1.3 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 GO:0032190 acrosin binding(GO:0032190)
0.1 0.4 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 1.0 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.4 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.7 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.8 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.2 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.4 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.2 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.3 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.1 1.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.2 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.2 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.3 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.2 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.1 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.0 0.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.5 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.4 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.1 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.3 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.0 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.3 GO:0043125 ErbB-2 class receptor binding(GO:0005176) ErbB-3 class receptor binding(GO:0043125)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.2 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.1 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.0 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0048030 disaccharide binding(GO:0048030)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 1.0 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.4 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.4 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER