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GSE58827: Dynamics of the Mouse Liver

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Results for Arid5b

Z-value: 0.45

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Transcription factors associated with Arid5b

Gene Symbol Gene ID Gene Info
Arid5b
ENSMUSG00000019947.9 AT rich interactive domain 5B (MRF1-like)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Arid5bmm10_v2_chr10_-_68278713_682787350.372.7e-02Click!

Activity profile of Arid5b motif

Sorted Z-values of Arid5b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_41458923 3.13 ENSMUST00000031910.7
Prss1
protease, serine, 1 (trypsin 1)
chr3_-_113532288 3.00 ENSMUST00000132353.1
Amy2a1
amylase 2a1
chr3_-_113258837 2.59 ENSMUST00000098673.3
Amy2a5
amylase 2a5
chr5_-_87337165 2.26 ENSMUST00000031195.2
Ugt2a3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr11_+_98383811 1.29 ENSMUST00000008021.2
Tcap
titin-cap
chr6_-_141946960 0.85 ENSMUST00000042119.5
Slco1a1
solute carrier organic anion transporter family, member 1a1
chr3_-_95882031 0.78 ENSMUST00000161994.1
Gm129
predicted gene 129
chr6_-_141946791 0.74 ENSMUST00000168119.1
Slco1a1
solute carrier organic anion transporter family, member 1a1
chr5_+_92387846 0.72 ENSMUST00000138687.1
ENSMUST00000124509.1
Art3
ADP-ribosyltransferase 3
chr19_+_39992424 0.71 ENSMUST00000049178.2
Cyp2c37
cytochrome P450, family 2. subfamily c, polypeptide 37
chr8_-_13254154 0.63 ENSMUST00000033825.4
Adprhl1
ADP-ribosylhydrolase like 1
chr15_-_13173607 0.51 ENSMUST00000036439.4
Cdh6
cadherin 6
chr18_+_23415400 0.51 ENSMUST00000115832.2
ENSMUST00000047954.7
Dtna
dystrobrevin alpha
chr5_+_92387673 0.48 ENSMUST00000145072.1
Art3
ADP-ribosyltransferase 3
chr4_+_43631935 0.45 ENSMUST00000030191.8
Npr2
natriuretic peptide receptor 2
chr1_+_191036812 0.45 ENSMUST00000077889.6
1700022P22Rik
RIKEN cDNA 1700022P22 gene
chr3_-_95882193 0.45 ENSMUST00000159863.1
ENSMUST00000159739.1
ENSMUST00000036418.3
Gm129
predicted gene 129
chr3_+_34649987 0.43 ENSMUST00000099151.2
Sox2
SRY-box containing gene 2
chr8_-_13254068 0.43 ENSMUST00000168498.1
Adprhl1
ADP-ribosylhydrolase like 1
chr7_-_89633124 0.40 ENSMUST00000172178.1
A230065N10Rik
RIKEN cDNA A230065N10 gene
chr11_-_110251736 0.38 ENSMUST00000044003.7
Abca6
ATP-binding cassette, sub-family A (ABC1), member 6
chr3_-_95882232 0.37 ENSMUST00000161866.1
Gm129
predicted gene 129
chr16_+_56477838 0.35 ENSMUST00000048471.7
ENSMUST00000096013.3
ENSMUST00000096012.3
ENSMUST00000171000.1
Abi3bp
ABI gene family, member 3 (NESH) binding protein
chr12_+_8012359 0.34 ENSMUST00000171239.1
Apob
apolipoprotein B
chr3_-_19264959 0.32 ENSMUST00000121951.1
Pde7a
phosphodiesterase 7A
chr10_-_109010955 0.32 ENSMUST00000105276.1
ENSMUST00000064054.7
Syt1
synaptotagmin I
chr8_-_13254096 0.30 ENSMUST00000171619.1
Adprhl1
ADP-ribosylhydrolase like 1
chr7_-_126676428 0.29 ENSMUST00000106373.1
Sult1a1
sulfotransferase family 1A, phenol-preferring, member 1
chr4_+_43632185 0.29 ENSMUST00000107874.2
Npr2
natriuretic peptide receptor 2
chr4_+_105157339 0.28 ENSMUST00000064139.7
Ppap2b
phosphatidic acid phosphatase type 2B
chrX_+_133850980 0.27 ENSMUST00000033602.8
Tnmd
tenomodulin
chr12_+_71111418 0.26 ENSMUST00000021482.4
Tomm20l
translocase of outer mitochondrial membrane 20 homolog (yeast)-like
chr15_+_37233036 0.24 ENSMUST00000161405.1
ENSMUST00000022895.8
ENSMUST00000161532.1
Grhl2
grainyhead-like 2 (Drosophila)
chr6_-_126698192 0.21 ENSMUST00000060972.3
Kcna5
potassium voltage-gated channel, shaker-related subfamily, member 5
chr1_-_170927567 0.21 ENSMUST00000046322.7
ENSMUST00000159171.1
Fcrla
Fc receptor-like A
chr9_+_112227443 0.20 ENSMUST00000161216.1
2310075C17Rik
RIKEN cDNA 2310075C17 gene
chr12_+_108792946 0.20 ENSMUST00000021692.7
Yy1
YY1 transcription factor
chr12_+_105604091 0.19 ENSMUST00000041229.4
Bdkrb1
bradykinin receptor, beta 1
chr7_+_107567445 0.19 ENSMUST00000120990.1
Olfml1
olfactomedin-like 1
chr2_-_60553303 0.18 ENSMUST00000112525.2
ENSMUST00000067708.5
Pla2r1
phospholipase A2 receptor 1
chr9_+_7347374 0.18 ENSMUST00000065079.5
ENSMUST00000005950.5
Mmp12
matrix metallopeptidase 12
chr2_-_110761564 0.17 ENSMUST00000140777.1
Ano3
anoctamin 3
chr17_-_46144156 0.16 ENSMUST00000024762.2
Rsph9
radial spoke head 9 homolog (Chlamydomonas)
chr16_-_32797413 0.16 ENSMUST00000115116.1
ENSMUST00000041123.8
Muc20
mucin 20
chr10_+_94576254 0.16 ENSMUST00000117929.1
Tmcc3
transmembrane and coiled coil domains 3
chr1_+_88227005 0.13 ENSMUST00000061013.6
ENSMUST00000113130.1
Mroh2a
maestro heat-like repeat family member 2A
chr18_+_39773497 0.12 ENSMUST00000063219.2
Pabpc2
poly(A) binding protein, cytoplasmic 2
chr2_+_105092018 0.12 ENSMUST00000111107.1
Gm11060
predicted gene 11060
chr6_+_133105239 0.11 ENSMUST00000100864.4
2700089E24Rik
RIKEN cDNA 2700089E24 gene
chr11_-_3193388 0.11 ENSMUST00000081318.6
ENSMUST00000142315.1
ENSMUST00000118627.1
ENSMUST00000066391.7
Sfi1
Sfi1 homolog, spindle assembly associated (yeast)
chr6_+_120666388 0.11 ENSMUST00000112686.1
Cecr2
cat eye syndrome chromosome region, candidate 2
chr9_-_106789130 0.11 ENSMUST00000046502.5
Rad54l2
RAD54 like 2 (S. cerevisiae)
chr3_+_51559757 0.10 ENSMUST00000180616.1
5031434O11Rik
RIKEN cDNA 5031434O11 gene
chr16_+_32431225 0.10 ENSMUST00000115140.1
Pcyt1a
phosphate cytidylyltransferase 1, choline, alpha isoform
chr18_+_37442517 0.10 ENSMUST00000056915.1
Pcdhb13
protocadherin beta 13
chr1_-_172895048 0.10 ENSMUST00000027824.5
Apcs
serum amyloid P-component
chr1_-_173599074 0.09 ENSMUST00000150649.1
ENSMUST00000180215.1
ENSMUST00000097462.2
Pydc4
pyrin domain containing 4
chr2_-_84678051 0.09 ENSMUST00000053664.8
ENSMUST00000111664.1
Tmx2
thioredoxin-related transmembrane protein 2
chr8_+_34115030 0.09 ENSMUST00000095345.3
Mboat4
membrane bound O-acyltransferase domain containing 4
chr19_-_44029201 0.08 ENSMUST00000026211.8
Cyp2c44
cytochrome P450, family 2, subfamily c, polypeptide 44
chr7_-_67645195 0.08 ENSMUST00000032775.5
ENSMUST00000053950.2
Lrrc28
leucine rich repeat containing 28
chr18_-_25753852 0.08 ENSMUST00000025117.6
ENSMUST00000115816.2
Celf4
CUGBP, Elav-like family member 4
chr2_+_122637844 0.08 ENSMUST00000047498.8
AA467197
expressed sequence AA467197
chr17_+_71019503 0.08 ENSMUST00000024847.7
Myom1
myomesin 1
chr8_+_104831572 0.07 ENSMUST00000059449.6
Ces2b
carboxyesterase 2B
chr9_+_122117338 0.07 ENSMUST00000120173.1
ENSMUST00000134949.1
ENSMUST00000119215.1
Snrk
SNF related kinase
chrX_+_82948861 0.07 ENSMUST00000114000.1
Dmd
dystrophin, muscular dystrophy
chr1_+_87594545 0.07 ENSMUST00000165109.1
ENSMUST00000070898.5
Neu2
neuraminidase 2
chr13_-_98694768 0.06 ENSMUST00000148950.1
Tmem171
transmembrane protein 171
chr7_+_34095431 0.06 ENSMUST00000108083.1
ENSMUST00000174820.1
Scgb1b30
secretoglobin, family 1B, member 30
chr17_+_71019548 0.06 ENSMUST00000073211.5
ENSMUST00000179759.1
Myom1
myomesin 1
chr18_+_62662108 0.06 ENSMUST00000163259.1
Gm17732
predicted gene, 17732
chr10_-_100307185 0.05 ENSMUST00000179109.1
Gm9476
predicted gene 9476
chrX_+_47912387 0.05 ENSMUST00000001202.8
ENSMUST00000115020.1
Ocrl
oculocerebrorenal syndrome of Lowe
chr8_-_79399513 0.05 ENSMUST00000066091.7
ENSMUST00000109885.1
ENSMUST00000066081.3
Smad1
SMAD family member 1
chr4_+_122836236 0.04 ENSMUST00000030412.4
ENSMUST00000121870.1
ENSMUST00000097902.4
Ppt1
palmitoyl-protein thioesterase 1
chr6_+_97210689 0.04 ENSMUST00000044681.6
Arl6ip5
ADP-ribosylation factor-like 6 interacting protein 5
chr1_-_31222644 0.04 ENSMUST00000135245.1
4931428L18Rik
RIKEN cDNA 4931428L18 gene
chr1_+_180330470 0.04 ENSMUST00000070181.6
Itpkb
inositol 1,4,5-trisphosphate 3-kinase B
chr11_-_109298090 0.04 ENSMUST00000106704.2
Rgs9
regulator of G-protein signaling 9
chr11_-_32267547 0.04 ENSMUST00000109389.2
ENSMUST00000129010.1
ENSMUST00000020530.5
Nprl3
nitrogen permease regulator-like 3
chr8_-_11008458 0.03 ENSMUST00000040514.6
Irs2
insulin receptor substrate 2
chr11_-_99285260 0.03 ENSMUST00000017255.3
Krt24
keratin 24
chr2_+_84678396 0.03 ENSMUST00000102645.3
Med19
mediator of RNA polymerase II transcription, subunit 19 homolog (yeast)
chr12_+_110601439 0.02 ENSMUST00000018851.7
Dync1h1
dynein cytoplasmic 1 heavy chain 1
chr14_-_23650189 0.02 ENSMUST00000112423.3
Kcnma1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr17_-_51810866 0.02 ENSMUST00000176669.1
Satb1
special AT-rich sequence binding protein 1
chr13_+_23162643 0.02 ENSMUST00000076180.1
Vmn1r219
vomeronasal 1 receptor 219
chr13_-_21612004 0.02 ENSMUST00000051874.2
Olfr1362
olfactory receptor 1362
chr4_+_43493345 0.01 ENSMUST00000030181.5
ENSMUST00000107922.2
Ccdc107
coiled-coil domain containing 107
chr10_-_130127055 0.01 ENSMUST00000074161.1
Olfr824
olfactory receptor 824
chr19_+_22692613 0.01 ENSMUST00000099564.2
ENSMUST00000099566.3
Trpm3
transient receptor potential cation channel, subfamily M, member 3
chr9_+_87729285 0.01 ENSMUST00000181359.1
D030062O11Rik
RIKEN cDNA D030062O11 gene
chr5_-_131538687 0.01 ENSMUST00000161374.1
Auts2
autism susceptibility candidate 2
chr5_+_31297551 0.00 ENSMUST00000072228.5
Gckr
glucokinase regulatory protein
chr6_+_106118924 0.00 ENSMUST00000079416.5
Cntn4
contactin 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Arid5b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.2 1.4 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.4 GO:0050973 detection of mechanical stimulus involved in equilibrioception(GO:0050973)
0.1 2.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.2 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.7 GO:1900194 receptor guanylyl cyclase signaling pathway(GO:0007168) negative regulation of oocyte maturation(GO:1900194)
0.1 0.2 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.1 1.6 GO:0035634 response to stilbenoid(GO:0035634)
0.1 0.3 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.0 0.3 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.2 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0052422 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.2 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.2 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.8 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.2 GO:0061591 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 1.0 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 3.1 GO:0007586 digestion(GO:0007586)
0.0 0.3 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.0 0.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.0 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.0 0.2 GO:0060294 cilium movement involved in cell motility(GO:0060294)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0046691 intracellular canaliculus(GO:0046691)
0.0 0.3 GO:0034363 vesicle lumen(GO:0031983) intermediate-density lipoprotein particle(GO:0034363)
0.0 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0090537 CERF complex(GO:0090537)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.6 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.6 GO:0004556 alpha-amylase activity(GO:0004556)
0.3 1.4 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.3 1.3 GO:0051373 FATZ binding(GO:0051373)
0.1 0.7 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.3 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.1 1.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.2 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1 0.2 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 2.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 1.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.3 GO:0035473 lipase binding(GO:0035473)
0.0 0.7 GO:0070330 aromatase activity(GO:0070330)
0.0 0.4 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 3.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 1.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport