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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for TP73

Z-value: 0.39

Motif logo

Transcription factors associated with TP73

Gene Symbol Gene ID Gene Info
ENSG00000078900.15 TP73

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TP73hg38_v1_chr1_+_3652508_36525300.096.2e-01Click!

Activity profile of TP73 motif

Sorted Z-values of TP73 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TP73

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_+_41114430 1.12 ENST00000331105.7
cytochrome P450 family 2 subfamily F member 1
chr9_-_135499846 0.72 ENST00000429260.7
chromosome 9 open reading frame 116
chr8_+_119873710 0.66 ENST00000523492.5
ENST00000286234.6
DEP domain containing MTOR interacting protein
chr16_+_84145256 0.57 ENST00000378553.10
dynein axonemal assembly factor 1
chr3_+_50205254 0.47 ENST00000614032.5
ENST00000445096.5
solute carrier family 38 member 3
chr14_-_25049889 0.42 ENST00000419632.6
ENST00000396700.5
syntaxin binding protein 6
chr14_-_25050111 0.41 ENST00000323944.9
syntaxin binding protein 6
chrX_+_131058340 0.41 ENST00000276211.10
ENST00000370922.5
Rho GTPase activating protein 36
chr16_+_4958289 0.40 ENST00000251170.12
SEC14 like lipid binding 5
chr19_-_35490456 0.34 ENST00000338897.4
ENST00000484218.6
keratinocyte differentiation associated protein
chrX_+_73447042 0.33 ENST00000373514.3
caudal type homeobox 4
chr11_+_77589911 0.31 ENST00000313578.4
aquaporin 11
chr11_+_46277648 0.29 ENST00000621158.5
cAMP responsive element binding protein 3 like 1
chr5_+_38258551 0.28 ENST00000322350.10
EGF like, fibronectin type III and laminin G domains
chr5_+_38258373 0.27 ENST00000354891.7
EGF like, fibronectin type III and laminin G domains
chr14_+_52314280 0.26 ENST00000557436.1
ENST00000245457.6
prostaglandin E receptor 2
chr19_+_12995554 0.24 ENST00000397661.6
nuclear factor I X
chr11_+_60429567 0.24 ENST00000300190.7
membrane spanning 4-domains A5
chr10_-_60141004 0.24 ENST00000355288.6
ankyrin 3
chrX_-_38327496 0.23 ENST00000642395.2
ENST00000645032.1
ENST00000644238.1
ENST00000642558.1
ENST00000339363.7
ENST00000644337.1
ENST00000647261.1
retinitis pigmentosa GTPase regulator
chr1_+_109539865 0.23 ENST00000618721.4
ENST00000527748.5
ENST00000616874.1
G protein-coupled receptor 61
chr19_+_43716095 0.23 ENST00000596627.1
immunity related GTPase cinema
chr15_+_74174403 0.23 ENST00000560862.1
ENST00000395118.1
immunoglobulin superfamily containing leucine rich repeat
chr1_+_46671821 0.20 ENST00000334122.5
ENST00000415500.1
testis expressed 38
chr19_-_13937991 0.20 ENST00000254320.7
ENST00000586075.1
podocan like 1
chr14_+_103100144 0.19 ENST00000380069.7
exocyst complex component 3 like 4
chr18_+_13277351 0.19 ENST00000679091.1
low density lipoprotein receptor class A domain containing 4
chr1_-_160862880 0.19 ENST00000368034.9
CD244 molecule
chr2_-_26641363 0.18 ENST00000288861.5
calcium and integrin binding family member 4
chr3_-_66038537 0.18 ENST00000483466.5
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr10_-_97426044 0.18 ENST00000536831.5
ENST00000622320.4
ENST00000439965.6
ribosomal RNA processing 12 homolog
chr17_+_74431338 0.16 ENST00000342648.9
ENST00000652232.1
ENST00000481232.2
G protein-coupled receptor class C group 5 member C
chr17_-_44123628 0.16 ENST00000587135.1
ENST00000225983.10
ENST00000682912.1
ENST00000588703.5
histone deacetylase 5
chr14_-_100569780 0.15 ENST00000355173.7
brain enriched guanylate kinase associated
chr1_+_46671871 0.15 ENST00000564373.1
testis expressed 38
chr18_-_55585773 0.14 ENST00000563824.5
ENST00000626425.2
ENST00000566514.5
ENST00000568673.5
ENST00000562847.5
ENST00000568147.5
transcription factor 4
chr12_+_113057687 0.14 ENST00000257600.3
deltex E3 ubiquitin ligase 1
chr2_+_158968608 0.14 ENST00000263635.8
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr19_+_3721719 0.13 ENST00000589378.5
tight junction protein 3
chr17_+_20009320 0.13 ENST00000679049.1
ENST00000472876.5
ENST00000583528.6
ENST00000680019.1
ENST00000681593.1
ENST00000395527.8
ENST00000583482.7
ENST00000679255.1
ENST00000681202.1
ENST00000677914.1
sperm antigen with calponin homology and coiled-coil domains 1
chr2_-_229271221 0.13 ENST00000392054.7
ENST00000409462.1
ENST00000392055.8
phosphotyrosine interaction domain containing 1
chr22_+_35383106 0.13 ENST00000678411.1
heme oxygenase 1
chr1_+_162497805 0.13 ENST00000538489.5
ENST00000489294.2
U2AF homology motif kinase 1
chr6_-_33289189 0.13 ENST00000374617.9
WD repeat domain 46
chr15_+_40844018 0.13 ENST00000344051.8
ENST00000562057.6
serine peptidase inhibitor, Kunitz type 1
chr1_-_236065079 0.12 ENST00000264187.7
ENST00000366595.7
nidogen 1
chr22_-_37580075 0.12 ENST00000215886.6
galectin 2
chr19_+_35351552 0.12 ENST00000246553.3
free fatty acid receptor 1
chr18_-_55586092 0.12 ENST00000563888.6
ENST00000540999.5
ENST00000627685.2
transcription factor 4
chr11_+_63681573 0.12 ENST00000354497.4
reticulon 3
chrX_-_132094263 0.12 ENST00000370879.5
FERM domain containing 7
chr1_+_26159071 0.12 ENST00000374268.5
family with sequence similarity 110 member D
chr11_+_63681483 0.12 ENST00000339997.8
ENST00000540798.5
ENST00000545432.5
ENST00000543552.5
ENST00000377819.10
ENST00000537981.5
reticulon 3
chr12_+_49295138 0.12 ENST00000257860.9
peripherin
chr11_+_63681444 0.12 ENST00000341307.6
ENST00000356000.7
ENST00000542238.5
reticulon 3
chr16_-_8797624 0.11 ENST00000333050.7
transmembrane protein 186
chr5_+_126423363 0.11 ENST00000285689.8
GRAM domain containing 2B
chr1_+_16043736 0.11 ENST00000619181.4
chloride voltage-gated channel Kb
chr17_+_7888783 0.11 ENST00000330494.12
ENST00000358181.8
chromodomain helicase DNA binding protein 3
chr10_-_103479240 0.11 ENST00000369783.4
calcium homeostasis modulator 3
chr1_+_239386942 0.11 ENST00000675184.1
cholinergic receptor muscarinic 3
chr8_+_62248591 0.10 ENST00000519049.6
sodium/potassium transporting ATPase interacting 3
chr5_+_126423122 0.10 ENST00000515200.5
GRAM domain containing 2B
chr16_+_8797813 0.10 ENST00000268261.9
ENST00000569958.5
phosphomannomutase 2
chrX_-_139642518 0.10 ENST00000370573.8
ENST00000338585.6
MCF.2 cell line derived transforming sequence
chr17_-_76027212 0.10 ENST00000586740.1
envoplakin
chr12_-_91179472 0.10 ENST00000550099.5
ENST00000546391.5
decorin
chr14_+_103100328 0.10 ENST00000559116.1
exocyst complex component 3 like 4
chr17_+_67825664 0.10 ENST00000321892.8
bromodomain PHD finger transcription factor
chr2_+_219418369 0.09 ENST00000373960.4
desmin
chr9_+_6757940 0.09 ENST00000381309.8
lysine demethylase 4C
chr12_-_31729010 0.09 ENST00000537562.5
ENST00000537960.5
ENST00000281471.11
ENST00000536761.5
ENST00000542781.5
ENST00000457428.6
antagonist of mitotic exit network 1 homolog
chr19_-_291132 0.09 ENST00000327790.7
phospholipid phosphatase 2
chr11_-_236821 0.09 ENST00000529382.5
ENST00000528469.1
sirtuin 3
chr4_+_6269869 0.09 ENST00000506362.2
wolframin ER transmembrane glycoprotein
chr16_+_12901757 0.09 ENST00000423335.2
shisa family member 9
chr5_+_126423176 0.09 ENST00000542322.5
ENST00000544396.5
GRAM domain containing 2B
chr19_+_17215716 0.08 ENST00000593597.1
unconventional SNARE in the ER 1
chr3_+_42160160 0.08 ENST00000341421.7
ENST00000396175.5
trafficking kinesin protein 1
chr17_-_82101850 0.08 ENST00000583053.1
coiled-coil domain containing 57
chr11_+_111977300 0.08 ENST00000615255.1
DIX domain containing 1
chr10_+_62374361 0.08 ENST00000395254.8
zinc finger protein 365
chr10_-_31928864 0.08 ENST00000375245.8
ENST00000396144.8
Rho GTPase activating protein 12
chr9_-_20382461 0.08 ENST00000380321.5
ENST00000629733.3
MLLT3 super elongation complex subunit
chr10_-_95441015 0.08 ENST00000371241.5
ENST00000354106.7
ENST00000371239.5
ENST00000361941.7
ENST00000277982.9
ENST00000371245.7
sorbin and SH3 domain containing 1
chr1_+_100352925 0.07 ENST00000644813.1
cell division cycle 14A
chr20_-_63572455 0.07 ENST00000467148.1
helicase with zinc finger 2
chr17_+_32928126 0.07 ENST00000579849.6
ENST00000578289.5
ENST00000439138.5
transmembrane protein 98
chr17_-_49414871 0.07 ENST00000504124.6
ENST00000300408.8
ENST00000614445.5
prohibitin
chr17_+_67825494 0.07 ENST00000306378.11
ENST00000544778.6
bromodomain PHD finger transcription factor
chr12_-_6635938 0.07 ENST00000329858.9
lysophosphatidic acid receptor 5
chr9_-_114505437 0.07 ENST00000374057.3
ENST00000362057.4
ENST00000673697.1
whirlin
chr2_+_127535746 0.07 ENST00000428314.5
ENST00000409816.7
myosin VIIB
chr9_-_129620743 0.07 ENST00000619117.1
ENST00000372478.4
chromosome 9 open reading frame 50
chr10_-_31928790 0.07 ENST00000375250.9
ENST00000344936.7
Rho GTPase activating protein 12
chr17_-_49414802 0.06 ENST00000511832.6
ENST00000419140.7
ENST00000617874.5
prohibitin
chr19_+_19516216 0.06 ENST00000507754.9
ENST00000503283.5
ENST00000428459.6
ENST00000555938.1
NADH:ubiquinone oxidoreductase subunit A13
novel protein
chr17_-_76027296 0.06 ENST00000301607.8
envoplakin
chr9_+_36169382 0.06 ENST00000335119.4
calicin
chr1_+_16043776 0.06 ENST00000375679.9
chloride voltage-gated channel Kb
chr1_-_182672882 0.06 ENST00000367557.8
ENST00000258302.8
regulator of G protein signaling 8
chr8_+_37796850 0.06 ENST00000412232.3
adhesion G protein-coupled receptor A2
chr17_-_81514629 0.06 ENST00000681052.1
ENST00000575659.6
actin gamma 1
chr14_+_104699368 0.06 ENST00000675207.1
inverted formin 2
chr10_+_68901258 0.06 ENST00000373585.8
DExD-box helicase 50
chr16_+_12901591 0.06 ENST00000558583.3
shisa family member 9
chr16_+_56191476 0.06 ENST00000262493.12
G protein subunit alpha o1
chr15_+_75206398 0.06 ENST00000565074.1
chromosome 15 open reading frame 39
chr8_+_37796906 0.06 ENST00000315215.11
adhesion G protein-coupled receptor A2
chr6_+_31547560 0.05 ENST00000376148.9
ENST00000376145.8
NFKB inhibitor like 1
chr22_+_39570753 0.05 ENST00000407673.5
ENST00000401624.5
ENST00000404898.5
ENST00000402142.4
calcium voltage-gated channel subunit alpha1 I
chr11_+_31812307 0.05 ENST00000643436.1
ENST00000646959.1
ENST00000645942.1
ENST00000530348.5
PAX6 upstream antisense RNA
novel protein
chr11_+_119149029 0.05 ENST00000619701.5
ATP binding cassette subfamily G member 4
chr8_+_144504131 0.05 ENST00000394955.3
glutamic--pyruvic transaminase
chr1_-_203086001 0.05 ENST00000241651.5
myogenin
chr5_-_11904417 0.05 ENST00000304623.13
catenin delta 2
chr2_+_95274439 0.04 ENST00000317620.14
ENST00000403131.6
ENST00000317668.8
prominin 2
chr11_+_71527267 0.04 ENST00000398536.6
keratin associated protein 5-7
chr19_+_43716070 0.04 ENST00000244314.6
immunity related GTPase cinema
chr20_-_54173976 0.04 ENST00000216862.8
cytochrome P450 family 24 subfamily A member 1
chr11_+_66466745 0.04 ENST00000349459.10
ENST00000320740.12
ENST00000524466.5
ENST00000526296.5
pellino E3 ubiquitin protein ligase family member 3
chr1_-_34859717 0.04 ENST00000423898.1
ENST00000521580.3
ENST00000456842.1
small integral membrane protein 12
chr18_-_4455257 0.04 ENST00000581527.5
DLG associated protein 1
chr2_+_219572304 0.04 ENST00000243786.3
inhibin subunit alpha
chr6_-_122471774 0.04 ENST00000339697.5
serine incorporator 1
chr1_-_182672232 0.04 ENST00000508450.5
regulator of G protein signaling 8
chr17_+_45241067 0.04 ENST00000587489.5
formin like 1
chr16_-_2531408 0.04 ENST00000567119.1
ENST00000565480.1
cementum protein 1
chrX_-_139642889 0.04 ENST00000370576.9
MCF.2 cell line derived transforming sequence
chr17_+_56153458 0.04 ENST00000318698.6
ENST00000682825.1
ENST00000566473.6
ankyrin repeat and fibronectin type III domain containing 1
chr14_+_21749163 0.04 ENST00000390427.3
T cell receptor alpha variable 5
chr20_+_36876119 0.04 ENST00000602922.5
ENST00000217320.8
TBC/LysM-associated domain containing 2
chr4_+_6716131 0.03 ENST00000320776.5
biogenesis of lysosomal organelles complex 1 subunit 4
chr1_+_239386556 0.03 ENST00000676153.1
cholinergic receptor muscarinic 3
chr3_-_48898813 0.03 ENST00000319017.5
ENST00000430379.5
solute carrier family 25 member 20
chr1_-_51878799 0.03 ENST00000354831.11
ENST00000544028.5
nardilysin convertase
chrX_+_68499021 0.03 ENST00000462683.6
Yip1 domain family member 6
chr10_-_89535575 0.03 ENST00000371790.5
solute carrier family 16 member 12
chr2_+_69741974 0.03 ENST00000409920.5
annexin A4
chr1_-_235161215 0.02 ENST00000447801.5
ENST00000408888.8
ENST00000429912.1
RNA binding motif protein 34
chr9_+_84669760 0.02 ENST00000304053.10
neurotrophic receptor tyrosine kinase 2
chr15_+_75206014 0.02 ENST00000567617.1
chromosome 15 open reading frame 39
chr1_-_51878711 0.02 ENST00000352171.12
nardilysin convertase
chr17_-_42683057 0.02 ENST00000591765.1
C-C motif chemokine receptor 10
chr1_-_220046432 0.02 ENST00000609181.5
ENST00000366923.8
glutamyl-prolyl-tRNA synthetase 1
chr17_+_21288029 0.02 ENST00000526076.6
ENST00000361818.9
ENST00000316920.10
mitogen-activated protein kinase kinase 3
chr17_+_39200275 0.02 ENST00000225430.9
ribosomal protein L19
chr16_+_74999003 0.01 ENST00000335325.9
ENST00000320619.10
zinc and ring finger 1
chr3_+_48440246 0.01 ENST00000438607.2
translation machinery associated 7 homolog
chr12_+_82358496 0.01 ENST00000248306.8
ENST00000548200.5
methyltransferase like 25
chr8_+_62248933 0.01 ENST00000523211.5
ENST00000524201.1
sodium/potassium transporting ATPase interacting 3
chr3_+_20040437 0.01 ENST00000263754.5
lysine acetyltransferase 2B
chr17_-_40867200 0.01 ENST00000647902.1
ENST00000251643.5
keratin 12
chr17_+_39200334 0.01 ENST00000579260.5
ENST00000582193.5
ribosomal protein L19
chr6_+_155216637 0.01 ENST00000275246.11
TIAM Rac1 associated GEF 2
chr1_+_27959943 0.01 ENST00000675575.1
ENST00000373884.6
XK related 8
chr17_+_39200302 0.01 ENST00000579374.5
ribosomal protein L19
chr19_-_1863497 0.01 ENST00000617223.1
ENST00000250916.6
Kruppel like factor 16
chr14_-_89954659 0.01 ENST00000555070.1
ENST00000316738.12
ENST00000538485.6
ENST00000556609.5
novel transcript
EF-hand calcium binding domain 11
chr19_+_41860236 0.01 ENST00000601492.5
ENST00000600467.6
ENST00000598742.6
ENST00000221975.6
ENST00000598261.2
ribosomal protein S19
chr11_+_58579052 0.00 ENST00000316059.7
ZFP91 zinc finger protein, atypical E3 ubiquitin ligase
chr6_-_46735351 0.00 ENST00000274793.12
phospholipase A2 group VII
chr10_+_62804710 0.00 ENST00000373783.3
2-aminoethanethiol dioxygenase

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0015817 histidine transport(GO:0015817) cellular response to potassium ion starvation(GO:0051365) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1 0.6 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 1.1 GO:0051601 exocyst localization(GO:0051601)
0.1 0.2 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.1 0.3 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.2 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.0 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0 1.1 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.1 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0 0.3 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.0 0.1 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.1 GO:2001170 negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859) negative regulation of ATP biosynthetic process(GO:2001170)
0.0 0.7 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.4 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:1903892 negative regulation of ATF6-mediated unfolded protein response(GO:1903892)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210)
0.0 0.0 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.2 GO:0010991 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.0 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.3 GO:0042599 lamellar body(GO:0042599)
0.0 0.0 GO:0044393 microspike(GO:0044393)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858) azole transmembrane transporter activity(GO:1901474)
0.1 1.1 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.0 GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.6 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.0 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.3 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors