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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for TFAP2B

Z-value: 0.69

Motif logo

Transcription factors associated with TFAP2B

Gene Symbol Gene ID Gene Info
ENSG00000008196.13 TFAP2B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFAP2Bhg38_v1_chr6_+_50818701_508187230.202.8e-01Click!

Activity profile of TFAP2B motif

Sorted Z-values of TFAP2B motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP2B

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_+_149141817 1.58 ENST00000504238.5
actin binding LIM protein family member 3
chr5_+_149141483 1.51 ENST00000326685.11
ENST00000309868.12
actin binding LIM protein family member 3
chr5_+_149141573 1.48 ENST00000506113.5
actin binding LIM protein family member 3
chr12_-_89352395 1.13 ENST00000308385.6
dual specificity phosphatase 6
chr12_-_89352487 1.03 ENST00000548755.1
ENST00000279488.8
dual specificity phosphatase 6
chr1_+_152908538 0.96 ENST00000368764.4
involucrin
chr11_-_61581104 0.95 ENST00000263846.8
synaptotagmin 7
chr19_-_11578937 0.93 ENST00000592659.1
ENST00000592828.6
ENST00000218758.9
ENST00000412435.6
acid phosphatase 5, tartrate resistant
chr14_+_94174284 0.85 ENST00000304338.8
protein phosphatase 4 regulatory subunit 4
chr9_+_87498491 0.73 ENST00000622514.4
death associated protein kinase 1
chr21_-_26845402 0.70 ENST00000284984.8
ENST00000676955.1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr1_+_17249088 0.70 ENST00000375460.3
peptidyl arginine deiminase 3
chr14_+_64704380 0.66 ENST00000247226.13
ENST00000394691.7
pleckstrin homology and RhoGEF domain containing G3
chr17_-_5234801 0.64 ENST00000571800.5
ENST00000574081.6
ENST00000399600.8
ENST00000574297.1
SLP adaptor and CSK interacting membrane protein
chr1_-_20486197 0.64 ENST00000375078.4
calcium/calmodulin dependent protein kinase II inhibitor 1
chr1_-_74732997 0.62 ENST00000370872.7
ENST00000370871.7
ENST00000340866.10
ENST00000370870.5
crystallin zeta
chr1_-_74733253 0.60 ENST00000417775.5
crystallin zeta
chr9_+_87497852 0.57 ENST00000408954.8
death associated protein kinase 1
chr19_+_35154715 0.56 ENST00000392218.6
ENST00000543307.5
ENST00000392219.7
ENST00000541435.6
ENST00000590686.5
ENST00000342879.7
ENST00000588699.5
FXYD domain containing ion transport regulator 5
chr2_+_95346649 0.56 ENST00000468529.1
potassium voltage-gated channel interacting protein 3
chr20_+_63696643 0.56 ENST00000369996.3
TNF receptor superfamily member 6b
chr8_-_143572748 0.56 ENST00000529971.1
ENST00000398882.8
maestro heat like repeat family member 6
chr19_+_35154914 0.56 ENST00000423817.7
FXYD domain containing ion transport regulator 5
chr11_-_68213828 0.54 ENST00000405515.5
lysine methyltransferase 5B
chr1_+_155208727 0.54 ENST00000316721.8
metaxin 1
chr19_+_50203607 0.54 ENST00000642316.2
ENST00000425460.6
ENST00000440075.6
ENST00000376970.6
ENST00000599920.5
myosin heavy chain 14
chr9_+_17579059 0.54 ENST00000380607.5
SH3 domain containing GRB2 like 2, endophilin A1
chr1_+_7784411 0.53 ENST00000613533.4
ENST00000614998.4
period circadian regulator 3
chr17_+_45620323 0.53 ENST00000634540.1
LINC02210-CRHR1 readthrough
chr14_+_54567100 0.51 ENST00000554335.6
sterile alpha motif domain containing 4A
chr18_+_3449413 0.51 ENST00000549253.5
TGFB induced factor homeobox 1
chr22_+_31082860 0.49 ENST00000619644.4
smoothelin
chr1_+_155033824 0.49 ENST00000295542.6
ENST00000423025.6
ENST00000368419.2
DC-STAMP domain containing 1
chr2_-_207165923 0.49 ENST00000309446.11
Kruppel like factor 7
chr1_+_155208690 0.49 ENST00000368376.8
metaxin 1
chr14_+_79279906 0.49 ENST00000428277.6
neurexin 3
chr14_+_79279403 0.48 ENST00000281127.11
neurexin 3
chr14_+_94174334 0.48 ENST00000328839.3
protein phosphatase 4 regulatory subunit 4
chr11_+_126355634 0.48 ENST00000227495.10
ENST00000676545.1
ENST00000678865.1
ENST00000444328.7
ENST00000677503.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr11_-_68213577 0.46 ENST00000402789.5
ENST00000402185.6
ENST00000458496.1
lysine methyltransferase 5B
chr15_-_79090760 0.44 ENST00000419573.7
ENST00000558480.7
Ras protein specific guanine nucleotide releasing factor 1
chr11_-_7673485 0.44 ENST00000299498.11
cytochrome b5 reductase 2
chr16_+_30949054 0.44 ENST00000318663.5
ENST00000566237.1
ENST00000562699.1
ORAI calcium release-activated calcium modulator 3
chr3_-_197029775 0.44 ENST00000439320.1
ENST00000296351.8
ENST00000296350.10
melanotransferrin
chr4_+_94489030 0.43 ENST00000510099.5
PDZ and LIM domain 5
chr1_+_155209213 0.43 ENST00000609421.1
metaxin 1
chr11_-_66336396 0.42 ENST00000627248.1
ENST00000311320.9
Ras and Rab interactor 1
chr14_+_93927358 0.42 ENST00000557000.2
family with sequence similarity 181 member A
chr11_+_126355894 0.41 ENST00000530591.5
ENST00000534083.5
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr5_+_170353480 0.41 ENST00000377360.8
potassium voltage-gated channel interacting protein 1
chr19_+_1067144 0.41 ENST00000313093.7
Rho GTPase activating protein 45
chr19_+_1067272 0.41 ENST00000590214.5
Rho GTPase activating protein 45
chr19_+_1067493 0.40 ENST00000586866.5
Rho GTPase activating protein 45
chr16_+_30896606 0.40 ENST00000279804.3
ENST00000395019.3
cardiotrophin 1
chr11_-_7674206 0.39 ENST00000533558.5
ENST00000527542.5
cytochrome b5 reductase 2
chr4_+_1721470 0.39 ENST00000612220.5
ENST00000313288.9
transforming acidic coiled-coil containing protein 3
chr15_+_58771280 0.37 ENST00000559228.6
ENST00000450403.3
MINDY lysine 48 deubiquitinase 2
chr3_-_52231190 0.37 ENST00000494383.1
novel twinfilin, actin-binding protein, homolog 2 (Drosophila) (TWF2) and toll-like receptor 9 (TLR9) protein
chr21_+_42219123 0.37 ENST00000398449.8
ATP binding cassette subfamily G member 1
chr20_+_6767678 0.37 ENST00000378827.5
bone morphogenetic protein 2
chr9_+_121651594 0.36 ENST00000408936.7
DAB2 interacting protein
chr1_+_31576485 0.36 ENST00000457433.6
ENST00000271064.12
tubulointerstitial nephritis antigen like 1
chr10_+_69318831 0.35 ENST00000359426.7
hexokinase 1
chr11_+_61228377 0.35 ENST00000537932.5
pepsinogen A4
chr21_+_42219111 0.35 ENST00000450121.5
ENST00000361802.6
ATP binding cassette subfamily G member 1
chr6_-_30686624 0.35 ENST00000274853.8
protein phosphatase 1 regulatory subunit 18
chr19_+_10718114 0.35 ENST00000408974.8
dynamin 2
chr7_-_100468063 0.35 ENST00000423266.5
ENST00000456330.1
TSC22 domain family member 4
chr1_-_25906457 0.33 ENST00000426559.6
stathmin 1
chr2_+_200440649 0.33 ENST00000366118.2
spermatogenesis associated serine rich 2 like
chrX_+_7147675 0.33 ENST00000674429.1
steroid sulfatase
chrX_-_46759055 0.33 ENST00000328306.4
ENST00000616978.5
solute carrier family 9 member A7
chr10_-_98030612 0.33 ENST00000370597.8
cartilage acidic protein 1
chr1_+_11934651 0.33 ENST00000449038.5
ENST00000196061.5
ENST00000429000.6
procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
chr15_-_74209019 0.33 ENST00000323940.9
signaling receptor and transporter of retinol STRA6
chr2_-_219309484 0.33 ENST00000409251.7
ENST00000451506.5
ENST00000446182.5
protein tyrosine phosphatase receptor type N
chr19_+_40601342 0.32 ENST00000396819.8
latent transforming growth factor beta binding protein 4
chr17_-_45425620 0.32 ENST00000376922.6
Rho GTPase activating protein 27
chr16_+_2964216 0.32 ENST00000572045.5
ENST00000571007.5
ENST00000575885.5
ENST00000303746.10
ENST00000319500.10
kringle containing transmembrane protein 2
chr10_-_70170466 0.32 ENST00000373239.2
ENST00000373241.9
ENST00000373242.6
secretion associated Ras related GTPase 1A
chr6_-_30687200 0.32 ENST00000399199.7
protein phosphatase 1 regulatory subunit 18
chr10_+_133527355 0.31 ENST00000252945.8
ENST00000421586.5
ENST00000418356.1
cytochrome P450 family 2 subfamily E member 1
chr1_-_237004440 0.31 ENST00000464121.3
metallothionein 1H like 1
chr13_+_20703677 0.31 ENST00000682841.1
interleukin 17D
chr9_-_120877026 0.31 ENST00000436309.5
PHD finger protein 19
chr1_+_206507546 0.31 ENST00000580449.5
ENST00000581503.6
Ras association domain family member 5
chr16_-_636253 0.30 ENST00000565163.5
methyltransferase like 26
chr17_-_43778937 0.30 ENST00000226004.8
dual specificity phosphatase 3
chrX_+_7147237 0.29 ENST00000666110.2
steroid sulfatase
chr2_-_227164194 0.29 ENST00000396625.5
collagen type IV alpha 4 chain
chr15_-_25865076 0.29 ENST00000619904.1
ATPase phospholipid transporting 10A (putative)
chr12_+_112418889 0.29 ENST00000392597.5
protein tyrosine phosphatase non-receptor type 11
chr9_+_128420812 0.29 ENST00000372838.9
cerebral endothelial cell adhesion molecule
chr11_+_73289403 0.29 ENST00000535931.2
ENST00000544437.6
pyrimidinergic receptor P2Y6
chr9_+_131289685 0.29 ENST00000372264.4
phospholipid phosphatase 7 (inactive)
chr2_-_219309350 0.29 ENST00000295718.7
protein tyrosine phosphatase receptor type N
chr8_-_142786530 0.29 ENST00000301263.5
lymphocyte antigen 6 family member D
chr1_+_206507520 0.28 ENST00000579436.7
Ras association domain family member 5
chr20_-_46308485 0.28 ENST00000537909.4
cadherin 22
chr8_-_141001217 0.28 ENST00000522684.5
ENST00000524357.5
ENST00000521332.5
ENST00000524040.5
ENST00000519881.5
ENST00000520045.5
protein tyrosine kinase 2
chr8_-_143973520 0.28 ENST00000356346.7
plectin
chr6_+_33410961 0.28 ENST00000374512.7
ENST00000374516.8
PHD finger protein 1
chr2_-_27263034 0.28 ENST00000233535.9
solute carrier family 30 member 3
chr11_-_61580826 0.28 ENST00000540677.5
ENST00000542836.5
ENST00000542670.5
ENST00000535826.5
ENST00000545053.1
ENST00000539008.6
synaptotagmin 7
chrX_+_132023580 0.27 ENST00000496850.1
serine/threonine kinase 26
chr5_+_150601060 0.27 ENST00000394243.5
synaptopodin
chr11_+_43942627 0.27 ENST00000617612.3
chromosome 11 open reading frame 96
chr5_-_177303675 0.27 ENST00000393611.6
ENST00000303270.6
ENST00000303251.11
RAB24, member RAS oncogene family
chr13_-_19863508 0.27 ENST00000382907.8
ENST00000382905.8
zinc finger MYM-type containing 5
chr12_-_52796110 0.27 ENST00000417996.2
keratin 3
chr16_-_636270 0.27 ENST00000397665.6
ENST00000397666.6
ENST00000301686.13
ENST00000338401.8
ENST00000397664.8
ENST00000568830.1
ENST00000614890.4
methyltransferase like 26
chr22_+_18529042 0.26 ENST00000613577.4
transmembrane protein 191B
chr19_-_42242526 0.26 ENST00000222330.8
ENST00000676537.1
glycogen synthase kinase 3 alpha
chr1_-_204213943 0.26 ENST00000308302.4
golgi transport 1A
chr21_+_43728851 0.26 ENST00000327574.4
pyridoxal kinase
chr13_-_21459226 0.26 ENST00000320220.13
zinc finger DHHC-type palmitoyltransferase 20
chr19_-_1822038 0.26 ENST00000643515.1
RNA exonuclease 1 homolog
chr16_-_71289609 0.25 ENST00000338099.9
ENST00000563876.1
cap methyltransferase 2
chr17_-_48037760 0.25 ENST00000621465.5
COPI coat complex subunit zeta 2
chr14_+_79279339 0.25 ENST00000557594.5
neurexin 3
chr14_+_79279681 0.25 ENST00000679122.1
neurexin 3
chr14_-_91253925 0.25 ENST00000531499.2
G protein-coupled receptor 68
chr1_+_178725147 0.25 ENST00000367634.6
Ral GEF with PH domain and SH3 binding motif 2
chr19_-_55149193 0.25 ENST00000587758.5
ENST00000588981.6
ENST00000356783.9
ENST00000291901.12
ENST00000588426.5
ENST00000536926.5
ENST00000588147.5
troponin T1, slow skeletal type
chr10_+_11005301 0.25 ENST00000416382.6
ENST00000631460.1
ENST00000631816.1
CUGBP Elav-like family member 2
chr3_+_100492548 0.25 ENST00000323523.8
ENST00000403410.5
ENST00000449609.1
transmembrane protein 45A
chr9_-_34522968 0.24 ENST00000399775.3
energy homeostasis associated
chr12_+_131894615 0.24 ENST00000321867.6
unc-51 like autophagy activating kinase 1
chr5_+_172641241 0.24 ENST00000369800.6
ENST00000520919.5
ENST00000522853.5
neuralized E3 ubiquitin protein ligase 1B
chr1_-_27012837 0.24 ENST00000289166.6
terminal nucleotidyltransferase 5B
chr5_+_150190035 0.24 ENST00000230671.7
ENST00000524041.1
solute carrier family 6 member 7
chr17_-_80476597 0.24 ENST00000306773.5
neuronal pentraxin 1
chr17_-_5584448 0.24 ENST00000269280.8
ENST00000571451.6
ENST00000572272.6
ENST00000613500.4
ENST00000619223.4
ENST00000617618.4
ENST00000345221.7
ENST00000262467.10
NLR family pyrin domain containing 1
chr19_+_45467988 0.24 ENST00000615753.4
ENST00000585836.5
ENST00000417353.6
ENST00000591858.5
ENST00000443841.6
ENST00000590335.1
ENST00000353609.8
FosB proto-oncogene, AP-1 transcription factor subunit
chr14_-_93115812 0.24 ENST00000553452.5
inositol-tetrakisphosphate 1-kinase
chrX_+_49058966 0.24 ENST00000496529.6
ENST00000606812.5
ENST00000603986.6
ENST00000536628.3
coiled-coil domain containing 120
chr8_-_143944737 0.24 ENST00000398774.6
plectin
chr10_+_18400562 0.23 ENST00000377315.5
ENST00000650685.1
calcium voltage-gated channel auxiliary subunit beta 2
chr1_+_178725227 0.23 ENST00000367635.8
Ral GEF with PH domain and SH3 binding motif 2
chr19_+_41443130 0.23 ENST00000378187.3
glutamate rich 4
chr22_-_18024513 0.23 ENST00000441493.7
microtubule associated monooxygenase, calponin and LIM domain containing 3
chrX_+_69504320 0.23 ENST00000252338.5
family with sequence similarity 155 member B
chr16_+_2817230 0.23 ENST00000005995.8
ENST00000574813.5
serine protease 21
chr16_-_71289367 0.23 ENST00000434935.7
ENST00000565850.1
ENST00000568910.1
cap methyltransferase 2
chr2_+_184598520 0.23 ENST00000302277.7
zinc finger protein 804A
chr9_-_120877167 0.23 ENST00000373896.8
ENST00000312189.10
PHD finger protein 19
chr1_+_45326869 0.23 ENST00000334815.6
4-hydroxyphenylpyruvate dioxygenase like
chr20_+_46118277 0.23 ENST00000620709.4
CD40 molecule
chr5_-_135034212 0.23 ENST00000265340.12
paired like homeodomain 1
chr5_-_157575741 0.23 ENST00000517905.1
ADAM metallopeptidase domain 19
chr1_-_42740140 0.22 ENST00000372539.3
ENST00000296387.6
ENST00000539749.5
claudin 19
chr22_-_38088915 0.22 ENST00000428572.1
BAR/IMD domain containing adaptor protein 2 like 2
chr1_-_25906411 0.22 ENST00000455785.7
stathmin 1
chr6_+_54846735 0.22 ENST00000306858.8
family with sequence similarity 83 member B
chr9_+_75890639 0.22 ENST00000545128.5
proprotein convertase subtilisin/kexin type 5
chr19_+_2360238 0.22 ENST00000649857.1
transmembrane serine protease 9
chr12_+_109573757 0.22 ENST00000228510.8
ENST00000539696.5
ENST00000392727.7
mevalonate kinase
chr7_-_27130182 0.22 ENST00000511914.1
homeobox A4
chr12_-_47758828 0.22 ENST00000389212.7
ENST00000449771.7
Rap guanine nucleotide exchange factor 3
chr14_+_74348440 0.22 ENST00000256362.5
vertebrae development associated
chr1_-_153615858 0.22 ENST00000476873.5
S100 calcium binding protein A14
chr15_+_73684373 0.22 ENST00000558689.5
ENST00000560786.6
ENST00000318443.10
ENST00000561213.5
CD276 molecule
chr8_+_38901327 0.21 ENST00000519640.5
ENST00000617275.5
pleckstrin homology domain containing A2
chr11_+_63839086 0.21 ENST00000350490.11
ENST00000402010.8
microtubule affinity regulating kinase 2
chr2_+_85133376 0.21 ENST00000282111.4
transcription factor 7 like 1
chr13_+_97434154 0.21 ENST00000245304.5
RAP2A, member of RAS oncogene family
chr17_-_63700100 0.21 ENST00000578993.5
ENST00000259006.8
ENST00000583211.5
LIM domain containing 2
chr22_-_28679865 0.21 ENST00000397906.6
tetratricopeptide repeat domain 28
chr18_+_58671439 0.21 ENST00000649217.2
MALT1 paracaspase
chr16_-_11256192 0.21 ENST00000644787.1
ENST00000332029.4
suppressor of cytokine signaling 1
chr11_+_63839173 0.21 ENST00000502399.7
ENST00000425897.3
ENST00000513765.7
ENST00000679216.1
microtubule affinity regulating kinase 2
chr21_+_44300038 0.20 ENST00000349048.9
ENST00000628044.1
phosphofructokinase, liver type
chr19_-_19628197 0.20 ENST00000586703.1
ENST00000591042.1
ENST00000407877.8
lysophosphatidic acid receptor 2
chr14_+_90061979 0.20 ENST00000282146.5
potassium two pore domain channel subfamily K member 13
chr9_-_128771909 0.20 ENST00000291900.7
ENST00000414921.5
zyg-11 related cell cycle regulator
chr19_+_41797147 0.20 ENST00000596544.1
CEA cell adhesion molecule 3
chr2_-_240820945 0.19 ENST00000428768.2
ENST00000650053.1
ENST00000650130.1
kinesin family member 1A
chrX_+_49171889 0.19 ENST00000376327.6
proteolipid protein 2
chr17_+_7855055 0.19 ENST00000574668.1
ENST00000301599.7
transmembrane protein 88
chrX_+_21940693 0.19 ENST00000404933.7
ENST00000379404.5
spermine synthase
chr9_-_113299196 0.19 ENST00000441031.3
ring finger protein 183
chr11_-_64246907 0.19 ENST00000309318.8
protein phosphatase 1 regulatory inhibitor subunit 14B
chr7_-_143408848 0.19 ENST00000275815.4
EPH receptor A1
chr16_+_67199509 0.19 ENST00000477898.5
engulfment and cell motility 3
chr3_+_179148341 0.18 ENST00000263967.4
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
chr17_-_8190154 0.18 ENST00000389017.6
BLOC-1 related complex subunit 6
chr9_-_98708856 0.18 ENST00000259455.4
gamma-aminobutyric acid type B receptor subunit 2
chr16_+_68644988 0.18 ENST00000429102.6
cadherin 3
chr16_-_636230 0.18 ENST00000568773.1
methyltransferase like 26
chr17_+_39667964 0.18 ENST00000394246.1
phenylethanolamine N-methyltransferase
chr19_+_35031263 0.18 ENST00000640135.1
ENST00000596348.2
sodium voltage-gated channel beta subunit 1
chr10_+_87863595 0.18 ENST00000371953.8
phosphatase and tensin homolog
chrX_-_19887585 0.18 ENST00000397821.8
SH3 domain containing kinase binding protein 1
chrX_+_132023294 0.18 ENST00000481105.5
ENST00000354719.10
ENST00000394334.7
ENST00000394335.6
serine/threonine kinase 26
chrX_-_153830527 0.18 ENST00000393758.7
ENST00000544474.5
PDZ domain containing 4
chr13_+_96090098 0.18 ENST00000376705.4
heparan sulfate 6-O-sulfotransferase 3
chr1_-_97921042 0.18 ENST00000306031.5
dihydropyrimidine dehydrogenase
chr10_-_97633485 0.18 ENST00000370635.3
ENST00000478953.1
ENST00000307450.11
MORN repeat containing 4
chr16_+_28824116 0.18 ENST00000568266.5
ataxin 2 like
chr19_+_35704540 0.18 ENST00000392197.7
ENST00000426659.6
zinc finger and BTB domain containing 32

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.4 1.2 GO:1990927 short-term synaptic potentiation(GO:1990926) calcium ion regulated lysosome exocytosis(GO:1990927)
0.4 1.1 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.2 1.0 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.2 0.7 GO:0009720 detection of hormone stimulus(GO:0009720)
0.2 0.5 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.2 0.6 GO:1904692 positive regulation of type B pancreatic cell proliferation(GO:1904692)
0.2 0.9 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.2 0.7 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.2 0.5 GO:0036451 cap mRNA methylation(GO:0036451)
0.1 0.4 GO:0051463 negative regulation of cortisol secretion(GO:0051463)
0.1 1.0 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 0.4 GO:0048817 negative regulation of transforming growth factor beta2 production(GO:0032912) negative regulation of hair follicle maturation(GO:0048817) regulation of melanosome transport(GO:1902908)
0.1 0.3 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.1 0.6 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1 1.4 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.1 0.3 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.3 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.8 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 0.3 GO:0010193 response to ozone(GO:0010193)
0.1 0.3 GO:0051586 glial cell-derived neurotrophic factor secretion(GO:0044467) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
0.1 0.2 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.3 GO:0035634 response to stilbenoid(GO:0035634)
0.1 0.3 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1 0.3 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.4 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.3 GO:0006258 UDP-glucose catabolic process(GO:0006258) negative regulation of type B pancreatic cell development(GO:2000077)
0.1 0.3 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.1 0.3 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 0.4 GO:0061143 alveolar primary septum development(GO:0061143)
0.1 0.2 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.1 0.4 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.1 0.7 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.2 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.3 GO:0036018 response to cobalamin(GO:0033590) cellular response to erythropoietin(GO:0036018)
0.0 0.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 1.5 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.0 GO:0035106 operant conditioning(GO:0035106)
0.0 0.5 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 1.3 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.3 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 1.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.3 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.3 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.2 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.4 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.7 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.3 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.2 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.2 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.0 0.1 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.4 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.1 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.2 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.0 0.1 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.2 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.0 0.6 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.1 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.0 0.4 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 4.6 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.2 GO:2000630 positive regulation of miRNA metabolic process(GO:2000630)
0.0 0.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.2 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.3 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.0 GO:0003192 mitral valve formation(GO:0003192)
0.0 0.4 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0035854 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.0 0.1 GO:0097374 proprioception(GO:0019230) sensory neuron axon guidance(GO:0097374)
0.0 0.4 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.2 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 1.0 GO:0097503 sialylation(GO:0097503)
0.0 0.1 GO:0021634 optic nerve formation(GO:0021634) optic chiasma development(GO:0061360) regulation of optic nerve formation(GO:2000595) positive regulation of optic nerve formation(GO:2000597)
0.0 0.2 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822)
0.0 0.3 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.1 GO:0021593 rhombomere morphogenesis(GO:0021593) rhombomere 3 morphogenesis(GO:0021658)
0.0 0.1 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.2 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.2 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.3 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.2 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.0 0.3 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.2 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.3 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.3 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:1902075 cellular response to salt(GO:1902075)
0.0 0.2 GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.7 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.1 GO:0010755 regulation of plasminogen activation(GO:0010755) negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0002125 maternal aggressive behavior(GO:0002125)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.3 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.2 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.0 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.0 0.0 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.3 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.1 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.5 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.1 GO:1904526 regulation of microtubule binding(GO:1904526)
0.0 0.1 GO:0002934 desmosome organization(GO:0002934)
0.0 0.2 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.4 GO:0051412 response to corticosterone(GO:0051412)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.8 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:0003360 brainstem development(GO:0003360)
0.0 0.1 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.6 GO:0071622 regulation of granulocyte chemotaxis(GO:0071622)
0.0 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.2 GO:0032196 transposition(GO:0032196)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.1 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.7 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.3 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.9 GO:0006626 protein targeting to mitochondrion(GO:0006626)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0097513 myosin II filament(GO:0097513)
0.1 1.2 GO:0032009 early phagosome(GO:0032009)
0.1 0.3 GO:0097444 spine apparatus(GO:0097444)
0.1 0.4 GO:1990032 parallel fiber(GO:1990032)
0.1 0.2 GO:0036284 tubulobulbar complex(GO:0036284)
0.1 0.2 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 5.0 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.2 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0032449 CBM complex(GO:0032449)
0.0 0.4 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 1.2 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.4 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.3 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.6 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 1.6 GO:1903293 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.0 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0005861 troponin complex(GO:0005861)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0070404 NADH binding(GO:0070404)
0.2 0.7 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.2 0.9 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.2 0.7 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.2 0.7 GO:0004773 steryl-sulfatase activity(GO:0004773)
0.2 0.5 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.2 0.6 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 2.4 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.1 0.3 GO:0047325 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.1 1.0 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.1 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.1 0.3 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.1 0.2 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1 0.8 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.2 GO:0000994 RNA polymerase III core binding(GO:0000994)
0.1 0.2 GO:0030350 iron-responsive element binding(GO:0030350)
0.1 0.3 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.1 0.3 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.1 0.3 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.4 GO:0070004 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.1 0.9 GO:0008199 ferric iron binding(GO:0008199)
0.1 0.2 GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 0.2 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.3 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 1.5 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.2 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.0 0.3 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.2 GO:0004803 transposase activity(GO:0004803)
0.0 0.2 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.4 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0000248 C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.2 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.3 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.3 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.1 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.1 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.6 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.8 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.6 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0035240 dopamine binding(GO:0035240)
0.0 1.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.0 GO:0052858 peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.3 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.4 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.3 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.7 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0016015 morphogen activity(GO:0016015)
0.0 1.8 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:1902444 riboflavin binding(GO:1902444)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.6 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.2 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.5 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 2.6 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 1.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.9 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.6 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 1.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.9 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.6 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.4 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters