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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for ZNF232

Z-value: 0.30

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Transcription factors associated with ZNF232

Gene Symbol Gene ID Gene Info
ZNF232
ENSG00000167840.13 ZNF232

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF232hg38_v1_chr17_-_5111836_5111845,
hg38_v1_chr17_-_5123102_5123128		-0.451.2e-02Click!

Activity profile of ZNF232 motif

Sorted Z-values of ZNF232 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF232

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_-_31414694 1.23 ENST00000379416.4
XDH
xanthine dehydrogenase
chr2_-_112764600 0.76 ENST00000302450.11
CKAP2L
cytoskeleton associated protein 2 like
chr17_+_41819201 0.72 ENST00000455106.1
FKBP10
FKBP prolyl isomerase 10
chrX_+_101550537 0.63 ENST00000372829.8
ARMCX1
armadillo repeat containing X-linked 1
chr1_-_79006773 0.50 ENST00000671209.1
ADGRL4
adhesion G protein-coupled receptor L4
chr16_+_11345429 0.49 ENST00000576027.1
ENST00000312499.6
ENST00000648619.1
RMI2
RecQ mediated genome instability 2
chr9_+_5231413 0.37 ENST00000239316.4
INSL4
insulin like 4
chr4_+_95840084 0.36 ENST00000295266.6
PDHA2
pyruvate dehydrogenase E1 subunit alpha 2
chr1_-_79006680 0.34 ENST00000370742.4
ENST00000656841.1
ADGRL4
adhesion G protein-coupled receptor L4
chr11_+_35189964 0.31 ENST00000524922.1
CD44
CD44 molecule (Indian blood group)
chr3_-_185498964 0.30 ENST00000296254.3
TMEM41A
transmembrane protein 41A
chr11_-_18106019 0.28 ENST00000532452.5
ENST00000530180.1
ENST00000524803.6
ENST00000300013.8
ENST00000529318.5
SAAL1
serum amyloid A like 1
chr22_-_29838227 0.27 ENST00000307790.8
ENST00000397771.6
ENST00000542393.5
ASCC2
activating signal cointegrator 1 complex subunit 2
chr9_+_114323098 0.25 ENST00000259396.9
ORM1
orosomucoid 1
chr12_+_75481204 0.24 ENST00000550491.1
GLIPR1
GLI pathogenesis related 1
chr14_-_106675544 0.24 ENST00000390632.2
IGHV3-66
immunoglobulin heavy variable 3-66
chrX_+_50067576 0.23 ENST00000376108.7
CLCN5
chloride voltage-gated channel 5
chr17_+_18744026 0.21 ENST00000308799.8
ENST00000395665.9
ENST00000301938.4
FBXW10
F-box and WD repeat domain containing 10
chr4_-_87529460 0.21 ENST00000418378.5
SPARCL1
SPARC like 1
chr18_+_58149314 0.18 ENST00000435432.6
ENST00000357895.9
ENST00000586263.5
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr3_-_123585013 0.18 ENST00000383657.10
HACD2
3-hydroxyacyl-CoA dehydratase 2
chr16_+_30650728 0.18 ENST00000568754.5
PRR14
proline rich 14
chr14_-_106360320 0.17 ENST00000390615.2
IGHV3-33
immunoglobulin heavy variable 3-33
chr2_+_74198605 0.17 ENST00000409804.5
ENST00000678340.1
ENST00000679055.1
ENST00000394053.7
ENST00000409601.1
MTHFD2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr3_-_185499022 0.17 ENST00000421852.6
TMEM41A
transmembrane protein 41A
chr9_-_41908681 0.16 ENST00000476961.5
CNTNAP3B
contactin associated protein family member 3B
chr15_-_60478929 0.15 ENST00000558512.5
ENST00000561114.5
ICE2
interactor of little elongation complex ELL subunit 2
chr6_+_109095110 0.15 ENST00000521277.5
ENST00000407272.5
ENST00000519286.5
CEP57L1
centrosomal protein 57 like 1
chr2_-_224947030 0.15 ENST00000409592.7
DOCK10
dedicator of cytokinesis 10
chr1_-_35641498 0.15 ENST00000373237.4
PSMB2
proteasome 20S subunit beta 2
chrX_-_131289412 0.15 ENST00000652189.1
ENST00000651556.1
IGSF1
immunoglobulin superfamily member 1
chr2_-_166149204 0.15 ENST00000635750.1
SCN1A
sodium voltage-gated channel alpha subunit 1
chr21_+_37420299 0.14 ENST00000455097.6
ENST00000643854.1
ENST00000645424.1
ENST00000642309.1
ENST00000645774.1
ENST00000398956.2
DYRK1A
dual specificity tyrosine phosphorylation regulated kinase 1A
chr2_-_166149120 0.14 ENST00000641575.1
ENST00000641603.1
SCN1A
sodium voltage-gated channel alpha subunit 1
chr10_+_49609095 0.14 ENST00000339797.5
CHAT
choline O-acetyltransferase
chr16_+_50025217 0.13 ENST00000427478.7
CNEP1R1
CTD nuclear envelope phosphatase 1 regulatory subunit 1
chr3_+_8501807 0.13 ENST00000426878.2
ENST00000397386.7
ENST00000415597.5
ENST00000157600.8
LMCD1
LIM and cysteine rich domains 1
chr1_-_193105373 0.13 ENST00000367439.8
GLRX2
glutaredoxin 2
chr16_+_30650932 0.13 ENST00000300835.9
PRR14
proline rich 14
chr15_-_34343112 0.13 ENST00000557912.1
ENST00000328848.6
NOP10
NOP10 ribonucleoprotein
chr5_+_147878703 0.12 ENST00000296694.5
SCGB3A2
secretoglobin family 3A member 2
chr16_+_30651039 0.12 ENST00000542965.2
PRR14
proline rich 14
chr3_+_184300564 0.12 ENST00000435761.5
ENST00000439383.5
PSMD2
proteasome 26S subunit, non-ATPase 2
chr19_+_17933001 0.11 ENST00000445755.7
CCDC124
coiled-coil domain containing 124
chr15_-_79090760 0.11 ENST00000419573.7
ENST00000558480.7
RASGRF1
Ras protein specific guanine nucleotide releasing factor 1
chr6_+_124983356 0.10 ENST00000519799.5
ENST00000368414.6
ENST00000359704.2
RNF217
ring finger protein 217
chr5_+_150357629 0.10 ENST00000650162.1
ENST00000377797.7
ENST00000445265.6
ENST00000323668.11
ENST00000643257.2
ENST00000646961.1
ENST00000513538.2
ENST00000439160.6
ENST00000394269.7
ENST00000427724.7
ENST00000504761.6
ENST00000513346.5
ENST00000515516.1
TCOF1
treacle ribosome biogenesis factor 1
chr5_-_180649579 0.09 ENST00000261937.11
ENST00000502649.5
FLT4
fms related receptor tyrosine kinase 4
chr19_-_49877279 0.09 ENST00000391832.7
ENST00000344175.10
AKT1S1
AKT1 substrate 1
chr1_+_202203721 0.09 ENST00000255432.11
LGR6
leucine rich repeat containing G protein-coupled receptor 6
chr10_-_114144599 0.06 ENST00000428953.1
CCDC186
coiled-coil domain containing 186
chr4_+_39406917 0.06 ENST00000257408.5
KLB
klotho beta
chr1_+_182450132 0.06 ENST00000294854.13
RGSL1
regulator of G protein signaling like 1
chr12_-_9733292 0.05 ENST00000621400.4
ENST00000327839.3
CLECL1
C-type lectin like 1
chrX_-_101293057 0.05 ENST00000372907.7
TAF7L
TATA-box binding protein associated factor 7 like
chr11_+_18172837 0.05 ENST00000314254.3
MRGPRX4
MAS related GPR family member X4
chr14_+_22547495 0.05 ENST00000611116.2
TRAC
T cell receptor alpha constant
chr20_+_4148779 0.04 ENST00000621355.4
ENST00000339123.10
ENST00000278795.7
ENST00000305958.9
ENST00000346595.6
SMOX
spermine oxidase
chr5_+_95646730 0.04 ENST00000511684.5
ENST00000380005.9
RFESD
Rieske Fe-S domain containing
chr5_+_95646854 0.04 ENST00000311364.8
ENST00000458310.1
RFESD
Rieske Fe-S domain containing
chr18_+_63970029 0.04 ENST00000353706.6
ENST00000542677.5
ENST00000397985.7
ENST00000636430.1
ENST00000397988.7
ENST00000448851.5
SERPINB8
serpin family B member 8
chr3_+_127915226 0.04 ENST00000405109.5
KBTBD12
kelch repeat and BTB domain containing 12
chr7_-_1569955 0.04 ENST00000288607.3
ENST00000404674.7
PSMG3
proteasome assembly chaperone 3
chr2_-_74392025 0.04 ENST00000440727.1
ENST00000409240.5
DCTN1
dynactin subunit 1
chr19_-_15125751 0.03 ENST00000263383.8
ILVBL
ilvB acetolactate synthase like
chr1_+_248445512 0.03 ENST00000642130.1
ENST00000641925.2
OR2T2
olfactory receptor family 2 subfamily T member 2
chr1_+_203795614 0.03 ENST00000367210.3
ENST00000432282.5
ENST00000453771.5
ENST00000367214.5
ENST00000639812.1
ENST00000367212.7
ENST00000332127.8
ENST00000550078.2
ZC3H11A
ZBED6
zinc finger CCCH-type containing 11A
zinc finger BED-type containing 6
chr1_-_160579439 0.02 ENST00000368054.8
ENST00000368048.7
ENST00000311224.8
ENST00000368051.3
ENST00000534968.5
CD84
CD84 molecule
chr2_+_233917371 0.01 ENST00000324695.9
ENST00000433712.6
TRPM8
transient receptor potential cation channel subfamily M member 8
chr5_+_31532277 0.01 ENST00000507818.6
ENST00000325366.14
C5orf22
chromosome 5 open reading frame 22
chr14_-_24242600 0.01 ENST00000646753.1
ENST00000558566.1
ENST00000267415.12
ENST00000559019.1
ENST00000399423.8
ENST00000626689.2
TINF2
TERF1 interacting nuclear factor 2
chr7_-_100479142 0.01 ENST00000300181.7
ENST00000393991.5
TSC22D4
TSC22 domain family member 4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.3 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:1990523 bone regeneration(GO:1990523)
0.0 0.3 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.4 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.3 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.5 GO:0000732 strand displacement(GO:0000732)
0.0 0.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0042262 DNA protection(GO:0042262)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.4 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.1 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.1 0.4 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 0.2 GO:0080023 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
0.0 0.2 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.1 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.0 0.7 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0030613 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.0 GO:0052901 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation