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GSE58827: Dynamics of the Mouse Liver

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Results for E2f2_E2f5

Z-value: 5.21

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Transcription factors associated with E2f2_E2f5

Gene Symbol Gene ID Gene Info
E2f2
ENSMUSG00000018983.9 E2F transcription factor 2
E2f5
ENSMUSG00000027552.8 E2F transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2f2mm10_v2_chr4_+_136172367_1361723950.961.0e-20Click!
E2f5mm10_v2_chr3_+_14578609_145786870.464.3e-03Click!

Activity profile of E2f2_E2f5 motif

Sorted Z-values of E2f2_E2f5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_136172367 80.62 ENSMUST00000061721.5
E2f2
E2F transcription factor 2
chr4_+_134864536 75.27 ENSMUST00000030627.7
Rhd
Rh blood group, D antigen
chr4_+_126556935 54.09 ENSMUST00000048391.8
Clspn
claspin
chr17_+_56304313 46.71 ENSMUST00000113035.1
ENSMUST00000113039.2
ENSMUST00000142387.1
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr4_+_126556994 45.17 ENSMUST00000147675.1
Clspn
claspin
chr15_-_55090422 44.94 ENSMUST00000110231.1
ENSMUST00000023059.6
Dscc1
defective in sister chromatid cohesion 1 homolog (S. cerevisiae)
chr12_+_24708241 40.94 ENSMUST00000020980.5
Rrm2
ribonucleotide reductase M2
chr7_-_6730412 40.20 ENSMUST00000051209.4
Peg3
paternally expressed 3
chr9_+_122951051 38.28 ENSMUST00000040717.5
Kif15
kinesin family member 15
chr10_-_69352886 36.79 ENSMUST00000119827.1
ENSMUST00000020099.5
Cdk1
cyclin-dependent kinase 1
chr8_+_75109528 36.73 ENSMUST00000164309.1
Mcm5
minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)
chr13_-_55329723 36.57 ENSMUST00000021941.7
Mxd3
Max dimerization protein 3
chr10_-_5805412 36.07 ENSMUST00000019907.7
Fbxo5
F-box protein 5
chr6_+_4747306 35.57 ENSMUST00000175823.1
ENSMUST00000176204.1
ENSMUST00000166678.1
Peg10
paternally expressed 10
chr2_-_28621932 34.12 ENSMUST00000028156.7
ENSMUST00000164290.1
Gfi1b
growth factor independent 1B
chr15_-_58135047 31.85 ENSMUST00000038194.3
Atad2
ATPase family, AAA domain containing 2
chr6_-_88898664 31.71 ENSMUST00000058011.6
Mcm2
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chr5_-_138171813 30.97 ENSMUST00000155902.1
ENSMUST00000148879.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chrX_-_51205990 30.53 ENSMUST00000114876.2
Mbnl3
muscleblind-like 3 (Drosophila)
chrX_-_51205773 30.11 ENSMUST00000114875.1
Mbnl3
muscleblind-like 3 (Drosophila)
chr11_+_80089385 28.56 ENSMUST00000108239.1
ENSMUST00000017694.5
Atad5
ATPase family, AAA domain containing 5
chr10_-_21160925 27.75 ENSMUST00000020158.6
Myb
myeloblastosis oncogene
chr12_-_69228167 26.85 ENSMUST00000021359.5
Pole2
polymerase (DNA directed), epsilon 2 (p59 subunit)
chr1_-_128359610 26.47 ENSMUST00000027601.4
Mcm6
minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)
chr4_+_115000156 26.40 ENSMUST00000030490.6
Stil
Scl/Tal1 interrupting locus
chr2_+_72476159 26.37 ENSMUST00000102691.4
Cdca7
cell division cycle associated 7
chr4_+_115000174 26.19 ENSMUST00000129957.1
Stil
Scl/Tal1 interrupting locus
chr9_-_20952838 24.86 ENSMUST00000004202.9
Dnmt1
DNA methyltransferase (cytosine-5) 1
chr12_-_11265768 24.21 ENSMUST00000166117.1
Gen1
Gen homolog 1, endonuclease (Drosophila)
chr2_+_72476225 23.98 ENSMUST00000157019.1
Cdca7
cell division cycle associated 7
chr2_-_113848655 22.87 ENSMUST00000102545.1
ENSMUST00000110948.1
Arhgap11a
Rho GTPase activating protein 11A
chr17_+_56303396 22.85 ENSMUST00000113038.1
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr1_-_20820213 22.79 ENSMUST00000053266.9
Mcm3
minichromosome maintenance deficient 3 (S. cerevisiae)
chr9_+_109875541 22.18 ENSMUST00000094324.3
Cdc25a
cell division cycle 25A
chr1_-_191575534 21.95 ENSMUST00000027933.5
Dtl
denticleless homolog (Drosophila)
chr5_-_138172383 21.21 ENSMUST00000000505.9
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr2_-_113848601 21.18 ENSMUST00000110949.2
Arhgap11a
Rho GTPase activating protein 11A
chr2_-_157204483 21.00 ENSMUST00000029170.7
Rbl1
retinoblastoma-like 1 (p107)
chr12_+_116405397 20.78 ENSMUST00000084828.3
Ncapg2
non-SMC condensin II complex, subunit G2
chr2_+_119112793 20.50 ENSMUST00000140939.1
ENSMUST00000028795.3
Rad51
RAD51 homolog
chr12_+_24708984 19.66 ENSMUST00000154588.1
Rrm2
ribonucleotide reductase M2
chr2_-_154569845 19.15 ENSMUST00000103145.4
E2f1
E2F transcription factor 1
chr15_+_102296256 19.09 ENSMUST00000064924.4
Espl1
extra spindle poles-like 1 (S. cerevisiae)
chr15_-_9140374 19.05 ENSMUST00000096482.3
ENSMUST00000110585.2
Skp2
S-phase kinase-associated protein 2 (p45)
chr10_+_110745433 19.03 ENSMUST00000174857.1
ENSMUST00000073781.5
ENSMUST00000173471.1
ENSMUST00000173634.1
E2f7
E2F transcription factor 7
chr11_+_116532441 18.62 ENSMUST00000106386.1
ENSMUST00000145737.1
ENSMUST00000155102.1
ENSMUST00000063446.6
Sphk1
sphingosine kinase 1
chrX_+_20703906 18.35 ENSMUST00000033383.2
Usp11
ubiquitin specific peptidase 11
chr9_+_64281575 18.01 ENSMUST00000034964.6
Tipin
timeless interacting protein
chr12_-_4874341 17.90 ENSMUST00000137337.1
ENSMUST00000045921.7
Mfsd2b
major facilitator superfamily domain containing 2B
chr11_+_116533257 17.82 ENSMUST00000154034.1
Sphk1
sphingosine kinase 1
chr13_-_22042949 17.66 ENSMUST00000091741.4
Hist1h2ag
histone cluster 1, H2ag
chr11_+_95010277 17.60 ENSMUST00000124735.1
Samd14
sterile alpha motif domain containing 14
chr13_-_24761861 17.20 ENSMUST00000006898.3
ENSMUST00000110382.2
Gmnn
geminin
chr16_-_15637277 16.78 ENSMUST00000023353.3
Mcm4
minichromosome maintenance deficient 4 homolog (S. cerevisiae)
chr9_+_44334685 16.34 ENSMUST00000052686.2
H2afx
H2A histone family, member X
chr14_-_20388822 16.02 ENSMUST00000022345.6
Dnajc9
DnaJ (Hsp40) homolog, subfamily C, member 9
chr15_-_79605084 15.83 ENSMUST00000023065.6
Dmc1
DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination
chr9_+_65890237 15.59 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr10_+_13090788 15.50 ENSMUST00000121646.1
ENSMUST00000121325.1
ENSMUST00000121766.1
Plagl1
pleiomorphic adenoma gene-like 1
chr8_-_53638945 15.34 ENSMUST00000047768.4
Neil3
nei like 3 (E. coli)
chr8_-_120589304 15.26 ENSMUST00000034278.5
Gins2
GINS complex subunit 2 (Psf2 homolog)
chr19_+_8723478 15.13 ENSMUST00000180819.1
ENSMUST00000181422.1
Snhg1
small nucleolar RNA host gene (non-protein coding) 1
chr10_-_60219260 15.08 ENSMUST00000135158.2
Chst3
carbohydrate (chondroitin 6/keratan) sulfotransferase 3
chr13_+_22043189 15.04 ENSMUST00000110452.1
Hist1h2bj
histone cluster 1, H2bj
chr6_+_113531675 14.50 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2
Fanconi anemia, complementation group D2
chr14_+_79451791 14.32 ENSMUST00000100359.1
Zbtbd6
kelch repeat and BTB (POZ) domain containing 6
chr1_-_86359455 14.17 ENSMUST00000027438.6
Ncl
nucleolin
chr7_-_44548733 14.05 ENSMUST00000145956.1
ENSMUST00000049343.8
Pold1
polymerase (DNA directed), delta 1, catalytic subunit
chr3_+_88532314 13.95 ENSMUST00000172699.1
Mex3a
mex3 homolog A (C. elegans)
chrX_-_93632113 13.55 ENSMUST00000006856.2
Pola1
polymerase (DNA directed), alpha 1
chr5_+_88764983 13.43 ENSMUST00000031311.9
Dck
deoxycytidine kinase
chr16_-_18811615 13.22 ENSMUST00000096990.3
Cdc45
cell division cycle 45
chr1_-_156474249 12.75 ENSMUST00000051396.6
Soat1
sterol O-acyltransferase 1
chr4_+_134468320 12.33 ENSMUST00000030636.4
ENSMUST00000127279.1
ENSMUST00000105867.1
Stmn1
stathmin 1
chr17_+_56303321 12.32 ENSMUST00000001258.8
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr5_+_143909964 12.14 ENSMUST00000148011.1
ENSMUST00000110709.3
Pms2
postmeiotic segregation increased 2 (S. cerevisiae)
chr4_+_11191354 12.09 ENSMUST00000170901.1
Ccne2
cyclin E2
chr1_+_175880775 11.85 ENSMUST00000039725.6
Exo1
exonuclease 1
chr11_+_98907801 11.82 ENSMUST00000092706.6
Cdc6
cell division cycle 6
chrX_-_139871637 11.47 ENSMUST00000033811.7
ENSMUST00000087401.5
Morc4
microrchidia 4
chr7_-_38107490 11.44 ENSMUST00000108023.3
Ccne1
cyclin E1
chr13_-_21753851 11.28 ENSMUST00000074752.2
Hist1h2ak
histone cluster 1, H2ak
chr13_-_24761440 11.26 ENSMUST00000176890.1
ENSMUST00000175689.1
Gmnn
geminin
chr2_+_150909565 11.13 ENSMUST00000028948.4
Gins1
GINS complex subunit 1 (Psf1 homolog)
chr4_-_133967953 11.12 ENSMUST00000102553.4
Hmgn2
high mobility group nucleosomal binding domain 2
chr17_+_25016343 11.10 ENSMUST00000024983.5
Ift140
intraflagellar transport 140
chr4_+_32615473 11.05 ENSMUST00000178925.1
ENSMUST00000029950.3
Casp8ap2
caspase 8 associated protein 2
chr2_+_103970115 10.97 ENSMUST00000111143.1
ENSMUST00000138815.1
Lmo2
LIM domain only 2
chr11_+_11686213 10.63 ENSMUST00000076700.4
ENSMUST00000048122.6
Ikzf1
IKAROS family zinc finger 1
chr17_+_23726336 10.57 ENSMUST00000024701.7
Pkmyt1
protein kinase, membrane associated tyrosine/threonine 1
chr9_-_39603635 10.57 ENSMUST00000119722.1
AW551984
expressed sequence AW551984
chr19_-_10203880 10.56 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
Fen1
flap structure specific endonuclease 1
chr7_+_13278778 10.52 ENSMUST00000098814.4
ENSMUST00000146998.1
ENSMUST00000185145.1
Lig1
ligase I, DNA, ATP-dependent
chr9_-_21291124 10.50 ENSMUST00000086374.6
Cdkn2d
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr7_+_110122299 10.42 ENSMUST00000033326.8
Wee1
WEE 1 homolog 1 (S. pombe)
chr11_+_58948890 10.30 ENSMUST00000078267.3
Hist3h2ba
histone cluster 3, H2ba
chr2_-_154569720 10.27 ENSMUST00000000894.5
E2f1
E2F transcription factor 1
chr5_-_24030297 10.25 ENSMUST00000101513.2
Fam126a
family with sequence similarity 126, member A
chr4_-_136835843 10.20 ENSMUST00000105846.2
ENSMUST00000059287.7
ENSMUST00000105845.2
Ephb2
Eph receptor B2
chrX_-_150814265 10.18 ENSMUST00000026302.6
ENSMUST00000129768.1
ENSMUST00000112699.2
Maged2
melanoma antigen, family D, 2
chr18_-_62179948 10.16 ENSMUST00000053640.3
Adrb2
adrenergic receptor, beta 2
chr13_-_21787218 10.09 ENSMUST00000091751.2
Hist1h2an
histone cluster 1, H2an
chr5_+_75574916 10.03 ENSMUST00000144270.1
ENSMUST00000005815.6
Kit
kit oncogene
chr4_-_44704006 10.00 ENSMUST00000146335.1
Pax5
paired box gene 5
chrX_-_8074720 9.98 ENSMUST00000115636.3
ENSMUST00000115638.3
Suv39h1
suppressor of variegation 3-9 homolog 1 (Drosophila)
chrX_+_50841434 9.86 ENSMUST00000114887.2
2610018G03Rik
RIKEN cDNA 2610018G03 gene
chr7_-_126396715 9.78 ENSMUST00000075671.4
Nfatc2ip
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein
chr2_+_103970221 9.75 ENSMUST00000111140.2
ENSMUST00000111139.2
Lmo2
LIM domain only 2
chrX_+_42151002 9.52 ENSMUST00000123245.1
Stag2
stromal antigen 2
chr6_-_47594967 9.51 ENSMUST00000081721.6
ENSMUST00000114618.1
ENSMUST00000114616.1
Ezh2
enhancer of zeste homolog 2 (Drosophila)
chr4_+_132768325 9.45 ENSMUST00000102561.4
Rpa2
replication protein A2
chr5_+_110286306 9.42 ENSMUST00000007296.5
ENSMUST00000112482.1
Pole
polymerase (DNA directed), epsilon
chr7_+_66109474 9.40 ENSMUST00000036372.6
Chsy1
chondroitin sulfate synthase 1
chr13_-_22035589 9.21 ENSMUST00000091742.4
Hist1h2ah
histone cluster 1, H2ah
chr15_+_82298943 9.07 ENSMUST00000023089.3
Wbp2nl
WBP2 N-terminal like
chr10_-_80577285 9.05 ENSMUST00000038558.8
Klf16
Kruppel-like factor 16
chr13_-_23745511 9.01 ENSMUST00000091752.2
Hist1h3c
histone cluster 1, H3c
chr3_+_127553462 8.73 ENSMUST00000043108.4
4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr19_+_53600377 8.63 ENSMUST00000025930.9
Smc3
structural maintenance of chromosomes 3
chr18_+_10617768 8.60 ENSMUST00000002551.3
Snrpd1
small nuclear ribonucleoprotein D1
chr7_+_102441685 8.49 ENSMUST00000033283.9
Rrm1
ribonucleotide reductase M1
chr12_-_12941827 8.29 ENSMUST00000043396.7
Mycn
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr10_+_11281583 8.25 ENSMUST00000070300.4
Fbxo30
F-box protein 30
chr2_-_132253227 8.17 ENSMUST00000028817.6
Pcna
proliferating cell nuclear antigen
chr7_-_19359477 7.95 ENSMUST00000047036.8
Cd3eap
CD3E antigen, epsilon polypeptide associated protein
chr9_-_72491939 7.95 ENSMUST00000185151.1
ENSMUST00000085358.5
ENSMUST00000184125.1
ENSMUST00000183574.1
ENSMUST00000184831.1
Tex9
testis expressed gene 9
chr7_-_100121512 7.90 ENSMUST00000032969.7
Pold3
polymerase (DNA-directed), delta 3, accessory subunit
chr4_-_11966368 7.90 ENSMUST00000056050.4
ENSMUST00000108299.1
ENSMUST00000108297.2
Pdp1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr18_+_56707725 7.81 ENSMUST00000025486.8
Lmnb1
lamin B1
chr3_-_95217690 7.79 ENSMUST00000107209.1
Gabpb2
GA repeat binding protein, beta 2
chr9_+_96196246 7.74 ENSMUST00000165120.2
ENSMUST00000034982.9
Tfdp2
transcription factor Dp 2
chr5_+_110839973 7.72 ENSMUST00000066160.1
Chek2
checkpoint kinase 2
chr17_-_28486082 7.70 ENSMUST00000079413.3
Fkbp5
FK506 binding protein 5
chr17_-_23740301 7.63 ENSMUST00000024702.3
Paqr4
progestin and adipoQ receptor family member IV
chr13_-_21833575 7.62 ENSMUST00000081342.5
Hist1h2ap
histone cluster 1, H2ap
chr17_+_25016068 7.62 ENSMUST00000137386.1
Ift140
intraflagellar transport 140
chr9_+_103305156 7.62 ENSMUST00000035164.3
Topbp1
topoisomerase (DNA) II binding protein 1
chr3_-_95217877 7.46 ENSMUST00000136139.1
Gabpb2
GA repeat binding protein, beta 2
chrX_+_135839034 7.26 ENSMUST00000173804.1
ENSMUST00000113136.1
Gprasp2
G protein-coupled receptor associated sorting protein 2
chr2_-_34913976 7.26 ENSMUST00000028232.3
Phf19
PHD finger protein 19
chr6_-_4747157 7.23 ENSMUST00000090686.4
ENSMUST00000115579.1
ENSMUST00000115577.2
ENSMUST00000101677.3
ENSMUST00000004750.8
Sgce
sarcoglycan, epsilon
chr3_+_116594959 7.23 ENSMUST00000029571.8
Sass6
spindle assembly 6 homolog (C. elegans)
chr8_-_105707933 7.11 ENSMUST00000013299.9
Enkd1
enkurin domain containing 1
chr4_-_43046196 7.11 ENSMUST00000036462.5
Fam214b
family with sequence similarity 214, member B
chr7_-_48881596 7.08 ENSMUST00000119223.1
E2f8
E2F transcription factor 8
chr6_-_52183828 7.06 ENSMUST00000134831.1
Hoxa3
homeobox A3
chr6_-_148946146 6.95 ENSMUST00000132696.1
Fam60a
family with sequence similarity 60, member A
chrX_+_135885851 6.90 ENSMUST00000180025.1
ENSMUST00000068755.7
ENSMUST00000148374.1
Bhlhb9
basic helix-loop-helix domain containing, class B9
chrX_-_59134421 6.83 ENSMUST00000033473.5
Fgf13
fibroblast growth factor 13
chr18_-_64489042 6.71 ENSMUST00000025484.7
Fech
ferrochelatase
chr9_-_102354685 6.65 ENSMUST00000035129.7
ENSMUST00000085169.5
Ephb1
Eph receptor B1
chr9_-_58741543 6.63 ENSMUST00000098674.4
2410076I21Rik
RIKEN cDNA 2410076I21 gene
chr17_+_28801090 6.63 ENSMUST00000004985.9
Brpf3
bromodomain and PHD finger containing, 3
chr13_-_21783391 6.49 ENSMUST00000099704.3
Hist1h3i
histone cluster 1, H3i
chr9_-_36726374 6.48 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
Chek1
checkpoint kinase 1
chr9_+_13827708 6.39 ENSMUST00000059579.5
Fam76b
family with sequence similarity 76, member B
chr7_+_126781483 6.37 ENSMUST00000172352.1
ENSMUST00000094037.4
Tbx6
T-box 6
chr17_+_29490812 6.31 ENSMUST00000024811.6
Pim1
proviral integration site 1
chr19_-_53371766 6.22 ENSMUST00000086887.1
Gm10197
predicted gene 10197
chr16_-_20426322 6.17 ENSMUST00000115547.2
ENSMUST00000096199.4
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr10_+_128232065 6.15 ENSMUST00000055539.4
ENSMUST00000105244.1
ENSMUST00000105243.2
ENSMUST00000125289.1
ENSMUST00000105242.1
Timeless
timeless circadian clock 1
chr2_+_91650116 6.04 ENSMUST00000111331.2
Arhgap1
Rho GTPase activating protein 1
chr15_+_61985540 6.02 ENSMUST00000159327.1
ENSMUST00000167731.1
Myc
myelocytomatosis oncogene
chr5_+_57718021 5.99 ENSMUST00000094783.3
ENSMUST00000068110.7
Pcdh7
protocadherin 7
chr6_-_4747019 5.97 ENSMUST00000126151.1
ENSMUST00000133306.1
ENSMUST00000123907.1
Sgce
sarcoglycan, epsilon
chr12_+_55836365 5.94 ENSMUST00000059250.6
Brms1l
breast cancer metastasis-suppressor 1-like
chr5_+_114130386 5.92 ENSMUST00000031587.6
Ung
uracil DNA glycosylase
chr7_-_45395672 5.89 ENSMUST00000074575.7
Snrnp70
small nuclear ribonucleoprotein 70 (U1)
chr4_+_100776664 5.85 ENSMUST00000030257.8
ENSMUST00000097955.2
Cachd1
cache domain containing 1
chr15_+_61985377 5.84 ENSMUST00000161976.1
ENSMUST00000022971.7
Myc
myelocytomatosis oncogene
chr16_-_20425881 5.83 ENSMUST00000077867.3
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr4_-_132843111 5.79 ENSMUST00000105919.1
ENSMUST00000030702.7
Ppp1r8
protein phosphatase 1, regulatory (inhibitor) subunit 8
chr5_-_110839757 5.76 ENSMUST00000056937.5
Hscb
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chrX_+_42150672 5.73 ENSMUST00000069619.7
Stag2
stromal antigen 2
chr17_-_35046726 5.61 ENSMUST00000097338.4
Msh5
mutS homolog 5 (E. coli)
chr13_+_21716385 5.60 ENSMUST00000070124.3
Hist1h2ai
histone cluster 1, H2ai
chr3_-_95217741 5.58 ENSMUST00000107204.1
Gabpb2
GA repeat binding protein, beta 2
chr7_+_79392305 5.55 ENSMUST00000117227.1
ENSMUST00000118959.1
ENSMUST00000036865.6
Fanci
Fanconi anemia, complementation group I
chr8_+_95633500 5.41 ENSMUST00000034094.9
Gins3
GINS complex subunit 3 (Psf3 homolog)
chr5_-_136135989 5.27 ENSMUST00000150406.1
ENSMUST00000006301.4
Lrwd1
leucine-rich repeats and WD repeat domain containing 1
chr17_-_71475285 5.16 ENSMUST00000127430.1
Smchd1
SMC hinge domain containing 1
chr9_-_108452377 5.14 ENSMUST00000035232.7
Klhdc8b
kelch domain containing 8B
chr11_-_87404380 5.14 ENSMUST00000067692.6
Rad51c
RAD51 homolog C
chr2_+_91650169 5.01 ENSMUST00000090614.4
Arhgap1
Rho GTPase activating protein 1
chr4_-_93335510 4.98 ENSMUST00000066774.4
Tusc1
tumor suppressor candidate 1
chr9_-_13827029 4.94 ENSMUST00000148086.1
ENSMUST00000034398.5
Cep57
centrosomal protein 57
chr19_-_5964132 4.87 ENSMUST00000025752.7
ENSMUST00000165143.1
Pola2
polymerase (DNA directed), alpha 2
chr15_-_8444449 4.78 ENSMUST00000052965.6
Nipbl
Nipped-B homolog (Drosophila)
chr12_+_71016658 4.77 ENSMUST00000125125.1
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr12_+_112644828 4.76 ENSMUST00000021728.4
ENSMUST00000109755.3
Siva1
SIVA1, apoptosis-inducing factor
chr2_+_132816141 4.66 ENSMUST00000028831.8
ENSMUST00000066559.5
Mcm8
minichromosome maintenance deficient 8 (S. cerevisiae)
chr5_-_110839575 4.60 ENSMUST00000145318.1
Hscb
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr2_-_152398046 4.59 ENSMUST00000063332.8
ENSMUST00000182625.1
Sox12
SRY-box containing gene 12
chr4_-_133967893 4.54 ENSMUST00000100472.3
ENSMUST00000136327.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr13_-_47106176 4.51 ENSMUST00000021807.6
ENSMUST00000135278.1
Dek
DEK oncogene (DNA binding)
chrX_+_68678541 4.29 ENSMUST00000088546.5
Fmr1
fragile X mental retardation syndrome 1
chr9_-_106887000 4.28 ENSMUST00000055843.7
Rbm15b
RNA binding motif protein 15B
chr1_-_38129618 4.22 ENSMUST00000027251.6
Rev1
REV1 homolog (S. cerevisiae)
chr1_+_183297060 4.21 ENSMUST00000109166.2
Aida
axin interactor, dorsalization associated
chr7_-_48881032 4.21 ENSMUST00000058745.8
E2f8
E2F transcription factor 8

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f2_E2f5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
25.1 75.3 GO:0072488 ammonium transmembrane transport(GO:0072488)
15.7 110.0 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
14.8 147.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
10.9 21.7 GO:0006272 leading strand elongation(GO:0006272)
10.1 30.3 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
9.7 106.9 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
9.0 36.1 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
9.0 44.9 GO:0034421 post-translational protein acetylation(GO:0034421)
7.8 23.5 GO:0045004 DNA replication proofreading(GO:0045004)
7.2 107.9 GO:0010216 maintenance of DNA methylation(GO:0010216)
7.1 7.1 GO:0010159 specification of organ position(GO:0010159)
6.1 36.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
5.8 57.9 GO:1902969 mitotic DNA replication(GO:1902969)
5.2 31.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
5.2 5.2 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
4.5 18.0 GO:0000076 DNA replication checkpoint(GO:0000076)
4.3 34.1 GO:0051572 negative regulation of histone H3-K4 methylation(GO:0051572)
4.2 4.2 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
4.1 102.5 GO:0006270 DNA replication initiation(GO:0006270)
3.9 3.9 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
3.8 69.1 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
3.8 34.1 GO:0090166 Golgi disassembly(GO:0090166)
3.8 52.6 GO:0033504 floor plate development(GO:0033504)
3.7 21.9 GO:0019985 translesion synthesis(GO:0019985)
3.5 10.6 GO:0045660 positive regulation of neutrophil differentiation(GO:0045660)
3.4 13.4 GO:0046125 pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
3.0 24.2 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
3.0 21.0 GO:0042148 strand invasion(GO:0042148)
3.0 11.9 GO:0044330 canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330) lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
2.7 31.8 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
2.6 7.8 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
2.5 10.2 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
2.5 10.0 GO:1904306 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
2.5 39.7 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
2.4 24.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
2.3 7.0 GO:0099547 regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254)
2.3 6.8 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
2.1 27.8 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
2.1 10.6 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
2.1 6.2 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
2.0 7.9 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
2.0 5.9 GO:0006285 base-excision repair, AP site formation(GO:0006285)
1.9 19.5 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
1.9 16.9 GO:0021631 optic nerve morphogenesis(GO:0021631)
1.8 11.0 GO:1903336 endosome localization(GO:0032439) negative regulation of vacuolar transport(GO:1903336)
1.8 14.2 GO:2000232 regulation of rRNA processing(GO:2000232)
1.8 12.3 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
1.6 61.7 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
1.6 27.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
1.6 20.7 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
1.6 19.0 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
1.6 11.0 GO:0036337 Fas signaling pathway(GO:0036337)
1.5 15.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
1.5 4.4 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
1.5 10.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
1.5 16.3 GO:0000212 meiotic spindle organization(GO:0000212)
1.4 14.5 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
1.4 16.8 GO:0033280 response to vitamin D(GO:0033280)
1.3 3.8 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
1.3 3.8 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
1.3 10.2 GO:0070294 renal sodium ion absorption(GO:0070294)
1.3 3.8 GO:0006597 spermine biosynthetic process(GO:0006597)
1.2 8.7 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
1.2 4.8 GO:0061010 gall bladder development(GO:0061010)
1.1 15.6 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
1.1 5.3 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
1.0 6.8 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
1.0 10.6 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
1.0 4.8 GO:0034770 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.9 8.3 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.9 22.2 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.9 75.6 GO:0006342 chromatin silencing(GO:0006342)
0.8 2.5 GO:1903632 positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.8 10.0 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.8 6.4 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.8 3.8 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.8 4.5 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.7 24.7 GO:0006284 base-excision repair(GO:0006284)
0.7 7.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.7 6.9 GO:0051026 chiasma assembly(GO:0051026)
0.7 6.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.7 4.1 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.6 15.7 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.6 4.4 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.6 8.0 GO:0007343 egg activation(GO:0007343)
0.6 2.4 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.6 2.9 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.6 3.5 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.6 4.0 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.6 2.3 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.6 3.3 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.5 1.6 GO:0043987 histone H3-S10 phosphorylation(GO:0043987) histone H3-S28 phosphorylation(GO:0043988)
0.5 1.6 GO:0060382 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.5 1.5 GO:0060720 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
0.5 26.8 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.5 35.7 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.5 4.8 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.5 3.8 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.5 13.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.5 1.4 GO:0019389 glucuronoside metabolic process(GO:0019389)
0.5 1.8 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.4 8.0 GO:0009303 rRNA transcription(GO:0009303)
0.4 9.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.4 2.6 GO:0006020 inositol metabolic process(GO:0006020)
0.4 1.4 GO:0032789 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.4 2.1 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.3 18.8 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.3 10.4 GO:0007099 centriole replication(GO:0007099)
0.3 4.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.3 2.4 GO:0007000 nucleolus organization(GO:0007000)
0.3 0.6 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.3 3.2 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.3 11.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.3 2.9 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.3 5.5 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818)
0.3 0.8 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.3 9.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.2 0.5 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.2 1.9 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2 0.9 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.2 1.8 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.2 23.7 GO:0006334 nucleosome assembly(GO:0006334)
0.2 1.1 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.2 1.9 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.2 4.9 GO:0034453 microtubule anchoring(GO:0034453)
0.2 12.5 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.2 1.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.2 1.9 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2 0.8 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.2 1.2 GO:0072697 protein localization to cell cortex(GO:0072697)
0.2 16.4 GO:0035308 negative regulation of protein dephosphorylation(GO:0035308)
0.2 6.9 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 3.1 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.1 5.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 3.2 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1 0.5 GO:0010286 heat acclimation(GO:0010286)
0.1 1.2 GO:0072401 signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422)
0.1 6.1 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 2.2 GO:0032098 regulation of appetite(GO:0032098)
0.1 1.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.8 GO:0010793 regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197)
0.1 2.9 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.1 2.1 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.1 1.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 1.5 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.1 5.5 GO:0019228 neuronal action potential(GO:0019228)
0.1 0.7 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.1 3.1 GO:0048520 positive regulation of behavior(GO:0048520)
0.1 0.2 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 9.2 GO:0016579 protein deubiquitination(GO:0016579)
0.1 1.7 GO:0021511 spinal cord patterning(GO:0021511)
0.1 3.4 GO:0016925 protein sumoylation(GO:0016925)
0.1 3.2 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 1.0 GO:0042407 cristae formation(GO:0042407)
0.1 7.1 GO:0030010 establishment of cell polarity(GO:0030010)
0.1 3.2 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.1 2.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 0.7 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 15.1 GO:0007018 microtubule-based movement(GO:0007018)
0.1 0.7 GO:1904251 regulation of bile acid metabolic process(GO:1904251)
0.0 3.6 GO:0048477 oogenesis(GO:0048477)
0.0 3.2 GO:0051225 spindle assembly(GO:0051225)
0.0 3.0 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.6 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 1.9 GO:0031076 embryonic camera-type eye development(GO:0031076)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 1.2 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.5 GO:0048148 behavioral response to cocaine(GO:0048148)
0.0 2.6 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.5 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.3 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.1 GO:0060056 mammary gland involution(GO:0060056)
0.0 4.9 GO:0048511 rhythmic process(GO:0048511)
0.0 0.5 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.9 GO:0021510 spinal cord development(GO:0021510)
0.0 0.3 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 1.7 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
13.8 69.1 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
12.1 182.2 GO:0042555 MCM complex(GO:0042555)
8.8 26.4 GO:0000811 GINS complex(GO:0000811)
7.1 35.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
5.9 29.4 GO:0035189 Rb-E2F complex(GO:0035189)
5.9 29.3 GO:0031298 replication fork protection complex(GO:0031298)
5.0 44.9 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
4.7 14.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
4.0 12.1 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
3.7 18.4 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
2.8 14.2 GO:0001651 dense fibrillar component(GO:0001651)
2.8 155.2 GO:0005657 replication fork(GO:0005657)
2.6 10.5 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
2.6 10.4 GO:0032389 MutLalpha complex(GO:0032389)
2.1 18.7 GO:0030991 intraciliary transport particle A(GO:0030991)
2.1 20.8 GO:0000796 condensin complex(GO:0000796)
2.0 10.0 GO:0033553 rDNA heterochromatin(GO:0033553)
1.9 5.6 GO:0035061 interchromatin granule(GO:0035061)
1.8 11.0 GO:0097443 sorting endosome(GO:0097443)
1.8 7.0 GO:0019034 viral replication complex(GO:0019034) dendritic filopodium(GO:1902737)
1.8 5.3 GO:0031933 telomeric heterochromatin(GO:0031933)
1.7 8.6 GO:0034715 pICln-Sm protein complex(GO:0034715)
1.6 21.9 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
1.4 8.6 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
1.3 19.8 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
1.3 7.6 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
1.2 7.2 GO:0098536 deuterosome(GO:0098536)
1.1 7.8 GO:0005638 lamin filament(GO:0005638)
1.0 5.2 GO:0001740 Barr body(GO:0001740)
1.0 53.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.9 2.8 GO:0005683 U7 snRNP(GO:0005683)
0.9 9.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.8 21.6 GO:0035861 site of double-strand break(GO:0035861)
0.8 19.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.7 6.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.7 120.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.7 5.9 GO:0000243 commitment complex(GO:0000243)
0.6 12.9 GO:0070822 Sin3-type complex(GO:0070822)
0.6 40.3 GO:0044815 nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.6 9.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.6 7.6 GO:0001673 male germ cell nucleus(GO:0001673)
0.5 34.1 GO:0005871 kinesin complex(GO:0005871)
0.5 8.0 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.5 1.5 GO:0031251 PAN complex(GO:0031251)
0.5 52.1 GO:0005814 centriole(GO:0005814)
0.5 2.7 GO:0044530 supraspliceosomal complex(GO:0044530)
0.4 11.9 GO:0005719 nuclear euchromatin(GO:0005719)
0.4 1.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.4 0.8 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.4 3.2 GO:0070652 HAUS complex(GO:0070652)
0.4 33.6 GO:0005776 autophagosome(GO:0005776)
0.4 10.7 GO:0051233 spindle midzone(GO:0051233)
0.4 6.7 GO:0032433 filopodium tip(GO:0032433)
0.3 3.1 GO:0000801 central element(GO:0000801)
0.3 35.5 GO:0000781 chromosome, telomeric region(GO:0000781)
0.3 20.1 GO:0072686 mitotic spindle(GO:0072686)
0.3 4.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.3 29.5 GO:0016363 nuclear matrix(GO:0016363)
0.3 1.2 GO:0034709 methylosome(GO:0034709)
0.3 2.9 GO:0031080 nuclear pore outer ring(GO:0031080)
0.3 1.4 GO:0000791 euchromatin(GO:0000791)
0.3 3.4 GO:0044232 organelle membrane contact site(GO:0044232)
0.3 4.6 GO:0032993 protein-DNA complex(GO:0032993)
0.2 63.1 GO:0005667 transcription factor complex(GO:0005667)
0.2 3.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.2 30.0 GO:0005819 spindle(GO:0005819)
0.2 150.0 GO:0005694 chromosome(GO:0005694)
0.2 15.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 11.0 GO:0016605 PML body(GO:0016605)
0.2 2.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.2 8.1 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 0.5 GO:0001652 granular component(GO:0001652)
0.2 2.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 1.4 GO:1904115 axon cytoplasm(GO:1904115)
0.1 3.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 7.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 1.1 GO:0071565 nBAF complex(GO:0071565)
0.1 1.9 GO:0097470 ribbon synapse(GO:0097470)
0.1 2.9 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.1 1.0 GO:0061617 MICOS complex(GO:0061617)
0.1 2.2 GO:0034451 centriolar satellite(GO:0034451)
0.1 1.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 2.9 GO:0043204 perikaryon(GO:0043204)
0.1 6.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 10.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 2.4 GO:0015030 Cajal body(GO:0015030)
0.1 1.3 GO:0043194 axon initial segment(GO:0043194)
0.1 3.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 28.3 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 0.6 GO:0097440 apical dendrite(GO:0097440)
0.1 168.5 GO:0005829 cytosol(GO:0005829)
0.0 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 1.4 GO:0005844 polysome(GO:0005844)
0.0 56.1 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 12.0 GO:0005730 nucleolus(GO:0005730)
0.0 0.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 2.4 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 63.2 GO:0005634 nucleus(GO:0005634)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
16.5 99.3 GO:0010997 anaphase-promoting complex binding(GO:0010997)
13.8 69.1 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
13.6 81.9 GO:0031493 nucleosomal histone binding(GO:0031493)
7.2 28.9 GO:0071987 WD40-repeat domain binding(GO:0071987)
5.9 41.5 GO:0000150 recombinase activity(GO:0000150)
5.7 79.7 GO:0003688 DNA replication origin binding(GO:0003688)
5.6 22.4 GO:0048256 flap endonuclease activity(GO:0048256)
5.2 36.4 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
4.1 44.9 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
4.0 24.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
4.0 36.1 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
3.4 13.4 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
3.1 9.4 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
3.1 24.9 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
3.1 15.3 GO:0000405 bubble DNA binding(GO:0000405)
3.0 15.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
3.0 18.0 GO:0044547 DNA topoisomerase binding(GO:0044547)
2.7 8.2 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
2.6 121.8 GO:0003678 DNA helicase activity(GO:0003678)
2.6 75.3 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
2.5 10.2 GO:0031711 beta-adrenergic receptor activity(GO:0004939) bradykinin receptor binding(GO:0031711)
2.4 67.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
2.4 16.9 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
2.2 6.7 GO:0030350 iron-responsive element binding(GO:0030350)
2.2 6.5 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
2.0 36.8 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
2.0 10.0 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
2.0 7.9 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
1.9 17.3 GO:1990446 U1 snRNP binding(GO:1990446)
1.7 13.9 GO:0032404 mismatch repair complex binding(GO:0032404)
1.7 12.0 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
1.6 11.0 GO:0032184 SUMO polymer binding(GO:0032184)
1.5 5.9 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
1.3 3.8 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
1.2 4.7 GO:0036033 mediator complex binding(GO:0036033)
1.2 7.0 GO:0033592 RNA strand annealing activity(GO:0033592)
1.2 10.5 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
1.2 36.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
1.1 10.0 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
1.0 9.3 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505)
0.9 3.8 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.8 9.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.8 2.4 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.8 20.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.7 5.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.7 1.4 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.7 6.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.6 1.8 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.6 18.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.6 156.2 GO:0001047 core promoter binding(GO:0001047)
0.5 32.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.5 28.5 GO:0070491 repressing transcription factor binding(GO:0070491)
0.5 1.4 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.5 3.8 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.5 6.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.4 15.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.4 6.3 GO:0031386 protein tag(GO:0031386)
0.4 7.1 GO:0071837 HMG box domain binding(GO:0071837)
0.4 7.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.4 2.3 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.4 40.0 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.3 34.1 GO:0003777 microtubule motor activity(GO:0003777)
0.3 4.9 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.3 2.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.3 1.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.3 18.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.3 30.9 GO:0051087 chaperone binding(GO:0051087)
0.3 1.9 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.3 2.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.3 9.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.3 5.7 GO:0008432 JUN kinase binding(GO:0008432)
0.2 5.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.2 19.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.2 25.6 GO:0004386 helicase activity(GO:0004386)
0.2 38.6 GO:0042393 histone binding(GO:0042393)
0.2 0.7 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.2 5.1 GO:0004407 histone deacetylase activity(GO:0004407)
0.2 0.2 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.2 1.0 GO:0051425 PTB domain binding(GO:0051425)
0.2 9.1 GO:0050699 WW domain binding(GO:0050699)
0.2 4.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.2 2.4 GO:0031996 thioesterase binding(GO:0031996)
0.2 10.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 1.4 GO:0001055 RNA polymerase II activity(GO:0001055)
0.2 0.6 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2 4.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 4.1 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.2 1.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.7 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 1.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 6.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 7.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 28.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 1.1 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.1 40.6 GO:0005096 GTPase activator activity(GO:0005096)
0.1 4.5 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 2.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.4 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 2.7 GO:0097602 cullin family protein binding(GO:0097602)
0.1 3.2 GO:0030332 cyclin binding(GO:0030332)
0.1 3.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 2.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 1.9 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 1.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 48.9 GO:0046982 protein heterodimerization activity(GO:0046982)
0.1 5.3 GO:0005080 protein kinase C binding(GO:0005080)
0.1 1.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.3 GO:0031402 sodium ion binding(GO:0031402)
0.1 1.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 9.3 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1 0.5 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 2.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 4.1 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 3.8 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 4.2 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 12.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 1.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.2 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 2.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 5.1 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 10.5 GO:0008270 zinc ion binding(GO:0008270)
0.0 1.6 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 1.9 GO:0008047 enzyme activator activity(GO:0008047)
0.0 0.5 GO:0002039 p53 binding(GO:0002039)
0.0 1.5 GO:0008565 protein transporter activity(GO:0008565)
0.0 1.4 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.7 GO:0051117 ATPase binding(GO:0051117)
0.0 11.1 GO:0005524 ATP binding(GO:0005524)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
8.4 75.9 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
8.3 133.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
6.0 271.2 PID ATR PATHWAY ATR signaling pathway
1.9 158.5 PID E2F PATHWAY E2F transcription factor network
1.5 52.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
1.3 36.4 PID S1P S1P1 PATHWAY S1P1 pathway
1.0 26.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
1.0 48.5 PID PLK1 PATHWAY PLK1 signaling events
0.9 95.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.9 11.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.9 12.8 ST JAK STAT PATHWAY Jak-STAT Pathway
0.7 21.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.7 27.8 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.5 8.2 PID BARD1 PATHWAY BARD1 signaling events
0.4 28.8 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.4 12.3 PID AURORA B PATHWAY Aurora B signaling
0.4 10.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.3 29.9 PID CMYB PATHWAY C-MYB transcription factor network
0.3 13.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.2 6.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 3.1 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 3.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 7.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 7.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 3.9 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 4.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 4.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 6.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 7.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 1.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 3.2 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 3.3 PID P53 REGULATION PATHWAY p53 pathway
0.1 2.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 2.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.5 PID TNF PATHWAY TNF receptor signaling pathway
0.0 2.4 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 1.9 PID P73PATHWAY p73 transcription factor network
0.0 1.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
14.4 230.9 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
12.5 224.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
11.5 80.6 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
5.7 28.5 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
5.3 10.6 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
5.0 69.4 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
3.8 15.4 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
3.1 36.8 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
2.7 24.6 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
2.4 14.5 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
1.9 32.0 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
1.4 38.3 REACTOME KINESINS Genes involved in Kinesins
1.2 24.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
1.1 52.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
1.1 10.6 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
1.0 58.9 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
1.0 29.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.7 12.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.7 13.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.6 7.9 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.4 13.8 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.4 10.0 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.4 5.7 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.4 8.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.4 4.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.3 13.6 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.3 6.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.3 15.6 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.3 57.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.3 9.1 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.2 9.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 23.5 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.2 3.8 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.2 2.1 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.2 10.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.2 4.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 5.5 REACTOME CHROMOSOME MAINTENANCE Genes involved in Chromosome Maintenance
0.1 4.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 3.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 2.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 3.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.7 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.9 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.9 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.0 0.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.6 REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH Genes involved in NCAM signaling for neurite out-growth
0.0 2.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors