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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for TP63

Z-value: 1.06

Motif logo

Transcription factors associated with TP63

Gene Symbol Gene ID Gene Info
ENSG00000073282.14 TP63

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TP63hg38_v1_chr3_+_189789643_1897896700.792.5e-07Click!

Activity profile of TP63 motif

Sorted Z-values of TP63 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TP63

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_-_51001138 10.56 ENST00000593490.1
kallikrein related peptidase 8
chr12_-_57237090 4.58 ENST00000556732.1
NDUFA4 mitochondrial complex associated like 2
chr19_-_18940289 3.85 ENST00000542541.6
ENST00000433218.6
homer scaffold protein 3
chr20_-_44651683 3.65 ENST00000537820.1
ENST00000372874.9
adenosine deaminase
chr3_-_50303565 3.27 ENST00000266031.8
ENST00000395143.6
ENST00000457214.6
ENST00000447605.2
ENST00000395144.7
ENST00000418723.1
hyaluronidase 1
chr12_-_52452139 3.27 ENST00000252252.4
keratin 6B
chr12_+_119178920 3.25 ENST00000281938.7
heat shock protein family B (small) member 8
chr12_+_119178953 3.21 ENST00000674542.1
heat shock protein family B (small) member 8
chr3_-_111595339 3.18 ENST00000317012.5
zinc finger BED-type containing 2
chr4_-_10021490 3.14 ENST00000264784.8
solute carrier family 2 member 9
chr1_+_17249088 3.03 ENST00000375460.3
peptidyl arginine deiminase 3
chrX_-_154374623 2.85 ENST00000369850.10
filamin A
chr10_+_100347225 2.85 ENST00000370355.3
stearoyl-CoA desaturase
chr4_-_174522315 2.69 ENST00000514584.5
15-hydroxyprostaglandin dehydrogenase
chr18_+_36544544 2.61 ENST00000591635.5
formin homology 2 domain containing 3
chr2_-_31138429 2.55 ENST00000349752.10
polypeptide N-acetylgalactosaminyltransferase 14
chr2_+_233059838 2.53 ENST00000359570.9
inositol polyphosphate-5-phosphatase D
chr1_+_86424154 2.37 ENST00000370565.5
chloride channel accessory 2
chr19_+_41219177 2.35 ENST00000301178.9
AXL receptor tyrosine kinase
chr20_-_6123019 2.33 ENST00000217289.9
ENST00000536936.1
fermitin family member 1
chr19_+_18386150 2.29 ENST00000252809.3
growth differentiation factor 15
chr6_+_36676489 2.09 ENST00000448526.6
cyclin dependent kinase inhibitor 1A
chr7_+_80638510 2.06 ENST00000433696.6
ENST00000538969.5
ENST00000544133.5
CD36 molecule
chr6_+_36676455 2.04 ENST00000615513.4
cyclin dependent kinase inhibitor 1A
chr7_+_80638662 2.03 ENST00000394788.7
CD36 molecule
chr1_+_37692506 2.02 ENST00000373055.6
cell division cycle associated 8
chr12_-_124863783 1.92 ENST00000546215.5
ENST00000415380.6
ENST00000545493.1
ENST00000261693.11
ENST00000680596.1
scavenger receptor class B member 1
chr1_+_37692463 1.91 ENST00000327331.2
cell division cycle associated 8
chr6_+_121435595 1.83 ENST00000649003.1
ENST00000282561.4
gap junction protein alpha 1
chr20_-_54173976 1.82 ENST00000216862.8
cytochrome P450 family 24 subfamily A member 1
chr1_-_47190013 1.79 ENST00000294338.7
PDZK1 interacting protein 1
chr17_-_41620801 1.75 ENST00000648859.1
keratin 17
chr6_+_106098933 1.64 ENST00000369089.3
PR/SET domain 1
chr12_+_119667859 1.63 ENST00000541640.5
protein kinase AMP-activated non-catalytic subunit beta 1
chr17_+_28335571 1.63 ENST00000544907.6
TNF alpha induced protein 1
chr12_-_124863902 1.61 ENST00000339570.9
ENST00000680556.1
scavenger receptor class B member 1
chr17_+_28335718 1.60 ENST00000226225.7
TNF alpha induced protein 1
chr12_+_119668109 1.59 ENST00000229328.10
ENST00000630317.1
protein kinase AMP-activated non-catalytic subunit beta 1
chr8_-_23164020 1.59 ENST00000312584.4
TNF receptor superfamily member 10d
chr8_+_23102913 1.59 ENST00000356864.4
TNF receptor superfamily member 10c
chr9_+_35906179 1.52 ENST00000354323.3
histidine rich carboxyl terminus 1
chrX_+_150980504 1.49 ENST00000419110.5
high mobility group box 3
chr7_+_80638633 1.44 ENST00000447544.7
ENST00000482059.6
CD36 molecule
chr8_-_23225061 1.42 ENST00000613472.1
ENST00000221132.8
TNF receptor superfamily member 10a
chr18_+_63476927 1.42 ENST00000489441.5
ENST00000382771.9
ENST00000424602.1
serpin family B member 5
chr14_+_51489112 1.40 ENST00000356218.8
FERM domain containing 6
chr1_+_24319342 1.38 ENST00000361548.9
grainyhead like transcription factor 3
chr1_+_24319511 1.37 ENST00000356046.6
grainyhead like transcription factor 3
chrX_+_9912434 1.32 ENST00000418909.6
shroom family member 2
chrX_+_152917830 1.30 ENST00000318529.12
zinc finger protein 185 with LIM domain
chr8_-_23069012 1.26 ENST00000347739.3
ENST00000276431.9
TNF receptor superfamily member 10b
chr10_-_103452356 1.25 ENST00000260743.10
calcium homeostasis modulator family member 2
chr2_-_164842011 1.25 ENST00000409184.8
ENST00000456693.5
cordon-bleu WH2 repeat protein like 1
chr2_+_233691607 1.19 ENST00000373424.5
ENST00000441351.1
UDP glucuronosyltransferase family 1 member A6
chr19_+_48321454 1.18 ENST00000599704.5
epithelial membrane protein 3
chr12_-_52191981 1.17 ENST00000313234.9
keratin 80
chr11_+_78188871 1.16 ENST00000528910.5
ENST00000529308.6
ubiquitin specific peptidase 35
chr1_-_92961440 1.15 ENST00000370310.5
ENST00000615519.4
ENST00000613902.4
ENST00000616709.4
divergent protein kinase domain 1A
chr17_+_77453993 1.15 ENST00000592951.5
septin 9
chr10_-_103452384 1.14 ENST00000369788.7
calcium homeostasis modulator family member 2
chr2_-_201642653 1.13 ENST00000621467.4
transmembrane protein 237
chr12_-_52192007 1.13 ENST00000394815.3
keratin 80
chr1_-_153615858 1.12 ENST00000476873.5
S100 calcium binding protein A14
chr8_-_48921419 1.12 ENST00000020945.4
snail family transcriptional repressor 2
chr14_-_91244669 1.08 ENST00000650645.1
G protein-coupled receptor 68
chr15_-_88913362 1.07 ENST00000558029.5
ENST00000268150.13
ENST00000542878.5
ENST00000268151.11
ENST00000566497.5
milk fat globule EGF and factor V/VIII domain containing
chrX_+_2752024 1.06 ENST00000644266.2
ENST00000419513.7
ENST00000509484.3
ENST00000381174.10
Xg glycoprotein (Xg blood group)
chr8_+_81280527 1.03 ENST00000297258.11
fatty acid binding protein 5
chr12_-_52493250 1.01 ENST00000330722.7
keratin 6A
chr19_+_43533384 1.00 ENST00000601282.1
zinc finger protein 575
chr5_+_154190749 0.98 ENST00000377661.2
polypeptide N-acetylgalactosaminyltransferase 10
chr9_+_113536497 0.98 ENST00000462143.5
regulator of G protein signaling 3
chr1_+_113905156 0.97 ENST00000650596.1
DNA cross-link repair 1B
chr19_+_7049321 0.97 ENST00000381393.3
methyl-CpG binding domain protein 3 like 2
chr10_+_97584347 0.96 ENST00000370649.3
ENST00000370646.9
novel protein
4-hydroxy-2-oxoglutarate aldolase 1
chr1_-_209651291 0.96 ENST00000391911.5
ENST00000415782.1
laminin subunit beta 3
chr11_+_706595 0.95 ENST00000531348.5
ENST00000530636.5
EPS8 like 2
chrX_-_132218124 0.93 ENST00000342983.6
RAP2C, member of RAS oncogene family
chr1_-_93847150 0.93 ENST00000370244.5
BCAR3 adaptor protein, NSP family member
chr1_-_17011891 0.93 ENST00000341676.9
ENST00000326735.13
ENST00000452699.5
ATPase cation transporting 13A2
chr3_+_111911604 0.91 ENST00000495180.1
pleckstrin homology like domain family B member 2
chr3_-_44976117 0.90 ENST00000342790.8
ENST00000424952.7
ENST00000339420.7
ENST00000296127.7
ENST00000455235.5
zinc finger DHHC-type palmitoyltransferase 3
chr6_+_54846735 0.89 ENST00000306858.8
family with sequence similarity 83 member B
chr3_+_136957948 0.89 ENST00000329582.9
interleukin 20 receptor subunit beta
chr5_+_175478551 0.88 ENST00000321442.10
ENST00000502393.5
ENST00000506963.1
sideroflexin 1
chr1_-_152580511 0.86 ENST00000368787.4
late cornified envelope 3D
chr11_-_8168987 0.86 ENST00000425599.6
ENST00000531450.1
ENST00000309737.11
ENST00000419822.2
ENST00000335425.7
ENST00000343202.8
RIC3 acetylcholine receptor chaperone
chr19_+_35371290 0.84 ENST00000597214.1
G protein-coupled receptor 42
chr5_+_154190725 0.83 ENST00000425427.6
ENST00000297107.11
polypeptide N-acetylgalactosaminyltransferase 10
chr19_+_535824 0.82 ENST00000606065.3
cell division cycle 34, ubiqiutin conjugating enzyme
chr1_+_154327737 0.82 ENST00000672630.1
ATPase phospholipid transporting 8B2
chr10_-_68471882 0.81 ENST00000551118.6
DNA replication helicase/nuclease 2
chr8_+_22995831 0.80 ENST00000522948.5
Rho related BTB domain containing 2
chr2_-_164842140 0.80 ENST00000496396.1
ENST00000629362.2
ENST00000445474.2
ENST00000483743.6
cordon-bleu WH2 repeat protein like 1
chr19_+_35370929 0.80 ENST00000454971.2
G protein-coupled receptor 42
chr11_+_18412292 0.79 ENST00000541669.6
ENST00000280704.8
lactate dehydrogenase C
chr3_-_57079287 0.75 ENST00000338458.8
ENST00000468727.5
Rho guanine nucleotide exchange factor 3
chr11_+_76782250 0.75 ENST00000533752.1
ENST00000612930.1
tsukushi, small leucine rich proteoglycan
chr3_-_33659097 0.75 ENST00000461133.8
ENST00000496954.2
cytoplasmic linker associated protein 2
chr12_-_95790755 0.72 ENST00000343702.9
ENST00000344911.8
netrin 4
chr11_+_18266254 0.71 ENST00000532858.5
ENST00000649195.1
ENST00000356524.9
ENST00000405158.2
serum amyloid A1
chr12_+_6494087 0.70 ENST00000382457.8
ENST00000315579.10
non-SMC condensin I complex subunit D2
chr16_+_23641452 0.69 ENST00000300087.7
ENST00000563998.5
dynactin subunit 5
chr6_-_100881281 0.67 ENST00000369143.2
ENST00000369162.7
ENST00000324723.10
ENST00000522650.5
activating signal cointegrator 1 complex subunit 3
chr11_+_62123991 0.66 ENST00000533896.5
ENST00000278849.4
ENST00000394818.8
inner centromere protein
chr15_+_32615501 0.66 ENST00000361627.8
ENST00000567348.5
ENST00000563864.5
ENST00000543522.5
Rho GTPase activating protein 11A
chr10_-_68471911 0.65 ENST00000358410.8
ENST00000399180.3
DNA replication helicase/nuclease 2
chr1_-_120054225 0.64 ENST00000602566.6
notch receptor 2
chr21_+_42893265 0.63 ENST00000340344.4
NADH:ubiquinone oxidoreductase subunit V3
chr15_+_68277724 0.63 ENST00000306917.5
fem-1 homolog B
chr12_+_68809002 0.63 ENST00000539479.6
ENST00000393415.7
ENST00000523991.5
ENST00000543323.5
ENST00000393416.7
MDM2 proto-oncogene
chr11_-_111911759 0.62 ENST00000650687.2
crystallin alpha B
chr1_-_12618198 0.60 ENST00000616661.5
dehydrogenase/reductase 3
chr10_+_88990736 0.60 ENST00000357339.6
ENST00000652046.1
ENST00000355279.2
Fas cell surface death receptor
chr16_+_56336727 0.59 ENST00000568375.2
G protein subunit alpha o1
chr19_+_35358821 0.58 ENST00000594310.1
free fatty acid receptor 3
chr14_-_37172553 0.58 ENST00000331299.6
solute carrier family 25 member 21
chr2_-_46941710 0.57 ENST00000409207.5
multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
chr19_+_35358460 0.56 ENST00000327809.5
free fatty acid receptor 3
chr21_+_42893280 0.56 ENST00000354250.7
NADH:ubiquinone oxidoreductase subunit V3
chr3_+_184362599 0.56 ENST00000455712.5
RNA polymerase II, I and III subunit H
chr10_+_73772270 0.55 ENST00000372841.8
ENST00000394790.2
fucosyltransferase 11
chr16_+_29995661 0.55 ENST00000304516.11
INO80 complex subunit E
chr7_-_75073844 0.54 ENST00000614461.4
ENST00000618035.4
RCC1 like
chr8_-_116766255 0.54 ENST00000276682.8
eukaryotic translation initiation factor 3 subunit H
chr2_-_130509287 0.53 ENST00000615053.3
ENST00000631234.1
ENST00000451531.7
POTE ankyrin domain family member I
chr21_-_26090035 0.53 ENST00000448850.5
amyloid beta precursor protein
chr4_+_2793077 0.52 ENST00000503393.8
SH3 domain binding protein 2
chr16_+_57976435 0.51 ENST00000290871.10
ENST00000441824.4
testis, prostate and placenta expressed
chr3_+_44799187 0.51 ENST00000425755.5
kinesin family member 15
chr3_-_112133218 0.50 ENST00000488580.5
ENST00000308910.9
ENST00000460387.6
ENST00000484193.5
ENST00000487901.1
germinal center associated signaling and motility
chr4_-_10116779 0.50 ENST00000499869.7
WD repeat domain 1
chr17_+_51153628 0.50 ENST00000555572.1
ENST00000013034.3
NME1-NME2 readthrough
NME/NM23 nucleoside diphosphate kinase 1
chr17_-_14236862 0.50 ENST00000420162.7
ENST00000431716.2
CMT1A duplicated region transcript 15
chr13_-_48413105 0.50 ENST00000620633.5
lysophosphatidic acid receptor 6
chr12_-_84911178 0.49 ENST00000681688.1
solute carrier family 6 member 15
chr5_+_171387757 0.49 ENST00000677297.1
ENST00000521672.6
ENST00000679190.1
ENST00000351986.10
ENST00000676589.1
ENST00000679233.1
ENST00000677357.1
ENST00000296930.10
ENST00000393820.2
ENST00000523622.1
nucleophosmin 1
chr16_+_29996201 0.48 ENST00000620599.4
ENST00000563197.6
ENST00000567254.5
ENST00000567705.5
INO80 complex subunit E
chr3_+_44976236 0.48 ENST00000265564.8
exosome component 7
chr15_+_51829644 0.48 ENST00000308580.12
tropomodulin 3
chr17_+_7650916 0.48 ENST00000250111.9
ATPase Na+/K+ transporting subunit beta 2
chr1_-_220089818 0.48 ENST00000498791.6
ENST00000480959.6
3'(2'), 5'-bisphosphate nucleotidase 1
chr20_+_36091409 0.48 ENST00000202028.9
erythrocyte membrane protein band 4.1 like 1
chr10_+_11017863 0.47 ENST00000633077.1
ENST00000542579.5
ENST00000632065.1
CUGBP Elav-like family member 2
chr2_+_130611440 0.47 ENST00000409602.2
POTE ankyrin domain family member J
chr19_-_45785659 0.47 ENST00000537879.1
ENST00000596586.5
ENST00000595946.1
DM1 locus, WD repeat containing
novel protein
chr5_-_179624578 0.47 ENST00000505811.5
ENST00000515714.5
ENST00000513225.5
ENST00000503664.1
ENST00000356731.9
ENST00000523137.5
heterogeneous nuclear ribonucleoprotein H1
chr17_-_44385332 0.47 ENST00000648408.1
integrin subunit alpha 2b
chr10_+_123154364 0.47 ENST00000368859.6
ENST00000368865.9
BUB3 mitotic checkpoint protein
chr22_+_39014249 0.46 ENST00000361441.5
apolipoprotein B mRNA editing enzyme catalytic subunit 3C
chr9_+_135714582 0.46 ENST00000630792.2
potassium sodium-activated channel subfamily T member 1
chr7_+_142939343 0.46 ENST00000458732.1
ENST00000409607.5
LLLL and CFNLAS motif containing 1
chr20_+_836052 0.45 ENST00000246100.3
family with sequence similarity 110 member A
chr1_-_32817311 0.45 ENST00000373477.9
ENST00000675785.1
tyrosyl-tRNA synthetase 1
chr13_+_51584435 0.45 ENST00000612477.1
ENST00000298125.7
WD repeat and FYVE domain containing 2
chrX_-_139642835 0.45 ENST00000536274.5
MCF.2 cell line derived transforming sequence
chr19_+_19668877 0.44 ENST00000415784.6
zinc finger protein 101
chr6_+_31723344 0.44 ENST00000480039.5
ENST00000375810.8
ENST00000375805.6
ENST00000375809.7
ENST00000649779.1
ENST00000375804.6
ENST00000375814.7
megakaryocyte and platelet inhibitory receptor G6b
chr4_-_143905529 0.44 ENST00000358615.9
ENST00000437468.2
glycophorin E (MNS blood group)
chr15_-_55408018 0.43 ENST00000569205.5
cell cycle progression 1
chr2_+_177392734 0.43 ENST00000680770.1
ENST00000637633.2
ENST00000679459.1
ENST00000409888.1
ENST00000264167.11
ENST00000642466.2
alkylglycerone phosphate synthase
chr17_+_51153551 0.43 ENST00000393196.8
ENST00000336097.7
ENST00000480143.5
ENST00000511355.5
ENST00000393193.6
ENST00000376392.10
NME/NM23 nucleoside diphosphate kinase 1
NME1-NME2 readthrough
chr10_-_86957582 0.42 ENST00000372027.10
multimerin 2
chr2_+_112721486 0.42 ENST00000327581.4
5'-nucleotidase domain containing 4
chrX_+_48476021 0.42 ENST00000396894.8
ENST00000019019.6
ENST00000348411.3
FtsJ RNA 2'-O-methyltransferase 1
chrX_-_154409246 0.42 ENST00000369807.6
deoxyribonuclease 1 like 1
chr1_+_11980181 0.41 ENST00000444836.5
ENST00000674817.1
ENST00000675053.1
ENST00000675817.1
ENST00000675298.1
ENST00000676369.1
ENST00000412236.2
ENST00000675530.1
ENST00000674548.1
ENST00000674658.1
ENST00000674910.1
ENST00000675231.1
mitofusin 2
chr19_+_41860236 0.41 ENST00000601492.5
ENST00000600467.6
ENST00000598742.6
ENST00000221975.6
ENST00000598261.2
ribosomal protein S19
chr19_-_15125095 0.40 ENST00000600984.5
ilvB acetolactate synthase like
chr20_+_36605734 0.40 ENST00000344795.8
ENST00000373852.9
RAB5 interacting factor
chr1_-_157552455 0.39 ENST00000368190.7
ENST00000368189.3
Fc receptor like 5
chr3_-_53130405 0.39 ENST00000467048.1
ENST00000296292.8
ENST00000394738.7
RFT1 homolog
chr11_-_18012883 0.39 ENST00000530613.5
ENST00000532389.5
ENST00000529728.5
ENST00000532265.5
secretion regulating guanine nucleotide exchange factor
chr22_+_37805218 0.38 ENST00000340857.4
H1.0 linker histone
chr22_-_38181772 0.38 ENST00000430886.5
ENST00000667521.1
ENST00000663895.1
ENST00000402064.5
ENST00000332509.8
ENST00000664587.1
phospholipase A2 group VI
chr17_-_4187106 0.38 ENST00000574736.1
ankyrin repeat and FYVE domain containing 1
chrX_+_154379203 0.38 ENST00000369835.3
ENST00000369842.9
emerin
chr19_-_8698789 0.38 ENST00000324436.5
actin like 9
chr20_+_36605820 0.37 ENST00000342422.3
RAB5 interacting factor
chr6_-_13328332 0.37 ENST00000606530.1
ENST00000607658.5
ENST00000356436.8
ENST00000450347.5
ENST00000452989.5
ENST00000422136.5
ENST00000446018.5
ENST00000379291.5
ENST00000379300.8
ENST00000606370.5
ENST00000343141.8
ENST00000379307.6
ENST00000607230.1
TBC1 domain family member 7
chr4_-_105708639 0.36 ENST00000416543.5
ENST00000515819.1
ENST00000420368.6
ENST00000503746.5
ENST00000433009.1
ENST00000340139.10
integrator complex subunit 12
chrX_-_139642889 0.36 ENST00000370576.9
MCF.2 cell line derived transforming sequence
chr1_-_31644866 0.36 ENST00000373703.5
penta-EF-hand domain containing 1
chr16_+_51553436 0.36 ENST00000565308.2
heterogeneous nuclear ribonucleoprotein A1 pseudogene 48
chr1_+_113905290 0.36 ENST00000650450.2
DNA cross-link repair 1B
chr5_-_157059109 0.36 ENST00000523175.6
ENST00000522693.5
hepatitis A virus cellular receptor 1
chr4_+_15374541 0.36 ENST00000382383.7
ENST00000429690.5
C1q and TNF related 7
chr14_+_39233884 0.36 ENST00000553728.1
MIA SH3 domain ER export factor 2
chr16_-_47459130 0.35 ENST00000565940.6
integrin alpha FG-GAP repeat containing 1
chr1_+_22001654 0.34 ENST00000290122.8
chymotrypsin like elastase 3A
chr3_-_14178569 0.34 ENST00000285021.12
XPC complex subunit, DNA damage recognition and repair factor
chr1_-_113905020 0.34 ENST00000432415.5
ENST00000369571.2
ENST00000256658.8
ENST00000369564.5
adaptor related protein complex 4 subunit beta 1
chr3_-_8963434 0.33 ENST00000418463.5
ENST00000421052.5
ENST00000264926.7
RAD18 E3 ubiquitin protein ligase
chr19_-_10309783 0.33 ENST00000403352.1
ENST00000403903.7
zinc finger GATA like protein 1
chr7_+_73328152 0.33 ENST00000252037.5
ENST00000431982.6
FKBP prolyl isomerase family member 6 (inactive)
chr19_-_12723925 0.33 ENST00000425528.6
ENST00000589337.5
ENST00000588216.5
transportin 2
chr5_-_142644201 0.33 ENST00000394496.2
ENST00000610990.4
fibroblast growth factor 1
chr19_-_46413548 0.33 ENST00000307522.5
coiled-coil domain containing 8
chr5_-_140557414 0.33 ENST00000336283.9
steroid receptor RNA activator 1
chr19_-_4518465 0.33 ENST00000633942.1
perilipin 4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0070256 germinal center B cell differentiation(GO:0002314) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) xanthine metabolic process(GO:0046110) negative regulation of mucus secretion(GO:0070256)
1.2 3.5 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.9 2.8 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.8 2.3 GO:0048817 negative regulation of hair follicle maturation(GO:0048817)
0.8 3.0 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.7 10.6 GO:0031642 negative regulation of myelination(GO:0031642)
0.6 2.5 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.6 5.5 GO:2000332 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.5 1.6 GO:1990654 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.5 3.3 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.5 4.1 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.5 1.8 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.5 1.8 GO:0042369 vitamin D catabolic process(GO:0042369)
0.4 2.7 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.4 1.1 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.3 0.9 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.3 1.5 GO:1902990 DNA replication, removal of RNA primer(GO:0043137) mitochondrial DNA repair(GO:0043504) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.3 1.1 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.3 1.0 GO:0001897 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
0.2 1.4 GO:0003383 apical constriction(GO:0003383)
0.2 2.9 GO:2001300 lipoxin metabolic process(GO:2001300)
0.2 1.3 GO:0031627 telomeric loop formation(GO:0031627)
0.2 3.2 GO:0035878 nail development(GO:0035878)
0.2 0.8 GO:0019249 lactate biosynthetic process(GO:0019249)
0.2 3.1 GO:0046415 urate metabolic process(GO:0046415)
0.2 0.8 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.2 4.7 GO:0051639 actin filament network formation(GO:0051639)
0.2 5.5 GO:0007398 ectoderm development(GO:0007398)
0.2 0.5 GO:1903259 exon-exon junction complex disassembly(GO:1903259)
0.2 0.5 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.2 1.4 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.2 0.6 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.2 0.6 GO:0072717 transcription factor catabolic process(GO:0036369) cellular response to actinomycin D(GO:0072717)
0.2 0.9 GO:0018197 peptidyl-aspartic acid modification(GO:0018197)
0.1 0.1 GO:0045799 positive regulation of chromatin assembly or disassembly(GO:0045799)
0.1 3.9 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 0.4 GO:0060264 respiratory burst involved in inflammatory response(GO:0002536) regulation of respiratory burst involved in inflammatory response(GO:0060264) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 1.7 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.5 GO:0016333 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.1 0.5 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.1 0.5 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.1 1.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.7 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 1.8 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.1 0.7 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.6 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.1 0.5 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1 0.6 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.1 0.5 GO:0048669 collateral sprouting in absence of injury(GO:0048669)
0.1 1.9 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.1 0.3 GO:0070512 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.1 1.2 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 1.3 GO:0045176 apical protein localization(GO:0045176)
0.1 0.4 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 2.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.5 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.1 0.8 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.2 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.1 0.1 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.1 3.2 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 0.9 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.2 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.1 0.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 3.8 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 0.1 GO:0060435 bronchiole development(GO:0060435)
0.1 0.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.6 GO:0001866 NK T cell proliferation(GO:0001866)
0.1 4.4 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.5 GO:0060699 regulation of endoribonuclease activity(GO:0060699)
0.1 0.2 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.1 0.2 GO:1902905 positive regulation of fibril organization(GO:1902905)
0.1 0.4 GO:0044375 peroxisome membrane biogenesis(GO:0016557) regulation of peroxisome size(GO:0044375)
0.1 0.5 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.9 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 7.2 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 1.1 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.8 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.4 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.2 GO:0032439 endosome localization(GO:0032439)
0.0 0.9 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.2 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 2.8 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0 1.2 GO:0032060 bleb assembly(GO:0032060)
0.0 0.5 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 1.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.4 GO:0046836 glycolipid transport(GO:0046836)
0.0 0.3 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.0 4.6 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.4 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.4 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.4 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 1.0 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.6 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.4 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 0.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.2 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.0 0.9 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.4 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.0 1.2 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.0 0.1 GO:0033058 directional locomotion(GO:0033058)
0.0 0.2 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.6 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 3.6 GO:0070268 cornification(GO:0070268)
0.0 0.6 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.1 GO:0051594 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.2 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.3 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.9 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094)
0.0 0.8 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 1.0 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0034414 tRNA 3'-trailer cleavage, endonucleolytic(GO:0034414) tRNA 3'-trailer cleavage(GO:0042779) mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 0.7 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.0 0.9 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.9 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.1 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 1.0 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.4 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 1.0 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.2 GO:0006203 dGTP catabolic process(GO:0006203)
0.0 0.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.5 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.8 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.4 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.3 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.9 GO:0006826 iron ion transport(GO:0006826)
0.0 0.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.3 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.0 2.3 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 2.5 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.3 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.1 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.6 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.2 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.4 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.5 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.8 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.1 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.7 GO:0035904 aorta development(GO:0035904)
0.0 0.2 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0036117 hyaluranon cable(GO:0036117)
0.8 4.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.6 2.8 GO:0031523 Myb complex(GO:0031523)
0.5 1.5 GO:0005760 gamma DNA polymerase complex(GO:0005760)
0.4 3.9 GO:0032133 chromosome passenger complex(GO:0032133)
0.3 0.9 GO:1905103 integral component of lysosomal membrane(GO:1905103)
0.3 0.9 GO:1990298 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.3 4.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 0.7 GO:0000799 nuclear condensin complex(GO:0000799)
0.1 6.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 3.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 1.0 GO:0005610 laminin-5 complex(GO:0005610)
0.1 2.3 GO:0033643 host cell part(GO:0033643)
0.1 0.1 GO:0044753 amphisome(GO:0044753)
0.1 3.5 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.5 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 0.5 GO:0042643 actomyosin, actin portion(GO:0042643)
0.1 0.7 GO:0000801 central element(GO:0000801)
0.1 1.7 GO:0045180 basal cortex(GO:0045180)
0.1 1.8 GO:0005916 fascia adherens(GO:0005916)
0.1 3.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 6.7 GO:0045095 keratin filament(GO:0045095)
0.1 6.2 GO:0045178 basal part of cell(GO:0045178)
0.1 0.5 GO:1990812 growth cone filopodium(GO:1990812)
0.1 1.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.3 GO:0071942 XPC complex(GO:0071942)
0.1 3.1 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.3 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.1 0.6 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.3 GO:1990393 3M complex(GO:1990393)
0.0 2.3 GO:0031941 filamentous actin(GO:0031941)
0.0 0.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 3.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.6 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.7 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 1.1 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 1.1 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 2.0 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 3.6 GO:0043296 apical junction complex(GO:0043296)
0.0 0.7 GO:0000795 synaptonemal complex(GO:0000795)
0.0 1.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0097413 Lewy body(GO:0097413)
0.0 0.4 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.5 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 0.1 GO:0097179 protease inhibitor complex(GO:0097179)
0.0 0.8 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.7 GO:0016235 aggresome(GO:0016235)
0.0 0.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 5.9 GO:0045569 TRAIL binding(GO:0045569)
1.2 3.5 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.8 4.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.8 3.0 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.7 2.8 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.7 5.5 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.7 3.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.6 2.8 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.5 2.7 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.4 2.5 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.4 1.8 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.3 0.9 GO:1903135 cupric ion binding(GO:1903135)
0.3 1.5 GO:0016890 site-specific endodeoxyribonuclease activity, specific for altered base(GO:0016890)
0.3 3.1 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.3 0.8 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.2 1.8 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.2 1.6 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 3.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.2 4.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2 3.8 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.2 0.9 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 3.7 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 4.6 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 3.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.6 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.8 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 2.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.3 GO:0000403 Y-form DNA binding(GO:0000403)
0.1 0.8 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.1 0.6 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 1.0 GO:0004630 phospholipase D activity(GO:0004630)
0.1 0.4 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.1 1.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.2 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 0.5 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 2.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.7 GO:0043237 laminin-1 binding(GO:0043237)
0.1 1.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.2 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.2 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
0.1 0.5 GO:0045159 myosin II binding(GO:0045159)
0.1 0.6 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.1 0.2 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165) hepoxilin-epoxide hydrolase activity(GO:0047977)
0.1 0.5 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.6 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 1.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.5 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.6 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 1.5 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 0.4 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 0.3 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.1 0.5 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 1.0 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 2.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0004583 alpha-1,3-mannosyltransferase activity(GO:0000033) dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.5 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.2 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.2 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 1.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.4 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 2.3 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.9 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.9 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.7 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 5.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.0 0.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.6 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.7 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.4 GO:0008252 nucleotidase activity(GO:0008252) 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 1.1 GO:0042379 chemokine receptor binding(GO:0042379)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 2.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 5.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.0 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.6 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.4 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.4 GO:0071949 FAD binding(GO:0071949)
0.0 0.5 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.7 GO:0005310 dicarboxylic acid transmembrane transporter activity(GO:0005310)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 1.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 1.0 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 1.2 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.0 GO:0004743 pyruvate kinase activity(GO:0004743)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 12.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 5.4 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 5.8 PID AURORA B PATHWAY Aurora B signaling
0.1 0.8 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 1.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.6 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 2.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.9 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 2.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 2.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 3.2 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.4 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.7 PID P73PATHWAY p73 transcription factor network
0.0 0.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.5 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.8 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.2 3.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 3.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 3.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 3.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 3.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 4.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 1.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.9 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 2.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.8 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 5.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 6.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.0 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.6 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.8 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.9 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.4 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.9 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 1.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.1 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation