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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for TFCP2L1

Z-value: 0.82

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Transcription factors associated with TFCP2L1

Gene Symbol Gene ID Gene Info
TFCP2L1
ENSG00000115112.8 TFCP2L1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFCP2L1hg38_v1_chr2_-_121285194_1212852090.301.1e-01Click!

Activity profile of TFCP2L1 motif

Sorted Z-values of TFCP2L1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TFCP2L1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr20_-_44651683 2.54 ENST00000537820.1
ENST00000372874.9
ADA
adenosine deaminase
chr8_-_6877928 1.89 ENST00000297439.4
DEFB1
defensin beta 1
chr18_+_23949847 1.86 ENST00000588004.1
LAMA3
laminin subunit alpha 3
chr2_-_72147819 1.69 ENST00000001146.7
ENST00000546307.5
ENST00000474509.1
CYP26B1
cytochrome P450 family 26 subfamily B member 1
chr1_+_116111395 1.68 ENST00000684484.1
ENST00000369500.4
MAB21L3
mab-21 like 3
chr2_-_31138429 1.64 ENST00000349752.10
GALNT14
polypeptide N-acetylgalactosaminyltransferase 14
chr8_+_53851786 1.64 ENST00000297313.8
ENST00000344277.10
RGS20
regulator of G protein signaling 20
chr12_+_53097656 1.63 ENST00000301464.4
IGFBP6
insulin like growth factor binding protein 6
chr22_+_31093358 1.54 ENST00000404574.5
SMTN
smoothelin
chr4_+_8199363 1.52 ENST00000382521.7
ENST00000457650.7
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr10_+_100347225 1.51 ENST00000370355.3
SCD
stearoyl-CoA desaturase
chr4_+_8199239 1.51 ENST00000245105.8
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr2_+_11746576 1.42 ENST00000256720.6
ENST00000674199.1
ENST00000441684.5
ENST00000423495.1
LPIN1
lipin 1
chr12_-_119803383 1.42 ENST00000392520.2
ENST00000678677.1
ENST00000679249.1
ENST00000676849.1
CIT
citron rho-interacting serine/threonine kinase
chr12_+_40692413 1.36 ENST00000551295.7
ENST00000547702.5
ENST00000551424.5
CNTN1
contactin 1
chr11_-_62556230 1.29 ENST00000530285.5
AHNAK
AHNAK nucleoprotein
chr9_+_130053706 1.23 ENST00000372410.7
GPR107
G protein-coupled receptor 107
chr21_-_15064934 1.18 ENST00000400199.5
ENST00000400202.5
ENST00000318948.7
NRIP1
nuclear receptor interacting protein 1
chr4_-_121823843 1.10 ENST00000274026.10
CCNA2
cyclin A2
chr7_-_128405930 1.07 ENST00000470772.5
ENST00000480861.5
ENST00000496200.5
IMPDH1
inosine monophosphate dehydrogenase 1
chr12_+_119178920 1.05 ENST00000281938.7
HSPB8
heat shock protein family B (small) member 8
chr12_+_119178953 1.03 ENST00000674542.1
HSPB8
heat shock protein family B (small) member 8
chr20_+_45881218 1.03 ENST00000372523.1
ZSWIM1
zinc finger SWIM-type containing 1
chr19_+_47713412 1.02 ENST00000538399.1
ENST00000263277.8
EHD2
EH domain containing 2
chr1_-_155990062 1.02 ENST00000462460.6
ARHGEF2
Rho/Rac guanine nucleotide exchange factor 2
chr19_-_42412347 1.01 ENST00000601189.1
ENST00000599211.1
LIPE
lipase E, hormone sensitive type
chr20_-_54173976 1.00 ENST00000216862.8
CYP24A1
cytochrome P450 family 24 subfamily A member 1
chr9_-_124507382 0.93 ENST00000373588.9
ENST00000620110.4
NR5A1
nuclear receptor subfamily 5 group A member 1
chr22_-_37427433 0.92 ENST00000452946.1
ENST00000402918.7
ELFN2
ELFN2
extracellular leucine rich repeat and fibronectin type III domain containing 2
extracellular leucine rich repeat and fibronectin type III domain containing 2
chr11_+_111245725 0.91 ENST00000280325.7
C11orf53
chromosome 11 open reading frame 53
chrX_-_107717054 0.88 ENST00000503515.1
ENST00000372397.6
TSC22D3
TSC22 domain family member 3
chr8_+_49072335 0.87 ENST00000399653.8
ENST00000522267.6
ENST00000303202.8
PPDPFL
pancreatic progenitor cell differentiation and proliferation factor like
chr14_-_106025628 0.86 ENST00000631943.1
IGHV7-4-1
immunoglobulin heavy variable 7-4-1
chr12_-_121274510 0.86 ENST00000392474.6
CAMKK2
calcium/calmodulin dependent protein kinase kinase 2
chr2_+_11724333 0.82 ENST00000425416.6
ENST00000396097.5
LPIN1
lipin 1
chr1_-_26354080 0.81 ENST00000308182.10
CRYBG2
crystallin beta-gamma domain containing 2
chr11_+_78188871 0.79 ENST00000528910.5
ENST00000529308.6
USP35
ubiquitin specific peptidase 35
chr16_+_46884323 0.79 ENST00000340124.9
GPT2
glutamic--pyruvic transaminase 2
chr19_+_14583076 0.79 ENST00000547437.5
ENST00000417570.6
CLEC17A
C-type lectin domain containing 17A
chr19_-_46413548 0.76 ENST00000307522.5
CCDC8
coiled-coil domain containing 8
chr11_+_62881686 0.74 ENST00000536981.6
ENST00000539891.6
SLC3A2
solute carrier family 3 member 2
chr1_-_161550591 0.73 ENST00000367967.7
ENST00000436743.6
ENST00000442336.1
FCGR3A
Fc fragment of IgG receptor IIIa
chr14_-_68937942 0.73 ENST00000684182.1
ACTN1
actinin alpha 1
chr11_+_95089804 0.72 ENST00000278505.5
ENDOD1
endonuclease domain containing 1
chr17_-_76027212 0.71 ENST00000586740.1
EVPL
envoplakin
chr7_+_151956379 0.69 ENST00000431418.6
GALNTL5
polypeptide N-acetylgalactosaminyltransferase like 5
chrX_-_64205680 0.67 ENST00000374869.8
AMER1
APC membrane recruitment protein 1
chr7_+_151956440 0.67 ENST00000392800.7
ENST00000616416.4
GALNTL5
polypeptide N-acetylgalactosaminyltransferase like 5
chr14_+_64504574 0.66 ENST00000358738.3
ZBTB1
zinc finger and BTB domain containing 1
chr1_-_161549793 0.66 ENST00000443193.6
FCGR3A
Fc fragment of IgG receptor IIIa
chr1_-_161549892 0.66 ENST00000426740.7
FCGR3A
Fc fragment of IgG receptor IIIa
chr19_-_1822038 0.66 ENST00000643515.1
REXO1
RNA exonuclease 1 homolog
chr2_+_90234809 0.65 ENST00000443397.5
IGKV3D-7
immunoglobulin kappa variable 3D-7
chr17_-_76027296 0.65 ENST00000301607.8
EVPL
envoplakin
chr19_+_41219177 0.65 ENST00000301178.9
AXL
AXL receptor tyrosine kinase
chr15_+_74615808 0.63 ENST00000395066.9
ENST00000568139.6
ENST00000563297.5
ENST00000568488.6
CLK3
CDC like kinase 3
chr9_+_130053897 0.61 ENST00000347136.11
ENST00000610997.1
GPR107
G protein-coupled receptor 107
chr17_+_40015428 0.60 ENST00000394149.8
ENST00000225474.6
ENST00000331769.6
ENST00000394148.7
ENST00000577675.1
CSF3
colony stimulating factor 3
chr14_-_68979076 0.57 ENST00000538545.6
ENST00000684639.1
ACTN1
actinin alpha 1
chr1_+_11934651 0.57 ENST00000449038.5
ENST00000196061.5
ENST00000429000.6
PLOD1
procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
chrX_-_50200988 0.57 ENST00000358526.7
AKAP4
A-kinase anchoring protein 4
chr14_-_68979251 0.57 ENST00000438964.6
ENST00000679147.1
ACTN1
actinin alpha 1
chr4_-_993430 0.56 ENST00000361661.6
ENST00000622731.4
SLC26A1
solute carrier family 26 member 1
chr2_+_71453538 0.56 ENST00000258104.8
DYSF
dysferlin
chr1_-_201115372 0.55 ENST00000458416.2
ASCL5
achaete-scute family bHLH transcription factor 5
chr14_-_68979274 0.55 ENST00000394419.9
ACTN1
actinin alpha 1
chr10_-_119536533 0.55 ENST00000392865.5
RGS10
regulator of G protein signaling 10
chr14_-_68979314 0.52 ENST00000684713.1
ENST00000683198.1
ENST00000684598.1
ENST00000682331.1
ENST00000682291.1
ENST00000683342.1
ACTN1
actinin alpha 1
chr17_+_18377769 0.52 ENST00000399134.5
EVPLL
envoplakin like
chr2_+_233251694 0.52 ENST00000417017.5
ENST00000392020.8
ENST00000392018.1
ATG16L1
autophagy related 16 like 1
chr15_-_82699893 0.51 ENST00000642989.2
AP3B2
adaptor related protein complex 3 subunit beta 2
chr14_-_68979436 0.51 ENST00000193403.10
ACTN1
actinin alpha 1
chr17_-_1492660 0.50 ENST00000648651.1
MYO1C
myosin IC
chr7_+_77538059 0.50 ENST00000435495.6
PTPN12
protein tyrosine phosphatase non-receptor type 12
chr7_-_100158679 0.50 ENST00000456769.5
ENST00000316937.8
TRAPPC14
trafficking protein particle complex 14
chr12_-_53232182 0.50 ENST00000425354.7
ENST00000546717.1
ENST00000394426.5
RARG
retinoic acid receptor gamma
chr2_+_233251571 0.50 ENST00000347464.9
ENST00000444735.5
ENST00000373525.9
ENST00000392017.9
ENST00000419681.5
ATG16L1
autophagy related 16 like 1
chr18_+_50560070 0.49 ENST00000400384.7
ENST00000540640.3
ENST00000592595.5
MAPK4
mitogen-activated protein kinase 4
chr3_+_26622800 0.48 ENST00000396641.6
LRRC3B
leucine rich repeat containing 3B
chr1_-_155978524 0.47 ENST00000361247.9
ARHGEF2
Rho/Rac guanine nucleotide exchange factor 2
chr1_-_161631032 0.47 ENST00000534776.1
ENST00000613418.4
ENST00000614870.4
FCGR3B
Fc fragment of IgG receptor IIIb
chr5_+_140360187 0.47 ENST00000506757.7
ENST00000506545.5
ENST00000432095.6
ENST00000507527.1
SLC4A9
solute carrier family 4 member 9
chr11_-_86068743 0.46 ENST00000356360.9
PICALM
phosphatidylinositol binding clathrin assembly protein
chr22_+_31160171 0.46 ENST00000326132.11
ENST00000426256.6
ENST00000266252.8
RNF185
ring finger protein 185
chr1_-_161631152 0.46 ENST00000421702.3
ENST00000650385.1
FCGR3B
Fc fragment of IgG receptor IIIb
chr5_-_152405277 0.46 ENST00000255262.4
NMUR2
neuromedin U receptor 2
chr14_-_106154113 0.46 ENST00000390603.2
IGHV3-15
immunoglobulin heavy variable 3-15
chr11_-_86068929 0.45 ENST00000630913.2
PICALM
phosphatidylinositol binding clathrin assembly protein
chr11_+_62613236 0.44 ENST00000278833.4
ROM1
retinal outer segment membrane protein 1
chr22_-_38088915 0.44 ENST00000428572.1
BAIAP2L2
BAR/IMD domain containing adaptor protein 2 like 2
chrX_-_132218124 0.43 ENST00000342983.6
RAP2C
RAP2C, member of RAS oncogene family
chr12_+_55931148 0.43 ENST00000549629.5
ENST00000555218.5
ENST00000331886.10
DGKA
diacylglycerol kinase alpha
chr19_+_38930916 0.42 ENST00000308018.9
ENST00000407800.2
ENST00000402029.3
MRPS12
mitochondrial ribosomal protein S12
chr10_+_97589715 0.42 ENST00000370640.5
C10orf62
chromosome 10 open reading frame 62
chr9_-_34637719 0.41 ENST00000378892.5
ENST00000680277.1
ENST00000277010.9
ENST00000679597.1
ENST00000680244.1
SIGMAR1
sigma non-opioid intracellular receptor 1
chr19_+_40717091 0.41 ENST00000263370.3
ITPKC
inositol-trisphosphate 3-kinase C
chr5_-_36241798 0.41 ENST00000514504.5
NADK2
NAD kinase 2, mitochondrial
chr5_-_177496845 0.41 ENST00000506537.1
PDLIM7
PDZ and LIM domain 7
chr3_-_50340804 0.40 ENST00000359365.9
ENST00000357043.6
RASSF1
Ras association domain family member 1
chr10_+_122163590 0.40 ENST00000368999.5
TACC2
transforming acidic coiled-coil containing protein 2
chr3_-_50340933 0.39 ENST00000616212.4
RASSF1
Ras association domain family member 1
chr3_-_48635426 0.39 ENST00000455886.6
ENST00000431739.5
ENST00000426599.1
ENST00000383733.7
ENST00000395550.7
ENST00000420764.6
ENST00000337000.12
SLC26A6
solute carrier family 26 member 6
chr10_+_104641282 0.39 ENST00000369701.8
SORCS3
sortilin related VPS10 domain containing receptor 3
chr22_-_38755458 0.39 ENST00000405510.5
ENST00000433561.5
SUN2
Sad1 and UNC84 domain containing 2
chr4_+_40193642 0.39 ENST00000617441.4
ENST00000503941.5
RHOH
ras homolog family member H
chr2_+_71453722 0.39 ENST00000409582.7
ENST00000409762.5
ENST00000413539.6
ENST00000429174.6
DYSF
dysferlin
chr5_-_177496802 0.39 ENST00000506161.5
PDLIM7
PDZ and LIM domain 7
chr6_-_3751703 0.38 ENST00000380283.5
PXDC1
PX domain containing 1
chr20_-_31870510 0.38 ENST00000339738.10
DUSP15
dual specificity phosphatase 15
chr2_+_9206762 0.38 ENST00000315273.4
ENST00000281419.8
ASAP2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr8_-_53842899 0.38 ENST00000524234.1
ENST00000521275.5
ENST00000396774.6
ATP6V1H
ATPase H+ transporting V1 subunit H
chr12_-_120369156 0.37 ENST00000257552.7
MSI1
musashi RNA binding protein 1
chr9_-_34637800 0.36 ENST00000680730.1
ENST00000477726.1
SIGMAR1
sigma non-opioid intracellular receptor 1
chr19_-_18543483 0.36 ENST00000597547.1
ENST00000222308.8
FKBP8
FKBP prolyl isomerase 8
chr1_+_151540299 0.36 ENST00000392712.7
ENST00000368848.6
ENST00000368849.8
ENST00000353024.4
TUFT1
tuftelin 1
chr2_-_168247569 0.36 ENST00000355999.5
STK39
serine/threonine kinase 39
chr17_+_7355123 0.36 ENST00000389982.8
ENST00000576060.6
ENST00000330767.4
TMEM95
transmembrane protein 95
chr19_+_33621944 0.36 ENST00000650847.1
ENST00000591231.5
ENST00000434302.5
ENST00000438847.7
CHST8
carbohydrate sulfotransferase 8
chr12_-_48106042 0.35 ENST00000551798.1
ENST00000549518.6
SENP1
SUMO specific peptidase 1
chr10_+_122163426 0.35 ENST00000360561.7
TACC2
transforming acidic coiled-coil containing protein 2
chr19_+_4909430 0.35 ENST00000620565.4
ENST00000613817.4
ENST00000624301.3
ENST00000650932.1
UHRF1
ubiquitin like with PHD and ring finger domains 1
chr3_-_151316795 0.35 ENST00000260843.5
GPR87
G protein-coupled receptor 87
chr19_-_18542971 0.35 ENST00000596558.6
FKBP8
FKBP prolyl isomerase 8
chr7_+_74083785 0.35 ENST00000336180.7
LIMK1
LIM domain kinase 1
chr1_-_156248038 0.35 ENST00000470198.5
ENST00000292291.10
ENST00000356983.7
PAQR6
progestin and adipoQ receptor family member 6
chr19_+_45251363 0.35 ENST00000620044.4
MARK4
microtubule affinity regulating kinase 4
chr4_-_163332589 0.35 ENST00000296533.3
ENST00000509586.5
ENST00000504391.5
ENST00000512819.1
NPY1R
neuropeptide Y receptor Y1
chr8_-_116766255 0.34 ENST00000276682.8
EIF3H
eukaryotic translation initiation factor 3 subunit H
chr17_-_45410414 0.34 ENST00000532038.5
ENST00000528677.1
ARHGAP27
Rho GTPase activating protein 27
chr19_-_9818808 0.33 ENST00000586651.5
ENST00000586073.1
FBXL12
F-box and leucine rich repeat protein 12
chr15_+_75724034 0.33 ENST00000332145.3
ODF3L1
outer dense fiber of sperm tails 3 like 1
chr3_-_48188356 0.33 ENST00000351231.7
ENST00000437972.1
ENST00000302506.8
CDC25A
cell division cycle 25A
chr19_+_18612848 0.32 ENST00000262817.8
TMEM59L
transmembrane protein 59 like
chr10_+_122163672 0.32 ENST00000369004.7
ENST00000260733.7
TACC2
transforming acidic coiled-coil containing protein 2
chr2_+_231781669 0.32 ENST00000410024.5
ENST00000611614.4
ENST00000409295.5
ENST00000409091.5
COPS7B
COP9 signalosome subunit 7B
chr5_+_141475928 0.32 ENST00000611950.1
ENST00000308177.5
ENST00000617641.4
ENST00000621008.1
ENST00000617222.4
PCDHGC3
protocadherin gamma subfamily C, 3
chr2_+_181891974 0.32 ENST00000409001.5
ITPRID2
ITPR interacting domain containing 2
chr14_+_92652468 0.32 ENST00000556418.1
RIN3
Ras and Rab interactor 3
chr19_+_48465837 0.32 ENST00000595676.1
ENSG00000268465.1
novel protein
chr19_+_45251249 0.32 ENST00000262891.9
ENST00000300843.8
MARK4
microtubule affinity regulating kinase 4
chr19_+_41354145 0.32 ENST00000604123.5
TMEM91
transmembrane protein 91
chr12_+_48106094 0.31 ENST00000546755.5
ENST00000549366.5
ENST00000642730.1
ENST00000552792.5
PFKM
phosphofructokinase, muscle
chr1_-_211133945 0.31 ENST00000640044.1
ENST00000640566.1
KCNH1
potassium voltage-gated channel subfamily H member 1
chr10_+_100745711 0.31 ENST00000370296.6
ENST00000428433.5
PAX2
paired box 2
chr8_-_97277890 0.31 ENST00000322128.5
TSPYL5
TSPY like 5
chr1_-_156248013 0.31 ENST00000368270.2
PAQR6
progestin and adipoQ receptor family member 6
chr19_-_20661507 0.30 ENST00000612591.4
ENST00000595405.1
ZNF626
zinc finger protein 626
chr1_+_26863140 0.30 ENST00000339276.6
SFN
stratifin
chr13_+_20703677 0.30 ENST00000682841.1
IL17D
interleukin 17D
chr17_+_7420315 0.30 ENST00000323675.4
SPEM1
spermatid maturation 1
chr6_-_31795627 0.30 ENST00000375663.8
VARS1
valyl-tRNA synthetase 1
chr19_-_9819032 0.29 ENST00000590277.1
ENST00000588922.5
ENST00000589626.5
ENST00000247977.9
ENST00000592067.1
ENST00000586469.1
FBXL12
F-box and leucine rich repeat protein 12
chr5_+_96663010 0.29 ENST00000506811.5
ENST00000514055.5
ENST00000508608.6
CAST
calpastatin
chr17_-_16569184 0.29 ENST00000448349.2
ENST00000395825.4
ZNF287
zinc finger protein 287
chr17_+_42844573 0.29 ENST00000253799.8
ENST00000452774.2
AOC2
amine oxidase copper containing 2
chr2_+_26764232 0.29 ENST00000344420.10
SLC35F6
solute carrier family 35 member F6
chr2_+_181891697 0.28 ENST00000431877.7
ITPRID2
ITPR interacting domain containing 2
chr2_+_181891904 0.28 ENST00000320370.11
ITPRID2
ITPR interacting domain containing 2
chr8_-_27992624 0.28 ENST00000524352.5
SCARA5
scavenger receptor class A member 5
chr2_+_102619531 0.28 ENST00000233969.3
SLC9A2
solute carrier family 9 member A2
chr15_-_89690775 0.28 ENST00000559170.1
PEX11A
peroxisomal biogenesis factor 11 alpha
chr10_+_63133247 0.28 ENST00000435510.6
NRBF2
nuclear receptor binding factor 2
chr17_-_41027198 0.28 ENST00000361883.6
KRTAP1-5
keratin associated protein 1-5
chr19_-_6375849 0.27 ENST00000245810.1
PSPN
persephin
chr15_-_89690634 0.27 ENST00000561257.1
PEX11A
peroxisomal biogenesis factor 11 alpha
chr1_-_207032749 0.27 ENST00000359470.6
ENST00000461135.2
C1orf116
chromosome 1 open reading frame 116
chr17_-_16569169 0.27 ENST00000395824.5
ZNF287
zinc finger protein 287
chr4_+_146638890 0.26 ENST00000281321.3
POU4F2
POU class 4 homeobox 2
chr10_+_63133279 0.26 ENST00000277746.11
NRBF2
nuclear receptor binding factor 2
chr4_-_10116779 0.26 ENST00000499869.7
WDR1
WD repeat domain 1
chr15_+_60004305 0.26 ENST00000396057.6
FOXB1
forkhead box B1
chr5_-_141619049 0.26 ENST00000647433.1
ENST00000253811.10
ENST00000389057.9
ENST00000398557.8
DIAPH1
diaphanous related formin 1
chr12_+_93574965 0.26 ENST00000551883.1
ENST00000549510.1
SOCS2
suppressor of cytokine signaling 2
chr6_+_31587185 0.25 ENST00000376092.7
ENST00000376086.7
ENST00000303757.12
ENST00000376093.6
LST1
leukocyte specific transcript 1
chr10_+_100745570 0.25 ENST00000427256.6
ENST00000355243.8
PAX2
paired box 2
chr5_+_150671588 0.25 ENST00000523553.1
MYOZ3
myozenin 3
chr22_+_20131781 0.25 ENST00000334554.12
ENST00000320602.11
ENST00000405930.3
ZDHHC8
zinc finger DHHC-type palmitoyltransferase 8
chr11_+_18322253 0.25 ENST00000453096.6
GTF2H1
general transcription factor IIH subunit 1
chr3_+_184362599 0.25 ENST00000455712.5
POLR2H
RNA polymerase II, I and III subunit H
chr14_-_106803221 0.25 ENST00000390636.2
IGHV3-73
immunoglobulin heavy variable 3-73
chr19_+_10602436 0.24 ENST00000590382.5
ENST00000407327.8
SLC44A2
solute carrier family 44 member 2
chr1_-_161132577 0.24 ENST00000464113.1
DEDD
death effector domain containing
chr1_+_20290869 0.24 ENST00000289815.13
ENST00000375079.6
VWA5B1
von Willebrand factor A domain containing 5B1
chr12_+_57772648 0.24 ENST00000333012.5
EEF1AKMT3
EEF1A lysine methyltransferase 3
chr20_+_45406035 0.23 ENST00000372723.7
ENST00000372722.7
DBNDD2
dysbindin domain containing 2
chr2_-_46941710 0.23 ENST00000409207.5
MCFD2
multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
chr20_+_63235899 0.23 ENST00000217169.8
BIRC7
baculoviral IAP repeat containing 7
chr5_-_141618957 0.23 ENST00000389054.8
DIAPH1
diaphanous related formin 1
chr5_-_141618914 0.23 ENST00000518047.5
DIAPH1
diaphanous related formin 1
chr2_-_20012661 0.23 ENST00000421259.2
ENST00000407540.8
MATN3
matrilin 3
chr12_+_57772587 0.22 ENST00000300209.13
EEF1AKMT3
EEF1A lysine methyltransferase 3
chr11_-_86069043 0.22 ENST00000532317.5
ENST00000528256.1
ENST00000393346.8
ENST00000526033.5
PICALM
phosphatidylinositol binding clathrin assembly protein
chr4_+_56435730 0.22 ENST00000514888.5
ENST00000264221.6
ENST00000505164.5
PAICS
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
chr10_+_100746197 0.22 ENST00000361791.7
PAX2
paired box 2
chr2_+_71068636 0.22 ENST00000244204.11
ENST00000533981.5
NAGK
N-acetylglucosamine kinase
chr6_-_31582415 0.22 ENST00000429299.3
ENST00000446745.2
LTB
lymphotoxin beta
chr3_-_71753582 0.22 ENST00000295612.7
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr2_-_27071628 0.22 ENST00000447619.5
ENST00000429985.1
ENST00000456793.2
OST4
oligosaccharyltransferase complex subunit 4, non-catalytic
chr3_+_52287811 0.22 ENST00000305690.12
ENST00000473032.5
ENST00000436784.7
ENST00000471180.5
GLYCTK
glycerate kinase
chr4_+_56436131 0.21 ENST00000399688.7
PAICS
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0042323 germinal center B cell differentiation(GO:0002314) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) xanthine metabolic process(GO:0046110) negative regulation of mucus secretion(GO:0070256)
0.6 1.7 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) regulation of skeletal muscle fiber differentiation(GO:1902809)
0.5 1.9 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.4 1.1 GO:0071373 cellular response to cocaine(GO:0071314) cellular response to luteinizing hormone stimulus(GO:0071373)
0.3 2.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.3 1.5 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.3 1.0 GO:0042369 vitamin D catabolic process(GO:0042369)
0.2 0.9 GO:0007538 primary sex determination(GO:0007538)
0.2 1.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.2 1.0 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.2 0.8 GO:0021634 optic nerve formation(GO:0021634) optic chiasma development(GO:0061360) regulation of optic nerve formation(GO:2000595) positive regulation of optic nerve formation(GO:2000597)
0.2 1.0 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.2 1.0 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.2 1.1 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.2 0.8 GO:0042851 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.2 0.5 GO:0043006 reduction of food intake in response to dietary excess(GO:0002023) activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1 0.9 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.1 0.6 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 3.5 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.4 GO:0042938 dipeptide transport(GO:0042938)
0.1 0.5 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.1 0.7 GO:0060356 leucine import(GO:0060356)
0.1 0.8 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.9 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.7 GO:2000669 positive regulation of pinocytosis(GO:0048549) negative regulation of dendritic cell apoptotic process(GO:2000669)
0.1 0.3 GO:0070895 transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895)
0.1 0.4 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.3 GO:1902869 regulation of amacrine cell differentiation(GO:1902869)
0.1 0.6 GO:0044375 peroxisome membrane biogenesis(GO:0016557) regulation of peroxisome size(GO:0044375)
0.1 0.7 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.1 1.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 0.2 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 1.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.3 GO:0042247 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.1 0.4 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.1 0.2 GO:2000174 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.1 0.2 GO:0060913 inner cell mass cellular morphogenesis(GO:0001828) cardiac cell fate determination(GO:0060913)
0.1 0.6 GO:0034036 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 0.5 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.2 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 0.9 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.3 GO:0007412 axon target recognition(GO:0007412)
0.1 0.2 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.1 0.6 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.5 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.2 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.0 0.4 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.7 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.2 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.3 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.8 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.2 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.5 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 1.4 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.3 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.4 GO:2000371 regulation of methylation-dependent chromatin silencing(GO:0090308) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.0 0.2 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.3 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.0 0.0 GO:0097694 establishment of RNA localization to telomere(GO:0097694) establishment of macromolecular complex localization to telomere(GO:0097695)
0.0 0.7 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.2 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.6 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.8 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.1 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.4 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 1.5 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0 0.2 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242)
0.0 0.5 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 1.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0046959 habituation(GO:0046959)
0.0 0.2 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.2 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.4 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 1.6 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.4 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.3 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.2 GO:0060613 fat pad development(GO:0060613)
0.0 0.5 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.3 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 1.1 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.5 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.6 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.1 GO:0007068 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 2.6 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 1.9 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 0.6 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.0 0.1 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0031017 exocrine pancreas development(GO:0031017)
0.0 0.1 GO:1903412 response to bile acid(GO:1903412)
0.0 0.1 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.2 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.5 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 1.4 GO:0021549 cerebellum development(GO:0021549)
0.0 0.7 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.2 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.6 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265) positive regulation of nuclease activity(GO:0032075) positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.4 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.2 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.0 GO:0051365 leading edge cell differentiation(GO:0035026) cellular response to potassium ion starvation(GO:0051365)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:1990742 microvesicle(GO:1990742)
0.3 1.9 GO:0005610 laminin-5 complex(GO:0005610)
0.2 1.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 1.6 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 3.5 GO:0005916 fascia adherens(GO:0005916)
0.1 0.8 GO:1990393 3M complex(GO:1990393)
0.1 1.1 GO:0001939 female pronucleus(GO:0001939) male pronucleus(GO:0001940)
0.1 0.5 GO:0045160 myosin I complex(GO:0045160)
0.1 0.3 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.1 0.5 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.4 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 2.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.3 GO:0042643 actomyosin, actin portion(GO:0042643)
0.1 0.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 1.2 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.2 GO:0031417 NatC complex(GO:0031417)
0.0 0.4 GO:0071439 clathrin complex(GO:0071439)
0.0 2.0 GO:0002102 podosome(GO:0002102)
0.0 0.7 GO:0033643 host cell part(GO:0033643)
0.0 0.8 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.5 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.5 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 1.4 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.2 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.8 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.6 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.6 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.3 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 1.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.2 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.8 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.4 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.6 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 2.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.6 1.7 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.4 1.5 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.3 1.0 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.3 1.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.3 0.8 GO:0047635 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.2 0.7 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.2 1.0 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.2 3.0 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 3.0 GO:0019864 IgG binding(GO:0019864)
0.1 0.4 GO:0004638 phosphoribosylaminoimidazole carboxylase activity(GO:0004638) phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 0.6 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.1 1.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.8 GO:0042806 fucose binding(GO:0042806)
0.1 3.5 GO:0017166 vinculin binding(GO:0017166)
0.1 0.5 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 0.3 GO:0001601 peptide YY receptor activity(GO:0001601)
0.1 2.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 2.5 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 0.4 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
0.1 0.9 GO:0043426 MRF binding(GO:0043426)
0.1 0.4 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.1 0.3 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 1.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.3 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.1 1.4 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.4 GO:0031493 nucleosomal histone binding(GO:0031493)
0.1 0.2 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.1 0.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.5 GO:0004673 phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673)
0.0 1.3 GO:0044548 S100 protein binding(GO:0044548)
0.0 1.7 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.8 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.4 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.4 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.8 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.7 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 1.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.4 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 1.4 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.5 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.3 GO:0051373 FATZ binding(GO:0051373)
0.0 0.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.1 GO:0097259 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.5 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.4 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.4 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 1.1 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.0 2.5 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 1.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 1.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.4 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.4 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.3 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 1.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 3.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.7 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 2.6 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.6 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.6 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.2 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.8 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.1 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.4 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 PID FOXO PATHWAY FoxO family signaling
0.0 0.7 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 3.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 2.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.9 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 1.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 3.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 2.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 1.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 2.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.4 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0 1.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.7 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 1.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.5 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC