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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for TBX21_TBR1

Z-value: 0.88

Motif logo

Transcription factors associated with TBX21_TBR1

Gene Symbol Gene ID Gene Info
ENSG00000073861.3 TBX21
ENSG00000136535.15 TBR1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBR1hg38_v1_chr2_+_161416273_161416325-0.105.9e-01Click!
TBX21hg38_v1_chr17_+_47733228_47733242-0.067.5e-01Click!

Activity profile of TBX21_TBR1 motif

Sorted Z-values of TBX21_TBR1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX21_TBR1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_+_95391361 6.03 ENST00000283357.10
family with sequence similarity 81 member B
chr1_+_37556913 4.69 ENST00000296218.8
ENST00000652629.1
dynein axonemal light intermediate chain 1
chr11_+_73647549 4.25 ENST00000227214.10
ENST00000398494.8
ENST00000543085.5
pleckstrin homology domain containing B1
chr5_-_35938572 2.50 ENST00000651391.1
ENST00000397366.5
ENST00000513623.5
ENST00000514524.2
ENST00000397367.6
calcyphosine like
chr3_-_100993409 2.38 ENST00000471714.6
ABI family member 3 binding protein
chr3_-_100993507 2.34 ENST00000284322.10
ABI family member 3 binding protein
chr1_+_46798998 2.23 ENST00000640628.1
ENST00000271153.8
ENST00000371923.9
ENST00000371919.8
ENST00000614163.4
cytochrome P450 family 4 subfamily B member 1
chr19_-_7926106 2.15 ENST00000318978.6
cortexin 1
chr12_+_69348372 2.15 ENST00000261267.7
ENST00000549690.1
ENST00000548839.1
lysozyme
chr14_+_94612383 2.09 ENST00000393080.8
ENST00000555820.1
ENST00000393078.5
ENST00000467132.5
serpin family A member 3
chr6_-_32530268 1.77 ENST00000374975.4
major histocompatibility complex, class II, DR beta 5
chr12_+_130953898 1.64 ENST00000261654.10
adhesion G protein-coupled receptor D1
chr2_+_227871618 1.47 ENST00000309931.3
ENST00000440997.1
dynein assembly factor with WD repeats 1
chr3_-_66500973 1.44 ENST00000383703.3
ENST00000273261.8
leucine rich repeats and immunoglobulin like domains 1
chr16_-_67416420 1.44 ENST00000348579.6
ENST00000565726.3
zinc finger DHHC-type containing 1
chr11_-_114400417 1.36 ENST00000325636.8
ENST00000623205.2
chromosome 11 open reading frame 71
chr5_+_141192330 1.29 ENST00000239446.6
protocadherin beta 10
chr10_+_116545907 1.28 ENST00000369221.2
pancreatic lipase
chr11_+_6239068 1.22 ENST00000379936.3
cyclic nucleotide gated channel subunit alpha 4
chr11_+_61680373 1.22 ENST00000257215.10
diacylglycerol lipase alpha
chr6_+_39792298 1.19 ENST00000633794.1
ENST00000274867.9
dishevelled associated activator of morphogenesis 2
chr22_+_30607145 1.17 ENST00000405742.7
transcobalamin 2
chrX_+_16786421 1.16 ENST00000398155.4
ENST00000380122.10
taxilin gamma
chr14_+_78170336 1.15 ENST00000634499.2
ENST00000335750.7
neurexin 3
chr1_-_46132650 1.15 ENST00000372006.5
ENST00000425892.2
ENST00000420542.5
phosphoinositide-3-kinase regulatory subunit 3
chr19_-_6433754 1.13 ENST00000321510.7
solute carrier family 25 member 41
chr22_+_30607167 1.12 ENST00000215838.8
transcobalamin 2
chr1_-_46132616 1.12 ENST00000423209.5
ENST00000262741.10
phosphoinositide-3-kinase regulatory subunit 3
chr15_+_60004305 1.11 ENST00000396057.6
forkhead box B1
chr17_+_37489882 1.09 ENST00000617516.5
dual specificity phosphatase 14
chr13_-_38990824 1.09 ENST00000379631.9
stomatin like 3
chr17_-_58328756 1.09 ENST00000268893.10
ENST00000343736.9
TSPO associated protein 1
chr13_-_38990856 1.07 ENST00000423210.1
stomatin like 3
chr22_+_30607203 1.05 ENST00000407817.3
transcobalamin 2
chr1_+_145927105 1.01 ENST00000437797.5
ENST00000601726.3
ENST00000599626.5
ENST00000599147.5
ENST00000595494.5
ENST00000595518.5
ENST00000597144.5
ENST00000599469.5
ENST00000598354.5
ENST00000598103.5
ENST00000600340.5
ENST00000630257.2
ENST00000625258.1
LIX1L antisense RNA 1
novel protein, lncRNA-POLR3GL readthrough
chrX_-_72782660 0.97 ENST00000596535.3
family with sequence similarity 236 member B
chr12_-_89630552 0.94 ENST00000393164.6
ATPase plasma membrane Ca2+ transporting 1
chrX_+_72938163 0.94 ENST00000593662.1
ENST00000611003.2
family with sequence similarity 235 member A
chr7_-_120857124 0.93 ENST00000441017.5
ENST00000424710.5
ENST00000433758.5
tetraspanin 12
chr10_+_112375196 0.93 ENST00000393081.6
acyl-CoA synthetase long chain family member 5
chr13_+_24270681 0.91 ENST00000343003.10
ENST00000399949.6
spermatogenesis associated 13
chr1_+_182789765 0.89 ENST00000367555.5
ENST00000367553.6
N-acetylneuraminate pyruvate lyase
chr2_+_218382265 0.88 ENST00000233202.11
solute carrier family 11 member 1
chr9_-_72953047 0.88 ENST00000297785.8
ENST00000376939.5
aldehyde dehydrogenase 1 family member A1
chrX_+_106168297 0.87 ENST00000337685.6
ENST00000357175.6
PWWP domain containing 3B
chr11_+_73950985 0.86 ENST00000339764.6
DnaJ heat shock protein family (Hsp40) member B13
chrX_+_53422856 0.84 ENST00000414955.6
ENST00000375327.6
RIB43A domain with coiled-coils 1
chr16_+_30201057 0.80 ENST00000569485.5
sulfotransferase family 1A member 3
chr15_-_43266857 0.79 ENST00000349114.8
ENST00000220420.10
transglutaminase 5
chr18_+_58196736 0.78 ENST00000675221.1
NEDD4 like E3 ubiquitin protein ligase
chr11_-_33892010 0.78 ENST00000257818.3
LIM domain only 2
chr19_+_35745590 0.78 ENST00000591949.1
presenilin enhancer, gamma-secretase subunit
chr12_-_7695752 0.78 ENST00000329913.4
growth differentiation factor 3
chr10_+_44911316 0.77 ENST00000544540.5
ENST00000389583.5
transmembrane protein 72
chr19_+_35745613 0.76 ENST00000222266.2
ENST00000587708.7
presenilin enhancer, gamma-secretase subunit
chr6_-_46954922 0.75 ENST00000265417.7
adhesion G protein-coupled receptor F5
chr5_+_102754631 0.74 ENST00000510208.2
peptidylglycine alpha-amidating monooxygenase
chr19_-_50025936 0.73 ENST00000596445.5
ENST00000599538.5
VRK serine/threonine kinase 3
chr3_-_52409783 0.72 ENST00000470173.1
ENST00000296288.9
ENST00000460680.6
BRCA1 associated protein 1
chr1_-_75611109 0.72 ENST00000370859.7
solute carrier family 44 member 5
chr16_+_57447470 0.72 ENST00000262507.11
ENST00000564655.5
ENST00000567072.5
ENST00000567933.5
ENST00000563166.1
coenzyme Q9
chr5_-_75511596 0.71 ENST00000643158.1
ENST00000261415.12
ENST00000646713.1
ENST00000643773.1
ENST00000645866.1
ENST00000644072.2
ENST00000643780.2
ENST00000645483.1
ENST00000642556.1
ENST00000646511.1
ceramide transporter 1
chr6_-_31777319 0.71 ENST00000375688.5
von Willebrand factor A domain containing 7
chr15_-_82647336 0.70 ENST00000617522.4
ENST00000684509.1
cytoplasmic polyadenylation element binding protein 1
chr6_-_52840843 0.70 ENST00000370989.6
glutathione S-transferase alpha 5
chr14_+_77116562 0.69 ENST00000557408.5
transmembrane protein 63C
chrX_-_19670983 0.69 ENST00000379716.5
SH3 domain containing kinase binding protein 1
chr19_+_859654 0.68 ENST00000592860.2
ENST00000327726.11
complement factor D
chr5_+_176238365 0.67 ENST00000341199.10
ENST00000430704.6
ENST00000443967.5
ENST00000429602.7
SUMO interacting motifs containing 1
chr11_-_236326 0.67 ENST00000525237.1
ENST00000382743.9
ENST00000532956.5
ENST00000525319.5
ENST00000524564.5
sirtuin 3
chr2_-_175005357 0.66 ENST00000409156.7
ENST00000444573.2
ENST00000409900.9
chimerin 1
chr1_+_15736251 0.65 ENST00000294454.6
solute carrier family 25 member 34
chr11_+_45885625 0.64 ENST00000241014.6
mitogen-activated protein kinase 8 interacting protein 1
chr4_+_25655822 0.63 ENST00000504570.5
ENST00000382051.8
solute carrier family 34 member 2
chr12_-_91182652 0.63 ENST00000552145.5
ENST00000546745.5
decorin
chr5_+_96876480 0.61 ENST00000437043.8
ENST00000379904.8
endoplasmic reticulum aminopeptidase 2
chr7_-_138701352 0.61 ENST00000421622.5
ENST00000674285.1
SVOP like
chr9_+_87497222 0.61 ENST00000358077.9
death associated protein kinase 1
chr1_+_25820146 0.60 ENST00000525713.5
ENST00000374301.7
mitochondrial fission regulator 1 like
chr2_-_206765274 0.60 ENST00000454776.6
ENST00000449792.5
ENST00000374412.8
malate dehydrogenase 1B
chr12_+_64780465 0.60 ENST00000542120.6
TBC1 domain family member 30
chr1_-_40097216 0.60 ENST00000641083.1
ENST00000641471.1
ENST00000642050.2
ENST00000433473.8
ENST00000439754.6
ENST00000527311.7
ENST00000641319.1
ENST00000449045.7
palmitoyl-protein thioesterase 1
chr1_+_25819926 0.60 ENST00000533762.5
ENST00000529116.5
ENST00000474295.5
ENST00000488327.6
ENST00000472643.5
ENST00000374303.7
ENST00000526894.5
ENST00000524618.5
ENST00000374307.9
mitochondrial fission regulator 1 like
chr5_+_98769273 0.59 ENST00000308234.11
repulsive guidance molecule BMP co-receptor b
chr4_+_159267737 0.59 ENST00000264431.8
Rap guanine nucleotide exchange factor 2
chr1_+_78620432 0.58 ENST00000370751.10
ENST00000459784.6
ENST00000680110.1
ENST00000680295.1
interferon induced protein 44 like
chr4_-_69653223 0.58 ENST00000286604.8
ENST00000505512.1
ENST00000514019.1
UDP glucuronosyltransferase family 2 member A1 complex locus
chr6_+_167325071 0.56 ENST00000649884.1
ENST00000239587.10
tubulin tyrosine ligase like 2
chr11_+_64306227 0.55 ENST00000405666.5
ENST00000468670.2
estrogen related receptor alpha
chr1_-_108200849 0.55 ENST00000569674.1
solute carrier family 25 member 24
chr1_-_114581589 0.53 ENST00000369541.4
BCAS2 pre-mRNA processing factor
chr2_-_156332694 0.53 ENST00000424077.1
ENST00000426264.5
ENST00000421709.1
ENST00000339562.9
nuclear receptor subfamily 4 group A member 2
chr3_-_187745460 0.53 ENST00000406870.7
BCL6 transcription repressor
chr20_+_59628609 0.52 ENST00000541461.5
phosphatase and actin regulator 3
chr17_-_7329266 0.52 ENST00000571887.5
ENST00000315614.11
ENST00000399464.7
ENST00000570460.5
neuralized E3 ubiquitin protein ligase 4
chr1_+_78620722 0.51 ENST00000679848.1
interferon induced protein 44 like
chr16_+_53099100 0.51 ENST00000565832.5
chromodomain helicase DNA binding protein 9
chr6_+_131573219 0.51 ENST00000356962.2
ENST00000368087.8
ENST00000673427.1
ENST00000640973.1
arginase 1
chr1_+_147541491 0.50 ENST00000683836.1
ENST00000234739.8
BCL9 transcription coactivator
chr1_-_154859841 0.50 ENST00000361147.8
potassium calcium-activated channel subfamily N member 3
chr9_+_26956384 0.50 ENST00000518614.5
ENST00000380062.10
intraflagellar transport 74
chr11_+_6481473 0.49 ENST00000530751.1
ENST00000254616.11
translocase of inner mitochondrial membrane 10B
chr1_-_26306576 0.48 ENST00000421827.2
ENST00000374215.5
ENST00000374223.5
ENST00000357089.8
ENST00000314675.11
ENST00000423664.5
ENST00000374221.7
UBX domain protein 11
chr12_-_90955172 0.47 ENST00000358859.3
coiled-coil glutamate rich protein 1
chr12_+_12049840 0.47 ENST00000589718.5
BCL2 like 14
chr12_+_12049855 0.47 ENST00000586576.5
ENST00000464885.6
BCL2 like 14
chr12_+_41188301 0.45 ENST00000402685.7
PDZ domain containing ring finger 4
chr22_-_17221841 0.45 ENST00000449907.7
ENST00000441548.1
ENST00000399839.5
adenosine deaminase 2
chr7_+_121328991 0.44 ENST00000222462.3
Wnt family member 16
chr4_+_73869385 0.44 ENST00000395761.4
C-X-C motif chemokine ligand 1
chr19_-_10102659 0.44 ENST00000592641.5
ENST00000253109.5
angiopoietin like 6
chr3_-_61251376 0.43 ENST00000476844.5
ENST00000488467.5
ENST00000492590.6
ENST00000468189.5
fragile histidine triad diadenosine triphosphatase
chr2_+_98087160 0.43 ENST00000477737.6
von Willebrand factor A domain containing 3B
chr16_-_20669855 0.43 ENST00000524149.5
acyl-CoA synthetase medium chain family member 1
chr12_+_66189208 0.42 ENST00000261233.9
interleukin 1 receptor associated kinase 3
chr10_+_123008966 0.41 ENST00000368869.8
ENST00000358776.7
acyl-CoA dehydrogenase short/branched chain
chr12_-_106987068 0.41 ENST00000548101.1
ENST00000550496.1
ENST00000552029.1
mitochondrial transcription termination factor 2
chr12_-_106987131 0.41 ENST00000240050.9
ENST00000392830.6
mitochondrial transcription termination factor 2
chr12_+_66189178 0.41 ENST00000545837.1
interleukin 1 receptor associated kinase 3
chr9_-_76906041 0.41 ENST00000443509.6
ENST00000428286.5
ENST00000376713.3
prune homolog 2 with BCH domain
chr5_-_75511213 0.40 ENST00000644445.1
ENST00000646302.1
ENST00000644912.1
ENST00000642809.1
ENST00000644377.1
ceramide transporter 1
chr22_-_23767876 0.40 ENST00000520222.1
ENST00000401675.7
ENST00000484558.3
coiled-coil-helix-coiled-coil-helix domain containing 10
chrX_+_72912615 0.39 ENST00000636532.1
ENST00000636267.1
family with sequence similarity 236 member C
chr20_-_32657362 0.39 ENST00000360785.6
chromosome 20 open reading frame 203
chr5_+_150660841 0.39 ENST00000297130.4
myozenin 3
chr18_+_58045683 0.38 ENST00000592846.5
ENST00000675801.1
NEDD4 like E3 ubiquitin protein ligase
chr7_-_100428657 0.38 ENST00000360951.8
ENST00000398027.6
ENST00000684423.1
ENST00000472716.1
zinc finger CW-type and PWWP domain containing 1
chr20_+_45881218 0.38 ENST00000372523.1
zinc finger SWIM-type containing 1
chr3_+_111292719 0.38 ENST00000460744.1
CD96 molecule
chr7_-_92246045 0.37 ENST00000394507.5
ENST00000458177.6
ENST00000340022.6
ENST00000444960.5
KRIT1 ankyrin repeat containing
chr11_+_129815841 0.37 ENST00000281441.8
transmembrane protein 45B
chr7_-_76626127 0.37 ENST00000454397.1
POM121 and ZP3 fusion
chr5_-_131796921 0.36 ENST00000307968.11
ENST00000307954.12
folliculin interacting protein 1
chr5_-_131797030 0.36 ENST00000615660.4
folliculin interacting protein 1
chr12_+_8082260 0.36 ENST00000638237.1
ENST00000339754.11
ENST00000639811.1
ENST00000639167.1
ENST00000541948.2
NECAP endocytosis associated 1
chr22_-_40819324 0.36 ENST00000435456.7
ENST00000434185.1
ENST00000544408.5
solute carrier family 25 member 17
chr6_-_13487593 0.36 ENST00000379287.4
ENST00000603223.1
glucose-fructose oxidoreductase domain containing 1
chr1_-_1074303 0.35 ENST00000453464.3
ring finger protein 223
chr19_+_50025989 0.35 ENST00000445728.7
ENST00000270617.8
ENST00000601364.5
zinc finger protein 473
chr5_+_140827950 0.35 ENST00000378126.4
ENST00000529310.6
ENST00000527624.1
protocadherin alpha 6
chr1_-_34929574 0.35 ENST00000373347.6
DLG associated protein 3
chrX_-_53422644 0.34 ENST00000322213.9
ENST00000375340.10
ENST00000674590.1
structural maintenance of chromosomes 1A
chr12_+_56080155 0.34 ENST00000267101.8
erb-b2 receptor tyrosine kinase 3
chr19_-_51372640 0.34 ENST00000600427.5
ENST00000221978.10
natural killer cell granule protein 7
chr22_+_18110305 0.34 ENST00000680175.1
ENST00000426208.5
tubulin alpha 8
chr11_-_44950867 0.34 ENST00000528290.5
ENST00000525680.6
ENST00000530035.5
ENST00000527685.5
tumor protein p53 inducible protein 11
chr15_-_51738095 0.34 ENST00000560491.2
LysM domain containing 2
chr7_-_88220025 0.34 ENST00000419179.5
ENST00000265729.7
sorcin
chr9_-_114505437 0.33 ENST00000374057.3
ENST00000362057.4
ENST00000673697.1
whirlin
chr15_-_82647503 0.33 ENST00000567678.1
ENST00000620182.4
cytoplasmic polyadenylation element binding protein 1
chr2_-_218166951 0.33 ENST00000295683.3
C-X-C motif chemokine receptor 1
chr19_+_50025714 0.32 ENST00000598809.5
ENST00000595661.5
ENST00000391821.6
zinc finger protein 473
chr4_-_74038681 0.32 ENST00000296026.4
C-X-C motif chemokine ligand 3
chr9_-_133336169 0.32 ENST00000372022.6
surfeit 6
chr12_+_113185702 0.32 ENST00000548278.2
RBPJ interacting and tubulin associated 1
chr16_-_67931859 0.32 ENST00000574481.6
ENST00000571044.5
ENST00000571605.1
chymotrypsin like
chr7_+_74209386 0.31 ENST00000344995.9
linker for activation of T cells family member 2
chr19_-_35745391 0.31 ENST00000378975.8
ENST00000587886.2
ENST00000412391.6
ENST00000292879.9
U2 small nuclear RNA auxiliary factor 1 like 4
chr12_-_14951106 0.31 ENST00000541644.5
ENST00000545895.5
Rho GDP dissociation inhibitor beta
chr12_-_52703522 0.31 ENST00000341809.8
keratin 77
chr5_+_150661243 0.31 ENST00000517768.6
myozenin 3
chr6_+_29395631 0.31 ENST00000642051.1
olfactory receptor family 12 subfamily D member 2
chr12_-_91182784 0.30 ENST00000547568.6
ENST00000052754.10
ENST00000552962.5
decorin
chr5_+_75511756 0.30 ENST00000241436.8
DNA polymerase kappa
chrX_+_18425579 0.30 ENST00000379996.7
cyclin dependent kinase like 5
chr8_-_81483226 0.30 ENST00000256104.5
fatty acid binding protein 4
chr17_+_6756035 0.30 ENST00000361842.8
ENST00000574907.5
XIAP associated factor 1
chr10_-_118595637 0.30 ENST00000239032.4
prolactin releasing hormone receptor
chr11_-_16356538 0.30 ENST00000683767.1
SRY-box transcription factor 6
chr10_-_63269057 0.30 ENST00000542921.5
jumonji domain containing 1C
chr2_-_199457931 0.30 ENST00000417098.6
SATB homeobox 2
chr12_+_31959406 0.29 ENST00000540924.5
ENST00000312561.9
retroelement silencing factor 1
chr12_+_14419136 0.29 ENST00000545769.1
ENST00000428217.6
ENST00000396279.2
ENST00000542514.5
ENST00000536279.1
activating transcription factor 7 interacting protein
chr5_-_131796965 0.29 ENST00000514667.1
ENST00000511848.1
ENST00000510461.6
novel protein
folliculin interacting protein 1
chr4_+_139665768 0.29 ENST00000616265.4
ENST00000265498.6
ENST00000506797.5
microsomal glutathione S-transferase 2
chr18_+_58045642 0.29 ENST00000676223.1
ENST00000675147.1
NEDD4 like E3 ubiquitin protein ligase
chrX_-_129654946 0.29 ENST00000429967.3
apelin
chr2_-_151971750 0.28 ENST00000636598.1
calcium voltage-gated channel auxiliary subunit beta 4
chr1_+_32251239 0.28 ENST00000373564.7
ENST00000482949.5
ENST00000336890.10
ENST00000495610.6
LCK proto-oncogene, Src family tyrosine kinase
chr19_+_43612083 0.28 ENST00000417606.3
serine/arginine repetitive matrix 5
chrX_+_51893533 0.28 ENST00000375722.5
ENST00000326587.12
ENST00000375695.2
MAGE family member D1
chr11_+_64284982 0.28 ENST00000539833.5
G protein-coupled receptor 137
chr8_+_28494190 0.27 ENST00000537916.2
ENST00000240093.8
ENST00000523546.1
frizzled class receptor 3
chr19_-_54364908 0.27 ENST00000391742.7
leukocyte associated immunoglobulin like receptor 1
chr19_-_54364983 0.27 ENST00000434277.6
leukocyte associated immunoglobulin like receptor 1
chr3_-_132037800 0.27 ENST00000617767.4
copine 4
chr2_-_61471062 0.27 ENST00000398571.7
ubiquitin specific peptidase 34
chr16_+_88706458 0.27 ENST00000312060.9
ENST00000453996.7
ENST00000567949.5
ENST00000564921.1
cytosolic thiouridylase subunit 2
chr9_+_17135017 0.26 ENST00000380641.4
ENST00000380647.8
centlein
chr19_-_54364863 0.26 ENST00000348231.8
leukocyte associated immunoglobulin like receptor 1
chr17_-_42745025 0.26 ENST00000592492.5
ENST00000585893.5
ENST00000593214.5
ENST00000590078.5
ENST00000428826.7
ENST00000586382.5
ENST00000415827.6
ENST00000592743.5
ENST00000586089.5
enhancer of zeste 1 polycomb repressive complex 2 subunit
chr6_+_45422564 0.26 ENST00000625924.1
RUNX family transcription factor 2
chr10_-_50279715 0.26 ENST00000395526.9
N-acylsphingosine amidohydrolase 2
chr3_+_185282941 0.26 ENST00000448876.5
ENST00000446828.5
ENST00000447637.1
ENST00000424227.5
ENST00000454237.1
mitogen-activated protein kinase kinase kinase 13
chr5_+_75512058 0.26 ENST00000514296.5
DNA polymerase kappa
chr3_-_46463648 0.25 ENST00000426532.6
lactotransferrin
chr22_+_31753867 0.25 ENST00000535622.6
ENST00000645693.1
ENST00000642974.1
ENST00000645711.1
ENST00000644331.1
ENST00000645560.1
ENST00000437411.6
ENST00000433147.2
ENST00000646755.1
ENST00000382112.8
ENST00000647438.1
ENST00000400248.7
ENST00000456178.6
ENST00000646969.1
ENST00000642696.1
ENST00000647343.1
ENST00000400242.8
ENST00000651528.2
ENST00000645015.1
ENST00000645564.1
ENST00000646465.1
ENST00000400249.7
DEP domain containing 5, GATOR1 subcomplex subunit
chr9_-_127735286 0.25 ENST00000336067.10
ENST00000373284.10
ENST00000373281.8
ENST00000463577.2
torsin family 2 member A
chr19_+_53521245 0.25 ENST00000649326.1
zinc finger protein 331
chr3_-_49429252 0.25 ENST00000615713.4
nicolin 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.2 GO:0018879 biphenyl metabolic process(GO:0018879)
0.4 1.4 GO:0032474 otolith morphogenesis(GO:0032474)
0.3 1.4 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.3 1.2 GO:0099542 trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.3 0.9 GO:0010933 macrophage tolerance induction(GO:0010931) regulation of macrophage tolerance induction(GO:0010932) positive regulation of macrophage tolerance induction(GO:0010933)
0.3 0.9 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.3 3.3 GO:0006824 cobalt ion transport(GO:0006824)
0.3 0.8 GO:0006393 termination of mitochondrial transcription(GO:0006393)
0.2 1.1 GO:0007412 axon target recognition(GO:0007412)
0.2 1.0 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.2 0.7 GO:0018032 protein amidation(GO:0018032)
0.2 0.5 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.2 2.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.7 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 2.0 GO:0015866 ADP transport(GO:0015866)
0.1 0.4 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 0.8 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1 0.8 GO:0048859 formation of anatomical boundary(GO:0048859)
0.1 0.9 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.4 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.1 1.5 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.9 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.1 0.9 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.4 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.1 1.6 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.1 0.3 GO:0098759 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.1 0.3 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.5 GO:0048294 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.7 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.4 GO:2000983 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)
0.1 0.3 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.1 0.4 GO:0035803 egg coat formation(GO:0035803)
0.1 2.1 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.6 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.1 0.7 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 1.6 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.7 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.2 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.1 0.2 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.1 1.0 GO:0015871 choline transport(GO:0015871)
0.1 0.2 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.1 0.7 GO:0071073 positive regulation of phospholipid biosynthetic process(GO:0071073)
0.1 0.3 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.1 0.4 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.1 0.2 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.1 0.3 GO:1900229 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229) positive regulation of chondrocyte proliferation(GO:1902732)
0.1 2.3 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.1 1.0 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 1.3 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.1 0.2 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.1 0.2 GO:1901143 insulin catabolic process(GO:1901143)
0.1 0.3 GO:0036515 serotonergic neuron axon guidance(GO:0036515) midbrain morphogenesis(GO:1904693)
0.1 0.9 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.2 GO:0014034 neural crest cell fate commitment(GO:0014034) canonical Wnt signaling pathway involved in neural crest cell differentiation(GO:0044335)
0.1 0.3 GO:0071461 cellular response to redox state(GO:0071461)
0.1 4.3 GO:0007602 phototransduction(GO:0007602)
0.1 0.3 GO:0055062 phosphate ion homeostasis(GO:0055062) trivalent inorganic anion homeostasis(GO:0072506)
0.0 0.3 GO:0072423 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.7 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.1 GO:0009946 proximal/distal axis specification(GO:0009946)
0.0 0.2 GO:0046223 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.4 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.6 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.6 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.3 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.2 GO:1902617 response to fluoride(GO:1902617)
0.0 0.3 GO:0060844 arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.0 1.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 1.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.6 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.3 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.7 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.1 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 1.1 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.1 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.0 0.2 GO:1990668 vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane(GO:1990668)
0.0 1.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:0003064 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.2 GO:0035864 response to potassium ion(GO:0035864)
0.0 0.6 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.7 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.8 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.3 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.2 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.5 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.6 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.9 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:0002254 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.0 0.9 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.7 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.8 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.1 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.0 0.1 GO:0072695 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.0 0.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 4.4 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.2 GO:0035356 cellular triglyceride homeostasis(GO:0035356) negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.2 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.3 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 1.2 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.1 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.4 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0002357 defense response to tumor cell(GO:0002357)
0.0 0.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.6 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.0 GO:2000078 positive regulation of type B pancreatic cell development(GO:2000078)
0.0 0.1 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 2.0 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.2 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.1 GO:0032827 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.0 0.2 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0009213 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 0.6 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:0021633 optic nerve structural organization(GO:0021633)
0.0 0.3 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.2 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0040031 snRNA modification(GO:0040031)
0.0 0.3 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.2 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.7 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.0 GO:0060309 elastin catabolic process(GO:0060309)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 1.1 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.7 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 0.1 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.3 GO:0003197 endocardial cushion development(GO:0003197)
0.0 0.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 1.0 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 0.3 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.0 GO:0023058 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401) adaptation of signaling pathway(GO:0023058)
0.0 0.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.3 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.3 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0070765 gamma-secretase complex(GO:0070765)
0.2 0.7 GO:0035517 PR-DUB complex(GO:0035517)
0.2 4.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 1.2 GO:0043196 varicosity(GO:0043196)
0.1 0.9 GO:0044294 dendritic growth cone(GO:0044294)
0.1 1.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 4.7 GO:0030286 dynein complex(GO:0030286)
0.1 0.9 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 2.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.2 GO:1902636 kinociliary basal body(GO:1902636)
0.1 0.5 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.3 GO:0001652 granular component(GO:0001652)
0.1 0.2 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.1 0.3 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.3 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.3 GO:0089701 U2AF(GO:0089701)
0.0 0.3 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.9 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 3.2 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.4 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.3 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 3.8 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 2.1 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 1.4 GO:0005771 multivesicular body(GO:0005771)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.5 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 1.1 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.8 GO:0005657 replication fork(GO:0005657)
0.0 0.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 1.6 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0001939 female pronucleus(GO:0001939) male pronucleus(GO:0001940)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.0 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.3 4.7 GO:0045504 dynein heavy chain binding(GO:0045504)
0.2 3.3 GO:0031419 cobalamin binding(GO:0031419)
0.2 2.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 0.8 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.2 0.9 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.2 0.7 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.9 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 2.0 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 2.1 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.7 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.9 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 2.1 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.3 GO:0019959 interleukin-8 binding(GO:0019959)
0.1 0.6 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 0.9 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.3 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.1 0.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.9 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.1 0.7 GO:0051373 FATZ binding(GO:0051373)
0.1 0.2 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.1 0.2 GO:0031626 beta-endorphin binding(GO:0031626)
0.1 0.7 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1 0.7 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 1.5 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 1.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.2 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.1 0.3 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.3 GO:0036033 mediator complex binding(GO:0036033)
0.1 0.8 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0002046 opsin binding(GO:0002046)
0.0 0.6 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 1.0 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.4 GO:0032190 acrosin binding(GO:0032190)
0.0 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.4 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 1.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.8 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.4 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 1.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 5.5 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.2 GO:0005119 smoothened binding(GO:0005119)
0.0 1.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.0 1.0 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.9 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.3 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.4 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 1.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.5 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.6 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.7 GO:0017136 NAD-dependent histone deacetylase activity(GO:0017136)
0.0 0.2 GO:0048030 disaccharide binding(GO:0048030)
0.0 0.2 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 1.2 GO:0030552 cAMP binding(GO:0030552)
0.0 0.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.4 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.3 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.7 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.6 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.2 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.9 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 1.6 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0016594 glycine binding(GO:0016594)
0.0 1.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.5 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 4.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.9 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.8 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 5.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 2.3 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 1.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.7 PID AURORA A PATHWAY Aurora A signaling
0.0 0.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.3 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.7 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.1 2.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 0.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 0.9 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.2 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.6 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 2.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.7 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 1.0 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.9 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.7 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.7 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.1 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.1 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.3 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors