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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for TFAP4_MSC

Z-value: 0.76

Motif logo

Transcription factors associated with TFAP4_MSC

Gene Symbol Gene ID Gene Info
ENSG00000090447.12 TFAP4
ENSG00000178860.9 MSC

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MSChg38_v1_chr8_-_71844402_71844429-0.261.7e-01Click!
TFAP4hg38_v1_chr16_-_4273014_42730650.058.0e-01Click!

Activity profile of TFAP4_MSC motif

Sorted Z-values of TFAP4_MSC motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP4_MSC

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_+_3799424 4.46 ENST00000319331.4
leucine rich repeat neuronal 1
chr16_-_21278282 3.45 ENST00000572914.2
crystallin mu
chr16_-_67393486 2.83 ENST00000562206.1
ENST00000393957.7
ENST00000290942.9
tubulin polymerization promoting protein family member 3
chr6_+_17281341 2.58 ENST00000379052.10
RNA binding motif protein 24
chr2_+_85753984 2.35 ENST00000306279.4
atonal bHLH transcription factor 8
chr8_-_71362054 2.34 ENST00000340726.8
EYA transcriptional coactivator and phosphatase 1
chr8_-_71361860 2.25 ENST00000303824.11
ENST00000645451.1
EYA transcriptional coactivator and phosphatase 1
chr6_-_24910695 2.09 ENST00000643623.1
ENST00000538035.6
ENST00000647136.1
RHO family interacting cell polarization regulator 2
chr15_-_40108861 2.07 ENST00000354670.9
ENST00000559701.5
ENST00000557870.1
ENST00000558774.5
Bcl2 modifying factor
chr6_-_39229465 1.92 ENST00000359534.4
potassium two pore domain channel subfamily K member 5
chr11_+_45896541 1.67 ENST00000395629.2
mitogen-activated protein kinase 8 interacting protein 1
chr8_-_109648767 1.66 ENST00000424158.6
syntabulin
chr5_+_176810552 1.63 ENST00000329542.9
unc-5 netrin receptor A
chr4_+_74933108 1.58 ENST00000307428.7
prostate androgen-regulated mucin-like protein 1
chr4_+_74933095 1.58 ENST00000513238.5
prostate androgen-regulated mucin-like protein 1
chr8_-_109648825 1.46 ENST00000533895.5
ENST00000446070.6
ENST00000528331.5
ENST00000526302.5
ENST00000408908.6
ENST00000433638.1
ENST00000524720.5
syntabulin
chr6_-_24911029 1.38 ENST00000259698.9
ENST00000644621.1
ENST00000644411.1
RHO family interacting cell polarization regulator 2
chr22_-_35617321 1.32 ENST00000397326.7
ENST00000442617.1
myoglobin
chr5_+_51383394 1.24 ENST00000230658.12
ISL LIM homeobox 1
chr22_+_30607145 1.21 ENST00000405742.7
transcobalamin 2
chr7_-_130441136 1.18 ENST00000675596.1
ENST00000676312.1
centrosomal protein 41
chr22_+_30607167 1.17 ENST00000215838.8
transcobalamin 2
chr22_+_30607072 1.15 ENST00000450638.5
transcobalamin 2
chr12_+_48904116 1.15 ENST00000552942.5
ENST00000320516.5
coiled-coil domain containing 65
chr1_-_150697128 1.11 ENST00000427665.1
ENST00000271732.8
golgi phosphoprotein 3 like
chr4_+_73836667 1.05 ENST00000226317.10
C-X-C motif chemokine ligand 6
chr8_+_80486209 1.04 ENST00000426744.5
ENST00000455036.8
zinc finger and BTB domain containing 10
chr6_+_52423680 1.02 ENST00000538167.2
EF-hand domain containing 1
chr1_+_212565334 1.01 ENST00000366981.8
ENST00000366987.6
activating transcription factor 3
chr9_-_86947496 0.99 ENST00000298743.9
growth arrest specific 1
chr1_-_216723410 0.97 ENST00000469486.5
ENST00000481543.1
ENST00000408911.8
estrogen related receptor gamma
chr20_-_40689228 0.97 ENST00000373313.3
MAF bZIP transcription factor B
chr1_-_216723437 0.96 ENST00000459955.5
ENST00000366937.5
ENST00000391890.7
estrogen related receptor gamma
chr22_+_30607203 0.95 ENST00000407817.3
transcobalamin 2
chr10_+_92834594 0.91 ENST00000371552.8
exocyst complex component 6
chr3_+_49020443 0.88 ENST00000326912.8
NADH:ubiquinone oxidoreductase complex assembly factor 3
chr14_-_75981986 0.88 ENST00000238682.8
transforming growth factor beta 3
chr1_-_183653307 0.88 ENST00000308641.6
apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4
chr22_+_35381086 0.88 ENST00000216117.9
ENST00000677931.1
ENST00000679074.1
heme oxygenase 1
chr10_-_13099652 0.87 ENST00000378839.1
coiled-coil domain containing 3
chrY_+_12662344 0.85 ENST00000651177.1
ubiquitin specific peptidase 9 Y-linked
chr11_-_85719160 0.83 ENST00000389958.7
ENST00000527794.5
synaptotagmin like 2
chr8_+_80485641 0.83 ENST00000430430.5
zinc finger and BTB domain containing 10
chr17_+_70075215 0.83 ENST00000283936.5
ENST00000615244.4
ENST00000392671.6
potassium inwardly rectifying channel subfamily J member 16
chr7_-_29990113 0.83 ENST00000426154.5
ENST00000421434.5
ENST00000434476.6
secernin 1
chr17_+_70075317 0.82 ENST00000589377.1
potassium inwardly rectifying channel subfamily J member 16
chr3_+_49021071 0.82 ENST00000395458.6
NADH:ubiquinone oxidoreductase complex assembly factor 3
chr17_+_5078450 0.82 ENST00000318833.4
ZFP3 zinc finger protein
chr7_-_29989774 0.81 ENST00000242059.10
secernin 1
chr11_-_85719111 0.80 ENST00000529581.5
ENST00000533577.1
synaptotagmin like 2
chr4_+_85778681 0.79 ENST00000395183.6
Rho GTPase activating protein 24
chr2_+_94871419 0.79 ENST00000295201.5
tektin 4
chr12_+_66189208 0.77 ENST00000261233.9
interleukin 1 receptor associated kinase 3
chr3_-_193554885 0.74 ENST00000342695.9
ATPase 13A4
chr1_+_109539865 0.73 ENST00000618721.4
ENST00000527748.5
ENST00000616874.1
G protein-coupled receptor 61
chr12_+_104064520 0.73 ENST00000229330.9
host cell factor C2
chr12_+_56079843 0.70 ENST00000549282.5
ENST00000549061.5
ENST00000683059.1
erb-b2 receptor tyrosine kinase 3
chr2_+_232697299 0.69 ENST00000476995.5
ENST00000427233.5
ENST00000629305.2
ENST00000428883.5
ENST00000456491.5
ENST00000409480.5
ENST00000492910.5
ENST00000464402.5
ENST00000490612.5
ENST00000475359.6
ENST00000421433.5
ENST00000425040.5
ENST00000430720.5
ENST00000409547.5
ENST00000373563.9
ENST00000423659.5
ENST00000409196.7
ENST00000488734.5
ENST00000409451.7
ENST00000429187.5
ENST00000440945.5
GRB10 interacting GYF protein 2
chr3_-_183555696 0.68 ENST00000341319.8
kelch like family member 6
chr11_+_7576408 0.65 ENST00000533792.5
PPFIA binding protein 2
chr12_+_121712740 0.63 ENST00000449592.7
transmembrane protein 120B
chr1_-_33182030 0.62 ENST00000291416.10
tripartite motif containing 62
chr12_+_48904105 0.61 ENST00000266984.9
coiled-coil domain containing 65
chr19_+_18097763 0.59 ENST00000262811.10
microtubule associated serine/threonine kinase 3
chr6_+_46793379 0.58 ENST00000230588.9
ENST00000611727.2
meprin A subunit alpha
chr10_+_94089067 0.58 ENST00000371375.1
ENST00000675218.1
phospholipase C epsilon 1
chr2_+_229922482 0.58 ENST00000283946.8
ENST00000409992.1
F-box protein 36
chr10_+_94089034 0.57 ENST00000676102.1
ENST00000371385.8
phospholipase C epsilon 1
chr3_-_193554952 0.57 ENST00000392443.7
ATPase 13A4
chr3_-_64225436 0.56 ENST00000638394.2
prickle planar cell polarity protein 2
chr7_+_129144691 0.55 ENST00000486685.3
tetraspanin 33
chr4_-_82561972 0.55 ENST00000454948.3
ENST00000449862.7
transmembrane protein 150C
chr1_+_222928415 0.54 ENST00000284476.7
dispatched RND transporter family member 1
chr12_-_53727476 0.53 ENST00000549784.5
ENST00000262059.8
calcium binding and coiled-coil domain 1
chr15_+_43517590 0.53 ENST00000300231.6
microtubule associated protein 1A
chr12_+_71839707 0.53 ENST00000482439.6
ENST00000550746.5
ENST00000491063.5
ENST00000319106.12
ENST00000485960.7
TBC1 domain family member 15
chr1_-_24415035 0.53 ENST00000374409.5
sperm tail PG-rich repeat containing 1
chr2_-_177552781 0.53 ENST00000408939.4
tetratricopeptide repeat domain 30B
chr7_+_117020191 0.52 ENST00000434836.5
ENST00000393443.5
ENST00000465133.5
ENST00000477742.5
ENST00000393444.7
ENST00000393447.8
suppression of tumorigenicity 7
chr10_+_113125536 0.52 ENST00000349937.7
transcription factor 7 like 2
chr15_+_67254776 0.52 ENST00000335894.9
ENST00000512104.5
IQ motif containing H
chr11_-_1608463 0.51 ENST00000399685.1
keratin associated protein 5-3
chr12_-_53727428 0.51 ENST00000548263.5
ENST00000430117.6
ENST00000549173.5
ENST00000550804.6
ENST00000551900.5
ENST00000546619.5
ENST00000548177.5
ENST00000549349.5
calcium binding and coiled-coil domain 1
chr11_-_62707581 0.50 ENST00000684475.1
ENST00000683296.1
ENST00000684067.1
ENST00000682223.1
BSCL2 lipid droplet biogenesis associated, seipin
chr8_+_97775775 0.50 ENST00000521545.7
lysosomal protein transmembrane 4 beta
chr20_+_64066211 0.49 ENST00000458442.1
transcription elongation factor A2
chr2_-_148021490 0.49 ENST00000416719.5
ENST00000264169.6
origin recognition complex subunit 4
chr11_-_62707413 0.48 ENST00000360796.10
ENST00000449636.6
BSCL2 lipid droplet biogenesis associated, seipin
chr5_+_102865805 0.48 ENST00000346918.7
peptidylglycine alpha-amidating monooxygenase
chr12_+_66189254 0.48 ENST00000457197.2
interleukin 1 receptor associated kinase 3
chr1_+_14945775 0.48 ENST00000400797.3
kazrin, periplakin interacting protein
chr1_+_45913647 0.48 ENST00000674079.1
microtubule associated serine/threonine kinase 2
chr14_-_52552493 0.48 ENST00000281741.9
ENST00000557374.1
thioredoxin domain containing 16
chr17_+_1724540 0.48 ENST00000419248.5
ENST00000418841.5
ENST00000409644.6
WD repeat domain 81
chrX_-_10833643 0.48 ENST00000380785.5
ENST00000380787.5
midline 1
chr1_-_206921867 0.48 ENST00000628511.2
ENST00000367091.8
Fc fragment of IgM receptor
chr9_+_6757940 0.47 ENST00000381309.8
lysine demethylase 4C
chr9_-_77648303 0.47 ENST00000341700.7
G protein subunit alpha 14
chr15_-_75455767 0.47 ENST00000360439.8
SIN3 transcription regulator family member A
chr21_-_32813679 0.47 ENST00000487113.1
ENST00000382373.4
chromosome 21 open reading frame 62
chr17_+_60677822 0.47 ENST00000407086.8
ENST00000589222.5
ENST00000626960.2
ENST00000390652.9
BCAS3 microtubule associated cell migration factor
chr14_-_22815421 0.46 ENST00000674313.1
ENST00000555959.1
solute carrier family 7 member 7
chr7_-_120857124 0.46 ENST00000441017.5
ENST00000424710.5
ENST00000433758.5
tetraspanin 12
chr11_+_6390439 0.46 ENST00000530395.1
ENST00000342245.9
ENST00000527275.5
sphingomyelin phosphodiesterase 1
chr20_+_45469745 0.45 ENST00000372676.8
ENST00000217425.9
ENST00000339946.7
WAP four-disulfide core domain 2
chr15_-_52652031 0.45 ENST00000546305.6
family with sequence similarity 214 member A
chr22_+_38656627 0.44 ENST00000411557.5
ENST00000396811.6
ENST00000216029.7
ENST00000416285.5
chibby family member 1, beta catenin antagonist
chr20_+_44531758 0.44 ENST00000372891.7
ENST00000372892.7
ENST00000372894.7
cAMP-dependent protein kinase inhibitor gamma
chr4_-_102760914 0.44 ENST00000505239.1
ENST00000647097.2
mannosidase beta
chr4_-_102760976 0.43 ENST00000644159.1
ENST00000642252.1
mannosidase beta
chr6_+_89562308 0.43 ENST00000522441.5
ankyrin repeat domain 6
chr3_-_120647018 0.43 ENST00000475447.2
homogentisate 1,2-dioxygenase
chr6_-_75493629 0.43 ENST00000393004.6
filamin A interacting protein 1
chr1_-_154956086 0.42 ENST00000368463.8
ENST00000368460.7
ENST00000368465.5
PBX homeobox interacting protein 1
chr20_-_41618362 0.42 ENST00000373222.3
ENST00000373233.8
chromodomain helicase DNA binding protein 6
chr12_+_85874287 0.41 ENST00000551529.5
ENST00000256010.7
neurotensin
chr17_-_7241787 0.41 ENST00000577035.5
GABA type A receptor-associated protein
chr13_-_41061373 0.41 ENST00000405737.2
E74 like ETS transcription factor 1
chr6_-_75493773 0.41 ENST00000237172.12
filamin A interacting protein 1
chr6_-_28923932 0.40 ENST00000377199.4
ENST00000377194.7
tripartite motif containing 27
chr1_+_25616780 0.40 ENST00000374332.9
mannosidase alpha class 1C member 1
chr8_-_78805306 0.40 ENST00000639719.1
ENST00000263851.9
interleukin 7
chr6_-_132734692 0.39 ENST00000509351.5
ENST00000417437.6
ENST00000423615.6
ENST00000427187.6
ENST00000414302.7
ENST00000367927.9
ENST00000450865.2
vanin 3
chr1_-_85578345 0.39 ENST00000426972.8
dimethylarginine dimethylaminohydrolase 1
chr8_-_78805515 0.38 ENST00000379113.6
ENST00000541183.2
interleukin 7
chr14_+_44962177 0.38 ENST00000361462.7
ENST00000361577.7
TOG array regulator of axonemal microtubules 1
chr9_-_13165442 0.38 ENST00000542239.1
ENST00000538841.5
ENST00000433359.6
multiple PDZ domain crumbs cell polarity complex component
chr19_+_49581304 0.38 ENST00000246794.10
proline rich and Gla domain 2
chr14_-_22819721 0.38 ENST00000554517.5
ENST00000285850.11
ENST00000397529.6
ENST00000555702.5
solute carrier family 7 member 7
chr8_-_134510182 0.37 ENST00000521673.5
zinc finger and AT-hook domain containing
chr14_+_24115299 0.37 ENST00000559354.5
ENST00000560459.5
ENST00000559593.5
ENST00000396941.8
ENST00000396936.5
DDB1 and CUL4 associated factor 11
chr3_-_52452828 0.36 ENST00000496590.1
troponin C1, slow skeletal and cardiac type
chr4_+_153257339 0.36 ENST00000676374.1
ENST00000676196.1
ENST00000674935.1
ENST00000674769.1
ENST00000674896.1
ENST00000676191.1
ENST00000675312.1
ENST00000675456.1
ENST00000674847.1
ENST00000675977.1
ENST00000676264.1
ENST00000674726.1
ENST00000676252.1
ENST00000674730.1
ENST00000675738.1
ENST00000482578.3
tripartite motif containing 2
chr20_+_34704336 0.35 ENST00000374809.6
ENST00000374810.8
ENST00000451665.5
tumor protein p53 inducible nuclear protein 2
chr9_-_120477354 0.35 ENST00000416449.5
CDK5 regulatory subunit associated protein 2
chr11_+_72227881 0.35 ENST00000538751.5
ENST00000541756.5
inositol polyphosphate phosphatase like 1
chr7_+_114416286 0.35 ENST00000635534.1
forkhead box P2
chr12_+_12785652 0.35 ENST00000356591.5
apolipoprotein L domain containing 1
chr11_+_1922779 0.35 ENST00000641119.1
ENST00000641225.1
ENST00000641787.1
ENST00000397301.5
ENST00000397304.6
ENST00000446240.1
troponin T3, fast skeletal type
chr6_-_39431313 0.35 ENST00000229913.9
ENST00000394362.5
kinesin family member 6
chr1_+_174875505 0.34 ENST00000486220.5
RAB GTPase activating protein 1 like
chr17_+_7558774 0.34 ENST00000396545.4
TNF superfamily member 13
chr5_+_43603163 0.33 ENST00000660752.1
ENST00000654405.1
ENST00000344920.9
ENST00000657172.1
ENST00000512996.6
ENST00000671668.1
nicotinamide nucleotide transhydrogenase
chr17_-_39927549 0.33 ENST00000579695.5
ENST00000304046.7
ORMDL sphingolipid biosynthesis regulator 3
chr20_+_54475584 0.33 ENST00000262593.10
docking protein 5
chr8_+_97775829 0.33 ENST00000517924.5
lysosomal protein transmembrane 4 beta
chr17_+_7558712 0.33 ENST00000338784.9
ENST00000625791.2
TNF superfamily member 13
chr8_-_73878816 0.32 ENST00000602593.6
ENST00000651945.1
ENST00000419880.7
ENST00000517608.5
ENST00000650817.1
ubiquitin conjugating enzyme E2 W
chr6_-_31684040 0.32 ENST00000375863.7
lymphocyte antigen 6 family member G5C
chr2_+_96537254 0.31 ENST00000454558.2
AT-rich interaction domain 5A
chr8_-_65789084 0.31 ENST00000379419.8
phosphodiesterase 7A
chr11_-_796185 0.31 ENST00000533385.5
ENST00000528936.5
ENST00000629634.2
ENST00000625752.2
ENST00000528606.5
ENST00000320230.9
solute carrier family 25 member 22
chr1_-_68449927 0.31 ENST00000262340.6
retinoid isomerohydrolase RPE65
chrX_-_9765839 0.31 ENST00000467482.6
G protein-coupled receptor 143
chr12_-_49903853 0.31 ENST00000320634.8
Fas apoptotic inhibitory molecule 2
chr6_-_139291987 0.31 ENST00000358430.8
taxilin beta
chr8_-_70669142 0.31 ENST00000522447.5
ENST00000276590.5
lactamase beta 2
chr5_+_146203593 0.31 ENST00000265271.7
RNA binding motif protein 27
chr16_-_5097742 0.30 ENST00000587133.1
ENST00000458008.8
ENST00000427587.9
eukaryotic elongation factor 2 lysine methyltransferase
chr19_+_6772699 0.30 ENST00000602142.6
ENST00000304076.6
ENST00000596764.5
vav guanine nucleotide exchange factor 1
chr5_+_142771119 0.30 ENST00000642734.1
Rho GTPase activating protein 26
chr6_+_44216914 0.30 ENST00000573382.3
ENST00000576476.1
myomixer, myoblast fusion factor
chr20_+_54475647 0.30 ENST00000395939.5
docking protein 5
chr16_+_83899079 0.29 ENST00000262430.6
malonyl-CoA decarboxylase
chr8_-_94949350 0.29 ENST00000448464.6
ENST00000342697.5
tumor protein p53 inducible nuclear protein 1
chr1_+_159780930 0.29 ENST00000368109.5
ENST00000368108.7
ENST00000368107.2
dual specificity phosphatase 23
chr6_-_31729260 0.29 ENST00000375789.7
dimethylarginine dimethylaminohydrolase 2
chr17_-_181640 0.29 ENST00000613549.3
double C2 domain beta
chr11_+_66509079 0.28 ENST00000419755.3
novel protein
chr2_+_96536743 0.28 ENST00000673792.1
ENST00000357485.8
AT-rich interaction domain 5A
chr6_-_31729785 0.28 ENST00000416410.6
dimethylarginine dimethylaminohydrolase 2
chr6_-_31729478 0.28 ENST00000436437.2
dimethylarginine dimethylaminohydrolase 2
chr3_-_52835011 0.28 ENST00000446157.3
musculoskeletal, embryonic nuclear protein 1
chr17_-_49678074 0.28 ENST00000505581.5
ENST00000504102.6
ENST00000514121.6
ENST00000393328.6
ENST00000509079.6
ENST00000347630.6
speckle type BTB/POZ protein
chr9_+_2159850 0.28 ENST00000416751.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr3_-_52834901 0.28 ENST00000486659.5
musculoskeletal, embryonic nuclear protein 1
chr9_+_89605004 0.28 ENST00000252506.11
ENST00000375769.1
growth arrest and DNA damage inducible gamma
chr3_-_49021045 0.28 ENST00000440857.5
DALR anticodon binding domain containing 3
chr7_-_128031422 0.27 ENST00000249363.4
leucine rich repeat containing 4
chr2_+_68157877 0.27 ENST00000263657.7
partner of NOB1 homolog
chr1_-_15944348 0.27 ENST00000444358.1
zinc finger and BTB domain containing 17
chr6_+_156779363 0.27 ENST00000494260.2
ENST00000636748.1
ENST00000636607.1
ENST00000414678.7
ENST00000638000.1
AT-rich interaction domain 1B
chr8_-_38150943 0.27 ENST00000276449.9
steroidogenic acute regulatory protein
chr9_+_132670458 0.26 ENST00000372146.5
general transcription factor IIIC subunit 4
chr2_-_212124901 0.26 ENST00000402597.6
erb-b2 receptor tyrosine kinase 4
chr3_-_65597886 0.26 ENST00000460329.6
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr1_+_40709475 0.26 ENST00000372651.5
nuclear transcription factor Y subunit gamma
chr12_-_52473798 0.26 ENST00000252250.7
keratin 6C
chr12_-_123268244 0.26 ENST00000618072.4
cyclin dependent kinase 2 associated protein 1
chr11_-_85719045 0.25 ENST00000533057.6
ENST00000533892.5
synaptotagmin like 2
chr10_+_101031223 0.25 ENST00000393459.5
ENST00000224807.9
sideroflexin 3
chr19_-_45782388 0.25 ENST00000458663.6
DM1 protein kinase
chr12_-_64759395 0.25 ENST00000258145.8
ENST00000543646.5
ENST00000542058.5
glucosamine (N-acetyl)-6-sulfatase
chr17_-_37609361 0.25 ENST00000614941.4
ENST00000619541.4
ENST00000622045.4
ENST00000616179.4
ENST00000621136.4
ENST00000612223.5
ENST00000620424.1
synergin gamma
chrX_-_123623155 0.25 ENST00000618150.4
THO complex 2
chr14_-_77028663 0.25 ENST00000238647.5
interferon regulatory factor 2 binding protein like
chr2_-_148020754 0.25 ENST00000440042.1
ENST00000536575.5
origin recognition complex subunit 4
chr2_+_134254065 0.25 ENST00000281923.4
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase
chr17_-_49677976 0.25 ENST00000665825.1
ENST00000508805.5
ENST00000515508.6
ENST00000451526.6
ENST00000507970.5
speckle type BTB/POZ protein
chr19_+_7522605 0.24 ENST00000264079.11
mucolipin TRP cation channel 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.5 GO:2001107 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.5 4.6 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.4 1.2 GO:0010931 macrophage tolerance induction(GO:0010931) regulation of macrophage tolerance induction(GO:0010932) positive regulation of macrophage tolerance induction(GO:0010933)
0.4 1.2 GO:0021524 visceral motor neuron differentiation(GO:0021524) cardiac cell fate determination(GO:0060913) positive regulation of granulocyte colony-stimulating factor production(GO:0071657) positive regulation of macrophage colony-stimulating factor production(GO:1901258)
0.4 4.5 GO:0006824 cobalt ion transport(GO:0006824)
0.3 1.0 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.3 0.9 GO:0003032 detection of oxygen(GO:0003032)
0.3 1.2 GO:0035284 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.3 0.9 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.3 3.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 1.6 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.2 0.5 GO:0035638 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.2 1.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.2 0.5 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 1.3 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1 1.9 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.5 GO:0018032 protein amidation(GO:0018032)
0.1 0.8 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 0.4 GO:0002086 diaphragm contraction(GO:0002086)
0.1 0.4 GO:0021757 caudate nucleus development(GO:0021757) putamen development(GO:0021758)
0.1 1.7 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.3 GO:1902908 regulation of melanosome transport(GO:1902908)
0.1 1.1 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 0.4 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.1 0.4 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 1.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.3 GO:0033869 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.1 0.3 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.1 0.3 GO:0018963 phthalate metabolic process(GO:0018963) positive regulation of bile acid biosynthetic process(GO:0070859) cellular response to luteinizing hormone stimulus(GO:0071373) positive regulation of bile acid metabolic process(GO:1904253)
0.1 0.4 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.1 0.3 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.1 0.5 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.3 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.1 0.2 GO:0090274 regulation of somatostatin secretion(GO:0090273) positive regulation of somatostatin secretion(GO:0090274)
0.1 2.3 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 0.3 GO:1900108 inner medullary collecting duct development(GO:0072061) negative regulation of nodal signaling pathway(GO:1900108)
0.1 1.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 1.4 GO:0006527 arginine catabolic process(GO:0006527)
0.1 2.3 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.2 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.5 GO:0044334 canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.1 0.2 GO:1903892 negative regulation of ATF6-mediated unfolded protein response(GO:1903892)
0.1 0.3 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.5 GO:0023021 termination of signal transduction(GO:0023021)
0.1 1.0 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 0.4 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.4 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 0.3 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.3 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.1 0.3 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.1 0.2 GO:0099403 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.0 0.2 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.0 0.7 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.5 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.2 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.0 0.2 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.0 0.8 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.6 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.5 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 1.1 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 4.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 2.0 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.2 GO:0019086 late viral transcription(GO:0019086)
0.0 0.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.6 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.5 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.2 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.9 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.3 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.9 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.0 3.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.2 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.7 GO:0002467 germinal center formation(GO:0002467)
0.0 0.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.4 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.2 GO:0009838 abscission(GO:0009838)
0.0 0.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:2000809 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.2 GO:1904970 brush border assembly(GO:1904970)
0.0 0.4 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 2.0 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.2 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 2.5 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.1 GO:0035936 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.0 0.3 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.4 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.5 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0016476 calcium-dependent cell-matrix adhesion(GO:0016340) regulation of embryonic cell shape(GO:0016476)
0.0 0.2 GO:0044597 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0 0.4 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.2 GO:0090650 glycerol transport(GO:0015793) urea transport(GO:0015840) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 1.2 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.5 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 1.8 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 1.9 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:1904640 response to methionine(GO:1904640)
0.0 0.1 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.3 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 1.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.5 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.2 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.0 0.1 GO:0046103 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.0 0.2 GO:0001554 luteolysis(GO:0001554)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.2 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.4 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:1905066 positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.0 0.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.3 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.4 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.3 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.3 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 1.2 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.1 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0 0.1 GO:0048669 astrocyte activation involved in immune response(GO:0002265) microglia differentiation(GO:0014004) microglia development(GO:0014005) collateral sprouting in absence of injury(GO:0048669) smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.3 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.5 GO:0010842 retina layer formation(GO:0010842)
0.0 0.4 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.6 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.6 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.3 3.5 GO:0060171 stereocilium membrane(GO:0060171)
0.2 2.8 GO:0097427 microtubule bundle(GO:0097427)
0.2 3.1 GO:0097433 dense body(GO:0097433)
0.2 1.7 GO:0044294 dendritic growth cone(GO:0044294)
0.1 1.0 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.3 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.4 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 3.7 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.5 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.2 GO:0072534 perineuronal net(GO:0072534)
0.0 5.8 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.4 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.2 GO:1990393 3M complex(GO:1990393)
0.0 0.9 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.3 GO:0030061 mitochondrial crista(GO:0030061)
0.0 1.3 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 4.8 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.4 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.3 GO:0005883 neurofilament(GO:0005883)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.0 0.7 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.4 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.5 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 2.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 1.6 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 1.0 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.6 GO:0031201 SNARE complex(GO:0031201)
0.0 0.4 GO:0042629 mast cell granule(GO:0042629)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.3 4.5 GO:0031419 cobalamin binding(GO:0031419)
0.2 1.9 GO:0050682 AF-2 domain binding(GO:0050682)
0.2 1.4 GO:0016403 dimethylargininase activity(GO:0016403)
0.2 0.9 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 0.5 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.9 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.5 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 1.7 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.3 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.4 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.5 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 1.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 3.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 3.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 1.3 GO:0015923 mannosidase activity(GO:0015923)
0.1 1.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 1.8 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.7 GO:0031013 troponin I binding(GO:0031013)
0.1 1.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 1.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.2 GO:0090541 MIT domain binding(GO:0090541)
0.1 0.7 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 1.0 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.3 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.3 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.1 0.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.8 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.3 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.1 GO:0052816 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
0.0 0.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 1.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.4 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 1.0 GO:0070410 co-SMAD binding(GO:0070410)
0.0 1.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 4.7 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.5 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.4 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0035731 S-nitrosoglutathione binding(GO:0035730) dinitrosyl-iron complex binding(GO:0035731)
0.0 0.8 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.6 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.3 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.3 GO:0035240 dopamine binding(GO:0035240)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 2.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.0 GO:0004952 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588) dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 1.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.7 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.7 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.9 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.9 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.5 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.0 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.0 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.8 PID INSULIN PATHWAY Insulin Pathway
0.0 0.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.3 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 2.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 2.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.0 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.9 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.0 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 2.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.1 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.7 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.7 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing