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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for ZIC3_ZIC4

Z-value: 0.67

Motif logo

Transcription factors associated with ZIC3_ZIC4

Gene Symbol Gene ID Gene Info
ENSG00000156925.12 ZIC3
ENSG00000174963.18 ZIC4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZIC3hg38_v1_chrX_+_137566119_137566167-0.337.5e-02Click!
ZIC4hg38_v1_chr3_-_147406520_1474065490.271.6e-01Click!

Activity profile of ZIC3_ZIC4 motif

Sorted Z-values of ZIC3_ZIC4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZIC3_ZIC4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_-_13099652 5.00 ENST00000378839.1
coiled-coil domain containing 3
chr12_+_49961864 3.76 ENST00000293599.7
aquaporin 5
chr5_-_180591488 3.67 ENST00000292641.4
secretoglobin family 3A member 1
chr5_+_77210881 2.96 ENST00000340978.7
ENST00000346042.7
ENST00000342343.8
ENST00000333194.8
phosphodiesterase 8B
chr5_+_77210667 2.70 ENST00000264917.10
phosphodiesterase 8B
chr8_+_1763766 2.46 ENST00000635751.1
ENST00000331222.6
ENST00000637156.1
ENST00000636934.1
ENST00000637083.1
CLN8 transmembrane ER and ERGIC protein
chr2_-_98936155 2.29 ENST00000428096.5
ENST00000397899.7
ENST00000420294.1
CRACD like
chr13_+_34942263 2.15 ENST00000379939.7
ENST00000400445.7
neurobeachin
chr7_-_117873420 2.14 ENST00000160373.8
cortactin binding protein 2
chr8_+_1763832 1.87 ENST00000520991.3
CLN8 transmembrane ER and ERGIC protein
chr4_-_148442342 1.85 ENST00000358102.8
nuclear receptor subfamily 3 group C member 2
chr4_-_148442508 1.82 ENST00000625323.2
nuclear receptor subfamily 3 group C member 2
chr11_+_2444986 1.76 ENST00000155840.12
potassium voltage-gated channel subfamily Q member 1
chr8_+_1763752 1.76 ENST00000519254.2
CLN8 transmembrane ER and ERGIC protein
chr17_-_76141240 1.68 ENST00000322957.7
forkhead box J1
chr6_-_89412219 1.59 ENST00000369415.9
Ras related GTP binding D
chr11_+_125951783 1.58 ENST00000640497.1
V-set and immunoglobulin domain containing 10 like 2
chr6_-_89412069 1.46 ENST00000359203.3
Ras related GTP binding D
chr4_-_148444674 1.27 ENST00000344721.8
nuclear receptor subfamily 3 group C member 2
chr11_-_67505323 1.23 ENST00000356404.8
ENST00000436757.6
phosphatidylinositol transfer protein membrane associated 1
chr6_-_29628038 1.11 ENST00000355973.7
ENST00000377012.8
gamma-aminobutyric acid type B receptor subunit 1
chr13_+_24680407 1.11 ENST00000381946.5
ENST00000218548.10
ATPase H+/K+ transporting non-gastric alpha2 subunit
chr19_+_13024917 1.01 ENST00000587260.1
nuclear factor I X
chr14_+_100381974 0.97 ENST00000542471.2
WD repeat domain 25
chr12_+_108129276 0.88 ENST00000547525.6
WSC domain containing 2
chr19_-_14206168 0.88 ENST00000361434.7
ENST00000340736.10
adhesion G protein-coupled receptor L1
chr1_+_85062304 0.83 ENST00000326813.12
ENST00000528899.5
ENST00000294664.11
dynein axonemal intermediate chain 3
chr11_-_2161158 0.83 ENST00000421783.1
ENST00000397262.5
ENST00000381330.5
ENST00000250971.7
ENST00000397270.1
insulin
INS-IGF2 readthrough
chr2_+_218323148 0.82 ENST00000258362.7
PNKD metallo-beta-lactamase domain containing
chr6_-_33069242 0.81 ENST00000437811.1
major histocompatibility complex, class II, DP alpha 1
chr4_+_52051285 0.79 ENST00000295213.9
ENST00000419395.6
spermatogenesis associated 18
chr17_-_80220325 0.78 ENST00000326317.11
ENST00000570427.1
ENST00000570923.1
N-sulfoglucosamine sulfohydrolase
chr2_+_10721649 0.78 ENST00000381661.3
ATPase H+ transporting V1 subunit C2
chr3_-_12158901 0.76 ENST00000287814.5
TIMP metallopeptidase inhibitor 4
chr11_+_1223053 0.75 ENST00000529681.5
mucin 5B, oligomeric mucus/gel-forming
chr6_-_39229465 0.72 ENST00000359534.4
potassium two pore domain channel subfamily K member 5
chr2_+_10721623 0.71 ENST00000272238.9
ATPase H+ transporting V1 subunit C2
chr5_+_76403266 0.70 ENST00000274364.11
IQ motif containing GTPase activating protein 2
chr1_+_3690654 0.68 ENST00000378285.5
ENST00000378280.5
ENST00000378288.8
tumor protein p73
chr17_-_5123102 0.66 ENST00000250076.7
zinc finger protein 232
chr4_+_1011595 0.65 ENST00000510644.6
fibroblast growth factor receptor like 1
chr9_-_122227525 0.65 ENST00000373755.6
ENST00000373754.6
LIM homeobox 6
chr4_-_140427635 0.64 ENST00000325617.10
ENST00000414773.5
calmegin
chr17_+_80220406 0.62 ENST00000573809.5
ENST00000361193.8
ENST00000574967.5
ENST00000576126.5
ENST00000411502.7
ENST00000546047.6
ENST00000572725.5
solute carrier family 26 member 11
chr6_+_33200860 0.61 ENST00000374677.8
solute carrier family 39 member 7
chr17_+_40062810 0.60 ENST00000584985.5
ENST00000264637.8
thyroid hormone receptor alpha
chr12_+_49539022 0.59 ENST00000257981.7
potassium voltage-gated channel subfamily H member 3
chr8_+_67064316 0.59 ENST00000675306.2
ENST00000678017.1
ENST00000262210.11
ENST00000675869.1
ENST00000677009.1
ENST00000676847.1
ENST00000676471.1
ENST00000678542.1
ENST00000677619.1
ENST00000676605.1
ENST00000678553.1
ENST00000674993.1
ENST00000678318.1
ENST00000676573.1
ENST00000676317.1
ENST00000677592.1
ENST00000679226.1
ENST00000675955.1
ENST00000676882.1
ENST00000678616.1
ENST00000678645.1
ENST00000678747.1
centrosome and spindle pole associated protein 1
chr10_+_49610297 0.59 ENST00000374115.5
solute carrier family 18 member A3
chr20_+_36573458 0.57 ENST00000373874.6
TGFB induced factor homeobox 2
chr6_+_33200820 0.56 ENST00000374675.7
solute carrier family 39 member 7
chr6_+_143536811 0.56 ENST00000367584.8
phosphatase and actin regulator 2
chrX_-_54183207 0.56 ENST00000375180.7
ENST00000328235.4
ENST00000477084.1
family with sequence similarity 120C
chrX_-_34657274 0.55 ENST00000275954.4
transmembrane protein 47
chr16_+_67562453 0.55 ENST00000646076.1
CCCTC-binding factor
chr1_+_3652565 0.54 ENST00000354437.8
ENST00000357733.7
ENST00000346387.8
tumor protein p73
chr19_-_3062464 0.54 ENST00000327141.9
TLE family member 5, transcriptional modulator
chr5_+_138352674 0.53 ENST00000314358.10
lysine demethylase 3B
chr4_-_167234579 0.53 ENST00000502330.5
ENST00000357154.7
ENST00000421836.6
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr16_+_67562514 0.53 ENST00000264010.10
ENST00000401394.6
ENST00000646771.1
CCCTC-binding factor
chr4_-_167234426 0.53 ENST00000541354.5
ENST00000509854.5
ENST00000512681.5
ENST00000357545.9
ENST00000510741.5
ENST00000510403.5
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chrX_+_24693879 0.53 ENST00000379068.8
ENST00000677890.1
ENST00000379059.7
DNA polymerase alpha 1, catalytic subunit
chr8_-_101205561 0.52 ENST00000519744.5
ENST00000311212.9
ENST00000521272.5
ENST00000519882.5
zinc finger protein 706
chr9_-_115118198 0.51 ENST00000534839.1
ENST00000535648.5
tenascin C
chr16_+_30985181 0.51 ENST00000262520.10
ENST00000297679.10
ENST00000562932.5
ENST00000574447.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr1_+_3652508 0.50 ENST00000378295.9
ENST00000604074.5
tumor protein p73
chr7_+_23680130 0.50 ENST00000409192.7
ENST00000409653.5
ENST00000409994.3
ENST00000344962.9
family with sequence similarity 221 member A
chr16_+_67807082 0.49 ENST00000567852.5
ENST00000565148.5
ENST00000388833.7
ENST00000561654.5
ENST00000431934.2
translin associated factor X interacting protein 1
chr16_+_67806765 0.49 ENST00000415766.7
ENST00000561639.6
translin associated factor X interacting protein 1
chr19_+_13795434 0.48 ENST00000254323.6
zinc finger SWIM-type containing 4
chr5_+_134371561 0.48 ENST00000265339.7
ENST00000506787.5
ENST00000507277.1
ubiquitin conjugating enzyme E2 B
chr12_-_51026325 0.48 ENST00000547198.5
ENST00000643884.1
solute carrier family 11 member 2
chr17_-_15999689 0.47 ENST00000399277.6
zinc finger SWIM-type containing 7
chr1_-_154956086 0.47 ENST00000368463.8
ENST00000368460.7
ENST00000368465.5
PBX homeobox interacting protein 1
chr17_-_4560564 0.47 ENST00000574584.1
ENST00000381550.8
ENST00000301395.7
gamma-glutamyltransferase 6
chr21_+_32412648 0.46 ENST00000401402.7
ENST00000382699.7
ENST00000300255.7
eva-1 homolog C
chr10_+_44959780 0.43 ENST00000340258.10
ENST00000427758.5
Ras association domain family member 4
chr14_+_93185304 0.42 ENST00000415050.3
transmembrane protein 251
chr5_-_180072086 0.42 ENST00000261947.4
ring finger protein 130
chr17_-_65560296 0.42 ENST00000585045.1
ENST00000611991.1
axin 2
chr12_-_48350771 0.40 ENST00000544117.6
ENST00000548932.5
ENST00000549125.5
ENST00000301042.7
ENST00000547026.6
zinc finger protein 641
chr4_+_105895458 0.40 ENST00000379987.7
nephronectin
chr14_+_91114431 0.39 ENST00000428926.6
ENST00000517362.5
D-glutamate cyclase
chr14_+_91114364 0.39 ENST00000518868.5
D-glutamate cyclase
chr4_-_167234266 0.39 ENST00000511269.5
ENST00000506697.5
ENST00000512042.1
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr17_+_78232006 0.39 ENST00000550981.7
ENST00000591033.2
transmembrane protein 235
chr9_-_137188540 0.39 ENST00000323927.3
anaphase promoting complex subunit 2
chr19_-_12881460 0.39 ENST00000592506.1
deoxyribonuclease 2, lysosomal
chr17_-_5500997 0.38 ENST00000568641.2
novel protein
chr20_+_36573589 0.38 ENST00000373872.9
ENST00000650844.1
TGFB induced factor homeobox 2
chr4_+_73853290 0.38 ENST00000226524.4
platelet factor 4 variant 1
chr12_-_51026345 0.38 ENST00000547732.5
ENST00000644495.1
ENST00000262052.9
ENST00000546488.5
ENST00000550714.5
ENST00000548193.5
ENST00000547579.5
ENST00000546743.5
solute carrier family 11 member 2
chr21_+_41168142 0.37 ENST00000330333.11
beta-secretase 2
chr11_-_118152775 0.37 ENST00000324727.9
sodium voltage-gated channel beta subunit 4
chr4_+_55346349 0.37 ENST00000505210.1
steroid 5 alpha-reductase 3
chr15_-_68229658 0.37 ENST00000565471.6
ENST00000637494.1
ENST00000636314.1
ENST00000637667.1
ENST00000564752.1
ENST00000566347.5
ENST00000249806.11
ENST00000562767.2
CLN6 transmembrane ER protein
novel protein
chr16_-_18376839 0.36 ENST00000427999.6
nuclear pore complex interacting protein family, member A9
chr2_+_229922482 0.36 ENST00000283946.8
ENST00000409992.1
F-box protein 36
chr17_-_10729973 0.35 ENST00000578345.1
ENST00000341871.8
ENST00000455996.6
transmembrane protein 220
chr7_+_149873956 0.35 ENST00000425642.3
ENST00000479613.5
ENST00000606024.5
ENST00000464662.5
ATPase H+ transporting V0 subunit e2
chr12_-_58920465 0.35 ENST00000320743.8
leucine rich repeats and immunoglobulin like domains 3
chr17_-_15999634 0.35 ENST00000472495.5
zinc finger SWIM-type containing 7
chr17_+_20009320 0.34 ENST00000679049.1
ENST00000472876.5
ENST00000583528.6
ENST00000680019.1
ENST00000681593.1
ENST00000395527.8
ENST00000583482.7
ENST00000679255.1
ENST00000681202.1
ENST00000677914.1
sperm antigen with calponin homology and coiled-coil domains 1
chr18_+_13218195 0.33 ENST00000679167.1
low density lipoprotein receptor class A domain containing 4
chr18_+_11752041 0.32 ENST00000423027.8
G protein subunit alpha L
chr22_-_46738205 0.31 ENST00000216264.13
ceramide kinase
chr4_+_105895487 0.31 ENST00000506666.5
ENST00000503451.5
nephronectin
chr12_-_51026141 0.31 ENST00000541174.6
solute carrier family 11 member 2
chr11_-_119340816 0.31 ENST00000528368.3
C1q and TNF related 5
chr11_+_73308237 0.31 ENST00000263674.4
Rho guanine nucleotide exchange factor 17
chr6_-_39115145 0.31 ENST00000229903.5
SAYSVFN motif domain containing 1
chr12_+_51391273 0.31 ENST00000535225.6
ENST00000358657.7
solute carrier family 4 member 8
chr1_-_32336224 0.31 ENST00000329421.8
MARCKS like 1
chr16_+_3012915 0.30 ENST00000445369.3
claudin 9
chr1_+_113929304 0.30 ENST00000426820.7
homeodomain interacting protein kinase 1
chr2_+_237859615 0.30 ENST00000409726.5
ENST00000254661.5
receptor activity modifying protein 1
chr19_-_291132 0.29 ENST00000327790.7
phospholipid phosphatase 2
chr1_-_5992407 0.29 ENST00000378156.9
ENST00000622020.4
nephrocystin 4
chr5_-_9546066 0.29 ENST00000382496.10
ENST00000652226.1
semaphorin 5A
chr11_-_65382632 0.29 ENST00000294187.10
ENST00000398802.6
ENST00000530936.1
solute carrier family 25 member 45
chr17_-_15999589 0.28 ENST00000486655.5
zinc finger SWIM-type containing 7
chr22_+_29306582 0.28 ENST00000616432.4
ENST00000416823.1
ENST00000428622.1
growth arrest specific 2 like 1
chr4_+_499194 0.28 ENST00000453061.7
ENST00000310340.9
ENST00000504346.5
ENST00000503111.5
ENST00000383028.8
ENST00000509768.1
phosphatidylinositol glycan anchor biosynthesis class G
chr1_+_89524871 0.28 ENST00000639264.1
leucine rich repeat containing 8 VRAC subunit B
chr6_-_39314445 0.28 ENST00000453413.2
potassium two pore domain channel subfamily K member 17
chr11_-_62709493 0.28 ENST00000405837.5
ENST00000531524.5
ENST00000524862.6
ENST00000679883.1
BSCL2 lipid droplet biogenesis associated, seipin
chr18_+_11751494 0.28 ENST00000269162.9
G protein subunit alpha L
chr7_-_149773548 0.28 ENST00000302017.4
zinc finger protein 467
chr12_-_7091873 0.28 ENST00000538050.5
ENST00000536053.6
complement C1r
chr19_-_291365 0.28 ENST00000591572.2
ENST00000269812.7
ENST00000633125.1
ENST00000434325.7
phospholipid phosphatase 2
chr10_+_132332273 0.28 ENST00000368613.8
leucine rich repeat containing 27
chr1_+_89524819 0.27 ENST00000439853.6
ENST00000330947.7
ENST00000449440.5
ENST00000640258.1
leucine rich repeat containing 8 VRAC subunit B
chr19_+_48619291 0.27 ENST00000340932.7
ENST00000601712.5
ENST00000600537.5
sphingosine kinase 2
chr4_-_499102 0.26 ENST00000338977.5
ENST00000511833.3
zinc finger protein 721
chr11_-_126062782 0.26 ENST00000531738.6
cell adhesion associated, oncogene regulated
chr19_+_48619528 0.26 ENST00000598088.5
sphingosine kinase 2
chr21_-_33479914 0.26 ENST00000542230.7
transmembrane protein 50B
chr13_-_94712505 0.26 ENST00000376945.4
SRY-box transcription factor 21
chr17_-_17206264 0.26 ENST00000321560.4
phospholipase D family member 6
chr4_-_40629842 0.26 ENST00000295971.12
RNA binding motif protein 47
chr19_+_48619489 0.25 ENST00000245222.9
sphingosine kinase 2
chr3_-_17742498 0.25 ENST00000429383.8
ENST00000446863.5
ENST00000414349.5
ENST00000428355.5
ENST00000425944.5
ENST00000445294.5
ENST00000444471.5
ENST00000415814.6
TBC1 domain family member 5
chr1_+_26111139 0.25 ENST00000619836.4
ENST00000444713.5
PDLIM1 interacting kinase 1 like
chr19_+_1266653 0.25 ENST00000586472.5
ENST00000589266.5
cold inducible RNA binding protein
chr5_+_176810498 0.25 ENST00000509580.2
unc-5 netrin receptor A
chr17_+_79034185 0.25 ENST00000581774.5
C1q and TNF related 1
chrX_+_107628428 0.25 ENST00000643795.2
ENST00000372418.4
ENST00000646815.1
ENST00000372435.10
ENST00000372419.3
ENST00000676092.1
phosphoribosyl pyrophosphate synthetase 1
chr4_+_3074661 0.25 ENST00000355072.11
huntingtin
chr17_-_41034871 0.25 ENST00000344363.7
keratin associated protein 1-3
chr2_+_24491239 0.25 ENST00000348332.8
nuclear receptor coactivator 1
chr5_+_176810552 0.25 ENST00000329542.9
unc-5 netrin receptor A
chr1_-_54406385 0.25 ENST00000610401.5
single stranded DNA binding protein 3
chr14_+_56579782 0.24 ENST00000261556.11
ENST00000538838.5
transmembrane protein 260
chr15_+_65530754 0.24 ENST00000566074.5
3-hydroxyacyl-CoA dehydratase 3
chr19_+_33194308 0.24 ENST00000253193.9
LDL receptor related protein 3
chr9_-_83063159 0.24 ENST00000340717.4
RAS and EF-hand domain containing
chr3_-_64268161 0.24 ENST00000564377.6
prickle planar cell polarity protein 2
chr11_-_76381053 0.24 ENST00000260045.8
THAP domain containing 12
chr2_-_45009401 0.24 ENST00000303077.7
SIX homeobox 2
chr13_+_38687068 0.23 ENST00000280481.9
FRAS1 related extracellular matrix 2
chr1_+_52056284 0.23 ENST00000313334.13
ENST00000472944.6
ENST00000484036.1
basic transcription factor 3 like 4
chr19_-_12881429 0.23 ENST00000222219.8
deoxyribonuclease 2, lysosomal
chr16_-_8868687 0.23 ENST00000618335.4
ENST00000570125.5
calcium regulated heat stable protein 1
chr6_-_41705813 0.23 ENST00000419574.6
ENST00000445214.2
transcription factor EB
chr19_+_49114324 0.23 ENST00000391864.7
lin-7 homolog B, crumbs cell polarity complex component
chr9_-_111484353 0.23 ENST00000338205.9
ENST00000684092.1
Ecm29 proteasome adaptor and scaffold
chr14_+_91114388 0.22 ENST00000519019.5
ENST00000523816.5
ENST00000517518.5
D-glutamate cyclase
chr20_+_44885679 0.22 ENST00000353703.9
ENST00000372839.7
ENST00000428262.1
ENST00000445830.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
chr10_-_98268186 0.22 ENST00000260702.4
lysyl oxidase like 4
chr7_-_100573865 0.22 ENST00000622764.3
Sin3A associated protein 25
chr19_+_49114352 0.22 ENST00000221459.7
ENST00000486217.2
lin-7 homolog B, crumbs cell polarity complex component
chr12_+_55681647 0.22 ENST00000614691.1
methyltransferase like 7B
chr15_+_65530418 0.22 ENST00000562901.5
ENST00000261875.10
ENST00000442729.6
ENST00000565299.5
ENST00000568793.5
3-hydroxyacyl-CoA dehydratase 3
chr5_-_111756245 0.22 ENST00000447165.6
neuronal regeneration related protein
chr1_+_26111798 0.21 ENST00000374269.2
ENST00000374271.8
PDLIM1 interacting kinase 1 like
chr14_-_67533720 0.21 ENST00000554278.6
transmembrane protein 229B
chr16_-_8868994 0.21 ENST00000311052.10
ENST00000565287.5
ENST00000611932.4
calcium regulated heat stable protein 1
chr10_+_69180226 0.21 ENST00000359655.9
ENST00000422378.1
Suv3 like RNA helicase
chr17_-_57988179 0.21 ENST00000581208.2
ENST00000583932.1
vascular endothelial zinc finger 1
chr12_+_55681711 0.21 ENST00000394252.4
methyltransferase like 7B
chr4_+_55346213 0.21 ENST00000679836.1
ENST00000264228.9
ENST00000679707.1
steroid 5 alpha-reductase 3
novel protein, SRD5A3-RP11-177J6.1 readthrough
chr11_-_67508091 0.20 ENST00000531506.1
cyclin dependent kinase 2 associated protein 2
chr8_-_79767843 0.20 ENST00000337919.9
hes related family bHLH transcription factor with YRPW motif 1
chr9_+_128818491 0.20 ENST00000372642.5
endonuclease G
chr11_+_59172116 0.20 ENST00000227451.4
deltex E3 ubiquitin ligase 4
chr7_+_150991005 0.20 ENST00000297494.8
nitric oxide synthase 3
chr3_+_23805941 0.20 ENST00000306627.8
ENST00000346855.7
ubiquitin conjugating enzyme E2 E1
chr19_-_9913819 0.20 ENST00000593091.2
olfactomedin 2
chr10_+_38010617 0.20 ENST00000307441.13
ENST00000374618.7
ENST00000628825.2
ENST00000458705.6
ENST00000432900.7
ENST00000469037.2
zinc finger protein 33A
chr13_-_51804094 0.20 ENST00000280056.6
dehydrogenase/reductase 12
chr18_+_13217676 0.20 ENST00000679177.1
low density lipoprotein receptor class A domain containing 4
chr21_+_45405117 0.20 ENST00000651438.1
collagen type XVIII alpha 1 chain
chr1_+_244835616 0.20 ENST00000366528.3
ENST00000411948.7
cytochrome c oxidase assembly factor COX20
chr17_-_39688016 0.20 ENST00000579146.5
ENST00000300658.9
ENST00000378011.8
ENST00000429199.6
post-GPI attachment to proteins phospholipase 3
chr19_+_50358571 0.20 ENST00000652203.1
nuclear receptor subfamily 1 group H member 2
chr16_-_8868343 0.20 ENST00000562843.5
ENST00000561530.5
ENST00000396593.6
calcium regulated heat stable protein 1
chr8_-_27605271 0.20 ENST00000522098.1
clusterin
chr11_-_74398378 0.19 ENST00000298198.5
phosphoglucomutase 2 like 1
chrX_+_153517672 0.19 ENST00000349466.6
ENST00000370186.5
ENST00000359149.8
ATPase plasma membrane Ca2+ transporting 3
chr9_-_83063135 0.19 ENST00000376447.4
RAS and EF-hand domain containing

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.8 GO:0015670 carbon dioxide transport(GO:0015670)
0.3 3.1 GO:1990253 cellular response to leucine(GO:0071233) cellular response to leucine starvation(GO:1990253)
0.3 0.8 GO:0060266 negative regulation of NAD(P)H oxidase activity(GO:0033861) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.3 0.8 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.2 1.2 GO:0015692 lead ion transport(GO:0015692)
0.2 1.1 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.2 1.7 GO:0035502 metanephric part of ureteric bud development(GO:0035502) negative regulation of interleukin-6 biosynthetic process(GO:0045409) glomerular parietal epithelial cell differentiation(GO:0072139)
0.2 0.8 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.2 0.8 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.2 0.9 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.2 5.1 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.2 0.5 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
0.2 0.5 GO:0060903 regulation of reciprocal meiotic recombination(GO:0010520) positive regulation of meiosis I(GO:0060903)
0.1 0.7 GO:2000721 pilomotor reflex(GO:0097195) positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1 0.4 GO:0061027 umbilical cord morphogenesis(GO:0036304) umbilical cord development(GO:0061027)
0.1 0.5 GO:0006272 leading strand elongation(GO:0006272)
0.1 0.2 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.1 0.6 GO:0016095 polyprenol catabolic process(GO:0016095)
0.1 3.7 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 1.8 GO:0060452 positive regulation of cardiac muscle contraction(GO:0060452)
0.1 1.7 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 5.7 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.1 0.3 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 0.3 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.3 GO:0007309 oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
0.1 0.8 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 1.6 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.8 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.4 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.1 0.2 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.1 0.2 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.1 0.2 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.1 0.6 GO:0015870 acetylcholine transport(GO:0015870)
0.1 0.5 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 5.8 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.1 0.4 GO:2000035 regulation of stem cell division(GO:2000035)
0.1 0.2 GO:0060166 olfactory pit development(GO:0060166)
0.1 0.2 GO:0097168 mesenchymal stem cell proliferation(GO:0097168) positive regulation of chondrocyte proliferation(GO:1902732)
0.1 0.2 GO:0070105 regulation of interleukin-6-mediated signaling pathway(GO:0070103) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 1.1 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.1 1.8 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.1 0.2 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.2 GO:1905006 negative regulation of alkaline phosphatase activity(GO:0010693) negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006)
0.1 0.5 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1 0.2 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.1 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.5 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.6 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.6 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.2 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.4 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.3 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.2 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.3 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.5 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.6 GO:0019532 oxalate transport(GO:0019532)
0.0 0.6 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.1 GO:0071344 diphosphate metabolic process(GO:0071344)
0.0 0.2 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 0.9 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.1 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0 0.2 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.2 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.1 GO:0060309 elastin catabolic process(GO:0060309)
0.0 0.2 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.2 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.2 GO:0060214 endocardium formation(GO:0060214)
0.0 0.2 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.6 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.2 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.6 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0061011 hepatic duct development(GO:0061011) hepatoblast differentiation(GO:0061017)
0.0 0.1 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0 0.3 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.4 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.2 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.1 GO:0099558 maintenance of synapse structure(GO:0099558)
0.0 1.2 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.3 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.1 GO:0070213 negative regulation of protein import into nucleus, translocation(GO:0033159) protein auto-ADP-ribosylation(GO:0070213)
0.0 0.7 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.9 GO:0035584 calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.0 0.2 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.5 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.3 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.2 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.1 GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550)
0.0 0.3 GO:0072553 terminal button organization(GO:0072553)
0.0 0.6 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0038183 bile acid signaling pathway(GO:0038183)
0.0 1.1 GO:0031280 negative regulation of cyclase activity(GO:0031280)
0.0 0.1 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 0.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.4 GO:0086027 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
0.0 0.1 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.5 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.7 GO:0043030 regulation of macrophage activation(GO:0043030)
0.0 0.4 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 0.1 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.4 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.0 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.5 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.2 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.6 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 3.7 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.2 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.0 0.0 GO:0071422 succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.9 GO:0007602 phototransduction(GO:0007602)
0.0 0.2 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.0 0.3 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.6 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.2 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.1 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.3 1.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.3 1.1 GO:0097196 Shu complex(GO:0097196)
0.2 0.7 GO:0070701 mucus layer(GO:0070701)
0.2 1.5 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.2 1.0 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.2 1.2 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.7 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.6 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.5 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 3.8 GO:0009925 basal plasma membrane(GO:0009925)
0.1 7.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 0.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.9 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.3 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.1 GO:0008623 CHRAC(GO:0008623)
0.0 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0044301 climbing fiber(GO:0044301)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 1.1 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.4 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 1.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.4 1.1 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.3 0.8 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.2 1.2 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.2 1.6 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.2 0.9 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.2 3.8 GO:0015250 water channel activity(GO:0015250)
0.2 0.6 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.2 1.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 1.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.6 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.1 0.6 GO:0033765 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 1.7 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 1.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 5.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.8 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 1.0 GO:0045545 syndecan binding(GO:0045545)
0.1 0.3 GO:0001727 lipid kinase activity(GO:0001727)
0.1 0.4 GO:0035939 microsatellite binding(GO:0035939)
0.1 0.6 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 2.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.3 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.2 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 0.3 GO:0004948 calcitonin receptor activity(GO:0004948) calcitonin receptor binding(GO:0031716)
0.1 0.5 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.1 GO:0038181 bile acid receptor activity(GO:0038181)
0.1 0.6 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.8 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.8 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.3 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.7 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.3 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.0 0.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 4.1 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.2 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 1.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 2.7 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.5 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0102344 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.6 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.4 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442) ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.0 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.0 0.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.0 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.4 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.0 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.0 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.0 GO:0046870 cadmium ion binding(GO:0046870)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.0 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 2.1 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 2.3 PID E2F PATHWAY E2F transcription factor network
0.0 1.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 4.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.1 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.6 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.8 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.6 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.1 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 6.0 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.0 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.6 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis