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GSE58827: Dynamics of the Mouse Liver

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Results for Atf5

Z-value: 0.58

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Transcription factors associated with Atf5

Gene Symbol Gene ID Gene Info
Atf5
ENSMUSG00000038539.8 activating transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Atf5mm10_v2_chr7_-_44815658_44815682-0.115.2e-01Click!

Activity profile of Atf5 motif

Sorted Z-values of Atf5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_41314700 2.57 ENSMUST00000064324.5
Try5
trypsin 5
chr14_+_54936456 0.90 ENSMUST00000037814.6
Cmtm5
CKLF-like MARVEL transmembrane domain containing 5
chr3_-_18243289 0.65 ENSMUST00000035625.6
Cyp7b1
cytochrome P450, family 7, subfamily b, polypeptide 1
chr1_-_153851189 0.64 ENSMUST00000059607.6
5830403L16Rik
RIKEN cDNA 5830403L16 gene
chr4_+_21727695 0.63 ENSMUST00000065928.4
Ccnc
cyclin C
chr10_+_115384951 0.60 ENSMUST00000036044.8
Zfc3h1
zinc finger, C3H1-type containing
chrX_+_42150672 0.59 ENSMUST00000069619.7
Stag2
stromal antigen 2
chr11_-_20112876 0.58 ENSMUST00000000137.7
Actr2
ARP2 actin-related protein 2
chrX_+_42151002 0.57 ENSMUST00000123245.1
Stag2
stromal antigen 2
chr15_+_12117848 0.57 ENSMUST00000128475.1
ENSMUST00000134277.1
Zfr
zinc finger RNA binding protein
chr12_-_56535047 0.56 ENSMUST00000178477.2
Nkx2-1
NK2 homeobox 1
chr4_+_21727726 0.53 ENSMUST00000102997.1
ENSMUST00000120679.1
ENSMUST00000108240.2
Ccnc
cyclin C
chr18_+_44334062 0.52 ENSMUST00000025349.5
ENSMUST00000115498.1
Myot
myotilin
chrX_+_166344692 0.49 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
Gpm6b
glycoprotein m6b
chr6_-_40585783 0.47 ENSMUST00000177178.1
ENSMUST00000129948.2
ENSMUST00000101491.4
Clec5a
C-type lectin domain family 5, member a
chr4_+_86748526 0.45 ENSMUST00000082026.7
ENSMUST00000045512.8
Dennd4c
DENN/MADD domain containing 4C
chr17_-_46031813 0.44 ENSMUST00000024747.7
Vegfa
vascular endothelial growth factor A
chr15_-_103252810 0.42 ENSMUST00000154510.1
Nfe2
nuclear factor, erythroid derived 2
chrX_+_38772671 0.41 ENSMUST00000050744.5
6030498E09Rik
RIKEN cDNA 6030498E09 gene
chr4_-_11322109 0.41 ENSMUST00000084892.5
ENSMUST00000128024.1
Dpy19l4
dpy-19-like 4 (C. elegans)
chr4_+_63215402 0.40 ENSMUST00000036300.6
Col27a1
collagen, type XXVII, alpha 1
chr19_-_42202150 0.39 ENSMUST00000018966.7
Sfrp5
secreted frizzled-related sequence protein 5
chr1_-_174250976 0.38 ENSMUST00000061990.4
Olfr419
olfactory receptor 419
chr15_+_41830921 0.38 ENSMUST00000166917.1
Oxr1
oxidation resistance 1
chr9_+_54980880 0.37 ENSMUST00000093844.3
Chrna5
cholinergic receptor, nicotinic, alpha polypeptide 5
chr5_+_32611171 0.37 ENSMUST00000072311.6
ENSMUST00000168707.2
Yes1
Yamaguchi sarcoma viral (v-yes) oncogene homolog 1
chr19_-_4698315 0.37 ENSMUST00000096325.3
Gm960
predicted gene 960
chr16_-_16560201 0.37 ENSMUST00000162045.1
ENSMUST00000162124.1
ENSMUST00000161861.1
Fgd4
FYVE, RhoGEF and PH domain containing 4
chr11_+_49523721 0.37 ENSMUST00000077143.4
Olfr1383
olfactory receptor 1383
chr3_+_103914099 0.37 ENSMUST00000051139.6
ENSMUST00000068879.4
Rsbn1
rosbin, round spermatid basic protein 1
chr6_-_97205549 0.36 ENSMUST00000164744.1
ENSMUST00000089287.5
Uba3
ubiquitin-like modifier activating enzyme 3
chr10_+_95940663 0.36 ENSMUST00000053484.6
Eea1
early endosome antigen 1
chr18_+_65582281 0.36 ENSMUST00000183319.1
Zfp532
zinc finger protein 532
chr3_-_94436574 0.35 ENSMUST00000029787.4
Oaz3
ornithine decarboxylase antizyme 3
chr16_-_16560046 0.35 ENSMUST00000172181.2
Fgd4
FYVE, RhoGEF and PH domain containing 4
chrX_-_41911877 0.35 ENSMUST00000047037.8
Thoc2
THO complex 2
chr19_-_29805989 0.34 ENSMUST00000177155.1
ENSMUST00000059484.7
9930021J03Rik
RIKEN cDNA 9930021J03 gene
chr11_-_83302586 0.33 ENSMUST00000176374.1
Pex12
peroxisomal biogenesis factor 12
chr18_+_35562158 0.31 ENSMUST00000166793.1
Matr3
matrin 3
chr7_+_128062698 0.30 ENSMUST00000119696.1
Itgam
integrin alpha M
chr4_+_11758147 0.30 ENSMUST00000029871.5
ENSMUST00000108303.1
Cdh17
cadherin 17
chr16_+_38089001 0.29 ENSMUST00000023507.6
Gsk3b
glycogen synthase kinase 3 beta
chr1_-_64121389 0.29 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chr3_-_79737794 0.28 ENSMUST00000078527.6
Rxfp1
relaxin/insulin-like family peptide receptor 1
chr1_-_37536232 0.26 ENSMUST00000042161.8
Mgat4a
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr7_+_128062657 0.25 ENSMUST00000120355.1
ENSMUST00000106240.2
ENSMUST00000098015.3
Itgam
integrin alpha M
chr1_-_53785214 0.25 ENSMUST00000027263.7
Stk17b
serine/threonine kinase 17b (apoptosis-inducing)
chr16_+_17898617 0.25 ENSMUST00000055374.6
Tssk2
testis-specific serine kinase 2
chr1_-_135167606 0.25 ENSMUST00000027682.8
Gpr37l1
G protein-coupled receptor 37-like 1
chr16_-_46010212 0.24 ENSMUST00000130481.1
Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr11_+_83302817 0.24 ENSMUST00000142680.1
Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr18_+_64254359 0.24 ENSMUST00000025477.7
St8sia3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr2_-_120539852 0.24 ENSMUST00000171215.1
Zfp106
zinc finger protein 106
chr9_-_57606234 0.22 ENSMUST00000045068.8
Cplx3
complexin 3
chr7_-_4725082 0.21 ENSMUST00000086363.4
ENSMUST00000086364.4
Tmem150b
transmembrane protein 150B
chr1_-_175692624 0.20 ENSMUST00000027809.7
Opn3
opsin 3
chr3_-_30509462 0.20 ENSMUST00000173899.1
Mecom
MDS1 and EVI1 complex locus
chr1_-_163313661 0.19 ENSMUST00000174397.1
ENSMUST00000075805.6
ENSMUST00000027878.7
Prrx1
paired related homeobox 1
chrX_-_17572241 0.18 ENSMUST00000176638.1
ENSMUST00000026016.6
Fundc1
FUN14 domain containing 1
chr7_-_26394238 0.18 ENSMUST00000041845.7
ENSMUST00000085944.5
Nlrp9c
NLR family, pyrin domain containing 9C
chr8_+_54954728 0.18 ENSMUST00000033915.7
Gpm6a
glycoprotein m6a
chr15_-_78206391 0.18 ENSMUST00000120592.1
Pvalb
parvalbumin
chr2_+_172393794 0.17 ENSMUST00000099061.2
ENSMUST00000103073.2
Cass4
Cas scaffolding protein family member 4
chr1_-_65179058 0.17 ENSMUST00000097709.4
Idh1
isocitrate dehydrogenase 1 (NADP+), soluble
chr4_-_43046196 0.17 ENSMUST00000036462.5
Fam214b
family with sequence similarity 214, member B
chr11_+_70505244 0.17 ENSMUST00000019063.2
Tm4sf5
transmembrane 4 superfamily member 5
chr2_+_10047838 0.17 ENSMUST00000181588.1
C630004M23Rik
RIKEN cDNA C630004M23 gene
chr10_+_108332173 0.17 ENSMUST00000095313.3
Pawr
PRKC, apoptosis, WT1, regulator
chr10_-_63244135 0.16 ENSMUST00000054837.3
1700120B22Rik
RIKEN cDNA 1700120B22 gene
chr6_-_144209448 0.16 ENSMUST00000077160.5
Sox5
SRY-box containing gene 5
chr7_+_29134971 0.15 ENSMUST00000160194.1
Rasgrp4
RAS guanyl releasing protein 4
chr14_+_12284198 0.15 ENSMUST00000112669.3
ENSMUST00000163392.1
3830406C13Rik
RIKEN cDNA 3830406C13 gene
chr6_+_33249085 0.15 ENSMUST00000052266.8
ENSMUST00000090381.4
ENSMUST00000115080.1
Exoc4
exocyst complex component 4
chr7_+_24370255 0.14 ENSMUST00000171904.1
Kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr2_+_10372426 0.14 ENSMUST00000114864.2
ENSMUST00000116594.2
ENSMUST00000041105.6
Sfmbt2
Scm-like with four mbt domains 2
chr11_-_46166397 0.14 ENSMUST00000020679.2
Nipal4
NIPA-like domain containing 4
chrX_-_17571563 0.14 ENSMUST00000177213.1
Fundc1
FUN14 domain containing 1
chr3_+_99253754 0.14 ENSMUST00000029462.5
Tbx15
T-box 15
chr11_+_4236411 0.13 ENSMUST00000075221.2
Osm
oncostatin M
chr1_-_152902628 0.13 ENSMUST00000111836.2
ENSMUST00000073441.6
Smg7
Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr13_+_104287855 0.12 ENSMUST00000065766.6
Adamts6
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6
chr11_-_120630126 0.12 ENSMUST00000106180.1
Mafg
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr11_-_95842409 0.12 ENSMUST00000059026.3
Abi3
ABI gene family, member 3
chr15_-_34356421 0.12 ENSMUST00000179647.1
9430069I07Rik
RIKEN cDNA 9430069I07 gene
chr6_+_65590382 0.12 ENSMUST00000114236.1
Tnip3
TNFAIP3 interacting protein 3
chr12_+_3365108 0.12 ENSMUST00000020999.5
Kif3c
kinesin family member 3C
chr6_-_137571007 0.11 ENSMUST00000100841.2
Eps8
epidermal growth factor receptor pathway substrate 8
chr4_-_82705735 0.11 ENSMUST00000155821.1
Nfib
nuclear factor I/B
chr4_+_11579647 0.10 ENSMUST00000180239.1
Fsbp
fibrinogen silencer binding protein
chr2_+_162987330 0.10 ENSMUST00000018012.7
Sgk2
serum/glucocorticoid regulated kinase 2
chr3_+_114030532 0.10 ENSMUST00000123619.1
ENSMUST00000092155.5
Col11a1
collagen, type XI, alpha 1
chr10_-_14544972 0.10 ENSMUST00000041168.4
Gpr126
G protein-coupled receptor 126
chr4_+_54947976 0.10 ENSMUST00000098070.3
Zfp462
zinc finger protein 462
chr8_-_95807458 0.09 ENSMUST00000098473.4
ENSMUST00000068452.8
Cnot1
CCR4-NOT transcription complex, subunit 1
chr10_-_14718191 0.09 ENSMUST00000020016.4
Gje1
gap junction protein, epsilon 1
chr1_+_97024681 0.09 ENSMUST00000054664.7
Gm6430
predicted gene 6430
chr5_-_86373413 0.09 ENSMUST00000031175.5
Tmprss11d
transmembrane protease, serine 11d
chr7_+_126584937 0.09 ENSMUST00000039522.6
Apobr
apolipoprotein B receptor
chr6_-_127769427 0.08 ENSMUST00000032500.8
Prmt8
protein arginine N-methyltransferase 8
chr10_+_63243785 0.08 ENSMUST00000020258.8
Herc4
hect domain and RLD 4
chr16_+_30065333 0.08 ENSMUST00000023171.7
Hes1
hairy and enhancer of split 1 (Drosophila)
chr7_-_19887946 0.08 ENSMUST00000052605.7
Ceacam19
carcinoembryonic antigen-related cell adhesion molecule 19
chr1_-_64121456 0.07 ENSMUST00000142009.1
ENSMUST00000114086.1
Klf7
Kruppel-like factor 7 (ubiquitous)
chr19_-_37178011 0.07 ENSMUST00000133988.1
Cpeb3
cytoplasmic polyadenylation element binding protein 3
chr18_+_61953048 0.07 ENSMUST00000051720.5
Sh3tc2
SH3 domain and tetratricopeptide repeats 2
chr4_+_11321930 0.06 ENSMUST00000181105.1
Gm26663
predicted gene, 26663
chr11_+_53433299 0.06 ENSMUST00000018382.6
Gdf9
growth differentiation factor 9
chr18_+_65581704 0.06 ENSMUST00000182979.1
Zfp532
zinc finger protein 532
chr8_+_57332111 0.05 ENSMUST00000181638.1
5033428I22Rik
RIKEN cDNA 5033428I22 gene
chr1_-_56971762 0.05 ENSMUST00000114415.3
Satb2
special AT-rich sequence binding protein 2
chr15_-_79164477 0.05 ENSMUST00000040019.4
Sox10
SRY-box containing gene 10
chr10_-_53699343 0.05 ENSMUST00000163761.1
Fam184a
family with sequence similarity 184, member A
chr11_-_69369377 0.05 ENSMUST00000092971.6
ENSMUST00000108661.1
Chd3
chromodomain helicase DNA binding protein 3
chr13_-_98206151 0.05 ENSMUST00000109426.1
Arhgef28
Rho guanine nucleotide exchange factor (GEF) 28
chrX_+_41401304 0.05 ENSMUST00000076349.5
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr7_+_29134854 0.04 ENSMUST00000161522.1
ENSMUST00000159975.1
ENSMUST00000032811.5
ENSMUST00000094617.4
Rasgrp4
RAS guanyl releasing protein 4
chr6_+_67266979 0.04 ENSMUST00000042990.4
Serbp1
serpine1 mRNA binding protein 1
chr18_-_11051479 0.04 ENSMUST00000180789.1
1010001N08Rik
RIKEN cDNA 1010001N08 gene
chr5_+_119671011 0.04 ENSMUST00000018748.8
Tbx3
T-box 3
chr2_+_172393900 0.04 ENSMUST00000109136.2
Cass4
Cas scaffolding protein family member 4
chr3_-_92458715 0.04 ENSMUST00000058142.3
Sprr3
small proline-rich protein 3
chr4_-_8239034 0.04 ENSMUST00000066674.7
Car8
carbonic anhydrase 8
chr9_+_32116040 0.04 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chr8_+_81773105 0.03 ENSMUST00000170160.1
Inpp4b
inositol polyphosphate-4-phosphatase, type II
chr9_+_78113275 0.03 ENSMUST00000009972.5
ENSMUST00000117330.1
ENSMUST00000044551.7
Ick
intestinal cell kinase
chr2_-_153444441 0.03 ENSMUST00000109784.1
8430427H17Rik
RIKEN cDNA 8430427H17 gene
chr10_-_20725023 0.03 ENSMUST00000020165.7
Pde7b
phosphodiesterase 7B
chr1_+_153665627 0.03 ENSMUST00000147482.1
Rgs8
regulator of G-protein signaling 8
chr17_+_35220834 0.03 ENSMUST00000118793.1
Gm16181
predicted gene 16181
chr18_+_65582239 0.03 ENSMUST00000182684.1
Zfp532
zinc finger protein 532
chr9_+_40187079 0.02 ENSMUST00000062229.5
Olfr986
olfactory receptor 986
chr14_-_101609033 0.02 ENSMUST00000161991.1
ENSMUST00000100340.3
Tbc1d4
TBC1 domain family, member 4
chr5_+_119670825 0.02 ENSMUST00000121021.1
Tbx3
T-box 3
chr13_-_116309639 0.02 ENSMUST00000036060.6
Isl1
ISL1 transcription factor, LIM/homeodomain
chr1_+_188953744 0.02 ENSMUST00000127077.1
Ush2a
Usher syndrome 2A (autosomal recessive, mild)
chr6_+_88222268 0.02 ENSMUST00000061866.4
Dnajb8
DnaJ (Hsp40) homolog, subfamily B, member 8
chr7_-_4164442 0.01 ENSMUST00000140410.1
ENSMUST00000143825.1
Cdc42ep5
CDC42 effector protein (Rho GTPase binding) 5
chr5_-_86197846 0.01 ENSMUST00000094654.2
Gnrhr
gonadotropin releasing hormone receptor
chr5_-_147307264 0.01 ENSMUST00000031650.3
Cdx2
caudal type homeobox 2
chr14_-_12823031 0.01 ENSMUST00000067491.6
ENSMUST00000177814.1
ENSMUST00000112658.1
ENSMUST00000112657.2
Cadps
Ca2+-dependent secretion activator
chr11_+_83302641 0.01 ENSMUST00000176430.1
ENSMUST00000065692.7
Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr10_-_20724696 0.00 ENSMUST00000170265.1
Pde7b
phosphodiesterase 7B
chr14_-_20668269 0.00 ENSMUST00000057090.5
ENSMUST00000117386.1
Synpo2l
synaptopodin 2-like
chr1_+_153665587 0.00 ENSMUST00000147700.1
Rgs8
regulator of G-protein signaling 8

Network of associatons between targets according to the STRING database.

First level regulatory network of Atf5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.2 0.6 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.4 GO:0038190 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190)
0.1 0.4 GO:2000041 regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.1 1.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 1.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.4 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.3 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.3 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1 0.3 GO:0060618 nipple development(GO:0060618)
0.1 0.4 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 0.4 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.7 GO:0030035 microspike assembly(GO:0030035)
0.1 0.6 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.1 0.1 GO:0045608 negative regulation of auditory receptor cell differentiation(GO:0045608)
0.1 0.4 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 0.6 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 0.4 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 0.5 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.1 0.2 GO:1990743 protein sialylation(GO:1990743)
0.1 0.2 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.2 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.0 0.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.4 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.0 0.3 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 1.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:0035989 tendon development(GO:0035989)
0.0 0.5 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0 0.1 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.4 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 2.7 GO:0007586 digestion(GO:0007586)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.3 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.2 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.0 0.4 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.1 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.0 0.1 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 0.1 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.2 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.2 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 0.6 GO:0030478 actin cap(GO:0030478)
0.1 0.4 GO:0044308 axonal spine(GO:0044308)
0.0 0.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 1.2 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.3 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.6 GO:0008305 integrin complex(GO:0008305)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.3 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.4 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.6 GO:0001851 complement component C3b binding(GO:0001851)
0.1 0.4 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.2 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 0.6 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 1.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.4 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.1 GO:0071820 N-box binding(GO:0071820)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.4 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.5 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 2.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.5 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.6 GO:0008395 steroid hydroxylase activity(GO:0008395)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.2 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.3 PID CDC42 PATHWAY CDC42 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.2 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.1 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex