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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for ZKSCAN1

Z-value: 0.85

Motif logo

Transcription factors associated with ZKSCAN1

Gene Symbol Gene ID Gene Info
ENSG00000106261.17 ZKSCAN1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZKSCAN1hg38_v1_chr7_+_100015572_100015583-0.667.8e-05Click!

Activity profile of ZKSCAN1 motif

Sorted Z-values of ZKSCAN1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZKSCAN1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_+_136059151 6.02 ENST00000503087.1
transforming growth factor beta induced
chr22_-_37244417 4.71 ENST00000405484.5
ENST00000441619.5
ENST00000406508.5
Rac family small GTPase 2
chr22_-_37244237 4.41 ENST00000401529.3
ENST00000249071.11
Rac family small GTPase 2
chr11_-_58575846 3.38 ENST00000395074.7
leupaxin
chr5_+_136058849 3.36 ENST00000508076.5
transforming growth factor beta induced
chr14_+_32934383 3.28 ENST00000551634.6
neuronal PAS domain protein 3
chr19_-_18938982 3.01 ENST00000594439.5
ENST00000221222.15
homer scaffold protein 3
chr19_-_18941184 2.68 ENST00000594794.5
ENST00000392351.8
ENST00000596482.5
homer scaffold protein 3
chr12_-_119804298 2.66 ENST00000678652.1
ENST00000678494.1
citron rho-interacting serine/threonine kinase
chr12_-_119804472 2.65 ENST00000678087.1
ENST00000677993.1
citron rho-interacting serine/threonine kinase
chr12_-_24902243 2.65 ENST00000538118.5
branched chain amino acid transaminase 1
chr12_+_4809176 2.32 ENST00000280684.3
potassium voltage-gated channel subfamily A member 6
chr19_-_55149193 2.19 ENST00000587758.5
ENST00000588981.6
ENST00000356783.9
ENST00000291901.12
ENST00000588426.5
ENST00000536926.5
ENST00000588147.5
troponin T1, slow skeletal type
chr1_-_149936324 1.89 ENST00000369140.7
myotubularin related protein 11
chr1_+_209686173 1.88 ENST00000615289.4
ENST00000367028.6
ENST00000261465.5
hydroxysteroid 11-beta dehydrogenase 1
chr3_-_52056552 1.84 ENST00000495880.2
dual specificity phosphatase 7
chr1_+_65147657 1.76 ENST00000546702.5
adenylate kinase 4
chr17_+_17042433 1.73 ENST00000651222.2
myosin phosphatase Rho interacting protein
chr1_+_65147514 1.53 ENST00000545314.5
adenylate kinase 4
chrX_+_47582408 1.47 ENST00000456754.6
ENST00000218388.9
ENST00000377017.5
ENST00000441738.1
TIMP metallopeptidase inhibitor 1
chr1_+_6034677 1.41 ENST00000668559.1
potassium voltage-gated channel subfamily A regulatory beta subunit 2
chr1_+_15756659 1.38 ENST00000375771.5
filamin binding LIM protein 1
chr16_-_19718175 1.38 ENST00000219837.12
lysine rich nucleolar protein 1
chr20_-_57690624 1.34 ENST00000414037.5
prostate transmembrane protein, androgen induced 1
chr3_+_12287962 1.30 ENST00000643197.2
ENST00000644622.2
peroxisome proliferator activated receptor gamma
chr3_+_12287899 1.28 ENST00000643888.2
peroxisome proliferator activated receptor gamma
chr2_+_73892967 1.26 ENST00000409731.7
ENST00000409918.5
ENST00000442912.5
ENST00000345517.8
ENST00000409624.1
actin gamma 2, smooth muscle
chr22_+_32801697 1.26 ENST00000266085.7
TIMP metallopeptidase inhibitor 3
chr3_+_12287859 1.23 ENST00000309576.11
ENST00000397015.7
peroxisome proliferator activated receptor gamma
chr14_+_103385450 1.17 ENST00000416682.6
microtubule affinity regulating kinase 3
chr2_-_65432591 1.16 ENST00000356388.9
sprouty related EVH1 domain containing 2
chr11_+_73264479 1.06 ENST00000393592.7
ENST00000540342.6
ENST00000679753.1
ENST00000542092.5
ENST00000349767.6
pyrimidinergic receptor P2Y6
chr10_-_75099489 1.04 ENST00000472493.6
ENST00000478873.7
ENST00000605915.5
dual specificity phosphatase 13
chr6_+_36676489 0.98 ENST00000448526.6
cyclin dependent kinase inhibitor 1A
chr22_+_20507571 0.95 ENST00000414658.5
ENST00000432052.5
ENST00000292733.11
ENST00000263205.11
ENST00000406969.5
mediator complex subunit 15
chr5_-_128537821 0.95 ENST00000508989.5
fibrillin 2
chr6_+_36676455 0.95 ENST00000615513.4
cyclin dependent kinase inhibitor 1A
chr11_+_33376077 0.93 ENST00000658780.2
KIAA1549 like
chr20_+_44714835 0.93 ENST00000372868.6
cellular communication network factor 5
chr20_+_44714853 0.93 ENST00000372865.4
cellular communication network factor 5
chr5_-_132227472 0.91 ENST00000428369.6
prolyl 4-hydroxylase subunit alpha 2
chr14_+_104724221 0.89 ENST00000330877.7
adenylosuccinate synthase 1
chr2_+_26848093 0.87 ENST00000288699.11
dihydropyrimidinase like 5
chr20_-_775979 0.85 ENST00000676154.1
ENST00000674666.1
ENST00000217254.11
solute carrier family 52 member 3
chr1_+_6034980 0.82 ENST00000378092.6
ENST00000472700.7
potassium voltage-gated channel subfamily A regulatory beta subunit 2
chrX_-_110440218 0.80 ENST00000372057.1
ENST00000372054.3
AMMECR nuclear protein 1
G protein subunit gamma 5 pseudogene 2
chr14_-_106639589 0.78 ENST00000390630.3
immunoglobulin heavy variable 4-61
chr19_-_344786 0.76 ENST00000264819.7
MIER family member 2
chr5_+_110738983 0.74 ENST00000355943.8
ENST00000447245.6
solute carrier family 25 member 46
chr17_-_75154503 0.72 ENST00000409753.8
ENST00000581874.1
Jupiter microtubule associated homolog 1
chr19_+_38647614 0.71 ENST00000252699.7
ENST00000424234.7
ENST00000440400.2
actinin alpha 4
chr7_+_74174323 0.70 ENST00000677570.1
ENST00000265753.13
ENST00000353999.6
ENST00000679266.1
ENST00000679287.1
ENST00000677681.1
eukaryotic translation initiation factor 4H
chr14_+_103385374 0.68 ENST00000678179.1
ENST00000676938.1
ENST00000678619.1
ENST00000440884.7
ENST00000560417.6
ENST00000679330.1
ENST00000556744.2
ENST00000676897.1
ENST00000677560.1
ENST00000561314.6
ENST00000677829.1
ENST00000677133.1
ENST00000676645.1
ENST00000678175.1
ENST00000429436.7
ENST00000677360.1
ENST00000678237.1
ENST00000677347.1
ENST00000677432.1
microtubule affinity regulating kinase 3
chr14_+_103385506 0.66 ENST00000303622.13
microtubule affinity regulating kinase 3
chr6_+_159761991 0.66 ENST00000367048.5
acetyl-CoA acetyltransferase 2
chr11_-_78417788 0.65 ENST00000361507.5
GRB2 associated binding protein 2
chr10_-_124744254 0.65 ENST00000280780.6
family with sequence similarity 53 member B
chr20_+_4171709 0.64 ENST00000379460.6
spermine oxidase
chr8_-_130016622 0.62 ENST00000518283.5
ENST00000519110.5
CYFIP related Rac1 interactor B
chr17_+_19411220 0.62 ENST00000461366.2
ring finger protein 112
chr15_-_34343112 0.61 ENST00000557912.1
ENST00000328848.6
NOP10 ribonucleoprotein
chr19_-_50719761 0.57 ENST00000293441.6
SH3 and multiple ankyrin repeat domains 1
chr20_-_50153637 0.56 ENST00000341698.2
ENST00000371652.9
ENST00000371650.9
PEDS1-UBE2V1 readthrough
plasmanylethanolamine desaturase 1
chr1_+_226223618 0.56 ENST00000542034.5
ENST00000366810.6
Mix paired-like homeobox
chr2_+_26848199 0.56 ENST00000401478.5
dihydropyrimidinase like 5
chr12_+_112978386 0.54 ENST00000342315.8
2'-5'-oligoadenylate synthetase 2
chr16_-_11276473 0.52 ENST00000241808.9
ENST00000435245.2
protamine 2
chr11_-_118264282 0.50 ENST00000278937.7
myelin protein zero like 2
chr12_+_112978562 0.49 ENST00000680122.1
2'-5'-oligoadenylate synthetase 2
chr16_+_32066065 0.49 ENST00000354689.6
immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr8_-_63038788 0.48 ENST00000518113.2
ENST00000260118.7
ENST00000677482.1
gamma-glutamyl hydrolase
chr15_+_75206398 0.46 ENST00000565074.1
chromosome 15 open reading frame 39
chr19_-_15808126 0.45 ENST00000334920.3
olfactory receptor family 10 subfamily H member 1
chr7_-_73328082 0.42 ENST00000333149.7
tripartite motif containing 50
chr21_+_31873010 0.41 ENST00000270112.7
hormonally up-regulated Neu-associated kinase
chr7_+_87934242 0.41 ENST00000413139.2
ENST00000412441.5
ENST00000683525.1
ENST00000398201.8
ENST00000265727.11
ENST00000398209.7
ENST00000684002.1
ADAM metallopeptidase domain 22
chr3_-_64687613 0.40 ENST00000295903.8
ADAM metallopeptidase with thrombospondin type 1 motif 9
chr1_+_16022030 0.40 ENST00000331433.5
chloride voltage-gated channel Ka
chr12_+_8843236 0.39 ENST00000541459.5
alpha-2-macroglobulin like 1
chr1_+_16021871 0.39 ENST00000375692.5
chloride voltage-gated channel Ka
chr17_-_75154534 0.38 ENST00000356033.8
Jupiter microtubule associated homolog 1
chr15_-_73753308 0.37 ENST00000569673.3
inhibitory synaptic factor 1
chr7_+_73328152 0.36 ENST00000252037.5
ENST00000431982.6
FKBP prolyl isomerase family member 6 (inactive)
chr15_-_79923647 0.36 ENST00000485386.1
ENST00000479961.1
ENST00000494999.1
suppressor of tumorigenicity 20
ST20-MTHFS readthrough
chr19_+_35268921 0.35 ENST00000222305.8
ENST00000343550.9
upstream transcription factor 2, c-fos interacting
chr12_+_121888751 0.34 ENST00000261817.6
ENST00000538613.5
ENST00000542602.1
ENST00000541212.6
proteasome 26S subunit, non-ATPase 9
chr1_+_31617683 0.33 ENST00000403528.6
hypocretin receptor 1
chr17_+_77376083 0.33 ENST00000427674.6
septin 9
chr11_+_70203287 0.32 ENST00000301838.5
Fas associated via death domain
chr16_-_788329 0.31 ENST00000563560.1
ENST00000569601.5
ENST00000565809.5
ENST00000007264.7
ENST00000565377.1
ENST00000567114.5
RNA pseudouridine synthase domain containing 1
chr15_-_19988117 0.31 ENST00000558565.2
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr11_-_57649932 0.30 ENST00000524669.5
yippee like 4
chr11_-_57649894 0.28 ENST00000534810.3
ENST00000300022.8
yippee like 4
chr1_-_155301423 0.28 ENST00000342741.6
pyruvate kinase L/R
chr6_+_36954729 0.28 ENST00000373674.4
peptidase inhibitor 16
chr2_+_129979641 0.28 ENST00000410061.4
RAB6C, member RAS oncogene family
chr5_+_156326735 0.28 ENST00000435422.7
sarcoglycan delta
chr7_+_73328177 0.28 ENST00000442793.5
ENST00000413573.6
FKBP prolyl isomerase family member 6 (inactive)
chr5_+_138439020 0.27 ENST00000378339.7
ENST00000254901.9
ENST00000506158.5
receptor accessory protein 2
chr11_-_61430008 0.27 ENST00000394888.8
cleavage and polyadenylation specific factor 7
chr2_-_131364168 0.27 ENST00000623617.3
RAB6D, member RAS oncogene family
chrX_-_131289412 0.26 ENST00000652189.1
ENST00000651556.1
immunoglobulin superfamily member 1
chr10_+_100462969 0.26 ENST00000343737.6
Wnt family member 8B
chr15_-_48810987 0.25 ENST00000399334.7
ENST00000325747.9
centrosomal protein 152
chr10_-_101776104 0.24 ENST00000320185.7
ENST00000344255.8
fibroblast growth factor 8
chrX_+_13655295 0.23 ENST00000380600.1
transcription elongation factor A N-terminal and central domain containing
chrX_-_131289266 0.22 ENST00000370910.5
ENST00000370901.4
ENST00000361420.8
ENST00000370903.8
immunoglobulin superfamily member 1
chr6_-_30672984 0.21 ENST00000415603.1
ENST00000376442.8
DEAH-box helicase 16
chr19_+_35269065 0.21 ENST00000595068.5
ENST00000379134.7
ENST00000594064.5
ENST00000598058.1
upstream transcription factor 2, c-fos interacting
chr1_+_1425854 0.21 ENST00000378821.4
transmembrane protein 88B
chr14_-_75980993 0.21 ENST00000556285.1
transforming growth factor beta 3
chr12_-_102481744 0.21 ENST00000644491.1
insulin like growth factor 1
chr7_+_87934143 0.21 ENST00000398204.8
ADAM metallopeptidase domain 22
chr19_+_38647679 0.20 ENST00000390009.7
ENST00000589528.1
actinin alpha 4
chr19_+_3178756 0.19 ENST00000246115.5
sphingosine-1-phosphate receptor 4
chr19_+_7920313 0.19 ENST00000221573.11
ENST00000595637.1
small nuclear RNA activating complex polypeptide 2
chr4_+_39459069 0.19 ENST00000261434.8
ENST00000340169.7
ENST00000638451.1
ENST00000640349.1
lipoic acid synthetase
chr14_+_63204859 0.18 ENST00000555125.1
ras homolog family member J
chr2_-_182522703 0.17 ENST00000410103.1
phosphodiesterase 1A
chr1_-_201507116 0.17 ENST00000340006.7
ENST00000526256.5
ENST00000526723.5
ENST00000524951.5
cysteine and glycine rich protein 1
chr19_-_38426162 0.17 ENST00000587738.2
ENST00000586305.5
RAS guanyl releasing protein 4
chrX_-_15384402 0.17 ENST00000297904.4
vascular endothelial growth factor D
chr4_+_39459039 0.16 ENST00000509519.5
ENST00000640888.2
ENST00000424936.6
ENST00000381846.2
ENST00000513731.6
lipoic acid synthetase
chr5_+_156327156 0.15 ENST00000337851.9
sarcoglycan delta
chr8_-_30912998 0.15 ENST00000643185.2
testis expressed 15, meiosis and synapsis associated
chr6_+_35297809 0.15 ENST00000316637.7
DEF6 guanine nucleotide exchange factor
chr12_-_111599503 0.15 ENST00000535949.5
ENST00000542287.6
ENST00000616825.4
ENST00000550104.5
ataxin 2
chr1_-_36149464 0.14 ENST00000373166.8
ENST00000373159.1
ENST00000373162.5
ENST00000616074.4
ENST00000616395.4
trafficking protein particle complex 3
chr8_+_22245125 0.14 ENST00000306433.9
ENST00000519237.5
ENST00000397802.8
RNA polymerase III subunit D
chr19_-_38426195 0.14 ENST00000615439.5
ENST00000614135.4
ENST00000622174.4
ENST00000587753.5
ENST00000454404.6
ENST00000617966.4
ENST00000618320.4
ENST00000293062.13
ENST00000433821.6
ENST00000426920.6
RAS guanyl releasing protein 4
chr3_+_184363427 0.13 ENST00000429568.1
RNA polymerase II, I and III subunit H
chr9_-_83538303 0.13 ENST00000304195.8
ENST00000376438.5
FERM domain containing 3
chr22_-_38088915 0.13 ENST00000428572.1
BAR/IMD domain containing adaptor protein 2 like 2
chr10_+_23095556 0.13 ENST00000376510.8
methionine sulfoxide reductase B2
chr3_+_184363387 0.12 ENST00000452961.5
RNA polymerase II, I and III subunit H
chr1_-_36149450 0.11 ENST00000373163.5
trafficking protein particle complex 3
chr11_-_64972070 0.11 ENST00000301896.6
membrane anchored junction protein
chr12_-_10939263 0.10 ENST00000537503.2
taste 2 receptor member 14
chr20_-_49484258 0.10 ENST00000635465.1
potassium voltage-gated channel subfamily B member 1
chr2_+_231037500 0.10 ENST00000373640.5
chromosome 2 open reading frame 72
chr11_-_64972023 0.10 ENST00000530444.5
membrane anchored junction protein
chr17_-_42018488 0.09 ENST00000589773.5
ENST00000674214.1
DnaJ heat shock protein family (Hsp40) member C7
chr10_-_86521737 0.09 ENST00000298767.10
WAPL cohesin release factor
chr20_-_3663399 0.09 ENST00000290417.7
ENST00000319242.8
GDNF family receptor alpha 4
chr2_-_74507664 0.08 ENST00000233630.11
polycomb group ring finger 1
chr6_-_33192454 0.07 ENST00000395194.1
ENST00000341947.7
ENST00000374708.8
collagen type XI alpha 2 chain
chr1_+_16043776 0.07 ENST00000375679.9
chloride voltage-gated channel Kb
chr19_-_50163146 0.06 ENST00000600293.5
IZUMO family member 2
chr4_-_175812746 0.06 ENST00000393658.6
glycoprotein M6A
chrX_+_110002635 0.06 ENST00000372072.7
transmembrane protein 164
chr5_-_135399863 0.06 ENST00000510038.1
ENST00000304332.8
macroH2A.1 histone
chr12_+_13044371 0.05 ENST00000197268.13
family with sequence similarity 234 member B
chr2_+_113173950 0.05 ENST00000245796.11
ENST00000441564.7
pleckstrin and Sec7 domain containing 4
chr10_+_96833019 0.03 ENST00000676381.1
ENST00000675971.1
ENST00000674725.1
ligand dependent nuclear receptor corepressor
chr12_-_133227117 0.03 ENST00000673940.1
anomalous homeobox
chr15_-_78077657 0.03 ENST00000300584.8
ENST00000409931.7
TBC1 domain family member 2B
chr2_+_26848424 0.02 ENST00000431402.5
ENST00000614712.4
ENST00000434719.1
dihydropyrimidinase like 5
chr10_+_96832906 0.02 ENST00000675537.1
ENST00000675117.1
ENST00000356016.7
ENST00000371097.8
ligand dependent nuclear receptor corepressor
chr16_+_56865202 0.02 ENST00000566786.5
ENST00000438926.6
ENST00000563236.6
ENST00000262502.5
solute carrier family 12 member 3
chr6_-_43308797 0.02 ENST00000274990.4
ENST00000372569.8
cysteine rich protein 3
chr19_+_18683656 0.01 ENST00000338797.10
ENST00000321949.13
CREB regulated transcription coactivator 1
chr9_+_130172343 0.01 ENST00000372398.6
neuronal calcium sensor 1
chr3_+_46883337 0.01 ENST00000313049.9
parathyroid hormone 1 receptor
chr19_+_16720004 0.01 ENST00000673803.1
ENST00000549814.5
NACHT and WD repeat domain containing 1
chr5_-_135399211 0.01 ENST00000312469.8
ENST00000423969.6
macroH2A.1 histone

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 9.3 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.5 3.8 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.5 2.6 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.4 3.4 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.3 1.3 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.3 2.2 GO:0070995 NADPH oxidation(GO:0070995)
0.3 3.3 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.3 1.3 GO:0090131 mesenchyme migration(GO:0090131)
0.2 0.7 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.2 2.2 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.2 1.9 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.2 2.5 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.2 5.7 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.2 0.6 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 1.5 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.1 0.9 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417) positive regulation of pinocytosis(GO:0048549)
0.1 0.6 GO:0046208 spermine catabolic process(GO:0046208)
0.1 0.5 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 1.0 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.3 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.3 GO:0009106 lipoate metabolic process(GO:0009106)
0.1 0.6 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.1 0.3 GO:0035698 CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.1 1.4 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.8 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.6 GO:0019086 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086)
0.1 1.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 5.3 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 1.9 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.1 0.6 GO:0050893 sensory processing(GO:0050893)
0.1 0.2 GO:0090134 corticotropin hormone secreting cell differentiation(GO:0060128) mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.1 1.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.2 GO:0003032 detection of oxygen(GO:0003032)
0.1 3.0 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.7 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 0.3 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 9.1 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 0.3 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 0.2 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.9 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.6 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.3 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.6 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.1 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.0 0.4 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.0 0.3 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.3 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 1.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.2 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.6 GO:0045687 positive regulation of glial cell differentiation(GO:0045687)
0.0 0.6 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.8 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.5 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.4 GO:0035411 catenin import into nucleus(GO:0035411)
0.0 0.5 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.3 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:1990031 pinceau fiber(GO:1990031)
0.4 1.9 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 2.2 GO:0005861 troponin complex(GO:0005861)
0.1 0.6 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1 9.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 12.1 GO:0005604 basement membrane(GO:0005604)
0.1 5.7 GO:0045178 basal part of cell(GO:0045178)
0.1 3.4 GO:0002102 podosome(GO:0002102)
0.0 0.4 GO:0016011 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0 1.3 GO:0032982 myosin filament(GO:0032982)
0.0 1.0 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 5.3 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.9 GO:0031143 pseudopodium(GO:0031143)
0.0 1.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.1 GO:0005592 collagen type XI trimer(GO:0005592)
0.0 0.5 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 1.4 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 2.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.7 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.3 GO:0005849 mRNA cleavage factor complex(GO:0005849)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.3 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.6 1.9 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.5 2.6 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.4 1.9 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.3 3.8 GO:0050692 DBD domain binding(GO:0050692)
0.3 5.7 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.3 1.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 1.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.2 0.7 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.2 0.6 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.2 2.2 GO:0031014 troponin T binding(GO:0031014)
0.2 0.9 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 0.3 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.1 2.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.0 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.8 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.3 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.1 9.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.6 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.6 GO:0071532 GKAP/Homer scaffold activity(GO:0030160) ankyrin repeat binding(GO:0071532)
0.1 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 2.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.5 GO:0046870 cadmium ion binding(GO:0046870)
0.1 5.3 GO:0097110 scaffold protein binding(GO:0097110)
0.1 0.3 GO:0035877 death effector domain binding(GO:0035877)
0.1 0.7 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 0.5 GO:0034711 inhibin binding(GO:0034711)
0.0 1.4 GO:0031005 filamin binding(GO:0031005)
0.0 2.2 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 8.9 GO:0019887 protein kinase regulator activity(GO:0019887)
0.0 1.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.4 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.9 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 1.3 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 1.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.5 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.9 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 9.0 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 1.9 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 5.3 PID RHOA PATHWAY RhoA signaling pathway
0.1 3.8 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 2.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 2.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.1 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 9.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 1.8 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 2.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.9 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 4.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.9 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 1.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 4.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 3.4 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.9 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis