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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for TGIF1

Z-value: 0.92

Motif logo

Transcription factors associated with TGIF1

Gene Symbol Gene ID Gene Info
ENSG00000177426.22 TGIF1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TGIF1hg38_v1_chr18_+_3449413_3449619-0.164.1e-01Click!

Activity profile of TGIF1 motif

Sorted Z-values of TGIF1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TGIF1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_153460644 2.69 ENST00000368723.4
S100 calcium binding protein A7
chr13_+_77535681 1.45 ENST00000349847.4
sciellin
chr13_+_77535742 1.44 ENST00000377246.7
sciellin
chr13_+_77535669 1.44 ENST00000535157.5
sciellin
chr1_+_153416517 1.41 ENST00000368729.9
S100 calcium binding protein A7A
chr7_-_23347704 1.38 ENST00000619562.4
insulin like growth factor 2 mRNA binding protein 3
chr2_+_33134620 1.34 ENST00000402934.5
ENST00000404525.5
ENST00000407925.5
latent transforming growth factor beta binding protein 1
chr4_+_68447453 1.31 ENST00000305363.9
transmembrane serine protease 11E
chr4_-_174522315 1.31 ENST00000514584.5
15-hydroxyprostaglandin dehydrogenase
chr4_+_8182066 1.28 ENST00000508641.2
SH3 domain and tetratricopeptide repeats 1
chr1_-_205455954 1.27 ENST00000495594.2
ENST00000629624.2
LEM domain containing 1
bladder cancer associated transcript 1
chr12_-_119804472 1.25 ENST00000678087.1
ENST00000677993.1
citron rho-interacting serine/threonine kinase
chr22_-_37244417 1.25 ENST00000405484.5
ENST00000441619.5
ENST00000406508.5
Rac family small GTPase 2
chr12_-_119804298 1.24 ENST00000678652.1
ENST00000678494.1
citron rho-interacting serine/threonine kinase
chr2_+_33134579 1.22 ENST00000418533.6
latent transforming growth factor beta binding protein 1
chr4_-_174522446 1.21 ENST00000296521.11
ENST00000296522.11
ENST00000422112.6
ENST00000504433.1
15-hydroxyprostaglandin dehydrogenase
chr14_-_24263162 1.17 ENST00000206765.11
ENST00000544573.5
transglutaminase 1
chr7_+_142770960 1.14 ENST00000632805.1
ENST00000633969.1
ENST00000539842.6
serine protease 2
chr22_-_37244237 1.12 ENST00000401529.3
ENST00000249071.11
Rac family small GTPase 2
chr2_+_238848029 1.11 ENST00000448943.2
ENST00000612363.2
twist family bHLH transcription factor 2
chr17_+_17042433 1.10 ENST00000651222.2
myosin phosphatase Rho interacting protein
chr3_-_127822455 1.10 ENST00000265052.10
monoglyceride lipase
chr4_-_174522791 1.08 ENST00000541923.5
ENST00000542498.5
15-hydroxyprostaglandin dehydrogenase
chr8_-_41665200 1.07 ENST00000335651.6
ankyrin 1
chr7_-_97872120 1.05 ENST00000394309.7
ENST00000414884.1
ENST00000442734.5
asparagine synthetase (glutamine-hydrolyzing)
chr3_-_127822835 1.03 ENST00000453507.6
monoglyceride lipase
chr10_-_96357155 1.03 ENST00000536387.5
oligodendrocytic myelin paranodal and inner loop protein
chr19_-_51034727 1.01 ENST00000525263.5
kallikrein related peptidase 12
chr1_-_24143112 0.95 ENST00000270800.2
interleukin 22 receptor subunit alpha 1
chr9_+_34652167 0.94 ENST00000441545.7
ENST00000553620.5
interleukin 11 receptor subunit alpha
chr19_-_51034840 0.94 ENST00000529888.5
kallikrein related peptidase 12
chr19_-_51034892 0.90 ENST00000319590.8
ENST00000250351.4
kallikrein related peptidase 12
chr1_+_156282917 0.90 ENST00000295694.9
ENST00000357501.6
transmembrane protein 79
chr17_+_4498866 0.89 ENST00000329078.8
sphingolipid transporter 2
chr16_+_69105636 0.88 ENST00000569188.6
hyaluronan synthase 3
chr1_-_151006404 0.85 ENST00000622754.4
MINDY lysine 48 deubiquitinase 1
chr3_-_127823235 0.84 ENST00000398104.5
monoglyceride lipase
chr9_+_72628020 0.83 ENST00000646619.1
transmembrane channel like 1
chr3_-_127823177 0.79 ENST00000434178.6
monoglyceride lipase
chr1_-_151006471 0.79 ENST00000493834.2
MINDY lysine 48 deubiquitinase 1
chr1_-_230978796 0.78 ENST00000522821.5
ENST00000366662.8
ENST00000366661.9
ENST00000522399.1
tetratricopeptide repeat domain 13
chr16_+_30183595 0.77 ENST00000219150.10
ENST00000570045.5
ENST00000565497.5
ENST00000570244.5
coronin 1A
chr6_+_24774925 0.76 ENST00000356509.7
ENST00000230056.8
geminin DNA replication inhibitor
chr19_-_49362376 0.76 ENST00000601519.5
ENST00000593945.6
ENST00000539846.5
ENST00000596757.1
ENST00000311227.6
TEA domain transcription factor 2
chr2_+_33436304 0.76 ENST00000402538.7
RAS guanyl releasing protein 3
chr1_-_151006795 0.75 ENST00000312210.9
ENST00000683666.1
MINDY lysine 48 deubiquitinase 1
chr5_-_128538230 0.75 ENST00000262464.9
fibrillin 2
chr2_+_233060295 0.75 ENST00000445964.6
inositol polyphosphate-5-phosphatase D
chr20_-_5610980 0.75 ENST00000379019.7
glycerophosphocholine phosphodiesterase 1
chr6_+_24775413 0.75 ENST00000378054.6
ENST00000620958.4
ENST00000476555.5
geminin DNA replication inhibitor
chr19_-_51034993 0.75 ENST00000684732.1
kallikrein related peptidase 12
chr19_+_44905785 0.74 ENST00000446996.5
ENST00000252486.9
ENST00000434152.5
apolipoprotein E
chr18_-_70205655 0.73 ENST00000255674.11
ENST00000640769.2
rotatin
chr21_+_29130630 0.72 ENST00000399926.5
ENST00000399928.6
MAP3K7 C-terminal like
chr2_+_227813834 0.72 ENST00000358813.5
ENST00000409189.7
C-C motif chemokine ligand 20
chr2_-_18589536 0.70 ENST00000416783.1
ENST00000359846.6
ENST00000304081.8
ENST00000532967.5
ENST00000444297.2
5'-nucleotidase, cytosolic IB
NT5C1B-RDH14 readthrough
chr11_-_107858777 0.70 ENST00000525815.6
solute carrier family 35 member F2
chr6_+_80004615 0.69 ENST00000369798.7
ENST00000502580.5
ENST00000511260.5
TTK protein kinase
chr17_-_41505597 0.68 ENST00000336861.7
ENST00000246635.8
ENST00000587544.5
ENST00000587435.1
keratin 13
chr2_+_135586250 0.67 ENST00000410054.5
ENST00000628915.2
R3H domain containing 1
chr22_-_50085414 0.67 ENST00000311597.10
modulator of VRAC current 1
chr1_-_186680411 0.66 ENST00000367468.10
prostaglandin-endoperoxide synthase 2
chr22_-_50085331 0.66 ENST00000395876.6
modulator of VRAC current 1
chr11_+_842807 0.65 ENST00000397411.6
tetraspanin 4
chr8_-_123396412 0.65 ENST00000287394.10
ATPase family AAA domain containing 2
chr12_+_15322257 0.63 ENST00000674316.1
protein tyrosine phosphatase receptor type O
chr2_+_184598520 0.63 ENST00000302277.7
zinc finger protein 804A
chr11_+_842824 0.62 ENST00000397396.5
ENST00000397397.7
tetraspanin 4
chr17_+_59155726 0.62 ENST00000578777.5
ENST00000577457.1
ENST00000582995.5
ENST00000262293.9
ENST00000614081.1
proline rich 11
chr21_-_34615103 0.62 ENST00000313806.9
regulator of calcineurin 1
chr9_+_34990250 0.61 ENST00000454002.6
ENST00000545841.5
DnaJ heat shock protein family (Hsp40) member B5
chr9_-_36276967 0.61 ENST00000396594.8
ENST00000543356.7
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr11_+_842928 0.61 ENST00000397408.5
tetraspanin 4
chr2_+_57907621 0.61 ENST00000648897.1
ENST00000435505.6
ENST00000417641.6
VRK serine/threonine kinase 2
chr9_+_121737151 0.60 ENST00000648444.1
DAB2 interacting protein
chr19_-_43465596 0.60 ENST00000244333.4
LY6/PLAUR domain containing 3
chr17_+_78214286 0.59 ENST00000592734.5
ENST00000587746.5
baculoviral IAP repeat containing 5
chr10_+_52314272 0.59 ENST00000373970.4
dickkopf WNT signaling pathway inhibitor 1
chr9_+_113444725 0.58 ENST00000374140.6
regulator of G protein signaling 3
chr12_+_15322529 0.58 ENST00000348962.7
protein tyrosine phosphatase receptor type O
chr17_-_7590072 0.58 ENST00000538513.6
ENST00000570788.1
ENST00000250055.3
SRY-box transcription factor 15
chr12_+_27332955 0.58 ENST00000311001.9
ENST00000261178.9
ENST00000266503.9
aryl hydrocarbon receptor nuclear translocator like 2
chr7_+_134866831 0.57 ENST00000435928.1
caldesmon 1
chr8_+_38386433 0.57 ENST00000297720.9
ENST00000524874.5
ENST00000379957.9
ENST00000523983.6
leucine zipper and EF-hand containing transmembrane protein 2
chr5_-_132777215 0.57 ENST00000458488.2
septin 8
chr19_-_45322867 0.57 ENST00000221476.4
creatine kinase, M-type
chr2_-_210315160 0.56 ENST00000352451.4
myosin light chain 1
chr17_-_59155235 0.56 ENST00000581068.5
spindle and kinetochore associated complex subunit 2
chr2_-_118847638 0.56 ENST00000295206.7
engrailed homeobox 1
chr22_-_29838227 0.56 ENST00000307790.8
ENST00000397771.6
ENST00000542393.5
activating signal cointegrator 1 complex subunit 2
chr17_-_35795592 0.55 ENST00000615136.4
ENST00000605424.6
ENST00000612672.1
matrix metallopeptidase 28
chr9_-_69672341 0.55 ENST00000265381.7
amyloid beta precursor protein binding family A member 1
chr19_-_43780957 0.55 ENST00000648319.1
potassium calcium-activated channel subfamily N member 4
chr12_+_101594849 0.53 ENST00000547405.5
ENST00000452455.6
ENST00000392934.7
ENST00000547509.5
ENST00000361685.6
ENST00000549145.5
ENST00000361466.7
ENST00000553190.5
ENST00000545503.6
ENST00000536007.5
ENST00000541119.5
ENST00000551300.5
ENST00000550270.1
myosin binding protein C1
chr8_+_31639291 0.53 ENST00000651149.1
ENST00000650866.1
neuregulin 1
chr8_+_31639222 0.53 ENST00000519301.6
ENST00000652698.1
neuregulin 1
chr9_+_122371036 0.53 ENST00000619306.5
ENST00000426608.6
ENST00000223423.8
prostaglandin-endoperoxide synthase 1
chr20_+_2295994 0.52 ENST00000381458.6
transglutaminase 3
chr10_-_3785197 0.52 ENST00000497571.6
Kruppel like factor 6
chr22_+_46296850 0.51 ENST00000454366.2
G2 and S-phase expressed 1
chr19_-_43781249 0.51 ENST00000615047.4
potassium calcium-activated channel subfamily N member 4
chr1_+_74235377 0.51 ENST00000326637.8
TNNI3 interacting kinase
chr7_-_108130349 0.51 ENST00000205386.8
ENST00000418464.1
ENST00000388781.8
laminin subunit beta 4
chr14_-_63728027 0.51 ENST00000247225.7
sphingosine-1-phosphate phosphatase 1
chrX_+_102125668 0.50 ENST00000372780.6
transcription elongation factor A like 2
chrX_+_102125703 0.50 ENST00000329035.2
transcription elongation factor A like 2
chr10_+_68988767 0.48 ENST00000626493.2
ENST00000638119.2
ENST00000674936.1
ENST00000674660.1
ENST00000675576.1
ENST00000361983.7
ENST00000635971.2
kinesin family binding protein
chr12_+_106684696 0.48 ENST00000229387.6
regulatory factor X4
chr12_+_55932028 0.48 ENST00000394147.5
ENST00000551156.5
ENST00000553783.5
ENST00000557080.5
ENST00000432422.7
ENST00000556001.5
diacylglycerol kinase alpha
chr8_+_11809135 0.48 ENST00000528643.5
ENST00000525777.5
farnesyl-diphosphate farnesyltransferase 1
chr1_+_156284299 0.47 ENST00000456810.1
ENST00000405535.3
transmembrane protein 79
chr7_+_151114597 0.47 ENST00000335367.7
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr1_-_11848345 0.46 ENST00000376476.1
natriuretic peptide A
chr4_+_87975829 0.45 ENST00000614857.5
secreted phosphoprotein 1
chr17_+_44846318 0.45 ENST00000591513.5
HIG1 hypoxia inducible domain family member 1B
chr12_+_56021316 0.45 ENST00000547791.2
IKAROS family zinc finger 4
chr11_+_129375841 0.45 ENST00000281437.6
BARX homeobox 2
chr4_+_87975667 0.44 ENST00000237623.11
ENST00000682655.1
ENST00000508233.6
ENST00000360804.4
ENST00000395080.8
secreted phosphoprotein 1
chr14_-_100376251 0.44 ENST00000556645.5
ENST00000556209.5
ENST00000556504.5
ENST00000556435.5
ENST00000554772.5
ENST00000553581.1
ENST00000553769.6
ENST00000554605.5
ENST00000557722.5
ENST00000553413.5
ENST00000553524.5
ENST00000358655.8
tryptophanyl-tRNA synthetase 1
chr11_-_111923722 0.44 ENST00000527950.5
crystallin alpha B
chr1_-_169630115 0.44 ENST00000263686.11
ENST00000367788.6
selectin P
chr8_-_48921419 0.44 ENST00000020945.4
snail family transcriptional repressor 2
chr5_-_88877967 0.43 ENST00000508610.5
ENST00000636294.1
myocyte enhancer factor 2C
chr11_-_128587551 0.43 ENST00000392668.8
ETS proto-oncogene 1, transcription factor
chr15_+_59105099 0.43 ENST00000288207.7
ENST00000559622.5
cyclin B2
chr20_+_1266263 0.42 ENST00000649598.1
ENST00000381867.6
ENST00000381873.7
syntaphilin
chr17_-_40867200 0.42 ENST00000647902.1
ENST00000251643.5
keratin 12
chr13_+_27919993 0.42 ENST00000381033.5
pancreatic and duodenal homeobox 1
chr1_-_152115443 0.42 ENST00000614923.1
trichohyalin
chr15_-_29822418 0.41 ENST00000614355.5
ENST00000495972.6
ENST00000346128.10
tight junction protein 1
chr12_+_62260374 0.41 ENST00000312635.10
ENST00000280377.10
ENST00000549237.5
ubiquitin specific peptidase 15
chr17_+_76738012 0.41 ENST00000590514.5
major facilitator superfamily domain containing 11
chr15_+_75206398 0.41 ENST00000565074.1
chromosome 15 open reading frame 39
chr6_+_41053194 0.40 ENST00000244669.3
apolipoprotein B mRNA editing enzyme catalytic subunit 2
chr11_-_111910888 0.39 ENST00000525823.1
ENST00000528961.6
crystallin alpha B
chr18_+_56651385 0.39 ENST00000615645.4
WD repeat domain 7
chr15_-_55270280 0.39 ENST00000564609.5
RAB27A, member RAS oncogene family
chr5_+_115962467 0.39 ENST00000357872.9
ENST00000395528.6
laeverin
chr8_-_92017637 0.38 ENST00000422361.6
RUNX1 partner transcriptional co-repressor 1
chr17_+_4948252 0.38 ENST00000520221.5
enolase 3
chr9_+_136945234 0.38 ENST00000371634.7
complement C8 gamma chain
chr4_+_76949807 0.38 ENST00000505788.5
ENST00000510515.5
ENST00000504637.5
septin 11
chr1_+_243256034 0.38 ENST00000366541.8
SHH signaling and ciliogenesis regulator SDCCAG8
chr20_+_833705 0.38 ENST00000381941.8
family with sequence similarity 110 member A
chr14_-_99271485 0.38 ENST00000345514.2
ENST00000443726.2
BAF chromatin remodeling complex subunit BCL11B
chr9_+_706841 0.38 ENST00000382293.7
KN motif and ankyrin repeat domains 1
chr11_-_111910830 0.38 ENST00000526167.5
ENST00000651650.1
crystallin alpha B
chr5_-_179620933 0.38 ENST00000521173.5
heterogeneous nuclear ribonucleoprotein H1
chr5_-_132777344 0.38 ENST00000378706.5
septin 8
chr7_-_148883474 0.38 ENST00000476773.5
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr19_-_48044037 0.37 ENST00000293255.3
calcium binding protein 5
chr3_-_33645253 0.37 ENST00000333778.10
cytoplasmic linker associated protein 2
chr16_+_31033092 0.37 ENST00000394998.5
syntaxin 4
chr1_+_230067198 0.37 ENST00000366672.5
polypeptide N-acetylgalactosaminyltransferase 2
chr20_+_833781 0.36 ENST00000381939.1
family with sequence similarity 110 member A
chr5_+_150508110 0.36 ENST00000261797.7
N-deacetylase and N-sulfotransferase 1
chr3_+_111859284 0.36 ENST00000498699.5
pleckstrin homology like domain family B member 2
chr2_+_27496830 0.36 ENST00000264717.7
glucokinase regulator
chr12_+_77830886 0.36 ENST00000397909.7
ENST00000549464.5
neuron navigator 3
chr6_-_10414985 0.35 ENST00000466073.5
ENST00000498450.3
transcription factor AP-2 alpha
chrX_+_41688967 0.35 ENST00000378142.9
G protein-coupled receptor 34
chr9_+_122370523 0.35 ENST00000643810.1
ENST00000540753.6
prostaglandin-endoperoxide synthase 1
chr1_-_193106048 0.35 ENST00000367440.3
glutaredoxin 2
chrX_+_41689006 0.35 ENST00000378138.5
ENST00000620846.1
ENST00000649219.1
G protein-coupled receptor 34
chr1_+_101237009 0.35 ENST00000305352.7
sphingosine-1-phosphate receptor 1
chr3_+_111859180 0.34 ENST00000412622.5
ENST00000431670.7
pleckstrin homology like domain family B member 2
chr3_-_190122317 0.34 ENST00000427335.6
prolyl 3-hydroxylase 2
chr4_+_54229261 0.34 ENST00000508170.5
ENST00000512143.1
ENST00000257290.10
platelet derived growth factor receptor alpha
chrX_+_71283186 0.34 ENST00000535149.5
non-POU domain containing octamer binding
chr10_+_119726118 0.34 ENST00000369081.3
ENST00000648262.1
inositol polyphosphate-5-phosphatase F
chrX_+_136205982 0.34 ENST00000628568.1
four and a half LIM domains 1
chr14_+_21317535 0.34 ENST00000382933.8
RPGR interacting protein 1
chr5_-_160370619 0.33 ENST00000652664.2
ENST00000393975.4
C1q and TNF related 2
chr1_+_36156096 0.33 ENST00000474796.2
ENST00000373150.8
ENST00000373151.6
MAP7 domain containing 1
chr15_-_55270383 0.33 ENST00000396307.6
RAB27A, member RAS oncogene family
chr15_+_32717994 0.33 ENST00000560677.5
ENST00000560830.1
ENST00000651154.1
gremlin 1, DAN family BMP antagonist
chr10_-_14330879 0.32 ENST00000357447.7
FERM domain containing 4A
chr16_+_69424634 0.32 ENST00000515314.6
ENST00000561792.6
ENST00000568237.1
cytochrome b5 type B
chr1_-_208244375 0.32 ENST00000367033.4
plexin A2
chr12_+_12891554 0.32 ENST00000014914.6
G protein-coupled receptor class C group 5 member A
chr7_+_77840122 0.32 ENST00000450574.5
ENST00000248550.7
putative homeodomain transcription factor 2
chr3_-_33645433 0.32 ENST00000635664.1
ENST00000485378.6
ENST00000313350.10
ENST00000487200.5
cytoplasmic linker associated protein 2
chr12_+_62260338 0.31 ENST00000353364.7
ENST00000549523.5
ubiquitin specific peptidase 15
chr14_+_21057822 0.31 ENST00000308227.2
ribonuclease A family member 8
chr16_+_88570387 0.31 ENST00000452588.6
ENST00000301011.10
zinc finger CCCH-type containing 18
chr11_-_123885627 0.31 ENST00000528595.1
ENST00000375026.7
transmembrane protein 225
chr11_-_78417788 0.31 ENST00000361507.5
GRB2 associated binding protein 2
chr1_-_11058839 0.31 ENST00000465788.1
spermidine synthase
chr19_+_48469354 0.31 ENST00000452733.7
ENST00000641098.1
cytohesin 2
chr2_-_196926717 0.30 ENST00000409475.5
ENST00000374738.3
post-GPI attachment to proteins inositol deacylase 1
chr1_-_33431079 0.30 ENST00000683057.1
polyhomeotic homolog 2
chr10_-_77638369 0.30 ENST00000372443.6
potassium calcium-activated channel subfamily M alpha 1
chr16_-_2980406 0.30 ENST00000431515.6
ENST00000574385.5
ENST00000576268.1
ENST00000574730.5
ENST00000262300.13
ENST00000575632.5
ENST00000573944.5
protein kinase, membrane associated tyrosine/threonine 1
chr10_-_3785179 0.30 ENST00000469435.1
Kruppel like factor 6
chr8_+_38386303 0.30 ENST00000519476.6
leucine zipper and EF-hand containing transmembrane protein 2
chr1_+_26432803 0.30 ENST00000430232.5
dehydrodolichyl diphosphate synthase subunit
chr20_-_32536383 0.30 ENST00000375678.7
nucleolar protein 4 like
chr12_+_4538830 0.29 ENST00000228843.13
ENST00000352618.9
ENST00000544927.5
RAD51 associated protein 1
chr3_-_49029378 0.29 ENST00000442157.2
ENST00000326739.9
ENST00000677010.1
ENST00000678724.1
ENST00000429182.6
inosine monophosphate dehydrogenase 2
chr17_-_40999903 0.29 ENST00000391587.3
keratin associated protein 3-2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.6 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.4 3.8 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.4 1.4 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.3 1.4 GO:0042335 cuticle development(GO:0042335)
0.3 1.5 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.3 3.6 GO:2001300 ductus arteriosus closure(GO:0097070) lipoxin metabolic process(GO:2001300)
0.3 1.1 GO:0070982 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
0.2 0.7 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.2 0.7 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.2 0.7 GO:1901994 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.2 2.7 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.2 0.9 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.2 0.9 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.2 0.9 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.2 0.7 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.2 2.4 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.2 0.6 GO:0006045 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.2 0.6 GO:1901228 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.2 0.2 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.2 0.6 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.2 0.6 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.2 0.8 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2 0.6 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.2 0.3 GO:0038086 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.2 0.6 GO:0003409 optic cup structural organization(GO:0003409)
0.1 0.4 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.1 0.6 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1 0.4 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.5 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.1 0.8 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.1 0.4 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.1 0.4 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.1 0.8 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.1 0.4 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.1 0.5 GO:0070378 positive regulation of ERK5 cascade(GO:0070378)
0.1 0.7 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.4 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.1 0.3 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.1 0.6 GO:0061743 motor learning(GO:0061743)
0.1 0.4 GO:0010157 response to chlorate(GO:0010157)
0.1 0.5 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.1 0.6 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.1 1.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.3 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 0.7 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.4 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.4 GO:1902568 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 0.4 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.1 0.8 GO:0060005 vestibular reflex(GO:0060005)
0.1 1.2 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.1 1.1 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.5 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 1.3 GO:0071397 cellular response to cholesterol(GO:0071397)
0.1 0.3 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 0.5 GO:1904526 regulation of microtubule binding(GO:1904526)
0.1 1.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.6 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.3 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 1.2 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.5 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1 0.6 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.3 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.4 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.2 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 0.2 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.1 0.4 GO:0015798 myo-inositol transport(GO:0015798)
0.1 1.0 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.7 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.2 GO:0018879 biphenyl metabolic process(GO:0018879)
0.0 1.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.7 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.3 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.4 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.2 GO:1990535 neuron projection maintenance(GO:1990535)
0.0 0.3 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.0 0.6 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.6 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.3 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 0.1 GO:0061580 colon epithelial cell migration(GO:0061580)
0.0 0.2 GO:1990523 bone regeneration(GO:1990523)
0.0 0.8 GO:0030903 notochord development(GO:0030903)
0.0 2.5 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.4 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.4 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.0 0.4 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.2 GO:0021612 facial nerve structural organization(GO:0021612)
0.0 5.1 GO:0070268 cornification(GO:0070268)
0.0 0.6 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.0 0.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.5 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.3 GO:0051126 negative regulation of actin nucleation(GO:0051126)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.7 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 0.6 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.3 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.0 0.2 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 0.3 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.6 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.1 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:2000987 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.0 0.5 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.3 GO:0042262 DNA protection(GO:0042262)
0.0 0.4 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.5 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.2 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.0 0.1 GO:0097069 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.0 0.2 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.5 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 1.0 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:2000851 positive regulation of glucocorticoid secretion(GO:2000851)
0.0 0.2 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.1 GO:0030002 cellular anion homeostasis(GO:0030002) cellular monovalent inorganic anion homeostasis(GO:0030320) cellular chloride ion homeostasis(GO:0030644)
0.0 0.2 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.3 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 1.2 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.5 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.2 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0014873 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.2 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.6 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.1 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.3 GO:0045176 apical protein localization(GO:0045176)
0.0 0.3 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 3.0 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.1 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.2 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.3 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.2 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.1 GO:0002118 aggressive behavior(GO:0002118)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.6 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.2 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 0.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.2 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.2 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.1 GO:0090170 trachea formation(GO:0060440) regulation of Golgi inheritance(GO:0090170)
0.0 0.3 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.0 0.3 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 1.2 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.2 GO:0043586 tongue development(GO:0043586)
0.0 0.9 GO:0007566 embryo implantation(GO:0007566)
0.0 0.2 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.5 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.0 1.0 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 1.2 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 0.5 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:0050765 mitochondrial fragmentation involved in apoptotic process(GO:0043653) negative regulation of phagocytosis(GO:0050765)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.1 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.0 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.2 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0036117 hyaluranon cable(GO:0036117)
0.2 0.8 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.2 3.6 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.2 0.6 GO:1990032 parallel fiber(GO:1990032)
0.1 0.5 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 5.7 GO:0001533 cornified envelope(GO:0001533)
0.1 1.4 GO:0045180 basal cortex(GO:0045180)
0.1 1.2 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.2 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.6 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.7 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 2.8 GO:0030673 axolemma(GO:0030673)
0.0 0.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.7 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.8 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.6 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.4 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0001652 granular component(GO:0001652)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.4 GO:0000322 storage vacuole(GO:0000322)
0.0 0.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 1.2 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.2 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 3.8 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.2 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 2.6 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.4 GO:0045120 pronucleus(GO:0045120)
0.0 0.8 GO:0042629 mast cell granule(GO:0042629)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.3 GO:0005915 zonula adherens(GO:0005915)
0.0 2.6 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.1 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.7 GO:0005921 gap junction(GO:0005921)
0.0 0.3 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 2.0 GO:0005901 caveola(GO:0005901)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.3 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.8 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.0 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.6 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.6 2.8 GO:0050436 microfibril binding(GO:0050436)
0.4 2.4 GO:0016807 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.3 1.7 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.3 0.8 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.2 0.7 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.2 1.1 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.2 1.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 0.9 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 3.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 0.9 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.2 0.9 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.7 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 2.7 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.8 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.5 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.1 0.7 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.6 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 1.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.3 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 1.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.3 GO:0004766 spermidine synthase activity(GO:0004766)
0.1 0.3 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.1 0.5 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.1 0.4 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.4 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 1.7 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.3 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.1 0.5 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 0.5 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.4 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.3 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.5 GO:0031013 troponin I binding(GO:0031013)
0.1 0.4 GO:0043208 fucose binding(GO:0042806) glycosphingolipid binding(GO:0043208)
0.1 0.6 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.2 GO:0019777 Atg12 transferase activity(GO:0019777)
0.1 0.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.5 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.8 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.3 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.2 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.0 0.3 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.4 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 1.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.3 GO:0030614 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.0 0.4 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.0 0.2 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.6 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 1.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.8 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.2 GO:1903135 cupric ion binding(GO:1903135)
0.0 1.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.5 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.6 GO:0019841 retinol binding(GO:0019841)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 1.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.7 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.8 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.4 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.7 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.7 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.5 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.6 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 0.5 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 1.0 GO:0050699 WW domain binding(GO:0050699)
0.0 5.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 1.3 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 1.3 GO:0043621 protein self-association(GO:0043621)
0.0 1.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 1.6 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.2 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 1.5 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.0 GO:0080101 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.0 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 1.9 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.5 GO:0051428 peptide hormone receptor binding(GO:0051428)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.5 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.5 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.1 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.3 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.4 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 2.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 3.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.5 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 2.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.1 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.7 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 1.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.7 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 1.1 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.6 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.7 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.1 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.2 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.8 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.5 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.6 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.7 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins