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GSE58827: Dynamics of the Mouse Liver

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Results for E2f3

Z-value: 1.30

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Transcription factors associated with E2f3

Gene Symbol Gene ID Gene Info
E2f3
ENSMUSG00000016477.11 E2F transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2f3mm10_v2_chr13_-_29984219_299843530.798.1e-09Click!

Activity profile of E2f3 motif

Sorted Z-values of E2f3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_6730412 7.63 ENSMUST00000051209.4
Peg3
paternally expressed 3
chr11_+_11685909 7.35 ENSMUST00000065433.5
Ikzf1
IKAROS family zinc finger 1
chr4_+_46450892 6.22 ENSMUST00000102926.4
Anp32b
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr2_+_118111876 6.15 ENSMUST00000039559.8
Thbs1
thrombospondin 1
chr12_-_4874341 5.81 ENSMUST00000137337.1
ENSMUST00000045921.7
Mfsd2b
major facilitator superfamily domain containing 2B
chr3_-_84480419 5.46 ENSMUST00000107689.1
Fhdc1
FH2 domain containing 1
chr10_+_20347788 4.77 ENSMUST00000169712.1
Mtfr2
mitochondrial fission regulator 2
chrX_+_135993820 4.74 ENSMUST00000058119.7
Arxes2
adipocyte-related X-chromosome expressed sequence 2
chr2_+_109280738 4.68 ENSMUST00000028527.7
Kif18a
kinesin family member 18A
chr7_-_100863373 4.53 ENSMUST00000142885.1
ENSMUST00000008462.3
Relt
RELT tumor necrosis factor receptor
chr2_-_127133909 4.22 ENSMUST00000110387.3
Ncaph
non-SMC condensin I complex, subunit H
chrX_-_51205773 4.16 ENSMUST00000114875.1
Mbnl3
muscleblind-like 3 (Drosophila)
chr13_+_117220584 4.15 ENSMUST00000022242.7
Emb
embigin
chr15_+_102296256 4.06 ENSMUST00000064924.4
Espl1
extra spindle poles-like 1 (S. cerevisiae)
chr12_-_69228167 4.02 ENSMUST00000021359.5
Pole2
polymerase (DNA directed), epsilon 2 (p59 subunit)
chr17_+_35841668 3.86 ENSMUST00000174124.1
Mdc1
mediator of DNA damage checkpoint 1
chr15_-_79605084 3.69 ENSMUST00000023065.6
Dmc1
DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination
chr7_+_113513854 3.64 ENSMUST00000067929.8
ENSMUST00000129087.1
ENSMUST00000164745.1
ENSMUST00000136158.1
Far1
fatty acyl CoA reductase 1
chr3_+_69004969 3.61 ENSMUST00000136502.1
ENSMUST00000107803.1
Smc4
structural maintenance of chromosomes 4
chrX_-_51205990 3.59 ENSMUST00000114876.2
Mbnl3
muscleblind-like 3 (Drosophila)
chr7_+_13278778 3.44 ENSMUST00000098814.4
ENSMUST00000146998.1
ENSMUST00000185145.1
Lig1
ligase I, DNA, ATP-dependent
chr3_+_69004711 3.25 ENSMUST00000042901.8
Smc4
structural maintenance of chromosomes 4
chr4_+_115000174 3.21 ENSMUST00000129957.1
Stil
Scl/Tal1 interrupting locus
chrX_-_73659724 3.10 ENSMUST00000114473.1
ENSMUST00000002087.7
Pnck
pregnancy upregulated non-ubiquitously expressed CaM kinase
chr9_-_39603635 3.08 ENSMUST00000119722.1
AW551984
expressed sequence AW551984
chr18_-_52529692 3.07 ENSMUST00000025409.7
Lox
lysyl oxidase
chr2_+_103969528 3.04 ENSMUST00000123437.1
ENSMUST00000163256.1
Lmo2
LIM domain only 2
chr18_+_11657349 3.00 ENSMUST00000047322.6
Rbbp8
retinoblastoma binding protein 8
chr11_-_101551837 2.98 ENSMUST00000017290.4
Brca1
breast cancer 1
chr5_-_148399901 2.82 ENSMUST00000048116.8
Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chrX_+_20703906 2.76 ENSMUST00000033383.2
Usp11
ubiquitin specific peptidase 11
chr12_+_24708241 2.70 ENSMUST00000020980.5
Rrm2
ribonucleotide reductase M2
chrX_-_73660047 2.63 ENSMUST00000114472.1
Pnck
pregnancy upregulated non-ubiquitously expressed CaM kinase
chr4_+_115000156 2.58 ENSMUST00000030490.6
Stil
Scl/Tal1 interrupting locus
chr13_-_51793650 2.50 ENSMUST00000110040.2
ENSMUST00000021900.7
Sema4d
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr12_-_11265768 2.47 ENSMUST00000166117.1
Gen1
Gen homolog 1, endonuclease (Drosophila)
chr4_-_43046196 2.47 ENSMUST00000036462.5
Fam214b
family with sequence similarity 214, member B
chr17_+_26917091 2.42 ENSMUST00000078961.4
Kifc5b
kinesin family member C5B
chr1_-_95667555 2.41 ENSMUST00000043336.4
St8sia4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr3_-_69004475 2.40 ENSMUST00000154741.1
ENSMUST00000148031.1
Ift80
intraflagellar transport 80
chrX_-_150814265 2.38 ENSMUST00000026302.6
ENSMUST00000129768.1
ENSMUST00000112699.2
Maged2
melanoma antigen, family D, 2
chr15_+_84232030 2.37 ENSMUST00000023072.6
Parvb
parvin, beta
chr18_-_12941777 2.36 ENSMUST00000122175.1
Osbpl1a
oxysterol binding protein-like 1A
chr5_+_108132885 2.35 ENSMUST00000047677.7
Ccdc18
coiled-coil domain containing 18
chr9_+_64281575 2.35 ENSMUST00000034964.6
Tipin
timeless interacting protein
chr5_+_34573664 2.34 ENSMUST00000114338.2
Add1
adducin 1 (alpha)
chr12_+_86678685 2.26 ENSMUST00000021681.3
Vash1
vasohibin 1
chr4_-_133967235 2.22 ENSMUST00000123234.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr8_+_117498272 2.16 ENSMUST00000081232.7
Plcg2
phospholipase C, gamma 2
chr3_+_33799791 2.12 ENSMUST00000099153.3
Ttc14
tetratricopeptide repeat domain 14
chr7_+_113513829 2.11 ENSMUST00000033018.8
Far1
fatty acyl CoA reductase 1
chr1_-_191575534 2.10 ENSMUST00000027933.5
Dtl
denticleless homolog (Drosophila)
chr5_+_34573808 2.07 ENSMUST00000001108.4
ENSMUST00000114340.2
Add1
adducin 1 (alpha)
chr6_+_29694204 2.07 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33
tetraspanin 33
chr12_+_4917376 2.06 ENSMUST00000045664.5
Atad2b
ATPase family, AAA domain containing 2B
chr8_-_94876269 2.04 ENSMUST00000046461.7
Dok4
docking protein 4
chr2_-_37703845 2.03 ENSMUST00000155237.1
Strbp
spermatid perinuclear RNA binding protein
chr4_+_43957678 2.01 ENSMUST00000107855.1
Glipr2
GLI pathogenesis-related 2
chr19_+_53600377 1.98 ENSMUST00000025930.9
Smc3
structural maintenance of chromosomes 3
chr3_+_33800158 1.96 ENSMUST00000139880.1
ENSMUST00000076916.6
ENSMUST00000142280.1
ENSMUST00000117915.1
ENSMUST00000108210.2
Ttc14
tetratricopeptide repeat domain 14
chr5_+_5573952 1.96 ENSMUST00000101627.2
Gm8773
predicted gene 8773
chrX_+_101274023 1.88 ENSMUST00000117706.1
Med12
mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)
chr3_-_41742471 1.86 ENSMUST00000026866.8
Sclt1
sodium channel and clathrin linker 1
chr3_+_88607742 1.82 ENSMUST00000175903.1
Arhgef2
rho/rac guanine nucleotide exchange factor (GEF) 2
chrX_+_101274198 1.82 ENSMUST00000117203.1
ENSMUST00000087948.4
ENSMUST00000087956.5
Med12
mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)
chr4_-_129440800 1.77 ENSMUST00000053042.5
ENSMUST00000106046.1
Zbtb8b
zinc finger and BTB domain containing 8b
chr1_-_134079114 1.77 ENSMUST00000020692.6
Btg2
B cell translocation gene 2, anti-proliferative
chr10_-_93589621 1.76 ENSMUST00000020203.6
Snrpf
small nuclear ribonucleoprotein polypeptide F
chr14_-_60251473 1.73 ENSMUST00000041905.6
Nupl1
nucleoporin like 1
chr17_+_34398802 1.68 ENSMUST00000114175.1
ENSMUST00000078615.5
ENSMUST00000139063.1
ENSMUST00000097348.2
BC051142
cDNA sequence BC051142
chr9_+_57072024 1.68 ENSMUST00000169879.1
Sin3a
transcriptional regulator, SIN3A (yeast)
chr13_+_37826904 1.68 ENSMUST00000149745.1
Rreb1
ras responsive element binding protein 1
chr11_+_32347800 1.63 ENSMUST00000038753.5
Sh3pxd2b
SH3 and PX domains 2B
chr4_+_32615473 1.63 ENSMUST00000178925.1
ENSMUST00000029950.3
Casp8ap2
caspase 8 associated protein 2
chr3_+_103576081 1.58 ENSMUST00000183637.1
ENSMUST00000117221.2
ENSMUST00000118117.1
ENSMUST00000118563.2
Syt6
synaptotagmin VI
chr10_+_14523062 1.58 ENSMUST00000096020.5
Gm10335
predicted gene 10335
chr17_+_47593444 1.57 ENSMUST00000182209.1
Ccnd3
cyclin D3
chr9_+_109875541 1.56 ENSMUST00000094324.3
Cdc25a
cell division cycle 25A
chr16_+_34690548 1.52 ENSMUST00000023532.6
Ccdc14
coiled-coil domain containing 14
chr2_+_180598219 1.52 ENSMUST00000103059.1
Col9a3
collagen, type IX, alpha 3
chr3_-_95217690 1.52 ENSMUST00000107209.1
Gabpb2
GA repeat binding protein, beta 2
chr10_-_80918212 1.51 ENSMUST00000057623.7
ENSMUST00000179022.1
Lmnb2
lamin B2
chr17_-_24658425 1.50 ENSMUST00000095544.4
Npw
neuropeptide W
chr3_+_59006978 1.49 ENSMUST00000040325.7
ENSMUST00000164225.1
ENSMUST00000040846.8
ENSMUST00000029393.8
Med12l
mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)-like
chrX_-_105929397 1.49 ENSMUST00000113573.1
ENSMUST00000130980.1
Atrx
alpha thalassemia/mental retardation syndrome X-linked homolog (human)
chr16_+_91485295 1.48 ENSMUST00000129878.1
Ifnar1
interferon (alpha and beta) receptor 1
chr13_-_21531084 1.47 ENSMUST00000045228.5
Zkscan8
zinc finger with KRAB and SCAN domains 8
chr16_-_43889669 1.47 ENSMUST00000023387.7
Qtrtd1
queuine tRNA-ribosyltransferase domain containing 1
chr2_-_180225812 1.45 ENSMUST00000015791.5
Lama5
laminin, alpha 5
chrX_-_105929333 1.45 ENSMUST00000134507.1
ENSMUST00000137453.1
ENSMUST00000150914.1
Atrx
alpha thalassemia/mental retardation syndrome X-linked homolog (human)
chr16_-_78376758 1.43 ENSMUST00000023570.7
Btg3
B cell translocation gene 3
chr19_+_40894692 1.38 ENSMUST00000050092.6
Zfp518a
zinc finger protein 518A
chr16_-_4719148 1.35 ENSMUST00000115851.3
Nmral1
NmrA-like family domain containing 1
chr3_-_95217741 1.33 ENSMUST00000107204.1
Gabpb2
GA repeat binding protein, beta 2
chr19_+_21778325 1.29 ENSMUST00000096194.2
ENSMUST00000025663.6
Tmem2
transmembrane protein 2
chrX_-_105929206 1.28 ENSMUST00000134381.1
ENSMUST00000154866.1
Atrx
alpha thalassemia/mental retardation syndrome X-linked homolog (human)
chrX_-_102189371 1.27 ENSMUST00000033683.7
Rps4x
ribosomal protein S4, X-linked
chr3_+_41742615 1.27 ENSMUST00000146165.1
ENSMUST00000119572.1
ENSMUST00000108065.2
ENSMUST00000120167.1
ENSMUST00000026867.7
ENSMUST00000026868.7
D3Ertd751e
DNA segment, Chr 3, ERATO Doi 751, expressed
chr3_-_95217877 1.26 ENSMUST00000136139.1
Gabpb2
GA repeat binding protein, beta 2
chr2_+_150786735 1.25 ENSMUST00000045441.7
Pygb
brain glycogen phosphorylase
chr1_-_97661668 1.23 ENSMUST00000153115.1
ENSMUST00000142234.1
D1Ertd622e
DNA segment, Chr 1, ERATO Doi 622, expressed
chr3_-_69004565 1.21 ENSMUST00000169064.1
Ift80
intraflagellar transport 80
chr4_+_140701466 1.18 ENSMUST00000038893.5
ENSMUST00000138808.1
Rcc2
regulator of chromosome condensation 2
chr7_+_90130227 1.16 ENSMUST00000049537.7
Picalm
phosphatidylinositol binding clathrin assembly protein
chr8_-_34965631 1.14 ENSMUST00000033929.4
Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chrX_-_53269786 1.13 ENSMUST00000114841.1
ENSMUST00000071023.5
Fam122b
family with sequence similarity 122, member B
chr8_+_57488053 1.12 ENSMUST00000180690.1
2500002B13Rik
RIKEN cDNA 2500002B13 gene
chr1_-_97661950 1.11 ENSMUST00000053033.7
ENSMUST00000149927.1
D1Ertd622e
DNA segment, Chr 1, ERATO Doi 622, expressed
chrX_-_48454152 1.11 ENSMUST00000114958.1
Elf4
E74-like factor 4 (ets domain transcription factor)
chr3_-_69004503 1.10 ENSMUST00000107812.1
Ift80
intraflagellar transport 80
chr11_-_69900886 1.10 ENSMUST00000108621.2
ENSMUST00000100969.2
2810408A11Rik
RIKEN cDNA 2810408A11 gene
chr2_-_168590191 1.07 ENSMUST00000029057.6
ENSMUST00000074618.3
Nfatc2
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
chr1_+_156558759 1.06 ENSMUST00000173929.1
Abl2
v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
chr7_+_100372224 1.03 ENSMUST00000051777.8
ENSMUST00000098259.4
C2cd3
C2 calcium-dependent domain containing 3
chr1_+_127774164 1.01 ENSMUST00000027587.8
ENSMUST00000112570.1
Ccnt2
cyclin T2
chr16_-_4719078 0.99 ENSMUST00000120056.1
ENSMUST00000074970.7
Nmral1
NmrA-like family domain containing 1
chr12_+_11265867 0.98 ENSMUST00000020931.5
Smc6
structural maintenance of chromosomes 6
chr6_+_4903350 0.98 ENSMUST00000175962.1
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr11_+_55213783 0.96 ENSMUST00000108867.1
Slc36a1
solute carrier family 36 (proton/amino acid symporter), member 1
chr17_+_35841491 0.96 ENSMUST00000082337.6
Mdc1
mediator of DNA damage checkpoint 1
chr10_-_61784014 0.95 ENSMUST00000020283.4
H2afy2
H2A histone family, member Y2
chr19_+_8723478 0.92 ENSMUST00000180819.1
ENSMUST00000181422.1
Snhg1
small nucleolar RNA host gene (non-protein coding) 1
chr11_+_101552188 0.90 ENSMUST00000147239.1
Nbr1
neighbor of Brca1 gene 1
chr16_-_31081363 0.89 ENSMUST00000055389.7
Xxylt1
xyloside xylosyltransferase 1
chr8_-_119605199 0.88 ENSMUST00000093099.6
Taf1c
TATA box binding protein (Tbp)-associated factor, RNA polymerase I, C
chr15_-_80083374 0.87 ENSMUST00000081650.7
Rpl3
ribosomal protein L3
chr8_-_57487801 0.87 ENSMUST00000034022.3
Sap30
sin3 associated polypeptide
chr12_+_111538819 0.85 ENSMUST00000050993.9
Eif5
eukaryotic translation initiation factor 5
chr11_+_69655314 0.85 ENSMUST00000047373.5
Sox15
SRY-box containing gene 15
chr17_+_29032664 0.83 ENSMUST00000130216.1
Srsf3
serine/arginine-rich splicing factor 3
chr13_-_21531032 0.83 ENSMUST00000156674.2
ENSMUST00000110481.2
Zkscan8
zinc finger with KRAB and SCAN domains 8
chr5_-_65697856 0.80 ENSMUST00000031104.6
Pds5a
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr19_+_32485751 0.80 ENSMUST00000025827.8
Minpp1
multiple inositol polyphosphate histidine phosphatase 1
chr11_+_115564434 0.80 ENSMUST00000021085.4
Nup85
nucleoporin 85
chr12_+_112146187 0.79 ENSMUST00000128402.2
Kif26a
kinesin family member 26A
chr5_-_122900267 0.78 ENSMUST00000031435.7
Kdm2b
lysine (K)-specific demethylase 2B
chr13_+_55445301 0.77 ENSMUST00000001115.8
ENSMUST00000099482.3
Grk6
G protein-coupled receptor kinase 6
chr12_-_69681795 0.76 ENSMUST00000183277.1
ENSMUST00000035773.7
Sos2
son of sevenless homolog 2 (Drosophila)
chr6_-_51469869 0.75 ENSMUST00000114459.1
ENSMUST00000069949.6
Hnrnpa2b1
heterogeneous nuclear ribonucleoprotein A2/B1
chr5_+_32611171 0.74 ENSMUST00000072311.6
ENSMUST00000168707.2
Yes1
Yamaguchi sarcoma viral (v-yes) oncogene homolog 1
chr17_+_69417441 0.74 ENSMUST00000097289.2
C030034I22Rik
RIKEN cDNA C030034I22 gene
chr6_-_51469836 0.71 ENSMUST00000090002.7
Hnrnpa2b1
heterogeneous nuclear ribonucleoprotein A2/B1
chr11_+_73240310 0.70 ENSMUST00000138853.1
Trpv1
transient receptor potential cation channel, subfamily V, member 1
chr11_-_97500340 0.70 ENSMUST00000056955.1
4933428G20Rik
RIKEN cDNA 4933428G20 gene
chr19_+_10525244 0.70 ENSMUST00000038379.3
Cpsf7
cleavage and polyadenylation specific factor 7
chr2_+_150909565 0.69 ENSMUST00000028948.4
Gins1
GINS complex subunit 1 (Psf1 homolog)
chr16_+_20696175 0.66 ENSMUST00000128273.1
Fam131a
family with sequence similarity 131, member A
chr2_+_113327756 0.65 ENSMUST00000102547.3
Fmn1
formin 1
chr11_-_100759942 0.64 ENSMUST00000107363.2
Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr12_+_80945520 0.64 ENSMUST00000110354.1
ENSMUST00000110352.3
ENSMUST00000110351.1
ENSMUST00000110356.2
Srsf5
serine/arginine-rich splicing factor 5
chr19_+_41482632 0.62 ENSMUST00000067795.5
Lcor
ligand dependent nuclear receptor corepressor
chr10_-_30600662 0.61 ENSMUST00000019927.6
Trmt11
tRNA methyltransferase 11
chr13_-_55329723 0.60 ENSMUST00000021941.7
Mxd3
Max dimerization protein 3
chr3_+_66985680 0.60 ENSMUST00000065047.6
Rsrc1
arginine/serine-rich coiled-coil 1
chr18_+_31789120 0.59 ENSMUST00000025106.3
Polr2d
polymerase (RNA) II (DNA directed) polypeptide D
chr5_+_74535535 0.59 ENSMUST00000121950.1
Fip1l1
FIP1 like 1 (S. cerevisiae)
chr12_+_84100654 0.59 ENSMUST00000056822.3
Acot6
acyl-CoA thioesterase 6
chr9_-_96631487 0.59 ENSMUST00000128346.1
ENSMUST00000034984.6
Rasa2
RAS p21 protein activator 2
chr3_-_127553233 0.56 ENSMUST00000029588.5
Larp7
La ribonucleoprotein domain family, member 7
chr13_-_9764865 0.55 ENSMUST00000128658.1
Zmynd11
zinc finger, MYND domain containing 11
chr11_-_94549165 0.55 ENSMUST00000040487.3
Rsad1
radical S-adenosyl methionine domain containing 1
chr9_+_57076343 0.55 ENSMUST00000168678.1
Sin3a
transcriptional regulator, SIN3A (yeast)
chr10_+_112928501 0.55 ENSMUST00000180464.1
Gm26596
predicted gene, 26596
chr10_+_93589413 0.54 ENSMUST00000181835.1
4933408J17Rik
RIKEN cDNA 4933408J17 gene
chr12_-_21373606 0.54 ENSMUST00000064536.6
Adam17
a disintegrin and metallopeptidase domain 17
chr8_+_105860634 0.53 ENSMUST00000008594.7
Nutf2
nuclear transport factor 2
chr3_-_51340628 0.52 ENSMUST00000062009.7
Elf2
E74-like factor 2
chr4_-_34614886 0.52 ENSMUST00000140334.1
ENSMUST00000108142.1
ENSMUST00000048706.3
Orc3
origin recognition complex, subunit 3
chr5_-_33936301 0.52 ENSMUST00000030993.6
Nelfa
negative elongation factor complex member A, Whsc2
chr12_-_21373550 0.51 ENSMUST00000101551.3
Adam17
a disintegrin and metallopeptidase domain 17
chr5_-_39644597 0.51 ENSMUST00000152057.1
Hs3st1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr7_-_142372210 0.51 ENSMUST00000084412.5
Ifitm10
interferon induced transmembrane protein 10
chr6_-_72345144 0.50 ENSMUST00000070345.3
Usp39
ubiquitin specific peptidase 39
chr2_-_25224653 0.50 ENSMUST00000043584.4
Tubb4b
tubulin, beta 4B class IVB
chr4_-_148287927 0.50 ENSMUST00000047720.8
Ptchd2
patched domain containing 2
chr17_-_74294834 0.49 ENSMUST00000078459.6
Memo1
mediator of cell motility 1
chr11_+_68901538 0.49 ENSMUST00000073471.6
ENSMUST00000101014.2
ENSMUST00000128952.1
ENSMUST00000167436.1
Rpl26
ribosomal protein L26
chr6_+_71831441 0.49 ENSMUST00000171057.1
Immt
inner membrane protein, mitochondrial
chr16_+_43889896 0.49 ENSMUST00000122014.1
ENSMUST00000178400.1
2610015P09Rik
RIKEN cDNA 2610015P09 gene
chr17_+_47688992 0.48 ENSMUST00000156118.1
Frs3
fibroblast growth factor receptor substrate 3
chr8_+_121950492 0.47 ENSMUST00000093078.6
ENSMUST00000170857.1
ENSMUST00000026354.8
ENSMUST00000174753.1
ENSMUST00000172511.1
Banp
BTG3 associated nuclear protein
chr2_+_16356744 0.46 ENSMUST00000114703.3
Plxdc2
plexin domain containing 2
chr5_+_74535449 0.46 ENSMUST00000080164.5
ENSMUST00000113536.1
ENSMUST00000122245.1
ENSMUST00000120618.1
ENSMUST00000113535.2
ENSMUST00000113534.2
Fip1l1
FIP1 like 1 (S. cerevisiae)
chr6_+_57580992 0.45 ENSMUST00000031817.8
Herc6
hect domain and RLD 6
chr9_-_62980874 0.45 ENSMUST00000098651.4
Pias1
protein inhibitor of activated STAT 1
chr16_+_43889936 0.45 ENSMUST00000151183.1
2610015P09Rik
RIKEN cDNA 2610015P09 gene
chr3_-_51340555 0.45 ENSMUST00000091144.4
Elf2
E74-like factor 2
chr7_-_25816616 0.44 ENSMUST00000043314.3
Cyp2s1
cytochrome P450, family 2, subfamily s, polypeptide 1
chr12_+_24651346 0.44 ENSMUST00000020982.5
Klf11
Kruppel-like factor 11
chr1_+_139422196 0.43 ENSMUST00000039867.7
Zbtb41
zinc finger and BTB domain containing 41 homolog
chr14_-_30626196 0.43 ENSMUST00000112210.3
ENSMUST00000112211.2
ENSMUST00000112208.1
Prkcd
protein kinase C, delta
chr5_+_150952607 0.43 ENSMUST00000078856.6
Kl
klotho
chr18_+_44380479 0.42 ENSMUST00000025350.8
Dcp2
DCP2 decapping enzyme homolog (S. cerevisiae)
chr17_-_67354459 0.42 ENSMUST00000037974.8
Ptprm
protein tyrosine phosphatase, receptor type, M
chr10_+_81233147 0.41 ENSMUST00000144087.1
ENSMUST00000117798.1
Zfr2
zinc finger RNA binding protein 2
chr16_+_91647859 0.41 ENSMUST00000119368.1
ENSMUST00000114037.2
ENSMUST00000114036.2
ENSMUST00000122302.1
Son
Son DNA binding protein
chr12_-_100899436 0.40 ENSMUST00000053668.3
Gpr68
G protein-coupled receptor 68
chr14_+_30716377 0.40 ENSMUST00000112177.1
Sfmbt1
Scm-like with four mbt domains 1
chr11_-_86544754 0.40 ENSMUST00000138810.1
ENSMUST00000058286.2
ENSMUST00000154617.1
Rps6kb1
ribosomal protein S6 kinase, polypeptide 1
chr4_+_132768325 0.39 ENSMUST00000102561.4
Rpa2
replication protein A2

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.4 GO:0045660 positive regulation of neutrophil differentiation(GO:0045660)
2.1 6.2 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751) regulation of cGMP-mediated signaling(GO:0010752)
1.4 4.2 GO:2000371 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
1.1 5.4 GO:0034092 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
1.0 3.0 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
1.0 6.9 GO:0010032 meiotic chromosome condensation(GO:0010032)
1.0 5.8 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.8 2.4 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.7 2.2 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.7 4.0 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.6 2.5 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.6 3.0 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.6 0.6 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.6 4.1 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.6 2.3 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.5 3.7 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.5 4.7 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.5 3.4 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.5 3.7 GO:0042148 strand invasion(GO:0042148)
0.4 2.2 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.4 5.8 GO:0033504 floor plate development(GO:0033504)
0.4 4.2 GO:0035879 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.3 1.0 GO:0019085 early viral transcription(GO:0019085)
0.3 2.3 GO:0048478 replication fork protection(GO:0048478)
0.3 4.1 GO:0000212 meiotic spindle organization(GO:0000212)
0.3 2.5 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.3 2.1 GO:0019985 translesion synthesis(GO:0019985)
0.3 2.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.3 0.8 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718) myoblast development(GO:0048627)
0.3 3.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.3 1.6 GO:1904179 positive regulation of adipose tissue development(GO:1904179)
0.3 1.6 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.3 1.1 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.3 1.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.2 6.2 GO:0043486 histone exchange(GO:0043486)
0.2 2.0 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.2 1.0 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.2 1.5 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.2 1.7 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.2 3.1 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.2 1.2 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) negative regulation of metalloendopeptidase activity(GO:1904684) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.2 1.9 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 1.6 GO:0036337 Fas signaling pathway(GO:0036337)
0.2 2.8 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 1.8 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.2 7.8 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.2 4.7 GO:0072520 seminiferous tubule development(GO:0072520)
0.2 2.3 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.2 1.0 GO:0061511 centriole elongation(GO:0061511)
0.2 3.0 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.2 1.6 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.2 0.8 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.2 1.2 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.2 0.8 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.2 1.1 GO:0001866 NK T cell proliferation(GO:0001866)
0.2 0.7 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.2 2.8 GO:0015809 arginine transport(GO:0015809)
0.2 0.5 GO:0090204 protein localization to nuclear pore(GO:0090204) negative regulation of vascular endothelial growth factor production(GO:1904046)
0.2 0.5 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2 2.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.2 0.5 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.2 1.0 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.2 1.0 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.2 0.8 GO:0021993 initiation of neural tube closure(GO:0021993)
0.2 2.7 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 1.3 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.8 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.1 0.9 GO:0016266 O-glycan processing(GO:0016266)
0.1 1.0 GO:0015808 L-alanine transport(GO:0015808)
0.1 0.7 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 1.8 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1 0.4 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.7 GO:1902969 mitotic DNA replication(GO:1902969)
0.1 2.2 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 1.0 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.4 GO:0060697 glucosylceramide catabolic process(GO:0006680) positive regulation of phospholipid catabolic process(GO:0060697)
0.1 0.4 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1 0.3 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.1 4.8 GO:0000266 mitochondrial fission(GO:0000266)
0.1 1.6 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 0.3 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.9 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 0.4 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 1.7 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.6 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.1 0.7 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.1 1.5 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 2.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 0.5 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 0.8 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 1.3 GO:0009251 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.4 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.5 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 1.8 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 1.1 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 1.1 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.2 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.3 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.2 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
0.0 0.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.9 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.5 GO:0001755 neural crest cell migration(GO:0001755)
0.0 1.0 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 2.5 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.8 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.9 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 1.3 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.3 GO:0032274 gonadotropin secretion(GO:0032274)
0.0 0.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.4 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.3 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.7 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.1 GO:0015824 proline transport(GO:0015824)
0.0 0.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 3.3 GO:0045444 fat cell differentiation(GO:0045444)
0.0 0.6 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 0.8 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0035542 negative regulation of vesicle fusion(GO:0031339) regulation of SNARE complex assembly(GO:0035542) negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.0 0.2 GO:0060033 anatomical structure regression(GO:0060033)
0.0 1.5 GO:0007631 feeding behavior(GO:0007631)
0.0 2.7 GO:0032496 response to lipopolysaccharide(GO:0032496)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0000799 nuclear condensin complex(GO:0000799)
1.1 4.2 GO:1990707 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
1.0 6.9 GO:0000796 condensin complex(GO:0000796)
0.8 4.0 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.7 0.7 GO:0000811 GINS complex(GO:0000811)
0.7 6.2 GO:0005577 fibrinogen complex(GO:0005577)
0.7 4.7 GO:0005828 kinetochore microtubule(GO:0005828)
0.7 7.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.5 2.7 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.5 0.5 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.5 3.0 GO:0070531 BRCA1-A complex(GO:0070531)
0.4 4.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.4 1.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.4 1.5 GO:0005594 collagen type IX trimer(GO:0005594)
0.4 1.5 GO:0005610 laminin-5 complex(GO:0005610) laminin-10 complex(GO:0043259)
0.4 1.8 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.3 2.3 GO:0031298 replication fork protection complex(GO:0031298)
0.3 2.0 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.3 1.0 GO:0035061 interchromatin granule(GO:0035061)
0.3 2.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2 1.5 GO:0005638 lamin filament(GO:0005638)
0.2 1.0 GO:1990761 growth cone lamellipodium(GO:1990761)
0.2 2.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 0.9 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.2 1.9 GO:0071439 clathrin complex(GO:0071439)
0.1 3.1 GO:0016580 Sin3 complex(GO:0016580)
0.1 1.0 GO:0001740 Barr body(GO:0001740)
0.1 0.5 GO:0032021 NELF complex(GO:0032021)
0.1 4.0 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 5.2 GO:0016592 mediator complex(GO:0016592)
0.1 1.5 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 1.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 1.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.1 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 1.0 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 2.5 GO:0034451 centriolar satellite(GO:0034451)
0.1 3.5 GO:0002102 podosome(GO:0002102)
0.1 0.8 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.5 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 2.3 GO:0035869 ciliary transition zone(GO:0035869)
0.1 1.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.3 GO:0001891 phagocytic cup(GO:0001891)
0.1 4.1 GO:0072686 mitotic spindle(GO:0072686)
0.1 5.8 GO:0005814 centriole(GO:0005814)
0.1 4.2 GO:0005776 autophagosome(GO:0005776)
0.0 0.5 GO:0045298 tubulin complex(GO:0045298)
0.0 1.4 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 2.1 GO:0005871 kinesin complex(GO:0005871)
0.0 3.6 GO:0016605 PML body(GO:0016605)
0.0 0.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.4 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 3.7 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 3.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.7 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 2.3 GO:0005581 collagen trimer(GO:0005581)
0.0 1.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 6.2 GO:0005925 focal adhesion(GO:0005925)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.8 GO:0031519 PcG protein complex(GO:0031519)
0.0 1.7 GO:0001650 fibrillar center(GO:0001650)
0.0 0.3 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.2 GO:0070052 collagen V binding(GO:0070052)
1.2 5.8 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.7 4.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.6 3.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.6 4.2 GO:0015616 DNA translocase activity(GO:0015616)
0.6 1.7 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637)
0.5 2.7 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.5 3.7 GO:0000150 recombinase activity(GO:0000150)
0.5 2.0 GO:0036033 mediator complex binding(GO:0036033)
0.4 2.5 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.4 2.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.4 3.4 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.4 2.8 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.3 1.0 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
0.3 1.3 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.3 4.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 1.5 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 1.6 GO:0032184 SUMO polymer binding(GO:0032184)
0.2 2.7 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.2 7.4 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.2 4.4 GO:0042608 T cell receptor binding(GO:0042608)
0.2 0.8 GO:0052743 inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.2 0.8 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 0.8 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.2 1.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 1.1 GO:0050733 RS domain binding(GO:0050733)
0.1 0.9 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 1.3 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 4.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.9 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.4 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 4.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.4 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 1.0 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 2.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.6 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.7 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.1 1.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 4.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.4 GO:0070976 TIR domain binding(GO:0070976)
0.1 0.4 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 0.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 1.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 3.7 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 0.8 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 2.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.3 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 1.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.9 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1 0.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.3 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 5.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 0.7 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 0.9 GO:0008097 5S rRNA binding(GO:0008097)
0.1 3.0 GO:0003684 damaged DNA binding(GO:0003684)
0.1 0.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.3 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 5.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 1.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 3.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 2.5 GO:0005158 insulin receptor binding(GO:0005158)
0.1 1.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.7 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 3.4 GO:0030276 clathrin binding(GO:0030276)
0.0 0.8 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.1 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 1.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 3.2 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 2.0 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.5 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 5.0 GO:0042393 histone binding(GO:0042393)
0.0 0.3 GO:0034595 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.0 5.0 GO:0008234 cysteine-type peptidase activity(GO:0008234)
0.0 1.3 GO:0019843 rRNA binding(GO:0019843)
0.0 0.5 GO:0030332 cyclin binding(GO:0030332)
0.0 1.4 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.0 0.4 GO:0070330 aromatase activity(GO:0070330)
0.0 3.7 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.4 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 14.6 PID ATM PATHWAY ATM pathway
0.2 11.1 PID AURORA B PATHWAY Aurora B signaling
0.2 1.6 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.2 5.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 5.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 1.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 7.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 1.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 1.0 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 2.7 PID ATR PATHWAY ATR signaling pathway
0.1 2.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 2.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 2.0 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 4.3 PID E2F PATHWAY E2F transcription factor network
0.0 1.2 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 2.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.8 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.5 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 2.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.1 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.5 PID SHP2 PATHWAY SHP2 signaling
0.0 3.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID CXCR4 PATHWAY CXCR4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 11.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.3 4.0 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.2 0.2 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.2 4.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.2 5.5 REACTOME KINESINS Genes involved in Kinesins
0.2 5.8 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.2 4.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.8 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 7.0 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 0.7 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 1.6 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 2.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.1 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 7.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 2.5 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.1 0.5 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 1.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 3.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.2 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 0.9 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 0.5 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 2.9 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 2.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 2.3 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 1.6 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 2.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 5.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.5 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 2.0 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.9 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 2.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.9 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.0 1.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.2 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.9 REACTOME TRANSLATION Genes involved in Translation