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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for THRA_RXRB

Z-value: 0.81

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Transcription factors associated with THRA_RXRB

Gene Symbol Gene ID Gene Info
THRA
ENSG00000126351.13 THRA
RXRB
ENSG00000204231.11 RXRB

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
THRAhg38_v1_chr17_+_40062810_40062901-0.613.6e-04Click!
RXRBhg38_v1_chr6_-_33200614_33200680-0.487.5e-03Click!

Activity profile of THRA_RXRB motif

Sorted Z-values of THRA_RXRB motif

Network of associatons between targets according to the STRING database.

First level regulatory network of THRA_RXRB

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_+_152908538 3.44 ENST00000368764.4
IVL
involucrin
chr5_+_163460623 2.54 ENST00000393915.9
ENST00000432118.6
HMMR
hyaluronan mediated motility receptor
chr10_+_11742361 2.30 ENST00000379215.9
ENST00000420401.5
ECHDC3
enoyl-CoA hydratase domain containing 3
chr19_-_51065067 2.21 ENST00000595547.5
ENST00000335422.3
ENST00000595793.6
ENST00000596955.1
KLK13
kallikrein related peptidase 13
chr1_+_150549734 2.16 ENST00000674043.1
ENST00000674058.1
ADAMTSL4
ADAMTS like 4
chr19_+_53867874 2.09 ENST00000448420.5
ENST00000439000.5
ENST00000391771.1
ENST00000391770.9
MYADM
myeloid associated differentiation marker
chr1_-_150720842 1.98 ENST00000442853.5
ENST00000368995.8
ENST00000322343.11
ENST00000361824.7
HORMAD1
HORMA domain containing 1
chr22_+_22922594 1.95 ENST00000390331.3
IGLC7
immunoglobulin lambda constant 7
chr9_+_122371036 1.93 ENST00000619306.5
ENST00000426608.6
ENST00000223423.8
PTGS1
prostaglandin-endoperoxide synthase 1
chr15_-_34337719 1.93 ENST00000559484.1
ENST00000558589.5
ENST00000458406.6
SLC12A6
solute carrier family 12 member 6
chr15_-_34338033 1.78 ENST00000558667.5
ENST00000561120.5
ENST00000559236.5
ENST00000397702.6
SLC12A6
solute carrier family 12 member 6
chr3_-_50303565 1.64 ENST00000266031.8
ENST00000395143.6
ENST00000457214.6
ENST00000447605.2
ENST00000395144.7
ENST00000418723.1
HYAL1
hyaluronidase 1
chr15_-_34337772 1.63 ENST00000354181.8
SLC12A6
solute carrier family 12 member 6
chr1_+_44746401 1.58 ENST00000372217.5
KIF2C
kinesin family member 2C
chr12_-_95116967 1.52 ENST00000551521.5
FGD6
FYVE, RhoGEF and PH domain containing 6
chr22_-_37188281 1.46 ENST00000397110.6
C1QTNF6
C1q and TNF related 6
chr19_+_6739650 1.44 ENST00000313285.12
ENST00000313244.14
ENST00000596758.5
TRIP10
thyroid hormone receptor interactor 10
chr1_+_17205119 1.42 ENST00000375471.5
PADI1
peptidyl arginine deiminase 1
chr5_+_148312416 1.40 ENST00000274565.5
SPINK7
serine peptidase inhibitor Kazal type 7
chr19_+_16076485 1.36 ENST00000643579.2
ENST00000646575.1
TPM4
tropomyosin 4
chr19_+_44777860 1.35 ENST00000341505.4
ENST00000647358.2
CBLC
Cbl proto-oncogene C
chr19_-_51723968 1.33 ENST00000222115.5
ENST00000540069.7
HAS1
hyaluronan synthase 1
chr3_+_12287859 1.32 ENST00000309576.11
ENST00000397015.7
PPARG
peroxisome proliferator activated receptor gamma
chr9_+_113536497 1.30 ENST00000462143.5
RGS3
regulator of G protein signaling 3
chr2_-_191151568 1.27 ENST00000358470.8
ENST00000432798.1
ENST00000450994.1
STAT4
signal transducer and activator of transcription 4
chr3_+_10026409 1.27 ENST00000287647.7
ENST00000676013.1
ENST00000675286.1
ENST00000419585.5
FANCD2
FA complementation group D2
chr3_+_12287962 1.25 ENST00000643197.2
ENST00000644622.2
PPARG
peroxisome proliferator activated receptor gamma
chr3_+_12288838 1.25 ENST00000455517.6
ENST00000681982.1
PPARG
peroxisome proliferator activated receptor gamma
chr3_+_12287899 1.23 ENST00000643888.2
PPARG
peroxisome proliferator activated receptor gamma
chr22_-_28741783 1.23 ENST00000439200.5
ENST00000405598.5
ENST00000398017.3
ENST00000649563.1
ENST00000650281.1
ENST00000425190.7
ENST00000404276.6
ENST00000650233.1
ENST00000348295.7
ENST00000382580.6
CHEK2
checkpoint kinase 2
chr20_+_44715360 1.21 ENST00000190983.5
CCN5
cellular communication network factor 5
chr3_+_12289061 1.17 ENST00000652522.1
ENST00000652431.1
ENST00000652098.1
ENST00000651735.1
ENST00000397026.7
PPARG
peroxisome proliferator activated receptor gamma
chr12_+_119178920 1.17 ENST00000281938.7
HSPB8
heat shock protein family B (small) member 8
chr4_-_110198579 1.13 ENST00000302274.8
ELOVL6
ELOVL fatty acid elongase 6
chr4_-_110198650 1.12 ENST00000394607.7
ELOVL6
ELOVL fatty acid elongase 6
chr12_+_119178953 1.12 ENST00000674542.1
HSPB8
heat shock protein family B (small) member 8
chr10_-_96357155 1.08 ENST00000536387.5
OPALIN
oligodendrocytic myelin paranodal and inner loop protein
chr1_-_175192911 1.07 ENST00000444639.5
KIAA0040
KIAA0040
chr3_-_197298558 1.02 ENST00000656944.1
ENST00000346964.6
ENST00000448528.6
ENST00000655488.1
ENST00000357674.9
ENST00000667157.1
ENST00000661336.1
ENST00000654737.1
ENST00000659716.1
ENST00000657381.1
DLG1
discs large MAGUK scaffold protein 1
chr17_-_29176752 1.00 ENST00000533112.5
MYO18A
myosin XVIIIA
chr8_-_143568854 1.00 ENST00000524906.5
ENST00000532862.1
ENST00000534459.5
MROH6
maestro heat like repeat family member 6
chrX_+_136148440 0.99 ENST00000627383.2
ENST00000630084.2
FHL1
four and a half LIM domains 1
chr20_+_3796288 0.98 ENST00000439880.6
ENST00000245960.10
CDC25B
cell division cycle 25B
chr11_-_58575846 0.97 ENST00000395074.7
LPXN
leupaxin
chr9_+_36572854 0.96 ENST00000543751.5
ENST00000536860.5
ENST00000541717.4
ENST00000536329.5
ENST00000536987.5
ENST00000298048.7
ENST00000495529.5
ENST00000545008.5
MELK
maternal embryonic leucine zipper kinase
chr1_-_175192769 0.91 ENST00000423313.6
KIAA0040
KIAA0040
chr22_-_37188233 0.90 ENST00000434784.1
ENST00000337843.7
C1QTNF6
C1q and TNF related 6
chr5_-_132227808 0.79 ENST00000401867.5
ENST00000379086.5
ENST00000379100.7
ENST00000418055.5
ENST00000453286.5
ENST00000360568.8
ENST00000379104.7
ENST00000166534.8
P4HA2
prolyl 4-hydroxylase subunit alpha 2
chr12_+_102120240 0.78 ENST00000537257.5
ENST00000392911.6
PARPBP
PARP1 binding protein
chr22_-_21227637 0.76 ENST00000401924.5
GGT2
gamma-glutamyltransferase 2
chr11_-_123885627 0.76 ENST00000528595.1
ENST00000375026.7
TMEM225
transmembrane protein 225
chr21_-_31558977 0.75 ENST00000286827.7
ENST00000541036.5
TIAM1
TIAM Rac1 associated GEF 1
chr12_+_102120172 0.75 ENST00000327680.7
ENST00000541394.5
ENST00000543784.5
PARPBP
PARP1 binding protein
chr17_-_5234801 0.73 ENST00000571800.5
ENST00000574081.6
ENST00000399600.8
ENST00000574297.1
SCIMP
SLP adaptor and CSK interacting membrane protein
chr22_+_22900976 0.73 ENST00000390323.2
IGLC2
immunoglobulin lambda constant 2
chr1_+_155613221 0.73 ENST00000462250.2
MSTO1
misato mitochondrial distribution and morphology regulator 1
chr16_+_67666770 0.71 ENST00000403458.9
ENST00000602365.1
C16orf86
chromosome 16 open reading frame 86
chr2_+_209653171 0.70 ENST00000447185.5
MAP2
microtubule associated protein 2
chr1_-_159925496 0.69 ENST00000368097.9
TAGLN2
transgelin 2
chr19_-_40690629 0.69 ENST00000252891.8
NUMBL
NUMB like endocytic adaptor protein
chr5_-_132227472 0.68 ENST00000428369.6
P4HA2
prolyl 4-hydroxylase subunit alpha 2
chr6_+_35805347 0.64 ENST00000360215.3
LHFPL5
LHFPL tetraspan subfamily member 5
chr15_-_34337462 0.64 ENST00000676379.1
SLC12A6
solute carrier family 12 member 6
chr22_-_37484505 0.63 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr1_+_150982268 0.63 ENST00000368947.9
ANXA9
annexin A9
chr2_+_218607861 0.62 ENST00000450993.7
PLCD4
phospholipase C delta 4
chr16_-_58295019 0.61 ENST00000567164.6
ENST00000219301.8
ENST00000569727.1
PRSS54
serine protease 54
chr1_-_6393750 0.60 ENST00000545482.5
ENST00000361521.9
ACOT7
acyl-CoA thioesterase 7
chr16_-_58294976 0.59 ENST00000543437.5
ENST00000569079.1
PRSS54
serine protease 54
chr1_+_70411180 0.58 ENST00000411986.6
CTH
cystathionine gamma-lyase
chrX_+_102125703 0.58 ENST00000329035.2
TCEAL2
transcription elongation factor A like 2
chrX_+_102125668 0.58 ENST00000372780.6
TCEAL2
transcription elongation factor A like 2
chr12_+_78863962 0.57 ENST00000393240.7
SYT1
synaptotagmin 1
chr14_-_105601728 0.55 ENST00000641420.1
ENST00000390541.2
IGHE
immunoglobulin heavy constant epsilon
chr7_+_2244476 0.53 ENST00000397049.2
NUDT1
nudix hydrolase 1
chr1_+_70411241 0.53 ENST00000370938.8
ENST00000346806.2
CTH
cystathionine gamma-lyase
chr1_+_154327737 0.53 ENST00000672630.1
ATP8B2
ATPase phospholipid transporting 8B2
chr22_+_18529810 0.52 ENST00000613597.1
TMEM191B
transmembrane protein 191B
chr2_+_130182224 0.52 ENST00000651060.1
ENST00000409255.1
ENST00000281871.11
ENST00000455239.1
MZT2B
mitotic spindle organizing protein 2B
chr4_-_1856090 0.51 ENST00000302787.3
LETM1
leucine zipper and EF-hand containing transmembrane protein 1
chr1_-_6393339 0.51 ENST00000608083.5
ACOT7
acyl-CoA thioesterase 7
chr10_-_114404480 0.51 ENST00000419268.1
ENST00000304129.9
AFAP1L2
actin filament associated protein 1 like 2
chr17_-_41060109 0.50 ENST00000391418.3
KRTAP2-3
keratin associated protein 2-3
chr15_-_45129857 0.50 ENST00000267803.8
ENST00000613425.4
ENST00000559014.5
ENST00000558851.1
ENST00000559988.5
ENST00000558996.5
ENST00000558422.5
ENST00000559226.5
ENST00000560572.6
ENST00000558326.5
ENST00000558377.5
ENST00000559644.5
DUOXA1
dual oxidase maturation factor 1
chr1_-_243843164 0.49 ENST00000491219.6
ENST00000680056.1
ENST00000492957.2
AKT3
AKT serine/threonine kinase 3
chr9_-_111036207 0.49 ENST00000541779.5
LPAR1
lysophosphatidic acid receptor 1
chr10_-_114404756 0.49 ENST00000369271.7
AFAP1L2
actin filament associated protein 1 like 2
chr1_+_24745396 0.49 ENST00000374379.9
CLIC4
chloride intracellular channel 4
chr1_-_205935822 0.48 ENST00000340781.8
SLC26A9
solute carrier family 26 member 9
chr8_+_27774566 0.48 ENST00000519637.1
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr10_-_75099489 0.47 ENST00000472493.6
ENST00000478873.7
ENST00000605915.5
DUSP13
dual specificity phosphatase 13
chrX_-_132961390 0.46 ENST00000370836.6
ENST00000521489.5
HS6ST2
heparan sulfate 6-O-sulfotransferase 2
chr20_+_63861498 0.46 ENST00000369916.5
ABHD16B
abhydrolase domain containing 16B
chr17_+_39738317 0.45 ENST00000394211.7
GRB7
growth factor receptor bound protein 7
chr22_-_23974441 0.45 ENST00000398344.9
ENST00000403754.7
ENST00000430101.2
DDT
D-dopachrome tautomerase
chr5_+_136058849 0.44 ENST00000508076.5
TGFBI
transforming growth factor beta induced
chr13_+_75549477 0.43 ENST00000618773.4
UCHL3
ubiquitin C-terminal hydrolase L3
chr10_+_26697653 0.43 ENST00000376215.10
PDSS1
decaprenyl diphosphate synthase subunit 1
chr14_-_105708627 0.43 ENST00000641837.1
ENST00000390547.3
IGHA1
immunoglobulin heavy constant alpha 1
chr18_+_63476927 0.43 ENST00000489441.5
ENST00000382771.9
ENST00000424602.1
SERPINB5
serpin family B member 5
chr17_-_1492660 0.43 ENST00000648651.1
MYO1C
myosin IC
chr17_+_39737923 0.43 ENST00000577695.5
ENST00000309156.9
GRB7
growth factor receptor bound protein 7
chr17_-_60392333 0.42 ENST00000590133.5
USP32
ubiquitin specific peptidase 32
chr21_+_37367097 0.42 ENST00000644942.1
DYRK1A
dual specificity tyrosine phosphorylation regulated kinase 1A
chr16_-_72172135 0.41 ENST00000537465.5
ENST00000237353.15
PMFBP1
polyamine modulated factor 1 binding protein 1
chr9_+_27109135 0.40 ENST00000519097.5
ENST00000615002.4
TEK
TEK receptor tyrosine kinase
chr2_-_164842011 0.40 ENST00000409184.8
ENST00000456693.5
COBLL1
cordon-bleu WH2 repeat protein like 1
chr2_-_65366650 0.40 ENST00000443619.6
SPRED2
sprouty related EVH1 domain containing 2
chr2_-_74440484 0.40 ENST00000305557.9
ENST00000233330.6
RTKN
rhotekin
chr17_-_42979993 0.39 ENST00000409103.5
ENST00000360221.8
ENST00000454303.1
ENST00000591916.7
ENST00000451885.3
PTGES3L-AARSD1
PTGES3L
PTGES3L-AARSD1 readthrough
prostaglandin E synthase 3 like
chr7_-_151736304 0.39 ENST00000492843.6
PRKAG2
protein kinase AMP-activated non-catalytic subunit gamma 2
chr4_+_168921555 0.39 ENST00000503290.1
PALLD
palladin, cytoskeletal associated protein
chr17_-_42980393 0.38 ENST00000409446.8
ENST00000409399.6
ENST00000421990.7
PTGES3L
PTGES3L-AARSD1
prostaglandin E synthase 3 like
PTGES3L-AARSD1 readthrough
chr11_+_55811367 0.38 ENST00000625203.2
OR5L1
olfactory receptor family 5 subfamily L member 1
chr9_+_27109200 0.38 ENST00000380036.10
TEK
TEK receptor tyrosine kinase
chr17_-_41055211 0.38 ENST00000542910.1
ENST00000398477.1
KRTAP2-2
keratin associated protein 2-2
chr22_-_38302990 0.38 ENST00000612795.2
ENST00000451964.5
CSNK1E
casein kinase 1 epsilon
chr12_+_57583101 0.38 ENST00000674858.1
ENST00000675433.1
ENST00000674980.1
KIF5A
kinesin family member 5A
chr12_-_102120065 0.38 ENST00000552283.6
ENST00000551744.2
NUP37
nucleoporin 37
chr10_-_77140757 0.37 ENST00000637862.2
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
chr7_+_66075876 0.37 ENST00000395332.8
ASL
argininosuccinate lyase
chr10_+_97572771 0.37 ENST00000370655.6
ENST00000455090.1
ANKRD2
ankyrin repeat domain 2
chr17_-_7179544 0.35 ENST00000619926.4
ASGR1
asialoglycoprotein receptor 1
chrX_-_30309387 0.35 ENST00000378970.5
NR0B1
nuclear receptor subfamily 0 group B member 1
chr14_-_58427134 0.35 ENST00000555930.6
TIMM9
translocase of inner mitochondrial membrane 9
chr18_-_63158208 0.35 ENST00000678301.1
BCL2
BCL2 apoptosis regulator
chr11_+_122838492 0.35 ENST00000227348.9
CRTAM
cytotoxic and regulatory T cell molecule
chr14_-_80211472 0.35 ENST00000557125.1
ENST00000438257.9
ENST00000422005.7
DIO2
iodothyronine deiodinase 2
chr2_+_172821575 0.35 ENST00000397087.7
RAPGEF4
Rap guanine nucleotide exchange factor 4
chr19_-_2783241 0.35 ENST00000676943.1
ENST00000589251.5
ENST00000221566.7
ENST00000676984.1
SGTA
small glutamine rich tetratricopeptide repeat containing alpha
chr2_-_69643152 0.34 ENST00000606389.7
AAK1
AP2 associated kinase 1
chr6_+_54111437 0.34 ENST00000502396.6
MLIP
muscular LMNA interacting protein
chr17_-_29761390 0.34 ENST00000324677.12
SSH2
slingshot protein phosphatase 2
chr12_+_48482492 0.34 ENST00000548364.7
C12orf54
chromosome 12 open reading frame 54
chr19_-_2783308 0.33 ENST00000677562.1
ENST00000677754.1
SGTA
small glutamine rich tetratricopeptide repeat containing alpha
chr11_+_57542641 0.33 ENST00000527972.5
ENST00000399154.3
SMTNL1
smoothelin like 1
chr10_+_97572493 0.33 ENST00000307518.9
ENST00000298808.9
ANKRD2
ankyrin repeat domain 2
chr1_-_155910881 0.33 ENST00000609492.1
ENST00000368322.7
RIT1
Ras like without CAAX 1
chr2_-_164842140 0.33 ENST00000496396.1
ENST00000629362.2
ENST00000445474.2
ENST00000483743.6
COBLL1
cordon-bleu WH2 repeat protein like 1
chr6_+_20401864 0.33 ENST00000346618.8
ENST00000613242.4
E2F3
E2F transcription factor 3
chr20_+_1894145 0.33 ENST00000400068.7
SIRPA
signal regulatory protein alpha
chr3_-_190449782 0.33 ENST00000354905.3
TMEM207
transmembrane protein 207
chr17_+_6996042 0.33 ENST00000251535.11
ALOX12
arachidonate 12-lipoxygenase, 12S type
chr8_-_130016395 0.32 ENST00000523509.5
CYRIB
CYFIP related Rac1 interactor B
chr14_-_58427158 0.32 ENST00000555097.1
ENST00000556367.6
ENST00000555404.5
TIMM9
translocase of inner mitochondrial membrane 9
chr3_+_141386393 0.32 ENST00000503809.5
ZBTB38
zinc finger and BTB domain containing 38
chr14_-_58427114 0.31 ENST00000556007.6
TIMM9
translocase of inner mitochondrial membrane 9
chr1_+_39081316 0.31 ENST00000484793.5
MACF1
microtubule actin crosslinking factor 1
chr11_+_55827219 0.31 ENST00000378397.1
OR5L2
olfactory receptor family 5 subfamily L member 2
chr17_-_29761415 0.31 ENST00000649863.1
SSH2
slingshot protein phosphatase 2
chr11_+_1838970 0.31 ENST00000381911.6
TNNI2
troponin I2, fast skeletal type
chr22_-_29388530 0.31 ENST00000357586.7
ENST00000432560.6
ENST00000405198.6
ENST00000317368.11
AP1B1
adaptor related protein complex 1 subunit beta 1
chr13_+_75549734 0.31 ENST00000563635.5
ENST00000377595.8
ENSG00000261553.5
UCHL3
novel transcript
ubiquitin C-terminal hydrolase L3
chr10_+_73998104 0.30 ENST00000372755.7
ENST00000211998.10
VCL
vinculin
chr3_-_196287649 0.30 ENST00000441879.5
ENST00000292823.6
ENST00000431016.6
ENST00000411591.5
PCYT1A
phosphate cytidylyltransferase 1, choline, alpha
chr19_+_39498938 0.30 ENST00000356433.10
ENST00000596614.5
ENST00000205143.4
DLL3
delta like canonical Notch ligand 3
chr6_-_88963409 0.30 ENST00000369475.7
ENST00000538899.2
RNGTT
RNA guanylyltransferase and 5'-phosphatase
chr5_+_40679907 0.30 ENST00000302472.4
PTGER4
prostaglandin E receptor 4
chr10_+_63133279 0.30 ENST00000277746.11
NRBF2
nuclear receptor binding factor 2
chr6_-_127519191 0.30 ENST00000525778.5
SOGA3
SOGA family member 3
chr10_+_63133247 0.29 ENST00000435510.6
NRBF2
nuclear receptor binding factor 2
chr8_+_27774530 0.29 ENST00000305188.13
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr2_+_55232672 0.29 ENST00000404735.1
ENST00000272317.11
RPS27A
ribosomal protein S27a
chr14_-_80211268 0.29 ENST00000556811.5
DIO2
iodothyronine deiodinase 2
chr20_-_13990609 0.29 ENST00000284951.10
ENST00000378072.5
SEL1L2
SEL1L2 adaptor subunit of ERAD E3 ligase
chr11_+_113908983 0.29 ENST00000537778.5
HTR3B
5-hydroxytryptamine receptor 3B
chr19_-_46471484 0.29 ENST00000313683.15
ENST00000602246.1
PNMA8A
PNMA family member 8A
chr6_-_88963573 0.28 ENST00000369485.9
RNGTT
RNA guanylyltransferase and 5'-phosphatase
chr2_+_196713117 0.28 ENST00000409270.5
CCDC150
coiled-coil domain containing 150
chr19_-_46471407 0.28 ENST00000438932.2
PNMA8A
PNMA family member 8A
chr7_+_102748972 0.28 ENST00000413034.3
ENST00000409231.7
ENST00000418198.5
FAM185A
family with sequence similarity 185 member A
chr8_-_130016622 0.28 ENST00000518283.5
ENST00000519110.5
CYRIB
CYFIP related Rac1 interactor B
chr1_+_184051865 0.28 ENST00000644815.1
TSEN15
tRNA splicing endonuclease subunit 15
chrX_+_71301742 0.28 ENST00000373829.8
ENST00000538820.1
ITGB1BP2
integrin subunit beta 1 binding protein 2
chr1_+_15684284 0.28 ENST00000375799.8
ENST00000375793.2
PLEKHM2
pleckstrin homology and RUN domain containing M2
chr9_-_120793377 0.28 ENST00000684001.1
ENST00000684405.1
ENST00000608872.6
FBXW2
F-box and WD repeat domain containing 2
chr5_-_163460048 0.27 ENST00000517501.1
NUDCD2
NudC domain containing 2
chr1_+_20070156 0.27 ENST00000375108.4
PLA2G5
phospholipase A2 group V
chr1_+_184051678 0.27 ENST00000643231.1
TSEN15
tRNA splicing endonuclease subunit 15
chr22_-_19178402 0.26 ENST00000451283.5
SLC25A1
solute carrier family 25 member 1
chr19_+_19528861 0.26 ENST00000436027.9
YJEFN3
YjeF N-terminal domain containing 3
chr9_+_128552558 0.26 ENST00000372731.8
ENST00000630804.2
ENST00000372739.7
ENST00000627441.2
ENST00000358161.9
ENST00000636257.1
SPTAN1
spectrin alpha, non-erythrocytic 1
chr19_+_589873 0.25 ENST00000251287.3
HCN2
hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2
chr15_-_79923647 0.25 ENST00000485386.1
ENST00000479961.1
ENST00000494999.1
ST20
ST20-MTHFS
suppressor of tumorigenicity 20
ST20-MTHFS readthrough
chr3_-_194486945 0.25 ENST00000645538.1
ENST00000645319.2
ATP13A3
ATPase 13A3
chr16_+_85908988 0.25 ENST00000566369.1
IRF8
interferon regulatory factor 8
chr19_+_19528901 0.25 ENST00000514277.6
YJEFN3
YjeF N-terminal domain containing 3
chr13_-_33185994 0.24 ENST00000255486.8
STARD13
StAR related lipid transfer domain containing 13
chr17_-_41065879 0.24 ENST00000394015.3
KRTAP2-4
keratin associated protein 2-4
chr8_+_144095054 0.24 ENST00000318911.5
CYC1
cytochrome c1
chr11_-_35360050 0.24 ENST00000644868.1
ENST00000643454.1
ENST00000646080.1
SLC1A2
solute carrier family 1 member 2
chr1_-_29181809 0.24 ENST00000466448.4
ENST00000373795.7
SRSF4
serine and arginine rich splicing factor 4
chr9_-_120793343 0.24 ENST00000684047.1
FBXW2
F-box and WD repeat domain containing 2
chr19_-_48673017 0.24 ENST00000270235.11
ENST00000596844.5
NTN5
netrin 5
chr7_+_45574358 0.23 ENST00000297323.12
ADCY1
adenylate cyclase 1
chr2_-_229921903 0.23 ENST00000389045.7
ENST00000409677.5
TRIP12
thyroid hormone receptor interactor 12
chr2_+_74530018 0.23 ENST00000437202.1
HTRA2
HtrA serine peptidase 2
chr16_-_68015911 0.23 ENST00000574912.1
DPEP2NB
DPEP2 neighbor
chr1_+_28438104 0.22 ENST00000633167.1
ENST00000373836.4
PHACTR4
phosphatase and actin regulator 4
chrX_+_68693629 0.22 ENST00000374597.3
STARD8
StAR related lipid transfer domain containing 8

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.2 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.9 3.4 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.9 6.0 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.7 2.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.4 1.2 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.4 1.6 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.3 1.3 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.3 1.0 GO:1903028 positive regulation of opsonization(GO:1903028)
0.3 2.0 GO:0060631 regulation of meiosis I(GO:0060631)
0.3 0.9 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.3 0.3 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.3 1.1 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.3 1.1 GO:1900535 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.2 1.1 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.2 2.3 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 0.6 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.2 0.6 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.2 0.8 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.2 1.6 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 0.7 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.2 0.8 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.4 GO:0030221 basophil differentiation(GO:0030221)
0.1 1.5 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.4 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.1 1.0 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.1 2.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 1.4 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.1 1.3 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 1.0 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.3 GO:2001301 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.1 0.3 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.1 0.4 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.1 0.5 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 2.4 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 2.0 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.5 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.4 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.1 0.7 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.4 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.3 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.1 0.4 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.1 1.1 GO:0007144 female meiosis I(GO:0007144)
0.1 2.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.2 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.3 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.5 GO:0006203 dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061)
0.1 1.0 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 1.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.2 GO:0090133 corticotropin hormone secreting cell differentiation(GO:0060128) mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.1 0.2 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.1 0.2 GO:0001828 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.1 1.5 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.1 0.2 GO:0098976 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 0.3 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 0.5 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.1 0.2 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.2 GO:0014016 proximal/distal axis specification(GO:0009946) neuroblast differentiation(GO:0014016)
0.1 0.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.3 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.2 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.2 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.4 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.1 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.6 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.8 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 1.1 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.3 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.7 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.7 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.4 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.5 GO:0019532 oxalate transport(GO:0019532)
0.0 0.8 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.6 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.2 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.5 GO:0034214 protein hexamerization(GO:0034214)
0.0 2.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.6 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.2 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.2 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.1 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.0 0.3 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.3 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.4 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.8 GO:0034063 stress granule assembly(GO:0034063)
0.0 1.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.3 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.6 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.1 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.2 GO:0031427 response to methotrexate(GO:0031427)
0.0 1.5 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.0 0.4 GO:0030238 male sex determination(GO:0030238) Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0019474 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 1.7 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.3 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 3.4 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.2 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.0 0.1 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.0 0.4 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.2 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.4 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.2 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.6 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 1.2 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 0.1 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 1.0 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.3 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.2 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.5 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 1.0 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.3 GO:0045907 positive regulation of vasoconstriction(GO:0045907)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0036117 hyaluranon cable(GO:0036117)
0.1 1.0 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.4 GO:0071752 dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752)
0.1 0.7 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.6 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 1.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.4 GO:0045160 myosin I complex(GO:0045160)
0.1 0.3 GO:0098855 HCN channel complex(GO:0098855)
0.1 2.2 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.6 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 3.4 GO:0001533 cornified envelope(GO:0001533)
0.1 2.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.2 GO:0060203 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.8 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 1.0 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 1.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.5 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.2 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.6 GO:0032426 stereocilium tip(GO:0032426)
0.0 2.0 GO:0000795 synaptonemal complex(GO:0000795)
0.0 1.7 GO:0002102 podosome(GO:0002102)
0.0 6.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.2 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.3 GO:0042587 glycogen granule(GO:0042587)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.8 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.0 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.4 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.7 GO:0000791 euchromatin(GO:0000791)
0.0 2.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.7 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 2.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.9 GO:0042641 actomyosin(GO:0042641)
0.0 2.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.3 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0032432 actin filament bundle(GO:0032432)
0.0 1.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.4 GO:0046930 pore complex(GO:0046930)
0.0 0.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.6 6.2 GO:0050692 DBD domain binding(GO:0050692)
0.4 6.0 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.4 1.9 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.3 1.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.2 1.5 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.2 0.7 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 2.3 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 1.6 GO:0019237 centromeric DNA binding(GO:0019237)
0.2 0.6 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.2 0.5 GO:0044714 GTP diphosphatase activity(GO:0036219) 2-hydroxy-adenosine triphosphate pyrophosphatase activity(GO:0044713) 2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity(GO:0044714) ATP diphosphatase activity(GO:0047693)
0.2 0.5 GO:0052857 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.2 0.6 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 0.5 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.4 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.1 1.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.4 GO:0004056 argininosuccinate lyase activity(GO:0004056)
0.1 0.3 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165) hepoxilin-epoxide hydrolase activity(GO:0047977)
0.1 0.9 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.3 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.1 0.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.7 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.6 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.8 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 0.3 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.1 0.7 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.6 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 0.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 2.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.2 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.1 1.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.5 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 0.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 1.0 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.3 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 2.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.3 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.3 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.8 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.4 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.4 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 1.0 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.4 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.5 GO:0015368 calcium:cation antiporter activity(GO:0015368)
0.0 0.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 1.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.4 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.7 GO:0005549 odorant binding(GO:0005549)
0.0 0.6 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0031014 troponin T binding(GO:0031014)
0.0 1.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.6 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 1.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0051538 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 1.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 4.4 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.6 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.4 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 1.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.2 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 3.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.8 GO:0002020 protease binding(GO:0002020)
0.0 0.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 3.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 2.5 PID ATM PATHWAY ATM pathway
0.0 1.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 2.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.5 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 1.3 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 5.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.0 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.2 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.9 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 1.8 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 1.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 2.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.0 REACTOME KINESINS Genes involved in Kinesins
0.1 1.6 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.0 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 5.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 6.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.0 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 1.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.8 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 1.1 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.4 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 1.9 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.6 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.6 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport