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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for ZBTB18

Z-value: 0.94

Motif logo

Transcription factors associated with ZBTB18

Gene Symbol Gene ID Gene Info
ENSG00000179456.10 ZBTB18

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB18hg38_v1_chr1_+_244051275_244051291-0.867.3e-10Click!

Activity profile of ZBTB18 motif

Sorted Z-values of ZBTB18 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB18

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_16980607 4.96 ENST00000375535.4
microfibril associated protein 2
chr7_+_101127095 3.89 ENST00000223095.5
serpin family E member 1
chr11_-_123195208 3.25 ENST00000448775.4
CXADR like membrane protein
chr4_+_74445302 2.91 ENST00000502307.1
amphiregulin
chr2_+_113127588 2.84 ENST00000409930.4
interleukin 1 receptor antagonist
chr4_+_74445126 2.80 ENST00000395748.8
amphiregulin
chr2_-_1744442 2.79 ENST00000433670.5
ENST00000425171.1
ENST00000252804.9
peroxidasin
chr15_-_74209019 2.60 ENST00000323940.9
signaling receptor and transporter of retinol STRA6
chr11_-_62556230 2.39 ENST00000530285.5
AHNAK nucleoprotein
chr3_-_111595339 2.26 ENST00000317012.5
zinc finger BED-type containing 2
chr9_+_122375286 2.12 ENST00000373698.7
prostaglandin-endoperoxide synthase 1
chr18_+_24155938 1.99 ENST00000582229.1
calcium binding tyrosine phosphorylation regulated
chrX_+_150983350 1.84 ENST00000455596.5
ENST00000448905.6
high mobility group box 3
chr17_-_43022350 1.70 ENST00000587173.5
ENST00000355653.8
vesicle amine transport 1
chr2_+_33134620 1.69 ENST00000402934.5
ENST00000404525.5
ENST00000407925.5
latent transforming growth factor beta binding protein 1
chr8_-_48921419 1.66 ENST00000020945.4
snail family transcriptional repressor 2
chr2_+_33134579 1.62 ENST00000418533.6
latent transforming growth factor beta binding protein 1
chrX_+_100644183 1.49 ENST00000640889.1
ENST00000373004.5
sushi repeat containing protein X-linked 2
chr11_+_5389377 1.42 ENST00000328611.5
olfactory receptor family 51 subfamily M member 1
chr5_-_151924846 1.36 ENST00000274576.9
glycine receptor alpha 1
chrX_+_43656289 1.34 ENST00000338702.4
monoamine oxidase A
chr5_-_151924824 1.32 ENST00000455880.2
glycine receptor alpha 1
chr11_-_101583985 1.30 ENST00000344327.8
transient receptor potential cation channel subfamily C member 6
chr3_+_100492548 1.25 ENST00000323523.8
ENST00000403410.5
ENST00000449609.1
transmembrane protein 45A
chr19_-_35510384 1.24 ENST00000602679.5
ENST00000492341.6
ENST00000472252.6
ENST00000602781.5
ENST00000402589.6
ENST00000458071.5
ENST00000436012.5
ENST00000443640.5
ENST00000450261.1
ENST00000467637.5
ENST00000480502.5
ENST00000474928.5
ENST00000414866.6
ENST00000392206.6
ENST00000488892.5
dermokine
chr9_+_113501359 1.21 ENST00000343817.9
ENST00000394646.7
regulator of G protein signaling 3
chr10_+_103493931 1.20 ENST00000369780.8
neuralized E3 ubiquitin protein ligase 1
chr14_-_91244669 1.18 ENST00000650645.1
G protein-coupled receptor 68
chr11_+_65638085 1.18 ENST00000534313.6
ENST00000533361.1
ENST00000526137.1
signal-induced proliferation-associated 1
chr17_+_62627628 1.14 ENST00000303375.10
mannose receptor C type 2
chr14_+_94110728 1.10 ENST00000616764.4
ENST00000618863.1
ENST00000611954.4
ENST00000618200.4
ENST00000621160.4
ENST00000555819.5
ENST00000620396.4
ENST00000612813.4
ENST00000620066.1
interferon alpha inducible protein 27
chr4_-_151227881 1.08 ENST00000652233.1
ENST00000514152.5
SH3 domain containing 19
chr6_+_41637005 1.07 ENST00000419164.6
ENST00000373051.6
MyoD family inhibitor
chr6_-_30556477 1.06 ENST00000376621.8
G protein nucleolar 1 (putative)
chr12_+_112125531 1.00 ENST00000549358.5
ENST00000257604.9
ENST00000548092.5
ENST00000412615.7
ENST00000552896.1
TRAF-type zinc finger domain containing 1
chr14_+_78170336 1.00 ENST00000634499.2
ENST00000335750.7
neurexin 3
chr10_+_5196831 0.98 ENST00000263126.3
aldo-keto reductase family 1 member C4
chr2_-_162243375 0.98 ENST00000188790.9
ENST00000443424.5
fibroblast activation protein alpha
chr22_+_20917398 0.98 ENST00000354336.8
CRK like proto-oncogene, adaptor protein
chr10_-_69573416 0.96 ENST00000242462.5
neurogenin 3
chr15_+_55319202 0.95 ENST00000164305.10
ENST00000566999.5
ENST00000539642.5
phosphatidylinositol glycan anchor biosynthesis class B
chr11_+_76783349 0.94 ENST00000333090.5
tsukushi, small leucine rich proteoglycan
chr17_-_78360066 0.92 ENST00000587578.1
ENST00000330871.3
suppressor of cytokine signaling 3
chr13_-_60013178 0.91 ENST00000498416.2
ENST00000465066.5
diaphanous related formin 3
chr6_-_162727748 0.91 ENST00000366892.5
ENST00000366898.6
ENST00000366897.5
ENST00000366896.5
ENST00000674250.1
parkin RBR E3 ubiquitin protein ligase
chr17_+_38428456 0.85 ENST00000622683.5
ENST00000620417.4
Rho GTPase activating protein 23
chr15_-_55319107 0.83 ENST00000565225.1
ENST00000436697.3
ENST00000567948.1
ENST00000563262.5
PIGB opposite strand 1
RAB27A, member RAS oncogene family
chr11_-_34357994 0.82 ENST00000435224.3
ankyrin repeat and BTB domain containing 2
chr13_-_33205997 0.82 ENST00000399365.7
StAR related lipid transfer domain containing 13
chrX_+_150983299 0.81 ENST00000325307.12
high mobility group box 3
chr10_-_93482194 0.81 ENST00000358334.9
ENST00000371488.3
myoferlin
chr2_-_162242998 0.81 ENST00000627638.2
ENST00000447386.5
fibroblast activation protein alpha
chr3_-_37174578 0.79 ENST00000336686.9
LRR binding FLII interacting protein 2
chr4_+_15374541 0.79 ENST00000382383.7
ENST00000429690.5
C1q and TNF related 7
chr18_+_3448456 0.79 ENST00000549780.5
TGFB induced factor homeobox 1
chr12_-_54391270 0.78 ENST00000352268.10
ENST00000549962.5
ENST00000338010.9
ENST00000550774.5
zinc finger protein 385A
chr14_+_64504574 0.76 ENST00000358738.3
zinc finger and BTB domain containing 1
chr12_-_104050112 0.74 ENST00000547583.1
ENST00000546851.1
ENST00000360814.9
glycosyltransferase 8 domain containing 2
chr1_+_204073104 0.73 ENST00000367204.6
SRY-box transcription factor 13
chr18_+_79863668 0.73 ENST00000316249.3
potassium voltage-gated channel modifier subfamily G member 2
chr10_+_11164961 0.72 ENST00000399850.7
ENST00000417956.6
CUGBP Elav-like family member 2
chr21_-_32813695 0.72 ENST00000479548.2
ENST00000490358.5
chromosome 21 open reading frame 62
chr2_-_88992903 0.71 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr2_-_65432591 0.71 ENST00000356388.9
sprouty related EVH1 domain containing 2
chr3_-_52239082 0.70 ENST00000499914.2
ENST00000678838.1
ENST00000305533.10
ENST00000678330.1
twinfilin actin binding protein 2
chr19_+_39412650 0.68 ENST00000425673.6
pleckstrin homology and RhoGEF domain containing G2
chr10_+_96304392 0.67 ENST00000630152.1
DNA nucleotidylexotransferase
chr16_-_30382805 0.66 ENST00000321367.7
ENST00000652617.1
septin 1
chr10_+_96304425 0.66 ENST00000371174.5
DNA nucleotidylexotransferase
chr15_-_31160954 0.60 ENST00000558445.5
ENST00000559177.5
transient receptor potential cation channel subfamily M member 1
chr2_-_85602351 0.59 ENST00000409668.1
transmembrane protein 150A
chr1_+_15684284 0.59 ENST00000375799.8
ENST00000375793.2
pleckstrin homology and RUN domain containing M2
chr16_-_29862890 0.58 ENST00000563415.1
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr8_+_39107529 0.58 ENST00000399831.7
ENST00000437682.6
ENST00000519315.5
ADAM metallopeptidase domain 32
chr16_+_6019585 0.54 ENST00000547372.5
RNA binding fox-1 homolog 1
chr17_+_50561010 0.54 ENST00000360761.8
ENST00000354983.8
ENST00000352832.9
calcium voltage-gated channel subunit alpha1 G
chr2_-_85602681 0.54 ENST00000334462.10
ENST00000306353.7
transmembrane protein 150A
chr17_-_33293247 0.53 ENST00000225823.7
acid sensing ion channel subunit 2
chr3_+_159852933 0.51 ENST00000482804.1
schwannomin interacting protein 1
chr20_+_58907981 0.51 ENST00000656419.1
GNAS complex locus
chr15_-_74208969 0.50 ENST00000423167.6
ENST00000432245.6
signaling receptor and transporter of retinol STRA6
chr2_+_201129318 0.49 ENST00000417748.1
CASP8 and FADD like apoptosis regulator
chrX_+_9912434 0.49 ENST00000418909.6
shroom family member 2
chr11_+_15114912 0.49 ENST00000379556.8
INSC spindle orientation adaptor protein
chr15_-_31161157 0.48 ENST00000542188.5
transient receptor potential cation channel subfamily M member 1
chr11_-_94493863 0.47 ENST00000323977.7
ENST00000536754.5
MRE11 homolog, double strand break repair nuclease
chr4_+_155903688 0.46 ENST00000536354.3
tryptophan 2,3-dioxygenase
chr6_+_160121859 0.46 ENST00000324965.8
ENST00000457470.6
solute carrier family 22 member 1
chr17_+_44349050 0.46 ENST00000639447.1
granulin precursor
chr19_-_15808126 0.44 ENST00000334920.3
olfactory receptor family 10 subfamily H member 1
chr6_+_160121809 0.44 ENST00000366963.9
solute carrier family 22 member 1
chr1_+_186296267 0.42 ENST00000533951.5
ENST00000367482.8
ENST00000635041.1
ENST00000367483.8
ENST00000367485.4
ENST00000445192.7
proteoglycan 4
chr20_+_31879798 0.41 ENST00000620043.4
tubulin tyrosine ligase like 9
chr20_+_59300703 0.41 ENST00000395654.3
endothelin 3
chr18_+_54828406 0.40 ENST00000262094.10
RAB27B, member RAS oncogene family
chr16_-_87334273 0.40 ENST00000568879.1
novel protein
chr14_+_67240713 0.39 ENST00000677382.1
membrane palmitoylated protein 5
chr3_+_121593363 0.38 ENST00000338040.6
F-box protein 40
chr11_+_5488685 0.38 ENST00000322641.5
olfactory receptor family 52 subfamily D member 1
chr2_-_74465162 0.38 ENST00000649854.1
ENST00000650523.1
ENST00000649601.1
ENST00000448666.7
ENST00000409065.5
ENST00000414701.1
ENST00000452063.7
ENST00000649075.1
ENST00000648810.1
ENST00000462443.2
mannosyl-oligosaccharide glucosidase
chr8_+_21966215 0.37 ENST00000433566.8
exportin 7
chr7_+_95485898 0.37 ENST00000428113.5
ankyrin repeat and SOCS box containing 4
chr16_-_49664225 0.36 ENST00000535559.5
zinc finger protein 423
chr9_+_70043840 0.36 ENST00000377182.5
MAM domain containing 2
chr12_+_2053311 0.35 ENST00000399617.6
ENST00000683482.1
calcium voltage-gated channel subunit alpha1 C
chrX_+_124346525 0.34 ENST00000360027.4
SH2 domain containing 1A
chr20_+_59300589 0.34 ENST00000337938.7
ENST00000371025.7
endothelin 3
chrX_+_48383516 0.33 ENST00000620320.4
ENST00000595689.3
SSX family member 4
chrX_+_124346571 0.33 ENST00000477673.2
SH2 domain containing 1A
chr14_+_67241278 0.30 ENST00000676464.1
membrane palmitoylated protein 5
chr11_-_57322197 0.29 ENST00000532437.1
tankyrase 1 binding protein 1
chr19_+_42269219 0.29 ENST00000681038.1
capicua transcriptional repressor
chr2_+_188974364 0.29 ENST00000304636.9
ENST00000317840.9
collagen type III alpha 1 chain
chr11_-_69013356 0.29 ENST00000441623.1
MAS related GPR family member F
chr1_+_23743462 0.29 ENST00000609199.1
elongin A
chr15_+_51377247 0.29 ENST00000396399.6
gliomedin
chr10_-_22003678 0.28 ENST00000376980.8
DnaJ heat shock protein family (Hsp40) member C1
chr19_+_40613416 0.28 ENST00000599724.5
ENST00000597071.5
latent transforming growth factor beta binding protein 4
chr1_-_151909501 0.27 ENST00000368814.8
thioesterase superfamily member 4
chrX_+_103776831 0.27 ENST00000621218.5
ENST00000619236.1
proteolipid protein 1
chr11_+_60056653 0.26 ENST00000278865.8
membrane spanning 4-domains A3
chr1_+_77888612 0.25 ENST00000334785.12
nexilin F-actin binding protein
chr3_-_160449752 0.25 ENST00000496222.1
ENST00000471396.1
ENST00000471155.5
ENST00000309784.9
tripartite motif containing 59
chr11_+_60056587 0.25 ENST00000395032.6
ENST00000358152.6
membrane spanning 4-domains A3
chr5_+_132673983 0.24 ENST00000622422.1
ENST00000231449.7
ENST00000350025.2
interleukin 4
chr11_+_73289403 0.24 ENST00000535931.2
ENST00000544437.6
pyrimidinergic receptor P2Y6
chr4_+_87650277 0.23 ENST00000339673.11
ENST00000282479.8
dentin matrix acidic phosphoprotein 1
chr4_-_110641920 0.23 ENST00000354925.6
ENST00000511990.1
ENST00000613094.4
ENST00000614423.4
ENST00000616641.4
ENST00000511837.5
paired like homeodomain 2
chr12_+_25973748 0.23 ENST00000542865.5
Ras association domain family member 8
chr11_-_94493798 0.23 ENST00000538923.1
ENST00000540013.5
ENST00000407439.7
ENST00000323929.8
ENST00000393241.8
MRE11 homolog, double strand break repair nuclease
chr17_+_50560703 0.22 ENST00000359106.10
calcium voltage-gated channel subunit alpha1 G
chr3_-_160449721 0.21 ENST00000479460.5
tripartite motif containing 59
chr1_-_151909555 0.20 ENST00000489410.1
thioesterase superfamily member 4
chr17_-_63972918 0.20 ENST00000435607.3
sodium voltage-gated channel alpha subunit 4
chr12_-_102481744 0.20 ENST00000644491.1
insulin like growth factor 1
chr3_-_160449530 0.20 ENST00000494486.1
tripartite motif containing 59
chrX_+_103776493 0.19 ENST00000433491.5
ENST00000612423.4
ENST00000443502.5
proteolipid protein 1
chr14_-_38256074 0.19 ENST00000342213.3
C-type lectin domain containing 14A
chr13_+_113122791 0.19 ENST00000375559.8
ENST00000409306.5
ENST00000375551.7
coagulation factor X
chr20_+_59300547 0.18 ENST00000644821.1
endothelin 3
chr19_+_9140377 0.18 ENST00000360385.7
ENST00000247956.11
zinc finger protein 317
chr5_-_149944744 0.18 ENST00000255266.10
ENST00000617647.4
ENST00000613228.1
phosphodiesterase 6A
chr13_-_46390042 0.18 ENST00000389908.7
rubicon like autophagy enhancer
chr1_-_156677400 0.17 ENST00000368223.4
nestin
chrX_+_124346544 0.16 ENST00000371139.9
SH2 domain containing 1A
chr3_+_124584625 0.16 ENST00000291478.9
ENST00000682363.1
ENST00000454902.1
kalirin RhoGEF kinase
chr1_+_77888490 0.16 ENST00000401035.7
ENST00000330010.12
nexilin F-actin binding protein
chr19_-_42302292 0.15 ENST00000594989.5
platelet activating factor acetylhydrolase 1b catalytic subunit 3
chr11_+_32091065 0.15 ENST00000054950.4
reticulocalbin 1
chr1_-_207032749 0.15 ENST00000359470.6
ENST00000461135.2
chromosome 1 open reading frame 116
chr8_+_24384275 0.15 ENST00000256412.8
ADAM like decysin 1
chr19_-_51645545 0.15 ENST00000534261.3
sialic acid binding Ig like lectin 5
chr11_-_69013233 0.15 ENST00000309099.7
ENST00000320913.6
MAS related GPR family member F
chr19_+_50432885 0.14 ENST00000357701.6
myosin binding protein C2
chr14_-_23057530 0.14 ENST00000397359.7
ENST00000610348.1
cadherin 24
chrX_-_111270474 0.13 ENST00000324068.2
calpain 6
chr16_-_29899245 0.13 ENST00000537485.5
seizure related 6 homolog like 2
chr5_+_132873660 0.12 ENST00000296877.3
liver enriched antimicrobial peptide 2
chr22_+_41976760 0.12 ENST00000396426.7
ENST00000406029.5
septin 3
chr20_+_59300402 0.12 ENST00000311585.11
ENST00000371028.6
endothelin 3
chr7_-_122699108 0.11 ENST00000340112.3
ring finger protein 133
chr17_+_79024142 0.11 ENST00000579760.6
ENST00000339142.6
C1q and TNF related 1
chr7_-_95324524 0.11 ENST00000222381.8
paraoxonase 1
chr8_+_103819244 0.11 ENST00000262231.14
ENST00000507740.5
ENST00000408894.6
regulating synaptic membrane exocytosis 2
chr1_-_168729187 0.10 ENST00000367817.4
dermatopontin
chr22_+_41976933 0.10 ENST00000396425.7
septin 3
chr16_-_67150951 0.10 ENST00000449549.4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr14_-_23057506 0.10 ENST00000487137.7
cadherin 24
chr12_+_2052977 0.09 ENST00000399634.6
ENST00000406454.8
ENST00000327702.12
ENST00000347598.9
ENST00000399603.6
ENST00000399641.6
ENST00000399655.6
ENST00000335762.10
ENST00000682835.1
calcium voltage-gated channel subunit alpha1 C
chr17_+_34285734 0.09 ENST00000305869.4
C-C motif chemokine ligand 11
chr19_+_11538844 0.09 ENST00000252456.7
calponin 1
chr2_+_151357583 0.09 ENST00000243347.5
TNF alpha induced protein 6
chr9_+_84668485 0.08 ENST00000359847.4
ENST00000395882.6
ENST00000376208.6
ENST00000376213.6
neurotrophic receptor tyrosine kinase 2
chr7_+_95485934 0.07 ENST00000325885.6
ankyrin repeat and SOCS box containing 4
chr11_+_63888515 0.07 ENST00000509502.6
ENST00000512060.1
microtubule affinity regulating kinase 2
chr8_+_24384455 0.06 ENST00000522298.1
ADAM like decysin 1
chr3_+_184176778 0.06 ENST00000439647.5
adaptor related protein complex 2 subunit mu 1
chr19_+_38390055 0.06 ENST00000587947.5
ENST00000338502.8
sprouty related EVH1 domain containing 3
chr17_+_44308573 0.06 ENST00000590941.5
ENST00000225441.11
ENST00000426726.8
RUN domain containing 3A
chr15_+_31326807 0.04 ENST00000307145.4
Kruppel like factor 13
chr11_+_59713403 0.04 ENST00000641815.1
syntaxin 3
chr19_+_11538767 0.04 ENST00000592923.5
ENST00000535659.6
calponin 1
chr17_+_49575828 0.02 ENST00000328741.6
neurexophilin 3
chr11_-_63917129 0.01 ENST00000301459.5
REST corepressor 2
chr17_-_69141878 0.01 ENST00000590645.1
ENST00000284425.7
ATP binding cassette subfamily A member 6
chr16_-_29863117 0.01 ENST00000566113.5
ENST00000569956.5
ENST00000570016.5
ENST00000219789.11
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr19_+_49581304 0.00 ENST00000246794.10
proline rich and Gla domain 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:2000097 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.9 1.8 GO:0097325 melanocyte proliferation(GO:0097325)
0.7 5.0 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.6 5.7 GO:0060750 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.6 1.7 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273) negative regulation of response to alcohol(GO:1901420)
0.5 3.1 GO:0061143 alveolar primary septum development(GO:0061143)
0.5 3.3 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.4 1.2 GO:0042631 cellular response to water deprivation(GO:0042631)
0.4 2.7 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.4 2.8 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.3 1.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.3 0.9 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.2 0.9 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.2 0.9 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 1.7 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.2 0.8 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.2 0.7 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.2 1.0 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 0.8 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.8 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 1.2 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.1 1.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 1.0 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 0.9 GO:0048241 epinephrine transport(GO:0048241)
0.1 0.2 GO:0071288 cellular response to mercury ion(GO:0071288)
0.1 0.6 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 1.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 2.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 1.0 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.5 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 0.7 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.7 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.1 1.3 GO:0042420 dopamine catabolic process(GO:0042420)
0.1 0.2 GO:0060127 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.1 2.8 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 1.3 GO:0006828 manganese ion transport(GO:0006828)
0.1 0.7 GO:0032532 regulation of microvillus length(GO:0032532)
0.1 1.1 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.1 1.2 GO:0086045 membrane depolarization during AV node cell action potential(GO:0086045)
0.1 2.0 GO:0048240 sperm capacitation(GO:0048240)
0.1 1.2 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.5 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.5 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.8 GO:0001778 plasma membrane repair(GO:0001778)
0.0 1.0 GO:0060290 transdifferentiation(GO:0060290)
0.0 1.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 1.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:1904073 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.9 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 2.4 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.1 GO:0034445 negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.5 GO:0045176 apical protein localization(GO:0045176)
0.0 0.8 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.5 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.1 GO:0035962 response to interleukin-13(GO:0035962)
0.0 1.0 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.4 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 1.3 GO:0033198 response to ATP(GO:0033198)
0.0 0.1 GO:2000176 pro-T cell differentiation(GO:0002572) regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.0 0.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.8 GO:0097237 cellular response to toxic substance(GO:0097237)
0.0 0.6 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.2 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.5 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 2.6 GO:0032392 DNA geometric change(GO:0032392)
0.0 0.7 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 1.1 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 3.2 GO:0048565 digestive tract development(GO:0048565)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.0 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 2.2 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 1.1 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.3 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 1.1 GO:0002456 T cell mediated immunity(GO:0002456)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0097229 sperm end piece(GO:0097229)
0.3 8.3 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.2 1.1 GO:0035841 new growing cell tip(GO:0035841)
0.1 0.9 GO:0071797 LUBAC complex(GO:0071797) Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 2.7 GO:0060077 inhibitory synapse(GO:0060077)
0.1 1.8 GO:0071438 invadopodium membrane(GO:0071438)
0.1 1.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.8 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.7 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.7 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 1.2 GO:0097440 apical dendrite(GO:0097440)
0.0 0.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 3.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 2.4 GO:0043034 costamere(GO:0043034)
0.0 4.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 3.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:0070449 elongin complex(GO:0070449)
0.0 1.3 GO:0000791 euchromatin(GO:0000791)
0.0 0.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 2.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 2.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 1.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.6 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.7 3.3 GO:0050436 microfibril binding(GO:0050436)
0.5 2.7 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.4 2.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.3 0.8 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.2 1.0 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.2 0.9 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.2 0.7 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 1.0 GO:0031708 endothelin B receptor binding(GO:0031708)
0.2 0.9 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.1 1.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.5 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 1.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.5 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 2.4 GO:0044548 S100 protein binding(GO:0044548)
0.1 2.6 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 5.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.9 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 1.8 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 0.6 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.5 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 1.2 GO:0031489 myosin V binding(GO:0031489)
0.0 0.7 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 1.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 1.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 1.0 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 1.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.8 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.5 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 3.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.8 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.5 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.4 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.4 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.9 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 1.2 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.7 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 1.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.7 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 3.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 3.2 PID EPO PATHWAY EPO signaling pathway
0.0 5.3 PID NOTCH PATHWAY Notch signaling pathway
0.0 2.8 PID IL1 PATHWAY IL1-mediated signaling events
0.0 2.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 8.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.3 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.9 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.3 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.8 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.2 PID PDGFRB PATHWAY PDGFR-beta signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 4.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 1.0 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 2.7 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 0.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 2.8 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.9 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.9 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.5 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.0 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 1.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 2.1 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.4 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 1.2 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 1.0 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 2.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 2.3 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling