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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for ZBTB49

Z-value: 0.41

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Transcription factors associated with ZBTB49

Gene Symbol Gene ID Gene Info
ENSG00000168826.16 ZBTB49

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB49hg38_v1_chr4_+_4290216_4290284-0.067.6e-01Click!

Activity profile of ZBTB49 motif

Sorted Z-values of ZBTB49 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB49

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_+_761073 1.10 ENST00000382862.7
ENST00000563651.5
mesothelin
chr9_-_94640248 1.05 ENST00000415431.5
fructose-bisphosphatase 1
chr16_+_760728 0.99 ENST00000545450.7
ENST00000563941.5
ENST00000566549.5
mesothelin
chr9_-_94640130 0.82 ENST00000414122.1
fructose-bisphosphatase 1
chr9_-_94639473 0.79 ENST00000375326.9
fructose-bisphosphatase 1
chr1_+_78649818 0.63 ENST00000370747.9
ENST00000438486.1
interferon induced protein 44
chr8_+_24294044 0.45 ENST00000265769.9
ADAM metallopeptidase domain 28
chr14_+_79279403 0.31 ENST00000281127.11
neurexin 3
chr14_+_79279906 0.31 ENST00000428277.6
neurexin 3
chrX_-_56995508 0.31 ENST00000374919.6
ENST00000639007.1
ENST00000639583.1
ENST00000638289.1
ENST00000639525.1
ENST00000638386.1
spindlin family member 3
chr8_+_24294107 0.28 ENST00000437154.6
ADAM metallopeptidase domain 28
chrX_-_56995426 0.26 ENST00000640768.1
ENST00000638619.1
spindlin family member 3
chr1_+_46341164 0.25 ENST00000537428.2
NOP2/Sun RNA methyltransferase 4
chr20_+_5750437 0.24 ENST00000445603.1
ENST00000442185.1
shieldin complex subunit 1
chr22_-_28800042 0.23 ENST00000405219.7
X-box binding protein 1
chrX_-_153944621 0.23 ENST00000393700.8
renin binding protein
chr1_+_46340780 0.23 ENST00000474844.6
NOP2/Sun RNA methyltransferase 4
chrX_+_9463272 0.22 ENST00000407597.7
ENST00000380961.5
ENST00000424279.6
transducin beta like 1 X-linked
chr1_+_211326615 0.22 ENST00000336184.6
TNF receptor associated factor 5
chr7_+_151028422 0.21 ENST00000542328.5
ENST00000461373.5
ENST00000297504.10
ENST00000358849.9
ENST00000498578.5
ENST00000477719.5
ENST00000477092.5
ATP binding cassette subfamily B member 8
chrX_+_102599168 0.21 ENST00000246174.6
armadillo repeat containing X-linked 5
chr12_+_40225071 0.20 ENST00000680790.1
leucine rich repeat kinase 2
chr12_+_40224956 0.19 ENST00000298910.12
ENST00000343742.6
leucine rich repeat kinase 2
chr22_-_28800558 0.18 ENST00000403532.7
ENST00000611155.4
ENST00000216037.10
X-box binding protein 1
chr3_+_52198113 0.18 ENST00000310271.6
5'-aminolevulinate synthase 1
chr3_+_52198152 0.18 ENST00000484952.6
5'-aminolevulinate synthase 1
chr13_-_99971739 0.18 ENST00000267294.4
Zic family member 5
chrX_-_153944655 0.17 ENST00000369997.7
renin binding protein
chr1_-_1778399 0.17 ENST00000341426.9
NAD kinase
chr5_+_141094595 0.17 ENST00000622947.1
ENST00000194155.7
ENST00000624874.1
ENST00000625033.1
protocadherin beta 2
chr12_+_32106762 0.17 ENST00000551848.1
ENST00000652176.1
BICD cargo adaptor 1
chr3_+_52198086 0.16 ENST00000469224.5
ENST00000394965.6
5'-aminolevulinate synthase 1
chr1_-_1779976 0.16 ENST00000378625.5
NAD kinase
chr3_-_142578716 0.16 ENST00000661310.1
ENST00000350721.9
ATR serine/threonine kinase
chr14_+_24115299 0.16 ENST00000559354.5
ENST00000560459.5
ENST00000559593.5
ENST00000396941.8
ENST00000396936.5
DDB1 and CUL4 associated factor 11
chrX_+_30247139 0.15 ENST00000397548.4
MAGE family member B1
chr2_+_219206768 0.15 ENST00000289528.10
ENST00000409206.5
ENST00000444522.6
ENST00000621130.4
ENST00000409594.5
ENST00000422255.5
ENST00000409412.5
ENST00000409097.5
ENST00000409336.5
ENST00000409217.5
zinc finger AN1-type containing 2B
chr19_-_51108365 0.14 ENST00000421832.3
cytosolic thiouridylase subunit 1
chr19_+_49642188 0.14 ENST00000360565.8
SR-related CTD associated factor 1
chr12_+_50112028 0.14 ENST00000317943.6
cytochrome c oxidase assembly factor COX14
chr21_+_17513119 0.14 ENST00000356275.10
ENST00000400165.5
ENST00000400169.1
CXADR Ig-like cell adhesion molecule
chr19_+_57240610 0.13 ENST00000414468.3
zinc finger protein 805
chr12_+_123671105 0.13 ENST00000680574.1
ENST00000426174.6
ENST00000679504.1
ENST00000303372.7
tectonic family member 2
chr2_+_3595049 0.13 ENST00000236693.11
ENST00000349077.9
collectin subfamily member 11
chr14_+_24114627 0.13 ENST00000559115.5
ENST00000558215.5
ENST00000557810.5
ENST00000561375.5
ENST00000446197.8
ENST00000559796.5
ENST00000560713.5
ENST00000560901.5
ENST00000559382.5
ENST00000561001.5
DDB1 and CUL4 associated factor 11
chr10_+_88990736 0.12 ENST00000357339.6
ENST00000652046.1
ENST00000355279.2
Fas cell surface death receptor
chr14_-_93207007 0.12 ENST00000556566.1
ENST00000306954.5
GON7 subunit of KEOPS complex
chr11_-_2929412 0.11 ENST00000314222.5
pleckstrin homology like domain family A member 2
chr3_-_51779187 0.11 ENST00000398780.5
ENST00000668964.1
ENST00000667863.2
ENST00000647442.1
IQ motif containing F6
chr21_-_17612842 0.11 ENST00000339775.10
ENST00000348354.7
BTG anti-proliferation factor 3
chr9_-_7799752 0.10 ENST00000358227.5
distal membrane arm assembly complex 1
chrX_+_102599502 0.09 ENST00000473968.6
ENST00000604957.1
ENST00000477663.6
ENST00000479502.2
ENST00000602463.5
ENST00000465548.1
ENST00000460026.6
ENST00000475738.5
ENST00000466616.5
ENST00000602366.5
ENST00000476910.6
ENST00000486740.6
ENST00000460793.1
armadillo repeat containing X-linked 5
ARMCX5-GPRASP2 readthrough
chr4_-_42657085 0.09 ENST00000264449.14
ENST00000510289.1
ENST00000381668.9
ATPase phospholipid transporting 8A1
chr9_-_14693419 0.09 ENST00000380916.9
zinc finger DHHC-type palmitoyltransferase 21
chr4_-_163166822 0.09 ENST00000422287.6
ENST00000274054.3
nuclear assembly factor 1 ribonucleoprotein
chr12_+_53441724 0.08 ENST00000551003.5
ENST00000429243.7
ENST00000549068.5
ENST00000549740.5
ENST00000546581.5
ENST00000549581.5
ENST00000547368.5
ENST00000379786.8
ENST00000551945.5
ENST00000547717.1
proline rich 13
novel transcript
chr3_+_196942638 0.08 ENST00000602845.2
NCBP2 antisense 2 (head to head)
chr21_+_17513003 0.08 ENST00000284878.12
ENST00000400166.5
CXADR Ig-like cell adhesion molecule
chr2_-_85328262 0.07 ENST00000282120.6
trans-golgi network protein 2
chr2_-_85328232 0.07 ENST00000398263.6
trans-golgi network protein 2
chr16_-_57802401 0.07 ENST00000569112.5
ENST00000445690.7
ENST00000562311.5
ENST00000379655.8
kinesin family member C3
chr7_+_149239641 0.06 ENST00000335870.7
zinc finger protein 212
chr1_-_17439657 0.06 ENST00000375436.9
regulator of chromosome condensation 2
chr4_-_127965133 0.06 ENST00000641558.1
ENST00000641590.1
ENST00000641503.1
ENST00000641482.1
ENST00000641743.1
ENST00000641369.1
ENST00000641949.1
ENST00000641695.1
ENST00000641509.1
ENST00000641243.1
ENST00000641686.2
ENST00000641690.1
ENST00000641228.1
ENST00000642042.1
major facilitator superfamily domain containing 8
chr19_-_42390268 0.06 ENST00000597255.1
ENST00000222032.10
cornifelin
chr20_+_34546815 0.06 ENST00000374837.7
microtubule associated protein 1 light chain 3 alpha
chr2_-_85327963 0.06 ENST00000444342.2
ENST00000377386.8
ENST00000409232.7
ENST00000409015.5
trans-golgi network protein 2
chr22_-_42857194 0.06 ENST00000437119.6
ENST00000454099.5
ENST00000263245.10
ADP ribosylation factor GTPase activating protein 3
chr8_-_16186270 0.05 ENST00000445506.6
macrophage scavenger receptor 1
chr9_-_69014090 0.05 ENST00000377276.5
protein kinase cAMP-activated catalytic subunit gamma
chr3_+_42654470 0.05 ENST00000680014.1
zinc finger and BTB domain containing 47
chr20_+_3471003 0.05 ENST00000262919.10
ENST00000446916.2
attractin
chr4_-_127965204 0.05 ENST00000513559.6
ENST00000641186.1
ENST00000641393.1
major facilitator superfamily domain containing 8
chr14_-_24114913 0.04 ENST00000561028.6
ENST00000558280.1
neural retina leucine zipper
chr16_+_69132590 0.04 ENST00000562237.5
ENST00000567460.5
ENST00000566227.5
ENST00000314423.12
ENST00000352319.8
ENST00000563094.5
UTP4 small subunit processome component
chr4_-_52659238 0.04 ENST00000451218.6
ENST00000441222.8
ubiquitin specific peptidase 46
chr14_+_79279681 0.04 ENST00000679122.1
neurexin 3
chr9_+_131502789 0.04 ENST00000372228.9
ENST00000341012.13
ENST00000677216.1
ENST00000676640.1
ENST00000441334.5
ENST00000402686.8
ENST00000677029.1
ENST00000676915.1
ENST00000676803.1
ENST00000677293.1
ENST00000678303.1
ENST00000677626.1
ENST00000372220.5
ENST00000683229.1
ENST00000418774.6
ENST00000430619.2
ENST00000448212.5
ENST00000679221.1
ENST00000678785.1
protein O-mannosyltransferase 1
chr3_-_185254028 0.03 ENST00000440662.1
ENST00000456310.5
ENST00000231887.8
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
chr10_+_63133247 0.03 ENST00000435510.6
nuclear receptor binding factor 2
chr10_+_63133279 0.03 ENST00000277746.11
nuclear receptor binding factor 2
chr14_+_79279339 0.03 ENST00000557594.5
neurexin 3
chr8_+_1823918 0.03 ENST00000349830.8
Rho guanine nucleotide exchange factor 10
chr2_+_30447211 0.03 ENST00000466477.5
ENST00000465200.5
ENST00000319406.8
ENST00000379509.8
ENST00000488144.5
ENST00000465538.5
ENST00000309052.8
lysocardiolipin acyltransferase 1
chrX_-_154490614 0.02 ENST00000369649.8
ENST00000393586.1
ENST00000651600.1
solute carrier family 10 member 3
chr16_+_81035830 0.02 ENST00000299575.5
ATM interactor
chr11_+_94512452 0.02 ENST00000542198.3
chromosome 11 open reading frame 97
chr1_+_26432299 0.02 ENST00000427245.6
ENST00000236342.12
ENST00000525682.6
ENST00000526219.5
ENST00000374185.7
ENST00000360009.6
ENST00000533087.5
ENST00000531312.5
ENST00000525165.5
ENST00000525326.5
ENST00000525546.5
ENST00000436153.6
ENST00000530781.5
dehydrodolichyl diphosphate synthase subunit
chr1_-_36397880 0.02 ENST00000315732.3
LSM10, U7 small nuclear RNA associated
chr8_+_1823967 0.02 ENST00000520359.5
ENST00000518288.5
Rho guanine nucleotide exchange factor 10
chr5_+_154858218 0.02 ENST00000523698.5
ENST00000517876.5
ENST00000520472.5
CCR4-NOT transcription complex subunit 8
chr12_+_56007484 0.02 ENST00000262032.9
IKAROS family zinc finger 4
chr8_+_7825137 0.01 ENST00000335186.3
defensin beta 106A
chr22_-_41621014 0.01 ENST00000263256.7
desumoylating isopeptidase 1
chr5_+_154858594 0.01 ENST00000519430.5
ENST00000520671.5
ENST00000521583.5
ENST00000285896.11
ENST00000518028.5
ENST00000519404.5
ENST00000519394.5
ENST00000518775.5
CCR4-NOT transcription complex subunit 8
chr5_+_154858482 0.01 ENST00000519211.5
ENST00000522458.5
ENST00000519903.5
ENST00000521450.5
ENST00000403027.6
CCR4-NOT transcription complex subunit 8
chr15_-_55196899 0.01 ENST00000677147.1
ENST00000260443.9
ENST00000677730.1
ribosomal L24 domain containing 1
chr5_+_154858537 0.01 ENST00000517568.5
ENST00000524105.5
CCR4-NOT transcription complex subunit 8
chr7_-_103989516 0.01 ENST00000343529.9
ENST00000424685.3
reelin
chr9_-_113340248 0.01 ENST00000341761.8
ENST00000374195.7
ENST00000374193.9
WD repeat domain 31
chr22_-_21551461 0.01 ENST00000433039.2
RIMS binding protein 3C
chr19_-_19643597 0.01 ENST00000587205.1
ENST00000203556.9
GEM interacting protein
chr7_-_103989649 0.01 ENST00000428762.6
reelin
chr1_-_11691471 0.01 ENST00000376672.5
mitotic arrest deficient 2 like 2
chr16_-_75536071 0.00 ENST00000336257.8
carbohydrate sulfotransferase 5
chr8_-_98117155 0.00 ENST00000254878.8
ENST00000521560.1
reactive intermediate imine deaminase A homolog
chr22_-_18611919 0.00 ENST00000619918.1
RIMS binding protein 3
chr14_+_79280056 0.00 ENST00000676811.1
neurexin 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.1 0.4 GO:1903487 positive regulation of vascular wound healing(GO:0035470) regulation of lactation(GO:1903487)
0.1 0.4 GO:1903216 negative regulation of late endosome to lysosome transport(GO:1902823) regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.1 0.4 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.1 0.2 GO:1904868 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0 0.5 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.2 GO:0098904 regulation of AV node cell action potential(GO:0098904)
0.0 0.2 GO:1900276 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.0 0.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.5 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.7 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.1 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 1.7 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.1 GO:0036337 Fas signaling pathway(GO:0036337)
0.0 0.1 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0044753 amphisome(GO:0044753)
0.0 0.2 GO:0072517 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.0 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.2 0.5 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.1 0.4 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.1 0.5 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.7 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.2 GO:0032407 MutSalpha complex binding(GO:0032407)
0.0 0.0 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway