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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for ZNF423

Z-value: 0.80

Motif logo

Transcription factors associated with ZNF423

Gene Symbol Gene ID Gene Info
ENSG00000102935.12 ZNF423

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF423hg38_v1_chr16_-_49664225_496642980.431.7e-02Click!

Activity profile of ZNF423 motif

Sorted Z-values of ZNF423 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF423

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_+_151020438 2.92 ENST00000622181.4
ENST00000614343.4
ENST00000388825.9
ENST00000521650.5
ENST00000517973.1
glutathione peroxidase 3
chr19_-_41353044 2.32 ENST00000600196.2
ENST00000677934.1
transforming growth factor beta 1
chr19_-_11578937 2.29 ENST00000592659.1
ENST00000592828.6
ENST00000218758.9
ENST00000412435.6
acid phosphatase 5, tartrate resistant
chr1_-_204151884 2.28 ENST00000367201.7
ethanolamine kinase 2
chr1_-_204152010 2.09 ENST00000367202.9
ethanolamine kinase 2
chr8_+_22165140 2.04 ENST00000397814.7
ENST00000354870.5
bone morphogenetic protein 1
chr8_+_22165358 1.99 ENST00000306349.13
ENST00000306385.10
bone morphogenetic protein 1
chr10_-_119536533 1.96 ENST00000392865.5
regulator of G protein signaling 10
chr11_-_61295289 1.77 ENST00000335613.10
von Willebrand factor C and EGF domains
chr5_+_136049513 1.71 ENST00000514554.5
transforming growth factor beta induced
chrX_-_51496572 1.55 ENST00000375992.4
nudix hydrolase 11
chr9_+_109780292 1.46 ENST00000374530.7
PALM2 and AKAP2 fusion
chr11_+_61828280 1.44 ENST00000521849.5
ENST00000278840.9
fatty acid desaturase 2
chr17_+_6444441 1.43 ENST00000250056.12
ENST00000571373.5
ENST00000570337.6
ENST00000572595.6
ENST00000572447.6
ENST00000576056.5
PICALM interacting mitotic regulator
chr16_+_71358713 1.37 ENST00000349553.9
ENST00000302628.9
ENST00000562305.5
calbindin 2
chr11_+_60924452 1.32 ENST00000453848.7
ENST00000544065.5
ENST00000005286.8
transmembrane protein 132A
chr11_-_61891381 1.31 ENST00000525588.5
fatty acid desaturase 3
chr11_-_107858777 1.28 ENST00000525815.6
solute carrier family 35 member F2
chr22_-_37427433 1.27 ENST00000452946.1
ENST00000402918.7
extracellular leucine rich repeat and fibronectin type III domain containing 2
extracellular leucine rich repeat and fibronectin type III domain containing 2
chr9_-_128724088 1.26 ENST00000406904.2
ENST00000452105.5
ENST00000372667.9
ENST00000372663.9
zinc finger DHHC-type palmitoyltransferase 12
chr2_+_27496830 1.21 ENST00000264717.7
glucokinase regulator
chr17_+_7438267 1.16 ENST00000575235.5
fibroblast growth factor 11
chr19_+_35533436 1.13 ENST00000222286.9
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr5_+_53480619 1.12 ENST00000396947.7
ENST00000256759.8
follistatin
chr11_-_61891534 1.06 ENST00000278829.7
fatty acid desaturase 3
chr10_-_75099489 1.04 ENST00000472493.6
ENST00000478873.7
ENST00000605915.5
dual specificity phosphatase 13
chrX_+_49171889 1.03 ENST00000376327.6
proteolipid protein 2
chrX_-_107775951 1.02 ENST00000315660.8
ENST00000372384.6
ENST00000502650.1
ENST00000506724.1
TSC22 domain family member 3
chr3_-_48556785 1.02 ENST00000232375.8
ENST00000383734.6
ENST00000416568.5
ENST00000412035.5
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr1_-_155207886 1.01 ENST00000368378.7
ENST00000541990.5
ENST00000457183.6
ENST00000541576.5
thrombospondin 3
chr10_+_133527355 1.01 ENST00000252945.8
ENST00000421586.5
ENST00000418356.1
cytochrome P450 family 2 subfamily E member 1
chr7_-_23014074 1.00 ENST00000409763.1
ENST00000679826.1
ENST00000409923.5
ENST00000681766.1
family with sequence similarity 126 member A
chr1_+_26993684 0.96 ENST00000522111.3
TMF1 regulated nuclear protein 1
chrX_-_107775740 0.95 ENST00000372383.9
TSC22 domain family member 3
chr1_-_6180265 0.95 ENST00000262450.8
chromodomain helicase DNA binding protein 5
chr8_+_22565236 0.92 ENST00000523900.5
sorbin and SH3 domain containing 3
chr7_-_23014099 0.91 ENST00000432176.7
ENST00000440481.6
family with sequence similarity 126 member A
chr19_-_15200902 0.91 ENST00000601011.1
ENST00000263388.7
notch receptor 3
chr9_-_37904085 0.89 ENST00000377716.6
ENST00000242275.7
solute carrier family 25 member 51
chr12_-_54385727 0.89 ENST00000551109.5
ENST00000546970.5
zinc finger protein 385A
chr19_+_45079195 0.79 ENST00000591607.1
ENST00000591747.5
ENST00000270257.9
ENST00000391951.2
ENST00000587566.5
gem nuclear organelle associated protein 7
microtubule affinity regulating kinase 4
chr5_+_169583636 0.79 ENST00000506574.5
ENST00000515224.5
ENST00000629457.2
ENST00000508247.5
ENST00000265295.9
ENST00000513941.5
spindle apparatus coiled-coil protein 1
chr3_+_6861107 0.72 ENST00000357716.9
ENST00000486284.5
ENST00000389336.8
glutamate metabotropic receptor 7
chr9_+_113876282 0.72 ENST00000374126.9
ENST00000615615.4
ENST00000288466.11
zinc finger protein 618
chr9_+_109780312 0.70 ENST00000483909.5
ENST00000413420.5
ENST00000302798.7
PALM2 and AKAP2 fusion
chr1_+_155308930 0.68 ENST00000465559.5
ENST00000612683.1
farnesyl diphosphate synthase
chr3_-_196082078 0.67 ENST00000360110.9
ENST00000392396.7
ENST00000420415.5
transferrin receptor
chr19_+_45467988 0.62 ENST00000615753.4
ENST00000585836.5
ENST00000417353.6
ENST00000591858.5
ENST00000443841.6
ENST00000590335.1
ENST00000353609.8
FosB proto-oncogene, AP-1 transcription factor subunit
chr2_+_62705644 0.61 ENST00000427809.5
ENST00000405482.5
ENST00000431489.6
EH domain binding protein 1
chr18_-_5543988 0.61 ENST00000341928.7
erythrocyte membrane protein band 4.1 like 3
chr19_+_45251363 0.59 ENST00000620044.4
microtubule affinity regulating kinase 4
chr1_+_155308748 0.57 ENST00000611010.4
ENST00000447866.5
ENST00000368356.9
ENST00000467076.5
ENST00000491013.5
ENST00000356657.10
farnesyl diphosphate synthase
chrX_+_49171918 0.57 ENST00000376322.7
proteolipid protein 2
chr16_+_3046552 0.57 ENST00000336577.9
matrix metallopeptidase 25
chr15_+_41231219 0.56 ENST00000334660.10
ENST00000560397.5
calcineurin like EF-hand protein 1
chr16_+_27313879 0.55 ENST00000562142.5
ENST00000561742.5
ENST00000543915.6
ENST00000395762.7
ENST00000563002.5
interleukin 4 receptor
chr9_+_132162045 0.54 ENST00000393229.4
netrin G2
chr8_+_30384511 0.54 ENST00000339877.8
ENST00000320203.8
ENST00000287771.9
ENST00000397323.9
RNA binding protein, mRNA processing factor
chr19_+_45251249 0.54 ENST00000262891.9
ENST00000300843.8
microtubule affinity regulating kinase 4
chr8_+_22565655 0.53 ENST00000523965.5
sorbin and SH3 domain containing 3
chr10_+_123154364 0.51 ENST00000368859.6
ENST00000368865.9
BUB3 mitotic checkpoint protein
chr6_+_33621313 0.50 ENST00000605930.3
inositol 1,4,5-trisphosphate receptor type 3
chr19_-_42242526 0.49 ENST00000222330.8
ENST00000676537.1
glycogen synthase kinase 3 alpha
chr16_+_2964216 0.47 ENST00000572045.5
ENST00000571007.5
ENST00000575885.5
ENST00000303746.10
ENST00000319500.10
kringle containing transmembrane protein 2
chr6_+_11093753 0.46 ENST00000416247.4
small integral membrane protein 13
chr6_+_142147162 0.45 ENST00000452973.6
ENST00000620996.4
ENST00000367621.1
ENST00000367630.9
vesicle trafficking 1
chr19_-_46714269 0.45 ENST00000600194.5
protein kinase D2
chr4_-_20984011 0.45 ENST00000382149.9
potassium voltage-gated channel interacting protein 4
chr11_-_67353503 0.44 ENST00000539074.1
ENST00000530584.5
ENST00000531239.2
ENST00000312419.8
ENST00000529704.5
DNA polymerase delta 4, accessory subunit
chr1_+_1512137 0.44 ENST00000378756.8
ENST00000378755.9
ATPase family AAA domain containing 3A
chr12_-_49707220 0.43 ENST00000550488.5
formin like 3
chr20_-_31475125 0.43 ENST00000317676.3
defensin beta 124
chr1_-_101996919 0.42 ENST00000370103.9
olfactomedin 3
chr7_-_44225893 0.40 ENST00000425809.5
calcium/calmodulin dependent protein kinase II beta
chrX_+_106920393 0.40 ENST00000336803.2
claudin 2
chr22_+_35257452 0.39 ENST00000420166.5
ENST00000216106.6
ENST00000455359.5
HMG-box containing 4
chr8_-_42377227 0.38 ENST00000220812.3
dickkopf WNT signaling pathway inhibitor 4
chr17_-_29180359 0.37 ENST00000531253.5
ENST00000628822.2
myosin XVIIIA
chr19_-_11481044 0.36 ENST00000359227.8
ELAV like RNA binding protein 3
chr20_+_44401269 0.36 ENST00000443598.6
ENST00000415691.2
hepatocyte nuclear factor 4 alpha
chr19_-_56671746 0.35 ENST00000537055.4
ENST00000601659.1
zinc finger protein 835
chr20_+_44401397 0.35 ENST00000682427.1
ENST00000681977.1
ENST00000684136.1
ENST00000684046.1
ENST00000684476.1
ENST00000619550.5
ENST00000682169.1
hepatocyte nuclear factor 4 alpha
chr6_-_35512863 0.35 ENST00000428978.1
ENST00000614066.4
ENST00000322263.8
TUB like protein 1
chr17_-_29180377 0.35 ENST00000527372.7
myosin XVIIIA
chr12_-_118372883 0.33 ENST00000542532.5
ENST00000392533.8
TAO kinase 3
chr6_+_42929127 0.33 ENST00000394142.7
canopy FGF signaling regulator 3
chr20_+_31475278 0.33 ENST00000201979.3
RRAD and GEM like GTPase 1
chr7_-_27180230 0.32 ENST00000396344.4
homeobox A10
chr6_+_42929430 0.31 ENST00000372836.5
canopy FGF signaling regulator 3
chrX_-_18354672 0.31 ENST00000251900.9
Scm polycomb group protein like 2
chr22_-_38088915 0.30 ENST00000428572.1
BAR/IMD domain containing adaptor protein 2 like 2
chr7_-_100656384 0.29 ENST00000461605.1
ENST00000160382.10
actin like 6B
chr7_+_151051201 0.29 ENST00000490540.1
acid sensing ion channel subunit 3
chr6_-_35512882 0.28 ENST00000229771.11
TUB like protein 1
chr7_-_5530581 0.28 ENST00000676397.1
ENST00000645576.1
ENST00000674681.1
ENST00000646664.1
ENST00000493945.6
ENST00000676319.1
ENST00000473257.3
ENST00000647275.1
ENST00000432588.6
actin beta
chr14_-_93115812 0.28 ENST00000553452.5
inositol-tetrakisphosphate 1-kinase
chr4_-_119627631 0.26 ENST00000264805.9
phosphodiesterase 5A
chr11_-_64742937 0.26 ENST00000394428.5
ENST00000394429.5
RAS guanyl releasing protein 2
chr18_-_63318674 0.25 ENST00000589955.2
BCL2 apoptosis regulator
chrX_+_137566119 0.24 ENST00000287538.10
Zic family member 3
chr3_+_9917074 0.24 ENST00000416074.6
ENST00000383812.9
ENST00000438091.5
ENST00000295981.7
ENST00000403601.8
ENST00000436503.5
ENST00000455057.5
interleukin 17 receptor C
chr19_-_49867251 0.24 ENST00000631020.2
ENST00000596014.5
ENST00000636994.1
polynucleotide kinase 3'-phosphatase
chr8_-_132481057 0.23 ENST00000388996.10
potassium voltage-gated channel subfamily Q member 3
chr9_-_39239174 0.23 ENST00000358144.6
contactin associated protein family member 3
chr15_-_75368578 0.22 ENST00000569482.5
ENST00000565683.5
ENST00000561615.1
ENST00000563622.5
ENST00000568374.5
ENST00000267978.10
ENST00000566256.5
mannosidase alpha class 2C member 1
chr19_+_48393657 0.22 ENST00000263269.4
glutamate ionotropic receptor NMDA type subunit 2D
chr5_-_176630364 0.22 ENST00000310112.7
synuclein beta
chr19_+_19900935 0.21 ENST00000588146.1
ENST00000343769.6
zinc finger protein 93
chr7_-_100158679 0.21 ENST00000456769.5
ENST00000316937.8
trafficking protein particle complex 14
chr3_+_138349209 0.21 ENST00000474559.1
muscle RAS oncogene homolog
chr1_+_26317950 0.21 ENST00000374213.3
CD52 molecule
chr6_-_90586883 0.20 ENST00000369325.7
ENST00000369327.7
mitogen-activated protein kinase kinase kinase 7
chr10_+_123154414 0.19 ENST00000368858.9
BUB3 mitotic checkpoint protein
chr16_-_11587162 0.18 ENST00000570904.5
ENST00000574701.5
lipopolysaccharide induced TNF factor
chr11_-_63015804 0.18 ENST00000535878.5
ENST00000545207.5
solute carrier family 22 member 8
chr17_-_44376169 0.17 ENST00000587295.5
integrin subunit alpha 2b
chr6_-_90587018 0.17 ENST00000369332.7
ENST00000369329.8
mitogen-activated protein kinase kinase kinase 7
chr6_+_168441170 0.17 ENST00000356284.7
SPARC related modular calcium binding 2
chr6_+_168441136 0.16 ENST00000354536.9
SPARC related modular calcium binding 2
chr7_+_20330893 0.16 ENST00000222573.5
integrin subunit beta 8
chr10_+_123154768 0.16 ENST00000407911.2
BUB3 mitotic checkpoint protein
chr13_-_46052712 0.16 ENST00000242848.8
ENST00000679008.1
ENST00000282007.7
zinc finger CCCH-type containing 13
chr11_+_832887 0.15 ENST00000524748.6
ENST00000397420.9
ENST00000397421.5
ENST00000322008.9
ENST00000525718.6
ENST00000529810.5
ENST00000526693.5
ENST00000525333.5
ENST00000527341.5
CD151 molecule (Raph blood group)
chr3_+_9917185 0.15 ENST00000413608.2
ENST00000451165.6
interleukin 17 receptor C
chr11_-_63015831 0.14 ENST00000430500.6
ENST00000336232.7
solute carrier family 22 member 8
chr20_+_23035312 0.14 ENST00000255008.5
somatostatin receptor 4
chr5_-_176630517 0.14 ENST00000393693.7
ENST00000614675.4
synuclein beta
chr4_+_70704713 0.14 ENST00000417478.6
RUN and FYVE domain containing 3
chr16_-_70685791 0.14 ENST00000616026.4
MTSS I-BAR domain containing 2
chr6_+_30163188 0.11 ENST00000619857.4
tripartite motif containing 15
chr9_-_16870662 0.10 ENST00000380672.9
basonuclin 2
chr4_-_119628007 0.10 ENST00000420633.1
ENST00000394439.5
phosphodiesterase 5A
chr9_+_136982993 0.10 ENST00000408973.3
lipocalin like 1
chr1_+_1471751 0.07 ENST00000673477.1
ENST00000308647.8
ATPase family AAA domain containing 3B
chr13_+_51222391 0.06 ENST00000322475.13
family with sequence similarity 124 member A
chr1_-_32901330 0.06 ENST00000329151.5
ENST00000373463.8
transmembrane protein 54
chr9_-_16870702 0.06 ENST00000380667.6
ENST00000545497.5
ENST00000486514.5
basonuclin 2
chr19_-_4066892 0.05 ENST00000322357.9
zinc finger and BTB domain containing 7A
chr4_-_165112852 0.05 ENST00000505095.1
ENST00000306480.11
transmembrane protein 192
chr14_-_93115869 0.05 ENST00000556603.6
ENST00000354313.7
ENST00000267615.11
inositol-tetrakisphosphate 1-kinase
chr17_+_79024142 0.05 ENST00000579760.6
ENST00000339142.6
C1q and TNF related 1
chr19_-_35900532 0.05 ENST00000396901.5
ENST00000641389.2
ENST00000585925.7
NFKB inhibitor delta
chr17_-_81239025 0.05 ENST00000637944.2
TEPSIN adaptor related protein complex 4 accessory protein
chrX_+_30247139 0.04 ENST00000397548.4
MAGE family member B1
chr11_-_63917129 0.03 ENST00000301459.5
REST corepressor 2
chr5_+_69492767 0.03 ENST00000681041.1
ENST00000680098.1
ENST00000680784.1
ENST00000396442.7
ENST00000681895.1
occludin
chr2_+_170929198 0.03 ENST00000234160.5
golgi reassembly stacking protein 2
chr15_-_89751292 0.02 ENST00000300057.4
mesoderm posterior bHLH transcription factor 1
chr1_+_53062052 0.02 ENST00000395871.7
ENST00000673702.1
ENST00000673956.1
ENST00000312553.10
ENST00000371500.8
ENST00000618387.1
podocan
chr2_-_206086057 0.02 ENST00000403263.6
INO80 complex subunit D
chr20_+_58888779 0.01 ENST00000488546.6
ENST00000667293.2
ENST00000481039.6
ENST00000467321.6
GNAS complex locus
chr8_-_143160603 0.00 ENST00000615409.1
ENST00000414417.6
lymphocyte antigen 6 family member H

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0046732 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.5 2.9 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.5 2.3 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.3 1.6 GO:0071543 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.3 1.3 GO:0045337 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.2 0.7 GO:1903028 positive regulation of opsonization(GO:1903028)
0.2 0.9 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.2 2.0 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 1.0 GO:0010193 response to ozone(GO:0010193)
0.2 4.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 0.9 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.2 4.0 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.2 1.2 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 1.0 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.5 GO:1990834 negative regulation of T-helper 1 cell differentiation(GO:0045626) response to odorant(GO:1990834)
0.1 0.9 GO:0072103 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.1 0.5 GO:0006258 UDP-glucose catabolic process(GO:0006258) negative regulation of type B pancreatic cell development(GO:2000077)
0.1 0.7 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.1 0.3 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 0.5 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1 0.3 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.6 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.1 0.4 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.1 1.1 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.1 2.0 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 0.2 GO:0070893 transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895)
0.1 0.6 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 1.0 GO:0060346 bone trabecula formation(GO:0060346)
0.1 0.6 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 1.4 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.1 0.2 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.3 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.4 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.5 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 1.1 GO:0045821 positive regulation of glycolytic process(GO:0045821)
0.0 0.2 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.0 0.8 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.5 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.4 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.5 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.7 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 1.3 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.6 GO:0060022 hard palate development(GO:0060022)
0.0 0.3 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 2.4 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 0.1 GO:1901253 mesodermal cell fate determination(GO:0007500) negative regulation of intracellular transport of viral material(GO:1901253)
0.0 0.1 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.9 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.6 GO:0051412 response to corticosterone(GO:0051412)
0.0 0.4 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.4 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 1.4 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.8 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.3 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.0 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.7 GO:0021696 cerebellar cortex morphogenesis(GO:0021696)
0.0 0.2 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.4 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 1.9 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.0 GO:0003129 heart induction(GO:0003129)
0.0 1.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.3 GO:0060065 uterus development(GO:0060065)
0.0 1.7 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 1.1 GO:0001578 microtubule bundle formation(GO:0001578)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.1 0.7 GO:0032279 asymmetric synapse(GO:0032279)
0.1 0.4 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.8 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.7 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.4 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 1.4 GO:0005921 gap junction(GO:0005921)
0.0 0.9 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.0 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.6 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.5 GO:0005685 U1 snRNP(GO:0005685)
0.0 2.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.3 GO:0097433 dense body(GO:0097433)
0.0 0.3 GO:0071439 clathrin complex(GO:0071439)
0.0 2.6 GO:0043679 axon terminus(GO:0043679)
0.0 0.1 GO:0098560 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.0 2.1 GO:0005604 basement membrane(GO:0005604)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 4.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.2 GO:0033268 node of Ranvier(GO:0033268)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.4 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.4 2.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.4 1.4 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.3 1.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.3 1.6 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.3 1.0 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.3 1.3 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.2 2.9 GO:0008430 selenium binding(GO:0008430)
0.2 0.9 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.2 1.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.2 0.7 GO:0004998 transferrin receptor activity(GO:0004998)
0.2 2.0 GO:0043426 MRF binding(GO:0043426)
0.2 0.7 GO:0070905 serine binding(GO:0070905)
0.2 0.8 GO:0043515 kinetochore binding(GO:0043515)
0.2 2.3 GO:0008199 ferric iron binding(GO:0008199)
0.1 0.5 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.3 GO:0052835 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.1 0.5 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.3 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 2.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 2.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.2 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 1.1 GO:0048185 activin binding(GO:0048185)
0.1 1.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.9 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 1.6 GO:0019956 chemokine binding(GO:0019956)
0.0 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.0 1.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 4.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.4 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 1.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.5 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.1 PID BMP PATHWAY BMP receptor signaling
0.0 0.7 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.3 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 ST GAQ PATHWAY G alpha q Pathway
0.0 3.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 3.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.9 PID NOTCH PATHWAY Notch signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.2 4.0 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 2.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.4 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 0.9 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 1.0 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 0.4 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.5 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.6 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 1.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 2.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.2 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.8 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 1.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.9 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 2.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.5 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.6 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.7 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins