Project

GSE58827: Dynamics of the Mouse Liver

Navigation
Downloads

Results for AGCAGCG

Z-value: 0.31

Motif logo

logo of

miRNA associated with seed AGCAGCG

NamemiRBASE accession
mmu-miR-503-5p
MIMAT0003188

Activity profile of AGCAGCG motif

Sorted Z-values of AGCAGCG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_114131229 1.13 ENSMUST00000032451.7
Slc6a11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr7_-_38107490 0.97 ENSMUST00000108023.3
Ccne1
cyclin E1
chr2_-_165473187 0.84 ENSMUST00000029208.8
ENSMUST00000109279.2
Slc13a3
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
chr6_-_91411341 0.51 ENSMUST00000032180.6
Wnt7a
wingless-related MMTV integration site 7A
chr9_-_61946768 0.46 ENSMUST00000034815.7
Kif23
kinesin family member 23
chr9_-_36726374 0.45 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
Chek1
checkpoint kinase 1
chr11_-_87108656 0.37 ENSMUST00000051395.8
Prr11
proline rich 11
chr1_-_98095596 0.37 ENSMUST00000058762.8
ENSMUST00000097625.3
Pam
peptidylglycine alpha-amidating monooxygenase
chr19_+_4711153 0.33 ENSMUST00000008991.6
Sptbn2
spectrin beta, non-erythrocytic 2
chr1_-_152090308 0.33 ENSMUST00000044581.7
1700025G04Rik
RIKEN cDNA 1700025G04 gene
chr7_+_67952817 0.32 ENSMUST00000005671.8
Igf1r
insulin-like growth factor I receptor
chrX_-_48034842 0.31 ENSMUST00000039026.7
Apln
apelin
chr7_+_110122299 0.30 ENSMUST00000033326.8
Wee1
WEE 1 homolog 1 (S. pombe)
chr17_-_46629420 0.30 ENSMUST00000044442.8
Ptk7
PTK7 protein tyrosine kinase 7
chr17_-_31855782 0.30 ENSMUST00000024839.4
Sik1
salt inducible kinase 1
chr5_-_99252839 0.30 ENSMUST00000168092.1
ENSMUST00000031276.8
Rasgef1b
RasGEF domain family, member 1B
chr2_+_179442427 0.29 ENSMUST00000000314.6
Cdh4
cadherin 4
chr10_+_13090788 0.29 ENSMUST00000121646.1
ENSMUST00000121325.1
ENSMUST00000121766.1
Plagl1
pleiomorphic adenoma gene-like 1
chr5_+_47984793 0.25 ENSMUST00000170109.2
ENSMUST00000174421.1
ENSMUST00000173702.1
ENSMUST00000173107.1
Slit2
slit homolog 2 (Drosophila)
chr1_-_21961581 0.23 ENSMUST00000029667.6
ENSMUST00000173058.1
ENSMUST00000173404.1
Kcnq5
potassium voltage-gated channel, subfamily Q, member 5
chr4_+_139574697 0.23 ENSMUST00000174078.1
Iffo2
intermediate filament family orphan 2
chr4_+_114406717 0.23 ENSMUST00000094894.3
Trabd2b
TraB domain containing 2B
chr5_-_89883321 0.21 ENSMUST00000163159.1
ENSMUST00000061427.5
Adamts3
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3
chr8_+_88521344 0.21 ENSMUST00000034086.5
Nkd1
naked cuticle 1 homolog (Drosophila)
chr7_+_18925863 0.21 ENSMUST00000172835.1
ENSMUST00000032571.8
Nova2
neuro-oncological ventral antigen 2
chr4_-_155222535 0.21 ENSMUST00000084103.3
ENSMUST00000030917.5
Ski
ski sarcoma viral oncogene homolog (avian)
chr14_-_31577318 0.21 ENSMUST00000112027.2
Colq
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr2_+_68117713 0.20 ENSMUST00000112346.2
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr10_-_29535857 0.20 ENSMUST00000092623.3
Rspo3
R-spondin 3 homolog (Xenopus laevis)
chr8_-_77724426 0.20 ENSMUST00000034029.7
Ednra
endothelin receptor type A
chr14_+_75016027 0.19 ENSMUST00000036072.7
5031414D18Rik
RIKEN cDNA 5031414D18 gene
chr15_+_103240405 0.19 ENSMUST00000036004.9
ENSMUST00000087351.7
Hnrnpa1
heterogeneous nuclear ribonucleoprotein A1
chr5_+_88886809 0.19 ENSMUST00000148750.1
Slc4a4
solute carrier family 4 (anion exchanger), member 4
chr8_+_83900096 0.19 ENSMUST00000141158.1
Lphn1
latrophilin 1
chr11_-_119086221 0.17 ENSMUST00000026665.7
Cbx4
chromobox 4
chr5_+_113490447 0.15 ENSMUST00000094452.3
Wscd2
WSC domain containing 2
chr12_-_112829351 0.15 ENSMUST00000062092.5
Cdca4
cell division cycle associated 4
chr4_+_137277489 0.15 ENSMUST00000045747.4
Wnt4
wingless-related MMTV integration site 4
chr4_+_43875524 0.15 ENSMUST00000030198.6
Reck
reversion-inducing-cysteine-rich protein with kazal motifs
chr13_+_47122719 0.15 ENSMUST00000068891.4
Rnf144b
ring finger protein 144B
chr14_+_55854115 0.14 ENSMUST00000168479.1
Nynrin
NYN domain and retroviral integrase containing
chr1_-_37541003 0.14 ENSMUST00000151952.1
Mgat4a
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr1_-_135585314 0.14 ENSMUST00000040599.8
ENSMUST00000067414.6
Nav1
neuron navigator 1
chr10_-_127060163 0.14 ENSMUST00000040307.5
March9
membrane-associated ring finger (C3HC4) 9
chr5_-_93045022 0.14 ENSMUST00000061328.5
Sowahb
sosondowah ankyrin repeat domain family member B
chr9_-_53975246 0.14 ENSMUST00000048409.7
Elmod1
ELMO/CED-12 domain containing 1
chr4_+_65124174 0.13 ENSMUST00000084501.3
Pappa
pregnancy-associated plasma protein A
chr19_+_45363734 0.13 ENSMUST00000065601.5
ENSMUST00000111936.2
Btrc
beta-transducin repeat containing protein
chr3_+_98382438 0.11 ENSMUST00000056096.8
Zfp697
zinc finger protein 697
chr8_-_86885222 0.11 ENSMUST00000034074.7
N4bp1
NEDD4 binding protein 1
chr9_-_108190352 0.11 ENSMUST00000035208.7
Bsn
bassoon
chr8_-_120589304 0.11 ENSMUST00000034278.5
Gins2
GINS complex subunit 2 (Psf2 homolog)
chr9_-_58159201 0.11 ENSMUST00000041477.7
Islr
immunoglobulin superfamily containing leucine-rich repeat
chr1_-_106714217 0.11 ENSMUST00000112751.1
Bcl2
B cell leukemia/lymphoma 2
chr4_-_141790891 0.11 ENSMUST00000038014.4
ENSMUST00000153880.1
Dnajc16
DnaJ (Hsp40) homolog, subfamily C, member 16
chr15_-_9529868 0.10 ENSMUST00000003981.4
Il7r
interleukin 7 receptor
chr4_+_115839192 0.10 ENSMUST00000019677.5
ENSMUST00000144427.1
ENSMUST00000106513.3
ENSMUST00000130819.1
ENSMUST00000151203.1
ENSMUST00000140315.1
Mknk1
MAP kinase-interacting serine/threonine kinase 1
chr1_+_86045863 0.10 ENSMUST00000165824.1
2810459M11Rik
RIKEN cDNA 2810459M11 gene
chr7_-_118491912 0.09 ENSMUST00000178344.1
Itpripl2
inositol 1,4,5-triphosphate receptor interacting protein-like 2
chr14_-_65098031 0.09 ENSMUST00000022550.7
Extl3
exostoses (multiple)-like 3
chr6_-_127151044 0.09 ENSMUST00000000188.8
Ccnd2
cyclin D2
chr13_-_101768154 0.09 ENSMUST00000055518.6
Pik3r1
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
chr19_+_10688744 0.09 ENSMUST00000087951.5
Vps37c
vacuolar protein sorting 37C (yeast)
chr10_+_128411616 0.08 ENSMUST00000096386.5
ENSMUST00000171342.1
Rnf41
ring finger protein 41
chr5_-_5514730 0.08 ENSMUST00000115445.1
ENSMUST00000179804.1
ENSMUST00000125110.1
ENSMUST00000115446.1
Cldn12
claudin 12
chr15_+_84923383 0.08 ENSMUST00000165443.2
Nup50
nucleoporin 50
chr11_-_63922257 0.08 ENSMUST00000094103.3
Hs3st3b1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr6_+_47877204 0.08 ENSMUST00000061890.7
Zfp282
zinc finger protein 282
chr8_+_22476700 0.07 ENSMUST00000067786.7
Slc20a2
solute carrier family 20, member 2
chr17_+_47505117 0.07 ENSMUST00000183044.1
ENSMUST00000037333.10
Ccnd3
cyclin D3
chr13_+_44731265 0.07 ENSMUST00000173246.1
Jarid2
jumonji, AT rich interactive domain 2
chr2_-_160872552 0.07 ENSMUST00000103111.2
Zhx3
zinc fingers and homeoboxes 3
chr8_-_122699066 0.07 ENSMUST00000127984.1
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr9_+_43744399 0.06 ENSMUST00000034510.7
Pvrl1
poliovirus receptor-related 1
chr1_+_60746358 0.06 ENSMUST00000027165.2
Cd28
CD28 antigen
chr12_-_108003594 0.05 ENSMUST00000066060.4
Bcl11b
B cell leukemia/lymphoma 11B
chr8_+_105900421 0.05 ENSMUST00000049699.8
Pskh1
protein serine kinase H1
chr4_+_101419277 0.05 ENSMUST00000102780.1
ENSMUST00000106946.1
ENSMUST00000106945.1
Ak4
adenylate kinase 4
chr7_-_97738222 0.04 ENSMUST00000084986.6
Aqp11
aquaporin 11
chr13_-_103764502 0.04 ENSMUST00000074616.5
Srek1
splicing regulatory glutamine/lysine-rich protein 1
chr2_-_30124454 0.04 ENSMUST00000044751.8
Zer1
zyg-11 related, cell cycle regulator
chr15_-_103239812 0.04 ENSMUST00000118152.1
Cbx5
chromobox 5
chr3_+_58415689 0.03 ENSMUST00000099090.2
Tsc22d2
TSC22 domain family, member 2
chr1_-_75479271 0.03 ENSMUST00000079205.7
ENSMUST00000094818.2
Chpf
chondroitin polymerizing factor
chr4_-_136835843 0.03 ENSMUST00000105846.2
ENSMUST00000059287.7
ENSMUST00000105845.2
Ephb2
Eph receptor B2
chr11_+_106036867 0.03 ENSMUST00000058438.8
Dcaf7
DDB1 and CUL4 associated factor 7
chr5_-_144965793 0.03 ENSMUST00000110677.1
ENSMUST00000085684.4
ENSMUST00000100461.2
Smurf1
SMAD specific E3 ubiquitin protein ligase 1
chr19_-_19001099 0.03 ENSMUST00000040153.8
ENSMUST00000112828.1
Rorb
RAR-related orphan receptor beta
chr10_+_127739516 0.02 ENSMUST00000054287.7
Zbtb39
zinc finger and BTB domain containing 39
chrX_+_36328353 0.02 ENSMUST00000016383.3
Lonrf3
LON peptidase N-terminal domain and ring finger 3
chr7_+_101108768 0.02 ENSMUST00000098250.3
ENSMUST00000032931.7
Fchsd2
FCH and double SH3 domains 2
chr2_-_39065438 0.02 ENSMUST00000112850.2
Golga1
golgi autoantigen, golgin subfamily a, 1
chr16_-_46010212 0.02 ENSMUST00000130481.1
Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr1_+_64690443 0.01 ENSMUST00000114077.1
Ccnyl1
cyclin Y-like 1
chr5_-_146795002 0.01 ENSMUST00000085614.5
Usp12
ubiquitin specific peptidase 12
chr11_+_107547925 0.01 ENSMUST00000100305.1
ENSMUST00000075012.1
ENSMUST00000106746.1
Helz
helicase with zinc finger domain
chr15_+_25984359 0.01 ENSMUST00000061875.6
Zfp622
zinc finger protein 622
chr7_+_122067164 0.01 ENSMUST00000033158.4
Ubfd1
ubiquitin family domain containing 1
chr8_+_106935720 0.01 ENSMUST00000047425.3
Sntb2
syntrophin, basic 2
chr19_-_60581013 0.01 ENSMUST00000111460.3
ENSMUST00000081790.7
ENSMUST00000166712.1
Cacul1
CDK2 associated, cullin domain 1
chr13_+_49421229 0.01 ENSMUST00000021817.8
Ippk
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr19_+_8953826 0.00 ENSMUST00000096239.5
Tut1
terminal uridylyl transferase 1, U6 snRNA-specific
chr11_-_70669283 0.00 ENSMUST00000129434.1
ENSMUST00000018431.6
Spag7
sperm associated antigen 7

Network of associatons between targets according to the STRING database.

First level regulatory network of AGCAGCG

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0015744 succinate transport(GO:0015744)
0.2 0.5 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.3 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466) regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.5 GO:0060066 oviduct development(GO:0060066)
0.1 0.3 GO:0050924 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.1 0.3 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.2 GO:0072034 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748) renal vesicle induction(GO:0072034) negative regulation of male gonad development(GO:2000019)
0.1 0.5 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.3 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.4 GO:0031179 peptide modification(GO:0031179)
0.0 0.1 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.0 0.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.2 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.2 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.2 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.0 0.2 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 1.1 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.3 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:0006808 regulation of nitrogen utilization(GO:0006808) nitrogen utilization(GO:0019740) regulation of cellular pH reduction(GO:0032847)
0.0 0.2 GO:0018158 protein oxidation(GO:0018158)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.0 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.0 0.2 GO:0042482 artery smooth muscle contraction(GO:0014824) positive regulation of odontogenesis(GO:0042482)
0.0 0.3 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.1 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.0 GO:0072014 proximal tubule development(GO:0072014)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 1.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.2 1.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2 0.5 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.3 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.1 0.4 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.2 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.4 GO:0043559 insulin binding(GO:0043559)
0.0 0.3 GO:0048495 GTPase inhibitor activity(GO:0005095) Roundabout binding(GO:0048495)
0.0 0.1 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 1.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.4 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.0 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 1.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.0 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling