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GSE58827: Dynamics of the Mouse Liver

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Results for AGGUAGU

Z-value: 0.88

Motif logo

logo of

miRNA associated with seed AGGUAGU

NamemiRBASE accession
mmu-miR-196a-5p
MIMAT0000518
mmu-miR-196b-5p
MIMAT0001081

Activity profile of AGGUAGU motif

Sorted Z-values of AGGUAGU motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_65101453 8.44 ENSMUST00000077696.6
ENSMUST00000035499.4
ENSMUST00000166273.1
Igdcc4
immunoglobulin superfamily, DCC subclass, member 4
chr11_-_96005872 8.26 ENSMUST00000013559.2
Igf2bp1
insulin-like growth factor 2 mRNA binding protein 1
chr10_-_45470201 5.68 ENSMUST00000079390.6
Lin28b
lin-28 homolog B (C. elegans)
chrX_+_93654863 5.14 ENSMUST00000113933.2
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chr4_-_134018829 4.16 ENSMUST00000051674.2
Lin28a
lin-28 homolog A (C. elegans)
chr6_-_49214954 4.09 ENSMUST00000031838.7
Igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
chr2_-_152415044 3.96 ENSMUST00000099207.3
Zcchc3
zinc finger, CCHC domain containing 3
chr1_+_86303221 3.50 ENSMUST00000113306.2
B3gnt7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr6_-_52226165 3.24 ENSMUST00000114425.2
Hoxa9
homeobox A9
chr11_+_44617310 2.99 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
Ebf1
early B cell factor 1
chr13_+_35659856 2.97 ENSMUST00000075220.6
Cdyl
chromodomain protein, Y chromosome-like
chr7_+_120842824 2.72 ENSMUST00000047875.8
Eef2k
eukaryotic elongation factor-2 kinase
chr4_+_140700487 2.72 ENSMUST00000071169.2
Rcc2
regulator of chromosome condensation 2
chr13_-_117025505 2.61 ENSMUST00000022239.6
Parp8
poly (ADP-ribose) polymerase family, member 8
chr10_+_117629493 2.50 ENSMUST00000020399.5
Cpm
carboxypeptidase M
chr10_-_120476469 2.49 ENSMUST00000072777.7
ENSMUST00000159699.1
Hmga2
high mobility group AT-hook 2
chr9_-_123632545 2.34 ENSMUST00000026273.8
Slc6a20b
solute carrier family 6 (neurotransmitter transporter), member 20B
chr2_+_31245801 2.32 ENSMUST00000000199.7
Ncs1
neuronal calcium sensor 1
chr17_+_27556613 2.08 ENSMUST00000117600.1
ENSMUST00000114888.3
Hmga1
high mobility group AT-hook 1
chr1_-_37541003 2.05 ENSMUST00000151952.1
Mgat4a
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr6_-_145048809 1.98 ENSMUST00000032402.5
Bcat1
branched chain aminotransferase 1, cytosolic
chr6_+_4747306 1.96 ENSMUST00000175823.1
ENSMUST00000176204.1
ENSMUST00000166678.1
Peg10
paternally expressed 10
chr17_-_26095487 1.96 ENSMUST00000025007.5
Nme4
NME/NM23 nucleoside diphosphate kinase 4
chr3_+_145292472 1.94 ENSMUST00000029848.4
ENSMUST00000139001.1
Col24a1
collagen, type XXIV, alpha 1
chrX_-_133688978 1.93 ENSMUST00000149154.1
ENSMUST00000167944.1
Pcdh19
protocadherin 19
chr10_-_123196916 1.78 ENSMUST00000020334.7
Usp15
ubiquitin specific peptidase 15
chr1_-_191026181 1.72 ENSMUST00000085635.4
Mfsd7b
major facilitator superfamily domain containing 7B
chr9_+_72806874 1.67 ENSMUST00000055535.8
Prtg
protogenin homolog (Gallus gallus)
chrX_-_48454152 1.64 ENSMUST00000114958.1
Elf4
E74-like factor 4 (ets domain transcription factor)
chr7_+_16130285 1.50 ENSMUST00000168693.1
Slc8a2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr2_+_112379204 1.42 ENSMUST00000028552.3
Katnbl1
katanin p80 subunit B like 1
chr11_+_94936224 1.32 ENSMUST00000001547.7
Col1a1
collagen, type I, alpha 1
chr1_-_135105210 1.25 ENSMUST00000044828.7
Lgr6
leucine-rich repeat-containing G protein-coupled receptor 6
chr10_+_58446845 1.18 ENSMUST00000003310.5
Ranbp2
RAN binding protein 2
chr16_+_33062512 1.16 ENSMUST00000023497.2
Lmln
leishmanolysin-like (metallopeptidase M8 family)
chr15_+_11064764 1.07 ENSMUST00000061318.7
Adamts12
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 12
chr6_-_52217505 1.07 ENSMUST00000048715.6
Hoxa7
homeobox A7
chr19_-_7383026 1.04 ENSMUST00000025924.2
AI846148
expressed sequence AI846148
chr17_-_68004075 1.03 ENSMUST00000024840.5
Arhgap28
Rho GTPase activating protein 28
chr8_-_90348343 1.02 ENSMUST00000109621.3
Tox3
TOX high mobility group box family member 3
chr13_+_45507438 1.02 ENSMUST00000000260.6
Gmpr
guanosine monophosphate reductase
chr6_+_4505493 1.01 ENSMUST00000031668.8
Col1a2
collagen, type I, alpha 2
chr8_-_122699066 0.95 ENSMUST00000127984.1
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr7_-_16924114 0.92 ENSMUST00000019514.9
Calm3
calmodulin 3
chr4_+_28813125 0.89 ENSMUST00000029964.5
ENSMUST00000080934.4
Epha7
Eph receptor A7
chr2_-_93334467 0.89 ENSMUST00000111265.2
Tspan18
tetraspanin 18
chr3_+_68468162 0.89 ENSMUST00000182532.1
Schip1
schwannomin interacting protein 1
chr6_+_134920401 0.86 ENSMUST00000067327.4
ENSMUST00000003115.6
Cdkn1b
cyclin-dependent kinase inhibitor 1B
chr1_+_130717320 0.85 ENSMUST00000049813.4
Yod1
YOD1 OTU deubiquitinating enzyme 1 homologue (S. cerevisiae)
chr8_-_105827190 0.83 ENSMUST00000041400.5
Ranbp10
RAN binding protein 10
chr2_-_152398046 0.80 ENSMUST00000063332.8
ENSMUST00000182625.1
Sox12
SRY-box containing gene 12
chr5_-_124095749 0.79 ENSMUST00000031354.4
Abcb9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr14_-_49066653 0.74 ENSMUST00000162175.1
Exoc5
exocyst complex component 5
chr5_-_107289561 0.69 ENSMUST00000031224.8
Tgfbr3
transforming growth factor, beta receptor III
chr16_+_37916440 0.68 ENSMUST00000061274.7
Gpr156
G protein-coupled receptor 156
chr15_+_102990576 0.68 ENSMUST00000001703.6
Hoxc8
homeobox C8
chr11_-_115603866 0.64 ENSMUST00000125097.1
ENSMUST00000106508.3
ENSMUST00000019135.7
Gga3
golgi associated, gamma adaptin ear containing, ARF binding protein 3
chr9_+_27790947 0.63 ENSMUST00000115243.2
Opcml
opioid binding protein/cell adhesion molecule-like
chr8_-_47352348 0.60 ENSMUST00000110367.2
Stox2
storkhead box 2
chrX_+_138914422 0.60 ENSMUST00000064937.7
ENSMUST00000113052.1
Nrk
Nik related kinase
chr5_+_13399309 0.59 ENSMUST00000030714.7
ENSMUST00000141968.1
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr13_-_111808938 0.59 ENSMUST00000109267.2
Map3k1
mitogen-activated protein kinase kinase kinase 1
chr14_-_105176860 0.58 ENSMUST00000163545.1
Rbm26
RNA binding motif protein 26
chr16_+_87698904 0.57 ENSMUST00000026703.5
Bach1
BTB and CNC homology 1
chr11_-_57832679 0.57 ENSMUST00000160392.2
ENSMUST00000108845.2
Hand1
heart and neural crest derivatives expressed transcript 1
chr15_+_6708372 0.56 ENSMUST00000061656.6
Rictor
RPTOR independent companion of MTOR, complex 2
chr5_-_135545108 0.55 ENSMUST00000060311.8
Hip1
huntingtin interacting protein 1
chr11_-_88718223 0.54 ENSMUST00000107909.1
Msi2
musashi RNA-binding protein 2
chr6_-_52204415 0.53 ENSMUST00000048794.6
Hoxa5
homeobox A5
chr12_-_27342696 0.50 ENSMUST00000079063.5
Sox11
SRY-box containing gene 11
chr11_+_54303798 0.48 ENSMUST00000093106.5
Acsl6
acyl-CoA synthetase long-chain family member 6
chr17_+_31057686 0.48 ENSMUST00000024829.6
Abcg1
ATP-binding cassette, sub-family G (WHITE), member 1
chr18_+_12128850 0.48 ENSMUST00000025270.6
Riok3
RIO kinase 3
chr7_+_44442398 0.47 ENSMUST00000058667.8
Lrrc4b
leucine rich repeat containing 4B
chr12_-_34528844 0.46 ENSMUST00000110819.2
Hdac9
histone deacetylase 9
chrX_+_153237748 0.44 ENSMUST00000112574.2
Klf8
Kruppel-like factor 8
chr9_-_50617428 0.44 ENSMUST00000131351.1
ENSMUST00000171462.1
AU019823
expressed sequence AU019823
chr10_-_76345254 0.43 ENSMUST00000036033.7
ENSMUST00000160048.1
ENSMUST00000105417.3
Dip2a
DIP2 disco-interacting protein 2 homolog A (Drosophila)
chr1_-_155972887 0.41 ENSMUST00000138762.1
ENSMUST00000124495.1
Cep350
centrosomal protein 350
chr4_+_21931291 0.37 ENSMUST00000029908.7
Faxc
failed axon connections homolog (Drosophila)
chr2_-_34372004 0.36 ENSMUST00000113132.2
ENSMUST00000040638.8
Pbx3
pre B cell leukemia homeobox 3
chr6_-_127151044 0.36 ENSMUST00000000188.8
Ccnd2
cyclin D2
chr9_-_117252450 0.33 ENSMUST00000111773.3
ENSMUST00000068962.7
ENSMUST00000044901.7
Rbms3
RNA binding motif, single stranded interacting protein
chr4_+_6365650 0.32 ENSMUST00000029912.4
ENSMUST00000103008.5
ENSMUST00000175769.1
ENSMUST00000108374.1
ENSMUST00000140830.1
Sdcbp
syndecan binding protein
chr18_+_31609512 0.31 ENSMUST00000164667.1
B930094E09Rik
RIKEN cDNA B930094E09 gene
chr2_+_60209887 0.30 ENSMUST00000102748.4
ENSMUST00000102747.1
March7
membrane-associated ring finger (C3HC4) 7
chr12_-_104751900 0.27 ENSMUST00000041987.6
Dicer1
dicer 1, ribonuclease type III
chr18_-_10181792 0.26 ENSMUST00000067947.5
Rock1
Rho-associated coiled-coil containing protein kinase 1
chr14_-_70443442 0.23 ENSMUST00000000793.5
Polr3d
polymerase (RNA) III (DNA directed) polypeptide D
chr8_-_110997764 0.22 ENSMUST00000040416.7
Ddx19a
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19a
chrX_-_7188713 0.20 ENSMUST00000004428.7
Clcn5
chloride channel 5
chr2_-_153529941 0.20 ENSMUST00000035346.7
8430427H17Rik
RIKEN cDNA 8430427H17 gene
chrX_-_104201126 0.20 ENSMUST00000056502.6
ENSMUST00000118314.1
C77370
expressed sequence C77370
chr10_-_23349887 0.20 ENSMUST00000074366.6
ENSMUST00000092665.4
Eya4
eyes absent 4 homolog (Drosophila)
chr8_-_84104773 0.19 ENSMUST00000041367.7
Dcaf15
DDB1 and CUL4 associated factor 15
chr19_+_40831248 0.19 ENSMUST00000025983.6
ENSMUST00000120057.1
Ccnj
cyclin J
chr1_+_93803945 0.19 ENSMUST00000027505.6
Ing5
inhibitor of growth family, member 5
chr10_+_127677064 0.18 ENSMUST00000118612.1
ENSMUST00000048099.4
Tmem194
transmembrane protein 194
chr19_+_23758819 0.18 ENSMUST00000025830.7
Apba1
amyloid beta (A4) precursor protein binding, family A, member 1
chr8_+_14095849 0.18 ENSMUST00000152652.1
ENSMUST00000133298.1
Dlgap2
discs, large (Drosophila) homolog-associated protein 2
chr8_-_91313223 0.16 ENSMUST00000047783.7
Rpgrip1l
Rpgrip1-like
chrX_-_21061981 0.16 ENSMUST00000040628.5
ENSMUST00000115333.2
ENSMUST00000115334.1
Zfp182
zinc finger protein 182
chr7_+_90426312 0.15 ENSMUST00000061391.7
Ccdc89
coiled-coil domain containing 89
chr8_-_111027752 0.15 ENSMUST00000040241.8
Ddx19b
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19b
chr6_+_92091378 0.14 ENSMUST00000113460.1
Nr2c2
nuclear receptor subfamily 2, group C, member 2
chr2_+_122738495 0.13 ENSMUST00000005954.8
Bloc1s6
biogenesis of organelles complex-1, subunit 6, pallidin
chr9_+_110132015 0.12 ENSMUST00000088716.5
ENSMUST00000111969.1
ENSMUST00000035057.7
ENSMUST00000111966.1
ENSMUST00000111968.1
Smarcc1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr15_-_43170809 0.12 ENSMUST00000063492.6
Rspo2
R-spondin 2 homolog (Xenopus laevis)
chr6_+_7844806 0.12 ENSMUST00000040159.4
C1galt1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr13_+_96924674 0.10 ENSMUST00000171324.1
Gcnt4
glucosaminyl (N-acetyl) transferase 4, core 2 (beta-1,6-N-acetylglucosaminyltransferase)
chr3_+_103058302 0.10 ENSMUST00000029445.6
Nras
neuroblastoma ras oncogene
chr12_-_91590009 0.09 ENSMUST00000021345.6
Gtf2a1
general transcription factor II A, 1
chr17_+_33929514 0.08 ENSMUST00000047503.9
Rgl2
ral guanine nucleotide dissociation stimulator-like 2
chr4_-_82859571 0.06 ENSMUST00000156055.1
ENSMUST00000030110.8
Zdhhc21
zinc finger, DHHC domain containing 21
chr4_+_86874396 0.06 ENSMUST00000045224.7
ENSMUST00000084433.4
Acer2
alkaline ceramidase 2
chr11_+_105589970 0.06 ENSMUST00000168598.1
ENSMUST00000100330.3
Tanc2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr12_-_11436607 0.05 ENSMUST00000072299.5
Vsnl1
visinin-like 1
chr1_-_134955908 0.04 ENSMUST00000045665.6
ENSMUST00000086444.4
ENSMUST00000112163.1
Ppp1r12b
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr9_+_111311674 0.04 ENSMUST00000078626.3
Trank1
tetratricopeptide repeat and ankyrin repeat containing 1
chr6_-_115994953 0.04 ENSMUST00000015511.8
Plxnd1
plexin D1
chr2_+_156196642 0.02 ENSMUST00000037401.8
Phf20
PHD finger protein 20
chr11_+_96292453 0.02 ENSMUST00000173432.1
Hoxb6
homeobox B6
chr6_-_120493807 0.01 ENSMUST00000178687.1
Cecr6
cat eye syndrome chromosome region, candidate 6
chrX_-_111697069 0.01 ENSMUST00000113422.2
ENSMUST00000038472.5
Hdx
highly divergent homeobox
chr2_+_154436437 0.00 ENSMUST00000109725.1
ENSMUST00000099178.3
ENSMUST00000045270.8
ENSMUST00000109724.1
Cbfa2t2
core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human)
chr3_-_10440054 0.00 ENSMUST00000099223.4
ENSMUST00000029047.6
Snx16
sorting nexin 16

Network of associatons between targets according to the STRING database.

First level regulatory network of AGGUAGU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 8.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
1.1 9.8 GO:0010587 miRNA catabolic process(GO:0010587)
0.5 2.7 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.4 1.2 GO:1990523 bone regeneration(GO:1990523)
0.4 1.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.4 1.8 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.3 2.0 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.3 1.5 GO:1990034 calcium ion export from cell(GO:1990034)
0.3 0.8 GO:1990168 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.3 2.5 GO:0060613 fat pad development(GO:0060613)
0.3 1.1 GO:0030167 proteoglycan catabolic process(GO:0030167) regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.3 1.0 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.2 1.6 GO:0001866 NK T cell proliferation(GO:0001866)
0.2 0.7 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.2 3.2 GO:0042118 endothelial cell activation(GO:0042118)
0.2 0.6 GO:0060720 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
0.2 0.6 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.2 1.3 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.2 0.5 GO:0060574 bronchiole development(GO:0060435) intestinal epithelial cell maturation(GO:0060574)
0.2 2.0 GO:0006228 UTP biosynthetic process(GO:0006228)
0.2 0.5 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 0.5 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.1 0.9 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 0.5 GO:0061386 closure of optic fissure(GO:0061386)
0.1 0.5 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 0.6 GO:0021824 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) facioacoustic ganglion development(GO:1903375)
0.1 0.6 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.9 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746) negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1 1.0 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 1.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 0.5 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.1 0.6 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 1.0 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.3 GO:0032290 peripheral nervous system myelin formation(GO:0032290) regulation of enamel mineralization(GO:0070173)
0.1 0.3 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.1 5.1 GO:0001541 ovarian follicle development(GO:0001541)
0.1 0.3 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.5 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 2.7 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 1.0 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 2.1 GO:0006284 base-excision repair(GO:0006284)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.9 GO:0001553 luteinization(GO:0001553)
0.0 0.1 GO:0048087 positive regulation of developmental pigmentation(GO:0048087) positive regulation of pigment cell differentiation(GO:0050942)
0.0 0.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.4 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 4.2 GO:0051028 mRNA transport(GO:0051028)
0.0 1.9 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.0 0.6 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.4 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 2.4 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.0 0.1 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.0 0.1 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.0 5.2 GO:0006486 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 0.4 GO:0034453 microtubule anchoring(GO:0034453)
0.0 1.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 0.3 GO:0002643 regulation of tolerance induction(GO:0002643)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 8.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.8 2.3 GO:0005584 collagen type I trimer(GO:0005584)
0.2 2.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.2 0.7 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.2 2.7 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 0.5 GO:0098888 extrinsic component of presynaptic membrane(GO:0098888)
0.1 2.3 GO:0031045 dense core granule(GO:0031045)
0.1 0.4 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 4.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.5 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.6 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.7 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 2.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 2.3 GO:0031526 brush border membrane(GO:0031526)
0.0 0.6 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 1.6 GO:0016605 PML body(GO:0016605)
0.0 1.3 GO:0005643 nuclear pore(GO:0005643)
0.0 2.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.9 2.7 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
0.5 4.2 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.4 12.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.3 2.0 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.3 1.8 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.3 4.6 GO:0003680 AT DNA binding(GO:0003680)
0.3 2.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 2.0 GO:1901612 cardiolipin binding(GO:1901612)
0.2 2.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 0.5 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.1 0.6 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 1.0 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.8 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 1.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 3.0 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 0.8 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.1 0.7 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 1.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.8 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 2.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 2.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.1 3.6 GO:0008378 galactosyltransferase activity(GO:0008378)
0.1 1.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.7 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.5 GO:0089720 caspase binding(GO:0089720)
0.1 0.6 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.3 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 0.9 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 1.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0045545 syndecan binding(GO:0045545)
0.0 0.6 GO:0045499 chemorepellent activity(GO:0045499)
0.0 1.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 2.7 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 2.7 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 1.2 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0 0.1 GO:0071633 dihydroceramidase activity(GO:0071633)
0.0 0.5 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 2.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 12.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 1.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 0.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 8.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 2.3 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 2.3 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 1.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.9 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.8 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.2 2.7 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 5.1 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.2 2.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 2.1 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 3.5 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 12.7 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.1 1.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 2.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 3.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.4 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 3.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.6 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.3 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.4 REACTOME G1 PHASE Genes involved in G1 Phase