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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for VDR

Z-value: 0.83

Motif logo

Transcription factors associated with VDR

Gene Symbol Gene ID Gene Info
ENSG00000111424.12 VDR

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
VDRhg38_v1_chr12_-_47905003_479050430.355.6e-02Click!

Activity profile of VDR motif

Sorted Z-values of VDR motif

Network of associatons between targets according to the STRING database.

First level regulatory network of VDR

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_+_85449584 2.95 ENST00000369651.7
5'-nucleotidase ecto
chr10_-_5499544 2.47 ENST00000380332.5
calmodulin like 5
chr5_-_39270623 2.12 ENST00000512138.1
ENST00000646045.2
FYN binding protein 1
chr16_-_2720217 1.78 ENST00000302641.8
serine protease 27
chr17_-_38068634 1.75 ENST00000622206.2
TBC1 domain family member 3C
chr17_+_2796404 1.73 ENST00000366401.8
ENST00000254695.13
ENST00000542807.1
RAP1 GTPase activating protein 2
chr17_-_37989048 1.61 ENST00000617678.2
ENST00000612727.5
TBC1 domain family member 3L
chr17_+_37924415 1.61 ENST00000620247.1
TBC1 domain family member 3K
chr17_-_38192555 1.60 ENST00000620215.3
TBC1 domain family member 3
chr17_+_38003976 1.59 ENST00000616101.4
TBC1 domain family member 3D
chr17_+_36323884 1.58 ENST00000569055.2
TBC1 domain family member 3G
chr17_-_36439566 1.55 ENST00000620210.1
TBC1 domain family member 3F
chr7_+_144003929 1.43 ENST00000408922.3
olfactory receptor family 6 subfamily B member 1
chr20_-_54173976 1.41 ENST00000216862.8
cytochrome P450 family 24 subfamily A member 1
chr17_-_36264514 1.41 ENST00000618620.4
ENST00000621034.1
TBC1 domain family member 3I
chr11_-_28108109 1.39 ENST00000263181.7
kinesin family member 18A
chr14_+_94174284 1.38 ENST00000304338.8
protein phosphatase 4 regulatory subunit 4
chr7_+_155298561 1.38 ENST00000476756.1
insulin induced gene 1
chr11_-_65900375 1.36 ENST00000312562.7
FOS like 1, AP-1 transcription factor subunit
chr11_-_61815106 1.34 ENST00000539419.5
ENST00000545245.5
ENST00000545405.5
ENST00000542506.5
fatty acid desaturase 1
chr1_-_74733253 1.33 ENST00000417775.5
crystallin zeta
chr17_-_36388423 1.32 ENST00000610350.3
TBC1 domain family member 3H
chr2_+_209653171 1.30 ENST00000447185.5
microtubule associated protein 2
chr11_-_65900413 1.20 ENST00000448083.6
ENST00000531493.5
ENST00000532401.1
FOS like 1, AP-1 transcription factor subunit
chr4_+_141636611 1.17 ENST00000514653.5
interleukin 15
chr20_+_64063481 1.14 ENST00000415602.5
transcription elongation factor A2
chr9_+_136945234 1.06 ENST00000371634.7
complement C8 gamma chain
chr3_-_59049947 1.05 ENST00000491845.5
ENST00000472469.5
ENST00000482387.6
ENST00000295966.11
CFAP20 domain containing
chr1_-_221742074 0.97 ENST00000366899.4
dual specificity phosphatase 10
chr16_+_590200 0.92 ENST00000563109.1
RAB40C, member RAS oncogene family
chr1_-_204190324 0.90 ENST00000638118.1
renin
chr8_+_94641199 0.89 ENST00000646773.1
ENST00000454170.7
epithelial splicing regulatory protein 1
chr9_+_128882502 0.89 ENST00000259324.5
leucine rich repeat containing 8 VRAC subunit A
chr17_-_36176636 0.89 ENST00000611257.5
ENST00000616006.1
TBC1 domain family member 3B
chr17_+_38127951 0.87 ENST00000621587.2
TBC1 domain family member 3E
chr1_-_6490564 0.84 ENST00000377725.5
ENST00000340850.10
pleckstrin homology and RhoGEF domain containing G5
chr4_+_141636923 0.82 ENST00000529613.5
interleukin 15
chr18_+_44697118 0.81 ENST00000677077.1
SET binding protein 1
chr2_-_85398734 0.81 ENST00000453973.5
capping actin protein, gelsolin like
chr5_-_141673160 0.81 ENST00000513878.5
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chrX_-_153674325 0.81 ENST00000370142.5
ENST00000447676.6
pregnancy up-regulated nonubiquitous CaM kinase
chr16_+_2429427 0.80 ENST00000397066.9
cyclin F
chr1_+_153259684 0.79 ENST00000368742.4
loricrin cornified envelope precursor protein
chr8_+_94641074 0.78 ENST00000423620.6
epithelial splicing regulatory protein 1
chr13_+_113667213 0.78 ENST00000335678.7
G protein-coupled receptor kinase 1
chr8_+_94641145 0.78 ENST00000433389.8
ENST00000358397.9
epithelial splicing regulatory protein 1
chr11_+_6603708 0.77 ENST00000532063.5
integrin linked kinase
chr11_+_6603740 0.77 ENST00000537806.5
ENST00000420936.6
ENST00000299421.9
ENST00000528995.5
ENST00000396751.6
integrin linked kinase
chr4_-_102345469 0.73 ENST00000356736.5
ENST00000682932.1
solute carrier family 39 member 8
chr19_-_35501878 0.71 ENST00000593342.5
ENST00000601650.1
ENST00000408915.6
dermokine
chr5_-_147831627 0.71 ENST00000510027.2
serine peptidase inhibitor Kazal type 1
chr8_-_143953845 0.70 ENST00000354958.6
plectin
chr3_+_156674579 0.70 ENST00000295924.12
TCDD inducible poly(ADP-ribose) polymerase
chr5_-_147831663 0.69 ENST00000296695.10
serine peptidase inhibitor Kazal type 1
chr8_-_141000937 0.68 ENST00000520892.5
protein tyrosine kinase 2
chr3_+_50155024 0.66 ENST00000414301.5
ENST00000450338.5
ENST00000413852.5
semaphorin 3F
chr3_+_50155305 0.66 ENST00000002829.8
ENST00000426511.5
semaphorin 3F
chr10_-_75235917 0.64 ENST00000469299.1
ENST00000372538.8
catechol-O-methyltransferase domain containing 1
chr8_+_10525529 0.64 ENST00000328655.8
ENST00000522210.1
serine protease 55
chr8_-_23069012 0.64 ENST00000347739.3
ENST00000276431.9
TNF receptor superfamily member 10b
chr17_-_66229380 0.63 ENST00000205948.11
apolipoprotein H
chr16_+_31108294 0.63 ENST00000287507.7
ENST00000394950.7
ENST00000219794.11
ENST00000561755.1
branched chain keto acid dehydrogenase kinase
chr6_+_31158518 0.61 ENST00000376255.4
ENST00000376257.8
transcription factor 19
chr9_-_91423819 0.61 ENST00000297689.4
nuclear factor, interleukin 3 regulated
chr6_+_38715288 0.61 ENST00000327475.11
dynein axonemal heavy chain 8
chr11_-_60952559 0.59 ENST00000538739.2
solute carrier family 15 member 3
chr3_+_101849505 0.59 ENST00000326151.9
ENST00000326172.9
NFKB inhibitor zeta
chr4_-_163613505 0.58 ENST00000339875.9
membrane associated ring-CH-type finger 1
chr12_+_56128217 0.58 ENST00000267113.4
ENST00000394048.10
extended synaptotagmin 1
chr7_-_36724457 0.58 ENST00000617537.5
ENST00000435386.1
acyloxyacyl hydrolase
chr14_+_104745960 0.58 ENST00000556623.1
ENST00000555674.1
adenylosuccinate synthase 1
chr7_+_66087761 0.57 ENST00000450043.2
novel protein
chr11_-_60952067 0.57 ENST00000681275.1
solute carrier family 15 member 3
chr1_+_156082563 0.56 ENST00000368301.6
lamin A/C
chr11_+_57597563 0.56 ENST00000619430.2
ENST00000457869.1
ENST00000340687.10
ENST00000278407.9
ENST00000378323.8
ENST00000378324.6
ENST00000403558.1
serpin family G member 1
chr7_-_36724543 0.55 ENST00000612871.4
acyloxyacyl hydrolase
chr10_-_33335074 0.55 ENST00000432372.6
neuropilin 1
chr3_-_197183806 0.53 ENST00000671246.1
ENST00000660553.1
discs large MAGUK scaffold protein 1
chr17_+_80415159 0.52 ENST00000520367.5
ENST00000518137.6
ENST00000523999.5
ENST00000323854.9
ENST00000522751.5
endonuclease V
chr6_+_33620329 0.51 ENST00000374316.9
inositol 1,4,5-trisphosphate receptor type 3
chr17_-_45410414 0.51 ENST00000532038.5
ENST00000528677.1
Rho GTPase activating protein 27
chr11_+_28108248 0.50 ENST00000406787.7
ENST00000403099.5
ENST00000407364.8
methyltransferase like 15
chr16_-_67183948 0.50 ENST00000561621.5
ENST00000563902.2
ENST00000290881.11
KIAA0895 like
chr7_+_155297776 0.49 ENST00000344756.8
ENST00000425172.1
ENST00000340368.9
ENST00000342407.5
insulin induced gene 1
chr2_+_9475049 0.49 ENST00000495797.1
isoamyl acetate hydrolyzing esterase 1 (putative)
chr19_+_38335775 0.49 ENST00000410018.5
ENST00000409235.8
ENST00000409410.6
cation channel sperm associated auxiliary subunit gamma
chr20_+_44401397 0.48 ENST00000682427.1
ENST00000681977.1
ENST00000684136.1
ENST00000684046.1
ENST00000684476.1
ENST00000619550.5
ENST00000682169.1
hepatocyte nuclear factor 4 alpha
chr10_-_33334625 0.48 ENST00000374875.5
ENST00000374822.8
ENST00000374867.7
neuropilin 1
chr11_+_74171266 0.46 ENST00000328257.13
ENST00000398427.6
protein phosphatase methylesterase 1
chr6_+_29111560 0.46 ENST00000377169.2
olfactory receptor family 2 subfamily J member 3
chr12_+_10505890 0.45 ENST00000538173.1
eukaryotic translation initiation factor 2 subunit gamma B
chr9_+_128276222 0.45 ENST00000608796.6
ENST00000419867.7
ENST00000418976.2
SWI5 homologous recombination repair protein
chr14_-_20333268 0.44 ENST00000358932.9
ENST00000557665.5
cyclin B1 interacting protein 1
chr12_+_48482492 0.44 ENST00000548364.7
chromosome 12 open reading frame 54
chr7_-_36724380 0.44 ENST00000617267.4
acyloxyacyl hydrolase
chr22_+_50185894 0.43 ENST00000380909.9
ENST00000303434.8
TraB domain containing
chr6_+_24774925 0.43 ENST00000356509.7
ENST00000230056.8
geminin DNA replication inhibitor
chr11_-_790062 0.42 ENST00000330106.5
cell cycle exit and neuronal differentiation 1
chr14_-_20333306 0.42 ENST00000353689.8
ENST00000437553.6
cyclin B1 interacting protein 1
chr19_+_589873 0.42 ENST00000251287.3
hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2
chr12_+_79045625 0.42 ENST00000552744.5
synaptotagmin 1
chr19_+_40191410 0.42 ENST00000253055.8
mitogen-activated protein kinase kinase kinase 10
chr12_+_57583101 0.41 ENST00000674858.1
ENST00000675433.1
ENST00000674980.1
kinesin family member 5A
chr20_+_31440626 0.41 ENST00000376309.4
defensin beta 123
chr21_-_46155567 0.41 ENST00000291670.9
ENST00000397748.5
ENST00000397743.1
ENST00000397746.8
formimidoyltransferase cyclodeaminase
chr10_-_33334898 0.40 ENST00000395995.5
neuropilin 1
chr2_+_219498857 0.40 ENST00000684669.1
ENST00000373917.7
ENST00000435316.6
ENST00000313597.10
ENST00000358215.8
ENST00000373908.5
ENST00000622191.2
ENST00000683752.1
ENST00000341142.8
GDP-mannose pyrophosphorylase A
chr3_+_180912444 0.39 ENST00000305586.11
FMR1 autosomal homolog 1
chr4_+_78057570 0.39 ENST00000502446.6
ENST00000325942.11
Fraser extracellular matrix complex subunit 1
chr16_+_67173935 0.39 ENST00000566871.5
nucleolar protein 3
chr10_+_132537778 0.37 ENST00000368594.8
inositol polyphosphate-5-phosphatase A
chr19_+_1407517 0.36 ENST00000336761.10
ENST00000233078.9
ENST00000592522.5
DAZ associated protein 1
chr14_+_22515623 0.35 ENST00000390509.1
T cell receptor alpha joining 28
chr16_+_31033781 0.35 ENST00000613541.1
syntaxin 4
chr11_-_111923722 0.35 ENST00000527950.5
crystallin alpha B
chr7_-_22500152 0.34 ENST00000406890.6
ENST00000678116.1
ENST00000424363.5
STEAP family member 1B
chr10_+_30434176 0.34 ENST00000263056.6
ENST00000375322.2
mitogen-activated protein kinase kinase kinase 8
chr6_+_30557287 0.33 ENST00000376560.8
proline rich 3
chr13_-_37598750 0.32 ENST00000379743.8
ENST00000379742.4
ENST00000379749.8
ENST00000379747.9
ENST00000541179.5
ENST00000541481.5
periostin
chr19_+_54966343 0.32 ENST00000537859.5
ENST00000585500.5
ENST00000427260.6
ENST00000448584.7
ENST00000263437.10
NLR family pyrin domain containing 2
chr11_-_3057386 0.32 ENST00000529772.5
ENST00000278224.13
ENST00000380525.9
cysteinyl-tRNA synthetase 1
chr16_+_1078781 0.32 ENST00000293897.5
somatostatin receptor 5
chr12_-_113966306 0.32 ENST00000545145.6
ENST00000392561.7
ENST00000261741.10
RNA binding motif protein 19
chr1_+_26021768 0.31 ENST00000374280.4
exostosin like glycosyltransferase 1
chr11_+_124739927 0.31 ENST00000284292.11
ENST00000412681.2
neurogranin
chr15_+_75647877 0.31 ENST00000308527.6
sorting nexin 33
chr2_+_108288639 0.31 ENST00000326853.9
sulfotransferase family 1C member 2
chr17_-_7261092 0.30 ENST00000574070.5
claudin 7
chr6_+_30557274 0.30 ENST00000376557.3
proline rich 3
chr7_-_151736304 0.29 ENST00000492843.6
protein kinase AMP-activated non-catalytic subunit gamma 2
chr19_-_15934853 0.29 ENST00000620614.4
ENST00000248041.12
cytochrome P450 family 4 subfamily F member 11
chr6_-_30556477 0.29 ENST00000376621.8
G protein nucleolar 1 (putative)
chr12_-_108827384 0.29 ENST00000326470.9
slingshot protein phosphatase 1
chr16_+_67173971 0.29 ENST00000563258.1
ENST00000568146.1
nucleolar protein 3
chr12_+_26938454 0.28 ENST00000229395.8
ENST00000544111.5
ENST00000546072.5
ENST00000327214.5
FGFR1 oncogene partner 2
chr11_-_60952134 0.28 ENST00000679573.1
ENST00000681882.1
ENST00000681951.1
ENST00000227880.8
solute carrier family 15 member 3
chr13_-_33285682 0.27 ENST00000336934.10
StAR related lipid transfer domain containing 13
chr6_+_167291329 0.27 ENST00000366829.2
unc-93 homolog A
chr16_+_15949549 0.27 ENST00000399408.7
ENST00000572882.3
ENST00000677164.1
ATP binding cassette subfamily C member 1
chr14_+_94581407 0.27 ENST00000553511.1
ENST00000329597.12
ENST00000554633.5
ENST00000555681.1
ENST00000554276.1
serpin family A member 5
chr1_+_92168915 0.26 ENST00000637221.2
BTB domain containing 8
chr11_+_925840 0.26 ENST00000448903.7
ENST00000525796.5
ENST00000534328.5
adaptor related protein complex 2 subunit alpha 2
chr6_+_167291309 0.25 ENST00000230256.8
unc-93 homolog A
chr1_-_243843164 0.24 ENST00000491219.6
ENST00000680056.1
ENST00000492957.2
AKT serine/threonine kinase 3
chr12_+_52233235 0.24 ENST00000331817.6
keratin 7
chr10_+_102394488 0.24 ENST00000369966.8
nuclear factor kappa B subunit 2
chr5_+_134526176 0.24 ENST00000681820.1
ENST00000512386.6
ENST00000612830.2
jade family PHD finger 2
chr18_-_50825373 0.24 ENST00000588444.5
ENST00000256425.6
ENST00000428869.6
maestro
chr18_-_46964408 0.23 ENST00000676383.1
elongin A3 family member D
chr19_-_48619127 0.23 ENST00000550973.5
ENST00000550645.5
ENST00000549273.5
ENST00000549920.6
ENST00000552588.5
ribosomal protein L18
chr16_-_31094727 0.23 ENST00000300851.10
ENST00000394975.3
vitamin K epoxide reductase complex subunit 1
chr1_+_23743462 0.23 ENST00000609199.1
elongin A
chr19_-_39840671 0.23 ENST00000597224.5
fibrillarin
chr6_+_46693835 0.22 ENST00000450697.1
tudor domain containing 6
chr10_+_117542416 0.21 ENST00000442245.5
empty spiracles homeobox 2
chr20_-_23751256 0.21 ENST00000398402.1
cystatin SN
chr16_-_31094890 0.21 ENST00000532364.1
ENST00000529564.1
ENST00000319788.11
ENST00000354895.4
novel protein, VKORC1 and PRSS53 readthrough
vitamin K epoxide reductase complex subunit 1
chr22_+_19131271 0.21 ENST00000399635.4
testis specific serine kinase 2
chr5_+_127290785 0.21 ENST00000503335.7
multiple EGF like domains 10
chr18_+_14748151 0.20 ENST00000358984.9
ENST00000665241.1
ankyrin repeat domain 30B
chr18_-_66604076 0.20 ENST00000540086.5
ENST00000580157.2
ENST00000262150.7
cadherin 19
chr9_-_36400860 0.20 ENST00000377877.4
ENST00000357058.7
ENST00000350199.8
ring finger protein 38
chr7_+_100101657 0.20 ENST00000421755.5
adaptor related protein complex 4 subunit mu 1
chr1_-_115338231 0.20 ENST00000369512.3
ENST00000680116.1
ENST00000681124.1
ENST00000675637.2
ENST00000676038.2
nerve growth factor
chr1_+_175067831 0.19 ENST00000239462.9
tenascin N
chr2_-_201619144 0.19 ENST00000439802.5
ENST00000286195.7
ENST00000439140.6
ENST00000450242.1
C2 calcium dependent domain containing 6
chr2_+_11612253 0.19 ENST00000396123.2
growth regulating estrogen receptor binding 1
chr3_-_71064915 0.19 ENST00000614176.5
ENST00000485326.7
forkhead box P1
chr17_+_81239310 0.19 ENST00000431388.3
NADH:ubiquinone oxidoreductase complex assembly factor 8
chr12_+_54284258 0.19 ENST00000677666.1
heterogeneous nuclear ribonucleoprotein A1
chr16_-_31094549 0.19 ENST00000394971.7
vitamin K epoxide reductase complex subunit 1
chr1_-_39691393 0.19 ENST00000372844.8
hippocalcin like 4
chr1_+_91949343 0.18 ENST00000448194.6
ENST00000470955.6
ENST00000362005.7
ENST00000370389.6
ENST00000394530.7
ENST00000423434.5
ENST00000440509.5
ENST00000426141.6
bromodomain testis associated
chr19_-_46788586 0.18 ENST00000542575.6
solute carrier family 1 member 5
chr2_+_108288869 0.18 ENST00000251481.11
ENST00000438339.5
ENST00000409880.5
ENST00000437390.6
sulfotransferase family 1C member 2
chr16_+_15949597 0.18 ENST00000399410.8
ATP binding cassette subfamily C member 1
chr16_-_2210833 0.18 ENST00000562360.5
ENST00000328540.8
ENST00000566018.1
BRICHOS domain containing 5
chr17_-_76103690 0.18 ENST00000411744.6
ENST00000634349.1
ENST00000332065.9
ENST00000607838.5
exocyst complex component 7
chr16_+_31033513 0.17 ENST00000313843.8
syntaxin 4
chr20_+_57329801 0.17 ENST00000371263.8
ENST00000345868.8
ENST00000371260.8
ENST00000418127.5
SPO11 initiator of meiotic double stranded breaks
chr1_-_39691450 0.17 ENST00000612703.3
ENST00000617690.2
hippocalcin like 4
chr19_-_12723925 0.17 ENST00000425528.6
ENST00000589337.5
ENST00000588216.5
transportin 2
chr12_+_113221429 0.17 ENST00000551096.5
ENST00000551099.5
ENST00000552897.5
ENST00000550785.5
ENST00000549279.1
ENST00000335509.11
two pore segment channel 1
chr3_-_122564253 0.17 ENST00000492382.5
ENST00000682323.1
ENST00000462315.5
poly(ADP-ribose) polymerase family member 9
chr16_+_28822982 0.17 ENST00000336783.9
ENST00000340394.12
ENST00000325215.10
ENST00000382686.8
ENST00000395547.6
ENST00000564304.5
ataxin 2 like
chr3_+_45030130 0.16 ENST00000428034.1
C-type lectin domain family 3 member B
chr11_-_6603571 0.16 ENST00000534343.1
ENST00000254605.11
ribosomal RNA processing 8
chr19_+_13150386 0.16 ENST00000292433.4
ENST00000587885.1
immediate early response 2
chr7_+_144048948 0.16 ENST00000641693.1
olfactory receptor family 2 subfamily A member 5
chr2_+_38666059 0.16 ENST00000272252.10
ENST00000410063.5
galactose mutarotase
chr17_-_76103714 0.15 ENST00000406660.4
ENST00000335146.11
ENST00000405575.8
ENST00000589210.6
exocyst complex component 7
chr15_+_41559189 0.15 ENST00000263798.8
TYRO3 protein tyrosine kinase
chr12_+_56158343 0.15 ENST00000548580.5
ENST00000293422.9
ENST00000348108.8
ENST00000549017.5
ENST00000549566.5
ENST00000550697.6
ENST00000536128.5
ENST00000547649.5
ENST00000547408.5
ENST00000551589.5
ENST00000549392.5
ENST00000548400.5
ENST00000548293.5
myosin light chain 6
chr1_+_91949395 0.15 ENST00000449584.5
ENST00000427104.5
ENST00000355011.7
ENST00000399546.7
ENST00000450792.5
ENST00000548992.5
ENST00000552654.1
ENST00000457265.1
bromodomain testis associated
chr14_-_102305179 0.15 ENST00000524214.5
MOK protein kinase
chr20_+_41136944 0.15 ENST00000244007.7
phospholipase C gamma 1
chr12_-_6470643 0.15 ENST00000535180.5
ENST00000400911.7
vesicle associated membrane protein 1
chr18_-_47023927 0.14 ENST00000675219.1
elongin A3 family member B
chr5_-_83673544 0.14 ENST00000503117.1
ENST00000510978.5
hyaluronan and proteoglycan link protein 1
chr11_+_113908983 0.14 ENST00000537778.5
5-hydroxytryptamine receptor 3B

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0045062 extrathymic T cell selection(GO:0045062)
0.6 1.9 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.5 3.0 GO:0006196 AMP catabolic process(GO:0006196) adenosine biosynthetic process(GO:0046086)
0.4 2.6 GO:0007296 vitellogenesis(GO:0007296)
0.4 2.7 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.4 1.4 GO:0042369 vitamin D catabolic process(GO:0042369)
0.3 1.0 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.2 1.4 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.2 0.7 GO:0014876 response to injury involved in regulation of muscle adaptation(GO:0014876)
0.2 0.6 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.2 0.7 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.4 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.1 0.4 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.4 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.1 15.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 0.5 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 0.9 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.1 0.9 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 0.3 GO:0051039 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.1 0.5 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 0.8 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.3 GO:0098976 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 0.6 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 0.2 GO:1990918 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.1 0.9 GO:0051026 chiasma assembly(GO:0051026)
0.1 0.4 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.1 0.5 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1 0.4 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.1 0.3 GO:1990523 bone regeneration(GO:1990523)
0.1 0.2 GO:0034963 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.1 0.7 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 0.4 GO:0061107 seminal vesicle development(GO:0061107)
0.1 0.3 GO:0042361 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.1 0.6 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 1.4 GO:0072520 seminiferous tubule development(GO:0072520)
0.1 0.3 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 1.3 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.1 0.2 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.1 0.6 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.1 1.5 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.1 0.8 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.1 0.2 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.0 0.4 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.3 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.5 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.4 GO:0070305 response to cGMP(GO:0070305)
0.0 0.2 GO:0010585 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.7 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.8 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.0 0.8 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.4 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.0 1.1 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.5 GO:1903764 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.2 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.4 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.2 GO:1903936 cellular response to sodium arsenite(GO:1903936)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.6 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.3 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.2 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.3 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.6 GO:0097296 activation of NF-kappaB-inducing kinase activity(GO:0007250) activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0 0.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.5 GO:0051923 sulfation(GO:0051923)
0.0 0.2 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.0 0.6 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.7 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.3 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.0 0.7 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.2 GO:1903416 response to glycoside(GO:1903416)
0.0 1.1 GO:0019835 cytolysis(GO:0019835)
0.0 0.3 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.6 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.2 GO:0060068 vagina development(GO:0060068)
0.0 0.4 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:0050960 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.8 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 0.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.0 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 1.1 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.2 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.5 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.6 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.3 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:0014062 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198) regulation of serotonin secretion(GO:0014062)
0.0 2.0 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.1 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.3 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.3 GO:0050718 positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0 0.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 1.3 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 0.0 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.1 GO:2000254 regulation of male germ cell proliferation(GO:2000254)
0.0 0.1 GO:0051873 killing by host of symbiont cells(GO:0051873)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 1.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.4 GO:0097443 sorting endosome(GO:0097443)
0.1 0.4 GO:0098855 HCN channel complex(GO:0098855)
0.1 1.1 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.4 GO:0036030 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.1 0.4 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.1 1.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.6 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.4 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.4 GO:0001652 granular component(GO:0001652)
0.1 0.6 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.8 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.6 GO:0005638 lamin filament(GO:0005638)
0.1 0.4 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 1.1 GO:0043219 lateral loop(GO:0043219)
0.0 2.7 GO:0043034 costamere(GO:0043034)
0.0 0.5 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.5 GO:0036128 CatSper complex(GO:0036128)
0.0 0.3 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 1.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.3 GO:0070449 elongin complex(GO:0070449)
0.0 0.4 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.7 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.3 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.6 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 2.6 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.1 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 1.4 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 2.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.9 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122) endolysosome membrane(GO:0036020)
0.0 0.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 2.3 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.4 1.3 GO:0000248 C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704)
0.3 1.3 GO:0070404 NADH binding(GO:0070404)
0.3 1.4 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.2 1.4 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.2 1.4 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.2 0.6 GO:0045569 TRAIL binding(GO:0045569)
0.1 0.7 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.1 3.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.5 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.4 GO:0015198 oligopeptide transporter activity(GO:0015198) oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.3 GO:0032090 Pyrin domain binding(GO:0032090)
0.1 0.5 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.5 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.5 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 0.6 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.1 0.4 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 0.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.3 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.2 GO:0036009 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.1 0.4 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.7 GO:0089720 death effector domain binding(GO:0035877) caspase binding(GO:0089720)
0.1 1.0 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 15.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 0.3 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 1.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.2 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 1.3 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.3 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.9 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 1.1 GO:0019841 retinol binding(GO:0019841)
0.0 0.2 GO:0005163 nerve growth factor receptor binding(GO:0005163)
0.0 0.2 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.4 GO:0032190 acrosin binding(GO:0032190)
0.0 0.5 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.4 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) PH domain binding(GO:0042731)
0.0 0.1 GO:0031716 calcitonin receptor activity(GO:0004948) calcitonin receptor binding(GO:0031716)
0.0 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.5 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.6 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.5 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.9 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.5 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.7 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:1990239 steroid hormone binding(GO:1990239)
0.0 0.0 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.0 0.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 2.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.8 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 1.5 GO:0019888 protein phosphatase regulator activity(GO:0019888)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 1.8 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 2.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 3.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.4 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.6 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.8 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.3 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.6 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.4 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.8 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.1 ST ADRENERGIC Adrenergic Pathway
0.0 0.1 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 0.5 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.8 REACTOME KINESINS Genes involved in Kinesins
0.0 1.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.4 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.3 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.9 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 0.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.8 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.0 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 1.6 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.1 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.3 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling