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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for TCF7L1

Z-value: 0.56

Motif logo

Transcription factors associated with TCF7L1

Gene Symbol Gene ID Gene Info
ENSG00000152284.5 TCF7L1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF7L1hg38_v1_chr2_+_85133376_851334740.374.4e-02Click!

Activity profile of TCF7L1 motif

Sorted Z-values of TCF7L1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF7L1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_205455954 1.86 ENST00000495594.2
ENST00000629624.2
LEM domain containing 1
bladder cancer associated transcript 1
chr12_+_53097656 1.55 ENST00000301464.4
insulin like growth factor binding protein 6
chr10_+_123135938 1.43 ENST00000357878.7
H6 family homeobox 3
chr2_-_207166818 1.05 ENST00000423015.5
Kruppel like factor 7
chr14_+_75280078 0.96 ENST00000555347.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr1_-_6419903 0.92 ENST00000377836.8
ENST00000487437.5
ENST00000489730.1
ENST00000377834.8
hes family bHLH transcription factor 2
chrX_+_136147465 0.89 ENST00000651929.2
four and a half LIM domains 1
chr17_-_41350824 0.85 ENST00000007735.4
keratin 33A
chr10_+_52314272 0.80 ENST00000373970.4
dickkopf WNT signaling pathway inhibitor 1
chr4_-_102345196 0.78 ENST00000683412.1
ENST00000682227.1
solute carrier family 39 member 8
chr4_-_138242325 0.74 ENST00000280612.9
solute carrier family 7 member 11
chr2_+_227813834 0.70 ENST00000358813.5
ENST00000409189.7
C-C motif chemokine ligand 20
chr5_-_157575767 0.68 ENST00000257527.9
ADAM metallopeptidase domain 19
chr11_-_88175432 0.67 ENST00000531138.1
ENST00000526372.1
ENST00000243662.11
RAB38, member RAS oncogene family
chr14_+_32934383 0.65 ENST00000551634.6
neuronal PAS domain protein 3
chrX_-_154371210 0.62 ENST00000369856.8
ENST00000422373.6
ENST00000360319.9
filamin A
chr2_-_207167220 0.61 ENST00000421199.5
ENST00000457962.5
Kruppel like factor 7
chr17_+_77451244 0.59 ENST00000591088.5
septin 9
chr7_-_148884266 0.59 ENST00000483967.5
ENST00000320356.7
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr16_-_46831043 0.58 ENST00000565112.1
chromosome 16 open reading frame 87
chr17_-_41369807 0.56 ENST00000251646.8
keratin 33B
chr17_+_44004604 0.55 ENST00000293404.8
ENST00000589767.1
N-acetylglutamate synthase
chr19_+_40751179 0.54 ENST00000243563.8
ENST00000601393.1
small nuclear ribonucleoprotein polypeptide A
chrX_+_136147556 0.53 ENST00000651089.1
ENST00000420362.5
four and a half LIM domains 1
chr15_+_80404320 0.53 ENST00000303329.9
ENST00000622346.4
aryl hydrocarbon receptor nuclear translocator 2
chr4_+_2818155 0.52 ENST00000511747.6
SH3 domain binding protein 2
chr10_-_24952573 0.52 ENST00000376378.5
ENST00000376376.3
ENST00000320152.11
phosphoribosyl transferase domain containing 1
chr9_-_111038061 0.51 ENST00000358883.8
lysophosphatidic acid receptor 1
chr7_-_148884159 0.50 ENST00000478654.5
ENST00000460911.5
ENST00000350995.6
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr9_+_125748175 0.50 ENST00000491787.7
ENST00000447726.6
PBX homeobox 3
chr1_-_53838276 0.50 ENST00000371429.4
NDC1 transmembrane nucleoporin
chr17_-_7394800 0.49 ENST00000574401.5
phospholipid scramblase 3
chr17_+_9162935 0.49 ENST00000436734.1
netrin 1
chr17_-_7394240 0.49 ENST00000576362.5
ENST00000571078.5
phospholipid scramblase 3
chr10_-_99620401 0.48 ENST00000370495.6
solute carrier family 25 member 28
chr11_-_119729158 0.48 ENST00000264025.8
nectin cell adhesion molecule 1
chr17_-_41055211 0.48 ENST00000542910.1
ENST00000398477.1
keratin associated protein 2-2
chr17_-_7394514 0.46 ENST00000571802.1
ENST00000619711.5
ENST00000576201.5
ENST00000573213.1
ENST00000324822.15
phospholipid scramblase 3
chr7_+_120988683 0.46 ENST00000340646.9
ENST00000310396.10
cadherin like and PC-esterase domain containing 1
chr11_+_69641146 0.45 ENST00000227507.3
ENST00000536559.1
cyclin D1
chr17_-_40937641 0.44 ENST00000209718.8
keratin 23
chr17_+_59155726 0.44 ENST00000578777.5
ENST00000577457.1
ENST00000582995.5
ENST00000262293.9
ENST00000614081.1
proline rich 11
chr17_-_40937445 0.44 ENST00000436344.7
ENST00000485751.1
keratin 23
chr20_+_45881218 0.43 ENST00000372523.1
zinc finger SWIM-type containing 1
chr12_+_15322529 0.43 ENST00000348962.7
protein tyrosine phosphatase receptor type O
chr10_-_86957582 0.42 ENST00000372027.10
multimerin 2
chr17_-_41065879 0.40 ENST00000394015.3
keratin associated protein 2-4
chr6_-_11778781 0.39 ENST00000414691.8
ENST00000229583.9
androgen dependent TFPI regulating protein
chr15_+_81000913 0.39 ENST00000267984.4
talin rod domain containing 1
chr2_-_9003657 0.39 ENST00000462696.1
ENST00000305997.8
membrane bound O-acyltransferase domain containing 2
chr21_+_29299368 0.38 ENST00000399921.5
BTB domain and CNC homolog 1
chr1_-_42958836 0.38 ENST00000372500.4
ENST00000674765.1
ENST00000460369.3
ENST00000426263.10
solute carrier family 2 member 1
chr1_-_93614091 0.37 ENST00000370247.7
BCAR3 adaptor protein, NSP family member
chr9_+_136327526 0.37 ENST00000440944.6
G protein signaling modulator 1
chr19_-_11339573 0.36 ENST00000222120.8
RAB3D, member RAS oncogene family
chr12_+_70366277 0.36 ENST00000258111.5
potassium calcium-activated channel subfamily M regulatory beta subunit 4
chr1_+_81800368 0.36 ENST00000674489.1
ENST00000674442.1
ENST00000674419.1
ENST00000674407.1
ENST00000674168.1
ENST00000674307.1
ENST00000674209.1
ENST00000370715.5
ENST00000370713.5
ENST00000319517.10
ENST00000627151.2
ENST00000370717.6
adhesion G protein-coupled receptor L2
chr14_+_105474781 0.35 ENST00000550577.5
ENST00000538259.2
ENST00000329146.9
cysteine rich protein 2
chr7_+_111091006 0.35 ENST00000451085.5
ENST00000422987.3
ENST00000421101.1
leucine rich repeat neuronal 3
chr12_-_107761113 0.35 ENST00000228437.10
PR/SET domain 4
chr3_-_57165332 0.33 ENST00000296318.12
interleukin 17 receptor D
chr7_-_27180230 0.33 ENST00000396344.4
homeobox A10
chr9_-_111038037 0.33 ENST00000374431.7
lysophosphatidic acid receptor 1
chr14_-_64942783 0.33 ENST00000612794.1
glutathione peroxidase 2
chr19_+_48364361 0.33 ENST00000344846.7
synaptogyrin 4
chr9_+_100427254 0.32 ENST00000374885.5
Myb/SANT DNA binding domain containing 3
chr17_+_82458174 0.32 ENST00000579198.5
ENST00000390006.8
ENST00000580296.5
nuclear prelamin A recognition factor
chr9_-_111038425 0.31 ENST00000441240.1
ENST00000683809.1
lysophosphatidic acid receptor 1
chr2_-_9630946 0.31 ENST00000446619.1
ENST00000238081.8
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
chr19_-_40285395 0.31 ENST00000424901.5
ENST00000578123.5
AKT serine/threonine kinase 2
chr19_-_40285277 0.30 ENST00000579047.5
ENST00000392038.7
AKT serine/threonine kinase 2
chr7_+_80646305 0.30 ENST00000426978.5
ENST00000432207.5
CD36 molecule
chr7_+_111091119 0.30 ENST00000308478.10
leucine rich repeat neuronal 3
chr10_+_52128343 0.29 ENST00000672084.1
protein kinase cGMP-dependent 1
chr3_-_197298092 0.29 ENST00000392382.6
discs large MAGUK scaffold protein 1
chr9_+_113463697 0.28 ENST00000317613.10
regulator of G protein signaling 3
chr14_-_73027077 0.28 ENST00000553891.5
ENST00000556143.6
zinc finger FYVE-type containing 1
chr19_-_49361475 0.28 ENST00000598810.5
TEA domain transcription factor 2
chr12_-_109477293 0.28 ENST00000228495.11
ENST00000542858.1
ENST00000542262.5
potassium channel tetramerization domain containing 10
chr5_+_132257670 0.28 ENST00000253754.8
ENST00000379018.7
PDZ and LIM domain 4
chr21_-_30813270 0.28 ENST00000329621.6
keratin associated protein 8-1
chr14_-_73027117 0.27 ENST00000318876.9
zinc finger FYVE-type containing 1
chr18_-_26865732 0.27 ENST00000672188.1
aquaporin 4
chr12_+_55931148 0.27 ENST00000549629.5
ENST00000555218.5
ENST00000331886.10
diacylglycerol kinase alpha
chr8_-_143973520 0.27 ENST00000356346.7
plectin
chr7_-_106661148 0.26 ENST00000523505.3
coiled-coil domain containing 71 like
chr18_-_26865689 0.26 ENST00000675739.1
ENST00000383168.9
ENST00000672981.2
ENST00000578776.1
aquaporin 4
chr1_+_109548567 0.26 ENST00000369851.7
G protein subunit alpha i3
chrX_-_43973382 0.26 ENST00000642620.1
ENST00000647044.1
norrin cystine knot growth factor NDP
chr15_+_62066975 0.26 ENST00000355522.5
C2 calcium dependent domain containing 4A
chr7_+_80646436 0.26 ENST00000419819.2
CD36 molecule
chr10_-_97292625 0.26 ENST00000466484.1
ENST00000358531.9
ENST00000358308.7
Rho GTPase activating protein 19
chr19_-_58519751 0.26 ENST00000600990.1
ENST00000594051.6
zinc finger and BTB domain containing 45
chr20_-_675793 0.26 ENST00000488788.2
ENST00000246104.7
novel protein
scratch family transcriptional repressor 2
chr2_-_240896144 0.25 ENST00000388934.5
mab-21 like 4
chr17_+_82458649 0.25 ENST00000345415.11
ENST00000412079.6
ENST00000457415.7
ENST00000584411.5
ENST00000577432.5
nuclear prelamin A recognition factor
chr3_+_189631373 0.25 ENST00000264731.8
ENST00000418709.6
ENST00000320472.9
ENST00000392460.7
ENST00000440651.6
tumor protein p63
chr16_-_9943182 0.25 ENST00000535259.6
glutamate ionotropic receptor NMDA type subunit 2A
chr3_-_197297523 0.24 ENST00000434148.1
ENST00000412364.2
ENST00000661013.1
ENST00000666007.1
ENST00000422288.6
ENST00000456699.6
ENST00000392380.6
ENST00000670935.1
ENST00000656087.1
ENST00000436682.6
ENST00000662727.1
ENST00000670455.1
ENST00000659221.1
ENST00000671185.1
ENST00000669565.1
ENST00000660898.1
ENST00000667971.1
ENST00000661453.1
discs large MAGUK scaffold protein 1
chr3_-_197298558 0.24 ENST00000656944.1
ENST00000346964.6
ENST00000448528.6
ENST00000655488.1
ENST00000357674.9
ENST00000667157.1
ENST00000661336.1
ENST00000654737.1
ENST00000659716.1
ENST00000657381.1
discs large MAGUK scaffold protein 1
chr11_+_19712823 0.24 ENST00000396085.6
ENST00000349880.9
neuron navigator 2
chr5_-_157575741 0.24 ENST00000517905.1
ADAM metallopeptidase domain 19
chr3_-_197298000 0.24 ENST00000664991.1
discs large MAGUK scaffold protein 1
chr8_+_38787218 0.24 ENST00000317827.9
ENST00000276520.12
transforming acidic coiled-coil containing protein 1
chr14_+_23376765 0.23 ENST00000649278.1
CKLF like MARVEL transmembrane domain containing 5
chr7_-_151814636 0.22 ENST00000652047.1
ENST00000650858.1
protein kinase AMP-activated non-catalytic subunit gamma 2
chr19_+_10960955 0.22 ENST00000642628.1
ENST00000643296.1
ENST00000647230.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr2_+_9843426 0.22 ENST00000625239.2
ENST00000263663.10
TATA-box binding protein associated factor, RNA polymerase I subunit B
chr19_-_58519554 0.22 ENST00000354590.7
ENST00000596739.1
zinc finger and BTB domain containing 45
chr20_-_17531366 0.22 ENST00000377873.8
beaded filament structural protein 1
chr13_+_31945826 0.22 ENST00000647500.1
FRY microtubule binding protein
chr7_-_151814668 0.22 ENST00000651764.1
protein kinase AMP-activated non-catalytic subunit gamma 2
chr16_-_46831134 0.21 ENST00000394806.6
ENST00000285697.9
chromosome 16 open reading frame 87
chr13_+_39038347 0.21 ENST00000379599.6
ENST00000379600.8
NHL repeat containing 3
chr14_+_57390544 0.21 ENST00000555166.5
ENST00000556492.6
ENST00000554703.1
N-alpha-acetyltransferase 30, NatC catalytic subunit
chr17_-_39607876 0.21 ENST00000302584.5
neuronal differentiation 2
chr7_+_80602200 0.21 ENST00000534394.5
CD36 molecule
chr4_+_77157189 0.21 ENST00000316355.10
ENST00000502280.5
cyclin G2
chr19_+_10960976 0.21 ENST00000646510.1
ENST00000429416.8
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr14_+_23376786 0.21 ENST00000359320.7
CKLF like MARVEL transmembrane domain containing 5
chr19_+_10960917 0.20 ENST00000643549.1
ENST00000642726.1
ENST00000646484.1
ENST00000644737.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr6_+_20403679 0.20 ENST00000535432.2
E2F transcription factor 3
chr1_+_15684284 0.20 ENST00000375799.8
ENST00000375793.2
pleckstrin homology and RUN domain containing M2
chr8_+_119067239 0.20 ENST00000332843.3
collectin subfamily member 10
chr7_+_80602150 0.20 ENST00000309881.11
CD36 molecule
chr12_+_32107296 0.20 ENST00000551086.1
BICD cargo adaptor 1
chr1_+_47333863 0.20 ENST00000471289.2
ENST00000450808.2
cytidine/uridine monophosphate kinase 1
chr2_-_165204042 0.20 ENST00000283254.12
ENST00000453007.1
sodium voltage-gated channel alpha subunit 3
chr14_+_23377001 0.20 ENST00000342473.8
ENST00000397227.7
ENST00000339180.9
ENST00000555731.5
CKLF like MARVEL transmembrane domain containing 5
chrX_-_32155462 0.19 ENST00000359836.5
ENST00000378707.7
ENST00000541735.5
ENST00000684130.1
ENST00000682238.1
ENST00000620040.5
ENST00000474231.5
dystrophin
chr7_-_27174274 0.19 ENST00000283921.5
homeobox A10
chr5_-_16936231 0.19 ENST00000507288.1
ENST00000274203.13
ENST00000513610.6
myosin X
chr2_-_17800195 0.19 ENST00000402989.5
ENST00000428868.1
structural maintenance of chromosomes 6
chr3_+_133038366 0.19 ENST00000321871.11
ENST00000393130.7
ENST00000514894.5
ENST00000512662.5
transmembrane protein 108
chr17_+_32486975 0.19 ENST00000313401.4
cyclin dependent kinase 5 regulatory subunit 1
chr12_+_54008961 0.18 ENST00000040584.6
homeobox C8
chr17_-_39864304 0.18 ENST00000346872.8
IKAROS family zinc finger 3
chr7_-_27174253 0.18 ENST00000613671.1
homeobox A10
chr6_+_63571702 0.17 ENST00000672924.1
protein tyrosine phosphatase 4A1
chr17_-_39864140 0.17 ENST00000623724.3
ENST00000439167.6
ENST00000377945.7
ENST00000394189.6
ENST00000377944.7
ENST00000377958.6
ENST00000535189.5
ENST00000377952.6
IKAROS family zinc finger 3
chr2_-_165203870 0.17 ENST00000639244.1
ENST00000409101.7
ENST00000668657.1
sodium voltage-gated channel alpha subunit 3
chr13_+_75636311 0.17 ENST00000377499.9
ENST00000377534.8
LIM domain 7
chr12_+_103965863 0.17 ENST00000392872.8
ENST00000537100.5
thymine DNA glycosylase
chr2_-_9630491 0.17 ENST00000381844.8
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
chr13_+_39038292 0.17 ENST00000470258.5
NHL repeat containing 3
chr2_+_169066994 0.17 ENST00000357546.6
ENST00000432060.6
dehydrogenase/reductase 9
chr17_+_47522931 0.17 ENST00000525007.5
ENST00000530173.6
aminopeptidase puromycin sensitive
chr12_+_101666203 0.16 ENST00000549608.1
myosin binding protein C1
chrX_+_47078330 0.16 ENST00000457380.5
regucalcin
chr1_+_8318088 0.16 ENST00000471889.7
solute carrier family 45 member 1
chr8_-_33567118 0.16 ENST00000256257.2
ring finger protein 122
chrX_+_47078434 0.16 ENST00000397180.6
regucalcin
chr6_-_106975616 0.16 ENST00000610952.1
CD24 molecule
chr6_+_35737078 0.16 ENST00000288065.6
armadillo repeat containing 12
chr6_-_151391539 0.16 ENST00000325144.5
zinc finger and BTB domain containing 2
chr6_-_33580229 0.16 ENST00000374467.4
ENST00000442998.6
ENST00000360661.9
BCL2 antagonist/killer 1
chr5_-_59039454 0.15 ENST00000358923.10
phosphodiesterase 4D
chr8_-_123541197 0.15 ENST00000517956.5
ENST00000443022.2
F-box protein 32
chr1_+_77918128 0.15 ENST00000342754.5
nexilin F-actin binding protein
chr9_-_120926752 0.15 ENST00000373887.8
TNF receptor associated factor 1
chr6_+_35737028 0.15 ENST00000373869.7
ENST00000373866.4
armadillo repeat containing 12
chr1_+_180230257 0.15 ENST00000263726.4
LIM homeobox 4
chr7_+_100733576 0.15 ENST00000613979.5
ENST00000620596.4
zonadhesin
chr20_-_13990609 0.15 ENST00000284951.10
ENST00000378072.5
SEL1L2 adaptor subunit of ERAD E3 ligase
chr11_-_10808304 0.15 ENST00000532082.6
eukaryotic translation initiation factor 4 gamma 2
chr11_+_65572349 0.14 ENST00000316409.2
ENST00000449319.2
ENST00000530349.2
family with sequence similarity 89 member B
chr9_-_23826299 0.14 ENST00000380117.5
ELAV like RNA binding protein 2
chr18_+_32190015 0.14 ENST00000581447.1
meprin A subunit beta
chr15_+_75843307 0.14 ENST00000569423.5
ubiquitin conjugating enzyme E2 Q2
chrX_+_47078380 0.14 ENST00000352078.8
regucalcin
chr18_+_32190033 0.14 ENST00000269202.11
meprin A subunit beta
chr15_+_78438279 0.14 ENST00000560440.5
iron responsive element binding protein 2
chr17_+_7630094 0.14 ENST00000441599.6
ENST00000380450.9
ENST00000416273.7
ENST00000575903.5
ENST00000571153.5
ENST00000575618.5
ENST00000576152.1
ENST00000576830.5
sex hormone binding globulin
chr2_+_233778330 0.14 ENST00000389758.3
maestro heat like repeat family member 2A
chr9_-_35650902 0.14 ENST00000259608.8
ENST00000618781.1
signaling threshold regulating transmembrane adaptor 1
chr6_-_106975309 0.13 ENST00000615659.1
CD24 molecule
chr7_-_19773569 0.13 ENST00000422233.5
ENST00000433641.5
ENST00000405844.6
transmembrane protein 196
chr12_-_103965689 0.13 ENST00000553183.5
chromosome 12 open reading frame 73
chr8_-_101206064 0.13 ENST00000518336.5
ENST00000520454.1
zinc finger protein 706
chr7_+_116210501 0.13 ENST00000455989.1
ENST00000358204.9
testin LIM domain protein
chr15_-_89221558 0.13 ENST00000268125.10
retinaldehyde binding protein 1
chr1_-_109393197 0.12 ENST00000538502.5
ENST00000482236.5
sortilin 1
chr14_-_74019255 0.12 ENST00000334696.11
ENST00000556242.5
ectonucleoside triphosphate diphosphohydrolase 5 (inactive)
chr5_+_66828762 0.11 ENST00000490016.6
ENST00000403666.5
ENST00000450827.5
microtubule associated serine/threonine kinase family member 4
chr15_+_75843438 0.11 ENST00000267938.9
ubiquitin conjugating enzyme E2 Q2
chr10_-_102432565 0.11 ENST00000369937.5
CUE domain containing 2
chr21_-_32771664 0.11 ENST00000290178.4
PAX3 and PAX7 binding protein 1
chr11_-_95232514 0.11 ENST00000634898.1
ENST00000542176.1
ENST00000278499.6
sestrin 3
chr4_-_7939789 0.11 ENST00000420658.6
ENST00000358461.6
actin filament associated protein 1
chr2_+_97669739 0.11 ENST00000599501.6
ENST00000627399.3
ENST00000627284.2
ENST00000599435.5
ENST00000597654.5
ENST00000598737.5
chromosome 2 open reading frame 92
chr2_-_37324826 0.11 ENST00000234179.8
protein kinase D3
chrX_+_106920393 0.11 ENST00000336803.2
claudin 2
chr12_+_32107151 0.10 ENST00000548411.5
BICD cargo adaptor 1
chr7_-_25228485 0.10 ENST00000222674.2
neuropeptide VF precursor
chr1_-_11691608 0.10 ENST00000376667.7
mitotic arrest deficient 2 like 2
chr5_+_72816643 0.10 ENST00000337273.10
ENST00000523768.5
transportin 1
chr10_-_125775821 0.10 ENST00000368808.3
matrix metallopeptidase 21
chr2_+_26848424 0.10 ENST00000431402.5
ENST00000614712.4
ENST00000434719.1
dihydropyrimidinase like 5
chr6_+_95577465 0.10 ENST00000369293.6
ENST00000683151.1
ENST00000358812.9
mannosidase endo-alpha
chr2_+_69013337 0.10 ENST00000463335.2
ANTXR cell adhesion molecule 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.3 0.8 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.2 0.7 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.2 1.1 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.2 0.6 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.2 0.6 GO:0071484 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) retinal cell apoptotic process(GO:1990009)
0.2 0.5 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.2 0.5 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.1 0.4 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.1 0.4 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.5 GO:1903629 regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634)
0.1 0.7 GO:1903232 melanosome assembly(GO:1903232)
0.1 1.0 GO:2000334 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.4 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 1.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.4 GO:0032595 B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
0.1 0.4 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.5 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.8 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 0.3 GO:1900737 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.1 0.2 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1 0.6 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.1 1.0 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.2 GO:0021722 pons maturation(GO:0021586) superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.2 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 1.4 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.2 GO:0051230 mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.1 0.5 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 0.5 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.2 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.1 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of RNA export from nucleus(GO:0046833)
0.1 0.2 GO:0002339 B cell selection(GO:0002339)
0.1 0.2 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.2 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.0 0.2 GO:0033058 directional locomotion(GO:0033058)
0.0 0.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.3 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.2 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 1.5 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.2 GO:0021564 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.0 0.5 GO:0002934 desmosome organization(GO:0002934)
0.0 0.2 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.3 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.4 GO:0070141 Leydig cell differentiation(GO:0033327) response to UV-A(GO:0070141)
0.0 0.3 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.2 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.4 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.7 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.5 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.0 0.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 1.4 GO:0007566 embryo implantation(GO:0007566)
0.0 0.5 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.4 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.0 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.2 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.7 GO:0060065 uterus development(GO:0060065)
0.0 3.5 GO:0031424 keratinization(GO:0031424)
0.0 0.6 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 1.0 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.5 GO:0006833 water transport(GO:0006833)
0.0 1.1 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.3 GO:0030903 notochord development(GO:0030903)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989) regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.4 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.1 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.4 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 0.7 GO:0031905 early endosome lumen(GO:0031905)
0.1 1.5 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.6 GO:0031523 Myb complex(GO:0031523)
0.1 1.0 GO:0035976 AP1 complex(GO:0035976)
0.1 1.5 GO:0045120 pronucleus(GO:0045120)
0.1 0.3 GO:0039714 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.1 0.3 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.5 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.5 GO:0005816 spindle pole body(GO:0005816)
0.1 1.0 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.2 GO:0031417 NatC complex(GO:0031417)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.6 GO:0042588 zymogen granule(GO:0042588)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.5 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.0 GO:0044094 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.0 3.5 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 1.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.0 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.2 0.7 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.1 0.7 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 1.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 1.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 0.6 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 1.0 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.5 GO:0004341 gluconolactonase activity(GO:0004341)
0.1 0.5 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.5 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.4 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.4 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.1 1.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 0.2 GO:0030350 iron-responsive element binding(GO:0030350)
0.1 0.2 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1 1.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.2 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 1.0 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.8 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.3 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.2 GO:0002046 opsin binding(GO:0002046)
0.0 0.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.9 GO:0001164 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.4 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.5 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.5 GO:0046790 virion binding(GO:0046790)
0.0 0.4 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.1 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0 0.5 GO:0015250 water channel activity(GO:0015250)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.6 GO:0043325 1-phosphatidylinositol binding(GO:0005545) phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.3 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022) testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.7 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.1 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.5 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.4 PID IL2 1PATHWAY IL2-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.0 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.7 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.2 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines