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GSE58827: Dynamics of the Mouse Liver
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Results for Bbx
Z-value: 0.31
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Transcription factors associated with Bbx
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Bbx | mm10_v2_chr16_-_50330987_50331017 | -0.22 | 1.9e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr19_-_7966000 Show fit | 1.94 |
ENSMUST00000182102.1
ENSMUST00000075619.4 |
solute carrier family 22, member 27 |
|
| chr19_-_11081088 Show fit | 1.35 |
ENSMUST00000025636.6
|
membrane-spanning 4-domains, subfamily A, member 8A |
|
| chr8_+_45658666 Show fit | 1.06 |
ENSMUST00000134675.1
ENSMUST00000139869.1 ENSMUST00000126067.1 |
sorbin and SH3 domain containing 2 |
|
| chr2_+_58754910 Show fit | 1.03 |
ENSMUST00000059102.6
|
uridine phosphorylase 2 |
|
| chr6_+_124304646 Show fit | 1.02 |
ENSMUST00000112541.2
ENSMUST00000032234.2 |
CD163 antigen |
|
| chr1_-_13660476 Show fit | 0.97 |
ENSMUST00000027071.5
|
lactamase, beta 2 |
|
| chr15_-_3303521 Show fit | 0.95 |
ENSMUST00000165386.1
|
coiled-coil domain containing 152 |
|
| chr8_+_45658273 Show fit | 0.91 |
ENSMUST00000153798.1
|
sorbin and SH3 domain containing 2 |
|
| chr7_+_51880312 Show fit | 0.77 |
ENSMUST00000145049.1
|
growth arrest specific 2 |
|
| chr5_-_108675569 Show fit | 0.70 |
ENSMUST00000051757.7
|
solute carrier family 26 (sulfate transporter), member 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Bbx
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.7 | GO:0061049 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.1 | 1.9 | GO:0015747 | urate transport(GO:0015747) |
| 0.0 | 1.0 | GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502) |
| 0.0 | 1.0 | GO:0006953 | acute-phase response(GO:0006953) |
| 0.1 | 0.7 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.1 | 0.6 | GO:0035754 | B cell chemotaxis(GO:0035754) |
| 0.1 | 0.5 | GO:0009441 | glycolate metabolic process(GO:0009441) |
| 0.0 | 0.4 | GO:0048733 | sebaceous gland development(GO:0048733) |
| 0.0 | 0.4 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
| 0.0 | 0.3 | GO:0045948 | positive regulation of translational initiation(GO:0045948) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.0 | GO:0045098 | type III intermediate filament(GO:0045098) |
| 0.0 | 0.4 | GO:0045095 | keratin filament(GO:0045095) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.9 | GO:1901702 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.2 | 1.0 | GO:0004850 | uridine phosphorylase activity(GO:0004850) |
| 0.0 | 1.0 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.0 | 1.0 | GO:0004521 | endoribonuclease activity(GO:0004521) |
| 0.0 | 0.7 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.0 | 0.6 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) |
| 0.1 | 0.5 | GO:0016899 | oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899) |
| 0.0 | 0.3 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.0 | 0.3 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.0 | 0.1 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.0 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |
| 0.0 | 0.8 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.0 | 0.6 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 0.0 | 0.3 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |