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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for TFAP2E

Z-value: 0.43

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Transcription factors associated with TFAP2E

Gene Symbol Gene ID Gene Info
TFAP2E
ENSG00000116819.9 TFAP2E

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFAP2Ehg38_v1_chr1_+_35573308_355733190.402.9e-02Click!

Activity profile of TFAP2E motif

Sorted Z-values of TFAP2E motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP2E

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr19_-_43465596 1.18 ENST00000244333.4
LYPD3
LY6/PLAUR domain containing 3
chr2_+_74834113 0.96 ENST00000290573.7
HK2
hexokinase 2
chr11_+_47215032 0.82 ENST00000622090.4
ENST00000378600.7
ENST00000378603.7
DDB2
damage specific DNA binding protein 2
chr20_+_6767678 0.82 ENST00000378827.5
BMP2
bone morphogenetic protein 2
chr17_-_41612757 0.71 ENST00000301653.9
ENST00000593067.1
KRT16
keratin 16
chr11_-_61295289 0.71 ENST00000335613.10
VWCE
von Willebrand factor C and EGF domains
chr9_+_4985227 0.70 ENST00000381652.4
JAK2
Janus kinase 2
chr15_-_52528870 0.69 ENST00000399233.7
ENST00000356338.10
MYO5A
myosin VA
chr7_-_45088888 0.68 ENST00000490531.3
NACAD
NAC alpha domain containing
chr10_-_131981948 0.68 ENST00000633835.1
BNIP3
BCL2 interacting protein 3
chr4_+_2829797 0.68 ENST00000513069.1
SH3BP2
SH3 domain binding protein 2
chr3_+_50155305 0.60 ENST00000002829.8
ENST00000426511.5
SEMA3F
semaphorin 3F
chr10_-_77637902 0.60 ENST00000286627.10
ENST00000639486.1
ENST00000640523.1
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
chr11_+_118607579 0.59 ENST00000530708.4
PHLDB1
pleckstrin homology like domain family B member 1
chr3_-_48088800 0.52 ENST00000423088.5
MAP4
microtubule associated protein 4
chr3_-_48088824 0.52 ENST00000439356.2
ENST00000395734.7
ENST00000426837.6
MAP4
microtubule associated protein 4
chr10_-_77638369 0.50 ENST00000372443.6
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
chr1_-_40862354 0.49 ENST00000372638.4
CITED4
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4
chr17_+_38428456 0.47 ENST00000622683.5
ENST00000620417.4
ARHGAP23
Rho GTPase activating protein 23
chr7_-_23014074 0.47 ENST00000409763.1
ENST00000679826.1
ENST00000409923.5
ENST00000681766.1
FAM126A
family with sequence similarity 126 member A
chr1_-_43453902 0.45 ENST00000372430.9
ENST00000372432.5
ENST00000583037.5
HYI
hydroxypyruvate isomerase (putative)
chr6_-_87702221 0.45 ENST00000257787.6
AKIRIN2
akirin 2
chr11_+_57805541 0.44 ENST00000683201.1
ENST00000683769.1
CTNND1
catenin delta 1
chr7_-_140924900 0.44 ENST00000646891.1
ENST00000644969.2
BRAF
B-Raf proto-oncogene, serine/threonine kinase
chr12_+_53050179 0.43 ENST00000546602.5
ENST00000552570.5
ENST00000549700.5
TNS2
tensin 2
chr1_-_43453792 0.42 ENST00000372434.5
ENST00000486909.1
HYI
hydroxypyruvate isomerase (putative)
chr22_+_39994926 0.42 ENST00000333407.11
FAM83F
family with sequence similarity 83 member F
chr1_-_93847150 0.42 ENST00000370244.5
BCAR3
BCAR3 adaptor protein, NSP family member
chr1_-_43453716 0.41 ENST00000372433.5
HYI
hydroxypyruvate isomerase (putative)
chr7_-_23014099 0.41 ENST00000432176.7
ENST00000440481.6
FAM126A
family with sequence similarity 126 member A
chr11_-_66289007 0.41 ENST00000431556.6
ENST00000528575.1
YIF1A
Yip1 interacting factor homolog A, membrane trafficking protein
chr7_-_140924699 0.41 ENST00000288602.11
ENST00000469930.2
ENST00000496384.7
BRAF
B-Raf proto-oncogene, serine/threonine kinase
chrX_+_49171889 0.41 ENST00000376327.6
PLP2
proteolipid protein 2
chr19_-_38773432 0.40 ENST00000599035.1
ENST00000378626.5
LGALS7
galectin 7
chr19_+_54449180 0.40 ENST00000439657.5
ENST00000326764.10
ENST00000376514.6
ENST00000436479.1
LENG8
leukocyte receptor cluster member 8
chr5_-_151924846 0.38 ENST00000274576.9
GLRA1
glycine receptor alpha 1
chr6_+_42564060 0.37 ENST00000372903.6
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr2_-_240892007 0.37 ENST00000402775.6
ENST00000307486.12
MAB21L4
mab-21 like 4
chr1_-_43368039 0.37 ENST00000413844.3
ELOVL1
ELOVL fatty acid elongase 1
chr8_-_126557691 0.36 ENST00000652209.1
LRATD2
LRAT domain containing 2
chr5_-_151924824 0.36 ENST00000455880.2
GLRA1
glycine receptor alpha 1
chr11_+_118607598 0.36 ENST00000600882.6
ENST00000356063.9
PHLDB1
pleckstrin homology like domain family B member 1
chr4_-_152679984 0.36 ENST00000304385.8
ENST00000504064.1
TMEM154
transmembrane protein 154
chr17_+_39668447 0.35 ENST00000269582.3
ENST00000581428.1
PNMT
phenylethanolamine N-methyltransferase
chr22_-_38700920 0.35 ENST00000456626.1
ENST00000412832.1
ENST00000683374.1
JOSD1
Josephin domain containing 1
chr3_+_4493340 0.35 ENST00000357086.10
ENST00000354582.12
ENST00000649015.2
ENST00000467056.6
ITPR1
inositol 1,4,5-trisphosphate receptor type 1
chr3_+_4493442 0.35 ENST00000456211.8
ENST00000443694.5
ENST00000648266.1
ITPR1
inositol 1,4,5-trisphosphate receptor type 1
chr17_+_39667964 0.35 ENST00000394246.1
PNMT
phenylethanolamine N-methyltransferase
chr14_+_24368020 0.35 ENST00000554050.5
ENST00000554903.1
ENST00000250373.9
ENST00000554779.1
ENST00000553708.5
NFATC4
nuclear factor of activated T cells 4
chr8_+_25184668 0.33 ENST00000276440.12
ENST00000410074.5
DOCK5
dedicator of cytokinesis 5
chr3_+_4493471 0.33 ENST00000544951.6
ENST00000650294.1
ITPR1
inositol 1,4,5-trisphosphate receptor type 1
chr22_-_38700655 0.31 ENST00000216039.9
JOSD1
Josephin domain containing 1
chr17_-_35089212 0.31 ENST00000584655.5
ENST00000447669.6
ENST00000315249.11
RFFL
ring finger and FYVE like domain containing E3 ubiquitin protein ligase
chr2_+_186694076 0.31 ENST00000612606.1
FAM171B
family with sequence similarity 171 member B
chr1_-_85048437 0.31 ENST00000341115.8
ENST00000370587.5
ENST00000370589.7
MCOLN3
mucolipin TRP cation channel 3
chr1_-_11805924 0.30 ENST00000418034.1
MTHFR
methylenetetrahydrofolate reductase
chr4_-_81471855 0.29 ENST00000436139.6
ENST00000613784.1
RASGEF1B
RasGEF domain family member 1B
chr17_+_3723889 0.29 ENST00000325418.5
HASPIN
histone H3 associated protein kinase
chr9_+_133636355 0.29 ENST00000393056.8
DBH
dopamine beta-hydroxylase
chr14_+_103385450 0.28 ENST00000416682.6
MARK3
microtubule affinity regulating kinase 3
chr16_+_89948697 0.28 ENST00000567999.5
ENST00000610455.4
ENST00000617948.4
ENST00000566079.5
ENST00000566820.5
ENST00000562578.5
ENST00000563594.6
ENST00000561741.5
ENST00000268676.11
ENST00000562986.5
ENST00000569453.5
ENST00000567884.5
ENST00000569061.5
ENST00000418391.6
ENST00000561959.5
ENST00000567874.5
ENST00000570182.5
ENST00000563795.1
DEF8
differentially expressed in FDCP 8 homolog
chr1_-_11805977 0.27 ENST00000376486.3
MTHFR
methylenetetrahydrofolate reductase
chr19_+_4969105 0.27 ENST00000611640.4
ENST00000159111.9
ENST00000588337.5
ENST00000381759.8
KDM4B
lysine demethylase 4B
chr19_+_48954850 0.27 ENST00000345358.12
ENST00000539787.2
ENST00000415969.6
ENST00000354470.7
ENST00000506183.5
ENST00000391871.4
ENST00000293288.12
BAX
BCL2 associated X, apoptosis regulator
chrX_-_124963768 0.27 ENST00000371130.7
ENST00000422452.2
TENM1
teneurin transmembrane protein 1
chr2_+_186694007 0.26 ENST00000304698.10
FAM171B
family with sequence similarity 171 member B
chrX_+_49171918 0.26 ENST00000376322.7
PLP2
proteolipid protein 2
chr4_+_153466324 0.26 ENST00000409663.7
ENST00000409959.8
TMEM131L
transmembrane 131 like
chr13_-_26760741 0.25 ENST00000405846.5
GPR12
G protein-coupled receptor 12
chr11_-_65857543 0.25 ENST00000534784.1
CFL1
cofilin 1
chrX_+_129738942 0.25 ENST00000371106.4
XPNPEP2
X-prolyl aminopeptidase 2
chrX_+_132023294 0.24 ENST00000481105.5
ENST00000354719.10
ENST00000394334.7
ENST00000394335.6
STK26
serine/threonine kinase 26
chr1_+_966466 0.24 ENST00000379410.8
ENST00000379407.7
ENST00000379409.6
PLEKHN1
pleckstrin homology domain containing N1
chr1_-_11805949 0.24 ENST00000376590.9
MTHFR
methylenetetrahydrofolate reductase
chr1_+_213989691 0.22 ENST00000607425.1
PROX1
prospero homeobox 1
chr9_+_135714425 0.22 ENST00000473941.5
ENST00000486577.6
KCNT1
potassium sodium-activated channel subfamily T member 1
chr6_+_7107597 0.20 ENST00000379933.7
ENST00000491191.5
ENST00000471433.5
RREB1
ras responsive element binding protein 1
chr11_-_65856944 0.19 ENST00000524553.5
CFL1
cofilin 1
chr11_-_35419542 0.19 ENST00000643305.1
ENST00000644351.1
ENST00000278379.9
ENST00000644779.1
SLC1A2
solute carrier family 1 member 2
chr6_+_42563981 0.18 ENST00000372899.6
ENST00000372901.2
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr17_-_76726753 0.18 ENST00000617192.4
JMJD6
jumonji domain containing 6, arginine demethylase and lysine hydroxylase
chr6_+_7107941 0.18 ENST00000379938.7
ENST00000467782.5
ENST00000334984.10
ENST00000349384.10
RREB1
ras responsive element binding protein 1
chr14_+_103385374 0.17 ENST00000678179.1
ENST00000676938.1
ENST00000678619.1
ENST00000440884.7
ENST00000560417.6
ENST00000679330.1
ENST00000556744.2
ENST00000676897.1
ENST00000677560.1
ENST00000561314.6
ENST00000677829.1
ENST00000677133.1
ENST00000676645.1
ENST00000678175.1
ENST00000429436.7
ENST00000677360.1
ENST00000678237.1
ENST00000677347.1
ENST00000677432.1
MARK3
microtubule affinity regulating kinase 3
chr11_-_65857007 0.17 ENST00000527344.5
CFL1
cofilin 1
chr14_+_103385506 0.17 ENST00000303622.13
MARK3
microtubule affinity regulating kinase 3
chr3_-_49411917 0.15 ENST00000454011.7
ENST00000445425.6
ENST00000422781.6
ENST00000418115.6
ENST00000678921.2
ENST00000676712.2
RHOA
ras homolog family member A
chr2_-_37324826 0.15 ENST00000234179.8
PRKD3
protein kinase D3
chr4_+_6909444 0.15 ENST00000448507.5
TBC1D14
TBC1 domain family member 14
chr9_-_21077938 0.14 ENST00000380232.4
IFNB1
interferon beta 1
chr5_+_177133005 0.14 ENST00000510954.5
ENST00000354179.8
NSD1
nuclear receptor binding SET domain protein 1
chr5_+_134648772 0.14 ENST00000398844.7
ENST00000322887.8
SEC24A
SEC24 homolog A, COPII coat complex component
chr1_+_3069160 0.13 ENST00000511072.5
PRDM16
PR/SET domain 16
chr19_+_35704540 0.13 ENST00000392197.7
ENST00000426659.6
ZBTB32
zinc finger and BTB domain containing 32
chr4_-_81471898 0.12 ENST00000335927.11
ENST00000264400.7
ENST00000504863.1
RASGEF1B
RasGEF domain family member 1B
chr1_-_224434750 0.12 ENST00000414423.9
ENST00000678917.1
ENST00000678555.1
ENST00000678307.1
WDR26
WD repeat domain 26
chr9_+_35605277 0.12 ENST00000620767.4
TESK1
testis associated actin remodelling kinase 1
chr10_+_100735390 0.12 ENST00000679374.1
PAX2
paired box 2
chr9_+_35605234 0.12 ENST00000336395.6
TESK1
testis associated actin remodelling kinase 1
chr11_-_62612521 0.12 ENST00000278845.8
ENST00000529309.5
EML3
EMAP like 3
chr12_-_14567714 0.12 ENST00000240617.10
PLBD1
phospholipase B domain containing 1
chr2_-_74529670 0.11 ENST00000377526.4
AUP1
AUP1 lipid droplet regulating VLDL assembly factor
chr11_+_116829898 0.11 ENST00000227667.8
ENST00000375345.3
APOC3
apolipoprotein C3
chr19_+_50432885 0.11 ENST00000357701.6
MYBPC2
myosin binding protein C2
chr20_-_25390776 0.11 ENST00000376542.8
ENST00000339157.10
ABHD12
abhydrolase domain containing 12, lysophospholipase
chr2_+_38666059 0.10 ENST00000272252.10
ENST00000410063.5
GALM
galactose mutarotase
chr17_-_38799442 0.10 ENST00000619039.5
PIP4K2B
phosphatidylinositol-5-phosphate 4-kinase type 2 beta
chr6_-_29633171 0.10 ENST00000377034.9
GABBR1
gamma-aminobutyric acid type B receptor subunit 1
chr2_+_6917404 0.10 ENST00000320892.11
RNF144A
ring finger protein 144A
chr6_-_29633056 0.10 ENST00000377016.8
GABBR1
gamma-aminobutyric acid type B receptor subunit 1
chr3_+_49554436 0.09 ENST00000296452.5
BSN
bassoon presynaptic cytomatrix protein
chr12_-_56630293 0.08 ENST00000546695.5
ENST00000549884.6
BAZ2A
bromodomain adjacent to zinc finger domain 2A
chr1_-_201377652 0.08 ENST00000455702.6
ENST00000367320.6
ENST00000421663.6
ENST00000412633.3
ENST00000367318.10
ENST00000422165.6
ENST00000656932.1
ENST00000438742.6
ENST00000367322.6
ENST00000458432.6
ENST00000509001.5
ENST00000660295.1
TNNT2
troponin T2, cardiac type
chr11_+_82901698 0.08 ENST00000524921.5
ENST00000528759.5
ENST00000525361.5
ENST00000532764.5
ENST00000532589.5
ENST00000533655.6
ENST00000525388.5
DDIAS
DNA damage induced apoptosis suppressor
chr15_+_84817346 0.08 ENST00000258888.6
ALPK3
alpha kinase 3
chr11_-_66289125 0.07 ENST00000471387.6
ENST00000376901.9
ENST00000359461.10
YIF1A
Yip1 interacting factor homolog A, membrane trafficking protein
chr4_+_6909775 0.07 ENST00000409757.9
TBC1D14
TBC1 domain family member 14
chr1_-_113812448 0.07 ENST00000612242.4
ENST00000261441.9
RSBN1
round spermatid basic protein 1
chr13_-_75482151 0.06 ENST00000377636.8
TBC1D4
TBC1 domain family member 4
chr22_-_45977154 0.06 ENST00000339464.9
WNT7B
Wnt family member 7B
chr19_+_38304105 0.06 ENST00000588605.5
ENST00000301246.10
C19orf33
chromosome 19 open reading frame 33
chr20_+_24469623 0.06 ENST00000376862.4
SYNDIG1
synapse differentiation inducing 1
chr1_-_113812254 0.06 ENST00000616024.4
ENST00000615321.1
RSBN1
round spermatid basic protein 1
chr10_-_124092390 0.06 ENST00000628426.1
CHST15
carbohydrate sulfotransferase 15
chr3_-_55487295 0.06 ENST00000264634.9
WNT5A
Wnt family member 5A
chr10_-_96513911 0.06 ENST00000357947.4
TLL2
tolloid like 2
chr19_+_3572927 0.05 ENST00000333651.11
ENST00000417382.5
HMG20B
high mobility group 20B
chr1_-_11691608 0.05 ENST00000376667.7
MAD2L2
mitotic arrest deficient 2 like 2
chr11_-_35419899 0.05 ENST00000646847.1
ENST00000449068.2
ENST00000643401.1
ENST00000645966.1
ENST00000647104.1
SLC1A2
solute carrier family 1 member 2
chr1_+_22563460 0.04 ENST00000166244.8
ENST00000374644.8
EPHA8
EPH receptor A8
chr2_+_218859794 0.04 ENST00000233948.4
WNT6
Wnt family member 6
chr7_+_151085858 0.04 ENST00000463381.5
AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr11_-_35420017 0.04 ENST00000643000.1
ENST00000646099.1
ENST00000647372.1
ENST00000642578.1
SLC1A2
solute carrier family 1 member 2
chr13_-_75482114 0.04 ENST00000377625.6
ENST00000431480.6
TBC1D4
TBC1 domain family member 4
chr7_+_130070518 0.04 ENST00000335420.10
ENST00000463413.1
KLHDC10
kelch domain containing 10
chr1_-_11691646 0.04 ENST00000235310.7
MAD2L2
mitotic arrest deficient 2 like 2
chr17_+_30831944 0.03 ENST00000321990.5
ATAD5
ATPase family AAA domain containing 5
chr19_+_13118235 0.02 ENST00000292431.5
NACC1
nucleus accumbens associated 1
chr4_-_100517991 0.02 ENST00000511970.5
ENST00000502569.1
ENST00000305864.7
ENST00000296420.9
EMCN
endomucin
chr19_+_3572777 0.02 ENST00000416526.5
HMG20B
high mobility group 20B
chr11_-_27506751 0.01 ENST00000278193.7
ENST00000524596.1
LIN7C
lin-7 homolog C, crumbs cell polarity complex component
chr19_-_10503186 0.01 ENST00000592055.2
ENST00000171111.10
KEAP1
kelch like ECH associated protein 1
chr19_+_3572971 0.01 ENST00000453933.5
ENST00000262949.7
HMG20B
high mobility group 20B
chr4_+_41990496 0.01 ENST00000264451.12
SLC30A9
solute carrier family 30 member 9
chrX_+_106802660 0.00 ENST00000357242.10
ENST00000310452.6
ENST00000481617.6
ENST00000276175.7
TBC1D8B
TBC1 domain family member 8B
chr14_-_60486021 0.00 ENST00000555476.5
ENST00000321731.8
C14orf39
chromosome 14 open reading frame 39
chr1_+_3069195 0.00 ENST00000378391.6
ENST00000270722.10
ENST00000514189.5
PRDM16
PR/SET domain 16

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040) corticotropin hormone secreting cell differentiation(GO:0060128)
0.2 0.7 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.2 0.7 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.2 1.0 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.2 1.0 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.8 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.6 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.7 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.1 0.8 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 0.4 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.7 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 1.0 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.7 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.1 0.3 GO:1902512 B cell selection(GO:0002339) positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.1 0.6 GO:0051511 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.1 0.3 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 0.6 GO:0035290 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.1 1.1 GO:0034465 response to carbon monoxide(GO:0034465)
0.1 0.2 GO:0043049 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.3 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.3 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.2 GO:0070079 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine(GO:0018395) histone arginine demethylation(GO:0070077) histone H3-R2 demethylation(GO:0070078) histone H4-R3 demethylation(GO:0070079)
0.1 0.6 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.8 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.1 1.0 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.3 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 0.2 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 0.1 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.0 0.6 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.4 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.1 GO:0021634 optic nerve formation(GO:0021634) optic chiasma development(GO:0061360) regulation of optic nerve formation(GO:2000595) positive regulation of optic nerve formation(GO:2000597)
0.0 0.3 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.1 GO:0060621 regulation of high-density lipoprotein particle clearance(GO:0010982) negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.0 0.1 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.1 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.0 0.1 GO:0060775 cardiac right atrium morphogenesis(GO:0003213) mediolateral intercalation(GO:0060031) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346) regulation of cell proliferation in midbrain(GO:1904933)
0.0 0.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.0 0.1 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.0 0.1 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.4 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 1.4 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.4 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.4 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 1.0 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.8 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.0 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.7 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.4 GO:0005915 zonula adherens(GO:0005915)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 1.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 1.6 GO:0005901 caveola(GO:0005901)
0.0 0.6 GO:0031258 lamellipodium membrane(GO:0031258)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0008903 hydroxypyruvate isomerase activity(GO:0008903)
0.1 0.7 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.8 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 1.0 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 1.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 1.0 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.7 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 0.6 GO:0070728 leucine binding(GO:0070728)
0.1 0.8 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.2 GO:0033749 histone demethylase activity (H3-R2 specific)(GO:0033746) histone demethylase activity (H4-R3 specific)(GO:0033749)
0.0 0.3 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.4 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.6 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.8 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 1.2 GO:0043236 laminin binding(GO:0043236)
0.0 0.2 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.7 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.1 GO:0046975 histone methyltransferase activity (H4-K20 specific)(GO:0042799) histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.8 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.0 ST GAQ PATHWAY G alpha q Pathway
0.0 0.6 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.8 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.8 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.8 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.0 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.7 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs