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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for ZNF274

Z-value: 0.26

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Transcription factors associated with ZNF274

Gene Symbol Gene ID Gene Info
ZNF274
ENSG00000171606.18 ZNF274

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF274hg38_v1_chr19_+_58183375_58183494-0.009.8e-01Click!

Activity profile of ZNF274 motif

Sorted Z-values of ZNF274 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF274

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr16_-_4752565 0.84 ENST00000588099.1
ENST00000588942.1
ENSG00000266994.1
ZNF500
novel transcript
zinc finger protein 500
chr1_+_44739825 0.68 ENST00000372224.9
KIF2C
kinesin family member 2C
chr19_+_39655907 0.41 ENST00000392051.4
LGALS16
galectin 16
chr19_-_42877988 0.26 ENST00000597058.1
PSG1
pregnancy specific beta-1-glycoprotein 1
chr12_-_54259531 0.25 ENST00000550411.5
ENST00000439541.6
CBX5
chromobox 5
chr16_+_29807536 0.25 ENST00000567444.5
MAZ
MYC associated zinc finger protein
chr22_+_38957522 0.23 ENST00000618553.1
ENST00000249116.7
APOBEC3A
apolipoprotein B mRNA editing enzyme catalytic subunit 3A
chr6_+_31586124 0.21 ENST00000418507.6
ENST00000376096.5
ENST00000376099.5
ENST00000376110.7
LST1
leukocyte specific transcript 1
chr3_+_102435015 0.20 ENST00000306176.5
ENST00000466937.2
ZPLD1
zona pellucida like domain containing 1
chr6_+_31586269 0.20 ENST00000438075.7
LST1
leukocyte specific transcript 1
chr19_+_6135635 0.16 ENST00000588304.5
ENST00000588722.5
ENST00000588485.6
ENST00000591403.5
ENST00000586696.5
ENST00000681525.1
ENST00000589401.5
ACSBG2
acyl-CoA synthetase bubblegum family member 2
chr3_-_139044892 0.16 ENST00000413199.1
PRR23C
proline rich 23C
chr6_+_30720335 0.15 ENST00000327892.13
TUBB
tubulin beta class I
chr8_-_4994972 0.15 ENST00000520002.5
ENST00000602557.5
CSMD1
CUB and Sushi multiple domains 1
chr17_+_35587239 0.15 ENST00000621914.4
ENST00000621668.4
ENST00000616681.4
ENST00000612035.4
ENST00000610402.5
ENST00000614600.4
ENST00000590432.5
ENST00000612116.5
AP2B1
adaptor related protein complex 2 subunit beta 1
chr11_-_10568571 0.15 ENST00000529598.1
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr14_-_23578756 0.14 ENST00000397118.7
ENST00000356300.9
JPH4
junctophilin 4
chr6_-_83431038 0.14 ENST00000369705.4
ME1
malic enzyme 1
chr8_-_4994696 0.13 ENST00000400186.7
ENST00000602723.5
CSMD1
CUB and Sushi multiple domains 1
chr14_+_21941122 0.12 ENST00000390441.2
TRAV9-2
T cell receptor alpha variable 9-2
chr6_-_127459364 0.12 ENST00000487331.2
ENST00000483725.8
KIAA0408
KIAA0408
chr2_-_88992903 0.12 ENST00000495489.1
IGKV1-8
immunoglobulin kappa variable 1-8
chr1_+_156282917 0.11 ENST00000295694.9
ENST00000357501.6
TMEM79
transmembrane protein 79
chr19_+_39704461 0.11 ENST00000360675.7
ENST00000392052.8
ENST00000601802.1
LGALS14
galectin 14
chr16_+_29807775 0.10 ENST00000568411.5
ENST00000563012.1
ENST00000562557.5
MAZ
MYC associated zinc finger protein
chr18_+_9885964 0.10 ENST00000357775.6
ENST00000306084.6
TXNDC2
thioredoxin domain containing 2
chr3_+_128153422 0.09 ENST00000254730.11
ENST00000483457.1
EEFSEC
eukaryotic elongation factor, selenocysteine-tRNA specific
chr8_-_4994904 0.09 ENST00000635120.2
CSMD1
CUB and Sushi multiple domains 1
chr3_+_50246888 0.08 ENST00000451956.1
GNAI2
G protein subunit alpha i2
chr5_+_32531786 0.08 ENST00000512913.5
SUB1
SUB1 regulator of transcription
chr1_+_42463221 0.08 ENST00000654683.1
ENST00000667205.1
ENST00000655164.1
ENST00000657597.1
ENST00000667947.1
ENST00000668663.1
ENST00000660083.1
ENST00000655845.1
ENST00000671281.1
ENST00000664805.1
ENST00000654604.1
ENST00000655447.1
ENST00000661864.1
ENST00000665176.1
ENST00000670982.1
ENST00000668036.1
CCDC30
coiled-coil domain containing 30
chr19_+_41443130 0.06 ENST00000378187.3
ERICH4
glutamate rich 4
chrX_+_120604199 0.06 ENST00000371315.3
MCTS1
MCTS1 re-initiation and release factor
chrX_+_120604084 0.06 ENST00000371317.10
MCTS1
MCTS1 re-initiation and release factor
chr11_+_55885920 0.06 ENST00000244891.3
TRIM51
tripartite motif-containing 51
chr10_+_69278492 0.05 ENST00000643399.2
HK1
hexokinase 1
chr18_+_9885726 0.05 ENST00000611534.1
ENST00000536353.2
ENST00000584255.1
TXNDC2
thioredoxin domain containing 2
chr17_-_3557798 0.05 ENST00000301365.8
ENST00000572519.1
ENST00000576742.6
TRPV3
transient receptor potential cation channel subfamily V member 3
chr16_+_29808125 0.04 ENST00000568282.1
MAZ
MYC associated zinc finger protein
chr20_-_59042748 0.04 ENST00000355937.9
ENST00000371033.9
PRELID3B
PRELI domain containing 3B
chr16_+_29808051 0.04 ENST00000568544.5
ENST00000569978.1
MAZ
MYC associated zinc finger protein
chr11_-_10568650 0.03 ENST00000256178.8
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr9_-_33473884 0.03 ENST00000297990.9
ENST00000353159.6
ENST00000379471.3
NOL6
nucleolar protein 6
chr15_+_88621290 0.02 ENST00000332810.4
ENST00000559528.1
AEN
apoptosis enhancing nuclease
chrX_-_142205260 0.02 ENST00000247452.4
MAGEC2
MAGE family member C2
chr19_+_15793951 0.01 ENST00000308940.8
OR10H5
olfactory receptor family 10 subfamily H member 5
chr7_+_30752127 0.01 ENST00000013222.5
ENST00000409539.1
INMT
indolethylamine N-methyltransferase
chr8_-_19682576 0.01 ENST00000332246.10
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr2_+_178112416 0.01 ENST00000286070.10
ENST00000616198.4
RBM45
RNA binding motif protein 45
chr3_-_69080350 0.01 ENST00000630585.1
ENST00000361055.9
ENST00000415609.6
ENST00000349511.8
UBA3
ubiquitin like modifier activating enzyme 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.2 GO:0070383 DNA cytosine deamination(GO:0070383)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.5 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 0.1 GO:0042335 cuticle development(GO:0042335)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741) regulation of NADP metabolic process(GO:1902031)
0.0 0.1 GO:0006662 glycerol ether metabolic process(GO:0006662)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0030314 junctional membrane complex(GO:0030314)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 0.4 GO:0030395 lactose binding(GO:0030395)
0.0 0.2 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.0 0.1 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins